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Conserved domains on  [gi|503024272|ref|WP_013259248|]
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enoyl-CoA hydratase/isomerase family protein [Desulfarculus baarsii]

Protein Classification

enoyl-CoA hydratase/isomerase family protein( domain architecture ID 10787157)

enoyl-CoA hydratase/isomerase family protein similar to human ethylmalonyl-CoA decarboxylase that decarboxylates ethylmalonyl-CoA, a potentially toxic metabolite, to form butyryl-CoA

CATH:  3.90.226.10
Gene Ontology:  GO:0016829
PubMed:  12467702|22016388

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
 9-253 1.20e-86

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


:

Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 257.79  E-value: 1.20e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   9 IEEQIAVVTIDHP-PMNALDEATKEAIGRVFDELDqRRDELRAAILRGAGdKAFVAGADINSFLTL-TPDAAKRRQKRTH 86
Cdd:COG1024    5 REGGVATITLNRPeKLNALSLEMLAELAAALDEAE-ADPDVRVVVLTGAG-KAFCAGADLKELAAAaDPEEARAFARGLQ 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  87 AIVAKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTVRSLRHAPLGKVKELIFGGEM 166
Cdd:COG1024   83 RLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKELLLTGRR 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 167 ISAQEALACGLIEKVVPRGQALEAAMTLARRIAGRGPLGVAAAKKSINRARELSVAMGLESESDLWSGLCATEDQKEGAR 246
Cdd:COG1024  163 IDAEEALELGLVNRVVPDDELLAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAREGIA 242


                 ....*..
gi 503024272 247 AFLEKRP 253
Cdd:COG1024  243 AFLEKRK 249
 
Name Accession Description Interval E-value
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
 9-253 1.20e-86

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 257.79  E-value: 1.20e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   9 IEEQIAVVTIDHP-PMNALDEATKEAIGRVFDELDqRRDELRAAILRGAGdKAFVAGADINSFLTL-TPDAAKRRQKRTH 86
Cdd:COG1024    5 REGGVATITLNRPeKLNALSLEMLAELAAALDEAE-ADPDVRVVVLTGAG-KAFCAGADLKELAAAaDPEEARAFARGLQ 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  87 AIVAKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTVRSLRHAPLGKVKELIFGGEM 166
Cdd:COG1024   83 RLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKELLLTGRR 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 167 ISAQEALACGLIEKVVPRGQALEAAMTLARRIAGRGPLGVAAAKKSINRARELSVAMGLESESDLWSGLCATEDQKEGAR 246
Cdd:COG1024  163 IDAEEALELGLVNRVVPDDELLAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAREGIA 242


                 ....*..
gi 503024272 247 AFLEKRP 253
Cdd:COG1024  243 AFLEKRK 249
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
 2-259 5.59e-76

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 231.06  E-value: 5.59e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   2 AELCSYVIEEQIAVVTIDHPPMNALDEATKEAIGRVFDELDQRrDELRAAILRGAGdKAFVAGADINSFLTLT-PDAAKR 80
Cdd:PRK07658   1 MKFLSVRVEDHVAVITLNHPPANALSSQVLHELSELLDQVEKD-DNVRVVVIHGEG-RFFSAGADIKEFTSVTeAEQATE 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  81 RQKRTHAIVAKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTVRSLRHAPLGKVKEL 160
Cdd:PRK07658  79 LAQLGQVTFERVEKFSKPVIAAIHGAALGGGLELAMSCHIRFATESAKLGLPELNLGLIPGFAGTQRLPRYVGKAKALEM 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 161 IFGGEMISAQEALACGLIEKVVPRGQALEAAMTLARRIAGRGPLGVAAAKKSINRARELSVAMGLESESDLWSGLCATED 240
Cdd:PRK07658 159 MLTSEPITGAEALKWGLVNGVFPEETLLDDAKKLAKKIAGKSPATTRAVLELLQTTKSSSYYEGVKREAKIFGEVFTSED 238

                        250
                 ....*....|....*....
gi 503024272 241 QKEGARAFLEKRPPKFLGR 259
Cdd:PRK07658 239 AKEGVQAFLEKRKPSFSGK 257
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
 5-198 1.44e-60

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 189.69  E-value: 1.44e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   5 CSYVIEEQIAVVTIDHPP-MNALDEATKEAIGRVFDELDqRRDELRAAILRGAGdKAFVAGADINSFLTLTPDAAKRRQ- 82
Cdd:cd06558    1 VLVERDGGVATITLNRPEkRNALSLEMLDELAAALDEAE-ADPDVRVVVLTGAG-KAFCAGADLKELAALSDAGEEARAf 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  83 -KRTHAIVAKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTVRSLRHAPLGKVKELI 161
Cdd:cd06558   79 iRELQELLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPARARELL 158

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 503024272 162 FGGEMISAQEALACGLIEKVVPRGQALEAAMTLARRI 198
Cdd:cd06558  159 LTGRRISAEEALELGLVDEVVPDEELLAAALELARRL 195
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 9-259 1.98e-52

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 170.62  E-value: 1.98e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272    9 IEEQIAVVTIDHP-PMNALDEATKEAIGRVFDELDQRRdELRAAILRGaGDKAFVAGADINSFLTLTPDAAKRRQKRTHA 87
Cdd:pfam00378   2 INAGVAVITLNRPeAVNALSAELITELIQALEKLRTDP-SVRAVVLTG-GDKAFCAGADLKEMYGEGPAHQALYRENVLD 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   88 IVAKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTVRSLRHAPLGKVKELIFGGEMI 167
Cdd:pfam00378  80 LWTLLYTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHSKAMEMLLLGRRI 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  168 SAQEALACGLIEKVVPRGQALEAAMTLARRIAGRGPLGVAAAKKSINRARELSVAMGLESESDLWSGLCATEDQKEGARA 247
Cdd:pfam00378 160 SAQEALKWGLVDKVVPEDQLLDEARELAEKLAEKSPAALAQLKKALNAKLEDALPTQLEAEARLFYSTFSKDDIIEGLQA 239

                         250
                  ....*....|..
gi 503024272  248 FLEKRPPKFLGR 259
Cdd:pfam00378 240 FLEKRKPPWEDQ 251
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
 6-219 5.30e-27

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 109.54  E-value: 5.30e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272    6 SYVIEEQIAVVTIDHP--PMNALDEATKEAIGRVFDELdQRRDELRAAILRGAGDKAFVAGADINSFLTL-TPDAAKRRQ 82
Cdd:TIGR02441  16 HYEVKGDVAVVKIDSPnsKVNTLSKELFAEFKEVMNEL-WTNEAIKSAVLISGKPGSFVAGADIQMIAACkTAQEVTQLS 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   83 KRTHAIVAKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYA--EEQSRFGFPEVNLAIFPGNGGTVRSLRHAPLGKVKEL 160
Cdd:TIGR02441  95 QEGQEMFERIEKSQKPIVAAISGSCLGGGLELALACHYRIAtkDRKTLLGLPEVMLGLLPGAGGTQRLPKLTGVPAALDM 174

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 503024272  161 IFGGEMISAQEALACGLIEKVV-PRGQALEAA----MTLARRIAGRGPLGVAAAKKSINRAREL 219
Cdd:TIGR02441 175 MLTGKKIRADRAKKMGIVDQLVdPLGPGLKPAeentIEYLEEVAVKFAQGLANGKLSINRDKGL 238
 
Name Accession Description Interval E-value
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
 9-253 1.20e-86

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 257.79  E-value: 1.20e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   9 IEEQIAVVTIDHP-PMNALDEATKEAIGRVFDELDqRRDELRAAILRGAGdKAFVAGADINSFLTL-TPDAAKRRQKRTH 86
Cdd:COG1024    5 REGGVATITLNRPeKLNALSLEMLAELAAALDEAE-ADPDVRVVVLTGAG-KAFCAGADLKELAAAaDPEEARAFARGLQ 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  87 AIVAKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTVRSLRHAPLGKVKELIFGGEM 166
Cdd:COG1024   83 RLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKELLLTGRR 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 167 ISAQEALACGLIEKVVPRGQALEAAMTLARRIAGRGPLGVAAAKKSINRARELSVAMGLESESDLWSGLCATEDQKEGAR 246
Cdd:COG1024  163 IDAEEALELGLVNRVVPDDELLAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAREGIA 242


                 ....*..
gi 503024272 247 AFLEKRP 253
Cdd:COG1024  243 AFLEKRK 249
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
 2-259 5.59e-76

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 231.06  E-value: 5.59e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   2 AELCSYVIEEQIAVVTIDHPPMNALDEATKEAIGRVFDELDQRrDELRAAILRGAGdKAFVAGADINSFLTLT-PDAAKR 80
Cdd:PRK07658   1 MKFLSVRVEDHVAVITLNHPPANALSSQVLHELSELLDQVEKD-DNVRVVVIHGEG-RFFSAGADIKEFTSVTeAEQATE 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  81 RQKRTHAIVAKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTVRSLRHAPLGKVKEL 160
Cdd:PRK07658  79 LAQLGQVTFERVEKFSKPVIAAIHGAALGGGLELAMSCHIRFATESAKLGLPELNLGLIPGFAGTQRLPRYVGKAKALEM 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 161 IFGGEMISAQEALACGLIEKVVPRGQALEAAMTLARRIAGRGPLGVAAAKKSINRARELSVAMGLESESDLWSGLCATED 240
Cdd:PRK07658 159 MLTSEPITGAEALKWGLVNGVFPEETLLDDAKKLAKKIAGKSPATTRAVLELLQTTKSSSYYEGVKREAKIFGEVFTSED 238

                        250
                 ....*....|....*....
gi 503024272 241 QKEGARAFLEKRPPKFLGR 259
Cdd:PRK07658 239 AKEGVQAFLEKRKPSFSGK 257
PRK05809 PRK05809
short-chain-enoyl-CoA hydratase;
9-259 8.30e-70

short-chain-enoyl-CoA hydratase;


Pssm-ID: 180270 [Multi-domain]  Cd Length: 260  Bit Score: 215.38  E-value: 8.30e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   9 IEEQIAVVTIDHP-PMNALDEATKEAIGRVFDELdQRRDELRAAILRGAGDKAFVAGADINSFLTLTPDAAKRRQKRTHA 87
Cdd:PRK05809  10 KEGHIAVVTINRPkALNALNSETLKELDTVLDDI-ENDDNVYAVILTGAGEKAFVAGADISEMKDLNEEEGRKFGLLGNK 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  88 IVAKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTVRSLRHAPLGKVKELIFGGEMI 167
Cdd:PRK05809  89 VFRKLENLDKPVIAAINGFALGGGCELSMACDIRIASEKAKFGQPEVGLGITPGFGGTQRLARIVGPGKAKELIYTGDMI 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 168 SAQEALACGLIEKVVPRGQALEAAMTLARRIAGRGPLGVAAAKKSINRARELSVAMGLESESDLWSGLCATEDQKEGARA 247
Cdd:PRK05809 169 NAEEALRIGLVNKVVEPEKLMEEAKALANKIAANAPIAVKLCKDAINRGMQVDIDTAVAIEAEDFGECFSTEDQTEGMTA 248

                        250
                 ....*....|..
gi 503024272 248 FLEKRPPKFLGR 259
Cdd:PRK05809 249 FVEKREKNFKNK 260
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
 1-258 2.54e-68

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 211.90  E-value: 2.54e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   1 MAELCSY-VIEEQIAVVTIDHP-PMNALDEATKEAIGRVFDELDQRRDeLRAAILRGAGDKAFVAGADINSFLTLTPDAA 78
Cdd:PRK07657   1 MLQNISVdYVTPHVVKITLNRPrAANALSLALLEELQNILTQINEEAN-VRVVILTGAGEKAFCAGADLKERAGMNEEQV 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  79 KRRQKRTHAIVAKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTVRSLRHAPLGKVK 158
Cdd:PRK07657  80 RHAVSLIRTTMEMVEQLPQPVIAAINGIALGGGLELALACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAK 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 159 ELIFGGEMISAQEALACGLIEKVVPRGQALEAAMTLARRIAGRGPLGVAAAKKSINRARELSVAMGLESESDLWSGLCAT 238
Cdd:PRK07657 160 ELIYTGRRISAQEAKEIGLVEFVVPAHLLEEKAIEIAEKIASNGPIAVRQAKEAISNGIQVDLHTGLQIEKQAYEGTIPT 239

                        250       260
                 ....*....|....*....|
gi 503024272 239 EDQKEGARAFLEKRPPKFLG 258
Cdd:PRK07657 240 KDRLEGLQAFKEKRKPMYKG 259
PRK09076 PRK09076
enoyl-CoA hydratase; Provisional
 1-254 3.11e-61

enoyl-CoA hydratase; Provisional


Pssm-ID: 236373 [Multi-domain]  Cd Length: 258  Bit Score: 193.60  E-value: 3.11e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   1 MAELCSYVIEEQIAVVTIDHPPMNALDEATKEAIGRVFDELDQRRDeLRAAILRGAGDKAFVAGADINSFLTLTPDAAKR 80
Cdd:PRK09076   1 MMIELDLEIDGHVAILTLNNPPANTWTADSLQALKQLVLELNADKD-VYALVITGDGEKFFSAGADLNLFADGDKAVARE 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  81 RQKRTHAIVAKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTVRSLRHAPLGKVKEL 160
Cdd:PRK09076  80 MARRFGEAFEALSAFRGVSIAAINGYAMGGGLECALACDIRIAEEQAQMALPEASVGLLPCAGGTQNLPWLVGEGWAKRM 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 161 IFGGEMISAQEALACGLIEKVVPRGQALEAAMTLARRIAGRGPLGVAAAKKSINRARELSVAMGLESESDLWSGLCATED 240
Cdd:PRK09076 160 ILCGERVDAATALRIGLVEEVVEKGEAREAALALAQKVANQSPSAVAACKTLIQAARNGPRAAALALERELFVDLFDTED 239

                        250
                 ....*....|....
gi 503024272 241 QKEGARAFLEKRPP 254
Cdd:PRK09076 240 QREGVNAFLEKRAP 253
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
 5-198 1.44e-60

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 189.69  E-value: 1.44e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   5 CSYVIEEQIAVVTIDHPP-MNALDEATKEAIGRVFDELDqRRDELRAAILRGAGdKAFVAGADINSFLTLTPDAAKRRQ- 82
Cdd:cd06558    1 VLVERDGGVATITLNRPEkRNALSLEMLDELAAALDEAE-ADPDVRVVVLTGAG-KAFCAGADLKELAALSDAGEEARAf 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  83 -KRTHAIVAKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTVRSLRHAPLGKVKELI 161
Cdd:cd06558   79 iRELQELLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPARARELL 158

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 503024272 162 FGGEMISAQEALACGLIEKVVPRGQALEAAMTLARRI 198
Cdd:cd06558  159 LTGRRISAEEALELGLVDEVVPDEELLAAALELARRL 195
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
 10-259 6.48e-59

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 187.57  E-value: 6.48e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  10 EEQIAVVTIDHP-PMNALDEATKEAIGRVFDELDQRrDELRAAILRGaGDKAFVAGADINSFLTLTPdaAKRRQKRTHAI 88
Cdd:PRK08138  15 ADGVALLRLNRPeARNALNMEVRQQLAEHFTELSED-PDIRAIVLTG-GEKVFAAGADIKEFATAGA--IEMYLRHTERY 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  89 VAKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTVRSLRhaPLGKVK--ELIFGGEM 166
Cdd:PRK08138  91 WEAIAQCPKPVIAAVNGYALGGGCELAMHADIIVAGESASFGQPEIKVGLMPGAGGTQRLVR--AVGKFKamRMALTGCM 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 167 ISAQEALACGLIEKVVPRGQALEAAMTLARRIAGRGPLGVAAAKKSINRARELSVAMGLESESDLWSGLCATEDQKEGAR 246
Cdd:PRK08138 169 VPAPEALAIGLVSEVVEDEQTLPRALELAREIARMPPLALAQIKEVVLAGADAPLDAALALERKAFQLLFDSEDQKEGMD 248

                        250
                 ....*....|...
gi 503024272 247 AFLEKRPPKFLGR 259
Cdd:PRK08138 249 AFLEKRKPAYKGK 261
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
 8-259 1.55e-57

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 183.92  E-value: 1.55e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   8 VIEEQIAVVTIDHP-PMNALDEATKEAIGRVFDELdQRRDELRAAILRGAGdKAFVAGADINSFLTlTPDAAKRRQKRTH 86
Cdd:PRK06688  10 ELEDGVLTITINRPdKKNALTAAMYQALADALEAA-ATDPAVRVVVLTGAG-RAFSAGGDIKDFPK-APPKPPDELAPVN 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  87 AIVAKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTVRSLRHAPLGKVKELIFGGEM 166
Cdd:PRK06688  87 RFLRAIAALPKPVVAAVNGPAVGVGVSLALACDLVYASESAKFSLPFAKLGLCPDAGGSALLPRLIGRARAAEMLLLGEP 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 167 ISAQEALACGLIEKVVPRGQALEAAMTLARRIAGRGPLGVAAAKKSINRARELSVAMGLESESDLWSGLCATEDQKEGAR 246
Cdd:PRK06688 167 LSAEEALRIGLVNRVVPAAELDAEADAQAAKLAAGPASALRYTKRAINAATLTELEEALAREAAGFGRLLRTPDFREGAT 246

                        250
                 ....*....|...
gi 503024272 247 AFLEKRPPKFLGR 259
Cdd:PRK06688 247 AFIEKRKPDFTGF 259
PRK06144 PRK06144
enoyl-CoA hydratase; Provisional
 7-259 2.01e-57

enoyl-CoA hydratase; Provisional


Pssm-ID: 180424 [Multi-domain]  Cd Length: 262  Bit Score: 184.04  E-value: 2.01e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   7 YVIEEQIAVVTIDHP-PMNALDEATKEAIGRVFDELDqRRDELRAAILRGAGDKAFVAGADINSFLTL-TPDAAKRRQKR 84
Cdd:PRK06144  12 LEVRGGIARITFNRPaARNAMTWAMYEGLAEICEAIA-ADPSIRAVVLRGAGDKAFVAGTDIAQFRAFsTAEDAVAYERR 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  85 THAIVAKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPevnLAIFPGNGGTVRSLR----HAPLGKVKEL 160
Cdd:PRK06144  91 IDRVLGALEQLRVPTIAAIAGACVGGGAAIAAACDLRIATPSARFGFP---IARTLGNCLSMSNLArlvaLLGAARVKDM 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 161 IFGGEMISAQEALACGLIEKVVPRGQALEAAMTLARRIAGRGPLGVAAAKKSINRARELSVAMGleseSDLWSGLCATED 240
Cdd:PRK06144 168 LFTARLLEAEEALAAGLVNEVVEDAALDARADALAELLAAHAPLTLRATKEALRRLRREGLPDG----DDLIRMCYMSED 243

                        250
                 ....*....|....*....
gi 503024272 241 QKEGARAFLEKRPPKFLGR 259
Cdd:PRK06144 244 FREGVEAFLEKRPPKWKGR 262
PRK06495 PRK06495
enoyl-CoA hydratase/isomerase family protein;
1-259 3.04e-56

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 168580 [Multi-domain]  Cd Length: 257  Bit Score: 180.66  E-value: 3.04e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   1 MAELCSYVIEEQIAVVTIDHPPMNALDEATKEAIGRVFDELDQRrDELRAAILRGAGdKAFVAGADINSFLTLT--PDAA 78
Cdd:PRK06495   2 MMSQLKLEVSDHVAVVTLDNPPVNALSRELRDELIAVFDEISER-PDVRVVVLTGAG-KVFCAGADLKGRPDVIkgPGDL 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  79 KRRQKRTHAIVAKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFpgnGGTVRSLRHAPLGKVK 158
Cdd:PRK06495  80 RAHNRRTRECFHAIRECAKPVIAAVNGPALGAGLGLVASCDIIVASENAVFGLPEIDVGLA---GGGKHAMRLFGHSLTR 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 159 ELIFGGEMISAQEALACGLIEKVVPRGQALEAAMTLARRIAGRGPLGVAAAKKSINRARELSVAMGLESESDLWSGLCAT 238
Cdd:PRK06495 157 RMMLTGYRVPAAELYRRGVIEACLPPEELMPEAMEIAREIASKSPLATRLAKDALNTIENMSLRDGYRYEQDITAKLAKT 236

                        250       260
                 ....*....|....*....|.
gi 503024272 239 EDQKEGARAFLEKRPPKFLGR 259
Cdd:PRK06495 237 EDAKEAQRAFLEKRPPVFKGR 257
PRK09674 PRK09674
enoyl-CoA hydratase-isomerase; Provisional
 10-259 1.89e-55

enoyl-CoA hydratase-isomerase; Provisional


Pssm-ID: 182026 [Multi-domain]  Cd Length: 255  Bit Score: 178.81  E-value: 1.89e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  10 EEQIAVVTIDHP-PMNALDEATKEAIGRVFdELDQRRDELRAAILRGAGdKAFVAGADINSFLTltPDAAKRRQKRTHAI 88
Cdd:PRK09674   9 QQRVLLLTLNRPeARNALNNALLTQLVNEL-EAAATDTSIGVCVITGNA-RFFAAGADLNEMAE--KDLAATLNDPRPQL 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  89 VAKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTVRSLRHAPLGKVKELIFGGEMIS 168
Cdd:PRK09674  85 WQRLQAFNKPLIAAVNGYALGAGCELALLCDIVIAGENARFGLPEITLGIMPGAGGTQRLIRSVGKSLASQMVLTGESIT 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 169 AQEALACGLIEKVVPRGQALEAAMTLARRIAGRGPLGVAAAKKSINRARELSVAMGLESESDLWSGLCATEDQKEGARAF 248
Cdd:PRK09674 165 AQQAQQAGLVSEVFPPELTLERALQLASKIARHSPLALRAAKQALRQSQEVDLQAGLAQERQLFTLLAATEDRHEGISAF 244

                        250
                 ....*....|.
gi 503024272 249 LEKRPPKFLGR 259
Cdd:PRK09674 245 LEKRTPDFKGR 255
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 9-259 1.98e-52

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 170.62  E-value: 1.98e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272    9 IEEQIAVVTIDHP-PMNALDEATKEAIGRVFDELDQRRdELRAAILRGaGDKAFVAGADINSFLTLTPDAAKRRQKRTHA 87
Cdd:pfam00378   2 INAGVAVITLNRPeAVNALSAELITELIQALEKLRTDP-SVRAVVLTG-GDKAFCAGADLKEMYGEGPAHQALYRENVLD 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   88 IVAKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTVRSLRHAPLGKVKELIFGGEMI 167
Cdd:pfam00378  80 LWTLLYTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHSKAMEMLLLGRRI 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  168 SAQEALACGLIEKVVPRGQALEAAMTLARRIAGRGPLGVAAAKKSINRARELSVAMGLESESDLWSGLCATEDQKEGARA 247
Cdd:pfam00378 160 SAQEALKWGLVDKVVPEDQLLDEARELAEKLAEKSPAALAQLKKALNAKLEDALPTQLEAEARLFYSTFSKDDIIEGLQA 239

                         250
                  ....*....|..
gi 503024272  248 FLEKRPPKFLGR 259
Cdd:pfam00378 240 FLEKRKPPWEDQ 251
PRK08252 PRK08252
crotonase/enoyl-CoA hydratase family protein;
1-259 7.89e-52

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181325 [Multi-domain]  Cd Length: 254  Bit Score: 169.40  E-value: 7.89e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   1 MAELCSYVIEEQIAVVTIDHPPM-NALDEATKEAIGRVFDELDqRRDELRAAILRGAGdKAFVAGADINSFLT-LTPDAA 78
Cdd:PRK08252   1 MSDEVLVERRGRVLIITINRPEArNAVNAAVAQGLAAALDELD-ADPDLSVGILTGAG-GTFCAGMDLKAFARgERPSIP 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  79 KRR-QKRTHAIVAKiedfqwPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTVRSLRHAPLGKV 157
Cdd:PRK08252  79 GRGfGGLTERPPRK------PLIAAVEGYALAGGFELALACDLIVAARDAKFGLPEVKRGLVAAGGGLLRLPRRIPYHIA 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 158 KELIFGGEMISAQEALACGLIEKVVPRGQALEAAMTLARRIAGRGPLGVAAAKKSINRARELSVAMGLESESDLWSGLCA 237
Cdd:PRK08252 153 MELALTGDMLTAERAHELGLVNRLTEPGQALDAALELAERIAANGPLAVAASKRIVVESGDWSEDEMFARQRELIAPVFT 232

                        250       260
                 ....*....|....*....|..
gi 503024272 238 TEDQKEGARAFLEKRPPKFLGR 259
Cdd:PRK08252 233 SADAKEGATAFAEKRAPVWTGK 254
PRK06494 PRK06494
enoyl-CoA hydratase; Provisional
 1-259 3.00e-51

enoyl-CoA hydratase; Provisional


Pssm-ID: 180591 [Multi-domain]  Cd Length: 259  Bit Score: 167.91  E-value: 3.00e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   1 MAELCSYVIEEQIAVVTIDHPP-MNALDEATKEAIGRVFDELdQRRDELRAAILRGAGDKAFVAGADinsfltLTPDAAK 79
Cdd:PRK06494   2 ALPFSTVERKGHVTIVTLNRPEvMNALHLDAHFELEEVFDDF-AADPEQWVAIVTGAGDKAFSAGND------LKEQAAG 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  80 RR---QKRTHAIVAKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTVRSLRHAPLGK 156
Cdd:PRK06494  75 GKrgwPESGFGGLTSRFDLDKPIIAAVNGVAMGGGFELALACDLIVAAENATFALPEPRVGLAALAGGLHRLPRQIGLKR 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 157 VKELIFGGEMISAQEALACGLIEKVVPRGQALEAAMTLARRIAGRGPLGVAAAKKSINRARELSVAMGLESESDL-W-SG 234
Cdd:PRK06494 155 AMGMILTGRRVTAREGLELGFVNEVVPAGELLAAAERWADDILACSPLSIRASKQAVYRGLEVSLEEAITAQRDYpAvEA 234

                        250       260
                 ....*....|....*....|....*
gi 503024272 235 LCATEDQKEGARAFLEKRPPKFLGR 259
Cdd:PRK06494 235 RRASQDYIEGPKAFAEKRPPRWKGR 259
PRK05980 PRK05980
crotonase/enoyl-CoA hydratase family protein;
1-256 1.39e-50

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180335 [Multi-domain]  Cd Length: 260  Bit Score: 166.47  E-value: 1.39e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   1 MAELCSYVIEEQIAVVTIDHPP-MNALDEATKEAIGRVFDELdQRRDELRAAILRGAGDKAFVAGADINSF---LTLTPD 76
Cdd:PRK05980   1 MTDTVLIEIRDGIALLTLNRPEkLNALNYALIDRLLARLDAI-EVDESVRAVILTGAGDRAFSAGADIHEFsasVAAGAD 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  77 AAKRR-QKRTHAIVAKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTVRSLRHAPLG 155
Cdd:PRK05980  80 VALRDfVRRGQAMTARLEAFPKPVIAAVNGLAFGGGCEITEAVHLAIASERALFAKPEIRLGMPPTFGGTQRLPRLAGRK 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 156 KVKELIFGGEMISAQEALACGLIEKVVPRGQALEAAMTLARRIAGRGPLGVAAAKKSINRARELSVAMGLESESDLWSGL 235
Cdd:PRK05980 160 RALELLLTGDAFSAERALEIGLVNAVVPHEELLPAARALARRIIRHSPVAVAAILTAVTRGLNLSIAEGLLIESEQFARM 239

                        250       260
                 ....*....|....*....|.
gi 503024272 236 CATEDQKEGARAFLEKRPPKF 256
Cdd:PRK05980 240 AGSADLREGLAAWIERRRPAY 260
PRK06127 PRK06127
enoyl-CoA hydratase; Provisional
 13-259 3.31e-50

enoyl-CoA hydratase; Provisional


Pssm-ID: 235705  Cd Length: 269  Bit Score: 165.65  E-value: 3.31e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  13 IAVVTIDHPP-MNALDEATKEAIGRVFDELDQRrDELRAAILRGAGDKAFVAGADINSFLTL--TPDAAKRRQKRTHAIV 89
Cdd:PRK06127  21 LGRITFNNPArHNAMSLDMWEALPQALAAAEDD-DAIRVVVLTGAGEKAFVSGADISQFEESrsDAEAVAAYEQAVEAAQ 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  90 AKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTVRSLRHAPLGKVKELIFGGEMISA 169
Cdd:PRK06127 100 AALADYAKPTIACIRGYCIGGGMGIALACDIRIAAEDSRFGIPAARLGLGYGYDGVKNLVDLVGPSAAKDLFYTARRFDA 179

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 170 QEALACGLIEKVVPRGQALEAAMTLARRIAGRGPLGVAAAKKSINRARELSVAMGLESESDLWSGLCATEDQKEGARAFL 249
Cdd:PRK06127 180 AEALRIGLVHRVTAADDLETALADYAATIAGNAPLTLRAAKRAIAELLKDEPERDMAACQALVAACFDSEDYREGRAAFM 259

                        250
                 ....*....|
gi 503024272 250 EKRPPKFLGR 259
Cdd:PRK06127 260 EKRKPVFKGR 269
PLN02600 PLN02600
enoyl-CoA hydratase
 13-259 6.25e-50

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 164.21  E-value: 6.25e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  13 IAVVTIDHPPM-NALDEATKEAIGRVFDELdQRRDELRAAILRGAGDKAFVAGADINSFLTLTPDAAKRRQKRTHAIVAK 91
Cdd:PLN02600   5 IVELRLDRPEAkNAIGKEMLRGLRSAFEKI-QADASARVVMLRSSVPGVFCAGADLKERRKMSPSEVQKFVNSLRSTFSS 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  92 IEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTVRSLRHAPLGKVKELIFGGEMISAQE 171
Cdd:PLN02600  84 LEALSIPTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPETGLAIIPGAGGTQRLPRLVGRSRAKELIFTGRRIGARE 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 172 ALACGLIEKVVPRGQALEAAMTLARRIAGRGPLGVAAAKKSINRARELSVAMGLESESDLWSGLCATEDQKEGARAFLEK 251
Cdd:PLN02600 164 AASMGLVNYCVPAGEAYEKALELAQEINQKGPLAIKMAKKAINEGSEVDMASGLEIEEECYEQVLKTKDRLEGLAAFAEK 243


                 ....*...
gi 503024272 252 RPPKFLGR 259
Cdd:PLN02600 244 RKPVYTGK 251
PRK05862 PRK05862
enoyl-CoA hydratase; Provisional
 13-259 3.67e-49

enoyl-CoA hydratase; Provisional


Pssm-ID: 180295 [Multi-domain]  Cd Length: 257  Bit Score: 162.52  E-value: 3.67e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  13 IAVVTIDHP-PMNALDEATKEAIGRVFDELDQrrDELRAAILRGAGDKAFVAGADINSFLTLT-PDAAKRRQKRTHAIVA 90
Cdd:PRK05862  14 VGLITLNRPkALNALNDALMDELGAALAAFDA--DEGIGAIVITGSEKAFAAGADIKEMADLSfMDVYKGDYITNWEKVA 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  91 KIEDfqwPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTVRSLRHAPLGKVKELIFGGEMISAQ 170
Cdd:PRK05862  92 RIRK---PVIAAVAGYALGGGCELAMMCDIIIAADTAKFGQPEIKLGVLPGMGGSQRLTRAVGKAKAMDLCLTGRMMDAA 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 171 EALACGLIEKVVPRGQALEAAMTLARRIAGRGPLGVAAAKKSINRARELSVAMGLESESDLWSGLCATEDQKEGARAFLE 250
Cdd:PRK05862 169 EAERAGLVSRVVPADKLLDEALAAATTIASFSLPAVMMAKEAVNRAYETTLAEGLLFERRLFHSLFATEDQKEGMAAFVE 248


                 ....*....
gi 503024272 251 KRPPKFLGR 259
Cdd:PRK05862 249 KRKPVFKHR 257
PRK07509 PRK07509
crotonase/enoyl-CoA hydratase family protein;
1-257 8.61e-49

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181008 [Multi-domain]  Cd Length: 262  Bit Score: 161.59  E-value: 8.61e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   1 MAELCSYVIEEQIAVVTIDHP-PMNALDEATKEAIGRVFDELDQRRDeLRAAILRGAGdKAFVAGADINSFLTLTPDAAK 79
Cdd:PRK07509   1 MMDRVSVTIEDGIADVRLNRPdKMNALDFAMFEELIATIKRLKKDRG-IRAVILSGEG-GAFCAGLDVKSVASSPGNAVK 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  80 RRQKRTHAIVakiEDFQ-----W-----PVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTVrSL 149
Cdd:PRK07509  79 LLFKRLPGNA---NLAQrvslgWrrlpvPVIAALEGVCFGGGLQIALGADIRIAAPDTKLSIMEAKWGLVPDMAGTV-SL 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 150 RH-APLGKVKELIFGGEMISAQEALACGLIEKVVPrgQALEAAMTLARRIAGRGPLGVAAAKKSINRARELSVAMGLESE 228
Cdd:PRK07509 155 RGlVRKDVARELTYTARVFSAEEALELGLVTHVSD--DPLAAALALAREIAQRSPDAIAAAKRLINRSWTASVRALLARE 232

                        250       260
                 ....*....|....*....|....*....
gi 503024272 229 SDLWSGLCATEDQKEGARAFLEKRPPKFL 257
Cdd:PRK07509 233 SVEQIRLLLGKNQKIAVKAQMKKRAPKFL 261
PRK03580 PRK03580
crotonobetainyl-CoA hydratase;
16-259 5.12e-47

crotonobetainyl-CoA hydratase;


Pssm-ID: 179599 [Multi-domain]  Cd Length: 261  Bit Score: 157.16  E-value: 5.12e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  16 VTIDHPPMNALDEATKEAIGRVFDELdqRRD-ELRAAILRGAGDKAFVAGADinsfltLTPDAAKRRQKRTHAI-----V 89
Cdd:PRK03580  16 ITLDRPKANAIDAKTSFAMGEVFLNF--RDDpELRVAIITGAGEKFFSAGWD------LKAAAEGEAPDADFGPggfagL 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  90 AKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTVRSLRHAPLGKVKELIFGGEMISA 169
Cdd:PRK03580  88 TEIFDLDKPVIAAVNGYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLPKRLPPAIANEMVMTGRRMDA 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 170 QEALACGLIEKVVPRGQALEAAMTLARRIAGRGPLGVAAAKKSINRARELSV--AMGLESESDL--WSGLCATEDQKEGA 245
Cdd:PRK03580 168 EEALRWGIVNRVVPQAELMDRARELAQQLVNSAPLAIAALKEIYRETSEMPVeeAYRYIRSGVLkhYPSVLHSEDALEGP 247

                        250
                 ....*....|....
gi 503024272 246 RAFLEKRPPKFLGR 259
Cdd:PRK03580 248 RAFAEKRDPVWKGR 261
PRK07799 PRK07799
crotonase/enoyl-CoA hydratase family protein;
10-259 1.61e-46

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181122 [Multi-domain]  Cd Length: 263  Bit Score: 156.03  E-value: 1.61e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  10 EEQIAVVTIDHPPM-NALDEATKEAIGRVFDELDQRrDELRAAILRGAGDkAFVAGADINSFLTLTP-DAAKRRQKRTHA 87
Cdd:PRK07799  12 RGHTLIVTMNRPEArNALSTEMLRIMVDAWDRVDND-PDIRSCILTGAGG-AFCAGMDLKAATKKPPgDSFKDGSYDPSR 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  88 IVAKIEDFQW--PVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTVRSLRHAPLGKVKELIFGGE 165
Cdd:PRK07799  90 IDALLKGRRLtkPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWSLFPMGGSAVRLVRQIPYTVACDLLLTGR 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 166 MISAQEALACGLIEKVVPRGQALEAAMTLARRIAGRGPLGVAAAKKSINRARELSVAMGLESESDLWSGLCATEDQKEGA 245
Cdd:PRK07799 170 HITAAEAKEIGLIGHVVPDGQALDKALELAELINANGPLAVQAILRTIRETEGMHENEAFKIDTKIGIPVFLSEDAKEGP 249

                        250
                 ....*....|....
gi 503024272 246 RAFLEKRPPKFLGR 259
Cdd:PRK07799 250 RAFAEKRAPNFQGR 263
PRK06142 PRK06142
crotonase/enoyl-CoA hydratase family protein;
9-258 1.51e-44

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235714  Cd Length: 272  Bit Score: 151.28  E-value: 1.51e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   9 IEEQIAVVTIDHP-PMNALDEATKEAIGRVFDELDqRRDELRAAILRGAGdKAFVAGADINSFLT-----LTPDAAKRRQ 82
Cdd:PRK06142  12 LADHVAQVTLNRPgKGNAMNPAFWSELPEIFRWLD-ADPEVRAVVLSGSG-KHFSYGIDLPAMAGvfgqlGKDGLARPRT 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  83 K------RTHAIVAKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTVRSLRHAPLGK 156
Cdd:PRK06142  90 DlrreilRLQAAINAVADCRKPVIAAVQGWCIGGGVDLISACDMRYASADAKFSVREVDLGMVADVGSLQRLPRIIGDGH 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 157 VKELIFGGEMISAQEALACGLIEKVVPRGQA-LEAAMTLARRIAGRGPLGVAAAKKSINRARELSVAMGLESESDLWSGL 235
Cdd:PRK06142 170 LRELALTGRDIDAAEAEKIGLVNRVYDDADAlLAAAHATAREIAAKSPLAVRGTKEVLDYMRDHRVADGLRYVATWNAAM 249

                        250       260
                 ....*....|....*....|...
gi 503024272 236 CATEDQKEGARAFLEKRPPKFLG 258
Cdd:PRK06142 250 LPSKDLTEAIAAHMEKRPPEFTG 272
PRK06143 PRK06143
enoyl-CoA hydratase; Provisional
 10-226 6.62e-42

enoyl-CoA hydratase; Provisional


Pssm-ID: 180423  Cd Length: 256  Bit Score: 143.64  E-value: 6.62e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  10 EEQIAVVTI-DHPPMNALDEATKEAIGRVFDELDQRRDeLRAAILRGAGDKAFVAGADINSFLTLTPDAAKRRQKRTHAI 88
Cdd:PRK06143  14 DRGVATLTIrNAGSLNILGTPVILALTQALRWLAADPD-VRVLVLRGAGEKAFIGGADIKEMATLDQASAEAFISRLRDL 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  89 VAKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIfPgnggtvrSLRHAPL-------GKVKELI 161
Cdd:PRK06143  93 CDAVRHFPVPVIARIPGWCLGGGLELAAACDLRIAAHDAQFGMPEVRVGI-P-------SVIHAALlprligwARTRWLL 164

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 503024272 162 FGGEMISAQEALACGLIEKVVPRGQALEAAMTLARRIAGRGPLGVAAAKKSINRARELSVAMGLE 226
Cdd:PRK06143 165 LTGETIDAAQALAWGLVDRVVPLAELDAAVERLAASLAGCGPQALRQQKRLLREWEDMPLDVAID 229
PRK09245 PRK09245
crotonase/enoyl-CoA hydratase family protein;
13-259 2.20e-40

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181723  Cd Length: 266  Bit Score: 140.11  E-value: 2.20e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  13 IAVVTIDHP-PMNAL-DEATKEAIGRVFDELdQRRDELRAAILRGAGdKAFVAGADINSFL------TLTPDAAKRRQKR 84
Cdd:PRK09245  13 IVTLTMNRPeTRNALsDNDAVDALVAACAAI-NADRSVRAVILTGAG-TAFSSGGNVKDMRarvgafGGSPADIRQGYRH 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  85 T-HAIVAKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTVRSLRHAPLGKVKELIFG 163
Cdd:PRK09245  91 GiQRIPLALYNLEVPVIAAVNGPAIGAGCDLACMCDIRIASETARFAESFVKLGLIPGDGGAWLLPRIIGMARAAEMAFT 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 164 GEMISAQEALACGLIEKVVPRGQALEAAMTLARRIAGRGPLGVAAAKKSINRARELSVAMGLESESDLWSGLCATEDQKE 243
Cdd:PRK09245 171 GDAIDAATALEWGLVSRVVPADQLLPAARALAERIAANPPHALRLTKRLLREGQHASLDTLLELSAAYQALAHHTADHRE 250

                        250
                 ....*....|....*.
gi 503024272 244 GARAFLEKRPPKFLGR 259
Cdd:PRK09245 251 AVDAFLEKRPPVFTGR 266
PRK06563 PRK06563
crotonase/enoyl-CoA hydratase family protein;
23-259 3.68e-40

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180625 [Multi-domain]  Cd Length: 255  Bit Score: 139.33  E-value: 3.68e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  23 MNALDEATKEAIGRVFDELDqRRDELRAAILRGAGDKaFVAGADINSF-------LTLTPDAA--------KRRQKrtha 87
Cdd:PRK06563  20 RNAFDSAMLDDLALALGEYE-ADDELRVAVLFAHGEH-FTAGLDLADVapklaagGFPFPEGGidpwgtvgRRLSK---- 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  88 ivakiedfqwPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTVRSLRHAPLGKVKELIFGGEMI 167
Cdd:PRK06563  94 ----------PLVVAVQGYCLTLGIELMLAADIVVAADNTRFAQLEVQRGILPFGGATLRFPQAAGWGNAMRYLLTGDEF 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 168 SAQEALACGLIEKVVPRGQALEAAMTLARRIAGRGPLGVAAAKKSINRARELSVAMGLESESDLWSGLCATEDQKEGARA 247
Cdd:PRK06563 164 DAQEALRLGLVQEVVPPGEQLERAIELAERIARAAPLGVQATLASARAAVREGEAAAAAQLPPELRPLFTSEDAKEGVQA 243

                        250
                 ....*....|..
gi 503024272 248 FLEKRPPKFLGR 259
Cdd:PRK06563 244 FLERRPARFKGR 255
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
4-252 5.25e-40

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181254  Cd Length: 255  Bit Score: 139.00  E-value: 5.25e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   4 LCSYVIEEQIAVVTIDHPPM-NALDEATKEAIGRVFDELDqrrDELRAAILRGAGDKaFVAGADINSFLTLTPDAAKRRQ 82
Cdd:PRK08150   3 LVSYELDGGVATIGLNRPAKrNALNDGLIAALRAAFARLP---EGVRAVVLHGEGDH-FCAGLDLSELRERDAGEGMHHS 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  83 KRTHAIVAKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTVRSLRHAPLGKVKELIF 162
Cdd:PRK08150  79 RRWHRVFDKIQYGRVPVIAALHGAVVGGGLELASAAHIRVADESTYFALPEGQRGIFVGGGGSVRVPRLIGVARMTDMML 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 163 GGEMISAQEALACGLIEKVVPRGQALEAAMTLARRIAGRGPLGVAAAKKSINRARELSVAMGLESESdLWSGLCATE-DQ 241
Cdd:PRK08150 159 TGRVYDAQEGERLGLAQYLVPAGEALDKAMELARRIAQNAPLTNFAVLNALPRIADMSADDGLFVES-LMAAVAQSApEA 237

                        250
                 ....*....|.
gi 503024272 242 KEGARAFLEKR 252
Cdd:PRK08150 238 KERLRAFLEKK 248
PRK11423 PRK11423
methylmalonyl-CoA decarboxylase; Provisional
 8-259 1.61e-38

methylmalonyl-CoA decarboxylase; Provisional


Pssm-ID: 236908 [Multi-domain]  Cd Length: 261  Bit Score: 135.15  E-value: 1.61e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   8 VIEEQIAVVTIDHPP-MNALDEATKEAIGRVFDELdqRRDELRAAILR-GAGDKAFVAGADINSFltltpdAAKRR---- 81
Cdd:PRK11423   9 VTINKIATITFNNPAkRNALSKVLIDDLMQALSDL--NRPEIRVVILRaPSGSKVWSAGHDIHEL------PSGGRdpls 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  82 -QKRTHAIVAKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIfPGN-GGTVRSLRHAPLGKVKE 159
Cdd:PRK11423  81 yDDPLRQILRMIQKFPKPVIAMVEGSVWGGAFELIMSCDLIIAASTSTFAMTPANLGV-PYNlSGILNFTNDAGFHIVKE 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 160 LIFGGEMISAQEALACGLIEKVVPRGQALEAAMTLARRIAGRGPLGVAAAKKSI---NRARELSVAMgLESESDLWSGLC 236
Cdd:PRK11423 160 MFFTASPITAQRALAVGILNHVVEVEELEDFTLQMAHHISEKAPLAIAVIKEQLrvlGEAHPMNPDE-FERIQGLRRAVY 238

                        250       260
                 ....*....|....*....|...
gi 503024272 237 ATEDQKEGARAFLEKRPPKFLGR 259
Cdd:PRK11423 239 DSEDYQEGMNAFLEKRKPVFVGH 261
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
8-221 1.96e-37

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 139.26  E-value: 1.96e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   8 VIEEQIAVVTIDHP--PMNALDEATKEAIGRVFDELdQRRDELRAAILRGAGDKAFVAGADINsFLTLTPDAAKRRQ--K 83
Cdd:PRK11154  11 VREDNIAVITIDVPgeKMNTLKAEFAEQVRAILKQL-REDKELKGVVFISGKPDNFIAGADIN-MLAACKTAQEAEAlaR 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  84 RTHAIVAKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYA--EEQSRFGFPEVNLAIFPGNGGTVRSLRHAPLGKVKELI 161
Cdd:PRK11154  89 QGQQLFAEIEALPIPVVAAIHGACLGGGLELALACHYRVCtdDPKTVLGLPEVQLGLLPGSGGTQRLPRLIGVSTALDMI 168

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 162 FGGEMISAQEALACGLIEKVVPRGQALEAAmtlarriagrgplgVAAAKKSINRARELSV 221
Cdd:PRK11154 169 LTGKQLRAKQALKLGLVDDVVPHSILLEVA--------------VELAKKGKPARRPLPV 214
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
 10-230 1.37e-36

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 130.09  E-value: 1.37e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  10 EEQIAVVTIDHP-PMNALDEATKEAIGRVFDELDQRrDELRAAILRGAgDKAFVAGADINSFLTLTPdaAKRRQKRTHAI 88
Cdd:PRK06190  11 HDRVRTLTLNRPeARNALSAALRRALFAALAEADAD-DDVDVVVLTGA-DPAFCAGLDLKELGGDGS--AYGAQDALPNP 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  89 VAKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTVRSLRHAPLGKVKELIFGGEMIS 168
Cdd:PRK06190  87 SPAWPAMRKPVIGAINGAAVTGGLELALACDILIASERARFADTHARVGILPGWGLSVRLPQKVGIGRARRMSLTGDFLD 166

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 503024272 169 AQEALACGLIEKVVPRGQALEAAMTLARRIAGRGPLGVAAAKKSINRARELSVAMGLESESD 230
Cdd:PRK06190 167 AADALRAGLVTEVVPHDELLPRARRLAASIAGNNPAAVRALKASYDDGAAAQTGDALALEAE 228
PRK08260 PRK08260
enoyl-CoA hydratase; Provisional
 7-259 8.97e-35

enoyl-CoA hydratase; Provisional


Pssm-ID: 236206 [Multi-domain]  Cd Length: 296  Bit Score: 126.27  E-value: 8.97e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   7 YVIEEQIAVVTIDHPP-MNALDEATKEAIGRVFDELDqRRDELRAAILRGAGdKAFVAGADI----NSF-----LTLTPD 76
Cdd:PRK08260   8 YDVADGIATITLNRPDkLNAFTVTMARELIEAFDAAD-ADDAVRAVIVTGAG-RAFCAGADLsaggNTFdldapRTPVEA 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  77 AAKRRQKRTHAIV--------AKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTVRS 148
Cdd:PRK08260  86 DEEDRADPSDDGVrdgggrvtLRIFDSLKPVIAAVNGPAVGVGATMTLAMDIRLASTAARFGFVFGRRGIVPEAASSWFL 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 149 LRHAPLGKVKELIFGGEMISAQEALACGLIEKVVPRGQALEAAMTLARRIA-GRGPLGVAAAKKSINRARELSVAMG--- 224
Cdd:PRK08260 166 PRLVGLQTALEWVYSGRVFDAQEALDGGLVRSVHPPDELLPAARALAREIAdNTSPVSVALTRQMMWRMAGADHPMEahr 245

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 503024272 225 LESESDLWSGLCAteDQKEGARAFLEKRPPKFLGR 259
Cdd:PRK08260 246 VDSRAIYSRGRSG--DGKEGVSSFLEKRPAVFPGK 278
fadB PRK11730
fatty acid oxidation complex subunit alpha FadB;
9-201 1.30e-34

fatty acid oxidation complex subunit alpha FadB;


Pssm-ID: 183293 [Multi-domain]  Cd Length: 715  Bit Score: 131.14  E-value: 1.30e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   9 IEEQIAVVTIDHP-PMNALDEATKEAIGRVFDELDQRRDeLRAAILRGAGDkAFVAGADINSFLTL-TPDAAKRRQ--KR 84
Cdd:PRK11730  13 LEDGIAELVFDAPgSVNKLDRATLASLGEALDALEAQSD-LKGLLLTSAKD-AFIVGADITEFLSLfAAPEEELSQwlHF 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  85 THAIVAKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTVRSLRHAPLGKVKELIFGG 164
Cdd:PRK11730  91 ANSIFNRLEDLPVPTVAAINGYALGGGCECVLATDYRVASPDARIGLPETKLGIMPGFGGTVRLPRLIGADNALEWIAAG 170

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 503024272 165 EMISAQEALACGLIEKVVPRGQALEAAMTLARR-IAGR 201
Cdd:PRK11730 171 KDVRAEDALKVGAVDAVVAPEKLQEAALALLKQaIAGK 208
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
 10-259 1.94e-34

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 124.65  E-value: 1.94e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  10 EEQIAVVTIDHPPM-NALDEATKEAIGRVFDELDqRRDELRAAILRGAGdKAFVAGADINSF---LTLTPDAAKRRQKRT 85
Cdd:PRK05995  11 RGQVATVTLNRPDVrNAFNETVIAELTAAFRALD-ADDSVRAVVLAGAG-KAFCAGADLNWMkkmAGYSDDENRADARRL 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  86 HAIVAKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPgngGTVRS--LRHAPLGKVKELIFG 163
Cdd:PRK05995  89 ADMLRAIYRCPKPVIARVHGDAYAGGMGLVAACDIAVAADHAVFCLSEVRLGLIP---ATISPyvIRAMGERAARRYFLT 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 164 GEMISAQEALACGLIEKVVPrGQALEAAMT-LARRIAGRGPLGVAAAKKSIN--RARELSVAMGLESESDLwSGLCATED 240
Cdd:PRK05995 166 AERFDAAEALRLGLVHEVVP-AEALDAKVDeLLAALVANSPQAVRAGKRLVRdvAGRPIDAALIADTASRI-ALIRATEE 243

                        250
                 ....*....|....*....
gi 503024272 241 QKEGARAFLEKRPPKFLGR 259
Cdd:PRK05995 244 AREGVAAFLEKRKPAWRGR 262
PRK07938 PRK07938
enoyl-CoA hydratase family protein;
6-214 3.11e-34

enoyl-CoA hydratase family protein;


Pssm-ID: 181174  Cd Length: 249  Bit Score: 123.54  E-value: 3.11e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   6 SYVIEEQIAVVTIDHPPMNALDEATKEAIGRVFDELDqRRDELRAAILRGAGdKAFVAGADINSfLTLTPD-----AAKR 80
Cdd:PRK07938   5 STTPEPGIAEVTVDYPPVNALPSAGWFALADAITAAG-ADPDTRVVVLRAEG-RGFNAGVDIKE-LQATPGftaliDANR 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  81 RqkrTHAIVAKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFpgnGGTVRSLRHAPLGKVKEL 160
Cdd:PRK07938  82 G---CFAAFRAVYECAVPVIAAVHGFCLGGGIGLVGNADVIVASDDATFGLPEVDRGAL---GAATHLQRLVPQHLMRAL 155

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 503024272 161 IFGGEMISAQEALACGLIEKVVPRGQALEAAMTLARRIAGRGPLGVAAAKKSIN 214
Cdd:PRK07938 156 FFTAATITAAELHHFGSVEEVVPRDQLDEAALEVARKIAAKDTRVIRAAKEALN 209
PRK07511 PRK07511
enoyl-CoA hydratase; Provisional
 10-256 2.11e-33

enoyl-CoA hydratase; Provisional


Pssm-ID: 181009 [Multi-domain]  Cd Length: 260  Bit Score: 121.64  E-value: 2.11e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  10 EEQIAVVTIDHPPM-NALDEATKEAIGRVFDELdQRRDELRAAILRGAGDkAFVAGADINSFLTL-TPDAAKRRQK--RT 85
Cdd:PRK07511  10 EGSTLVLTLSNPGArNALHPDMYAAGIEALNTA-ERDPSIRAVVLTGAGG-FFCAGGNLNRLLENrAKPPSVQAASidGL 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  86 HAIVAKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTVRSLRHAPLGKVKELIFGGE 165
Cdd:PRK07511  88 HDWIRAIRAFPKPVIAAVEGAAAGAGFSLALACDLLVAARDAKFVMAYVKVGLTPDGGGSWFLARALPRQLATELLLEGK 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 166 MISAQEALACGLIEKVVPRGQALEAAMTLARRIAGRGPLGVAAAKKSINRARELSVAMGLESESDLWSGLCATEDQKEGA 245
Cdd:PRK07511 168 PISAERLHALGVVNRLAEPGQALAEALALADQLAAGSPNALARIKSLIADAPEATLAAQLEAERDHFVASLHHADALEGI 247

                        250
                 ....*....|.
gi 503024272 246 RAFLEKRPPKF 256
Cdd:PRK07511 248 AAFLEKRAPDY 258
PRK06072 PRK06072
enoyl-CoA hydratase; Provisional
 11-259 2.40e-33

enoyl-CoA hydratase; Provisional


Pssm-ID: 168377 [Multi-domain]  Cd Length: 248  Bit Score: 121.42  E-value: 2.40e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  11 EQIAVVTIDHP-PMNALDEATKEAIGRVFDELDqRRDELRAAILRGAGdKAFVAGADINSFltlTPDAAKRRQKRTHAIV 89
Cdd:PRK06072   8 EGYAIVTMSRPdKLNALNLEMRNEFISKLKQIN-ADPKIRVVIVTGEG-RAFCVGADLSEF---APDFAIDLRETFYPII 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  90 AKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTVRSLRHAPLGKVKELIFGGEmISA 169
Cdd:PRK06072  83 REIRFSDKIYISAINGVTAGACIGIALSTDFKFASRDVKFVTAFQRLGLASDTGVAYFLLKLTGQRFYEILVLGGE-FTA 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 170 QEALACGLIEKVV-PRGQALEaamtLARRIAGrGP-LGVAAAKKSINRARELSVAMGLESESDLWSGLCATEDQKEGARA 247
Cdd:PRK06072 162 EEAERWGLLKISEdPLSDAEE----MANRISN-GPfQSYIAAKRMINLVLYNDLEEFLEYESAIQGYLGKTEDFKEGISS 236

                        250
                 ....*....|..
gi 503024272 248 FLEKRPPKFLGR 259
Cdd:PRK06072 237 FKEKREPKFKGI 248
PRK08139 PRK08139
enoyl-CoA hydratase; Validated
 13-259 1.17e-31

enoyl-CoA hydratase; Validated


Pssm-ID: 181249  Cd Length: 266  Bit Score: 117.35  E-value: 1.17e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  13 IAVVTIDHPP-MNALDEATKEAIGRVFDELDqRRDELRAAILRGAGdKAFVAGADINSfLTLTPDAA--KRRQKRTHAIV 89
Cdd:PRK08139  21 VATLTLNRPQaFNALSEAMLAALQAALDAIA-ADPSVRVVVLAAAG-KAFCAGHDLKE-MRAARGLAyfRALFARCSRVM 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  90 AKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIF---PGnggtVRSLRHAPLGKVKELIFGGEM 166
Cdd:PRK08139  98 QAIVALPQPVIARVHGIATAAGCQLVASCDLAVAADTARFAVPGVNIGLFcstPM----VALSRNVPRKQAMEMLLTGEF 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 167 ISAQEALACGLIEKVVPRGQALEAAMTLARRIAGRGPLGVAAAKKSINRARElsvaMGLESESDLWSGLCA----TEDQK 242
Cdd:PRK08139 174 IDAATAREWGLVNRVVPADALDAAVARLAAVIAAKSPAAVRIGKEAFYRQAE----MPLADAYAYAGDVMAenmmAEDAE 249

                        250
                 ....*....|....*..
gi 503024272 243 EGARAFLEKRPPKFLGR 259
Cdd:PRK08139 250 EGIDAFLEKRPPEWRGR 266
PLN02664 PLN02664
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase
 24-256 1.35e-31

enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase


Pssm-ID: 178269 [Multi-domain]  Cd Length: 275  Bit Score: 117.31  E-value: 1.35e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  24 NALDEATKEAIGRVFDELDQRRDeLRAAILRGAGDKaFVAGADINSFLTLTPDAA-----------KRRQKRTHAIVAKI 92
Cdd:PLN02664  30 NALSLDFFTEFPKALSSLDQNPN-VSVIILSGAGDH-FCSGIDLKTLNSISEQSSsgdrgrsgerlRRKIKFLQDAITAI 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  93 EDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTVRSLRHAPLGKVKELIFGGEMISAQEA 172
Cdd:PLN02664 108 EQCRKPVIAAIHGACIGGGVDIVTACDIRYCSEDAFFSVKEVDLAITADLGTLQRLPSIVGYGNAMELALTGRRFSGSEA 187

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 173 LACGLIEKVVPRGQAL-EAAMTLARRIAGRGPLGVAAAKKSINRARELSVAMGLESESDLWSGLCATEDQKEGARAFLEK 251
Cdd:PLN02664 188 KELGLVSRVFGSKEDLdEGVRLIAEGIAAKSPLAVTGTKAVLLRSRELSVEQGLDYVATWNSAMLVSDDLNEAVSAQIQK 267


                 ....*
gi 503024272 252 RPPKF 256
Cdd:PLN02664 268 RKPVF 272
PRK08290 PRK08290
enoyl-CoA hydratase; Provisional
 1-227 3.40e-30

enoyl-CoA hydratase; Provisional


Pssm-ID: 236220 [Multi-domain]  Cd Length: 288  Bit Score: 113.90  E-value: 3.40e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   1 MAELCSYVIEEQIAVVTIDHPPM-NALDEATKEAIGRVFDELDQRrDELRAAILRGAGdKAFVAGADINSFLTLTPDAAK 79
Cdd:PRK08290   2 EYEYVRYEVAGRIARITLNRPEArNAQNRQMLYELDAAFRRAEAD-DAVRVIVLAGAG-KHFSAGHDLGSGTPGRDRDPG 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  80 RRQKRT----HAIVAKIE------------------DFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLA 137
Cdd:PRK08290  80 PDQHPTlwwdGATKPGVEqryarewevylgmcrrwrDLPKPTIAQVQGACIAGGLMLAWVCDLIVASDDAFFSDPVVRMG 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 138 IfPGnggtVRSLRHA-PLG--KVKELIFGGEMISAQEALACGLIEKVVPRGQALEAAMTLARRIAGRGPLGVAAAKKSIN 214
Cdd:PRK08290 160 I-PG----VEYFAHPwELGprKAKELLFTGDRLTADEAHRLGMVNRVVPRDELEAETLELARRIAAMPPFGLRLTKRAVN 234

                        250
                 ....*....|...
gi 503024272 215 RARElsvAMGLES 227
Cdd:PRK08290 235 QTLD---AQGFRA 244
PRK08259 PRK08259
crotonase/enoyl-CoA hydratase family protein;
13-200 7.01e-30

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236205  Cd Length: 254  Bit Score: 112.30  E-value: 7.01e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  13 IAVVTIDHPPM-NALDEATKEAIGRVFDELDqRRDELRAAILRGAGDkAFVAGADINSFltltpdaAKRRQKRTHA---- 87
Cdd:PRK08259  13 VTTVILNRPEVrNAVDGPTAAALADAFRAFD-ADDAASVAVLWGAGG-TFCAGADLKAV-------GTGRGNRLHPsgdg 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  88 -------IVAKiedfqwPVIAAIDGFCLGGGLELALCCDVRYAEEQS-------RFGFPEVNlaifpgnGGTVRSLRHAP 153
Cdd:PRK08259  84 pmgpsrmRLSK------PVIAAVSGYAVAGGLELALWCDLRVAEEDAvfgvfcrRWGVPLID-------GGTVRLPRLIG 150

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 503024272 154 LGKVKELIFGGEMISAQEALACGLIEKVVPRGQALEAAMTLARRIAG 200
Cdd:PRK08259 151 HSRAMDLILTGRPVDADEALAIGLANRVVPKGQARAAAEELAAELAA 197
PRK08258 PRK08258
enoyl-CoA hydratase family protein;
9-259 1.96e-29

enoyl-CoA hydratase family protein;


Pssm-ID: 181329  Cd Length: 277  Bit Score: 111.60  E-value: 1.96e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   9 IEEQIAVVTIDHPP-MNALdeaTKEAIGRV---FDELdQRRDELRAAILRGAGDkAFVAGAD----INSFLTLTPDAAKR 80
Cdd:PRK08258  23 VDDGVATITLNRPErKNPL---TFESYAELrdlFREL-VYADDVKAVVLTGAGG-NFCSGGDvheiIGPLTKMDMPELLA 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  81 RQKRTHAIVAKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFG--FPEVNLA--------IFPgnggtvrslR 150
Cdd:PRK08258  98 FTRMTGDLVKAMRACPQPIIAAVDGVCAGAGAILAMASDLRLGTPSAKTAflFTRVGLAgadmgacaLLP---------R 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 151 HAPLGKVKELIFGGEMISAQEALACGLIEKVVPRGQALEAAMTLARRIAgRGP-LGVAAAKKSINRARELSVAMGLESES 229
Cdd:PRK08258 169 IIGQGRASELLYTGRSMSAEEGERWGFFNRLVEPEELLAEAQALARRLA-AGPtFAHGMTKTMLHQEWDMGLEEAIEAEA 247

                        250       260       270
                 ....*....|....*....|....*....|
gi 503024272 230 DLWSGLCATEDQKEGARAFLEKRPPKFLGR 259
Cdd:PRK08258 248 QAQAICMQTEDFRRAYEAFVAKRKPVFEGD 277
PRK05869 PRK05869
enoyl-CoA hydratase; Validated
 13-219 3.42e-29

enoyl-CoA hydratase; Validated


Pssm-ID: 235632 [Multi-domain]  Cd Length: 222  Bit Score: 109.93  E-value: 3.42e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  13 IAVVTIDHPPMNALDEATKEAIGRVFDELDqRRDELRAAILRGaGDKAFVAGADINSFLTLTPD---AAKRRQKRTHAIV 89
Cdd:PRK05869  18 LATLLLSRPPTNALTRQVYREIVAAANELG-RRDDVAAVILYG-GHEIFSAGDDMPELRTLSAQeadTAARVRQQAVDAV 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  90 AKIEDfqwPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTVRSLRHAPLGKVKELIFGGEMISA 169
Cdd:PRK05869  96 AAIPK---PTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILAGLAPSGDGMARLTRAAGPSRAKELVFSGRFFDA 172

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 503024272 170 QEALACGLIEKVVPRGQALEAAMTLARRIAGRGPLGVAAAKKSINRAREL 219
Cdd:PRK05869 173 EEALALGLIDEMVAPDDVYDAAAAWARRFLDGPPHALAAAKAGISDVYEL 222
PRK05981 PRK05981
enoyl-CoA hydratase/isomerase;
13-259 6.96e-29

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235661  Cd Length: 266  Bit Score: 110.21  E-value: 6.96e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  13 IAVVTIDHPP-MNALDEATKEAIGRVFDELDQRRDELRAAILRGAGdKAFVAGADI------NSFLTLTPDAAKRRQKRT 85
Cdd:PRK05981  14 VAILTLDHPEvMNAVSIDMLGGLAEALDAIEDGKAEVRCLVLTGAG-RGFCTGANLqgrgsgGRESDSGGDAGAALETAY 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  86 HAIVAKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRF--GFPEVNLAifPGNGGTVRSLRhaPLGKVK--ELI 161
Cdd:PRK05981  93 HPFLRRLRNLPCPIVTAVNGPAAGVGMSFALMGDLILCARSAYFlqAFRRIGLV--PDGGSTWLLPR--LVGKARamELS 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 162 FGGEMISAQEALACGLIEKVVPRGQALEAAMTLARRIAgRGP-LGVAAAKKSINRARELSVAMGLESESDLWSGLCATED 240
Cdd:PRK05981 169 LLGEKLPAETALQWGLVNRVVDDAELMAEAMKLAHELA-NGPtVALGLIRKLYWDSPENDFEEQLNLEREAQRIAGKTED 247

                        250
                 ....*....|....*....
gi 503024272 241 QKEGARAFLEKRPPKFLGR 259
Cdd:PRK05981 248 FKEGVGAFLQKRPAQFKGR 266
PRK06210 PRK06210
enoyl-CoA hydratase; Provisional
 8-259 1.11e-28

enoyl-CoA hydratase; Provisional


Pssm-ID: 180472  Cd Length: 272  Bit Score: 109.79  E-value: 1.11e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   8 VIEEQIAVVTIDHPP-MNALDEATKEAIGRVFDELDqRRDELRAAILRGAGdKAFVAGADINSFLTLTPDAAKRRQKRTH 86
Cdd:PRK06210  11 VADSGVAVITLNRPDrLNAWTPVMEAEVYAAMDRAE-ADPAVRVIVLTGAG-RGFCAGADMGELQTIDPSDGRRDTDVRP 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  87 AIVAKIEDFQW----------PVIAAIDGFCLGGGLELALCCDVRYAEEQSRF--GFPEVNLA-------IFPgnggtvr 147
Cdd:PRK06210  89 FVGNRRPDYQTryhfltalrkPVIAAINGACAGIGLTHALMCDVRFAADGAKFttAFARRGLIaehgiswILP------- 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 148 slRHAPLGKVKELIFGGEMISAQEALACGLIEKVVPRGQALEAAMTLARRIAGR-GPLGVAAAKKSINRARELSVAMGLE 226
Cdd:PRK06210 162 --RLVGHANALDLLLSARTFYAEEALRLGLVNRVVPPDELMERTLAYAEDLARNvSPASMAVIKRQLYEDAFQTLAEATA 239

                        250       260       270
                 ....*....|....*....|....*....|...
gi 503024272 227 SESDLWSGLCATEDQKEGARAFLEKRPPKFLGR 259
Cdd:PRK06210 240 RANREMHESLQRPDFIEGVASFLEKRPPRFPGL 272
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
 1-259 4.16e-28

enoyl-CoA hydratase; Provisional


Pssm-ID: 236163  Cd Length: 262  Bit Score: 108.08  E-value: 4.16e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   1 MAELCSYVIEEQIAVVTIDHPP-MNALDEATKEAIGRVFDELdqRRDELRAAILRGAGdKAFVAGADINSfLTLTPDAAK 79
Cdd:PRK08140   2 MYETILLAIEAGVATLTLNRPDkLNSFTREMHRELREALDQV--EDDGARALLLTGAG-RGFCAGQDLAD-RDVTPGGAM 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  80 RR-----QKRTHAIVAKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTVRSLRHAPL 154
Cdd:PRK08140  78 PDlgesiETFYNPLVRRLRALPLPVIAAVNGVAAGAGANLALACDIVLAARSASFIQAFVKIGLVPDSGGTWFLPRLVGM 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 155 GKVKELIFGGEMISAQEALACGLIEKVVPRGQALEAAMTLARRIAGRGPLGVAAAKKSINRARELSVAMGLESESDLWSG 234
Cdd:PRK08140 158 ARALGLALLGEKLSAEQAEQWGLIWRVVDDAALADEAQQLAAHLATQPTRGLALIKQAMNASATNTLDAQLDLERDLQRE 237

                        250       260
                 ....*....|....*....|....*
gi 503024272 235 LCATEDQKEGARAFLEKRPPKFLGR 259
Cdd:PRK08140 238 AGRSADYAEGVSAFLEKRAPRFTGR 262
PRK07659 PRK07659
enoyl-CoA hydratase; Provisional
 7-259 3.60e-27

enoyl-CoA hydratase; Provisional


Pssm-ID: 236073 [Multi-domain]  Cd Length: 260  Bit Score: 105.50  E-value: 3.60e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   7 YVIEEQIAVVTIDHP-PMNALDEATKEAIGRVFDELDQRrdELRAAILRGAGdKAFVAGADINSFLTLT-PDAAKRRQKR 84
Cdd:PRK07659  10 VKYEGRVATIMLNRPeALNALDEPMLKELLQALKEVAES--SAHIVVLRGNG-RGFSAGGDIKMMLSSNdESKFDGVMNT 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  85 THAIVAKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTVRSLRHAPLGKVKELIFGG 164
Cdd:PRK07659  87 ISEIVVTLYTMPKLTISAIHGPAAGLGLSIALTADYVIADISAKLAMNFIGIGLIPDGGGHFFLQKRVGENKAKQIIWEG 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 165 EMISAQEALACGLIEKVVPRGQALEAAMTLARRIAGrgPLGVAAAKKSI----NRARELSVamgLESESDLWSGLCATED 240
Cdd:PRK07659 167 KKLSATEALDLGLIDEVIGGDFQTAAKQKISEWLQK--PLKAMIETKQIycelNRSQLEQV---LQLEKRAQYAMRQTAD 241

                        250
                 ....*....|....*....
gi 503024272 241 QKEGARAFLEKRPPKFLGR 259
Cdd:PRK07659 242 HKEGIRAFLEKRLPVFKGE 260
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
 6-219 5.30e-27

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 109.54  E-value: 5.30e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272    6 SYVIEEQIAVVTIDHP--PMNALDEATKEAIGRVFDELdQRRDELRAAILRGAGDKAFVAGADINSFLTL-TPDAAKRRQ 82
Cdd:TIGR02441  16 HYEVKGDVAVVKIDSPnsKVNTLSKELFAEFKEVMNEL-WTNEAIKSAVLISGKPGSFVAGADIQMIAACkTAQEVTQLS 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   83 KRTHAIVAKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYA--EEQSRFGFPEVNLAIFPGNGGTVRSLRHAPLGKVKEL 160
Cdd:TIGR02441  95 QEGQEMFERIEKSQKPIVAAISGSCLGGGLELALACHYRIAtkDRKTLLGLPEVMLGLLPGAGGTQRLPKLTGVPAALDM 174

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 503024272  161 IFGGEMISAQEALACGLIEKVV-PRGQALEAA----MTLARRIAGRGPLGVAAAKKSINRAREL 219
Cdd:TIGR02441 175 MLTGKKIRADRAKKMGIVDQLVdPLGPGLKPAeentIEYLEEVAVKFAQGLANGKLSINRDKGL 238
PRK09120 PRK09120
p-hydroxycinnamoyl CoA hydratase/lyase; Validated
 9-252 8.90e-27

p-hydroxycinnamoyl CoA hydratase/lyase; Validated


Pssm-ID: 236383  Cd Length: 275  Bit Score: 104.71  E-value: 8.90e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   9 IEEQIAVVTIDHP-PMNALDEATKEAIGRVFDELDQRrDELRAAILRGAGDkAFVAGADINSFLTLT---PDAAKRRQKR 84
Cdd:PRK09120  14 VEDGIAWVTLNRPeKRNAMSPTLNREMIDVLDALEFD-DDAGVLVLTGAGD-AWSAGMDLKEYFRETdaqPEILQERIRR 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  85 thaivakiEDFQW---------PVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGT-----VRSLR 150
Cdd:PRK09120  92 --------EAYGWwrrlrwyqkPTIAMVNGWCFGGGFSPLVACDLAIAADEAQFGLSEINWGIPPGGGVSkamadTVGHR 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 151 HAPLgkvkeLIFGGEMISAQEALACGLIEKVVPRGQALEAAMTLARRIAGRGPLGVAAAKKSINRARELS--------VA 222
Cdd:PRK09120 164 DALY-----YIMTGETFTGRKAAEMGLVNESVPLAQLRARTRELAAKLLEKNPVVLRAAKDGFKRVRELTwdqaedylYA 238

                        250       260       270
                 ....*....|....*....|....*....|
gi 503024272 223 MGLESESdlwsgLCATEDQKEGARAFLEKR 252
Cdd:PRK09120 239 KLEQANS-----LDPEGGREEGLKQFLDDK 263
PRK07854 PRK07854
enoyl-CoA hydratase; Provisional
 9-259 5.61e-26

enoyl-CoA hydratase; Provisional


Pssm-ID: 236115 [Multi-domain]  Cd Length: 243  Bit Score: 101.64  E-value: 5.61e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   9 IEEQIAVVTIDHPPM-NALD----EATKEAIGRVFDEldqrrdELRAAILRGAGdKAFVAGADinsfLTLTPDAAKRRQK 83
Cdd:PRK07854   6 RDGQVLTIELQRPERrNALNaelcEELREAVRKAVDE------SARAIVLTGQG-TVFCAGAD----LSGDVYADDFPDA 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  84 RTHAIVAkIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNgGTVRslRHAPL---GKVKEL 160
Cdd:PRK07854  75 LIEMLHA-IDAAPVPVIAAINGPAIGAGLQLAMACDLRVVAPEAYFQFPVAKYGIALDN-WTIR--RLSSLvggGRARAM 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 161 IFGGEMISAQEALACGLIEKVVPRGQALEaamtLARRIAGRGPLGVAAAKKSINRARelSVAMGLESESDLWSGLCATED 240
Cdd:PRK07854 151 LLGAEKLTAEQALATGMANRIGTLADAQA----WAAEIAGLAPLALQHAKRVLNDDG--AIEEAWPAHKELFDKAWASQD 224

                        250
                 ....*....|....*....
gi 503024272 241 QKEGARAFLEKRPPKFLGR 259
Cdd:PRK07854 225 AIEAQVARIEKRPPKFQGA 243
PLN02888 PLN02888
enoyl-CoA hydratase
 13-255 2.75e-25

enoyl-CoA hydratase


Pssm-ID: 215480  Cd Length: 265  Bit Score: 100.60  E-value: 2.75e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  13 IAVVTIDHP-PMNALDEATKEAIGRVFDELDQRrDELRAAILRGAGdKAFVAGADinsfLTLTPDAAKRRQKRTHA-IVA 90
Cdd:PLN02888  20 IATITINRPkALNALTRPMMVELAAAFKRLDED-DSVKVIILTGSG-RAFCSGVD----LTAAEEVFKGDVKDVETdPVA 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  91 KIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTVRSLRHAPLGKVKELIFGGEMISAQ 170
Cdd:PLN02888  94 QMERCRKPIIGAINGFAITAGFEIALACDILVASRGAKFIDTHAKFGIFPSWGLSQKLSRIIGANRAREVSLTAMPLTAE 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 171 EALACGLIEKVVPRGQALEAAMTLARRIAGRGPLGVAAAKKSINRARELSVAMGLESES----DLWSGLcaTEDQKEGAR 246
Cdd:PLN02888 174 TAERWGLVNHVVEESELLKKAREVAEAIIKNNQGMVLRYKSVINDGLKLDLGHALQLEKerahDYYNGM--TKEQFQKMQ 251

                        250
                 ....*....|...
gi 503024272 247 AFLE----KRPPK 255
Cdd:PLN02888 252 EFIAgrssKKPSK 264
PRK08788 PRK08788
enoyl-CoA hydratase; Validated
 100-222 9.21e-21

enoyl-CoA hydratase; Validated


Pssm-ID: 236338  Cd Length: 287  Bit Score: 88.82  E-value: 9.21e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 100 IAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTVRSLRHAPLGKVKELIFGGEMISAQEALACGLIE 179
Cdd:PRK08788 125 IALVQGDALGGGFEAALSHHTIIAERGAKMGFPEILFNLFPGMGAYSFLARRVGPKLAEELILSGKLYTAEELHDMGLVD 204

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 503024272 180 KVVPRGQALEAAMTLARRIAGRgPLGVAAAKKSINRARELSVA 222
Cdd:PRK08788 205 VLVEDGQGEAAVRTFIRKSKRK-LNGWRAMLRARRRVNPLSLE 246
PLN02921 PLN02921
naphthoate synthase
 9-256 6.63e-20

naphthoate synthase


Pssm-ID: 178509 [Multi-domain]  Cd Length: 327  Bit Score: 87.15  E-value: 6.63e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   9 IEEQIAVVTIDHPP-MNALDEATKEAIGRVFDelDQRRD-ELRAAILRGAGDKAFVAGADiNSFLT----LTPDAAKRRq 82
Cdd:PLN02921  73 VGEGIAKITINRPErRNAFRPRTVKELQRAFN--DARDDsSVGVIILTGKGTKAFCSGGD-QAVRGkdgyVGPDDAGRL- 148

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  83 kRTHAIVAKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTVRSLRHAPLGKVKELIF 162
Cdd:PLN02921 149 -NVLDLQIQIRRLPKPVIAMVAGYAVGGGHILHMVCDLTIAADNAVFGQTGPKVGSFDAGYGSSIMARLVGQKKAREMWF 227

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 163 GGEMISAQEALACGLIEKVVPRGQALEAAMTLARRIAGRGPLGVAAAKKSINRARELSVamGLE----SESDLWSGlcaT 238
Cdd:PLN02921 228 LARFYTASEALKMGLVNTVVPLDELEGETVKWCREILRNSPTAIRVLKSALNAADDGHA--GLQelggNATLLFYG---S 302

                        250
                 ....*....|....*...
gi 503024272 239 EDQKEGARAFLEKRPPKF 256
Cdd:PLN02921 303 EEGNEGRTAYLEGRAPDF 320
PRK05864 PRK05864
enoyl-CoA hydratase; Provisional
 12-256 1.53e-19

enoyl-CoA hydratase; Provisional


Pssm-ID: 168278 [Multi-domain]  Cd Length: 276  Bit Score: 85.27  E-value: 1.53e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  12 QIAVVTIDHPP-MNALDEATKEAIGRVFDELDQRRDeLRAAILRGAGdKAFVAGADINSFLT------LT-PDAAKRRQK 83
Cdd:PRK05864  19 EIALITLNRPErMNSMAFDVMVPLKEALAEVSYDNS-VRVVVLTGAG-RGFSSGADHKSAGVvphvegLTrPTYALRSME 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  84 RTHAIVAKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNlaifpgNGGTVRSL-------RHAPLGK 156
Cdd:PRK05864  97 LLDDVILALRRLHQPVIAAVNGPAIGGGLCLALAADIRVASSSAYFRAAGIN------NGLTASELglsyllpRAIGSSR 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 157 VKELIFGGEMISAQEALACGLIEKVVPRGQALEAAMTLARRIAGRGPLGVAAAKKSINR---ARELSVAMGLESESDLWS 233
Cdd:PRK05864 171 AFEIMLTGRDVDAEEAERIGLVSRQVPDEQLLDTCYAIAARMAGFSRPGIELTKRTLWSgldAASLEAHMQAEGLGQLFV 250

                        250       260
                 ....*....|....*....|...
gi 503024272 234 GLcATEDQKEGARAFLEKRPPKF 256
Cdd:PRK05864 251 RL-LTANFEEAVAARAEKRPPVF 272
PRK05870 PRK05870
enoyl-CoA hydratase; Provisional
 1-233 5.14e-18

enoyl-CoA hydratase; Provisional


Pssm-ID: 180298  Cd Length: 249  Bit Score: 80.54  E-value: 5.14e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   1 MAELCSYVIEEQIAVVTIDHPP-MNALDEATKEAIGRVFDELDQRRDeLRAAILRGAGdKAFVAGADINSFLTLTPDAAK 79
Cdd:PRK05870   1 MMDPVLLDVDDGVALITVNDPDrRNAVTAEMSAQLRAAVAAAEADPD-VHALVVTGAG-KAFCAGADLTALGAAPGRPAE 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  80 RRQKRTHAIVAKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTVRSLRHAPLGKVKE 159
Cdd:PRK05870  79 DGLRRIYDGFLAVASCPLPTIAAVNGAAVGAGLNLALAADVRIAGPKALFDARFQKLGLHPGGGATWMLQRAVGPQVARA 158

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 503024272 160 LIFGGEMISAQEALACGLIEKVVPRGQAleAAMTLARRIAGRGPLGVAAAKKSINRAR---ELSVAMGLESESDLWS 233
Cdd:PRK05870 159 ALLFGMRFDAEAAVRHGLALMVADDPVA--AALELAAGPAAAPRELVLATKASMRATAslaQHAAAVEFELGPQAAS 233
PRK07327 PRK07327
enoyl-CoA hydratase/isomerase family protein;
16-256 7.01e-18

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 235991  Cd Length: 268  Bit Score: 80.45  E-value: 7.01e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  16 VTIDHP-PMNALDEATKEAIGRVFDELDqRRDELRAAILRGAGdKAFVAGADINSFLTLT--PDAAKRRQKRTHAIVAKI 92
Cdd:PRK07327  25 IVLNGPgALNAADARMHRELADIWRDVD-RDPDVRVVLIRGEG-KAFSAGGDLALVEEMAddFEVRARVWREARDLVYNV 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  93 EDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNggtvrslrHA----PL----GKVKELIFGG 164
Cdd:PRK07327 103 INCDKPIVSAIHGPAVGAGLVAALLADISIAAKDARIIDGHTRLGVAAGD--------HAaivwPLlcgmAKAKYYLLLC 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 165 EMISAQEALACGLIEKVVPRGQALEAAMTLARRIAGRGPLGVAAAKKSINR-------ARELSVA---MGLesesdlwsg 234
Cdd:PRK07327 175 EPVSGEEAERIGLVSLAVDDDELLPKALEVAERLAAGSQTAIRWTKYALNNwlrmagpTFDTSLAlefMGF--------- 245

                        250       260
                 ....*....|....*....|..
gi 503024272 235 lcATEDQKEGARAFLEKRPPKF 256
Cdd:PRK07327 246 --SGPDVREGLASLREKRAPDF 265
PRK07110 PRK07110
polyketide biosynthesis enoyl-CoA hydratase; Validated
 9-226 3.89e-17

polyketide biosynthesis enoyl-CoA hydratase; Validated


Pssm-ID: 235936  Cd Length: 249  Bit Score: 78.09  E-value: 3.89e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   9 IEEQIAVVTIDHPP-MNALDEATKEAIGRVFDELDQRRDeLRAAILRGAgDKAFVAGADINSFLTLTpdaakrrQKRTHA 87
Cdd:PRK07110  11 VEEGIAQVTMQDRVnKNAFSDELCDQLHEAFDTIAQDPR-YKVVILTGY-PNYFATGGTQEGLLSLQ-------TGKGTF 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  88 IVAKIE----DFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGT--VRSLRHAPLGkvKELI 161
Cdd:PRK07110  82 TEANLYslalNCPIPVIAAMQGHAIGGGLVLGLYADIVVLSRESVYTANFMKYGFTPGMGATaiLPEKLGLALG--QEML 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 503024272 162 FGGEMISAQEALACGLIEKVVPRGQALEAAMTLARRIAgRGPLGVAAAKKS---INRARELSVAMGLE 226
Cdd:PRK07110 160 LTARYYRGAELKKRGVPFPVLPRAEVLEKALELARSLA-EKPRHSLVLLKDhlvADRRRRLPEVIEQE 226
PRK07396 PRK07396
dihydroxynaphthoic acid synthetase; Validated
 7-256 4.49e-17

dihydroxynaphthoic acid synthetase; Validated


Pssm-ID: 180958 [Multi-domain]  Cd Length: 273  Bit Score: 78.40  E-value: 4.49e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   7 YVIEEQIAVVTIDHPP-MNALDEAT-KEAIgrvfDELDQRRD--ELRAAILRGAGDKAFVAGADinsfltltpdaakrrQ 82
Cdd:PRK07396  17 YKSADGIAKITINRPEvRNAFRPKTvKEMI----DAFADARDddNIGVIILTGAGDKAFCSGGD---------------Q 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  83 K-RTHA------IVAKIE--DFQW-------PVIAAIDGFCLGGGLELALCCDVRYAEEQSRFG--FPEVnlAIFPGNGG 144
Cdd:PRK07396  78 KvRGYGgyvdddGVPRLNvlDLQRlirtcpkPVIAMVAGYAIGGGHVLHLVCDLTIAADNAIFGqtGPKV--GSFDGGYG 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 145 TVRSLRHAPLGKVKELIFGGEMISAQEALACGLIEKVVPRGQALEAAMTLARRIAGRGPLGVAAAKKSINrarelsvamg 224
Cdd:PRK07396 156 ASYLARIVGQKKAREIWFLCRQYDAQEALDMGLVNTVVPLADLEKETVRWCREMLQNSPMALRCLKAALN---------- 225

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 503024272 225 leSESDLWSGL-----------CATEDQKEGARAFLEKRPPKF 256
Cdd:PRK07396 226 --ADCDGQAGLqelagnatmlfYMTEEAQEGRNAFNEKRQPDF 266
PRK08272 PRK08272
crotonase/enoyl-CoA hydratase family protein;
7-226 9.27e-17

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236213  Cd Length: 302  Bit Score: 77.77  E-value: 9.27e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   7 YVIEEQIAVVTIDHPP-MNALDEATKEAIGRVFDELDQRrDELRAAILRGAGdKAFVAGADINSF------LTLTPDAAK 79
Cdd:PRK08272  14 YEVTGRIARITLNRPEkGNAITADTPLELRAAVERADLD-PGVHVILVSGAG-KGFCAGYDLSAYaegsssGGGGGAYPG 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  80 RRQKRTH---AIVAKIEDFQW----------------PVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFP 140
Cdd:PRK08272  92 KRQAVNHlpdDPWDPMIDYQMmsrfvrgfmslwhahkPTVAKVHGYCVAGGTDIALHCDQVIAADDAKIGYPPTRVWGVP 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 141 GNGGTVRSLRHAplgKVKELIFGGEMISAQEALACGLIEKVVPRGQALEAAMTLARRIAGRGPLGVAAAKKSINRARELs 220
Cdd:PRK08272 172 ATGMWAYRLGPQ---RAKRLLFTGDCITGAQAAEWGLAVEAVPPEELDERTERLVERIAAVPVNQLAMVKLAVNSALLQ- 247


                 ....*.
gi 503024272 221 vaMGLE 226
Cdd:PRK08272 248 --QGVA 251
PRK07468 PRK07468
crotonase/enoyl-CoA hydratase family protein;
13-258 1.36e-16

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180987 [Multi-domain]  Cd Length: 262  Bit Score: 77.02  E-value: 1.36e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  13 IAVVTIDHPPM-NALDEATKEAIGRVFDELDqRRDELRAAILRGAGdKAFVAGADINSFLT-LTPDAAKRRQ--KRTHAI 88
Cdd:PRK07468  15 VATLTLNRPEKhNALSARMIAELTTAARRLA-ADAAVRVVVLTGAG-KSFCAGGDLGWMRAqMTADRATRIEeaRRLAMM 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  89 VAKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTVRSLRHAPlGKVKELIFGGEMIS 168
Cdd:PRK07468  93 LKALNDLPKPLIGRIQGQAFGGGVGLISVCDVAIAVSGARFGLTETRLGLIPATISPYVVARMGE-ANARRVFMSARLFD 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 169 AQEALACGLIEKVVPRGQ---ALEAAMTLARRIAgrgPLGVAAAKKSINR----ARELSVAMGLESESDLWSglcaTEDQ 241
Cdd:PRK07468 172 AEEAVRLGLLSRVVPAERldaAVEAEVTPYLSCA---PGAVAAAKALVRAlgapIDEAVIDATIEALADTWE----TEEA 244

                        250
                 ....*....|....*..
gi 503024272 242 KEGARAFLEKRPPKFLG 258
Cdd:PRK07468 245 REGIAAFFDKRAPAWRG 261
PLN03214 PLN03214
probable enoyl-CoA hydratase/isomerase; Provisional
 13-216 5.78e-15

probable enoyl-CoA hydratase/isomerase; Provisional


Pssm-ID: 215635  Cd Length: 278  Bit Score: 72.61  E-value: 5.78e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  13 IAVVTIDHPPMNALDEATKEAIGRVFDELdQRRDELRAAILRGAGDK-AFVAGADINSFLTLTPDAAKRRQ--KRTHAIV 89
Cdd:PLN03214  22 IAVVWLAKEPVNSMTLAMWRSLDDALTAL-ENDPTVRGVVFASGLRRdVFTAGNDIAELYAPKTSAARYAEfwLTQTTFL 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  90 AKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAI----FPGNGGTVRSLRHAplgKVKELIFGGE 165
Cdd:PLN03214 101 VRLLRSRLATVCAIRGACPAGGCAVSLCCDYRLQTTEGTMGLNEVALGIpvpkFWARLFMGRVIDRK---VAESLLLRGR 177

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 503024272 166 MISAQEALACGLIEKVVPRGQALEAAMTLARRIAGRGPLGVAAAKKSINRA 216
Cdd:PLN03214 178 LVRPAEAKQLGLIDEVVPAAALMEAAASAMERALKLPSAARAATKALLREE 228
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 13-191 1.07e-14

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 72.50  E-value: 1.07e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   13 IAVVTIDHPP-MNALDEATKEAIGRVFDELDQRrDELRAAILRGAGDKAFVAGADI----NSFLTLTPDAAKRRQKRTHA 87
Cdd:pfam16113   1 VGVITLNRPKaLNALNLEMVRALLAALKAWEDD-PAVKLVVLKGAGERAFCAGGDVralyEAAKAGGGEAGRDFFREEYR 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   88 IVAKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTvRSLRHAP--LGkvkeLIFG-- 163
Cdd:pfam16113  80 LNYLIATYPKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPDVGGS-YFLSRLPgeLG----LYLAlt 154

                         170       180       190
                  ....*....|....*....|....*....|
gi 503024272  164 GEMISAQEALACGLIEKVVPRG--QALEAA 191
Cdd:pfam16113 155 GARLNGADALAAGLATHYVPSArlPALEEA 184
PRK07827 PRK07827
enoyl-CoA hydratase family protein;
1-254 2.44e-14

enoyl-CoA hydratase family protein;


Pssm-ID: 236109 [Multi-domain]  Cd Length: 260  Bit Score: 70.48  E-value: 2.44e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   1 MAELCSYVIEEQIAVVTIDHPP-MNALDEATkeaIGRVFDELDQRRDE--LRAAILRGAGdKAFVAGADINSFLTLTPDA 77
Cdd:PRK07827   4 VDTLVRYAVDGGVATLTLDSPHnRNALSARL---VAQLHDGLRAAAADpaVRAVVLTHTG-GTFCAGADLSEAGGGGGDP 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  78 AKRRQKRTHAIVA---KIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPgnggTVRSLR---H 151
Cdd:PRK07827  80 YDAAVARAREMTAllrAIVELPKPVIAAIDGHVRAGGFGLVGACDIVVAGPESTFALTEARIGVAP----AIISLTllpR 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 152 APLGKVKELIFGGEMISAQEALACGLIEKVVPRGQALEAAMTLARRIAgrGPLGVAAAKKSINRARELSVAMGLESESDL 231
Cdd:PRK07827 156 LSPRAAARYYLTGEKFGAAEAARIGLVTAAADDVDAAVAALLADLRRG--SPQGLAESKALTTAAVLAGFDRDAEELTEE 233

                        250       260
                 ....*....|....*....|...
gi 503024272 232 WSGLCATEDQKEGARAFLEKRPP 254
Cdd:PRK07827 234 SARLFVSDEAREGMTAFLQKRPP 256
PRK08321 PRK08321
1,4-dihydroxy-2-naphthoyl-CoA synthase;
98-256 2.26e-13

1,4-dihydroxy-2-naphthoyl-CoA synthase;


Pssm-ID: 181386  Cd Length: 302  Bit Score: 68.51  E-value: 2.26e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  98 PVIAAIDGFCLGGGLELALCCDVRYA-EEQSRFGFPEVNLAIFPGNGGTVRSLRHAPLGKVKELIFGGEMISAQEALACG 176
Cdd:PRK08321 137 VVIAVVPGWAAGGGHSLHVVCDLTLAsREHARFKQTDADVGSFDGGYGSAYLARQVGQKFAREIFFLGRTYSAEEAHDMG 216

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 177 LIEKVVPRGQALEAAMTLARRIAGRGPLGVAAAKKSINRARElsvamGLESESdLWSGLC-----ATEDQKEGARAFLEK 251
Cdd:PRK08321 217 AVNAVVPHAELETEALEWAREINGKSPTAMRMLKYAFNLTDD-----GLVGQQ-LFAGEAtrlayMTDEAQEGRDAFLEK 290


                 ....*
gi 503024272 252 RPPKF 256
Cdd:PRK08321 291 RDPDW 295
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
 12-213 1.08e-12

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 66.77  E-value: 1.08e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  12 QIAVVTIDHP-PMNALDEATKEAIGRVFDELdQRRDELRAAILRGAGDKAFVAGADINSFLtltpDAAKRRQKRTH---- 86
Cdd:PRK05617  12 GVGVITLNRPkALNALSLEMIRAIDAALDAW-EDDDAVAAVVIEGAGERGFCAGGDIRALY----EAARAGDPLAAdrff 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  87 ----AIVAKIEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTVRsLRHAPlGKVKE-LI 161
Cdd:PRK05617  87 reeyRLNALIARYPKPYIALMDGIVMGGGVGISAHGSHRIVTERTKMAMPETGIGFFPDVGGTYF-LSRAP-GALGTyLA 164

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 503024272 162 FGGEMISAQEALACGLIEKVVPRGQALEAAMTLARRIAGRGPLGVAAAKKSI 213
Cdd:PRK05617 165 LTGARISAADALYAGLADHFVPSADLPALLDALISLRWDSGADVVDAALAAF 216
PRK07260 PRK07260
enoyl-CoA hydratase; Provisional
 7-252 1.38e-12

enoyl-CoA hydratase; Provisional


Pssm-ID: 180910 [Multi-domain]  Cd Length: 255  Bit Score: 65.53  E-value: 1.38e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   7 YVIEEQIAVVTIDHPPM-NALDEATKEAIGRVFDELdqRRDELRAAILRGAGDKAFVAGADINSFLTLTPDAAKRRQKRT 85
Cdd:PRK07260   6 YEVEDDLATLTLNRPEVsNGFNIPMCQEILEALRLA--EEDPSVRFLLINANGKVFSVGGDLVEMKRAVDEDDVQSLVKI 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  86 HAIVAKI----EDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTVRSLRHAPLGKVKELI 161
Cdd:PRK07260  84 AELVNEIsfaiKQLPKPVIMCVDGAVAGAAANMAVAADFCIASTKTKFIQAFVGVGLAPDAGGLFLLTRAIGLNRATHLA 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 162 FGGEMISAQEALACGLIEKVVPRGQALEAAMTLARRIAgRGPLGVAAAKKSINRARELSvamGLES----ESDLWSGLCA 237
Cdd:PRK07260 164 MTGEALTAEKALEYGFVYRVAESEKLEKTCEQLLKKLR-RGSSNSYAAIKSLVWESFFK---GWEDyaklELALQESLAF 239

                        250
                 ....*....|....*
gi 503024272 238 TEDQKEGARAFLEKR 252
Cdd:PRK07260 240 KEDFKEGVRAFSERR 254
PRK12478 PRK12478
crotonase/enoyl-CoA hydratase family protein;
7-256 4.44e-12

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 183548  Cd Length: 298  Bit Score: 64.59  E-value: 4.44e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   7 YVIEEQIAVVTIDHP--------PMNALDEAtkeAIGrvfdeLDQRRDELRAAILRGAGdKAFVAGADINSFL-----TL 73
Cdd:PRK12478   9 YTTAGPVATITLNRPeqlntivpPMPDEIEA---AIG-----LAERDQDIKVIVLRGAG-RAFSGGYDFGGGFqhwgeAM 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  74 TPDAAKRRQKRTHAIVAK----IEDFQ--W----PVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAifpGNG 143
Cdd:PRK12478  80 MTDGRWDPGKDFAMVTARetgpTQKFMaiWraskPVIAQVHGWCVGGASDYALCADIVIASDDAVIGTPYSRMW---GAY 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 144 GTVRSLRHAPLGKVKELIFGGEMISAQEALACGLIEKVVPRGQaLEAAM-TLARRIAgRGPLGVAAAKKSI-NRARElsv 221
Cdd:PRK12478 157 LTGMWLYRLSLAKVKWHSLTGRPLTGVQAAEAELINEAVPFER-LEARVaEVATELA-RIPLSQLQAQKLIvNQAYE--- 231

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 503024272 222 AMGLESESDL---WSGLCA-TED--------QKEGARAFLEKRPPKF 256
Cdd:PRK12478 232 NMGLASTQTLggiLDGLMRnTPDalefirtaETQGVRAAVERRDGPF 278
PRK06023 PRK06023
crotonase/enoyl-CoA hydratase family protein;
46-251 1.03e-11

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 168351  Cd Length: 251  Bit Score: 63.27  E-value: 1.03e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  46 DELRAAILRGAgDKAFVAGADINSFLTLTPDAAKRRQKRTHAIVAKIEdFQWPVIAAIDGFCLGGGLELALCCDVRYAEE 125
Cdd:PRK06023  49 DAIRAHVFLGT-EGCFSAGNDMQDFLAAAMGGTSFGSEILDFLIALAE-AEKPIVSGVDGLAIGIGTTIHLHCDLTFASP 126

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 126 QSRFGFPEVNLAIFPGNGGTVRSLRHAPLGKVKELIFGGEMISAQEALACGLIEKVVPRGQALEAAMTLARRIAGRGPLG 205
Cdd:PRK06023 127 RSLFRTPFVDLALVPEAGSSLLAPRLMGHQRAFALLALGEGFSAEAAQEAGLIWKIVDEEAVEAETLKAAEELAAKPPQA 206

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 503024272 206 VAAAKKSINRARELSVAMgLESESDLWSGLCATEDQKEGARAFLEK 251
Cdd:PRK06023 207 LQIARDLMRGPREDILAR-IDEEAKHFAARLKSAEARAAFEAFMRR 251
PRK06213 PRK06213
crotonase/enoyl-CoA hydratase family protein;
1-217 1.53e-11

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235744  Cd Length: 229  Bit Score: 62.30  E-value: 1.53e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   1 MAELCSYVIEEQIAVVTIDHPPMNALDEATKEAIGRVFDELDQRRdelrAAILRGAGDKAFVAGADINSFlTLTPDAAKR 80
Cdd:PRK06213   1 MSELVSYTLEDGVATITLDDGKVNALSPAMIDALNAALDQAEDDR----AVVVITGQPGIFSGGFDLKVM-TSGAQAAIA 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  81 RQKRTHAIVAKIEDFQWPVIAAIDGFCLGGGLELALCCDVRY-AEEQSRFGFPEVNLAI-FPGNGGTVRSLRHAPLGKVK 158
Cdd:PRK06213  76 LLTAGSTLARRLLSHPKPVIVACTGHAIAKGAFLLLSADYRIgVHGPFKIGLNEVAIGMtMPHAAIELARDRLTPSAFQR 155

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 503024272 159 ELIFGgEMISAQEALACGLIEKVVPRGQALEAAMTLARRIAGrgpLGVAAAKKSINRAR 217
Cdd:PRK06213 156 AVINA-EMFDPEEAVAAGFLDEVVPPEQLLARAQAAARELAG---LNMGAHAATKLKVR 210
PLN02157 PLN02157
3-hydroxyisobutyryl-CoA hydrolase-like protein
 21-177 3.85e-09

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 177817 [Multi-domain]  Cd Length: 401  Bit Score: 56.62  E-value: 3.85e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  21 PPMNALDEATKEAIGRVFDELDQRRDeLRAAILRGAGdKAFVAGADINSFLTL----TPDAAKRRQKRTHAIVAKIEDFQ 96
Cdd:PLN02157  56 PALNALTTHMGYRLQKLYKNWEEDPN-IGFVMMKGSG-RAFCAGGDIVSLYHLrkrgSPDAIREFFSSLYSFIYLLGTYL 133

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  97 WPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTVrSLRHAPlGKVKELI-FGGEMISAQEALAC 175
Cdd:PLN02157 134 KPHVAILNGVTMGGGTGVSIPGTFRVATDRTIFATPETIIGFHPDAGASF-NLSHLP-GRLGEYLgLTGLKLSGAEMLAC 211


                 ..
gi 503024272 176 GL 177
Cdd:PLN02157 212 GL 213
PLN02851 PLN02851
3-hydroxyisobutyryl-CoA hydrolase-like protein
 23-177 8.06e-08

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178443 [Multi-domain]  Cd Length: 407  Bit Score: 52.29  E-value: 8.06e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  23 MNALDEATKEAIGRVFDELDQRRDeLRAAILRGAGdKAFVAGADINSFLTLTPDAAKRRQKRTHAIVAKIEDFQW----P 98
Cdd:PLN02851  63 LNALTIPMVARLKRLYESWEENPD-IGFVLMKGSG-RAFCSGADVVSLYHLINEGNVEECKLFFENLYKFVYLQGtylkP 140

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  99 VIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPgNGGTVRSLRHAPlGKVKE-LIFGGEMISAQEALACGL 177
Cdd:PLN02851 141 NVAIMDGITMGCGAGISIPGMFRVVTDKTVFAHPEVQMGFHP-DAGASYYLSRLP-GYLGEyLALTGQKLNGVEMIACGL 218
PRK05674 PRK05674
gamma-carboxygeranoyl-CoA hydratase; Validated
 32-254 1.56e-07

gamma-carboxygeranoyl-CoA hydratase; Validated


Pssm-ID: 168168  Cd Length: 265  Bit Score: 50.96  E-value: 1.56e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  32 EAIGRVFDELDQRRD--ELRAAILRGAGdKAFVAGADIN--------SFLTLTPDAAKRRQKRTHAIVAKIedfqwPVIA 101
Cdd:PRK05674  33 QMIRELILALDQVQSdaSLRFLLLRGRG-RHFSAGADLAwmqqsadlDYNTNLDDARELAELMYNLYRLKI-----PTLA 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272 102 AIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPgngGTVRSLRHAPLGK--VKELIFGGEMISAQEALACGLIE 179
Cdd:PRK05674 107 VVQGAAFGGALGLISCCDMAIGADDAQFCLSEVRIGLAP---AVISPFVVKAIGEraARRYALTAERFDGRRARELGLLA 183

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 503024272 180 KVVPRGQALEAAMTLARRIAGRGPLGVAAAKKSINR--ARELSVAMGLESESDLWSGLCATEDQkEGARAFLEKRPP 254
Cdd:PRK05674 184 ESYPAAELEAQVEAWIANLLLNSPQALRASKDLLREvgDGELSPALRRYCENAIARIRVSAEGQ-EGLRAFLEKRTP 259
PLN02988 PLN02988
3-hydroxyisobutyryl-CoA hydrolase
 1-192 3.07e-06

3-hydroxyisobutyryl-CoA hydrolase


Pssm-ID: 178568 [Multi-domain]  Cd Length: 381  Bit Score: 47.79  E-value: 3.07e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272   1 MAELCSYVIEEQ--IAVVTIDHPP-MNALDEATKEAIGRVFDELDQRrDELRAAILRGAGdKAFVAGADINSFLTLTPDA 77
Cdd:PLN02988   5 MASQSQVLVEEKssVRILTLNRPKqLNALSFHMISRLLQLFLAFEED-PSVKLVILKGHG-RAFCAGGDVAAVVRDIEQG 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  78 AKR-------RQKRTHAIVAKIEDFQwpvIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAIFPGNGGTVrSLR 150
Cdd:PLN02988  83 NWRlganffsDEYMLNYVMATYSKAQ---VSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASY-FLS 158

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 503024272 151 HAPlGKVKELI-FGGEMISAQEALACGLIEKVVP--RGQALEAAM 192
Cdd:PLN02988 159 RLP-GFFGEYVgLTGARLDGAEMLACGLATHFVPstRLTALEADL 202
PLN02267 PLN02267
enoyl-CoA hydratase/isomerase family protein
 88-230 5.24e-06

enoyl-CoA hydratase/isomerase family protein


Pssm-ID: 215151  Cd Length: 239  Bit Score: 46.25  E-value: 5.24e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  88 IVAKIEDFQWPVIAAIDGFCLGGGLELALCCD---------VRYAEEQS-RFGFPEVNLAIFPGNGGTVRSLRhaplgkv 157
Cdd:PLN02267  86 LVADLISLPMPTIAAVTGHASAAGFILALSHDyvlmrkdrgVLYMSEVDiGLPLPDYFMALLRAKIGSPAARR------- 158

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 503024272 158 kELIFGGEMISAQEALACGLIEKVVPRGQAL-EAAMTLARRIAGRGPLGVAAAKKSINRARELSVAMGLESESD 230
Cdd:PLN02267 159 -DVLLRAAKLTAEEAVEMGIVDSAHDSAEETvEAAVRLGEELAARKWNGEVYASIRKSLLPEVCGKLGLDEEVE 231
PLN02874 PLN02874
3-hydroxyisobutyryl-CoA hydrolase-like protein
 15-194 6.26e-05

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178462 [Multi-domain]  Cd Length: 379  Bit Score: 43.63  E-value: 6.26e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  15 VVTIDHP-PMNALDEATKEAIGRVFDELdQRRDELRAAILRGAGdKAFVAGADINSF--LTLTPDAAKRRQKRTHAIVAK 91
Cdd:PLN02874  23 VITLNRPrQLNVISLSVVSLLAEFLEQW-EKDDSVELIIIKGAG-RAFSAGGDLKMFydGRESDDSCLEVVYRMYWLCYH 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503024272  92 IEDFQWPVIAAIDGFCLGGGLELALCCDVRYAEEQSRFGFPEVNLAiFPGNGGTVRSLRHAPlGKVKE-LIFGGEMISAQ 170
Cdd:PLN02874 101 IHTYKKTQVALVHGLVMGGGAGLMVPMKFRVVTEKTVFATPEASVG-FHTDCGFSYILSRLP-GHLGEyLALTGARLNGK 178

                        170       180
                 ....*....|....*....|....
gi 503024272 171 EALACGLIEKVVPRGQALEAAMTL 194
Cdd:PLN02874 179 EMVACGLATHFVPSEKLPELEKRL 202
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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