MULTISPECIES: elongation factor P [Clostridia]
elongation factor P( domain architecture ID 11415475)
elongation factor P (EF-P) is an essential protein that stimulates ribosomal peptidyltransferase activity
List of domain hits
Name | Accession | Description | Interval | E-value | ||||
Efp | COG0231 | Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) [Translation, ... |
1-185 | 9.13e-115 | ||||
Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) [Translation, ribosomal structure and biogenesis]; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) is part of the Pathway/BioSystem: Translation factors : Pssm-ID: 440001 [Multi-domain] Cd Length: 186 Bit Score: 323.51 E-value: 9.13e-115
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Name | Accession | Description | Interval | E-value | ||||
Efp | COG0231 | Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) [Translation, ... |
1-185 | 9.13e-115 | ||||
Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) [Translation, ribosomal structure and biogenesis]; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) is part of the Pathway/BioSystem: Translation factors Pssm-ID: 440001 [Multi-domain] Cd Length: 186 Bit Score: 323.51 E-value: 9.13e-115
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PRK00529 | PRK00529 | elongation factor P; Validated |
1-185 | 3.69e-109 | ||||
elongation factor P; Validated Pssm-ID: 234788 [Multi-domain] Cd Length: 186 Bit Score: 309.29 E-value: 3.69e-109
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efp | TIGR00038 | translation elongation factor P; function: involved in peptide bond synthesis. stimulate ... |
2-185 | 2.18e-102 | ||||
translation elongation factor P; function: involved in peptide bond synthesis. stimulate efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (by similarity). The trusted cutoff of this model is set high enough to exclude members of TIGR02178, an EFP-like protein of certain Gammaproteobacteria. [Protein synthesis, Translation factors] Pssm-ID: 272867 [Multi-domain] Cd Length: 184 Bit Score: 292.06 E-value: 2.18e-102
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Elong-fact-P_C | pfam09285 | Elongation factor P, C-terminal; Members of this family of nucleic acid binding domains are ... |
129-184 | 1.33e-31 | ||||
Elongation factor P, C-terminal; Members of this family of nucleic acid binding domains are predominantly found in elongation factor P, where they adopt an OB-fold, with five beta-strands forming a beta-barrel in a Greek-key topology. Pssm-ID: 430503 [Multi-domain] Cd Length: 56 Bit Score: 108.62 E-value: 1.33e-31
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Elong-fact-P_C | smart00841 | Elongation factor P, C-terminal; These nucleic acid binding domains are predominantly found in ... |
129-184 | 1.76e-27 | ||||
Elongation factor P, C-terminal; These nucleic acid binding domains are predominantly found in elongation factor P, where they adopt an OB-fold, with five beta-strands forming a beta-barrel in a Greek-key topology. Pssm-ID: 214849 [Multi-domain] Cd Length: 57 Bit Score: 97.91 E-value: 1.76e-27
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S1_EF-P_repeat_2 | cd05794 | S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. ... |
129-184 | 2.30e-26 | ||||
S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with N-formylmethionyl-tRNA and puromycine in vitro. EF-P binds to both the 30S and 50S ribosomal subunits. EF-P binds near the streptomycine binding site of the 16S rRNA in the 30S subunit. EF-P interacts with domains 2 and 5 of the 23S rRNA. The L16 ribosomal protein of the 50S or its N-terminal fragment are required for EF-P mediated peptide bond synthesis, whereas L11, L15, and L7/L12 are not required in this reaction, suggesting that EF-P may function at a different ribosomal site than most other translation factors. EF-P is essential for cell viability and is required for protein synthesis. EF-P is mainly present in bacteria. The EF-P homologs in archaea and eukaryotes are the initiation factors aIF5A and eIF5A, respectively. EF-P has 3 domains (domains I, II, and III). Domains II and III are S1-like domains. This CD includes domain III (the second S1 domain of EF_P). Domains II and III of have structural homology to the eIF5A domain C, suggesting that domains II and III evolved by duplication. Pssm-ID: 240220 [Multi-domain] Cd Length: 56 Bit Score: 95.28 E-value: 2.30e-26
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Name | Accession | Description | Interval | E-value | ||||
Efp | COG0231 | Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) [Translation, ... |
1-185 | 9.13e-115 | ||||
Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) [Translation, ribosomal structure and biogenesis]; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) is part of the Pathway/BioSystem: Translation factors Pssm-ID: 440001 [Multi-domain] Cd Length: 186 Bit Score: 323.51 E-value: 9.13e-115
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PRK00529 | PRK00529 | elongation factor P; Validated |
1-185 | 3.69e-109 | ||||
elongation factor P; Validated Pssm-ID: 234788 [Multi-domain] Cd Length: 186 Bit Score: 309.29 E-value: 3.69e-109
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efp | TIGR00038 | translation elongation factor P; function: involved in peptide bond synthesis. stimulate ... |
2-185 | 2.18e-102 | ||||
translation elongation factor P; function: involved in peptide bond synthesis. stimulate efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (by similarity). The trusted cutoff of this model is set high enough to exclude members of TIGR02178, an EFP-like protein of certain Gammaproteobacteria. [Protein synthesis, Translation factors] Pssm-ID: 272867 [Multi-domain] Cd Length: 184 Bit Score: 292.06 E-value: 2.18e-102
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PRK14578 | PRK14578 | elongation factor P; Provisional |
1-184 | 5.61e-43 | ||||
elongation factor P; Provisional Pssm-ID: 173042 [Multi-domain] Cd Length: 187 Bit Score: 141.90 E-value: 5.61e-43
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PRK04542 | PRK04542 | elongation factor P; Provisional |
1-184 | 2.48e-36 | ||||
elongation factor P; Provisional Pssm-ID: 179863 [Multi-domain] Cd Length: 189 Bit Score: 124.69 E-value: 2.48e-36
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PRK12426 | PRK12426 | elongation factor P; Provisional |
1-185 | 3.69e-35 | ||||
elongation factor P; Provisional Pssm-ID: 183522 [Multi-domain] Cd Length: 185 Bit Score: 121.88 E-value: 3.69e-35
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Elong-fact-P_C | pfam09285 | Elongation factor P, C-terminal; Members of this family of nucleic acid binding domains are ... |
129-184 | 1.33e-31 | ||||
Elongation factor P, C-terminal; Members of this family of nucleic acid binding domains are predominantly found in elongation factor P, where they adopt an OB-fold, with five beta-strands forming a beta-barrel in a Greek-key topology. Pssm-ID: 430503 [Multi-domain] Cd Length: 56 Bit Score: 108.62 E-value: 1.33e-31
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Elong-fact-P_C | smart00841 | Elongation factor P, C-terminal; These nucleic acid binding domains are predominantly found in ... |
129-184 | 1.76e-27 | ||||
Elongation factor P, C-terminal; These nucleic acid binding domains are predominantly found in elongation factor P, where they adopt an OB-fold, with five beta-strands forming a beta-barrel in a Greek-key topology. Pssm-ID: 214849 [Multi-domain] Cd Length: 57 Bit Score: 97.91 E-value: 1.76e-27
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EFP_N | pfam08207 | Elongation factor P (EF-P) KOW-like domain; |
3-60 | 7.59e-27 | ||||
Elongation factor P (EF-P) KOW-like domain; Pssm-ID: 429864 [Multi-domain] Cd Length: 58 Bit Score: 96.35 E-value: 7.59e-27
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S1_EF-P_repeat_2 | cd05794 | S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. ... |
129-184 | 2.30e-26 | ||||
S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with N-formylmethionyl-tRNA and puromycine in vitro. EF-P binds to both the 30S and 50S ribosomal subunits. EF-P binds near the streptomycine binding site of the 16S rRNA in the 30S subunit. EF-P interacts with domains 2 and 5 of the 23S rRNA. The L16 ribosomal protein of the 50S or its N-terminal fragment are required for EF-P mediated peptide bond synthesis, whereas L11, L15, and L7/L12 are not required in this reaction, suggesting that EF-P may function at a different ribosomal site than most other translation factors. EF-P is essential for cell viability and is required for protein synthesis. EF-P is mainly present in bacteria. The EF-P homologs in archaea and eukaryotes are the initiation factors aIF5A and eIF5A, respectively. EF-P has 3 domains (domains I, II, and III). Domains II and III are S1-like domains. This CD includes domain III (the second S1 domain of EF_P). Domains II and III of have structural homology to the eIF5A domain C, suggesting that domains II and III evolved by duplication. Pssm-ID: 240220 [Multi-domain] Cd Length: 56 Bit Score: 95.28 E-value: 2.30e-26
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S1_EF-P_repeat_1 | cd04470 | S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. ... |
66-126 | 5.86e-25 | ||||
S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with N-formylmethionyl-tRNA and puromycine in vitro. EF-P binds to both the 30S and 50S ribosomal subunits. EF-P binds near the streptomycine binding site of the 16S rRNA in the 30S subunit. EF-P interacts with domains 2 and 5 of the 23S rRNA. The L16 ribosomal protein of the 50S or its N-terminal fragment are required for EF-P mediated peptide bond synthesis, whereas L11, L15, and L7/L12 are not required in this reaction, suggesting that EF-P may function at a different ribosomal site than most other translation factors. EF-P is essential for cell viability and is required for protein synthesis. EF-P is mainly present in bacteria. The EF-P homologs in archaea and eukaryotes are the initiation factors aIF5A and eIF5A, respectively. EF-P has 3 domains (domains I, II, and III). Domains II and III are S1-like domains. This CD includes domain II (the first S1 domain of EF_P). Domains II and III have structural homology to the eIF5A domain C, suggesting that domains II and III evolved by duplication. Pssm-ID: 239916 [Multi-domain] Cd Length: 61 Bit Score: 91.75 E-value: 5.86e-25
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EFP | pfam01132 | Elongation factor P (EF-P) OB domain; |
68-120 | 1.05e-23 | ||||
Elongation factor P (EF-P) OB domain; Pssm-ID: 460077 [Multi-domain] Cd Length: 54 Bit Score: 88.23 E-value: 1.05e-23
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eIF_5A | TIGR00037 | translation elongation factor IF5A; Recent work (2009) changed the view of eIF5A in eukaryotes ... |
5-102 | 2.03e-05 | ||||
translation elongation factor IF5A; Recent work (2009) changed the view of eIF5A in eukaryotes and aIF5A in archaea, hypusine-containing proteins, from translation initiation factor to translation elongation factor. [Protein synthesis, Translation factors] Pssm-ID: 272866 [Multi-domain] Cd Length: 130 Bit Score: 42.12 E-value: 2.03e-05
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PRK03999 | PRK03999 | translation initiation factor IF-5A; Provisional |
5-100 | 9.02e-03 | ||||
translation initiation factor IF-5A; Provisional Pssm-ID: 235193 [Multi-domain] Cd Length: 129 Bit Score: 34.89 E-value: 9.02e-03
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Blast search parameters | ||||
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