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Conserved domains on  [gi|697205005|ref|WP_033170469|]
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RnfABCDGE type electron transport complex subunit B [Selenomonas sp. ND2010]

Protein Classification

RnfABCDGE type electron transport complex subunit B( domain architecture ID 11482575)

RnfABCDGE type electron transport complex subunit B is part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK07118 PRK07118
Fe-S cluster domain-containing protein;
2-277 5.38e-90

Fe-S cluster domain-containing protein;


:

Pssm-ID: 235941 [Multi-domain]  Cd Length: 280  Bit Score: 268.34  E-value: 5.38e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005   2 MNTAIMIIVVLVGIGTFFGVVLALADKRFAMEVNPLIHEVEDILPKGQCGACGFAGCAKYAEAVVEDEtVPPNLCVPGKA 81
Cdd:PRK07118   1 MNMILFAVLSLGALGLVFGILLAFASKKFAVEEDPRVEAVREVLPGANCGGCGYPGCDGYAEAVVNGD-APPNLCPVGGA 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005  82 AVAAKVAELTGKKAEAAEPKYAQLKCRGTKTAAVMAARYEGIHDCAAAKLIQGGPKGCKYGCIGFGNCVRACPFGALSMg 161
Cdd:PRK07118  80 EVAEKVAEILGKEAAESEPKVAVVRCQGTCDKAKERYEYQGIKDCAAAALLFGGPKGCSYGCLGLGSCVAACPFDAIHI- 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005 162 EDGLPIVDKAICTGCGKCVSTCPQAILTLQSFEVPVQVECSSHDRGPVAKKLCQNACIGCGLCMRSCEHGAIKIDRFVAV 241
Cdd:PRK07118 159 ENGLPVVDEDKCTGCGACVKACPRNVIELIPKSARVFVACNSKDKGKAVKKVCEVGCIGCGKCVKACPAGAITMENNLAV 238

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 697205005 242 VDQEICKTCDtpTCLAKCPTKAIQELVAGRMMKEVV 277
Cdd:PRK07118 239 IDQEKCTSCG--KCVEKCPTKAIRILNKPPKVKEPK 272
 
Name Accession Description Interval E-value
PRK07118 PRK07118
Fe-S cluster domain-containing protein;
2-277 5.38e-90

Fe-S cluster domain-containing protein;


Pssm-ID: 235941 [Multi-domain]  Cd Length: 280  Bit Score: 268.34  E-value: 5.38e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005   2 MNTAIMIIVVLVGIGTFFGVVLALADKRFAMEVNPLIHEVEDILPKGQCGACGFAGCAKYAEAVVEDEtVPPNLCVPGKA 81
Cdd:PRK07118   1 MNMILFAVLSLGALGLVFGILLAFASKKFAVEEDPRVEAVREVLPGANCGGCGYPGCDGYAEAVVNGD-APPNLCPVGGA 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005  82 AVAAKVAELTGKKAEAAEPKYAQLKCRGTKTAAVMAARYEGIHDCAAAKLIQGGPKGCKYGCIGFGNCVRACPFGALSMg 161
Cdd:PRK07118  80 EVAEKVAEILGKEAAESEPKVAVVRCQGTCDKAKERYEYQGIKDCAAAALLFGGPKGCSYGCLGLGSCVAACPFDAIHI- 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005 162 EDGLPIVDKAICTGCGKCVSTCPQAILTLQSFEVPVQVECSSHDRGPVAKKLCQNACIGCGLCMRSCEHGAIKIDRFVAV 241
Cdd:PRK07118 159 ENGLPVVDEDKCTGCGACVKACPRNVIELIPKSARVFVACNSKDKGKAVKKVCEVGCIGCGKCVKACPAGAITMENNLAV 238

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 697205005 242 VDQEICKTCDtpTCLAKCPTKAIQELVAGRMMKEVV 277
Cdd:PRK07118 239 IDQEKCTSCG--KCVEKCPTKAIRILNKPPKVKEPK 272
RnfB COG2878
Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and ...
 2-264 1.28e-77

Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and conversion]; Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit is part of the Pathway/BioSystem: Na+-translocating Fd:NADH oxidoreductase


Pssm-ID: 442125 [Multi-domain]  Cd Length: 254  Bit Score: 236.04  E-value: 1.28e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005   2 MNTAIMIIVVLVGIGTFFGVVLALADKRFAMEVNPLIHEVEDILPKGQCGACGFAGCAKYAEAVVEDEtVPPNLCVPGKA 81
Cdd:COG2878    1 MSTILIAVLVLGGLGLVFGLILGYASKKFKVEEDPRVEEIDALLPGANCGQCGYPGCRPYAEAIAEGE-APINLCPPGGA 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005  82 AVAAKVAELTGKKAEAAEPKYAQLKCRGTKTAAVMAARYEGIHDCAAAKLiqGGPKGCKYGCIGFGNCVRACPFGALSMG 161
Cdd:COG2878   80 AVAEKLAELLGVEAGPLDPEVAVVRCNGGCEKAKPKYEYDGIKDCRAAVI--GGPKGCEYGCIGCGDCIKACPFDAIVGA 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005 162 EDGLPIVDKAICTGCGKCVSTCPQAILTLQSFEVPVQVecSSHDRGPVAKKlcQNACIGCglCMRSCEHGAIKIDRFVAV 241
Cdd:COG2878  158 AKGMHTVDEDKCTGCGLCVEACPVDCIEMVPVSPTVVV--SSWDKGKAVRK--VVGCIGL--CCKKCCPAAAITVNNLAA 231

                        250       260
                 ....*....|....*....|...
gi 697205005 242 VDQEICKTCdTPTCLAKCPTKAI 264
Cdd:COG2878  232 IIDYKKCTC-CGCCEKCCPTAII 253
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 136-264 5.94e-25

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 96.31  E-value: 5.94e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005 136 PKGCKYGCIGFGNCVRACPFGALSMGEDGL----PIVDKAICTGCGKCVSTCPQAILTLQSFEVPVQVECSShdrgpvaK 211
Cdd:cd10549    1 LKYDPEKCIGCGICVKACPTDAIELGPNGAiargPEIDEDKCVFCGACVEVCPTGAIELTPEGKEYVPKEKE-------A 73

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 697205005 212 KLCQNACIGCGLCMRSCEHGAIKI-DRFVAVVDQEICKTCDtpTCLAKCPTKAI 264
Cdd:cd10549   74 EIDEEKCIGCGLCVKVCPVDAITLeDELEIVIDKEKCIGCG--ICAEVCPVNAI 125
rnfB TIGR01944
electron transport complex, RnfABCDGE type, B subunit; The six subunit complex RnfABCDGE in ...
 4-191 4.52e-20

electron transport complex, RnfABCDGE type, B subunit; The six subunit complex RnfABCDGE in Rhodobacter capsulatus encodes an apparent NADH oxidoreductase responsible for electron transport to nitrogenase, necessary for nitrogen fixation. A closely related complex in E. coli, RsxABCDGE (Reducer of SoxR), reduces the 2Fe-2S-containing superoxide sensor SoxR, active as a transcription factor when oxidized. This family of putative NADH oxidoreductase complexes exists in many of the same species as the related NQR, a Na(+)-translocating NADH-quinone reductase, but is distinct. This model describes the B subunit. [Energy metabolism, Electron transport]


Pssm-ID: 273887 [Multi-domain]  Cd Length: 165  Bit Score: 84.46  E-value: 4.52e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005    4 TAIMIIVVLVGIGTFFGVVLALADKRFAMEVNPLIHEVEDILPKGQCGACGFAGCAKYAEAVVEDETVppNLCVPGKAAV 83
Cdd:TIGR01944   1 MIIAAVAALSALGLALGAILGYAARRFPVEADPIVEEIDALLPQTQCGQCGYPGCRPYAEAIAEGEAI--NKCPPGGEAV 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005   84 AAKVAELTGKKAEAAEPKYAQLKCRGTKTAAVMAARyegihdcaaakliqggpkgckygCIGFGNCVRACPFGALSMGED 163
Cdd:TIGR01944  79 ILALAELLGVEPIPQPLDADAGTIQPPMVALIDEDN-----------------------CIGCTKCIQACPVDAIVGAAK 135

                         170       180
                  ....*....|....*....|....*...
gi 697205005  164 GLPIVDKAICTGCGKCVSTCPQAILTLQ 191
Cdd:TIGR01944 136 AMHTVIADECTGCDLCVEPCPTDCIEMI 163
FeS pfam04060
Putative Fe-S cluster; This family includes a domain with four conserved cysteines that ...
 45-78 7.01e-06

Putative Fe-S cluster; This family includes a domain with four conserved cysteines that probably form an Fe-S redox cluster.


Pssm-ID: 461150 [Multi-domain]  Cd Length: 33  Bit Score: 42.03  E-value: 7.01e-06
                          10        20        30
                  ....*....|....*....|....*....|....
gi 697205005   45 LPKGQCGACGFAGCAKYAEAVVEDEtVPPNLCVP 78
Cdd:pfam04060   1 LPGTNCGACGYPGCRAFAEAVVAGE-AKINDCPP 33
ferrodoxin_EFR1 NF038196
EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight ...
 216-265 4.84e-03

EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight conserved Cys residues in two CxxCxxCxxxCP motifs, each of which binds a 4Fe-4S cluster. The N-terminal region resembles flavodoxin domains, with some members of the family recognized by Pfam models PF12724 (Flavodoxin_5) or PF00258 (Flavodoxin_1).


Pssm-ID: 468407 [Multi-domain]  Cd Length: 243  Bit Score: 37.53  E-value: 4.84e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 697205005 216 NACIGCGLCMRSCEHGAIKIdrfvavVDQEI-----CKTCdtPTCLAKCPTKAIQ 265
Cdd:NF038196 185 DKCIGCGICAKVCPVNNIEM------EDGKPvwghnCTHC--LACIHRCPKEAIE 231
ferrodoxin_EFR1 NF038196
EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight ...
 143-187 5.35e-03

EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight conserved Cys residues in two CxxCxxCxxxCP motifs, each of which binds a 4Fe-4S cluster. The N-terminal region resembles flavodoxin domains, with some members of the family recognized by Pfam models PF12724 (Flavodoxin_5) or PF00258 (Flavodoxin_1).


Pssm-ID: 468407 [Multi-domain]  Cd Length: 243  Bit Score: 37.53  E-value: 5.35e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 697205005 143 CIGFGNCVRACPFGALSMgEDGLPIVDKAiCTGCGKCVSTCPQ-AI 187
Cdd:NF038196 187 CIGCGICAKVCPVNNIEM-EDGKPVWGHN-CTHCLACIHRCPKeAI 230
 
Name Accession Description Interval E-value
PRK07118 PRK07118
Fe-S cluster domain-containing protein;
2-277 5.38e-90

Fe-S cluster domain-containing protein;


Pssm-ID: 235941 [Multi-domain]  Cd Length: 280  Bit Score: 268.34  E-value: 5.38e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005   2 MNTAIMIIVVLVGIGTFFGVVLALADKRFAMEVNPLIHEVEDILPKGQCGACGFAGCAKYAEAVVEDEtVPPNLCVPGKA 81
Cdd:PRK07118   1 MNMILFAVLSLGALGLVFGILLAFASKKFAVEEDPRVEAVREVLPGANCGGCGYPGCDGYAEAVVNGD-APPNLCPVGGA 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005  82 AVAAKVAELTGKKAEAAEPKYAQLKCRGTKTAAVMAARYEGIHDCAAAKLIQGGPKGCKYGCIGFGNCVRACPFGALSMg 161
Cdd:PRK07118  80 EVAEKVAEILGKEAAESEPKVAVVRCQGTCDKAKERYEYQGIKDCAAAALLFGGPKGCSYGCLGLGSCVAACPFDAIHI- 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005 162 EDGLPIVDKAICTGCGKCVSTCPQAILTLQSFEVPVQVECSSHDRGPVAKKLCQNACIGCGLCMRSCEHGAIKIDRFVAV 241
Cdd:PRK07118 159 ENGLPVVDEDKCTGCGACVKACPRNVIELIPKSARVFVACNSKDKGKAVKKVCEVGCIGCGKCVKACPAGAITMENNLAV 238

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 697205005 242 VDQEICKTCDtpTCLAKCPTKAIQELVAGRMMKEVV 277
Cdd:PRK07118 239 IDQEKCTSCG--KCVEKCPTKAIRILNKPPKVKEPK 272
RnfB COG2878
Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and ...
 2-264 1.28e-77

Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and conversion]; Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit is part of the Pathway/BioSystem: Na+-translocating Fd:NADH oxidoreductase


Pssm-ID: 442125 [Multi-domain]  Cd Length: 254  Bit Score: 236.04  E-value: 1.28e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005   2 MNTAIMIIVVLVGIGTFFGVVLALADKRFAMEVNPLIHEVEDILPKGQCGACGFAGCAKYAEAVVEDEtVPPNLCVPGKA 81
Cdd:COG2878    1 MSTILIAVLVLGGLGLVFGLILGYASKKFKVEEDPRVEEIDALLPGANCGQCGYPGCRPYAEAIAEGE-APINLCPPGGA 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005  82 AVAAKVAELTGKKAEAAEPKYAQLKCRGTKTAAVMAARYEGIHDCAAAKLiqGGPKGCKYGCIGFGNCVRACPFGALSMG 161
Cdd:COG2878   80 AVAEKLAELLGVEAGPLDPEVAVVRCNGGCEKAKPKYEYDGIKDCRAAVI--GGPKGCEYGCIGCGDCIKACPFDAIVGA 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005 162 EDGLPIVDKAICTGCGKCVSTCPQAILTLQSFEVPVQVecSSHDRGPVAKKlcQNACIGCglCMRSCEHGAIKIDRFVAV 241
Cdd:COG2878  158 AKGMHTVDEDKCTGCGLCVEACPVDCIEMVPVSPTVVV--SSWDKGKAVRK--VVGCIGL--CCKKCCPAAAITVNNLAA 231

                        250       260
                 ....*....|....*....|...
gi 697205005 242 VDQEICKTCdTPTCLAKCPTKAI 264
Cdd:COG2878  232 IIDYKKCTC-CGCCEKCCPTAII 253
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 136-264 5.94e-25

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 96.31  E-value: 5.94e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005 136 PKGCKYGCIGFGNCVRACPFGALSMGEDGL----PIVDKAICTGCGKCVSTCPQAILTLQSFEVPVQVECSShdrgpvaK 211
Cdd:cd10549    1 LKYDPEKCIGCGICVKACPTDAIELGPNGAiargPEIDEDKCVFCGACVEVCPTGAIELTPEGKEYVPKEKE-------A 73

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 697205005 212 KLCQNACIGCGLCMRSCEHGAIKI-DRFVAVVDQEICKTCDtpTCLAKCPTKAI 264
Cdd:cd10549   74 EIDEEKCIGCGLCVKVCPVDAITLeDELEIVIDKEKCIGCG--ICAEVCPVNAI 125
PRK05113 PRK05113
electron transport complex protein RnfB; Provisional
 2-184 8.08e-22

electron transport complex protein RnfB; Provisional


Pssm-ID: 235347 [Multi-domain]  Cd Length: 191  Bit Score: 90.00  E-value: 8.08e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005   2 MNTAIMIIVVLVGIGTFFGVVLALADKRFAMEVNPLIHEVEDILPKGQCGACGFAGCAKYAEAVVEDETVppNLCVPGKA 81
Cdd:PRK05113   1 MSAIWIAVAALSLLALVFGAILGFASRRFKVEGDPIVEKIDAILPQSQCGQCGYPGCRPYAEAIANGEKI--NKCPPGGE 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005  82 AVAAKVAELTGKKAEAAEpkyaqlkcrGTKTAAVMAARYEGIHDCAaakliqggpkgckygCIGFGNCVRACPFGALSMG 161
Cdd:PRK05113  79 ATMLKLAELLGVEPQPLD---------GEAQEATPARKVAFIDEDN---------------CIGCTKCIQACPVDAIVGA 134

                        170       180
                 ....*....|....*....|...
gi 697205005 162 EDGLPIVDKAICTGCGKCVSTCP 184
Cdd:PRK05113 135 TKAMHTVISDLCTGCDLCVAPCP 157
rnfB TIGR01944
electron transport complex, RnfABCDGE type, B subunit; The six subunit complex RnfABCDGE in ...
 4-191 4.52e-20

electron transport complex, RnfABCDGE type, B subunit; The six subunit complex RnfABCDGE in Rhodobacter capsulatus encodes an apparent NADH oxidoreductase responsible for electron transport to nitrogenase, necessary for nitrogen fixation. A closely related complex in E. coli, RsxABCDGE (Reducer of SoxR), reduces the 2Fe-2S-containing superoxide sensor SoxR, active as a transcription factor when oxidized. This family of putative NADH oxidoreductase complexes exists in many of the same species as the related NQR, a Na(+)-translocating NADH-quinone reductase, but is distinct. This model describes the B subunit. [Energy metabolism, Electron transport]


Pssm-ID: 273887 [Multi-domain]  Cd Length: 165  Bit Score: 84.46  E-value: 4.52e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005    4 TAIMIIVVLVGIGTFFGVVLALADKRFAMEVNPLIHEVEDILPKGQCGACGFAGCAKYAEAVVEDETVppNLCVPGKAAV 83
Cdd:TIGR01944   1 MIIAAVAALSALGLALGAILGYAARRFPVEADPIVEEIDALLPQTQCGQCGYPGCRPYAEAIAEGEAI--NKCPPGGEAV 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005   84 AAKVAELTGKKAEAAEPKYAQLKCRGTKTAAVMAARyegihdcaaakliqggpkgckygCIGFGNCVRACPFGALSMGED 163
Cdd:TIGR01944  79 ILALAELLGVEPIPQPLDADAGTIQPPMVALIDEDN-----------------------CIGCTKCIQACPVDAIVGAAK 135

                         170       180
                  ....*....|....*....|....*...
gi 697205005  164 GLPIVDKAICTGCGKCVSTCPQAILTLQ 191
Cdd:TIGR01944 136 AMHTVIADECTGCDLCVEPCPTDCIEMI 163
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
143-195 1.28e-12

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 67.58  E-value: 1.28e-12
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 697205005 143 CIGFGNCVRACPFGALSMGEDGLPIVDKAICTGCGKCVSTCPQAILTLQSFEV 195
Cdd:COG1148  498 CTGCGRCVEVCPYGAISIDEKGVAEVNPALCKGCGTCAAACPSGAISLKGFTD 550
PRK06991 PRK06991
electron transport complex subunit RsxB;
32-184 2.00e-11

electron transport complex subunit RsxB;


Pssm-ID: 235903 [Multi-domain]  Cd Length: 270  Bit Score: 62.89  E-value: 2.00e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005  32 MEVNPLIHEVEDILPKGQCGACGFAGCAKYAEAVVEDETvPPNLCVPGKAAVAAKVAELTGKKAEAAEPKyaqlkcRGTK 111
Cdd:PRK06991   2 TDSKTLADRIEDLLPQTQCTKCGYDGCRPYAEAIAAGEA-NYNRCPPGGAEGIARLAALLGKPVIPLDPA------NGVE 74

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 697205005 112 TAAVMAARYEGIhdcaaakliqggpkgckygCIGFGNCVRACPFGALSMGEDGLPIVDKAICTGCGKCVSTCP 184
Cdd:PRK06991  75 RPRAVAVIDEQL-------------------CIGCTLCMQACPVDAIVGAPKQMHTVLADLCTGCDLCVPPCP 128
NapF_like cd10564
NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, ...
 143-265 4.03e-11

NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, the iron-sulfur subunit of periplasmic nitrate reductase. The periplasmic nitrate reductase NapABC of Escherichia coli likely functions during anaerobic growth in low-nitrate environments; napF operon expression is activated by cyclic AMP receptor protein (Crp). NapF is a subfamily of the beta subunit of DMSO reductase (DMSOR) family. DMSOR family members have a large, periplasmic molybdenum-containing alpha subunit as well as a small beta FeS subunit, and may also have a small gamma subunit. The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319886 [Multi-domain]  Cd Length: 139  Bit Score: 59.56  E-value: 4.03e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005 143 CIGFGNCVRACPFGALSMGEDGLPIVD--KAICTGCGKCVSTCPQAILTLQSFE-VPVQVECSSHdrgpvakklCQN-AC 218
Cdd:cd10564   15 CTRCGDCVEACPEGIIVRGDGGFPELDfsRGECTFCGACAEACPEGALDPAREApWPLRAEIGDS---------CLAlQG 85

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 697205005 219 IGCGLCMRSCEHGAIKI-----DRFVAVVDQEICKTCDtpTCLAKCPTKAIQ 265
Cdd:cd10564   86 VECRSCQDACPTQAIRFrprlgGIALPELDADACTGCG--ACVSVCPVGAIT 135
PRK08764 PRK08764
Rnf electron transport complex subunit RnfB;
36-184 1.17e-10

Rnf electron transport complex subunit RnfB;


Pssm-ID: 181550 [Multi-domain]  Cd Length: 135  Bit Score: 58.01  E-value: 1.17e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005  36 PLIHEVEDILPKGQCGACGFAGCAKYAEAVVEDETVPpNLCVPGKAAVAAKVAELTGKKAEAAEpkyaqlKCRGTKTAAV 115
Cdd:PRK08764   6 TLVERLDRLLPQTQCGQCGFDGCRPYAQAMARGEATI-DRCPPGGDAGARALAQVLGVPARPYD------RSRGTHKLPQ 78

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 697205005 116 MAARYEGihdcaaakliqggpkgckyGCIGFGNCVRACPFGALSMGEDGLPIVDKAICTGCGKCVSTCP 184
Cdd:PRK08764  79 VAWIVEA-------------------DCIGCTKCIQACPVDAIVGGAKHMHTVIAPLCTGCELCVPACP 128
COG1149 COG1149
MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...
 143-195 7.50e-10

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];


Pssm-ID: 440763 [Multi-domain]  Cd Length: 68  Bit Score: 53.96  E-value: 7.50e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 697205005 143 CIGFGNCVRACPFGALSMGEDGLPIVDKAICTGCGKCVSTCPQAILTLQSFEV 195
Cdd:COG1149   13 CIGCGLCVEVCPEGAIKLDDGGAPVVDPDLCTGCGACVGVCPTGAITLEEREA 65
COG2768 COG2768
Uncharacterized Fe-S cluster protein [Function unknown];
215-265 7.21e-09

Uncharacterized Fe-S cluster protein [Function unknown];


Pssm-ID: 442050 [Multi-domain]  Cd Length: 74  Bit Score: 51.66  E-value: 7.21e-09
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 697205005 215 QNACIGCGLCMRSCEHGAIKIDRFVAVVDQEICKTCdtPTCLAKCPTKAIQ 265
Cdd:COG2768   10 EEKCIGCGACVKVCPVGAISIEDGKAVIDPEKCIGC--GACIEVCPVGAIK 58
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 140-191 2.17e-08

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 51.63  E-value: 2.17e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 697205005 140 KYGCIGFGNCVRACPFGALSMGEDGLPIVDKAICTGCGKCVSTCPQAILTLQ 191
Cdd:cd10549   77 EEKCIGCGLCVKVCPVDAITLEDELEIVIDKEKCIGCGICAEVCPVNAIKLV 128
DsrA COG2221
Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion ...
 143-189 2.64e-08

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion transport and metabolism];


Pssm-ID: 441823 [Multi-domain]  Cd Length: 69  Bit Score: 49.66  E-value: 2.64e-08
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 697205005 143 CIGFGNCVRACPFGALSMgEDGLPIVDKAICTGCGKCVSTCPQAILT 189
Cdd:COG2221   17 CIGCGLCVAVCPTGAISL-DDGKLVIDEEKCIGCGACIRVCPTGAIK 62
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
215-265 2.94e-08

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 54.10  E-value: 2.94e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 697205005 215 QNACIGCGLCMRSCEHGAIKID-RFVAVVDQEICKTCDTptCLAKCPTKAIQ 265
Cdd:COG1148  495 PEKCTGCGRCVEVCPYGAISIDeKGVAEVNPALCKGCGT--CAAACPSGAIS 544
DsrA COG2221
Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion ...
 207-264 6.20e-08

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion transport and metabolism];


Pssm-ID: 441823 [Multi-domain]  Cd Length: 69  Bit Score: 48.89  E-value: 6.20e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 697205005 207 GPVAKKLCQNACIGCGLCMRSCEHGAIKIDRFVAVVDQEICKTCDtpTCLAKCPTKAI 264
Cdd:COG2221    6 GTWPPKIDEEKCIGCGLCVAVCPTGAISLDDGKLVIDEEKCIGCG--ACIRVCPTGAI 61
Nar1 COG4624
Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];
115-185 7.35e-08

Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];


Pssm-ID: 443663 [Multi-domain]  Cd Length: 450  Bit Score: 52.72  E-value: 7.35e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 697205005 115 VMAARYEGIHDCAAAKLIQGGPKGCKYGCIGFGNCVRACPFGALSMGEDGLPIVDKAiCTGCGKCVSTCPQ 185
Cdd:COG4624   65 CVAISCIQVRGIIIIDKRGPSIIRDKEKCKNCYPCVRACPVKAIKVDDGKAEIDEEK-CISCGQCVAVCPF 134
DMSOR_beta-like cd04410
Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta ...
 149-235 7.57e-08

Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319870 [Multi-domain]  Cd Length: 136  Bit Score: 50.47  E-value: 7.57e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005 149 CVRACPFGALSMGEDGLPIVDKAICTGCGKCVSTCPqailtlqsFEVPVQVEcsshDRGPVAKklcqnaCIGCG------ 222
Cdd:cd04410   58 CVKACPTGAIYKDEDGIVLIDEDKCIGCGSCVEACP--------YGAIVFDP----EPGKAVK------CDLCGdrldeg 119

                         90
                 ....*....|....*.
gi 697205005 223 ---LCMRSCEHGAIKI 235
Cdd:cd04410  120 lepACVKACPTGALTF 135
COG2768 COG2768
Uncharacterized Fe-S cluster protein [Function unknown];
143-185 7.68e-08

Uncharacterized Fe-S cluster protein [Function unknown];


Pssm-ID: 442050 [Multi-domain]  Cd Length: 74  Bit Score: 48.57  E-value: 7.68e-08
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 697205005 143 CIGFGNCVRACPFGALSMGEDGLPIvDKAICTGCGKCVSTCPQ 185
Cdd:COG2768   13 CIGCGACVKVCPVGAISIEDGKAVI-DPEKCIGCGACIEVCPV 54
DsrA COG2221
Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion ...
 166-237 1.23e-07

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion transport and metabolism];


Pssm-ID: 441823 [Multi-domain]  Cd Length: 69  Bit Score: 47.74  E-value: 1.23e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 697205005 166 PIVDKAICTGCGKCVSTCPQAILTLQSFEVPVQVEcsshdrgpvakklcqnACIGCGLCMRSCEHGAIKIDR 237
Cdd:COG2221   10 PKIDEEKCIGCGLCVAVCPTGAISLDDGKLVIDEE----------------KCIGCGACIRVCPTGAIKGEK 65
DMSOR_beta_like cd16372
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 143-235 1.52e-07

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319894 [Multi-domain]  Cd Length: 125  Bit Score: 49.26  E-value: 1.52e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005 143 CIGFGNCVRACPFGALSMGEDGLPIVDKAICTGCGKCVSTCPqailtlqsFEVPVQvecssHDRGPVAKKlcqnaCIGCG 222
Cdd:cd16372   49 CNQCGECIDVCPTGAITRDANGVVMINKKLCVGCLMCVGFCP--------EGAMFK-----HEDYPEPFK-----CIACG 110

                         90
                 ....*....|...
gi 697205005 223 LCMRSCEHGAIKI 235
Cdd:cd16372  111 ICVKACPTGALEL 123
NuoI COG1143
Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy ...
 143-197 1.64e-07

Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy production and conversion]; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440758 [Multi-domain]  Cd Length: 66  Bit Score: 47.43  E-value: 1.64e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 697205005 143 CIGFGNCVRACPFGALSMGEDGL---PIVDKAICTGCGKCVSTCPQAILTLQSFEVPV 197
Cdd:COG1143    4 CIGCGLCVRVCPVDAITIEDGEPgkvYVIDPDKCIGCGLCVEVCPTGAISMTPFELAV 61
PRK13795 PRK13795
hypothetical protein; Provisional
 141-184 1.85e-07

hypothetical protein; Provisional


Pssm-ID: 237510 [Multi-domain]  Cd Length: 636  Bit Score: 51.92  E-value: 1.85e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 697205005 141 YGCIGFGNCVRACPFGALSMGEDGLPI-VDKAICTGCGKCVSTCP 184
Cdd:PRK13795 581 AECVGCGVCVGACPTGAIRIEEGKRKIsVDEEKCIHCGKCTEVCP 625
PorD COG1144
Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta ...
 143-190 1.94e-07

Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit [Energy production and conversion]; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit is part of the Pathway/BioSystem: Pyruvate oxidation


Pssm-ID: 440759 [Multi-domain]  Cd Length: 84  Bit Score: 47.74  E-value: 1.94e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 697205005 143 CIGFGNCVRACPFGALSMGEDGLPIVDKAICTGCGKCVSTCPQAILTL 190
Cdd:COG1144   32 CIGCGLCWIVCPDGAIRVDDGKYYGIDYDYCKGCGICAEVCPVKAIEM 79
HybA COG0437
Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and ...
 149-235 4.46e-07

Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and conversion];


Pssm-ID: 440206 [Multi-domain]  Cd Length: 184  Bit Score: 49.17  E-value: 4.46e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005 149 CVRACPFGALSMGEDGLPIVDKAICTGCGKCVSTCPqailtlqsFEVPVQvecsSHDRGPVAKklcqnaCIGCG------ 222
Cdd:COG0437   68 CVKVCPTGATYKREDGIVLVDYDKCIGCRYCVAACP--------YGAPRF----NPETGVVEK------CTFCAdrldeg 129

                         90
                 ....*....|....*.
gi 697205005 223 ---LCMRSCEHGAIKI 235
Cdd:COG0437  130 llpACVEACPTGALVF 145
Nar1 COG4624
Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];
167-266 5.23e-07

Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];


Pssm-ID: 443663 [Multi-domain]  Cd Length: 450  Bit Score: 50.41  E-value: 5.23e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005 167 IVDKAICTGCGKCVSTCPQAILTLQSFEVPVQVECSSHDRgpvakklCQNACIGCGLCMRSCEHGAIKIDRFVAVVDQEI 246
Cdd:COG4624   49 SCCPRCCLCCCCCCRCCVAISCIQVRGIIIIDKRGPSIIR-------DKEKCKNCYPCVRACPVKAIKVDDGKAEIDEEK 121

                         90       100
                 ....*....|....*....|
gi 697205005 247 CKTCDtpTCLAKCPTKAIQE 266
Cdd:COG4624  122 CISCG--QCVAVCPFGAITE 139
DMSOR_beta_like cd16371
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 149-184 1.10e-06

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319893 [Multi-domain]  Cd Length: 140  Bit Score: 47.17  E-value: 1.10e-06
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 697205005 149 CVRACPFGALSMGEDGLPIVDKAICTGCGKCVSTCP 184
Cdd:cd16371   62 CVKVCPTGAITKREDGIVVVDQDKCIGCGYCVWACP 97
COG1149 COG1149
MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...
 215-266 1.20e-06

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];


Pssm-ID: 440763 [Multi-domain]  Cd Length: 68  Bit Score: 45.10  E-value: 1.20e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 697205005 215 QNACIGCGLCMRSCEHGAIKI-DRFVAVVDQEICKTCDtpTCLAKCPTKAIQE 266
Cdd:COG1149   10 EEKCIGCGLCVEVCPEGAIKLdDGGAPVVDPDLCTGCG--ACVGVCPTGAITL 60
PreA COG1146
NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and ...
 166-239 1.71e-06

NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and metabolism];


Pssm-ID: 440761 [Multi-domain]  Cd Length: 67  Bit Score: 44.70  E-value: 1.71e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 697205005 166 PIVDKAICTGCGKCVSTCPQAILTLQsfevpvqvecsshDRGPVAKKLCQNACIGCGLCMRSCEHGAIKIDRFV 239
Cdd:COG1146    3 PVIDTDKCIGCGACVEVCPVDVLELD-------------EEGKKALVINPEECIGCGACELVCPVGAITVEDDE 63
NapH COG0348
Polyferredoxin NapH [Energy production and conversion];
149-236 1.87e-06

Polyferredoxin NapH [Energy production and conversion];


Pssm-ID: 440117 [Multi-domain]  Cd Length: 263  Bit Score: 48.13  E-value: 1.87e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005 149 CVRACPFGALS--MGEDGL--PIVDKAICTGCGKCVSTCPQAIltlqsfevpvqvecsshDrgPVAKKLCQNACIGCGLC 224
Cdd:COG0348  184 CRYLCPYGAFQglLSDLSTlrVRYDRGDCIDCGLCVKVCPMGI-----------------D--IRKGEINQSECINCGRC 244

                         90
                 ....*....|..
gi 697205005 225 MRSCEHGAIKID 236
Cdd:COG0348  245 IDACPKDAIRFS 256
Nar1 COG4624
Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];
123-235 2.00e-06

Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];


Pssm-ID: 443663 [Multi-domain]  Cd Length: 450  Bit Score: 48.48  E-value: 2.00e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005 123 IHDCAAAKLIQGGPKGCKYGCIGFGNCVRACPFGALSMGEDGLPIVDKAICTGCGKCVSTCPqailtlqsfevpvqVECS 202
Cdd:COG4624   43 DDDSACSCCPRCCLCCCCCCRCCVAISCIQVRGIIIIDKRGPSIIRDKEKCKNCYPCVRACP--------------VKAI 108

                         90       100       110
                 ....*....|....*....|....*....|...
gi 697205005 203 SHDRGpvAKKLCQNACIGCGLCMRSCEHGAIKI 235
Cdd:COG4624  109 KVDDG--KAEIDEEKCISCGQCVAVCPFGAITE 139
FDH-O_like cd10560
beta subunit of formate dehydrogenase O (FDH-O) and similar proteins; This subfamily includes ...
 149-265 2.71e-06

beta subunit of formate dehydrogenase O (FDH-O) and similar proteins; This subfamily includes beta subunit of formate dehydrogenase family O (FDH-O), which is highly homologous to formate dehydrogenase N (FDH-N), a member of the DMSO reductase family. In E. coli three formate dehydrogenases are synthesized that are capable of oxidizing formate; Fdh-H, couples formate disproportionation to hydrogen and CO2, and is part of the cytoplasmically oriented formate hydrogenlyase complex, while FDH-N and FDH-O indicate their respective induction after growth with nitrate and oxygen. Little is known about FDH-O, although it shows formate oxidase activity during aerobic growth and is also synthesized during nitrate respiration, similar to FDH-N.


Pssm-ID: 319882 [Multi-domain]  Cd Length: 225  Bit Score: 47.38  E-value: 2.71e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005 149 CVRACPFGALSMGEDGLPIVDKAICTGCGKCVSTCPqailtlqsFEVPVQvecsSHDRGPVAKklcqnacigCGLCMrsc 228
Cdd:cd10560   86 CLEACPTGAIFRTEFGTVYIQPDICNGCGYCVAACP--------FGVIDR----NEETGRAHK---------CTLCY--- 141

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 697205005 229 ehgaikiDRfvavvdqeickTCD--TPTCLAKCPTKAIQ 265
Cdd:cd10560  142 -------DR-----------LKDglEPACAKACPTGSIQ 162
NapF COG1145
Ferredoxin [Energy production and conversion];
143-195 3.63e-06

Ferredoxin [Energy production and conversion];


Pssm-ID: 440760 [Multi-domain]  Cd Length: 238  Bit Score: 47.02  E-value: 3.63e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 697205005 143 CIGFGNCVRACPFGALSMGEDGLPI-VDKAICTGCGKCVSTCPQAILTLQSFEV 195
Cdd:COG1145  184 CIGCGLCVKVCPTGAIRLKDGKPQIvVDPDKCIGCGACVKVCPVGAISLEPKEI 237
COG2768 COG2768
Uncharacterized Fe-S cluster protein [Function unknown];
163-245 3.63e-06

Uncharacterized Fe-S cluster protein [Function unknown];


Pssm-ID: 442050 [Multi-domain]  Cd Length: 74  Bit Score: 43.95  E-value: 3.63e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005 163 DGLPIVDKAICTGCGKCVSTCPQAILTLQSFEVPVQVEcsshdrgpvakklcqnACIGCGLCMRSCEHGAIKIDRFVAVV 242
Cdd:COG2768    3 LGKPYVDEEKCIGCGACVKVCPVGAISIEDGKAVIDPE----------------KCIGCGACIEVCPVGAIKIEWEEDEE 66


                 ...
gi 697205005 243 DQE 245
Cdd:COG2768   67 FQE 69
SIMIBI_bact_arch cd03110
bacterial and archaeal subfamily of SIMIBI; Uncharacterized bacterial and archaeal subfamily ...
 143-210 3.76e-06

bacterial and archaeal subfamily of SIMIBI; Uncharacterized bacterial and archaeal subfamily of SIMIBI superfamily. Proteins in this superfamily contain an ATP-binding domain and use energy from hydrolysis of ATP to transfer electron or ion. The specific function of this family is unknown.


Pssm-ID: 349764 [Multi-domain]  Cd Length: 246  Bit Score: 46.99  E-value: 3.76e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 697205005 143 CIGFGNCVRACPFGALSMGEDGlPIVDKAICTGCGKCVSTCPQAILTLQSFEVPvQVECSSHDRGPVA 210
Cdd:cd03110   66 CIRCGNCERVCKFGAILEFFQK-LIVDESLCEGCGACVIICPRGAIYLKDRDTG-KIFISSSDGGPLV 131
PRK09898 PRK09898
ferredoxin-like protein;
149-235 5.69e-06

ferredoxin-like protein;


Pssm-ID: 182135 [Multi-domain]  Cd Length: 208  Bit Score: 45.98  E-value: 5.69e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005 149 CVRACPFGALSMGED-GLPIVDKAICTGCGKCVSTCPQAILTLQsfevpvqvecsshdrgPVAKKlcQNACIGCGLCMRS 227
Cdd:PRK09898 131 CMNVCPIGAITWQQKeGCITVDHKRCIGCSACTTACPWMMATVN----------------TESKK--SSKCVLCGECANA 192


                 ....*...
gi 697205005 228 CEHGAIKI 235
Cdd:PRK09898 193 CPTGALKI 200
HycB COG1142
Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];
149-235 6.11e-06

Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];


Pssm-ID: 440757 [Multi-domain]  Cd Length: 138  Bit Score: 45.03  E-value: 6.11e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005 149 CVRACPFGALSMgEDGLPIVDKAICTGCGKCVSTCP-QAILTLQSFEVPVQVECsshdrgpvakKLCQNaCIGCGLCMRS 227
Cdd:COG1142   60 CAEVCPVGAITR-DDGAVVVDEEKCIGCGLCVLACPfGAITMVGEKSRAVAVKC----------DLCGG-REGGPACVEA 127


                 ....*...
gi 697205005 228 CEHGAIKI 235
Cdd:COG1142  128 CPTGALRL 135
COG1149 COG1149
MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...
 166-240 6.36e-06

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];


Pssm-ID: 440763 [Multi-domain]  Cd Length: 68  Bit Score: 43.18  E-value: 6.36e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 697205005 166 PIVDKAICTGCGKCVSTCPQAILTLQSFEVPVQVEcsshdrgpvakklcqNACIGCGLCMRSCEHGAIKIDRFVA 240
Cdd:COG1149    6 PVIDEEKCIGCGLCVEVCPEGAIKLDDGGAPVVDP---------------DLCTGCGACVGVCPTGAITLEEREA 65
napF TIGR00402
ferredoxin-type protein NapF; The gene codes for a ferredoxin-type cytosolic protein, NapF, of ...
 143-188 6.44e-06

ferredoxin-type protein NapF; The gene codes for a ferredoxin-type cytosolic protein, NapF, of the periplasmic nitrate reductase system, as in Escherichia coli. NapF interacts with the catalytic subunit, NapA, and may be an accessory protein for NapA maturation. [Energy metabolism, Electron transport]


Pssm-ID: 273060 [Multi-domain]  Cd Length: 101  Bit Score: 44.17  E-value: 6.44e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 697205005  143 CIGFGNCVRACPFGALSMGEDGLPIV--DKAICTGCGKCVSTCPQAIL 188
Cdd:TIGR00402  36 CTRCGECASACENNILQLGQQGQPTVefDNAECDFCGKCAEACPTNAF 83
FeS pfam04060
Putative Fe-S cluster; This family includes a domain with four conserved cysteines that ...
 45-78 7.01e-06

Putative Fe-S cluster; This family includes a domain with four conserved cysteines that probably form an Fe-S redox cluster.


Pssm-ID: 461150 [Multi-domain]  Cd Length: 33  Bit Score: 42.03  E-value: 7.01e-06
                          10        20        30
                  ....*....|....*....|....*....|....
gi 697205005   45 LPKGQCGACGFAGCAKYAEAVVEDEtVPPNLCVP 78
Cdd:pfam04060   1 LPGTNCGACGYPGCRAFAEAVVAGE-AKINDCPP 33
PreA COG1146
NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and ...
 143-187 7.36e-06

NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and metabolism];


Pssm-ID: 440761 [Multi-domain]  Cd Length: 67  Bit Score: 42.77  E-value: 7.36e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 697205005 143 CIGFGNCVRACPFGALSMGEDGLP--IVDKAICTGCGKCVSTCP-QAI 187
Cdd:COG1146   10 CIGCGACVEVCPVDVLELDEEGKKalVINPEECIGCGACELVCPvGAI 57
IorA COG4231
TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and ...
 143-185 8.13e-06

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and conversion];


Pssm-ID: 443375 [Multi-domain]  Cd Length: 76  Bit Score: 43.11  E-value: 8.13e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 697205005 143 CIGFGNCVRACPFGALSMGeDGLPIVDKAICTGCGKCVSTCPQ 185
Cdd:COG4231   24 CTGCGACVKVCPADAIEEG-DGKAVIDPDLCIGCGSCVQVCPV 65
DMSOR_beta_like cd16370
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 149-233 8.59e-06

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319892 [Multi-domain]  Cd Length: 131  Bit Score: 44.19  E-value: 8.59e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005 149 CVRACPFGALSMGEDGLPIVDKAICTGCGKCVSTCP-QAILTLQSFEVPVqvecsshdrgpvakklcqnACIGCGLCMRS 227
Cdd:cd16370   61 CAEACPTGALEPRKGGGVVLDKEKCIGCGNCVKACIvGAIFWDEETNKPI-------------------ICIHCGYCARY 121


                 ....*.
gi 697205005 228 CEHGAI 233
Cdd:cd16370  122 CPHDVL 127
DMSOR_beta_like cd16373
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 147-184 8.71e-06

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319895 [Multi-domain]  Cd Length: 154  Bit Score: 44.55  E-value: 8.71e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 697205005 147 GNCVRACPFGALSM---GEDGLPIVDKAICTGCGKCVSTCP 184
Cdd:cd16373  103 GVCVEACPTEAIAIvleDDVLRPVVDEDKCVGCGLCEYVCP 143
FDH_b_like cd10562
uncharacterized subfamily of beta subunit of formate dehydrogenase; This subfamily includes ...
 140-265 8.79e-06

uncharacterized subfamily of beta subunit of formate dehydrogenase; This subfamily includes the beta-subunit of formate dehydrogenases that are as yet uncharacterized. Members of the DMSO reductase family include formate dehydrogenase N and O (FDH-N, FDH-O) and tungsten-containing formate dehydrogenase (W-FDH) and other similar proteins. FDH-N, a major component of nitrate respiration of Escherichia coli, is involved in the major anaerobic respiratory pathway in the presence of nitrate, catalyzing the oxidation of formate to carbon dioxide at the expense of nitrate reduction to nitrite. It forms a heterotrimer; the alpha-subunit (FDH-G) is the catalytic site of formate oxidation and membrane-associated, incorporating a selenocysteine (SeCys) residue and a [4Fe/4S] cluster in addition to two bis-MGD cofactors, the beta subunit (FDH-H) contains four [4Fe/4S] clusters which transfer the electrons from the alpha subunit to the gamma-subunit (FDH-I), a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. W-FDH contains a tungsten instead of molybdenum at the catalytic center. This enzyme seems to be exclusively found in organisms such as hyperthermophilic archaea that live in extreme environments. It is a heterodimer of a large and a small subunit; the large subunit harbors the W site and one [4Fe-4S] center and the small subunit, containing three [4Fe-4S] clusters, functions to transfer electrons.


Pssm-ID: 319884 [Multi-domain]  Cd Length: 161  Bit Score: 44.99  E-value: 8.79e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005 140 KYGCIGFGN--CVRACPFGALSMGEDGLPIVDKAICTGCGKCVSTCPqailtlqsFEVPvqvecSSHDRGPVAKKlcqna 217
Cdd:cd10562   67 KRQCMHCTDaaCVKVCPTGALYKTENGAVVVDEDKCIGCGYCVAACP--------FDVP-----RYDETTNKITK----- 128

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 697205005 218 cigCGLCMRSCEHGaikidrfvavvdqeicktcDTPTCLAKCPTKAIQ 265
Cdd:cd10562  129 ---CTLCFDRIENG-------------------MQPACVKTCPTGALT 154
PsrB cd10551
polysulfide reductase beta (PsrB) subunit; This family includes the beta subunit of bacterial ...
 149-184 1.02e-05

polysulfide reductase beta (PsrB) subunit; This family includes the beta subunit of bacterial polysulfide reductase (PsrABC), an integral membrane-bound enzyme responsible for quinone-coupled reduction of polysulfides, a process important in extreme environments such as deep-sea vents and hot springs. Polysulfide reductase contains three subunits: a catalytic subunit PsrA, an electron transfer PsrB subunit and the hydrophobic transmembrane PsrC subunit. PsrB belongs to the DMSO reductase superfamily that contains [4Fe-4S] clusters which transfer the electrons from the A subunit to the hydrophobic integral membrane C subunit via the B subunit. In Shewanella oneidensis, which has highly diverse anaerobic respiratory pathways, PsrABC is responsible for H2S generation as well as its regulation via respiration of sulfur species. PsrB transfers electrons from PsrC (serving as quinol oxidase) to the catalytic subunit PsrA for reduction of corresponding electron acceptors. It has been shown that T. thermophilus polysulfide reductase could be a key energy-conserving enzyme of the respiratory chain, using polysulfide as the terminal electron acceptor and pumping protons across the membrane.


Pssm-ID: 319873 [Multi-domain]  Cd Length: 185  Bit Score: 45.22  E-value: 1.02e-05
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 697205005 149 CVRACPFGALSMGEDGLPIVDKAICTGCGKCVSTCP 184
Cdd:cd10551   61 CVKVCPTGATYKREDGIVLVDYDKCIGCRYCMAACP 96
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
166-238 1.05e-05

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 46.39  E-value: 1.05e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 697205005 166 PIVDKAICTGCGKCVSTCPQAILTLQSFEVPVqvecsshdrgpVAKKLCQnaciGCGLCMRSCEHGAIKIDRF 238
Cdd:COG1148  491 AEVDPEKCTGCGRCVEVCPYGAISIDEKGVAE-----------VNPALCK----GCGTCAAACPSGAISLKGF 548
IorA COG4231
TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and ...
 167-237 1.14e-05

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and conversion];


Pssm-ID: 443375 [Multi-domain]  Cd Length: 76  Bit Score: 42.72  E-value: 1.14e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 697205005 167 IVDKAICTGCGKCVSTCPqailtlqsfevpvqVECSSHDRGPVAKKlcQNACIGCGLCMRSCEHGAIKIDR 237
Cdd:COG4231   18 VIDEDKCTGCGACVKVCP--------------ADAIEEGDGKAVID--PDLCIGCGSCVQVCPVDAIKLEK 72
IorA COG4231
TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and ...
 215-265 1.24e-05

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and conversion];


Pssm-ID: 443375 [Multi-domain]  Cd Length: 76  Bit Score: 42.34  E-value: 1.24e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 697205005 215 QNACIGCGLCMRSCEHGAIKIDRFVAVVDQEICKTCDtpTCLAKCPTKAIQ 265
Cdd:COG4231   21 EDKCTGCGACVKVCPADAIEEGDGKAVIDPDLCIGCG--SCVQVCPVDAIK 69
DMSOR_beta_like cd10550
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 149-235 1.60e-05

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319872 [Multi-domain]  Cd Length: 130  Bit Score: 43.33  E-value: 1.60e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005 149 CVRACPFGALSMGED-GLPIVDKAICTGCGKCVSTCPqailtlqsFEVPVQVEcsshDRGPVAKklCqNACIGCGLCMRS 227
Cdd:cd10550   57 CVEACPVGAISRDEEtGAVVVDEDKCIGCGMCVEACP--------FGAIRVDP----ETGKAIK--C-DLCGGDPACVKV 121


                 ....*...
gi 697205005 228 CEHGAIKI 235
Cdd:cd10550  122 CPTGALEF 129
FDH_beta_like cd16366
beta FeS subunits of formate dehydrogenase N (FDH-N) and similar proteins; This family ...
 149-234 2.12e-05

beta FeS subunits of formate dehydrogenase N (FDH-N) and similar proteins; This family contains beta FeS subunits of several dehydrogenases in the DMSO reductase superfamily, including formate dehydrogenase N (FDH-N), tungsten-containing formate dehydrogenase (W-FDH) and other similar proteins. FDH-N is a major component of nitrate respiration of Escherichia coli; it catalyzes the oxidation of formate to carbon dioxide, donating the electrons to a second substrate to a cytochrome. W-FDH contains a tungsten instead of molybdenum at the catalytic center and seems to be exclusively found in organisms such as hyperthermophilic archaea that live in extreme environments. It catalyzes the oxidation of formate to carbon dioxide, donating the electrons to a second substrate.


Pssm-ID: 319888 [Multi-domain]  Cd Length: 156  Bit Score: 43.54  E-value: 2.12e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005 149 CVRACPFGALSMGEDGLPIVDKAICTGCGKCVSTCPqailtlqsFEVPVQVEcsshDRGPVAK-KLCQNAcIGCGL---C 224
Cdd:cd16366   78 CLAACPTGAIIRTETGTVVVDPETCIGCGYCVNACP--------FDIPRFDE----ETGRVAKcTLCYDR-ISNGLqpaC 144

                         90
                 ....*....|
gi 697205005 225 MRSCEHGAIK 234
Cdd:cd16366  145 VKTCPTGALT 154
PRK13795 PRK13795
hypothetical protein; Provisional
 167-228 2.46e-05

hypothetical protein; Provisional


Pssm-ID: 237510 [Multi-domain]  Cd Length: 636  Bit Score: 45.37  E-value: 2.46e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 697205005 167 IVDKAICTGCGKCVSTCPQAILTLQSFEVPVQVECSShdrgpvakklcqnaCIGCGLCMRSC 228
Cdd:PRK13795 577 LRRAAECVGCGVCVGACPTGAIRIEEGKRKISVDEEK--------------CIHCGKCTEVC 624
PorD COG1144
Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta ...
 215-264 3.10e-05

Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit [Energy production and conversion]; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit is part of the Pathway/BioSystem: Pyruvate oxidation


Pssm-ID: 440759 [Multi-domain]  Cd Length: 84  Bit Score: 41.58  E-value: 3.10e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 697205005 215 QNACIGCGLCMRSCEHGAIKI-DRFVAVVDQEICKTCdtPTCLAKCPTKAI 264
Cdd:COG1144   29 EDKCIGCGLCWIVCPDGAIRVdDGKYYGIDYDYCKGC--GICAEVCPVKAI 77
DMSOR_beta-like cd04410
Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta ...
 167-265 3.40e-05

Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319870 [Multi-domain]  Cd Length: 136  Bit Score: 42.76  E-value: 3.40e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005 167 IVDKAICTGCGKCVSTCPQA-ILTLQSFEVPVQVECSSHDRGPVAKKLCQ----------------------------NA 217
Cdd:cd04410    2 VVDLDRCIGCGTCEVACKQEhGLRPGPDWSRIKVIEGGGLERAFLPVSCMhcedppcvkacptgaiykdedgivlideDK 81

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 697205005 218 CIGCGLCMRSCEHGAIKIDRFVAVVdqEICKTC-------DTPTCLAKCPTKAIQ 265
Cdd:cd04410   82 CIGCGSCVEACPYGAIVFDPEPGKA--VKCDLCgdrldegLEPACVKACPTGALT 134
NapF COG1145
Ferredoxin [Energy production and conversion];
9-237 4.11e-05

Ferredoxin [Energy production and conversion];


Pssm-ID: 440760 [Multi-domain]  Cd Length: 238  Bit Score: 43.94  E-value: 4.11e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005   9 IVVLVGIGTFFGVVLALADKRFAMEVNPLIHEVEDILPKGQCGACGFAGCAKYAEAVVEDETVPPNLCVPGKAAVAAKVA 88
Cdd:COG1145   20 AVVTGILGKIILNVIAGALLKAVALGGLLPIIGILAKEAFDALKDVLGILGAIVIGIGAGEIVRVGIAAADLNLKAVALV 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005  89 ELTGKKAEAAEPKYAQLKCRGTKTAAVMAARYEGIHDCAAAKLIQGGPKGCKYGCIGFGNCVRACPFGALSMGEDGLPIV 168
Cdd:COG1145  100 LLLALAVAGAAKRLIISAVKLVAGLVVAAGEVLLVIAAALAEAGLAILGAAAPVDALAISGGKKIEEELKIAIKKAKAVI 179

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 697205005 169 DKAICTGCGKCVSTCPQAILTLQSFEVPVQVEcsshdrgpvakklcQNACIGCGLCMRSCEHGAIKIDR 237
Cdd:COG1145  180 DAEKCIGCGLCVKVCPTGAIRLKDGKPQIVVD--------------PDKCIGCGACVKVCPVGAISLEP 234
PRK13795 PRK13795
hypothetical protein; Provisional
 218-260 4.53e-05

hypothetical protein; Provisional


Pssm-ID: 237510 [Multi-domain]  Cd Length: 636  Bit Score: 44.60  E-value: 4.53e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 697205005 218 CIGCGLCMRSCEHGAIKID--RFVAVVDQEICKTCDtpTCLAKCP 260
Cdd:PRK13795 583 CVGCGVCVGACPTGAIRIEegKRKISVDEEKCIHCG--KCTEVCP 625
NuoI COG1143
Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy ...
 215-265 4.89e-05

Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy production and conversion]; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440758 [Multi-domain]  Cd Length: 66  Bit Score: 40.50  E-value: 4.89e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 697205005 215 QNACIGCGLCMRSCEHGAIKID----RFVAVVDQEICKTCDtpTCLAKCPTKAIQ 265
Cdd:COG1143    1 EDKCIGCGLCVRVCPVDAITIEdgepGKVYVIDPDKCIGCG--LCVEVCPTGAIS 53
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 136-187 5.46e-05

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 44.39  E-value: 5.46e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 697205005 136 PKGCKYGCIGFgncvraCPF-----GALSMGE-DGLPIVDKAICTGCGKCVSTCP-QAI 187
Cdd:COG1245   14 PKKCNYECIKY------CPVnrtgkEAIEIDEdDGKPVISEELCIGCGICVKKCPfDAI 66
PRK12809 PRK12809
putative oxidoreductase Fe-S binding subunit; Reviewed
 173-265 5.51e-05

putative oxidoreductase Fe-S binding subunit; Reviewed


Pssm-ID: 183762 [Multi-domain]  Cd Length: 639  Bit Score: 44.25  E-value: 5.51e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005 173 CTGCGK--CVSTCPQAILTLQSFEVpvqvecsshdrgpvakKLCQNACIGCGLCMRSCEHGAIKIdrfVAVVDQEiCKTC 250
Cdd:PRK12809  56 CHHCNNapCVTACPVNALTFQSDSV----------------QLDEQKCIGCKRCAIACPFGVVEM---VDTIAQK-CDLC 115

                         90       100
                 ....*....|....*....|
gi 697205005 251 D-----TPTCLAKCPTKAIQ 265
Cdd:PRK12809 116 NqrssgTQACIEVCPTQALR 135
DMSOR_beta_like cd16370
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 143-191 6.87e-05

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319892 [Multi-domain]  Cd Length: 131  Bit Score: 41.87  E-value: 6.87e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 697205005 143 CIGFGNCVRACPFGALSMGED-GLPIvdkaICTGCGKCVSTCPQAILTLQ 191
Cdd:cd16370   85 CIGCGNCVKACIVGAIFWDEEtNKPI----ICIHCGYCARYCPHDVLAME 130
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
136-187 8.78e-05

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 43.64  E-value: 8.78e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 697205005 136 PKGCKYGCIGFgncvraCPfgALSMG--------EDGLPIVDKAICTGCGKCVSTCP-QAI 187
Cdd:PRK13409  14 PKKCNYECIKY------CP--VVRTGeetieideDDGKPVISEELCIGCGICVKKCPfDAI 66
HycB COG1142
Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];
167-265 1.00e-04

Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];


Pssm-ID: 440757 [Multi-domain]  Cd Length: 138  Bit Score: 41.57  E-value: 1.00e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005 167 IVDKAICTGCGKCVSTCPQA------------ILTLQSFEVPVQVECSSHDRGPVAK--------------KLCQNACIG 220
Cdd:COG1142    6 IADPEKCIGCRTCEAACAVAhegeegepflprIRVVRKAGVSAPVQCRHCEDAPCAEvcpvgaitrddgavVVDEEKCIG 85

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 697205005 221 CGLCMRSCEHGAIKID----RFVAVVDqEICKTCDT-PTCLAKCPTKAIQ 265
Cdd:COG1142   86 CGLCVLACPFGAITMVgeksRAVAVKC-DLCGGREGgPACVEACPTGALR 134
PhsB_like cd10553
uncharacterized beta subfamily of DMSO Reductase similar to Desulfonauticus sp PhsB; This ...
 149-187 1.49e-04

uncharacterized beta subfamily of DMSO Reductase similar to Desulfonauticus sp PhsB; This family includes beta FeS subunits of anaerobic DMSO reductase (DMSOR) superfamily that have yet to be characterized. DMSOR consists of a large, periplasmic molybdenum-containing alpha subunit as well as a small beta FeS subunit, and may also have a small gamma subunit. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and the tungsten-containing formate dehydrogenase (FDH-T). Examples of heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319875 [Multi-domain]  Cd Length: 146  Bit Score: 41.20  E-value: 1.49e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 697205005 149 CVRACPFGALSMGE-DGLPIVDKAICTGCGKCVSTCPQAI 187
Cdd:cd10553   66 CVKACPTGAMQKREkDGIVYVDQELCIGCKACIEACPWGI 105
NuoI COG1143
Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy ...
 173-238 1.69e-04

Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy production and conversion]; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440758 [Multi-domain]  Cd Length: 66  Bit Score: 38.96  E-value: 1.69e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 697205005 173 CTGCGKCVSTCPQAILTLQSFEVPVQVEcsshdrgpvakkLCQNACIGCGLCMRSCEHGAIKIDRF 238
Cdd:COG1143    4 CIGCGLCVRVCPVDAITIEDGEPGKVYV------------IDPDKCIGCGLCVEVCPTGAISMTPF 57
NarH_beta-like cd10557
beta subunit of nitrate reductase A (NarH) and similar proteins; This subfamily includes ...
 149-184 2.17e-04

beta subunit of nitrate reductase A (NarH) and similar proteins; This subfamily includes nitrate reductase A, a member of the DMSO reductase family. The respiratory nitrate reductase complex (NarGHI) from E. coli is a heterotrimer, with the catalytic subunit (NarG) with a molybdo-bis (molybdopterin guanine dinucleotide) cofactor and an [Fe-S] cluster, the electron transfer subunit (NarH) with four [Fe-S] clusters, and the integral membrane subunit (NarI) with two b-type hemes. Nitrate reductase A often forms a respiratory chain with the formate dehydrogenase via the lipid soluble quinol pool. Electron transfer from formate to nitrate is coupled to proton translocation across the cytoplasmic membrane generating proton motive force by a redox loop mechanism. Demethylmenaquinol (DMKH2) has been shown to be a good substrate for NarGHI in nitrate respiration in E. coli.


Pssm-ID: 319879 [Multi-domain]  Cd Length: 363  Bit Score: 41.96  E-value: 2.17e-04
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 697205005 149 CVRACPFGAL-SMGEDGLPIVDKAICTGCGKCVSTCP 184
Cdd:cd10557  187 CVAACPSGAIyKREEDGIVLIDQDRCRGWRMCVSACP 223
DMSOR_beta_like cd10550
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 218-265 2.37e-04

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319872 [Multi-domain]  Cd Length: 130  Bit Score: 40.25  E-value: 2.37e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 697205005 218 CIGCGLCMRSCEHGAIKIDRFVAVVdqEICKTCD-TPTCLAKCPTKAIQ 265
Cdd:cd10550   82 CIGCGMCVEACPFGAIRVDPETGKA--IKCDLCGgDPACVKVCPTGALE 128
DMSOR_beta_like cd16374
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 149-190 2.45e-04

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319896 [Multi-domain]  Cd Length: 139  Bit Score: 40.34  E-value: 2.45e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 697205005 149 CVRACPFGALSMGEDGLPIVDKAICTGCGKCVSTCPQAILTL 190
Cdd:cd16374   51 CMEVCPTGAIYRDEDGAVLVDPDKCIGCGMCAMACPFGVPRF 92
DMSOR_beta_like cd16368
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 149-192 2.69e-04

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319890 [Multi-domain]  Cd Length: 200  Bit Score: 40.87  E-value: 2.69e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 697205005 149 CVRACPFGALSMGEDGLPIVDKAICTGCGKCVSTCPQAILTLQS 192
Cdd:cd16368   99 CAKLCPFGAARKTPEGAVYIDDDLCFGGAKCRDVCPWHIPQRQA 142
PRK10882 PRK10882
hydrogenase 2 operon protein HybA;
148-184 3.72e-04

hydrogenase 2 operon protein HybA;


Pssm-ID: 236786 [Multi-domain]  Cd Length: 328  Bit Score: 41.19  E-value: 3.72e-04
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 697205005 148 NCVRACPFGALSMG-EDGLPIVDKAICTGCGKCVSTCP 184
Cdd:PRK10882 119 NCVSVCPVSALTKDpKTGIVHYDKDVCTGCRYCMVACP 156
NapH COG0348
Polyferredoxin NapH [Energy production and conversion];
143-190 3.95e-04

Polyferredoxin NapH [Energy production and conversion];


Pssm-ID: 440117 [Multi-domain]  Cd Length: 263  Bit Score: 40.82  E-value: 3.95e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 697205005 143 CIGFGNCVRACPfgalsMGEDglpIVDKAI----CTGCGKCVSTCPQAILTL 190
Cdd:COG0348  212 CIDCGLCVKVCP-----MGID---IRKGEInqseCINCGRCIDACPKDAIRF 255
NapF COG1145
Ferredoxin [Energy production and conversion];
55-265 4.43e-04

Ferredoxin [Energy production and conversion];


Pssm-ID: 440760 [Multi-domain]  Cd Length: 238  Bit Score: 40.86  E-value: 4.43e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005  55 FAGCAKYAEAVVEDETVPPNLCVPGKAAVAAKVAELTGKKAEAAEPKYAQLKCRGTKTAAVMAARYEGIHDCAAAKLIQG 134
Cdd:COG1145   30 ILNVIAGALLKAVALGGLLPIIGILAKEAFDALKDVLGILGAIVIGIGAGEIVRVGIAAADLNLKAVALVLLLALAVAGA 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005 135 GPKGCKYGCIGFGNCVRACPFGALSMGEDGLPIVDKAICTGCGKCVSTCPQAILTLQSFEVPVQVECSSHDRgpvakklc 214
Cdd:COG1145  110 AKRLIISAVKLVAGLVVAAGEVLLVIAAALAEAGLAILGAAAPVDALAISGGKKIEEELKIAIKKAKAVIDA-------- 181

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 697205005 215 qNACIGCGLCMRSCEHGAIKI--DRFVAVVDQEICKTCdtPTCLAKCPTKAIQ 265
Cdd:COG1145  182 -EKCIGCGLCVKVCPTGAIRLkdGKPQIVVDPDKCIGC--GACVKVCPVGAIS 231
NuoI TIGR01971
NADH-quinone oxidoreductase, chain I; This model represents the I subunit (one of 14: A->N) of ...
 143-194 4.66e-04

NADH-quinone oxidoreductase, chain I; This model represents the I subunit (one of 14: A->N) of the NADH-quinone oxidoreductase complex I which generally couples NADH and ubiquinone oxidation/reduction in bacteria and mammalian mitochondria, but may act on NADPH and/or plastoquinone in cyanobacteria and plant chloroplasts. This model excludes "I" subunits from the closely related F420H2 dehydrogenase and formate hydrogenlyase complexes. [Energy metabolism, Electron transport]


Pssm-ID: 273902 [Multi-domain]  Cd Length: 122  Bit Score: 39.32  E-value: 4.66e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 697205005  143 CIGFGNCVRACPFGALSM----GEDG-----LPIVDKAICTGCGKCVSTCP-QAILTLQSFE 194
Cdd:TIGR01971  45 CIGCTLCAAVCPADAIRVvpaeGEDGkrrlkFYEINFGRCIFCGLCEEACPtDAIVLTPEFE 106
PorD COG1144
Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta ...
 166-237 4.93e-04

Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit [Energy production and conversion]; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit is part of the Pathway/BioSystem: Pyruvate oxidation


Pssm-ID: 440759 [Multi-domain]  Cd Length: 84  Bit Score: 38.11  E-value: 4.93e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 697205005 166 PIVDKAICTGCGKCVSTCPQAILTLQSfEVPVQVEcsshdrgpvakklcQNACIGCGLCMRSCEHGAIKIDR 237
Cdd:COG1144   25 PVVDEDKCIGCGLCWIVCPDGAIRVDD-GKYYGID--------------YDYCKGCGICAEVCPVKAIEMVP 81
porD PRK09624
pyruvate ferredoxin oxidoreductase subunit delta; Reviewed
 136-184 5.60e-04

pyruvate ferredoxin oxidoreductase subunit delta; Reviewed


Pssm-ID: 170017 [Multi-domain]  Cd Length: 105  Bit Score: 38.47  E-value: 5.60e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 697205005 136 PKGCKYGCIGFGNCVRACPFGALSMGEDGLPIVDKAICTGCGKCVSTCP 184
Cdd:PRK09624  46 PEFNRDKCVRCYLCYIYCPEPAIYLDEEGYPVFDYDYCKGCGICANECP 94
RNAP_D cd07030
D subunit of Archaeal RNA polymerase; The D subunit of archaeal RNA polymerase (RNAP) is ...
 173-242 5.97e-04

D subunit of Archaeal RNA polymerase; The D subunit of archaeal RNA polymerase (RNAP) is involved in the assembly of RNAP subunits. RNAP is a large multi-subunit complex responsible for the synthesis of RNA. It is the principal enzyme of the transcription process, and is a final target in many regulatory pathways that control gene expression in all living cells. A single distinct RNAP complex is found in archaea, which may be responsible for the synthesis of all RNAs. The archaeal RNAP harbors homologues of all eukaryotic RNAP II subunits with two exceptions (RPB8 and RPB9). The 12 archaeal subunits are designated by letters and can be divided into three functional groups that are engaged in: (I) catalysis (A'/A", B'/B" or B); (II) assembly (L, N, D and P); and (III) auxiliary functions (F, E, H and K). The D subunit is equivalent to the RPB3 subunit of eukaryotic RNAP II. It contains two subdomains: one subdomain is similar the eukaryotic Rpb11/AC19/archaeal L subunit which is involved in dimerization, and the other is an inserted beta sheet subdomain. The assembly of the two largest archaeal RNAP subunits that provide most of the enzyme's catalytic functions depends on the presence of the archaeal D/L heterodimer.


Pssm-ID: 132908 [Multi-domain]  Cd Length: 259  Bit Score: 40.33  E-value: 5.97e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 697205005 173 CTGCGKCVSTCPQAILTLQSFEVPVQVECSshdrgpvakklcqnaCIGCGLCMRSCEHGAIKI----DRFVAVV 242
Cdd:cd07030  171 CDGCGKCVEECPRGVLELEEGKVVVEDLED---------------CSLCKLCERACDAGAIRVgwdeDRFIFEV 229
Fer4_7 pfam12838
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 143-187 6.24e-04

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 463724 [Multi-domain]  Cd Length: 51  Bit Score: 37.12  E-value: 6.24e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 697205005  143 CIGFGNCVRACPFGALSMGEDGLP------IVDKAICTGCGKCVSTCPQAI 187
Cdd:pfam12838   1 CIGCGACVAACPVGAITLDEVGEKkgtktvVIDPERCVGCGACVAVCPTGA 51
Fer4_9 pfam13187
4Fe-4S dicluster domain;
143-185 6.54e-04

4Fe-4S dicluster domain;


Pssm-ID: 463801 [Multi-domain]  Cd Length: 50  Bit Score: 36.76  E-value: 6.54e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 697205005  143 CIGFGNCVRACPFGALSMGEDGLPIV---DKAICTGCGKCVSTCPQ 185
Cdd:pfam13187   2 CTGCGACVAACPAGAIVPDLVGQTIRgdiAGLACIGCGACVDACPR 47
Fer4_10 pfam13237
4Fe-4S dicluster domain; This family includes proteins containing domains which bind to ...
 143-184 6.82e-04

4Fe-4S dicluster domain; This family includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. The structure of the domain is an alpha-antiparallel beta sandwich.


Pssm-ID: 404174 [Multi-domain]  Cd Length: 56  Bit Score: 37.23  E-value: 6.82e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 697205005  143 CIGFGNCVRACPFGALSMGEDGLPIVDKAI------CTGCGKCVSTCP 184
Cdd:pfam13237   9 CIGCGRCTAACPAGLTRVGAIVERLEGEAVrigvwkCIGCGACVEACP 56
FDH-N cd10558
The beta FeS subunit of formate dehydrogenase-N (FDH-N); This subfamily contains beta FeS ...
 140-265 7.20e-04

The beta FeS subunit of formate dehydrogenase-N (FDH-N); This subfamily contains beta FeS subunit of formate dehydrogenase-N (FDH-N), a member of the DMSO reductase family. FDH-N is involved in the major anaerobic respiratory pathway in the presence of nitrate, catalyzing the oxidation of formate to carbon dioxide at the expense of nitrate reduction to nitrite. Thus, FDH-N is a major component of nitrate respiration of Escherichia coli. This integral membrane enzyme forms a heterotrimer; the alpha-subunit (FDH-G) is the catalytic site of formate oxidation and membrane-associated, incorporating a selenocysteine (SeCys) residue and a [4Fe/4S] cluster in addition to two bis-MGD cofactors, the beta subunit (FDH-H) contains four [4Fe/4S] clusters which transfer the electrons from the alpha subunit to the gamma-subunit (FDH-I), a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups.


Pssm-ID: 319880 [Multi-domain]  Cd Length: 208  Bit Score: 39.68  E-value: 7.20e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005 140 KYGCIGFGN--CVRACP-FGALSMGEDGLPIVDKAICTGCGKCVSTCPqailtlqsFEVPVqvecSSHDRGPVAKklcqn 216
Cdd:cd10558   67 KDGCMHCADpgCLKACPsPGAIVQYANGIVDFQSDKCIGCGYCIKGCP--------FDIPR----ISKDDNKMYK----- 129

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 697205005 217 acigCGLCMrscehgaikiDRfvAVVDQEicktcdtPTCLAKCPTKAIQ 265
Cdd:cd10558  130 ----CTLCS----------DR--VSVGLE-------PACVKTCPTGALH 155
NapF_like cd10564
NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, ...
 171-265 8.70e-04

NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, the iron-sulfur subunit of periplasmic nitrate reductase. The periplasmic nitrate reductase NapABC of Escherichia coli likely functions during anaerobic growth in low-nitrate environments; napF operon expression is activated by cyclic AMP receptor protein (Crp). NapF is a subfamily of the beta subunit of DMSO reductase (DMSOR) family. DMSOR family members have a large, periplasmic molybdenum-containing alpha subunit as well as a small beta FeS subunit, and may also have a small gamma subunit. The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319886 [Multi-domain]  Cd Length: 139  Bit Score: 38.76  E-value: 8.70e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005 171 AICTGCGKCVSTCPQAILTLQSFEVPvQVECSshdrgpvakklcQNACIGCGLCMRSCEHGAIKIDRFVAV-VDQEIckt 249
Cdd:cd10564   13 DLCTRCGDCVEACPEGIIVRGDGGFP-ELDFS------------RGECTFCGACAEACPEGALDPAREAPWpLRAEI--- 76

                         90       100
                 ....*....|....*....|....*..
gi 697205005 250 cdTPTCLAK-----------CPTKAIQ 265
Cdd:cd10564   77 --GDSCLALqgvecrscqdaCPTQAIR 101
vorD PRK09623
3-methyl-2-oxobutanoate dehydrogenase subunit delta;
215-264 9.83e-04

3-methyl-2-oxobutanoate dehydrogenase subunit delta;


Pssm-ID: 170016 [Multi-domain]  Cd Length: 105  Bit Score: 38.00  E-value: 9.83e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 697205005 215 QNACIGCGLCMRSCEHGAIKI--DRFVAVvDQEICKTCDTptCLAKCPTKAI 264
Cdd:PRK09623  50 ESKCVKCYICWKFCPEPAIYIkeDGYVAI-DYDYCKGCGI--CANECPTKAI 98
vorD PRK09623
3-methyl-2-oxobutanoate dehydrogenase subunit delta;
143-194 1.03e-03

3-methyl-2-oxobutanoate dehydrogenase subunit delta;


Pssm-ID: 170016 [Multi-domain]  Cd Length: 105  Bit Score: 38.00  E-value: 1.03e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 697205005 143 CIGFGNCVRACPFGALSMGEDGLPIVDKAICTGCGKCVSTCPQAILTLQSFE 194
Cdd:PRK09623  53 CVKCYICWKFCPEPAIYIKEDGYVAIDYDYCKGCGICANECPTKAITMVKEE 104
HybA_like cd10561
the FeS subunit of hydrogenase 2; This subfamily includes the beta-subunit of hydrogenase 2 ...
 149-196 1.33e-03

the FeS subunit of hydrogenase 2; This subfamily includes the beta-subunit of hydrogenase 2 (Hyd-2), an enzyme that catalyzes the reversible oxidation of H2 to protons and electrons. Hyd-2 is membrane-associated and forms an unusual heterotetrameric [NiFe]-hydrogenase in that it lacks the typical cytochrome b membrane anchor subunit that transfers electrons to the quinone pool. The electron transfer subunit of Hyd-2 (HybA) which is predicted to contain four iron-sulfur clusters, is essential for electron transfer from Hyd-2 to menaquinone/demethylmenaquinone (MQ/DMQ) to couple hydrogen oxidation to fumarate reduction.


Pssm-ID: 319883 [Multi-domain]  Cd Length: 196  Bit Score: 38.73  E-value: 1.33e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 697205005 149 CVRACPFGALSMGEDGLPIVDKAICTGCGKCVSTCPqailtlqsFEVP 196
Cdd:cd10561   77 CVSACPVGALRKTPEGPVTYDEDKCIGCRYCMVACP--------FNIP 116
CooF_like cd10563
CooF, iron-sulfur subunit of carbon monoxide dehydrogenase; This family includes CooF, the ...
 218-265 1.38e-03

CooF, iron-sulfur subunit of carbon monoxide dehydrogenase; This family includes CooF, the iron-sulfur subunit of carbon monoxide dehydrogenase (CODH), found in anaerobic bacteria and archaea. Carbon monoxide dehydrogenase is a key enzyme for carbon monoxide (CO) metabolism, where CooF is the proposed mediator of electron transfer between CODH and the CO-induced hydrogenase, catalyzing the reaction that uses CO as a single carbon and energy source, and producing only H2 and CO2. The ion-sulfur subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons in the protein complex during reaction.


Pssm-ID: 319885 [Multi-domain]  Cd Length: 140  Bit Score: 38.01  E-value: 1.38e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 697205005 218 CIGCGLCMRSCEHGAIKIDRFVAVVDQ-EICKTCDTPTCLAKCPTKAIQ 265
Cdd:cd10563   90 CVGCWMCVMVCPYGAIRPDKERKVALKcDLCPDRETPACVEACPTGALV 138
PRK13984 PRK13984
putative oxidoreductase; Provisional
 117-190 1.39e-03

putative oxidoreductase; Provisional


Pssm-ID: 172486 [Multi-domain]  Cd Length: 604  Bit Score: 39.75  E-value: 1.39e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005 117 AARYEGIHDCAAAKliqggpkgckygCIGFGNCVRACPFGALSM-------GEDGL----PIVDKAICTGCGKCVSTCPQ 185
Cdd:PRK13984  33 AERYRGFHINDWEK------------CIGCGTCSKICPTDAITMvevpdlpQEYGKkpqrPVIDYGRCSFCALCVDICTT 100


                 ....*
gi 697205005 186 AILTL 190
Cdd:PRK13984 101 GSLKM 105
PRK14993 PRK14993
tetrathionate reductase subunit TtrB;
149-184 1.41e-03

tetrathionate reductase subunit TtrB;


Pssm-ID: 184955 [Multi-domain]  Cd Length: 244  Bit Score: 39.09  E-value: 1.41e-03
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 697205005 149 CVRACPFGALSMGEDGLPIVDKAICTGCGKCVSTCP 184
Cdd:PRK14993 108 CVPVCPVQATFQREDGIVVVDNKRCVGCAYCVQACP 143
PRK00783 PRK00783
DNA-directed RNA polymerase subunit D; Provisional
 143-184 1.88e-03

DNA-directed RNA polymerase subunit D; Provisional


Pssm-ID: 234837 [Multi-domain]  Cd Length: 263  Bit Score: 39.10  E-value: 1.88e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 697205005 143 CIGFGNCVRACPFGALSMGEDGLPIVDKAICTGCGKCVSTCP 184
Cdd:PRK00783 171 CDECEKCVEACPRGVLELKEGKLVVTDLLNCSLCKLCERACP 212
DMSOR_beta_like cd16371
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 143-190 1.89e-03

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319893 [Multi-domain]  Cd Length: 140  Bit Score: 37.54  E-value: 1.89e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 697205005 143 CIGFGNCVRACPFGALSMGEDGlPIVDKaiCTGC------GK---CVSTCPQAILTL 190
Cdd:cd16371   86 CIGCGYCVWACPYGAPQYNPET-GKMDK--CDMCvdrldeGEkpaCVAACPTRALDF 139
Nar1 COG4624
Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];
194-265 1.92e-03

Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];


Pssm-ID: 443663 [Multi-domain]  Cd Length: 450  Bit Score: 39.24  E-value: 1.92e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 697205005 194 EVPVQVECSSHDRGPVAKKLCQNACIGCGLCMRSCEHGAIKIDRFVAVVDQEICKTCDtpTCLAKCPTKAIQ 265
Cdd:COG4624   40 EHVDDDSACSCCPRCCLCCCCCCRCCVAISCIQVRGIIIIDKRGPSIIRDKEKCKNCY--PCVRACPVKAIK 109
PRK06214 PRK06214
sulfite reductase subunit alpha;
50-79 2.04e-03

sulfite reductase subunit alpha;


Pssm-ID: 235745 [Multi-domain]  Cd Length: 530  Bit Score: 39.29  E-value: 2.04e-03
                         10        20        30
                 ....*....|....*....|....*....|
gi 697205005  50 CGACGFAgCAKYAEAVVEDETVPPNLCVPG 79
Cdd:PRK06214  92 CGQCGYN-CQDYAEAIASGEEKRLNLCAPG 120
PRK00783 PRK00783
DNA-directed RNA polymerase subunit D; Provisional
 173-242 2.06e-03

DNA-directed RNA polymerase subunit D; Provisional


Pssm-ID: 234837 [Multi-domain]  Cd Length: 263  Bit Score: 38.71  E-value: 2.06e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 697205005 173 CTGCGKCVSTCPQAILTLQSFEVPV--QVECSshdrgpvakklcqnaciGCGLCMRSCEHGAIKI----DRFVAVV 242
Cdd:PRK00783 171 CDECEKCVEACPRGVLELKEGKLVVtdLLNCS-----------------LCKLCERACPGKAIRVsddeNKFIFTV 229
Fer4_7 pfam12838
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 218-263 2.10e-03

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 463724 [Multi-domain]  Cd Length: 51  Bit Score: 35.58  E-value: 2.10e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 697205005  218 CIGCGLCMRSCEHGAIKID-------RFVAVVDQEICKTCDtpTCLAKCPTKA 263
Cdd:pfam12838   1 CIGCGACVAACPVGAITLDevgekkgTKTVVIDPERCVGCG--ACVAVCPTGA 51
DMSOR_beta_like cd16367
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 143-266 2.61e-03

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319889 [Multi-domain]  Cd Length: 138  Bit Score: 37.29  E-value: 2.61e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005 143 CIGFGNCVRACP---FGALSMGEDGLPIVDKAICTGCGKCVStcpqailtlqsfevPVQVECSSHD---RGPVAKKLCQN 216
Cdd:cd16367   21 CIRCDNCEKACAdthDGHSRLDRNGLRFGNLLVPTACRHCVD--------------PVCMIGCPTGaihRDDGGEVVISD 86

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 697205005 217 ACIGCGLCMRSCEHGAIKIDRfvaVVDQEICKTCDTPTCLAKCPTKAIQE 266
Cdd:cd16367   87 ACCGCGNCASACPYGAIQMVR---AVKCDLCAGYAGPACVSACPTGAAIR 133
porD PRK09625
pyruvate flavodoxin oxidoreductase subunit delta; Reviewed
 142-194 2.61e-03

pyruvate flavodoxin oxidoreductase subunit delta; Reviewed


Pssm-ID: 236596 [Multi-domain]  Cd Length: 133  Bit Score: 37.03  E-value: 2.61e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 697205005 142 GCIGFGNCVRACPFGALSMGEDGLPIVDKAICTGCGKCVSTCPQAILTLQSFE 194
Cdd:PRK09625  60 ICINCFNCWVYCPDAAILSRDKKLKGVDYSHCKGCGVCVEVCPTNPKSLLMFE 112
PRK10194 PRK10194
ferredoxin-type protein NapF;
143-265 3.60e-03

ferredoxin-type protein NapF;


Pssm-ID: 182296 [Multi-domain]  Cd Length: 163  Bit Score: 37.31  E-value: 3.60e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005 143 CIGFGNCVRACPFGALSMGEDGLPIVD--KAICTGCGKCVSTCPQAILTLQsfevpvqvecssHDRGPVAKKLCQNACIG 220
Cdd:PRK10194  36 CTRCDACINACENNILQRGAGGYPSVNfkNNECSFCYACAQACPESLFSPR------------HTRAWDLQFTIGDACLA 103

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 697205005 221 -----CGLCMRSCEHGAIKIDRFVAVV-----DQEICKTCDtpTCLAKCPTKAIQ 265
Cdd:PRK10194 104 yqsveCRRCQDSCEPMAIIFRPTLSGIyqpqlNSQLCNGCG--ACAASCPVSAIT 156
ACS_1 cd01916
Acetyl-CoA synthase (ACS), also known as acetyl-CoA decarbonylase, is found in acetogenic and ...
 143-187 4.40e-03

Acetyl-CoA synthase (ACS), also known as acetyl-CoA decarbonylase, is found in acetogenic and methanogenic organisms and is responsible for the synthesis and breakdown of acetyl-CoA. ACS forms a heterotetramer with carbon monoxide dehydrogenase (CODH) consisting of two ACS and two CODH subunits. CODH reduces carbon dioxide to carbon monoxide and ACS then synthesizes acetyl-CoA from carbon monoxide, CoA, and a methyl group donated by another protein (CoFeSP). ACS has three structural domains, an N-terminal rossman fold domain with a helical region at its N-terminus which interacts with CODH, and two alpha + beta fold domains. A Ni-Fe-S center referred to as the A-cluster is located in the C-terminal domain. A large cavity exists between the three domains which may bind CoA.


Pssm-ID: 238897 [Multi-domain]  Cd Length: 731  Bit Score: 38.54  E-value: 4.40e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 697205005 143 CIGFGNCVRACPFG-----ALSMGEDG--LPIVDKA-ICTGCGKCVSTCPQAI 187
Cdd:cd01916  367 CTDCGWCTRACPNSlrikeAMEAAKEGdfSGLADLFdQCVGCGRCEQECPKEI 419
PRK14028 PRK14028
pyruvate ferredoxin oxidoreductase subunit gamma/delta; Provisional
 166-237 4.47e-03

pyruvate ferredoxin oxidoreductase subunit gamma/delta; Provisional


Pssm-ID: 172522 [Multi-domain]  Cd Length: 312  Bit Score: 38.05  E-value: 4.47e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 697205005 166 PIVDKAICTGCGKCVSTCPQAILTLQSFEVPvqvecsshdrGPVAKKLCQNA-------CIGCGLCMRSCEHGAIKIDR 237
Cdd:PRK14028 242 PVIDHSKCIMCRKCWLYCPDDAIIEAWREAE----------GPRGRKFRMKMidfdyqyCKGCGVCAEVCPTGAIQMVR 310
ferrodoxin_EFR1 NF038196
EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight ...
 216-265 4.84e-03

EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight conserved Cys residues in two CxxCxxCxxxCP motifs, each of which binds a 4Fe-4S cluster. The N-terminal region resembles flavodoxin domains, with some members of the family recognized by Pfam models PF12724 (Flavodoxin_5) or PF00258 (Flavodoxin_1).


Pssm-ID: 468407 [Multi-domain]  Cd Length: 243  Bit Score: 37.53  E-value: 4.84e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 697205005 216 NACIGCGLCMRSCEHGAIKIdrfvavVDQEI-----CKTCdtPTCLAKCPTKAIQ 265
Cdd:NF038196 185 DKCIGCGICAKVCPVNNIEM------EDGKPvwghnCTHC--LACIHRCPKEAIE 231
PRK12809 PRK12809
putative oxidoreductase Fe-S binding subunit; Reviewed
 149-218 5.23e-03

putative oxidoreductase Fe-S binding subunit; Reviewed


Pssm-ID: 183762 [Multi-domain]  Cd Length: 639  Bit Score: 38.08  E-value: 5.23e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005 149 CVRACPFGALSMGEDGLPIvDKAICTGCGKCVSTCPQAILTLQSfevPVQVECSSHDRGPVAKKLCQNAC 218
Cdd:PRK12809  64 CVTACPVNALTFQSDSVQL-DEQKCIGCKRCAIACPFGVVEMVD---TIAQKCDLCNQRSSGTQACIEVC 129
NarY COG1140
Nitrate reductase beta subunit [Energy production and conversion, Inorganic ion transport and ...
 149-184 5.31e-03

Nitrate reductase beta subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440755 [Multi-domain]  Cd Length: 485  Bit Score: 37.86  E-value: 5.31e-03
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 697205005 149 CVRACPFGAL-SMGEDGLPIVDKAICTGCGKCVSTCP 184
Cdd:COG1140  190 CVASCPSGAIyKREEDGIVLVDQDKCRGWRMCVSGCP 226
ferrodoxin_EFR1 NF038196
EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight ...
 143-187 5.35e-03

EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight conserved Cys residues in two CxxCxxCxxxCP motifs, each of which binds a 4Fe-4S cluster. The N-terminal region resembles flavodoxin domains, with some members of the family recognized by Pfam models PF12724 (Flavodoxin_5) or PF00258 (Flavodoxin_1).


Pssm-ID: 468407 [Multi-domain]  Cd Length: 243  Bit Score: 37.53  E-value: 5.35e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 697205005 143 CIGFGNCVRACPFGALSMgEDGLPIVDKAiCTGCGKCVSTCPQ-AI 187
Cdd:NF038196 187 CIGCGICAKVCPVNNIEM-EDGKPVWGHN-CTHCLACIHRCPKeAI 230
HycB_like cd10554
HycB, HydN and similar proteins; This family includes HycB, the FeS subunit of a ...
 212-265 6.00e-03

HycB, HydN and similar proteins; This family includes HycB, the FeS subunit of a membrane-associated formate hydrogenlyase system (FHL-1) in Escherichia coli that breaks down formate, produced during anaerobic fermentation, to H2 and CO2. FHL-1 consists of formate dehydrogenase H (FDH-H) and the hydrogenase 3 complex (Hyd-3). HycB is thought to code for the [4Fe-4S] ferredoxin subunit of hydrogenase 3, which functions as an intermediate electron carrier protein between hydrogenase 3 and formate dehydrogenase. HydN codes for the [4Fe-4S] ferredoxin subunit of FDH-H; a hydN in-frame deletion mutation causes only weak reduction in hydrogenase activity, but loss of more than 60% of FDH-H activity. This pathway is only active at low pH and high formate concentrations, and is thought to provide a detoxification/de-acidification system countering the buildup of formate during fermentation.


Pssm-ID: 319876 [Multi-domain]  Cd Length: 149  Bit Score: 36.47  E-value: 6.00e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 697205005 212 KLCQNACIGCGLCMRSCEHGAIKIDRFVAVVDQEICKT------CD-------TPTCLAKCPTKAIQ 265
Cdd:cd10554   81 QVDEERCIGCKLCVLACPFGAIEMAPTTVPGVDWERGPravavkCDlcagregGPACVEACPTKALT 147
PRK12769 PRK12769
putative oxidoreductase Fe-S binding subunit; Reviewed
 179-265 6.50e-03

putative oxidoreductase Fe-S binding subunit; Reviewed


Pssm-ID: 183733 [Multi-domain]  Cd Length: 654  Bit Score: 37.80  E-value: 6.50e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005 179 CVSTCP-QAILTLQSfevPVQVEcsshdrgpvakklcQNACIGCGLCMRSCEHGAIKI-------DRFVAVVDQeiCKTC 250
Cdd:PRK12769  64 CARSCPnGAISHVDD---SIQVN--------------QQKCIGCKSCVVACPFGTMQIvltpvaaGKVKATAHK--CDLC 124

                         90
                 ....*....|....*....
gi 697205005 251 DT----PTCLAKCPTKAIQ 265
Cdd:PRK12769 125 AGrengPACVENCPADALQ 143
SIMIBI_bact_arch cd03110
bacterial and archaeal subfamily of SIMIBI; Uncharacterized bacterial and archaeal subfamily ...
 218-266 6.88e-03

bacterial and archaeal subfamily of SIMIBI; Uncharacterized bacterial and archaeal subfamily of SIMIBI superfamily. Proteins in this superfamily contain an ATP-binding domain and use energy from hydrolysis of ATP to transfer electron or ion. The specific function of this family is unknown.


Pssm-ID: 349764 [Multi-domain]  Cd Length: 246  Bit Score: 36.98  E-value: 6.88e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 697205005 218 CIGCGLCMRSCEHGAIKIDRFVAVVDQEICKTCDtpTCLAKCPTKAIQE 266
Cdd:cd03110   66 CIRCGNCERVCKFGAILEFFQKLIVDESLCEGCG--ACVIICPRGAIYL 112
DMSOR_beta_like cd16373
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 143-264 7.77e-03

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319895 [Multi-domain]  Cd Length: 154  Bit Score: 36.08  E-value: 7.77e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697205005 143 CIGFGNCVRACPFGALSMG--EDGL-----PIVD--KAICTGCGK-CVSTCP-QAILTLQSFEVPVQVecsshdrGpVAk 211
Cdd:cd16373   16 CIRCGLCVEACPTGVIQPAglEDGLeggrtPYLDprEGPCDLCCDaCVEVCPtGALRPLDLEEQKVKM-------G-VA- 86

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 697205005 212 KLCQNACI------GCGLCMRSCEHGAIKI----DRFVAVVDQEICKTCDtpTCLAKCPT---KAI 264
Cdd:cd16373   87 VIDKDRCLawqggtDCGVCVEACPTEAIAIvledDVLRPVVDEDKCVGCG--LCEYVCPVeppKAI 150
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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