benzoate 1,2-dioxygenase small subunit [Agrobacterium fabrum]
nuclear transport factor 2 family protein( domain architecture ID 233)
nuclear transport factor 2 (NTF2) family protein, similar to Aspergillus flavus scytalone dehydratases, Pseudomonas putida benzene 1,2-dioxygenase subunit beta, and many other members with similar structural details but divergent functions
List of domain hits
Name | Accession | Description | Interval | E-value | |||
NTF2_like super family | cl09109 | Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 ... |
8-163 | 3.99e-85 | |||
Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of divergent evolution wherein the proteins have many common structural details but diverge greatly in their function. For example, nuclear transport factor 2 (NTF2) mediates the nuclear import of RanGDP and binds to both RanGDP and FxFG repeat-containing nucleoporins while Ketosteroid isomerases catalyze the isomerization of delta-5-3-ketosteroid to delta-4-3-ketosteroid, by intramolecular transfer of the C4-beta proton to the C6-beta position. While the function of the beta sub-unit of the Ring hydroxylating dioxygenases is not known, Scytalone Dehydratases catalyzes two reactions in the biosynthetic pathway that produces fungal melanin. Members of the NTF2-like superfamily are widely distributed among bacteria, archaea and eukaryotes. The actual alignment was detected with superfamily member TIGR03232: Pssm-ID: 471850 Cd Length: 155 Bit Score: 246.65 E-value: 3.99e-85
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Name | Accession | Description | Interval | E-value | |||
benzo_1_2_benB | TIGR03232 | benzoate 1,2-dioxygenase, small subunit; Benzoate 1,2-dioxygenase (EC 1.14.12.10) belongs to ... |
8-163 | 3.99e-85 | |||
benzoate 1,2-dioxygenase, small subunit; Benzoate 1,2-dioxygenase (EC 1.14.12.10) belongs to the larger family of aromatic ring-hydroxylating dioxygenases. Members of this family should all act on benzoate, but several have additional known activities on various benozate analogs. Some members actually may be named more suitably according to such alternate an activity, such as 2-chlorobenzoate 1,2-dioxygenase (1.14.12.13). Pssm-ID: 132276 Cd Length: 155 Bit Score: 246.65 E-value: 3.99e-85
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ring_hydroxylating_dioxygenases_beta | cd00667 | Ring hydroxylating dioxygenase beta subunit. This subunit has a similar structure to NTF-2, ... |
5-162 | 2.03e-53 | |||
Ring hydroxylating dioxygenase beta subunit. This subunit has a similar structure to NTF-2, Ketosteroid isomerase and scytalone dehydratase.The degradation of aromatic compounds by aerobic bacteria frequently begins with the dihydroxylation of the substrate by nonheme iron-containing dioxygenases. These enzymes consist of two or three soluble proteins that interact to form an electron-transport chain that transfers electrons from reduced nucleotides (NADH) via flavin and [2Fe-2S] redox centers to a terminal dioxygenase. Aromatic-ring-hydroxylating dioxygenases oxidize aromatic hydrocarbons and related compounds to cis-arene diols. These enzymes utilize a mononuclear non-heme iron center to catalyze the addition of dioxygen to their respective substrates. The active site of these enzymes however is in the alpha sub-unit. No functional role has been attributed to the beta sub-unit except for a structural role. Pssm-ID: 238357 Cd Length: 160 Bit Score: 166.67 E-value: 2.03e-53
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HcaF | COG5517 | 3-phenylpropionate/cinnamic acid dioxygenase, small subunit [Secondary metabolites ... |
5-163 | 2.97e-50 | |||
3-phenylpropionate/cinnamic acid dioxygenase, small subunit [Secondary metabolites biosynthesis, transport and catabolism]; Pssm-ID: 444268 Cd Length: 162 Bit Score: 158.47 E-value: 2.97e-50
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Ring_hydroxyl_B | pfam00866 | Ring hydroxylating beta subunit; This subunit has a similar structure to NTF-2 and scytalone ... |
14-154 | 3.82e-47 | |||
Ring hydroxylating beta subunit; This subunit has a similar structure to NTF-2 and scytalone dehydratase. Pssm-ID: 425916 Cd Length: 144 Bit Score: 150.14 E-value: 3.82e-47
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PRK10069 | PRK10069 | 3-phenylpropionate/cinnamic acid dioxygenase subunit beta; |
6-149 | 2.47e-14 | |||
3-phenylpropionate/cinnamic acid dioxygenase subunit beta; Pssm-ID: 236647 Cd Length: 183 Bit Score: 66.97 E-value: 2.47e-14
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Name | Accession | Description | Interval | E-value | |||
benzo_1_2_benB | TIGR03232 | benzoate 1,2-dioxygenase, small subunit; Benzoate 1,2-dioxygenase (EC 1.14.12.10) belongs to ... |
8-163 | 3.99e-85 | |||
benzoate 1,2-dioxygenase, small subunit; Benzoate 1,2-dioxygenase (EC 1.14.12.10) belongs to the larger family of aromatic ring-hydroxylating dioxygenases. Members of this family should all act on benzoate, but several have additional known activities on various benozate analogs. Some members actually may be named more suitably according to such alternate an activity, such as 2-chlorobenzoate 1,2-dioxygenase (1.14.12.13). Pssm-ID: 132276 Cd Length: 155 Bit Score: 246.65 E-value: 3.99e-85
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ring_hydroxylating_dioxygenases_beta | cd00667 | Ring hydroxylating dioxygenase beta subunit. This subunit has a similar structure to NTF-2, ... |
5-162 | 2.03e-53 | |||
Ring hydroxylating dioxygenase beta subunit. This subunit has a similar structure to NTF-2, Ketosteroid isomerase and scytalone dehydratase.The degradation of aromatic compounds by aerobic bacteria frequently begins with the dihydroxylation of the substrate by nonheme iron-containing dioxygenases. These enzymes consist of two or three soluble proteins that interact to form an electron-transport chain that transfers electrons from reduced nucleotides (NADH) via flavin and [2Fe-2S] redox centers to a terminal dioxygenase. Aromatic-ring-hydroxylating dioxygenases oxidize aromatic hydrocarbons and related compounds to cis-arene diols. These enzymes utilize a mononuclear non-heme iron center to catalyze the addition of dioxygen to their respective substrates. The active site of these enzymes however is in the alpha sub-unit. No functional role has been attributed to the beta sub-unit except for a structural role. Pssm-ID: 238357 Cd Length: 160 Bit Score: 166.67 E-value: 2.03e-53
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anthran_1_2_B | TIGR03231 | anthranilate 1,2-dioxygenase, small subunit; Anthranilate (2-aminobenzoate) is an intermediate ... |
8-163 | 1.03e-50 | |||
anthranilate 1,2-dioxygenase, small subunit; Anthranilate (2-aminobenzoate) is an intermediate of tryptophan (Trp) biosynthesis and degradation. Members of this family are the small subunit of anthranilate 1,2-dioxygenase, which acts in Trp degradation by converting anthranilate to catechol. Closely related paralogs typically are the benzoate 1,2-dioxygenase small subunit, among the larger set of ring-hydroxylating dioxygenases. [Energy metabolism, Amino acids and amines] Pssm-ID: 132275 Cd Length: 155 Bit Score: 159.68 E-value: 1.03e-50
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HcaF | COG5517 | 3-phenylpropionate/cinnamic acid dioxygenase, small subunit [Secondary metabolites ... |
5-163 | 2.97e-50 | |||
3-phenylpropionate/cinnamic acid dioxygenase, small subunit [Secondary metabolites biosynthesis, transport and catabolism]; Pssm-ID: 444268 Cd Length: 162 Bit Score: 158.47 E-value: 2.97e-50
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Ring_hydroxyl_B | pfam00866 | Ring hydroxylating beta subunit; This subunit has a similar structure to NTF-2 and scytalone ... |
14-154 | 3.82e-47 | |||
Ring hydroxylating beta subunit; This subunit has a similar structure to NTF-2 and scytalone dehydratase. Pssm-ID: 425916 Cd Length: 144 Bit Score: 150.14 E-value: 3.82e-47
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NTF2_like | cd00531 | Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 ... |
8-150 | 1.64e-15 | |||
Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of divergent evolution wherein the proteins have many common structural details but diverge greatly in their function. For example, nuclear transport factor 2 (NTF2) mediates the nuclear import of RanGDP and binds to both RanGDP and FxFG repeat-containing nucleoporins while Ketosteroid isomerases catalyze the isomerization of delta-5-3-ketosteroid to delta-4-3-ketosteroid, by intramolecular transfer of the C4-beta proton to the C6-beta position. While the function of the beta sub-unit of the Ring hydroxylating dioxygenases is not known, Scytalone Dehydratases catalyzes two reactions in the biosynthetic pathway that produces fungal melanin. Members of the NTF2-like superfamily are widely distributed among bacteria, archaea and eukaryotes. Pssm-ID: 238296 [Multi-domain] Cd Length: 124 Bit Score: 68.70 E-value: 1.64e-15
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PRK10069 | PRK10069 | 3-phenylpropionate/cinnamic acid dioxygenase subunit beta; |
6-149 | 2.47e-14 | |||
3-phenylpropionate/cinnamic acid dioxygenase subunit beta; Pssm-ID: 236647 Cd Length: 183 Bit Score: 66.97 E-value: 2.47e-14
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SnoaL_4 | pfam13577 | SnoaL-like domain; This family contains a large number of proteins that share the SnoaL fold. |
4-43 | 3.58e-04 | |||
SnoaL-like domain; This family contains a large number of proteins that share the SnoaL fold. Pssm-ID: 433323 [Multi-domain] Cd Length: 125 Bit Score: 38.47 E-value: 3.58e-04
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Blast search parameters | ||||
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