|
Name |
Accession |
Description |
Interval |
E-value |
| UvrD |
COG0210 |
Superfamily I DNA or RNA helicase [Replication, recombination and repair]; |
3-681 |
0e+00 |
|
Superfamily I DNA or RNA helicase [Replication, recombination and repair];
Pssm-ID: 439980 [Multi-domain] Cd Length: 721 Bit Score: 802.23 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 3 DALLAPLNEAQRQAVLHFEGPALVVAGAGSGKTRTVVHRVAYLVARRGVFPSEILAVTFTNKAAEEMRERLRGLVPG-AG 81
Cdd:COG0210 1 SDLLAGLNPEQRAAVEHPEGPLLVLAGAGSGKTRVLTHRIAYLIAEGGVDPEQILAVTFTNKAAREMRERIEALLGRlAR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 82 EVWVSTFHAAALRILRVYGERVGLRPGFVVYDEDDQTALLKEVLKELALSARPGPIKALLD---RAKNRGVGLKALLGEL 158
Cdd:COG0210 81 GLWVGTFHSLALRILRRHAELLGLPPNFTILDGDDQLRLIKELLKELGLDEKRFPPRELLSlisRAKNEGLTPEELAELL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 159 PEYYAglsRGRLGDVLVRYQEALKAQGALDFGDILLYALRLLEEDEEVLRLVRKRARFIHVDEYQDTSPVQYRFTRLLAG 238
Cdd:COG0210 161 AADPE---WRAAAELYEAYQERLRANNALDFDDLLLLAVRLLEENPEVLEKYQNRFRYILVDEYQDTNPAQYELLRLLAG 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 239 EEANLMAVGDPDQGIYSFRAADIKNILDFTRDYPEARVYRLEENYRSTEAILRFANAVIVKNALRLEKALRPVKRGGEPV 318
Cdd:COG0210 238 DGRNLCVVGDDDQSIYGFRGADPENILRFEKDFPDAKVIKLEQNYRSTQNILDAANAVIANNPGRLGKNLWTDNGEGEKV 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 319 RLYRAEDAREEARFVAEEIARL---GPPWDRYAVLYRTNAQSRLLEQALAGRGIPARVVGGVGFFERAEVKDLLAYARLA 395
Cdd:COG0210 318 RLYVAPDEEEEARFVADEIRELheeGVPLSDIAVLYRTNAQSRALEEALRRAGIPYRVVGGLRFYERAEIKDLLAYLRLL 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 396 LNPLDAVSLKRVLNTPPRGIGPATWARVQLLAQEKGLPPWEALKEAARTFP----RAEPLRHFVALVEELQDLV-FGPAE 470
Cdd:COG0210 398 ANPDDDVALLRILNVPRRGIGAATLERLREAAREEGISLLEALRDLGELAGlsgrAAKALRRFAELLEALRAAAeRLPLE 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 471 AFFRHLLEATDYPTYLREAYPEDAEDRLENVEELLRAAKEAED------LQDFLDRVALTAKAEEPAEAEGKVALMTLHN 544
Cdd:COG0210 478 ELLEALLDESGYEEELREEAGEEAERRLENLEELVDAAARFEErnpgasLEAFLEELALLSDLDAADEDEDAVTLMTLHA 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 545 AKGLEFPVVFLVGVEEGLLPHRNSLSTLEGLEEERRLFYVGITRAQERLYLSHAEEREVYGRREPARPSRFLEEVEEGLY 624
Cdd:COG0210 558 AKGLEFPVVFLVGLEEGLFPHQRSLDDEEELEEERRLFYVAITRARERLYLTYAASRRLWGETQDNEPSRFLDELPEELL 637
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*..
gi 504323521 625 EVYDPYRRPPSPPPHRPRPGAFRGGERVVHPRFGPGTVVAAQGDEVTVHFEGVGLKR 681
Cdd:COG0210 638 EWVRPKAEAAAAAASAAAALPASGAGAAALAAGAAAAAAAAGGGAAVAGAGLGRAAA 694
|
|
| pcrA |
TIGR01073 |
ATP-dependent DNA helicase PcrA; Designed to identify pcrA members of the uvrD/rep subfamily. ... |
5-690 |
0e+00 |
|
ATP-dependent DNA helicase PcrA; Designed to identify pcrA members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273429 [Multi-domain] Cd Length: 726 Bit Score: 665.70 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 5 LLAPLNEAQRQAVLHFEGPALVVAGAGSGKTRTVVHRVAYLVARRGVFPSEILAVTFTNKAAEEMRERLRGLV-PGAGEV 83
Cdd:TIGR01073 1 LLAHLNPEQREAVKTTEGPLLIMAGAGSGKTRVLTHRIAHLIAEKNVAPWNILAITFTNKAAREMKERVEKLLgPVAEDI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 84 WVSTFHAAALRILRVYGERVGLRPGFVVYDEDDQTALLKEVLKELALSAR---PGPIKALLDRAKNRGVGLKALLGELPE 160
Cdd:TIGR01073 81 WISTFHSMCVRILRRDIDRIGINRNFSIIDPTDQLSLMKTILKDKNLDPKkfePRSILGTISNAKNELLPPEDFAKEATN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 161 YYAGLsrgrLGDVLVRYQEALKAQGALDFGDILLYALRLLEEDEEVLRLVRKRARFIHVDEYQDTSPVQYRFTRLLAGEE 240
Cdd:TIGR01073 161 YFEKV----VAEVYQEYQKRLLRNNALDFDDLIMTTINLFQRVPDVLEYYQRKFQYIHVDEYQDTNRAQYTLVRLLASRF 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 241 ANLMAVGDPDQGIYSFRAADIKNILDFTRDYPEARVYRLEENYRSTEAILRFANAVIVKNALRLEKALRPVKRGGEPVRL 320
Cdd:TIGR01073 237 RNLCVVGDADQSIYGWRGADIQNILSFEKDYPNATTILLEQNYRSTKNILQAANEVIEHNSNRKPKNLWTENSSGDKITY 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 321 YRAEDAREEARFVAEEIARLGPPWDR----YAVLYRTNAQSRLLEQALAGRGIPARVVGGVGFFERAEVKDLLAYARLAL 396
Cdd:TIGR01073 317 YEADTERDEAQFVAGEIDKLVKNGERkygdFAILYRTNAQSRVFEETLLKANIPYKIVGGLKFYDRKEIKDILAYLRVIA 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 397 NPLDAVSLKRVLNTPPRGIGPATWARVQLLAQEKGLPPWEALKE-------AARTfprAEPLRHFVALVEELQDLV--FG 467
Cdd:TIGR01073 397 NPDDDLSLLRIINVPKRGIGASSLEKIVNYALELNISLFEAIGEideigglAAKS---ANALLAFATMIENLRQQQeyLS 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 468 PAEAfFRHLLEATDYPTYLREAYPEDAEDRLENVEELLRAAKEAED------LQDFLDRVALTA--KAEEPAEAEGKVAL 539
Cdd:TIGR01073 474 PTEL-VEEVLDKSGYREMLKAEKTEEAQSRLENLDEFLSVTKEFEDesedksLIDFLTDLALVSdlDELEETEEGGAVTL 552
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 540 MTLHNAKGLEFPVVFLVGVEEGLLPHRNSLSTLEGLEEERRLFYVGITRAQERLYLSHAEEREVYGRREPARPSRFLEEV 619
Cdd:TIGR01073 553 MTLHAAKGLEFPVVFLIGMEEGVFPHSRSLMDEKELEEERRLAYVGITRAEEELYLTHATMRTLFGRIQMNPPSRFLNEI 632
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 620 EEGLYEVYDPYRRPPSPPPHRPRP-------------------GAFRGGERVVHPRFGPGTVVAAQGD----EVTVHFEG 676
Cdd:TIGR01073 633 PAELLETASTGRRTGATDPKGPSIrqagasrpttsqptaggdtLSWAVGDRVNHKKWGIGTVVSVKGGgddqELDIAFPS 712
|
730
....*....|....
gi 504323521 677 VGLKRLSLKYAELK 690
Cdd:TIGR01073 713 IGVKRLLAAFAPIE 726
|
|
| uvrD |
PRK11773 |
DNA-dependent helicase II; Provisional |
4-691 |
0e+00 |
|
DNA-dependent helicase II; Provisional
Pssm-ID: 236976 [Multi-domain] Cd Length: 721 Bit Score: 561.80 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 4 ALLAPLNEAQRQAVLHFEGPALVVAGAGSGKTRTVVHRVAYLVARRGVFPSEILAVTFTNKAAEEMRERLRGLVP-GAGE 82
Cdd:PRK11773 5 YLLDSLNDKQREAVAAPLGNMLVLAGAGSGKTRVLVHRIAWLMQVENASPYSIMAVTFTNKAAAEMRHRIEQLLGtSQGG 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 83 VWVSTFHAAALRILRVYGERVGLRPGFVVYDEDDQTALLKEVLKELALSARPGP-------IKALLD---RAKNRGVGLK 152
Cdd:PRK11773 85 MWVGTFHGLAHRLLRAHWQDANLPQDFQILDSDDQLRLLKRLIKALNLDEKQWPprqaqwyINGQKDeglRPQHIQSYGD 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 153 ALLGELPEYYAglsrgrlgdvlvRYQEALKAQGALDFGDILLYALRLLEEDEEVLRLVRKRARFIHVDEYQDTSPVQYRF 232
Cdd:PRK11773 165 PVEQTWLKIYQ------------AYQEACDRAGLVDFAELLLRAHELWLNKPHILQHYQERFTHILVDEFQDTNAIQYAW 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 233 TRLLAGEEANLMAVGDPDQGIYSFRAADIKNILDFTRDYPEARVYRLEENYRSTEAILRFANAVIVKNALRLEKALRPVK 312
Cdd:PRK11773 233 IRLLAGDTGKVMIVGDDDQSIYGWRGAQVENIQRFLNDFPGAETIRLEQNYRSTANILKAANALIANNNGRLGKELWTDG 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 313 RGGEPVRLYRAEDAREEARFVAEEIA---RLGPPWDRYAVLYRTNAQSRLLEQALAGRGIPARVVGGVGFFERAEVKDLL 389
Cdd:PRK11773 313 GDGEPISLYCAFNELDEARFVVERIKtwqDNGGALSDCAILYRSNAQSRVLEEALLQAGIPYRIYGGMRFFERQEIKDAL 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 390 AYARLALNPLDAVSLKRVLNTPPRGIGPATWARVQLLAQEKGLPPWEALKEA--ARTFP-RA-EPLRHFVALVEELQDlv 465
Cdd:PRK11773 393 AYLRLIANRNDDAAFERVVNTPTRGIGDRTLDVVRQTARDRQLTLWQACRALlqEKVLAgRAaSALQRFIELIDALAQ-- 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 466 fgpaEAFFRHLLEATDY---PTYLREAYP----EDAEDRLENVEELLRAAK------EAED---LQDFLDRVALTAKAEE 529
Cdd:PRK11773 471 ----ETADMPLHEQTDRvikDSGLRAMYEqekgEKGQARIENLEELVTATRqfsypdEDEDltpLQAFLSHAALEAGEGQ 546
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 530 PAEAEGKVALMTLHNAKGLEFPVVFLVGVEEGLLPHRNSLSTLEGLEEERRLFYVGITRAQERLYLSHAEEREVYGRREP 609
Cdd:PRK11773 547 ADAHEDAVQLMTLHSAKGLEFPLVFIVGMEEGLFPSQMSLEEGGRLEEERRLAYVGITRAMQKLTLTYAESRRLYGKEVY 626
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 610 ARPSRFLEEV-EEGLYEV-------YDPYRRPPSPPPHRPRPGAFRGGERVVHPRFGPGTVVAAQGDE----VTVHFEGV 677
Cdd:PRK11773 627 HRPSRFIREIpEECVEEVrlratvsRPVSHQRMGTPAVEANDSGFKLGQRVRHPKFGEGTIVNFEGSGaharVQVAFQGQ 706
|
730
....*....|....
gi 504323521 678 GLKRLSLKYAELKP 691
Cdd:PRK11773 707 GIKWLVAAYAKLEA 720
|
|
| PRK10919 |
PRK10919 |
ATP-dependent DNA helicase Rep; Provisional |
9-619 |
1.00e-130 |
|
ATP-dependent DNA helicase Rep; Provisional
Pssm-ID: 182838 [Multi-domain] Cd Length: 672 Bit Score: 401.14 E-value: 1.00e-130
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 9 LNEAQRQAVLHFEGPALVVAGAGSGKTRTVVHRVAYLVARRGVFPSEILAVTFTNKAAEEMRERL---------RGLVpg 79
Cdd:PRK10919 3 LNPGQQQAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRGCGYQARHIAAVTFTNKAAREMKERVaqtlgrkeaRGLM-- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 80 agevwVSTFHAAALRILRVYGERVGLRPGFVVYDEDDQTALLKEvLKELALSARPGPIKALLDRAKNRGVGLKAllgelP 159
Cdd:PRK10919 81 -----ISTFHTLGLDIIKREYAALGMKSNFSLFDDTDQLALLKE-LTEGLIEDDKVLLQQLISTISNWKNDLKT-----P 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 160 EYYAGLSRGRLGDVLV----RYQEALKAQGALDFGDILLYALRLLEEDEEVLRLVRKRARFIHVDEYQDTSPVQYRFTRL 235
Cdd:PRK10919 150 AQAAAGAKGERDRIFAhcygLYDAHLKACNVLDFDDLILLPTLLLQRNEEVRERWQNKIRYLLVDEYQDTNTSQYELVKL 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 236 LAGEEANLMAVGDPDQGIYSFRAADIKNILDFTRDYPEARVYRLEENYRSTEAILRFANAVIVKNALRLEKALRPVKRGG 315
Cdd:PRK10919 230 LVGSRARFTVVGDDDQSIYSWRGARPQNLVLLSQDFPALQVIKLEQNYRSSGRILKAANILIANNPHVFEKRLFSELGYG 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 316 EPVRLYRAEDAREEA-RFVAEEIARL---GPPWDRYAVLYRTNAQSRLLEQALAGRGIPARVVGGVGFFERAEVKDLLAY 391
Cdd:PRK10919 310 DELKVLSANNEEHEAeRVTGELIAHHfvnKTQYKDYAILYRGNHQSRVFEKFLMQNRIPYKISGGTSFFSRPEIKDLLAY 389
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 392 ARLALNPLDAVSLKRVLNTPPRGIGPAT------WARVqllaQEKGL--PPWEALKEAARTFPRAEPLRHFVALVEELQD 463
Cdd:PRK10919 390 LRVLTNPDDDSAFLRIVNTPKREIGPATlqklgeWAMT----RNKSLftASFDMGLSQTLSGRGYESLTRFTHWLAEIQR 465
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 464 LVFGPAEAFFRHLLEATDYPTYLRE--AYPEDAEDRLENVEELLRAAKEAEDLQDFLDRVALTAKAE-----------EP 530
Cdd:PRK10919 466 LAEREPVAAVRDLIHGIDYESWLYEtsPSPKAAEMRMKNVNQLFSWMTEMLEGSELDEPMTLTQVVTrftlrdmmergES 545
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 531 AEAEGKVALMTLHNAKGLEFPVVFLVGVEEGLLPHRNSLSTlEGLEEERRLFYVGITRAQERLYLSHAEEREVYGRREPA 610
Cdd:PRK10919 546 EEELDQVQLMTLHASKGLEFPYVYLVGMEEGLLPHQSSIDE-DNIDEERRLAYVGITRAQKELTFTLCKERRQYGELVRP 624
|
....*....
gi 504323521 611 RPSRFLEEV 619
Cdd:PRK10919 625 EPSRFLLEL 633
|
|
| UvrD-helicase |
pfam00580 |
UvrD/REP helicase N-terminal domain; The Rep family helicases are composed of four structural ... |
9-272 |
1.32e-112 |
|
UvrD/REP helicase N-terminal domain; The Rep family helicases are composed of four structural domains. The Rep family function as dimers. REP helicases catalyze ATP dependent unwinding of double stranded DNA to single stranded DNA. Swiss:P23478, Swiss:P08394 have large insertions near to the carboxy-terminus relative to other members of the family.
Pssm-ID: 395462 [Multi-domain] Cd Length: 267 Bit Score: 339.99 E-value: 1.32e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 9 LNEAQRQAVLHFEGPALVVAGAGSGKTRTVVHRVAYLVARRGVFPSEILAVTFTNKAAEEMRERLRGLVPGAG--EVWVS 86
Cdd:pfam00580 1 LNPEQRKAVTHLGGPLLVLAGAGSGKTRVLTERIAYLILEGGIDPEEILAVTFTNKAAREMKERILKLLGKAElsELNIS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 87 TFHAAALRILRVYGERVGLRPGFVVYDEDDQTALLKEVLKELALS-----ARPGPIKALLDRAKNRGVGLKALLGelpeY 161
Cdd:pfam00580 81 TFHSFCLRILRKYANRIGLLPNFSILDELDQLALLKELLEKDRLNldpklLRKLELKELISKAKNRLLSPEELQQ----G 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 162 YAGLSRGRLGDVLVRYQEALKAQGALDFGDILLYALRLLEEDEEVLRLVRKRARFIHVDEYQDTSPVQYRFTRLLAGEEA 241
Cdd:pfam00580 157 AADPRDKLAAEFYQEYQERLKENNALDFDDLLLLTLELLRSDPELLEAYRERFKYILVDEFQDTNPIQYRLLKLLAGGHE 236
|
250 260 270
....*....|....*....|....*....|.
gi 504323521 242 NLMAVGDPDQGIYSFRAADIKNILDFTRDYP 272
Cdd:pfam00580 237 NLFLVGDPDQSIYGFRGADIENILKFEKDFP 267
|
|
| RecB |
COG1074 |
3#-5# helicase subunit RecB of the DNA repair enzyme RecBCD (exonuclease V) [Replication, ... |
8-619 |
7.59e-105 |
|
3#-5# helicase subunit RecB of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];
Pssm-ID: 440692 [Multi-domain] Cd Length: 866 Bit Score: 338.86 E-value: 7.59e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 8 PLNEAQRQAVLHFEGPALVVAGAGSGKTRTVVHRVAYLVARRGVFPSEILAVTFTNKAAEEMRERLR------------- 74
Cdd:COG1074 5 PWTDAQRRALDPLGGSVLVEASAGSGKTYTLVARYLRLLLERGLDPEEILVVTFTRAAAAEMRERIRerlaeaadledpd 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 75 -GLVPGA-----------GEVWVSTFHAAALRILRVYGERVGLRPGFVVyDEDDQTALLKEVLKEL-------------- 128
Cdd:COG1074 85 lEELARArrrlaralenlDRAAISTIHSFCQRLLREFAFEAGLDPNFEL-LDDAEALLLEEAVDDLlreayapldalala 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 129 ---------------------ALSARPGPIKALLDRA------KNRGVGLKALLGELPEYYAGLSRGR-------LGDVL 174
Cdd:COG1074 164 rlldafgrdddsleelllalyKLRSRPDWLEELAELDealealREALLKAKEALAALREALAAAAAPLlaallrlLAAVL 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 175 VRYQEALKAQGALDFGDILLYALRLLEED--EEVLRLVRKRARFIHVDEYQDTSPVQYR-FTRLLAGEEA---NLMAVGD 248
Cdd:COG1074 244 ARYERRKRERGLLDFDDLLHRALRLLRDEdaPWVAERLRERYRHILVDEFQDTSPLQWEiLRRLAGEALAdgrTLFLVGD 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 249 PDQGIYSFRAADIKNILDFTRDY---PEARVYRLEENYRSTEAILRFANAVIVKNALRLE-----KALRPVKRGGEP-VR 319
Cdd:COG1074 324 PKQSIYRFRGADPELFLEARRALegrVDGERLTLTTNFRSTPEVVDAVNALFAQLMGAGFgeipyEPVEALRPGAYPaVE 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 320 LY--------RAEDAREEARFVAEEIARL---GPPWD------RY---AVLYRTNAQSRLLEQALAGRGIPARVVGGVGF 379
Cdd:COG1074 404 LWplepddvsEEDAREREARAVAARIRRLlaeGTTVEgggrpvRPgdiAVLVRTRSEAAAIARALKAAGIPVAASDRLSL 483
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 380 FERAEVKDLLAYARLALNPLDAVSLKRVLNTPPRGIGPATWARvqLLAQEKGLPPWEALKEAARtfpraepLRHFVALVE 459
Cdd:COG1074 484 FESPEVRDLLALLRALLNPEDDLALAAVLRSPLFGLSDEDLAA--LAADRKGESLWEALRAYER-------LARALERLR 554
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 460 ELQDLV-FGPAEAFFRHLLEATDYPTYLreAYPEDAEDRLEN---VEELLRAAKEAE-----DLQDFLDRVALTAKAEEP 530
Cdd:COG1074 555 ALRELArRLGLAELLERLLEETGLLERL--LALPGGERRLANllhLDELLQLALEYEqtggpGLAGFLRWLERLIEDGGD 632
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 531 AEAE------GKVALMTLHNAKGLEFPVVFlvgveeglLPHRNSLSTLEGLEEERRLFYVGITRAQERLYLSHAEerevy 604
Cdd:COG1074 633 EEKRrlesdaDAVRIMTIHKSKGLEFPVVF--------LPALRERARAEELAEELRLLYVALTRARDRLVLSGAV----- 699
|
730
....*....|....*
gi 504323521 605 GRREPARPSRFLEEV 619
Cdd:COG1074 700 KKKDAEKESSWLARR 714
|
|
| DEXQc_UvrD |
cd17932 |
DEXQD-box helicase domain of UvrD; UvrD is a highly conserved helicase involved in mismatch ... |
10-283 |
5.90e-88 |
|
DEXQD-box helicase domain of UvrD; UvrD is a highly conserved helicase involved in mismatch repair, nucleotide excision repair, and recombinational repair. It plays a critical role in maintaining genomic stability and facilitating DNA lesion repair in many prokaryotic species including Helicobacter pylori and Escherichia coli. UvrD is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350690 [Multi-domain] Cd Length: 189 Bit Score: 273.24 E-value: 5.90e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 10 NEAQRQAVLHFEGPALVVAGAGSGKTRTVVHRVAYLVARRGVFPSEILAVTFTNKAAEEMRERLRGLVPG--AGEVWVST 87
Cdd:cd17932 1 NPEQREAVTHPDGPLLVLAGAGSGKTRVLTHRIAYLILEGGVPPERILAVTFTNKAAKEMRERLRKLLGEqlASGVWIGT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 88 FHAAALRILRVYGervglrpgfvvydeddqtallkevlkelalsarpgpikalldraknrgvglkallgelpeyyaglsr 167
Cdd:cd17932 81 FHSFALRILRRYG------------------------------------------------------------------- 93
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 168 grlgdvlvryqealkaqgalDFGDILLYALRLLEEDEEVLRLVRKRARFIHVDEYQDTSPVQYRFTRLLAGEEANLMAVG 247
Cdd:cd17932 94 --------------------DFDDLLLYALELLEENPDVREKLQSRFRYILVDEYQDTNPLQYELLKLLAGDGKNLFVVG 153
|
250 260 270
....*....|....*....|....*....|....*.
gi 504323521 248 DPDQGIYSFRAADIKNILDFTRDYPEARVYRLEENY 283
Cdd:cd17932 154 DDDQSIYGFRGADPENILDFEKDFPDAKVIKLEENY 189
|
|
| UvrD_C |
pfam13361 |
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety ... |
277-600 |
8.99e-78 |
|
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety of helicase enzymes. This domain has a AAA-like structural fold.
Pssm-ID: 433145 [Multi-domain] Cd Length: 377 Bit Score: 253.48 E-value: 8.99e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 277 YRLEENYRSTEAILRFANAVIVKNALR----LEKALRPVKRGGEPVRLYRAEDAREEARFVAEEIARL---GPPWDRYAV 349
Cdd:pfam13361 1 IHLEINYRSTKNLLKAANEFINNNFGRatiyPKKILAETVEDGEKIKIIEAETEEEEAEWIALEIKKLvarDEKYNDIAV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 350 LYRTNAQSRLLEQALAGRGIPARVVGGVGFFERAEVKDLLAYARLALNPLDAVSLKRVLNTPPRGIGPATWARVQLLaQE 429
Cdd:pfam13361 81 LTRSNSDADLIEEALKKLGIPYFVVGQTKFFRREEIKDILAYLRLIANKHDSISLKRILNGPKRGIGNATLERIREY-KK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 430 KGLPPWEALKEAART----FPRAEPLRHFVALVEELQDLVFGPAEA----------------FFRHLLEAT--------- 480
Cdd:pfam13361 160 RGLRLSDFINPDTLTygdpFVIALEQDNIVVFDVETTGLDTTEDEIiqiaaiklnkkgvvieSFERFLRLKkpvgdslqv 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 481 -DYPTYLREAYPEDAE-------DRLENVEELLRAAKEAED----------LQDFLDRVALTAKAEEPAEAEGKVALMTL 542
Cdd:pfam13361 240 hGFSDEFLQENGETPAealrdflEKLENLRELYSILREYDDieetpepedaLRNFLEIATLSNSELEGSDIKERIPIMTI 319
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 504323521 543 HNAKGLEFPVVFLVGVEEGLLPHRNSLSTLEGLEEERRLFYVGITRAQERLYLSHAEE 600
Cdd:pfam13361 320 HQAKGLEFDTVFLAGLEEGIFPSYRSIKDEGNLEEERRLFYVAITRAKKRLYISYSKS 377
|
|
| recB |
TIGR00609 |
exodeoxyribonuclease V, beta subunit; The RecBCD holoenzyme is a multifunctional nuclease with ... |
20-595 |
4.79e-36 |
|
exodeoxyribonuclease V, beta subunit; The RecBCD holoenzyme is a multifunctional nuclease with potent ATP-dependent exodeoxyribonuclease activity. Ejection of RecD, as occurs at chi recombinational hotspots, cripples exonuclease activity in favor of recombinagenic helicase activity. All proteins in this family for which functions are known are DNA-DNA helicases that are used as part of an exonuclease-helicase complex (made up of RecBCD homologs) that function to generate substrates for the initiation of recombination and recombinational repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273172 [Multi-domain] Cd Length: 1087 Bit Score: 146.03 E-value: 4.79e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 20 FEGPALVVAGAGSGKTRTVVHRVAYLVARRGVF-PSEILAVTFTNKAAEEMRERLRGLVPGA------------------ 80
Cdd:TIGR00609 8 LNGTFLIEASAGTGKTFTIAQLYLRLLLEGGPLtVEEILVVTFTNAATEELKTRIRGRIHQAlralkaaltsqelpeplk 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 81 ----------------------GEVWVSTFHAAALRILRVYG-------------------------------ERVGLRP 107
Cdd:TIGR00609 88 eaiqdekvkqaitrlrnalatmDEAAIYTIHGFCQRMLEQHAfesdeifdveliedeslllaeitkdfwrrnfYNLPFDI 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 108 GFVVYD-----EDDQTALLKEVLKELALSARPGPIK---------------ALLDRAKNRGVGLKALLGELPEYYAGLSR 167
Cdd:TIGR00609 168 AQIVLKtkkspQAVLTQILADLLLQSYLAFPSPPLDleqlikwheqiykdlDKLDHAVFEEIDKLNAERNNLFCLKDRVF 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 168 GRLGDVLVRYQEALKAQ-GALDFGDILLYALRLL--EEDEEVLRLVRKRARFIHVDEYQDTSPVQYR-FTRL-LAGEEAN 242
Cdd:TIGR00609 248 LTLLKEVQEELKKEKKRrREIGFDDLLSRLETALksAEGEKLAQAIREQYPIALIDEFQDTDPQQYRiFSKLfIAQKETS 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 243 LMAVGDPDQGIYSFRAADIknildFTrdYPEARV-----YRLEENYRSTEAIL--------------RFANAVIVKNALR 303
Cdd:TIGR00609 328 LFLIGDPKQAIYSFRGADI-----FT--YLQAKSkadarYTLGTNWRSTPALVgslnklfslisnpfLEKPIFIPVLAHQ 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 304 LEKALRPVKRGGEP-----------------------------VRLYRAEDAREEARFVAEEIARLGPPWDrYAVLYRTN 354
Cdd:TIGR00609 401 KNSKGSFVINGQEQppihffttevesegvddyrqtiaqkcareIALWLASAALGLANFIATFGGRPLRAGD-IAVLVRGR 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 355 AQSRLLEQALAGRGIPARVVGG-VGFFERAEVKDLLAYARLALNPLDAVSLKRVLNTPPRGIgpaTWARVQLLAQEKGLp 433
Cdd:TIGR00609 480 KEANQIRKALKKAQIPSVYLSDkSSVFATEEAQELLALLEALLEPENEGTLRAALASSIFGL---SALELETLNQDEIT- 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 434 pWEalkeaartfpraeplrHFVALVEELQDLV--FGPAEAFFRHLLEATDYPTYLREAypeDAEDRLENVE---ELLRAA 508
Cdd:TIGR00609 556 -WE----------------RVVEKFREYHDIWrkIGVLAMFQRLMLEKGIGERLLSQP---GGERILTNLLhlaELLQEA 615
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 509 KEAED-----LQDFLDRVALTAKAEEPAEA----EGKVALMTLHNAKGLEFPVVFL----------------------VG 557
Cdd:TIGR00609 616 AHQERnklslLRWLEDQISNEEEEEEEIIRlesdAELVKIVTIHKSKGLEYPIVFLpfitdakksnfaslhdqhsheyQL 695
|
730 740 750
....*....|....*....|....*....|....*...
gi 504323521 558 VEEGLLPHRNSLSTLEGLEEERRLFYVGITRAQERLYL 595
Cdd:TIGR00609 696 YDFNQSEENQKLARVERLAEDLRLLYVALTRAKKQLFI 733
|
|
| helD |
PRK11054 |
DNA helicase IV; Provisional |
8-314 |
5.85e-35 |
|
DNA helicase IV; Provisional
Pssm-ID: 182930 [Multi-domain] Cd Length: 684 Bit Score: 141.24 E-value: 5.85e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 8 PLNEAQRQAVLHFEGPALVVAGAGSGKTRTVVHRVAYLVARRGVFPSEILAVTFTNKAAEEMRERLRGLVpGAGEVWVST 87
Cdd:PRK11054 196 PLNPSQARAVVNGEDSLLVLAGAGSGKTSVLVARAGWLLARGQAQPEQILLLAFGRQAAEEMDERIRERL-GTEDITART 274
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 88 FHAAALRILR-VYGERVGLRPgfVVYDEDDQTALLKEVLK----ELALSA---RPGPIKAL------------------L 141
Cdd:PRK11054 275 FHALALHIIQqGSKKVPVISK--LENDSKARHALLIAEWRkqcsEKKAQAkgwRQWLTEELqwdvpegnfwddeklqrrL 352
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 142 DRAKNRGVGL--------KALLGELPEYYAGL--SRGRLGDVLVR-YQEALKAQGALDFGDILLYALRLLEEDEEVLRLv 210
Cdd:PRK11054 353 ASRLERWVSLmrmhggsqAEMIAQAPEEVRDLfqKRLKLMAPLLKaWKKALKAENAVDFSGLIHQAVNYLEKGRFISPW- 431
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 211 rkraRFIHVDEYQDTSPVQyrfTRLLAG-----EEANLMAVGDPDQGIYSFRAADIKNILDFTRDYPEARVYRLEENYRS 285
Cdd:PRK11054 432 ----KHILVDEFQDISPQR---AALLAAlrkqnSQTTLFAVGDDWQAIYRFSGADLSLTTAFHERFGEGDRCHLDTTYRF 504
|
330 340
....*....|....*....|....*....
gi 504323521 286 TEAILRFANAVIVKNALRLEKALRPVKRG 314
Cdd:PRK11054 505 NSRIGEVANRFIQQNPHQLKKPLNSLTKG 533
|
|
| AddB |
COG3857 |
ATP-dependent helicase/DNAse subunit B [Replication, recombination and repair]; |
25-626 |
6.20e-30 |
|
ATP-dependent helicase/DNAse subunit B [Replication, recombination and repair];
Pssm-ID: 443066 [Multi-domain] Cd Length: 1019 Bit Score: 126.78 E-value: 6.20e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 25 LVVAGAGSGKTRTVVHRVAYLVARRgvfpSEILAVTFTNKAAEEMRERLRGL-VPGAGEVWVSTFHAAALRILRVYGerv 103
Cdd:COG3857 2 FILGRAGSGKTTYLLEEIKEELKEG----KPIILLVPEQMTFQAERALLKRLgLGGSIRAQVLSFSRLAWRVLQETG--- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 104 glRPGFVVYDEDDQTALLKEVLKELA--------LSARPGPIKALLDRA---KNRGVG---LKALLGELPEYYAGLSRgr 169
Cdd:COG3857 75 --GATRPLLSDAGKRMLLRKILEEHKdelkvfarAADKPGFIEQLAELItelKRYGITpedLEEAAELLKEKLRDLAL-- 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 170 lgdVLVRYQEALKAQGaLDFGDILLYALRLLEEDEEVlrlvrkRARFIHVDEYQDTSPVQYRFTRLLA--GEEANLMAVG 247
Cdd:COG3857 151 ---IYEAYEEKLAGRY-IDSEDLLRLLAEKLEKSEFL------EGAEIYIDGFTDFTPQELELLEALLkkAKEVTITLTL 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 248 DPDQGIYSFRAADIKNILdftrdYPEARVYRLEENYRSTEAILRfanavivknalrLEKAL--RPVKRGGEPVRLYRAED 325
Cdd:COG3857 221 DPDELDLFSATGETYERL-----LELAKENGVEVEFKKSPELAH------------LERNLfaYPPEEEPEGIEIIEAAN 283
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 326 AREEARFVAEEIARL----GPPWDRYAVLYR-TNAQSRLLEQALAGRGIPARVVGGVGFFERAEVKDLLAYARLALNPLD 400
Cdd:COG3857 284 RRAEVEAVAREIRRLvreeGYRYRDIAVVVRdLEAYAPLIERVFAEYGIPYFIDEKRPLSHHPLVELILSLLELVRSNFR 363
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 401 AVSLKRVLNTPP-RGIGPATWARVQLLAQEKGLPPWEALKEA-ARTFPRAEPLRHFVALVEELQDLVFGPAEAF------ 472
Cdd:COG3857 364 YEDVFRLLKTGLlRPLSREEIDRLENYVLAYGIRGRRWLERYlEEEEELTDEEEEDLERLNELRDRLLEPLLPLrerlkk 443
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 473 ----------FRHLLEATDYPTYLREAYPEDAEDRLENVEELLRA---------------AKEAEDLQDF---LDRVALT 524
Cdd:COG3857 444 aktvrewaeaLYEFLEELGVPEKLEEWREAEEAGDLEEAREHEQAwnalielldelvevlGDEKLSLEEFlriLESGLEE 523
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 525 AKAEEPAEAEGKVALMTLHNAKGLEFPVVFLVGVEEGLLP---HRNSL------------------STLEGLEEERRLFY 583
Cdd:COG3857 524 LTFGLIPPSLDQVQVGGLDRARGLDFKAVFVLGLNEGVFParpREDGLlsdeererlnelglelppTSRERLLEERFLFY 603
|
650 660 670 680
....*....|....*....|....*....|....*....|...
gi 504323521 584 VGITRAQERLYLSHAEEREvygRREPARPSRFLEEVEEGLYEV 626
Cdd:COG3857 604 RALTRASERLYLSYPLADE---EGKALLPSPLIDRLRELFPEL 643
|
|
| SF1_C_UvrD |
cd18807 |
C-terminal helicase domain of UvrD family helicases; UvrD is a highly conserved helicase ... |
285-596 |
2.11e-28 |
|
C-terminal helicase domain of UvrD family helicases; UvrD is a highly conserved helicase involved in mismatch repair, nucleotide excision repair, and recombinational repair. It plays a critical role in maintaining genomic stability and facilitating DNA lesion repair in many prokaryotic species including Helicobacter pylori and Escherichia coli. This family also includes ATP-dependent helicase/nuclease AddA and helicase/nuclease RecBCD subunit RecB, among others. UvrD family helicases are DEAD-like helicases belonging to superfamily (SF)1, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF2 helicases, SF1 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350194 [Multi-domain] Cd Length: 150 Bit Score: 111.17 E-value: 2.11e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 285 STEAILRFANAVIVKNALRLEKALRPVKRGGEPVRLYRAEDAREEARFVAEEIARLGP----PWDRYAVLYRTNAQSRLL 360
Cdd:cd18807 1 STKNILDAANSLIKQNKNRPKKPLKAGNKSGGPVELLLAKDEADEAKAIADEIKRLIEsgpvQYSDIAILVRTNRQARVI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 361 EQALagrgiparvvggvgfferaevkdllayarlalnpldavslkrvlntpprgigpatwarvqllaqekglppwealke 440
Cdd:cd18807 81 EEAL---------------------------------------------------------------------------- 84
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 441 aartfpraeplrhfvalveelqdlvfgpaeaffrhlleatdyptylreaypedaedrlenveellraakeaedlqdfldr 520
Cdd:cd18807 --------------------------------------------------------------------------------
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 521 valtakaeepaeaegKVALMTLHNAKGLEFPVVFLVGVEEGLLPH----RNSLSTLEGLEEERRLFYVGITRAQERLYLS 596
Cdd:cd18807 85 ---------------RVTLMTIHASKGLEFPVVFIVGLGEGFIPSdasyHAAKEDEERLEEERRLLYVALTRAKKELYLV 149
|
|
| addA_alphas |
TIGR02784 |
double-strand break repair helicase AddA, alphaproteobacterial type; AddAB, also called RexAB, ... |
11-593 |
4.24e-26 |
|
double-strand break repair helicase AddA, alphaproteobacterial type; AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the alphaproteobacteria (as modeled here) and the Firmicutes, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 274298 [Multi-domain] Cd Length: 1135 Bit Score: 114.78 E-value: 4.24e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 11 EAQRQAVlHFEGPALVVAGAGSGKTRTVVHRVAYLVARrGVFPSEILAVTFTNKAAEEM-------------------RE 71
Cdd:TIGR02784 1 ARQAQAA-DPAASAWVSANAGSGKTHVLTQRVIRLLLA-GTEPSKILCLTYTKAAAAEMqnrvfkrlgewavlddadlRA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 72 RLRGLVPGA--------------------GEVWVSTFHAAALRILRVYGERVGLRPGFVVYDEDDQTALLKEVLKELAL- 130
Cdd:TIGR02784 79 RLEALEGKRpdaaklaearrlfaraletpGGLKIQTIHAFCEALLHQFPLEANVAGHFSVIDDRAAATLLEEARRALLAg 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 131 -------------------------------SARPGPIKALLDRAKNRG--VGLKALLG--------------------- 156
Cdd:TIGR02784 159 paapddaladalatvleaagetgleallaeiVARRDALMAFLDEAGGEGaeARLRRALGlapgdtaedlleavwplpglp 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 157 -------------------------------------------------------------------ELPE--------- 160
Cdd:TIGR02784 239 rlalaliaallksgggskdaaaalsqlreaaaepdpvarldlllgafltskgepksasfvikkaiqkSLPDlaealedaa 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 161 ---------------YYAGLSRGRLGDVLVRYQEALKAQ-GALDFGDILLYALRLLEEDEE---VLRLVRKRARFIHVDE 221
Cdd:TIGR02784 319 srvealrerlralrmAQRTLAALRLAARLLQRYARLKKArGLLDFNDLIERTVALLARPGAgawVHYKLDRGIDHILVDE 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 222 YQDTSPVQYRFTRLLA-----GEEA------NLMAVGDPDQGIYSFRAADIKNILDfTRDYPEARV---------YRLEE 281
Cdd:TIGR02784 399 AQDTSPEQWDIIQALAeeffsGEGArsgverTIFAVGDEKQSIYSFQGADPERFAE-ERREFSRKVravgrkfedLSLNY 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 282 NYRSTEAILRFANAVIVKNALRL------EKALRPVKRGGEPVR-----LYRAEDAREE-------------------AR 331
Cdd:TIGR02784 478 SFRSTPDVLAAVDLVFADPENARglsadsDAPVHEAFRDDLPGRvdlwdLISKEEGEEPedwtdpvdelgerapevrlAE 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 332 FVAEEIA-------------RLGPPWDRYAVLYRTNAQSRLLEQALAGRGIPARVVGGVGFFERAEVKDLLAYARLALNP 398
Cdd:TIGR02784 558 RIAAEIRawldrgtpipgrgRAVRPGDILVLVRKRDAFFSALIRALKRRGIPVAGADRLKLTSHIAVKDLMALGRFVLQP 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 399 LDAVSLKRVLNTPPRGIGPatwARV-QLLAQEKGLPPWEALKEAARTFPRA-EPLRHFVALVEELQdlVFgpaeAFFRHL 476
Cdd:TIGR02784 638 EDDLSLAALLKSPLFGLDE---DDLfRLAAGRSGGSLWAALRRREAEFAATlAVLRDWLSLADFLT--PF----EFYARL 708
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 477 LEATDYPTYLREAYPEDAEDRLenvEELLRAAKEAE-----DLQDFLD--RVALTAKAEEPAEAEGKVALMTLHNAKGLE 549
Cdd:TIGR02784 709 LGRDGGRRKLLARLGAEAEDIL---DEFLSQALAYErtglpGLQAFLSwlEADDPEIKREMDQARDEVRVMTVHGAKGLE 785
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 504323521 550 FPVVFLV-------------------GVEEGLLPHRNSLSTLEGL-------------EEERRLFYVGITRAQERL 593
Cdd:TIGR02784 786 APVVFLVdtgskpfasqraplllatgGSGGKAPLWRPASAFDPSLsaaarerlkeraeDEYRRLLYVAMTRAEDRL 861
|
|
| PRK13909 |
PRK13909 |
RecB-like helicase; |
28-555 |
1.86e-24 |
|
RecB-like helicase;
Pssm-ID: 237554 [Multi-domain] Cd Length: 910 Bit Score: 109.29 E-value: 1.86e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 28 AGAGSGKTRTVVHRVAYLVARrGVFPSEILAVTFTNKAAEEMRER----------------LRGLVPGAG---------- 81
Cdd:PRK13909 5 ASAGSGKTFALSVRFLALLFK-GANPSEILALTFTKKAANEMKERiidtllnlekekeeseLNELEEKLGlskeellnkr 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 82 ----------EVWVSTFHAAALRILRVYGERVGLRPGFVVyDEDDQTALLKEVLKEL----------------------- 128
Cdd:PRK13909 84 dkvyqeflnsELKISTIDAFFQKILRKFCLNLGLSPDFSI-KEDTKEELNEKFLSALskeellellafikqceskknnsf 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 129 ------------------------------------ALSARPGPIKALLDRAKN-------------------------- 146
Cdd:PRK13909 163 felleklyeknnelklfekaknpiefdeekfleelrSLKQQIQSIETASKNAKKafkkedfeellnssktwlekeseyry 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 147 ----RGVGLKALLGELPE----YYAGLSR---GRLGDVLVRYQEAL----KAQGALDFGDILLYALRLLEEDE---EVL- 207
Cdd:PRK13909 243 fkklYNEELDAEFEELKNalkrYYDAKENyklSKLFKLLQLYKEAKnelnKKKNALDFDDISKKVYELLGEEEidkDFLy 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 208 -RLvrkRARFIH--VDEYQDTSPVQYRFTR-----LLAGEEAN----LMAVGDPDQGIYSFRAADiKNILDF-TRDYPEA 274
Cdd:PRK13909 323 fRL---DSKISHilIDEFQDTSVLQYKILLplideIKSGEGQKkfrsFFYVGDVKQSIYRFRGGK-KELFDKvSKDFKQK 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 275 rVYRLEENYRSTEAILRFANAVIVKNALRLEKALRPVKRGGEPVRLYRAEDAREE-ARFVAEEIARL---GPPWDRYAVL 350
Cdd:PRK13909 399 -VDNLDTNYRSAPLIVDFVNEVFKKKYKNYKTQYAEQHKSGGYVEVVEVADESEElLEQLLQEIQFLlekGIDPDDIAIL 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 351 YRTNAQSRLLEQALAGR-GIPARVVGGVGFFERAEVKDLLAYARLAL--NPLDAVSLKRVLNTPPRgigpatwarvqlla 427
Cdd:PRK13909 478 CWTNDDALEIKEFLQEQfGIKAVTESSAKLINQPEVKALIEALKYCLfgEEIYKHNVLKLLGKEPD-------------- 543
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 428 qekglppwealkeaartfpraePLRHFVALVEELQDLVFGPAEAFfrhlleatdyptylreaypeDAEDrlENVEELLRA 507
Cdd:PRK13909 544 ----------------------KIPSFLPKEESVAEFVKKLIEEL--------------------KLYD--ENLLKFLEL 579
|
650 660 670 680
....*....|....*....|....*....|....*....|....*...
gi 504323521 508 AKEAEDLQDFLDRVALTAKAEEPAEAEGkVALMTLHNAKGLEFPVVFL 555
Cdd:PRK13909 580 ASGYEDIEEFLFKLEPCDKEIASEESKG-VQIMTVHKSKGLEFEHVIV 626
|
|
| HelD |
COG3973 |
DNA helicase IV [Replication, recombination and repair]; |
24-376 |
7.63e-20 |
|
DNA helicase IV [Replication, recombination and repair];
Pssm-ID: 443173 [Multi-domain] Cd Length: 699 Bit Score: 94.16 E-value: 7.63e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 24 ALVVAG-AGSGKTrTVV-HRVAYLV-------ARRGVF----------------PS----EILAVTFTN----------- 63
Cdd:COG3973 207 VLVVQGgAGSGKT-AVAlHRAAYLLythrerlERGGVLivgpnrlfldyisqvlPSlgeeGVVQTTFGDlvpellgveat 285
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 64 ----------KAAEEMRERLR-------------GLVPGAGEVWVS--------------TFHAAAL-----RILRVYGE 101
Cdd:COG3973 286 aeedpevarlKGSLRMAEVLDravrdlerevpfeDIRVEGGEVILSaeeiaeafyrarrsLPHNKRRerlreRLLDALKD 365
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 102 RVGLRPGfvVYDEDDQTALLKEVlkelalsARPGPIKALLDRAkNRGVGLKALLGEL---PEYYAGLSRG---RLGDVLV 175
Cdd:COG3973 366 QLAAELG--KLWDEERDELRREL-------RRSKPVRAALNRL-WPFLDPAELYRDLfsdPELLARAAGWlspEERALLL 435
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 176 RYQEALKAqGALDFGDI--LLYALRLLEEDEEvlrlvRKRARFIHVDEYQDTSPVQYRFTRLLaGEEANLMAVGDPDQGI 253
Cdd:COG3973 436 RPTRELKK-GRWTVADValLDELAELLGGPDR-----TWTYGHVVVDEAQDLSPMQWRVLKRR-FPSASFTIVGDLAQAI 508
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 254 YSFRAADIKNILDFTRDYPEARVYRLEENYRSTEAILRFANAVIVKNALRLEKAlRPVKRGGEPVRLYRAEDAREEARFV 333
Cdd:COG3973 509 HPYRGAESWEEVLEPLGGDRARLVELTKSYRSTAEIMEFANRVLRAAGPDLPPP-ESVRRHGEPPRVVRVPSEAELAAAV 587
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 504323521 334 AEEIAR-LGPPWDRYAVLYRTNAQSRLLEQALAgRGIPARVVGG 376
Cdd:COG3973 588 VEAVRElLAEGEGTIAVICKTAREAEALYAALK-AGLPVTLIDD 630
|
|
| COG3972 |
COG3972 |
Superfamily I DNA and RNA helicases [Replication, recombination and repair]; |
9-600 |
1.44e-17 |
|
Superfamily I DNA and RNA helicases [Replication, recombination and repair];
Pssm-ID: 443172 [Multi-domain] Cd Length: 565 Bit Score: 86.42 E-value: 1.44e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 9 LNEAQRQAVLHF-EGPALVVAGAGSGKTRTVVHRVAYLVARrgvFPSEILAVTFTNKA-AEEMRERL--RGLVPGAGEVW 84
Cdd:COG3972 160 LDLQQERIARSIpDGPQRIRGVAGSGKTVLLAAKAAYLALK---HPGWRILVTCFNRSlADHLRDLIprFLRRFSNGEPE 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 85 ----VSTFHAAALRILRVYGervgLRPGFVVYDEDDQTALLKEVLKElalsARPGPIKALLDraknrgvglkALLgelpe 160
Cdd:COG3972 237 dnvkLIVFHAWGGKLLKQYG----IPPLTFSQPNEAFDEACKALLEA----IQGEIIPPIYD----------AIL----- 293
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 161 yyaglsrgrlgdvlvryqealkaqgaldfgdillyalrlleedeevlrlvrkrarfihVDEYQDTSPVQYRF-TRLLAGE 239
Cdd:COG3972 294 ----------------------------------------------------------IDEAQDFEPEFLRLlYQLLKPP 315
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 240 EANLMAVGDPDQGIYSFRAADIKNILDFTRdypeaRVYRLEENYRSTEAILRFANAVI-----VKNALRLEKALRPVKRG 314
Cdd:COG3972 316 KKRLIWAYDEAQNIYGRKIPSAGGIPAGIG-----RDTILKKNYRNTRPILTFAHAFGmgllrPPGLLQGDAEDYEVERP 390
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 315 GEPVRLYRAE----------------DAREEARFVAEEIARL----GPPWDRYAVLYRTNAQSRLLEQALAgrgiparvv 374
Cdd:COG3972 391 GDKVTLIRPPepagrkgplpefkkydDRAEELEAIAEEIKKNlrdeGLRPSDIAVIYLGNNEAKELGDRLA--------- 461
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 375 ggvgfferaevkdllayarlalnpldavslkrvlntpprgigpatwarvqllaqekglppwEALKEaartfpraeplrhf 454
Cdd:COG3972 462 -------------------------------------------------------------AALER-------------- 466
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 455 valveelQDLVFgpaeaffrHLLEATDYPTYlreaYPEDaedrlenveellraakeaedlqdfldrvaltakaeepaeae 534
Cdd:COG3972 467 -------QGIDS--------YIAGARSDPNF----FWKD----------------------------------------- 486
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 504323521 535 GKVALMTLHNAKGLEFPVVFLVGVEEgllphrnsLSTLEGLEEERRLFYVGITRAQERLYLSHAEE 600
Cdd:COG3972 487 GGVTISTIHRAKGLEAPVVIIVGLDQ--------LAKGESLERLRNLLYVAMTRARGWLVVSGSGE 544
|
|
| AAA_19 |
pfam13245 |
AAA domain; |
13-90 |
6.30e-15 |
|
AAA domain;
Pssm-ID: 433059 [Multi-domain] Cd Length: 136 Bit Score: 71.87 E-value: 6.30e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 13 QRQAV--LHFEGPALVVAGAGSGKTRTVVHRVAYLVARRGVfPSEILAVTFTNKAAEEMRERLrgLVPGagevwvSTFHA 90
Cdd:pfam13245 1 QREAVrtALPSKVVLLTGGPGTGKTTTIRHIVALLVALGGV-SFPILLAAPTGRAAKRLSERT--GLPA------STIHR 71
|
|
| DExxQc_SF1-N |
cd17914 |
DEXQ-box helicase domain of superfamily 1 helicase; The superfamily (SF)1 family members ... |
23-113 |
2.23e-13 |
|
DEXQ-box helicase domain of superfamily 1 helicase; The superfamily (SF)1 family members include UvrD/Rep, Pif1-like, and Upf-1-like proteins. Like SF2, they do not form toroidal, predominantly hexameric structures like SF3-6. Their helicase core is surrounded by C and N-terminal domains with specific functions such as nucleases, RNA or DNA binding domains or domains engaged in protein-protein interactions. SF1 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438706 [Multi-domain] Cd Length: 121 Bit Score: 67.13 E-value: 2.23e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 23 PALVVAGAGSGKTRTVVHRVAYLVARRGVFPSEILAVTFTNKAAEEMRERLRGLVPGAGEVWVSTFHAAALRILRV--YG 100
Cdd:cd17914 1 LSLIQGPPGTGKTRVLVKIVAALMQNKNGEPGRILLVTPTNKAAAQLDNILVDEAAQILEPETSRLIDLALDQGRVilVG 80
|
90
....*....|...
gi 504323521 101 ERVGLRPGFVVYD 113
Cdd:cd17914 81 DHDQLGPVWRGAV 93
|
|
| recB |
PRK10876 |
exonuclease V subunit beta; Provisional |
167-294 |
3.98e-13 |
|
exonuclease V subunit beta; Provisional
Pssm-ID: 236784 [Multi-domain] Cd Length: 1181 Bit Score: 73.08 E-value: 3.98e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 167 RGRLG--DVLVRYQEALKAQGaldfGDILLYAlrlleedeevlrlVRKRARFIHVDEYQDTSPVQYR-FTRLLAGEEAN- 242
Cdd:PRK10876 346 RGELGfdDLLSRLDSALQSEG----GEALAAA-------------IRTRYPVAMIDEFQDTDPQQYRiFRRIYRHQPETa 408
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 504323521 243 LMAVGDPDQGIYSFRAADIknildFTrdYPEARV-----YRLEENYRSTEAILRFAN 294
Cdd:PRK10876 409 LLLIGDPKQAIYAFRGADI-----FT--YMKARSevsahYTLDTNWRSAPGMVNSVN 458
|
|
| UvrD_C_2 |
pfam13538 |
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety ... |
537-595 |
1.25e-10 |
|
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety of helicase enzymes. This domain has a AAA-like structural fold.
Pssm-ID: 463913 [Multi-domain] Cd Length: 52 Bit Score: 57.20 E-value: 1.25e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 504323521 537 VALMTLHNAKGLEFPVVFLVGVEegllphrnsLSTLEGLEEERRLFYVGITRAQERLYL 595
Cdd:pfam13538 2 AYALTVHKAQGSEFPAVFLVDPD---------LTAHYHSMLRRRLLYTAVTRARKKLVL 51
|
|
| SF1_C |
cd18786 |
C-terminal helicase domain of superfamily 1 DEAD/H-box helicases; Superfamily (SF)1 family ... |
536-595 |
3.18e-08 |
|
C-terminal helicase domain of superfamily 1 DEAD/H-box helicases; Superfamily (SF)1 family members include UvrD/Rep, Pif1-like, and Upf-1-like proteins. Similar to SF2 helicases, they do not form toroidal, predominantly hexameric structures like SF3-6. SF1 helicases are a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Their helicase core is surrounded by C- and N-terminal domains with specific functions such as nucleases, RNA or DNA binding domains, or domains engaged in protein-protein interactions. The core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350173 [Multi-domain] Cd Length: 89 Bit Score: 51.28 E-value: 3.18e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 536 KVALMTLHNAKGLEFPVVFLVGVEEGLLphrnslstlegleeERRLFYVGITRAQERLYL 595
Cdd:cd18786 42 LVGAITIDSSQGLTFDVVTLYLPTANSL--------------TPRRLYVALTRARKRLVI 87
|
|
| SF1_C_RecD |
cd18809 |
C-terminal helicase domain of RecD family helicases; RecD is a member of the RecBCD (EC 3.1.11. ... |
540-595 |
2.02e-05 |
|
C-terminal helicase domain of RecD family helicases; RecD is a member of the RecBCD (EC 3.1.11.5, Exonuclease V) complex. It is the alpha chain of the complex and functions as a 3'-5' helicase. The RecBCD enzyme is both a helicase that unwinds, or separates the strands of DNA, and a nuclease that makes single-stranded nicks in DNA. RecD family helicases are DEAD-like helicases belonging to superfamily (SF)1, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF2 helicases, SF1 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350196 [Multi-domain] Cd Length: 80 Bit Score: 43.32 E-value: 2.02e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 504323521 540 MTLHNAKGLEFPVVFLVgveeglLPHRNSLstlegleEERRLFYVGITRAQERLYL 595
Cdd:cd18809 36 MTIHKSQGSEFDRVIVV------LPTSHPM-------LSRGLLYTALTRARKLLTL 78
|
|
| DEAD-like_helicase_N |
cd17912 |
N-terminal helicase domain of the DEAD-box helicase superfamily; The DEAD-like helicase ... |
25-69 |
6.19e-05 |
|
N-terminal helicase domain of the DEAD-box helicase superfamily; The DEAD-like helicase superfamily is a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. The N-terminal domain contains the ATP-binding region.
Pssm-ID: 350670 [Multi-domain] Cd Length: 81 Bit Score: 41.74 E-value: 6.19e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 504323521 25 LVVAGAGSGKTRTVVHRVAYlvarRGVFPSEILAVTFTNKAAEEM 69
Cdd:cd17912 3 LHLGPTGSGKTLVAIQKIAS----AMSSGKSVLVVTPTKLLAHEI 43
|
|
| RecD |
COG0507 |
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) ... |
8-71 |
5.92e-04 |
|
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];
Pssm-ID: 440273 [Multi-domain] Cd Length: 514 Bit Score: 43.04 E-value: 5.92e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 504323521 8 PLNEAQRQAVLHFEGP---ALVVAGAGSGKTrTVVHRVAYLVARRGVfpsEILAVTFTNKAAEEMRE 71
Cdd:COG0507 124 TLSDEQREAVALALTTrrvSVLTGGAGTGKT-TTLRALLAALEALGL---RVALAAPTGKAAKRLSE 186
|
|
| RecD |
COG0507 |
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) ... |
540-595 |
6.85e-04 |
|
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];
Pssm-ID: 440273 [Multi-domain] Cd Length: 514 Bit Score: 42.66 E-value: 6.85e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 504323521 540 MTLHNAKGLEFPVVFLVGVEEgllpHRNSLStlegleeeRRLFYVGITRAQERLYL 595
Cdd:COG0507 445 ITVHKSQGSTFDRVILVLPSE----HSPLLS--------RELLYTALTRARELLTL 488
|
|
| AAA_12 |
pfam13087 |
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ... |
275-374 |
4.93e-03 |
|
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins.
Pssm-ID: 463780 [Multi-domain] Cd Length: 196 Bit Score: 38.68 E-value: 4.93e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 275 RVYRLEENYRSTEAILRFANAVIVKNAL--------RLEKALRPVKRGGEPVRLYRAEDARE-------------EARFV 333
Cdd:pfam13087 16 AVVMLDTQYRMHPEIMEFPSKLFYGGKLkdgpsvaeRPLPDDFHLPDPLGPLVFIDVDGSEEeesdggtsysneaEAELV 95
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 504323521 334 AEEIARL----GPPWDRYAVL--YRtnAQSRLLEQALAGRGIPARVV 374
Cdd:pfam13087 96 VQLVEKLiksgPEEPSDIGVItpYR--AQVRLIRKLLKRKLGGKLEI 140
|
|
| AAA_11 |
pfam13086 |
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ... |
13-101 |
5.95e-03 |
|
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins.
Pssm-ID: 404072 [Multi-domain] Cd Length: 248 Bit Score: 38.86 E-value: 5.95e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 13 QRQAVLHF---EGPALVVAGAGSGKTRTVVHRVAYLVAR---RGVFPSEILAVTFTNKAAEEMRERLRGLVPGAGevwvs 86
Cdd:pfam13086 2 QREAIRSAlssSHFTLIQGPPGTGKTTTIVELIRQLLSYpatSAAAGPRILVCAPSNAAVDNILERLLRKGQKYG----- 76
|
90
....*....|....*
gi 504323521 87 tfhaaaLRILRVYGE 101
Cdd:pfam13086 77 ------PKIVRIGHP 85
|
|
| recB |
PRK10876 |
exonuclease V subunit beta; Provisional |
22-74 |
6.76e-03 |
|
exonuclease V subunit beta; Provisional
Pssm-ID: 236784 [Multi-domain] Cd Length: 1181 Bit Score: 39.95 E-value: 6.76e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 504323521 22 GPALVVAGAGSGKTRTVVhrVAYLVARRGV-----FP-----SEILAVTFTNKAAEEMRERLR 74
Cdd:PRK10876 18 GERLIEASAGTGKTFTIA--ALYLRLLLGLggsaaFPrpltvEEILVVTFTEAATEELRGRIR 78
|
|
| DEXXQc_Helz-like |
cd18038 |
DEXXQ/H-box helicase domain of Helz-like helicase; This subfamily contains HELZ, Mov10L1, and ... |
9-79 |
6.97e-03 |
|
DEXXQ/H-box helicase domain of Helz-like helicase; This subfamily contains HELZ, Mov10L1, and similar proteins. Helicase with zinc finger (HELZ) acts as a helicase that plays a role in RNA metabolism during development. Moloney leukemia virus 10-like protein 1 (Mov10L1) binds Piwi-interacting RNA (piRNA) precursors to initiate piRNA processing. All are members of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350796 [Multi-domain] Cd Length: 229 Bit Score: 38.75 E-value: 6.97e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 504323521 9 LNEAQRQAVLHF----EGPA-LVVAG-AGSGKTRTVVHRVAYLVARrgvFPSE-ILAVTFTNKAAEEMRERLRGLVPG 79
Cdd:cd18038 2 LNDEQKLAVRNIvtgtSRPPpYIIFGpPGTGKTVTLVEAILQVLRQ---PPEArILVCAPSNSAADLLAERLLNALVT 76
|
|
| AAA_30 |
pfam13604 |
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ... |
8-73 |
7.65e-03 |
|
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. There is a Walker A and Walker B.
Pssm-ID: 433343 [Multi-domain] Cd Length: 191 Bit Score: 38.31 E-value: 7.65e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504323521 8 PLNEAQRQAVLHF----EGPALVVAGAGSGKTrTVVHRVAYLVARRGVfpsEILAVTFTNKAAEEMRERL 73
Cdd:pfam13604 1 TLNAEQAAAVRALltsgDRVAVLVGPAGTGKT-TALKALREAWEAAGY---RVIGLAPTGRAAKVLGEEL 66
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