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Conserved domains on  [gi|503596172|ref|WP_013830248|]
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MULTISPECIES: 50S ribosomal protein L24 [Mycobacteriaceae]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RplX COG0198
Ribosomal protein L24 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L24 ...
 1-105 7.26e-45

Ribosomal protein L24 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L24 is part of the Pathway/BioSystem: Ribosome 50S subunit


:

Pssm-ID: 439968 [Multi-domain]  Cd Length: 104  Bit Score: 140.58  E-value: 7.26e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503596172   1 MKVHKGDTVLVIAGKDKGAKGKVLQAYPARNRVLVQGVNRIKKHV-ANSANQagasSGGIVTQEAPIHVSNVMVVDS-DG 78
Cdd:COG0198    3 MKIKKGDTVIVIAGKDKGKRGKVLKVLPKKNRVIVEGVNIVKKHQkPNQQNP----QGGIIEKEAPIHISNVMLVDPkTG 78

                         90       100
                 ....*....|....*....|....*..
gi 503596172  79 KPTRVGYRVDEEsGKKVRVSKRNGKDI 105
Cdd:COG0198   79 KPTRVGFKVLED-GKKVRVCKKSGEVI 104
 
Name Accession Description Interval E-value
RplX COG0198
Ribosomal protein L24 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L24 ...
 1-105 7.26e-45

Ribosomal protein L24 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L24 is part of the Pathway/BioSystem: Ribosome 50S subunit


Pssm-ID: 439968 [Multi-domain]  Cd Length: 104  Bit Score: 140.58  E-value: 7.26e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503596172   1 MKVHKGDTVLVIAGKDKGAKGKVLQAYPARNRVLVQGVNRIKKHV-ANSANQagasSGGIVTQEAPIHVSNVMVVDS-DG 78
Cdd:COG0198    3 MKIKKGDTVIVIAGKDKGKRGKVLKVLPKKNRVIVEGVNIVKKHQkPNQQNP----QGGIIEKEAPIHISNVMLVDPkTG 78

                         90       100
                 ....*....|....*....|....*..
gi 503596172  79 KPTRVGYRVDEEsGKKVRVSKRNGKDI 105
Cdd:COG0198   79 KPTRVGFKVLED-GKKVRVCKKSGEVI 104
rplX_bact TIGR01079
ribosomal protein L24, bacterial/organelle; This model recognizes bacterial and organellar ...
 1-105 3.46e-35

ribosomal protein L24, bacterial/organelle; This model recognizes bacterial and organellar forms of ribosomal protein L24. It excludes eukaryotic and archaeal forms, designated L26 in eukaryotes. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 273431 [Multi-domain]  Cd Length: 102  Bit Score: 115.83  E-value: 3.46e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503596172    1 MKVHKGDTVLVIAGKDKGAKGKVLQAYPARNRVLVQGVNRIKKHVANSANQAgasSGGIVTQEAPIHVSNVMVVD-SDGK 79
Cdd:TIGR01079   1 MKIKKGDTVKVISGKDKGKRGKVLKVLPKKNKVIVEGVNMVKKHVKPVPANR---QGGIIEKEAPIHISNVMLFDpKTGK 77

                          90       100
                  ....*....|....*....|....*.
gi 503596172   80 PTRVGYRVDEEsGKKVRVSKRNGKDI 105
Cdd:TIGR01079  78 ATRVGYRFEED-GKKVRVFKKNGEII 102
KOW_RPL26 cd06089
KOW motif of Ribosomal Protein L26; RPL26 and its bacterial paralogs RPL24 have a KOW motif at ...
 6-73 2.32e-21

KOW motif of Ribosomal Protein L26; RPL26 and its bacterial paralogs RPL24 have a KOW motif at their N terminal. KOW domain is known as an RNA-binding motif that is shared so far among some families of ribosomal proteins, the essential bacterial transcriptional elongation factor NusG, the eukaryotic chromatin elongation factor Spt5, the higher eukaryotic KIN17 proteins and Mtr4. RPL26 makes a very minor contributions to the biogenesis, structure, and function of 60s ribosomal subunits. However, RPL24 is essential to generate the first intermediate during 50s ribosomal subunits assembly. RPL26 have an extra-ribosomal function to enhances p53 translation after DNA damage.


Pssm-ID: 240513  Cd Length: 65  Bit Score: 79.87  E-value: 2.32e-21
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 503596172   6 GDTVLVIAGKDKGAKGKVLQAYPARNRVLVQGVNRIKKHVANSANQagaSSGGIVTQEAPIHVSNVMV 73
Cdd:cd06089    1 GDEVQVIRGKDKGKQGKVLKVDRKKNRVIVEGVNVVKKHVKPSQEN---PQGGIIEVEAPIHISNVML 65
ribosomal_L24 pfam17136
Ribosomal proteins 50S L24/mitochondrial 39S L24; This is the family of bacterial 50S ...
 38-102 8.31e-21

Ribosomal proteins 50S L24/mitochondrial 39S L24; This is the family of bacterial 50S ribosomal subunit proteins L24. It also carries some mitochondrial 39S L24 proteins.


Pssm-ID: 465359  Cd Length: 60  Bit Score: 78.26  E-value: 8.31e-21
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 503596172   38 VNRIKKHVANSANQagaSSGGIVTQEAPIHVSNVMVVD-SDGKPTRVGYRvdeESGKKVRVSKRNG 102
Cdd:pfam17136   1 VNMVKKHVKPSQQN---PQGGIIEKEAPIHVSNVMLVDpKCGKPTRVGFK---EDGKKVRVSKKTG 60
rplX PRK12281
50S ribosomal protein L24; Reviewed
 1-74 3.14e-18

50S ribosomal protein L24; Reviewed


Pssm-ID: 183399  Cd Length: 76  Bit Score: 71.99  E-value: 3.14e-18
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 503596172   1 MKVHKGDTVLVIAGKDKGAKGKVLQAYPARNRVLVQGVNRIKKHVANSANQAgasSGGIVTQEAPIHVSNVMVV 74
Cdd:PRK12281   5 LKVKKGDMVKVIAGDDKGKTGKVLAVLPKKNRVIVEGVKIAKKAIKPSQKNP---NGGFIEKEMPIHISNVKKV 75
 
Name Accession Description Interval E-value
RplX COG0198
Ribosomal protein L24 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L24 ...
 1-105 7.26e-45

Ribosomal protein L24 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L24 is part of the Pathway/BioSystem: Ribosome 50S subunit


Pssm-ID: 439968 [Multi-domain]  Cd Length: 104  Bit Score: 140.58  E-value: 7.26e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503596172   1 MKVHKGDTVLVIAGKDKGAKGKVLQAYPARNRVLVQGVNRIKKHV-ANSANQagasSGGIVTQEAPIHVSNVMVVDS-DG 78
Cdd:COG0198    3 MKIKKGDTVIVIAGKDKGKRGKVLKVLPKKNRVIVEGVNIVKKHQkPNQQNP----QGGIIEKEAPIHISNVMLVDPkTG 78

                         90       100
                 ....*....|....*....|....*..
gi 503596172  79 KPTRVGYRVDEEsGKKVRVSKRNGKDI 105
Cdd:COG0198   79 KPTRVGFKVLED-GKKVRVCKKSGEVI 104
rplX_bact TIGR01079
ribosomal protein L24, bacterial/organelle; This model recognizes bacterial and organellar ...
 1-105 3.46e-35

ribosomal protein L24, bacterial/organelle; This model recognizes bacterial and organellar forms of ribosomal protein L24. It excludes eukaryotic and archaeal forms, designated L26 in eukaryotes. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 273431 [Multi-domain]  Cd Length: 102  Bit Score: 115.83  E-value: 3.46e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503596172    1 MKVHKGDTVLVIAGKDKGAKGKVLQAYPARNRVLVQGVNRIKKHVANSANQAgasSGGIVTQEAPIHVSNVMVVD-SDGK 79
Cdd:TIGR01079   1 MKIKKGDTVKVISGKDKGKRGKVLKVLPKKNKVIVEGVNMVKKHVKPVPANR---QGGIIEKEAPIHISNVMLFDpKTGK 77

                          90       100
                  ....*....|....*....|....*.
gi 503596172   80 PTRVGYRVDEEsGKKVRVSKRNGKDI 105
Cdd:TIGR01079  78 ATRVGYRFEED-GKKVRVFKKNGEII 102
KOW_RPL26 cd06089
KOW motif of Ribosomal Protein L26; RPL26 and its bacterial paralogs RPL24 have a KOW motif at ...
 6-73 2.32e-21

KOW motif of Ribosomal Protein L26; RPL26 and its bacterial paralogs RPL24 have a KOW motif at their N terminal. KOW domain is known as an RNA-binding motif that is shared so far among some families of ribosomal proteins, the essential bacterial transcriptional elongation factor NusG, the eukaryotic chromatin elongation factor Spt5, the higher eukaryotic KIN17 proteins and Mtr4. RPL26 makes a very minor contributions to the biogenesis, structure, and function of 60s ribosomal subunits. However, RPL24 is essential to generate the first intermediate during 50s ribosomal subunits assembly. RPL26 have an extra-ribosomal function to enhances p53 translation after DNA damage.


Pssm-ID: 240513  Cd Length: 65  Bit Score: 79.87  E-value: 2.32e-21
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 503596172   6 GDTVLVIAGKDKGAKGKVLQAYPARNRVLVQGVNRIKKHVANSANQagaSSGGIVTQEAPIHVSNVMV 73
Cdd:cd06089    1 GDEVQVIRGKDKGKQGKVLKVDRKKNRVIVEGVNVVKKHVKPSQEN---PQGGIIEVEAPIHISNVML 65
ribosomal_L24 pfam17136
Ribosomal proteins 50S L24/mitochondrial 39S L24; This is the family of bacterial 50S ...
 38-102 8.31e-21

Ribosomal proteins 50S L24/mitochondrial 39S L24; This is the family of bacterial 50S ribosomal subunit proteins L24. It also carries some mitochondrial 39S L24 proteins.


Pssm-ID: 465359  Cd Length: 60  Bit Score: 78.26  E-value: 8.31e-21
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 503596172   38 VNRIKKHVANSANQagaSSGGIVTQEAPIHVSNVMVVD-SDGKPTRVGYRvdeESGKKVRVSKRNG 102
Cdd:pfam17136   1 VNMVKKHVKPSQQN---PQGGIIEKEAPIHVSNVMLVDpKCGKPTRVGFK---EDGKKVRVSKKTG 60
rplX PRK12281
50S ribosomal protein L24; Reviewed
 1-74 3.14e-18

50S ribosomal protein L24; Reviewed


Pssm-ID: 183399  Cd Length: 76  Bit Score: 71.99  E-value: 3.14e-18
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 503596172   1 MKVHKGDTVLVIAGKDKGAKGKVLQAYPARNRVLVQGVNRIKKHVANSANQAgasSGGIVTQEAPIHVSNVMVV 74
Cdd:PRK12281   5 LKVKKGDMVKVIAGDDKGKTGKVLAVLPKKNRVIVEGVKIAKKAIKPSQKNP---NGGFIEKEMPIHISNVKKV 75
rpl24 CHL00141
ribosomal protein L24; Validated
 1-80 1.06e-15

ribosomal protein L24; Validated


Pssm-ID: 214374  Cd Length: 83  Bit Score: 65.82  E-value: 1.06e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503596172   1 MKVHKGDTVLVIAGKDKGAKGKVLQAYPARNRVLVQGVNRIKKHVansANQAGASSGGIVTQEAPIHVSNVMVVDSDGKP 80
Cdd:CHL00141   7 MHVKIGDTVKIISGSDKGKIGEVLKIIKKSNKVIVKGINIKFKHI---KPNKENEVGEIKQFEAPIHSSNVMLYNEESNI 83
Ribosomal_L26 pfam16906
Ribosomal proteins L26 eukaryotic, L24P archaeal; Ribosomal_L26 is a family of the 50S and the ...
 1-74 1.11e-07

Ribosomal proteins L26 eukaryotic, L24P archaeal; Ribosomal_L26 is a family of the 50S and the 60S ribosomal proteins from eukaryotes - L26 - and archaea - L25.


Pssm-ID: 465307 [Multi-domain]  Cd Length: 114  Bit Score: 45.96  E-value: 1.11e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 503596172    1 MKVHKGDTVLVIAGKDKGAKGKVLQAYPARNRVLVQGVNRIKkhvANSAnqagassggivTQEAPIHVSNVMVV 74
Cdd:pfam16906  40 LPIRKGDEVKVVRGDFKGREGKVVQVYRKKYRIHVEGVTREK---ANGT-----------TVPVPIHPSKVVIT 99
rplX_A_E TIGR01080
ribosomal protein uL24, archaeal/eukaryotic form; This model represents the archaeal and ...
 1-75 3.11e-06

ribosomal protein uL24, archaeal/eukaryotic form; This model represents the archaeal and eukaryotic branch of the ribosomal protein L24p/L26e family. Bacterial and organellar forms are represented by related model TIGR01079. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 273432  Cd Length: 114  Bit Score: 42.53  E-value: 3.11e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 503596172    1 MKVHKGDTVLVIAGKDKGAKGKVLQAYPARNRVLVQGVNRIKkhvansanQAGAssggivTQEAPIHVSNVMVVD 75
Cdd:TIGR01080  40 LPIRKGDEVRIVRGDFKGHEGKVSKVDRKRYRIYVEGVTKEK--------VDGT------EVPVPLHPSNVMITK 100
KOW pfam00467
KOW motif; This family has been extended to coincide with ref. The KOW (Kyprides, Ouzounis, ...
 5-35 2.03e-04

KOW motif; This family has been extended to coincide with ref. The KOW (Kyprides, Ouzounis, Woese) motif is found in a variety of ribosomal proteins and NusG.


Pssm-ID: 425698 [Multi-domain]  Cd Length: 32  Bit Score: 35.83  E-value: 2.03e-04
                          10        20        30
                  ....*....|....*....|....*....|.
gi 503596172    5 KGDTVLVIAGKDKGAKGKVLQAYPARNRVLV 35
Cdd:pfam00467   1 KGDVVRVIAGPFKGKVGKVVEVDDKKNRVLV 31
PTZ00194 PTZ00194
60S ribosomal protein L26; Provisional
 1-42 2.31e-03

60S ribosomal protein L26; Provisional


Pssm-ID: 185508  Cd Length: 143  Bit Score: 35.11  E-value: 2.31e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 503596172   1 MKVHKGDTVLVIAGKDKGAKGKVLQAYPARNRVLVQGVNRIK 42
Cdd:PTZ00194  45 MPVRKDDEVMVVRGHHKGREGKVTAVYRKKWVIHIEKITREK 86
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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