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Conserved domains on  [gi|757775520|ref|WP_042994610|]
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MULTISPECIES: carbohydrate ABC transporter permease [Bifidobacterium]

Protein Classification

carbohydrate ABC transporter permease( domain architecture ID 11417684)

carbohydrate ABC transporter permease, part of a periplasmic binding protein (PBP)-dependent ABC transporter may be involved in transport of one or more of a variety of mono-, di-, or polysaccharides, such as trehalose/maltose (MalG) and alginate (AlgM); responsible for translocation of the substrate across the membrane

Gene Ontology:  GO:0055085|GO:0008643
PubMed:  19234479|27273632
TCDB:  3.A.1.1.

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 6-282 4.12e-83

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


:

Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 251.17  E-value: 4.12e-83
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520   6 AKAEKFRKDRRINWWLTAVVAVFSLTILVPLYFTVVTALKTPAEAGTFS---LPTSWQWGNFAAASAKVDYPRAALNSAI 82
Cdd:COG0395    2 SATARRRRRRLGRILLYLLLILLALLFLFPLYWMVVTSFKPPAEIFSGPpslLPSEFTLENYRAAFTDGPFGRYLLNSLI 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520  83 ITVLAVSLTLVTNTFVAYAIARnMDKRFFRFLYYFFIAAMFVPFPVVMLPLAKQMGSWHL-DNQAGLIVLYVILGLGTNL 161
Cdd:COG0395   82 VAVVSTVLSLLLSSLAAYALAR-FRFRGRKLLFLLILATLMIPGQVLLIPLYLLFRQLGLlNTYWGLILPYLAFGLPFGI 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520 162 FIATGFIRSIPVSLEEAARIDGAGTWRIFWKIIFPLMGPINATIAIMTALWAWNDFLLPLIILTDQSNQTIPLAQYVFSS 241
Cdd:COG0395  161 FLLRQFFRSIPRELEEAARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGLASFQG 240

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 757775520 242 QFATNYPQAFASYLMAMAPVLVVYIFAQKWVVGGVMRGAVK 282
Cdd:COG0395  241 QYGTDWGLLMAAAVIATLPVLILFLFLQRYFVRGLTAGAVK 281
 
Name Accession Description Interval E-value
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 6-282 4.12e-83

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 251.17  E-value: 4.12e-83
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520   6 AKAEKFRKDRRINWWLTAVVAVFSLTILVPLYFTVVTALKTPAEAGTFS---LPTSWQWGNFAAASAKVDYPRAALNSAI 82
Cdd:COG0395    2 SATARRRRRRLGRILLYLLLILLALLFLFPLYWMVVTSFKPPAEIFSGPpslLPSEFTLENYRAAFTDGPFGRYLLNSLI 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520  83 ITVLAVSLTLVTNTFVAYAIARnMDKRFFRFLYYFFIAAMFVPFPVVMLPLAKQMGSWHL-DNQAGLIVLYVILGLGTNL 161
Cdd:COG0395   82 VAVVSTVLSLLLSSLAAYALAR-FRFRGRKLLFLLILATLMIPGQVLLIPLYLLFRQLGLlNTYWGLILPYLAFGLPFGI 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520 162 FIATGFIRSIPVSLEEAARIDGAGTWRIFWKIIFPLMGPINATIAIMTALWAWNDFLLPLIILTDQSNQTIPLAQYVFSS 241
Cdd:COG0395  161 FLLRQFFRSIPRELEEAARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGLASFQG 240

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 757775520 242 QFATNYPQAFASYLMAMAPVLVVYIFAQKWVVGGVMRGAVK 282
Cdd:COG0395  241 QYGTDWGLLMAAAVIATLPVLILFLFLQRYFVRGLTAGAVK 281
ABC_arch_GlcU NF040932
glucose ABC transporter permease GlcU;
24-277 3.33e-33

glucose ABC transporter permease GlcU;


Pssm-ID: 468865  Cd Length: 272  Bit Score: 122.42  E-value: 3.33e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520  24 VVAVFSLTILVPLYFTVVTALKTPAEAGT---FSLPTSWQWGNFAAASAKVDYPraALNSAIITVLAVSLTLVTNTFVAY 100
Cdd:NF040932   8 VLVILVIIWLIPLYAMVINGLKSNFEVLStpvLVPPSKPTLSAYYTVWSGLAPP--LINSLIVVIPVALISTFLGAMGAY 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520 101 AIARNMDKRFFRFLYYFFIAAM--FVPFPVVMLPLAKQMGSWHLDNQ-AGLIVLYVILGLGTNLFIATGFIRSIPVSLEE 177
Cdd:NF040932  86 FFYRLSERHSILSDFLFSLIALatFIPYQATLVPLTRLEVSLGLFNTyWGLIFALLIFYIPTAALLMSIFIPVLPKYLIE 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520 178 AARIDGAGTWRIFWKIIFPLMGPINATIAIMTALWAWNDFLLPLIILTDQSNQTIPLAQYVFSSQFATNYPQAFASYLMA 257
Cdd:NF040932 166 AARIDGASDWTIFWKVVLPLTVPGFISTLIFIFIESWNNFFIPLVLTTTPSMRLIPVAVRSYTGGYGTLYNESFAAAVIA 245

                        250       260
                 ....*....|....*....|
gi 757775520 258 MAPVLVVYIFAQKWVVGGVM 277
Cdd:NF040932 246 SIVPLLIFIFLGRYFIRGLA 265
malG PRK10998
maltose ABC transporter permease MalG;
79-282 2.48e-15

maltose ABC transporter permease MalG;


Pssm-ID: 182891  Cd Length: 296  Bit Score: 74.36  E-value: 2.48e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520  79 NSAIITVLAVSLTLVTNTFVAYAIARNMDKRFFRFLYYFFIAAMF------VPFPVVMLPLAKQMGSWHLDNQAGLIVLY 152
Cdd:PRK10998  87 NSVKVAGITAIGIVALSTTCAYAFARMRFKGKATLLKGMLIFQMFpavlslVALYALFDRLGQYIPFIGLNTHGGVIFAY 166

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520 153 ViLGLGTNLFIATGFIRSIPVSLEEAARIDGAGTWRIFWKIIFPLMGPINATIAIMTALWAWNDFLLPLIILTDQSNQTI 232
Cdd:PRK10998 167 L-GGIALHVWTIKGYFETIDSSLEEAAALDGATPWQAFRLVLLPLSVPILAVVFILSFIAAITEVPVASLLLRDVNSYTL 245

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 757775520 233 PLA--QYVfssqfatnYPQAF------ASYLMAMAPVLVVYIFAQKWVVGGVMRGAVK 282
Cdd:PRK10998 246 AVGmqQYL--------NPQNYlwgdfaAAAVLSAIPITVVFLLAQRWLVGGLTAGGVK 295
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 96-268 4.90e-12

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 63.09  E-value: 4.90e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520   96 TFVAYAIARNMDKRFFRFLYYFFIAAMFVPFPVVMLPL--AKQMGSWHLDNQAGLIvLYVILGLGTNLFIATGFIRSIPV 173
Cdd:pfam00528   2 IPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLvvIAILSILGHGILPAII-LALLGWAGYARLIRRAALRSLPS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520  174 SLEEAARIDGAGTWRIFWKIIFPLMGPINATIAIMTALWAWNDFLLPLIILTDQsnqtiPLAQYVFSSQFATNYPQAFAS 253
Cdd:pfam00528  81 DLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWP-----GLGLLLIEAILGYDYPEIQGP 155

                         170
                  ....*....|....*
gi 757775520  254 YLMAMAPVLVVYIFA 268
Cdd:pfam00528 156 VLAAALILLLLNLLV 170
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 77-262 9.74e-12

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 62.30  E-value: 9.74e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520  77 ALNSAIITVLAVSLTLVTNTFVAYAIARNMDKRFFRFLYYFFIAaMFVPFPVVMLPLA---KQMGSWHLDNQAGL--IVL 151
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLL-LSLPSLVLGLLLVllfGVLLGWGILPGLGLpaLIL 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520 152 YVILGLGTNLFIATGFIRSIPVSLEEAARIDGAGTWRIFWKIIFPLMGPINATIAIMTALWAWNDFLLPLIILTDQSNQT 231
Cdd:cd06261   80 ALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGP 159

                        170       180       190
                 ....*....|....*....|....*....|.
gi 757775520 232 IPLAQYVFSSQFATNYPQAFASYLMAMAPVL 262
Cdd:cd06261  160 GTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
 
Name Accession Description Interval E-value
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 6-282 4.12e-83

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 251.17  E-value: 4.12e-83
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520   6 AKAEKFRKDRRINWWLTAVVAVFSLTILVPLYFTVVTALKTPAEAGTFS---LPTSWQWGNFAAASAKVDYPRAALNSAI 82
Cdd:COG0395    2 SATARRRRRRLGRILLYLLLILLALLFLFPLYWMVVTSFKPPAEIFSGPpslLPSEFTLENYRAAFTDGPFGRYLLNSLI 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520  83 ITVLAVSLTLVTNTFVAYAIARnMDKRFFRFLYYFFIAAMFVPFPVVMLPLAKQMGSWHL-DNQAGLIVLYVILGLGTNL 161
Cdd:COG0395   82 VAVVSTVLSLLLSSLAAYALAR-FRFRGRKLLFLLILATLMIPGQVLLIPLYLLFRQLGLlNTYWGLILPYLAFGLPFGI 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520 162 FIATGFIRSIPVSLEEAARIDGAGTWRIFWKIIFPLMGPINATIAIMTALWAWNDFLLPLIILTDQSNQTIPLAQYVFSS 241
Cdd:COG0395  161 FLLRQFFRSIPRELEEAARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGLASFQG 240

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 757775520 242 QFATNYPQAFASYLMAMAPVLVVYIFAQKWVVGGVMRGAVK 282
Cdd:COG0395  241 QYGTDWGLLMAAAVIATLPVLILFLFLQRYFVRGLTAGAVK 281
MalG COG3833
ABC-type maltose transport system, permease component MalG [Carbohydrate transport and ...
 10-282 3.45e-54

ABC-type maltose transport system, permease component MalG [Carbohydrate transport and metabolism];


Pssm-ID: 443045 [Multi-domain]  Cd Length: 282  Bit Score: 176.88  E-value: 3.45e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520  10 KFRKDRRINWWLTAVVAVFSLTILVPLYFTVVTAL-KTPAEAGTFSLPTSWQWGNFAAASAKVDYPRAALNSAIITVLAV 88
Cdd:COG3833    7 RKRRRRLKLGLRHLVLIILAIIALFPILWVVSASFnPGGSLYSSSLIPENFTLENYKKLFTETPFLRWFLNSLIVAVVTA 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520  89 SLTLVTNTFVAYAIARNMDKRFFRFLYYFFIAAMFvPFPVVMLP---LAKQMGSwhLDNQAGLIVLYVILGLGTNLFIAT 165
Cdd:COG3833   87 IISVFLAALAAYAFSRFRFKGRKAGLLALLLLQMF-PAFLALVAlylLLSALGL--LNTLLGLILVYLGGAIPFNTWLMK 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520 166 GFIRSIPVSLEEAARIDGAGTWRIFWKIIFPLMGPINATIAIMTALWAWNDFLLPLIILTDQSNQTIPLAQYVF-SSQFA 244
Cdd:COG3833  164 GYFDTIPKELDEAAKIDGASHFQIFFRIILPLAKPILAVVALLSFIGPWNDFILASVLLRSPENYTLAVGLYSFvSDQRN 243

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 757775520 245 TNYPQAFASYLMAMAPVLVVYIFAQKWVVGGVMRGAVK 282
Cdd:COG3833  244 TNWGVFAAGAVLVAIPIVILFLFLQRYLVSGLTAGGVK 281
ABC_arch_GlcU NF040932
glucose ABC transporter permease GlcU;
24-277 3.33e-33

glucose ABC transporter permease GlcU;


Pssm-ID: 468865  Cd Length: 272  Bit Score: 122.42  E-value: 3.33e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520  24 VVAVFSLTILVPLYFTVVTALKTPAEAGT---FSLPTSWQWGNFAAASAKVDYPraALNSAIITVLAVSLTLVTNTFVAY 100
Cdd:NF040932   8 VLVILVIIWLIPLYAMVINGLKSNFEVLStpvLVPPSKPTLSAYYTVWSGLAPP--LINSLIVVIPVALISTFLGAMGAY 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520 101 AIARNMDKRFFRFLYYFFIAAM--FVPFPVVMLPLAKQMGSWHLDNQ-AGLIVLYVILGLGTNLFIATGFIRSIPVSLEE 177
Cdd:NF040932  86 FFYRLSERHSILSDFLFSLIALatFIPYQATLVPLTRLEVSLGLFNTyWGLIFALLIFYIPTAALLMSIFIPVLPKYLIE 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520 178 AARIDGAGTWRIFWKIIFPLMGPINATIAIMTALWAWNDFLLPLIILTDQSNQTIPLAQYVFSSQFATNYPQAFASYLMA 257
Cdd:NF040932 166 AARIDGASDWTIFWKVVLPLTVPGFISTLIFIFIESWNNFFIPLVLTTTPSMRLIPVAVRSYTGGYGTLYNESFAAAVIA 245

                        250       260
                 ....*....|....*....|
gi 757775520 258 MAPVLVVYIFAQKWVVGGVM 277
Cdd:NF040932 246 SIVPLLIFIFLGRYFIRGLA 265
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
3-268 3.87e-17

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 79.41  E-value: 3.87e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520   3 TAPAKAEKFRKDRRINWWLTA-VVAVFSLTILVPLYFTVVTALktpAEAGTFSLPTSWQ-WGNFAAASAKVDYPRAALNS 80
Cdd:COG1175    5 TSAAARRRRRRRRLAAYLFLLpALLLLLVFVLYPLLYTLYLSF---TDWNLLGPPPEFVgLDNYARLFTDPRFWNALGNT 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520  81 AIITVLAVSLTLVTNTFVAYAIARNMdkrffrFLYYFFIAAMFVPF---PVVMLPLAKQM------------GSWHLDNQ 145
Cdd:COG1175   82 LLFTVVSVPLQLVLGLLLALLLNRKL------RGRGFFRTLFFLPWvisPVVVALIWKWLfnpdygllnallGALGLEPI 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520 146 A----------GLIVLYVILGLGTNLFIATGFIRSIPVSLEEAARIDGAGTWRIFWKIIFPLMGPINATIAIMTALWAWN 215
Cdd:COG1175  156 NwlgdpslalpAVIIVTVWKGTGFNMLIFLAGLQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIGALQ 235

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 757775520 216 DFLLPLiILTDQ--SNQTIPLAQYVFSSQFaTNYPQAFASylmAMAPVLVVYIFA 268
Cdd:COG1175  236 VFDLVY-VLTGGgpGNSTTTLVLYIYQTAF-QQFDFGYAS---AIAVVLFLIILV 285
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 13-272 1.89e-16

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 77.07  E-value: 1.89e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520  13 KDRRINWWLTAVVAVFSLTILVPLYFTVVTALkTPAEAGTFsLPTSWQWGNFAAASAKVDYPRAALNSAIITVLAVSLTL 92
Cdd:COG1177    1 SSRLGRLLLRLFLALVLLFLYLPILVLVLYSF-NDSWFLTF-PPEGFTLRWYAELFSDPRLLDALLNSLLIALLSTLLAT 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520  93 VTNTFVAYAIARnMDKRFFRFLYYFFIAAMFVPFPVVMLPLAKQMGSWHLDNQAGLIVL-YVILGLGTNLFIATGFIRSI 171
Cdd:COG1177   79 VLGTPAALALAR-YRFRGRRLLLALLLLPLVVPGIVLGVALLLLFSALGLSGGLWGLILaHVVFTLPFVVLVVLARLQGF 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520 172 PVSLEEAARIDGAGTWRIFWKIIFPLMGPINATIAIMTALWAWNDFLLPLiILTDQSNQTIPLaqYVFSSQFATNYPQAF 251
Cdd:COG1177  158 DPSLEEAARDLGASPWQTFRRVTLPLIAPGILAGALLAFTLSFDEFVITL-FLAGPGVTTLPV--YIYSMIRRGISPEIN 234

                        250       260
                 ....*....|....*....|.
gi 757775520 252 ASYLMAMAPVLVVYIFAQKWV 272
Cdd:COG1177  235 ALSTLLILLSLLLLLLAERLR 255
malG PRK10998
maltose ABC transporter permease MalG;
79-282 2.48e-15

maltose ABC transporter permease MalG;


Pssm-ID: 182891  Cd Length: 296  Bit Score: 74.36  E-value: 2.48e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520  79 NSAIITVLAVSLTLVTNTFVAYAIARNMDKRFFRFLYYFFIAAMF------VPFPVVMLPLAKQMGSWHLDNQAGLIVLY 152
Cdd:PRK10998  87 NSVKVAGITAIGIVALSTTCAYAFARMRFKGKATLLKGMLIFQMFpavlslVALYALFDRLGQYIPFIGLNTHGGVIFAY 166

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520 153 ViLGLGTNLFIATGFIRSIPVSLEEAARIDGAGTWRIFWKIIFPLMGPINATIAIMTALWAWNDFLLPLIILTDQSNQTI 232
Cdd:PRK10998 167 L-GGIALHVWTIKGYFETIDSSLEEAAALDGATPWQAFRLVLLPLSVPILAVVFILSFIAAITEVPVASLLLRDVNSYTL 245

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 757775520 233 PLA--QYVfssqfatnYPQAF------ASYLMAMAPVLVVYIFAQKWVVGGVMRGAVK 282
Cdd:PRK10998 246 AVGmqQYL--------NPQNYlwgdfaAAAVLSAIPITVVFLLAQRWLVGGLTAGGVK 295
PRK10973 PRK10973
sn-glycerol-3-phosphate ABC transporter permease UgpE;
23-277 2.88e-15

sn-glycerol-3-phosphate ABC transporter permease UgpE;


Pssm-ID: 182875 [Multi-domain]  Cd Length: 281  Bit Score: 74.00  E-value: 2.88e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520  23 AVVAVFSLTILVPLYFTVVTALKTPAEAGTFSL---PTSWQWGNFA------AASAKVDYPRAALNSAIITVLAVSLTLV 93
Cdd:PRK10973  14 TMLILGIAVILFPLYVAFVAATLDKQAVFAVPMtliPGTHLLENIAniwvngVGNNSAPFGRMLLNSFVMAFSITVGKIT 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520  94 TNTFVAYAIARNMDKRFFRFLYYFFIAAMfVPFPVVMLPLAKQMGSWHLDNQAGLIVLYVILGlGTNLFIATGFIRSIPV 173
Cdd:PRK10973  94 VSMLSAFAIVWFRFPLRNLFFWMIFITLM-LPVEVRIFPTVEVIANLKMLDSYAGLTLPLMAS-ATATFLFRQFFMTLPD 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520 174 SLEEAARIDGAGTWRIFWKIIFPLMGPINATIAIMTALWAWNDFLLPLIILTDQSNQT--IPLAQYVFSSQFATNYPQAF 251
Cdd:PRK10973 172 ELVEAARIDGASPMRFFWDIVLPLSKTNLAALFVITFIYGWNQYLWPLLIITDVSLGTavAGIKGMIATGEGTTEWNQVM 251

                        250       260
                 ....*....|....*....|....*.
gi 757775520 252 ASYLMAMAPVLVVYIFAQKWVVGGVM 277
Cdd:PRK10973 252 AAMLLTLIPPVVIVLAMQRAFVRGLV 277
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
5-269 4.24e-12

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 65.95  E-value: 4.24e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520   5 PAKAEKFRKDRRINWWLTAVVAVFSLTILVPLYFTVVTALKTpaeagtfSLPTSWQWGNFAAASAKVDYPRAALNSAIIT 84
Cdd:COG1178  275 ARRPRRVKLGRWRWLALALCLLLVLLGLLLPLLALLLWSLTK-------ALDDNLTLDNYRFVLLDPSLLRALLNSLLLA 347

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520  85 VLAVSLTLVTNTFVAYAIARNMDKRFFRFLYYFFIAAMfVPFPVV----MLPLAKQMGSWHLDNQAGLIVLYVILGLGTN 160
Cdd:COG1178  348 LLAALLAVLLALLLAYLVRRRRGRLARLLDRLAMLPYA-VPGIVLglglLLLFNRPLPLLLYGTLAILVLAYVVRFLPFA 426

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520 161 LFIATGFIRSIPVSLEEAARIDGAGTWRIFWKIIFPLMGPINATIAIMTALWAWNDflLPL-IILTDQSNQTIPLAQYVF 239
Cdd:COG1178  427 LRSLEAALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALLVFVTSMKE--LSAtLLLRPPGFETLAVLIYQL 504

                        250       260       270
                 ....*....|....*....|....*....|
gi 757775520 240 SSQFATNYPQAFASYLMAMAPVLVVYIFAQ 269
Cdd:COG1178  505 ASSGRYGEAAALALLLVLVSLLPVLLLERL 534
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 96-268 4.90e-12

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 63.09  E-value: 4.90e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520   96 TFVAYAIARNMDKRFFRFLYYFFIAAMFVPFPVVMLPL--AKQMGSWHLDNQAGLIvLYVILGLGTNLFIATGFIRSIPV 173
Cdd:pfam00528   2 IPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLvvIAILSILGHGILPAII-LALLGWAGYARLIRRAALRSLPS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520  174 SLEEAARIDGAGTWRIFWKIIFPLMGPINATIAIMTALWAWNDFLLPLIILTDQsnqtiPLAQYVFSSQFATNYPQAFAS 253
Cdd:pfam00528  81 DLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWP-----GLGLLLIEAILGYDYPEIQGP 155

                         170
                  ....*....|....*
gi 757775520  254 YLMAMAPVLVVYIFA 268
Cdd:pfam00528 156 VLAAALILLLLNLLV 170
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 77-262 9.74e-12

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 62.30  E-value: 9.74e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520  77 ALNSAIITVLAVSLTLVTNTFVAYAIARNMDKRFFRFLYYFFIAaMFVPFPVVMLPLA---KQMGSWHLDNQAGL--IVL 151
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLL-LSLPSLVLGLLLVllfGVLLGWGILPGLGLpaLIL 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520 152 YVILGLGTNLFIATGFIRSIPVSLEEAARIDGAGTWRIFWKIIFPLMGPINATIAIMTALWAWNDFLLPLIILTDQSNQT 231
Cdd:cd06261   80 ALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGP 159

                        170       180       190
                 ....*....|....*....|....*....|.
gi 757775520 232 IPLAQYVFSSQFATNYPQAFASYLMAMAPVL 262
Cdd:cd06261  160 GTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 8-272 3.71e-11

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 62.09  E-value: 3.71e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520   8 AEKFRKDRRINWWLTAVVAVFSLTILVPLYFTVVTALKTPAEAGTFSlpTSWQWGNFAAASAKVDYPRAALNSAIITVLA 87
Cdd:COG1176    2 SAALRRRLRPLLLLLPALLWLLLFFVLPLLLLLVYSFTTRDPYGGVV--PGFTLENYARLFTDPLYLKVLLRTLWIALLT 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520  88 VSLTLVTNTFVAYAIARnMDKRFFRFLYYFFIAAMFVPFPVVML----------PLAKQMGSWHLDNQAgLIVLY----V 153
Cdd:COG1176   80 TLICLLLGYPIAYFLAR-APPRWRNLLLLLVILPFWTSFLVRTYawivllgrngLLNSLLLALGLIDEP-LRLLYtefaV 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520 154 ILGLGTNLF------IATGfIRSIPVSLEEAARIDGAGTWRIFWKIIFPLMGPINATIAIMTALWAWNDFLLPLIIltdQ 227
Cdd:COG1176  158 VIGLVYVYLpfmvlpLYAA-LEKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLVFIPALGAFVTPALL---G 233

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 757775520 228 SNQTIPLAQYVFSSQFAT-NYPQAFASYLMAMAPVLVVYIFAQKWV 272
Cdd:COG1176  234 GGKVLMIGNLIYQQFLSAlNWPLAAALAVVLLLIVLLVLLLYLRLL 279
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
12-275 3.73e-11

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 63.26  E-value: 3.73e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520  12 RKDRRINWWLTAVVAVFSLTILVPLYFTVVTALktpaeagtfslptSWQWGNFAAASAKVDYPRAALNSAIITVLAVSLT 91
Cdd:COG1178    4 RPRRRPRLLLLLLALLLALLVLLPLLALLLRAF-------------TDGLANFWALLSDPYLWRALGNTLLLALLVTLLS 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520  92 LVTNTFVAYAIARnMDKRFFRFLYYFFIAAMFVPfPVVM-----------------LPLAKQMGSWHLDNQAGLIVLYVI 154
Cdd:COG1178   71 LLLGVPLAWLLAR-TDFPGRRLLRWLLLLPLALP-PYVValawialfgpngllntlLRALFGLEPPDIYGLGGIILVLVL 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757775520 155 LGLGTNLFIATGFIRSIPVSLEEAARIDGAGTWRIFWKIIFPLMGPINATIAIMTALWAWNDFLLPLIIltDQSNQTIPL 234
Cdd:COG1178  149 FNYPYVYLLLRAALRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAIAAGALLVFLLCLADFGTPLVL--GGGYTTLTT 226

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 757775520 235 AQYV-FSSQFatNYPQAFASYLMAMAPVLVVyIFAQKWVVGG 275
Cdd:COG1178  227 AIYQaWLGDF--DLGAAAALALVLLLLVLLL-LLLERRLRRR 265
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 161-200 9.08e-05

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 42.81  E-value: 9.08e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 757775520 161 LFIATGF--------IRSIPVSLEEAARIDGAGTWRIFWKIIFPLMGP 200
Cdd:COG0555  144 TFVSLPFvvrtvqpvLEELDPELEEAAATLGASRWQTFRRVILPLLLP 191
malF PRK10999
maltose ABC transporter permease MalF;
163-215 9.35e-05

maltose ABC transporter permease MalF;


Pssm-ID: 236816 [Multi-domain]  Cd Length: 520  Bit Score: 43.41  E-value: 9.35e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 757775520 163 IATGFIRSIPVSLEEAARIDGAGTWRIFWKIIFPLMgpINATIAIMTALWAWN 215
Cdd:PRK10999 393 LCMGLLKAIPDDLYEASAMDGAGPFQNFFKITLPLL--IKPLTPLMIASFAFN 443
LplB COG4209
ABC-type polysaccharide transport system, permease component [Carbohydrate transport and ...
 155-211 1.44e-04

ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 443357 [Multi-domain]  Cd Length: 316  Bit Score: 42.38  E-value: 1.44e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 757775520 155 LGLGTNLFIATgfIRSIPVSLEEAARIDGAGTWRIFWKIIFPLMGPinaTIAIMTAL 211
Cdd:COG4209  189 AGWGSIIYLAA--ITGIDPELYEAAAIDGAGRWQQIWHITLPGIRP---TIVILLIL 240
cysT CHL00187
sulfate transport protein; Provisional
 168-200 1.38e-03

sulfate transport protein; Provisional


Pssm-ID: 214388 [Multi-domain]  Cd Length: 237  Bit Score: 39.23  E-value: 1.38e-03
                         10        20        30
                 ....*....|....*....|....*....|...
gi 757775520 168 IRSIPVSLEEAARIDGAGTWRIFWKIIFPLMGP 200
Cdd:CHL00187 160 LQEIEKELEEAAWSLGASPWQTFWKVIFPPLIP 192
PRK10561 PRK10561
sn-glycerol-3-phosphate ABC transporter permease UgpA;
168-216 1.79e-03

sn-glycerol-3-phosphate ABC transporter permease UgpA;


Pssm-ID: 182550 [Multi-domain]  Cd Length: 280  Bit Score: 39.04  E-value: 1.79e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 757775520 168 IRSIPVSLEEAARIDGAGTWRIFWKIIFPLMGPINATIAIMTALWAWND 216
Cdd:PRK10561 166 LQSIPRSLVEAAAIDGAGPIRRFFKLALPLIAPVSFFLLVVNLVYAFFD 214
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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