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Conserved domains on  [gi|553309268|ref|WP_023054319|]
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NAD(P)/FAD-dependent oxidoreductase [Megasphaera vaginalis (ex Srinivasan et al. 2021)]

Protein Classification

NAD(P)/FAD-dependent oxidoreductase( domain architecture ID 11457516)

NAD(P)/FAD-dependent oxidoreductase catalyzes the transfer of electrons from one molecule, the electron donor or reductant, to another molecule, the electron acceptor or oxidant

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG2509 COG2509
FAD-dependent dehydrogenase [General function prediction only];
90-530 0e+00

FAD-dependent dehydrogenase [General function prediction only];


:

Pssm-ID: 441999 [Multi-domain]  Cd Length: 466  Bit Score: 605.18  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553309268  90 GSGKLRCRPIVVGTGPAGLAAALVLAEEGYAPLVLERGYDVDSRSLHVKEFWEKGLFRSDSNVQFGEGGAGTFSDGKLTT 169
Cdd:COG2509   25 GIPSLKYDVVIVGAGPAGLFAALELAEAGLKPLVLERGKDVEERTCPVAEFWRKGKCNPESNIQFGEGGAGTFSDGKLNT 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553309268 170 RVNHL--LLPRVLDAFVEAGAPSEIRYAYNPHIGTDILRGVVRNMRKKIERLGGSVRFCACVTGMErKKDGAVQAVIVNG 247
Cdd:COG2509  105 RSKDPqgLIRYVLEIFVKFGAPEEILYAAKPHIGTDKLPKVVKNIREYIEELGGEIRFNTRVTDIL-IEDGRVKGVVTND 183

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553309268 248 TERIETDVLLLGIGHSARDTFYMLRDNDVRLTPKDFAIGVRIEHGQDWLDRTQYGSSAADLGLEPSDYALVYHGAD-RRS 326
Cdd:COG2509  184 GEEIEADAVILAPGHSARDWFEMLHRLGVKLEAKPFDIGVRVEHPQELIDRIQYGKFAGHPLLGAAEYKLVYQTKNyGRG 263

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553309268 327 CYSFCMCPGGTVVAAASEKGMVVTNGMSVYRRDSGIANSALVVNVTAADLGSaSPLAGIEFQRHYERLAYEAGGGNYFAP 406
Cdd:COG2509  264 VYTFCMCPGGFVVAEASEPGLVVVNGMSYSDRKSENANFALLVSVTPTDFPG-GPLAGIEYQRSIERLANELGGGNYKAP 342

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553309268 407 AQTVGDFL-NRNTAGLTKGPVSYKPGVVWADLHDVLPRFVTTALAEALPYFGRKIRGFDDNHVVMTGVETRTSSPVRISR 485
Cdd:COG2509  343 AQRLGDFLaGRRSTELGSVEPTYKPGVTPGDLSLVLPYRILDALREALEAFDKKIPGFASDDALLYGVETRTSSPVRIPR 422

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*
gi 553309268 486 GEDRQAlETPGLYPIGEGAGYAGGIMSAFLDGMESALQIIELYQP 530
Cdd:COG2509  423 DEDLET-NIKGLYPAGEGAGYAGGIVSAAVDGIRVAEAIAEKLGP 466
 
Name Accession Description Interval E-value
COG2509 COG2509
FAD-dependent dehydrogenase [General function prediction only];
90-530 0e+00

FAD-dependent dehydrogenase [General function prediction only];


Pssm-ID: 441999 [Multi-domain]  Cd Length: 466  Bit Score: 605.18  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553309268  90 GSGKLRCRPIVVGTGPAGLAAALVLAEEGYAPLVLERGYDVDSRSLHVKEFWEKGLFRSDSNVQFGEGGAGTFSDGKLTT 169
Cdd:COG2509   25 GIPSLKYDVVIVGAGPAGLFAALELAEAGLKPLVLERGKDVEERTCPVAEFWRKGKCNPESNIQFGEGGAGTFSDGKLNT 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553309268 170 RVNHL--LLPRVLDAFVEAGAPSEIRYAYNPHIGTDILRGVVRNMRKKIERLGGSVRFCACVTGMErKKDGAVQAVIVNG 247
Cdd:COG2509  105 RSKDPqgLIRYVLEIFVKFGAPEEILYAAKPHIGTDKLPKVVKNIREYIEELGGEIRFNTRVTDIL-IEDGRVKGVVTND 183

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553309268 248 TERIETDVLLLGIGHSARDTFYMLRDNDVRLTPKDFAIGVRIEHGQDWLDRTQYGSSAADLGLEPSDYALVYHGAD-RRS 326
Cdd:COG2509  184 GEEIEADAVILAPGHSARDWFEMLHRLGVKLEAKPFDIGVRVEHPQELIDRIQYGKFAGHPLLGAAEYKLVYQTKNyGRG 263

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553309268 327 CYSFCMCPGGTVVAAASEKGMVVTNGMSVYRRDSGIANSALVVNVTAADLGSaSPLAGIEFQRHYERLAYEAGGGNYFAP 406
Cdd:COG2509  264 VYTFCMCPGGFVVAEASEPGLVVVNGMSYSDRKSENANFALLVSVTPTDFPG-GPLAGIEYQRSIERLANELGGGNYKAP 342

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553309268 407 AQTVGDFL-NRNTAGLTKGPVSYKPGVVWADLHDVLPRFVTTALAEALPYFGRKIRGFDDNHVVMTGVETRTSSPVRISR 485
Cdd:COG2509  343 AQRLGDFLaGRRSTELGSVEPTYKPGVTPGDLSLVLPYRILDALREALEAFDKKIPGFASDDALLYGVETRTSSPVRIPR 422

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*
gi 553309268 486 GEDRQAlETPGLYPIGEGAGYAGGIMSAFLDGMESALQIIELYQP 530
Cdd:COG2509  423 DEDLET-NIKGLYPAGEGAGYAGGIVSAAVDGIRVAEAIAEKLGP 466
 
Name Accession Description Interval E-value
COG2509 COG2509
FAD-dependent dehydrogenase [General function prediction only];
90-530 0e+00

FAD-dependent dehydrogenase [General function prediction only];


Pssm-ID: 441999 [Multi-domain]  Cd Length: 466  Bit Score: 605.18  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553309268  90 GSGKLRCRPIVVGTGPAGLAAALVLAEEGYAPLVLERGYDVDSRSLHVKEFWEKGLFRSDSNVQFGEGGAGTFSDGKLTT 169
Cdd:COG2509   25 GIPSLKYDVVIVGAGPAGLFAALELAEAGLKPLVLERGKDVEERTCPVAEFWRKGKCNPESNIQFGEGGAGTFSDGKLNT 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553309268 170 RVNHL--LLPRVLDAFVEAGAPSEIRYAYNPHIGTDILRGVVRNMRKKIERLGGSVRFCACVTGMErKKDGAVQAVIVNG 247
Cdd:COG2509  105 RSKDPqgLIRYVLEIFVKFGAPEEILYAAKPHIGTDKLPKVVKNIREYIEELGGEIRFNTRVTDIL-IEDGRVKGVVTND 183

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553309268 248 TERIETDVLLLGIGHSARDTFYMLRDNDVRLTPKDFAIGVRIEHGQDWLDRTQYGSSAADLGLEPSDYALVYHGAD-RRS 326
Cdd:COG2509  184 GEEIEADAVILAPGHSARDWFEMLHRLGVKLEAKPFDIGVRVEHPQELIDRIQYGKFAGHPLLGAAEYKLVYQTKNyGRG 263

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553309268 327 CYSFCMCPGGTVVAAASEKGMVVTNGMSVYRRDSGIANSALVVNVTAADLGSaSPLAGIEFQRHYERLAYEAGGGNYFAP 406
Cdd:COG2509  264 VYTFCMCPGGFVVAEASEPGLVVVNGMSYSDRKSENANFALLVSVTPTDFPG-GPLAGIEYQRSIERLANELGGGNYKAP 342

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553309268 407 AQTVGDFL-NRNTAGLTKGPVSYKPGVVWADLHDVLPRFVTTALAEALPYFGRKIRGFDDNHVVMTGVETRTSSPVRISR 485
Cdd:COG2509  343 AQRLGDFLaGRRSTELGSVEPTYKPGVTPGDLSLVLPYRILDALREALEAFDKKIPGFASDDALLYGVETRTSSPVRIPR 422

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*
gi 553309268 486 GEDRQAlETPGLYPIGEGAGYAGGIMSAFLDGMESALQIIELYQP 530
Cdd:COG2509  423 DEDLET-NIKGLYPAGEGAGYAGGIVSAAVDGIRVAEAIAEKLGP 466
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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