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Conserved domains on  [gi|499747296|ref|WP_011428030|]
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alpha/beta fold hydrolase [Rhizobium etli]

Protein Classification

alpha/beta fold hydrolase( domain architecture ID 11426811)

alpha/beta hydrolase family protein catalyzes the hydrolysis of substrates with different chemical composition or physicochemical properties using a nucleophile-His-acid catalytic triad

PubMed:  1409539|12369917

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 41-319 3.70e-49

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


:

Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 163.63  E-value: 3.70e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296  41 RTAKIDGLDIFYREAGPaDAPVVLLLHGFPTSSHMFRNLIPLLADRYHVIAPDYPGYGQSAAPDRGtyaYTFAGAADIVD 120
Cdd:COG0596    5 RFVTVDGVRLHYREAGP-DGPPVVLLHGLPGSSYEWRPLIPALAAGYRVIAPDLRGHGRSDKPAGG---YTLDDLADDLA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296 121 KLMVHLEAKSYAMYVMDYGAPVGYRLALKHPERVSGLIIQNgnayeEGLKEFWDPIKTywsdgSDKSRAALSGLVTLett 200
Cdd:COG0596   81 ALLDALGLERVVLVGHSMGGMVALELAARHPERVAGLVLVD-----EVLAALAEPLRR-----PGLAPEALAALLRA--- 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296 201 kFQYTDGMEDVSRIspdnwvhdqalldrpgnkdiqldmlydyrtnvplypdfqrffrerKPPTLIVWGKNDYIFPEAGAH 280
Cdd:COG0596  148 -LARTDLRERLARI---------------------------------------------TVPTLVIWGEKDPIVPPALAR 181

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 499747296 281 PYLKDLPDAEIHIL-NSGHFLLEEKLDVAAPLINDFLDRN 319
Cdd:COG0596  182 RLAELLPNAELVVLpGAGHFPPLEQPEAFAAALRDFLARL 221
 
Name Accession Description Interval E-value
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 41-319 3.70e-49

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 163.63  E-value: 3.70e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296  41 RTAKIDGLDIFYREAGPaDAPVVLLLHGFPTSSHMFRNLIPLLADRYHVIAPDYPGYGQSAAPDRGtyaYTFAGAADIVD 120
Cdd:COG0596    5 RFVTVDGVRLHYREAGP-DGPPVVLLHGLPGSSYEWRPLIPALAAGYRVIAPDLRGHGRSDKPAGG---YTLDDLADDLA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296 121 KLMVHLEAKSYAMYVMDYGAPVGYRLALKHPERVSGLIIQNgnayeEGLKEFWDPIKTywsdgSDKSRAALSGLVTLett 200
Cdd:COG0596   81 ALLDALGLERVVLVGHSMGGMVALELAARHPERVAGLVLVD-----EVLAALAEPLRR-----PGLAPEALAALLRA--- 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296 201 kFQYTDGMEDVSRIspdnwvhdqalldrpgnkdiqldmlydyrtnvplypdfqrffrerKPPTLIVWGKNDYIFPEAGAH 280
Cdd:COG0596  148 -LARTDLRERLARI---------------------------------------------TVPTLVIWGEKDPIVPPALAR 181

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 499747296 281 PYLKDLPDAEIHIL-NSGHFLLEEKLDVAAPLINDFLDRN 319
Cdd:COG0596  182 RLAELLPNAELVVLpGAGHFPPLEQPEAFAAALRDFLARL 221
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 61-304 3.10e-31

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 117.61  E-value: 3.10e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296   61 PVVLLLHGFPTSSHMFRNLIPLLA-DRYHVIAPDYPGYGQSAAPdRGTYAYTFAGAADIVDKLMVHLEAKSYAMYVMDYG 139
Cdd:pfam00561   1 PPVLLLHGLPGSSDLWRKLAPALArDGFRVIALDLRGFGKSSRP-KAQDDYRTDDLAEDLEYILEALGLEKVNLVGHSMG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296  140 APVGYRLALKHPERVSGLIIQNGNAYEEGLKEFWDPIKTYWSDGSDK--SRAALSGLVTLETTKFQYTDGMEDVSRISPD 217
Cdd:pfam00561  80 GLIALAYAAKYPDRVKALVLLGALDPPHELDEADRFILALFPGFFDGfvADFAPNPLGRLVAKLLALLLLRLRLLKALPL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296  218 -NWVHDQALLDRPGNKDIQLDMLYDYRTNVPLYPDFQRFfrerKPPTLIVWGKNDYIFPEAGAHPYLKDLPDA-EIHILN 295
Cdd:pfam00561 160 lNKRFPSGDYALAKSLVTGALLFIETWSTELRAKFLGRL----DEPTLIIWGDQDPLVPPQALEKLAQLFPNArLVVIPD 235


                  ....*....
gi 499747296  296 SGHFLLEEK 304
Cdd:pfam00561 236 AGHFAFLEG 244
PRK03592 PRK03592
haloalkane dehalogenase; Provisional
 34-157 5.71e-24

haloalkane dehalogenase; Provisional


Pssm-ID: 235135  Cd Length: 295  Bit Score: 99.30  E-value: 5.71e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296  34 APAPVHYRTAKIDGLDIFYREAGpaDAPVVLLLHGFPTSSHMFRNLIPLLADRYHVIAPDYPGYGQSAAPDRGtyaYTFA 113
Cdd:PRK03592   3 VEPPGEMRRVEVLGSRMAYIETG--EGDPIVFLHGNPTSSYLWRNIIPHLAGLGRCLAPDLIGMGASDKPDID---YTFA 77

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 499747296 114 GAADIVDKLMVHLEAKSYAMYVMDYGAPVGYRLALKHPERVSGL 157
Cdd:PRK03592  78 DHARYLDAWFDALGLDDVVLVGHDWGSALGFDWAARHPDRVRGI 121
bioH TIGR01738
pimelyl-[acyl-carrier protein] methyl ester esterase; This CoA-binding enzyme is required for ...
 61-298 9.76e-08

pimelyl-[acyl-carrier protein] methyl ester esterase; This CoA-binding enzyme is required for the production of pimeloyl-coenzyme A, the substrate of the BioF protein early in the biosynthesis of biotin. Its exact function is unknown, but is proposed in ref 2. This enzyme belongs to the alpha/beta hydrolase fold family (pfam00561). Members of this family are restricted to the Proteobacteria. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin]


Pssm-ID: 273783 [Multi-domain]  Cd Length: 245  Bit Score: 52.13  E-value: 9.76e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296   61 PVVLLLHGFPTSSHMFRNLIPLLADRYHVIAPDYPGYGQSAapdrgtyAYTFAGAADIVDKLMVHLEAKsyAMYV-MDYG 139
Cdd:TIGR01738   5 VHLVLIHGWGMNAEVFRCLDEELSAHFTLHLVDLPGHGRSR-------GFGPLSLADMAEAIAAQAPDP--AIWLgWSLG 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296  140 APVGYRLALKHPERVSGLIIQNGNA-------YEEGLKEfwDPIKTYWSDGSDKSRAALSGLVTLETTKFQYTDGmeDVS 212
Cdd:TIGR01738  76 GLVALHIAATHPDRVRALVTVASSPcfsaredWPEGIKP--DVLTGFQQQLSDDYQRTIERFLALQTLGTPTARQ--DAR 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296  213 RISPDnwvhdqaLLDR--PGNKDIQ--LDMLYDYrtnvplypDFQRFFRERKPPTLIVWGKNDYIFPEAGAHPYLKDLPD 288
Cdd:TIGR01738 152 ALKQT-------LLARptPNVQVLQagLEILATV--------DLRQPLQNISVPFLRLYGYLDGLVPAKVVPMLDKLAPH 216

                         250
                  ....*....|.
gi 499747296  289 AEIHILN-SGH 298
Cdd:TIGR01738 217 SELYIFAkAAH 227
 
Name Accession Description Interval E-value
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 41-319 3.70e-49

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 163.63  E-value: 3.70e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296  41 RTAKIDGLDIFYREAGPaDAPVVLLLHGFPTSSHMFRNLIPLLADRYHVIAPDYPGYGQSAAPDRGtyaYTFAGAADIVD 120
Cdd:COG0596    5 RFVTVDGVRLHYREAGP-DGPPVVLLHGLPGSSYEWRPLIPALAAGYRVIAPDLRGHGRSDKPAGG---YTLDDLADDLA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296 121 KLMVHLEAKSYAMYVMDYGAPVGYRLALKHPERVSGLIIQNgnayeEGLKEFWDPIKTywsdgSDKSRAALSGLVTLett 200
Cdd:COG0596   81 ALLDALGLERVVLVGHSMGGMVALELAARHPERVAGLVLVD-----EVLAALAEPLRR-----PGLAPEALAALLRA--- 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296 201 kFQYTDGMEDVSRIspdnwvhdqalldrpgnkdiqldmlydyrtnvplypdfqrffrerKPPTLIVWGKNDYIFPEAGAH 280
Cdd:COG0596  148 -LARTDLRERLARI---------------------------------------------TVPTLVIWGEKDPIVPPALAR 181

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 499747296 281 PYLKDLPDAEIHIL-NSGHFLLEEKLDVAAPLINDFLDRN 319
Cdd:COG0596  182 RLAELLPNAELVVLpGAGHFPPLEQPEAFAAALRDFLARL 221
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 61-304 3.10e-31

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 117.61  E-value: 3.10e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296   61 PVVLLLHGFPTSSHMFRNLIPLLA-DRYHVIAPDYPGYGQSAAPdRGTYAYTFAGAADIVDKLMVHLEAKSYAMYVMDYG 139
Cdd:pfam00561   1 PPVLLLHGLPGSSDLWRKLAPALArDGFRVIALDLRGFGKSSRP-KAQDDYRTDDLAEDLEYILEALGLEKVNLVGHSMG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296  140 APVGYRLALKHPERVSGLIIQNGNAYEEGLKEFWDPIKTYWSDGSDK--SRAALSGLVTLETTKFQYTDGMEDVSRISPD 217
Cdd:pfam00561  80 GLIALAYAAKYPDRVKALVLLGALDPPHELDEADRFILALFPGFFDGfvADFAPNPLGRLVAKLLALLLLRLRLLKALPL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296  218 -NWVHDQALLDRPGNKDIQLDMLYDYRTNVPLYPDFQRFfrerKPPTLIVWGKNDYIFPEAGAHPYLKDLPDA-EIHILN 295
Cdd:pfam00561 160 lNKRFPSGDYALAKSLVTGALLFIETWSTELRAKFLGRL----DEPTLIIWGDQDPLVPPQALEKLAQLFPNArLVVIPD 235


                  ....*....
gi 499747296  296 SGHFLLEEK 304
Cdd:pfam00561 236 AGHFAFLEG 244
PRK03592 PRK03592
haloalkane dehalogenase; Provisional
 34-157 5.71e-24

haloalkane dehalogenase; Provisional


Pssm-ID: 235135  Cd Length: 295  Bit Score: 99.30  E-value: 5.71e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296  34 APAPVHYRTAKIDGLDIFYREAGpaDAPVVLLLHGFPTSSHMFRNLIPLLADRYHVIAPDYPGYGQSAAPDRGtyaYTFA 113
Cdd:PRK03592   3 VEPPGEMRRVEVLGSRMAYIETG--EGDPIVFLHGNPTSSYLWRNIIPHLAGLGRCLAPDLIGMGASDKPDID---YTFA 77

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 499747296 114 GAADIVDKLMVHLEAKSYAMYVMDYGAPVGYRLALKHPERVSGL 157
Cdd:PRK03592  78 DHARYLDAWFDALGLDDVVLVGHDWGSALGFDWAARHPDRVRGI 121
PRK00870 PRK00870
haloalkane dehalogenase; Provisional
 48-162 1.68e-22

haloalkane dehalogenase; Provisional


Pssm-ID: 179147 [Multi-domain]  Cd Length: 302  Bit Score: 95.42  E-value: 1.68e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296  48 LDIFYREAGPADAPVVLLLHGFPTSSHMFRNLIPLLADRYH-VIAPDYPGYGQSAAPDRGTyAYTFAGAADIVDKLMVHL 126
Cdd:PRK00870  34 LRMHYVDEGPADGPPVLLLHGEPSWSYLYRKMIPILAAAGHrVIAPDLIGFGRSDKPTRRE-DYTYARHVEWMRSWFEQL 112

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 499747296 127 EAKSYAMYVMDYGAPVGYRLALKHPERVSGLIIQNG 162
Cdd:PRK00870 113 DLTDVTLVCQDWGGLIGLRLAAEHPDRFARLVVANT 148
PRK14875 PRK14875
acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional
 21-316 5.96e-20

acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional


Pssm-ID: 184875 [Multi-domain]  Cd Length: 371  Bit Score: 89.23  E-value: 5.96e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296  21 ASAVPAHATADRQAPAPvhyRTAKIDGLDIFYREAGPADAPVVLLLHGFPTSSHMFRNLIPLLADRYHVIAPDYPGYGQS 100
Cdd:PRK14875  95 RRFAPEGIDEEDAGPAP---RKARIGGRTVRYLRLGEGDGTPVVLIHGFGGDLNNWLFNHAALAAGRPVIALDLPGHGAS 171

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296 101 A-APDRGtyayTFAGAADIVDKLM-------VHLEAKSyamyvmdYGAPVGYRLALKHPERVS--GLIiqnGNAyeeGLk 170
Cdd:PRK14875 172 SkAVGAG----SLDELAAAVLAFLdalgierAHLVGHS-------MGGAVALRLAARAPQRVAslTLI---APA---GL- 233

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296 171 efwdpiktywsdGSDKSRAALSGLVTLETTKfQYTDGMEDVsrispdnwVHDQALLDRPGNKDI----QLDMLYDYRTNV 246
Cdd:PRK14875 234 ------------GPEINGDYIDGFVAAESRR-ELKPVLELL--------FADPALVTRQMVEDLlkykRLDGVDDALRAL 292

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296 247 P--LYPD-FQRF-FRER----KPPTLIVWGKNDYIFPEAGAHpylkDLPD-AEIHILN-SGHFL-LEEKLDVAApLINDF 315
Cdd:PRK14875 293 AdaLFAGgRQRVdLRDRlaslAIPVLVIWGEQDRIIPAAHAQ----GLPDgVAVHVLPgAGHMPqMEAAADVNR-LLAEF 367


                 .
gi 499747296 316 L 316
Cdd:PRK14875 368 L 368
PRK03204 PRK03204
haloalkane dehalogenase; Provisional
 59-315 6.40e-18

haloalkane dehalogenase; Provisional


Pssm-ID: 179554 [Multi-domain]  Cd Length: 286  Bit Score: 82.21  E-value: 6.40e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296  59 DAPVVLLLHGFPTSSHMFRNLIPLLADRYHVIAPDYPGYGQSAAPDrgTYAYTFAGAADIVDKLMVHLEAKSYAMYVMDY 138
Cdd:PRK03204  33 TGPPILLCHGNPTWSFLYRDIIVALRDRFRCVAPDYLGFGLSERPS--GFGYQIDEHARVIGEFVDHLGLDRYLSMGQDW 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296 139 GAPVGYRLALKHPERVSGLIIqnGNAYeeglkeFWdPIktywsDGSDKSraALSGLVTLETTKFQYTDGMEDVSRISPDN 218
Cdd:PRK03204 111 GGPISMAVAVERADRVRGVVL--GNTW------FW-PA-----DTLAMK--AFSRVMSSPPVQYAILRRNFFVERLIPAG 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296 219 ---------WVHDQALLDRPGNKDIQLDMLYDYRTNVPLYPDFQRFFRER--KPPTLIVWGKNDYIF-PEAGAHPYLKDL 286
Cdd:PRK03204 175 tehrpssavMAHYRAVQPNAAARRGVAEMPKQILAARPLLARLAREVPATlgTKPTLLVWGMKDVAFrPKTILPRLRATF 254

                        250       260       270
                 ....*....|....*....|....*....|.
gi 499747296 287 PDAE-IHILNSGHFLLEEKLD-VAAPLINDF 315
Cdd:PRK03204 255 PDHVlVELPNAKHFIQEDAPDrIAAAIIERF 285
PLN03084 PLN03084
alpha/beta hydrolase fold protein; Provisional
 51-161 2.98e-17

alpha/beta hydrolase fold protein; Provisional


Pssm-ID: 178633  Cd Length: 383  Bit Score: 81.47  E-value: 2.98e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296  51 FYREAGPADAPVVLLLHGFPTSSHMFRNLIPLLADRYHVIAPDYPGYGQSAAPDRGT-YAYTFAGAADIVDKLMVHLEAK 129
Cdd:PLN03084 118 FCVESGSNNNPPVLLIHGFPSQAYSYRKVLPVLSKNYHAIAFDWLGFGFSDKPQPGYgFNYTLDEYVSSLESLIDELKSD 197

                         90       100       110
                 ....*....|....*....|....*....|..
gi 499747296 130 SYAMYVMDYGAPVGYRLALKHPERVSGLIIQN 161
Cdd:PLN03084 198 KVSLVVQGYFSPPVVKYASAHPDKIKKLILLN 229
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
46-318 2.58e-15

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 73.50  E-value: 2.58e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296  46 DGLDIFYREAGPADAP--VVLLLHGFPTSSHMFRNLIPLLADR-YHVIAPDYPGYGQSAAPdRGtYAYTFAGAADIVDKL 122
Cdd:COG2267   12 DGLRLRGRRWRPAGSPrgTVVLVHGLGEHSGRYAELAEALAAAgYAVLAFDLRGHGRSDGP-RG-HVDSFDDYVDDLRAA 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296 123 MVHLEAKSYA-MYVM--DYGAPVGYRLALKHPERVSGLIIQNGnayeeglKEFWDPIktywsdgsdksraalsglvtlet 199
Cdd:COG2267   90 LDALRARPGLpVVLLghSMGGLIALLYAARYPDRVAGLVLLAP-------AYRADPL----------------------- 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296 200 tkfqytdgmedvsRISPDNWVHDQALLDRPGNKDIqldmlydyrtnvplypdfqrffrerkpPTLIVWGKNDYIFPEAGA 279
Cdd:COG2267  140 -------------LGPSARWLRALRLAEALARIDV---------------------------PVLVLHGGADRVVPPEAA 179

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 499747296 280 HPYLKDL-PDAEIHIL-NSGHFLLEEKL-DVAAPLINDFLDR 318
Cdd:COG2267  180 RRLAARLsPDVELVLLpGARHELLNEPArEEVLAAILAWLER 221
PRK05855 PRK05855
SDR family oxidoreductase;
46-117 4.24e-15

SDR family oxidoreductase;


Pssm-ID: 235628 [Multi-domain]  Cd Length: 582  Bit Score: 75.79  E-value: 4.24e-15
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 499747296  46 DGLDIFYREAGPADAPVVLLLHGFPTSSHMFRNLIPLLADRYHVIAPDYPGYGQSAAPdRGTYAYTFAGAAD 117
Cdd:PRK05855  11 DGVRLAVYEWGDPDRPTVVLVHGYPDNHEVWDGVAPLLADRFRVVAYDVRGAGRSSAP-KRTAAYTLARLAD 81
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
46-320 7.22e-12

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 64.27  E-value: 7.22e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296  46 DGLDI---FYREAGPADAPVVLLLHGFPTS-SHMFRNLIPLLADR-YHVIAPDYPGYGQSAapdRGTYAYTFAGAADIVD 120
Cdd:COG1506    6 DGTTLpgwLYLPADGKKYPVVVYVHGGPGSrDDSFLPLAQALASRgYAVLAPDYRGYGESA---GDWGGDEVDDVLAAID 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296 121 KLMVHLEAKSYAMYVM--DYGAPVGYRLALKHPERVSGLIIQNGNAYeegLKEFWDPIKTYwsdgsdksraalsglvtLE 198
Cdd:COG1506   83 YLAARPYVDPDRIGIYghSYGGYMALLAAARHPDRFKAAVALAGVSD---LRSYYGTTREY-----------------TE 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296 199 TTKFQYTDGMEDVSRISPDNWVHdqalldrpgnkdiqldmlydyrtNVplypdfqrffrerKPPTLIVWGKNDYIFPEAG 278
Cdd:COG1506  143 RLMGGPWEDPEAYAARSPLAYAD-----------------------KL-------------KTPLLLIHGEADDRVPPEQ 186

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 499747296 279 AHPYLKDL----PDAEIHIL-NSGHFLLEEKLDVAAPLINDFLDRNV 320
Cdd:COG1506  187 AERLYEALkkagKPVELLVYpGEGHGFSGAGAPDYLERILDFLDRHL 233
PLN02824 PLN02824
hydrolase, alpha/beta fold family protein
 31-318 7.75e-10

hydrolase, alpha/beta fold family protein


Pssm-ID: 178419 [Multi-domain]  Cd Length: 294  Bit Score: 58.98  E-value: 7.75e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296  31 DRQAPAPVHYRTAKIDGLDIFYREAGPaDAPVVLLLHGFPTSSHMFRNLIPLLADRYHVIAPDYPGYGQSAAPD----RG 106
Cdd:PLN02824   1 TVKPEPQVETRTWRWKGYNIRYQRAGT-SGPALVLVHGFGGNADHWRKNTPVLAKSHRVYAIDLLGYGYSDKPNprsaPP 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296 107 TYAYTFAGAADIVDKLMVHLeAKSYAMYVMD-YGAPVGYRLALKHPERVSGLIIQNGNAyeEGL---KEFW--DP-IKTY 179
Cdd:PLN02824  80 NSFYTFETWGEQLNDFCSDV-VGDPAFVICNsVGGVVGLQAAVDAPELVRGVMLINISL--RGLhikKQPWlgRPfIKAF 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296 180 WS--DGSDKSRAALSGLVTLETTKFQYTDGMEDVSRISpDNWVhdQALLD---RPGNKDIQLDML-YdyrTNVPLyPdfQ 253
Cdd:PLN02824 157 QNllRETAVGKAFFKSVATPETVKNILCQCYHDDSAVT-DELV--EAILRpglEPGAVDVFLDFIsY---SGGPL-P--E 227

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 499747296 254 RFFRERKPPTLIVWGKNDYIFPEAGAHPYLK-DLPDAEIHILNSGHFLLEEKLDVAAPLINDFLDR 318
Cdd:PLN02824 228 ELLPAVKCPVLIAWGEKDPWEPVELGRAYANfDAVEDFIVLPGVGHCPQDEAPELVNPLIESFVAR 293
PLN02894 PLN02894
hydrolase, alpha/beta fold family protein
 56-159 5.07e-08

hydrolase, alpha/beta fold family protein


Pssm-ID: 215484 [Multi-domain]  Cd Length: 402  Bit Score: 53.76  E-value: 5.07e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296  56 GPADAPVVLLLHGFPTS-SHMFRNLiPLLADRYHVIAPDYPGYGQSAAPDRgTYAYTFAGAADIVDKLMVHLEAKSYAMY 134
Cdd:PLN02894 101 SKEDAPTLVMVHGYGASqGFFFRNF-DALASRFRVIAIDQLGWGGSSRPDF-TCKSTEETEAWFIDSFEEWRKAKNLSNF 178

                         90       100
                 ....*....|....*....|....*...
gi 499747296 135 VM---DYGAPVGYRLALKHPERVSGLII 159
Cdd:PLN02894 179 ILlghSFGGYVAAKYALKHPEHVQHLIL 206
bioH TIGR01738
pimelyl-[acyl-carrier protein] methyl ester esterase; This CoA-binding enzyme is required for ...
 61-298 9.76e-08

pimelyl-[acyl-carrier protein] methyl ester esterase; This CoA-binding enzyme is required for the production of pimeloyl-coenzyme A, the substrate of the BioF protein early in the biosynthesis of biotin. Its exact function is unknown, but is proposed in ref 2. This enzyme belongs to the alpha/beta hydrolase fold family (pfam00561). Members of this family are restricted to the Proteobacteria. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin]


Pssm-ID: 273783 [Multi-domain]  Cd Length: 245  Bit Score: 52.13  E-value: 9.76e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296   61 PVVLLLHGFPTSSHMFRNLIPLLADRYHVIAPDYPGYGQSAapdrgtyAYTFAGAADIVDKLMVHLEAKsyAMYV-MDYG 139
Cdd:TIGR01738   5 VHLVLIHGWGMNAEVFRCLDEELSAHFTLHLVDLPGHGRSR-------GFGPLSLADMAEAIAAQAPDP--AIWLgWSLG 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296  140 APVGYRLALKHPERVSGLIIQNGNA-------YEEGLKEfwDPIKTYWSDGSDKSRAALSGLVTLETTKFQYTDGmeDVS 212
Cdd:TIGR01738  76 GLVALHIAATHPDRVRALVTVASSPcfsaredWPEGIKP--DVLTGFQQQLSDDYQRTIERFLALQTLGTPTARQ--DAR 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296  213 RISPDnwvhdqaLLDR--PGNKDIQ--LDMLYDYrtnvplypDFQRFFRERKPPTLIVWGKNDYIFPEAGAHPYLKDLPD 288
Cdd:TIGR01738 152 ALKQT-------LLARptPNVQVLQagLEILATV--------DLRQPLQNISVPFLRLYGYLDGLVPAKVVPMLDKLAPH 216

                         250
                  ....*....|.
gi 499747296  289 AEIHILN-SGH 298
Cdd:TIGR01738 217 SELYIFAkAAH 227
Abhydrolase_6 pfam12697
Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse ...
 63-309 1.13e-07

Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse specificity.


Pssm-ID: 463673 [Multi-domain]  Cd Length: 211  Bit Score: 51.71  E-value: 1.13e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296   63 VLLLHGFPtssHMFRNLIPLLADRYHVIAPDYPGYGQSAAPDrgtyaYTFAGAADIVDkLMVHLEAKSYAMYVM-DYGAP 141
Cdd:pfam12697   1 VVLVHGAG---LSAAPLAALLAAGVAVLAPDLPGHGSSSPPP-----LDLADLADLAA-LLDELGAARPVVLVGhSLGGA 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296  142 VGYRLAlkHPERVSGLIIqngnayeeglkefwDPIKTYWSDGSDKSRAALSGLVTLETTKFQYTDGMedvsrispdnwvh 221
Cdd:pfam12697  72 VALAAA--AAALVVGVLV--------------APLAAPPGLLAALLALLARLGAALAAPAWLAAESL------------- 122

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296  222 DQALLDRPGNKDIQLDMLYDYRTNVP-LYPDFQRFFRERKPPTLIVWGKNDYIFPEAGAhpYLKDLPDAEIHIL-NSGHF 299
Cdd:pfam12697 123 ARGFLDDLPADAEWAAALARLAALLAaLALLPLAAWRDLPVPVLVLAEEDRLVPELAQR--LLAALAGARLVVLpGAGHL 200

                         250
                  ....*....|
gi 499747296  300 LLEEKLDVAA 309
Cdd:pfam12697 201 PLDDPEEVAE 210
YvaK COG1647
Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];
51-321 3.79e-07

Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 441253 [Multi-domain]  Cd Length: 246  Bit Score: 50.33  E-value: 3.79e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296  51 FYREAGPadaPVVLLLHGFPTSSHMFRNLIPLLADR-YHVIAPDYPGYGQSAAPDRGTyayTFAGAADIVDKLMVHLEAK 129
Cdd:COG1647    9 FFLEGGR---KGVLLLHGFTGSPAEMRPLAEALAKAgYTVYAPRLPGHGTSPEDLLKT---TWEDWLEDVEEAYEILKAG 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296 130 SYAMYVMDY--GAPVGYRLALKHPErVSGLIIQNGNAYEEGLKEFWDPIKTYWSDgsdksraalsglvtlettkfqytdg 207
Cdd:COG1647   83 YDKVIVIGLsmGGLLALLLAARYPD-VAGLVLLSPALKIDDPSAPLLPLLKYLAR------------------------- 136

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296 208 medvsrispdnWVHDQalldRPGNKDIQLDMLYDYRTNVPLYPDFQRFFRERKP-------PTLIVWGKNDYIFPEAGAH 280
Cdd:COG1647  137 -----------SLRGI----GSDIEDPEVAEYAYDRTPLRALAELQRLIREVRRdlpkitaPTLIIQSRKDEVVPPESAR 201

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 499747296 281 PYLKDL--PDAEIHIL-NSGHFL-LEEKLDVAAPLINDFLDRNVA 321
Cdd:COG1647  202 YIYERLgsPDKELVWLeDSGHVItLDKDREEVAEEILDFLERLAA 246
PLN02980 PLN02980
2-oxoglutarate decarboxylase/ hydro-lyase/ magnesium ion binding / thiamin pyrophosphate ...
 53-191 5.31e-07

2-oxoglutarate decarboxylase/ hydro-lyase/ magnesium ion binding / thiamin pyrophosphate binding


Pssm-ID: 215530 [Multi-domain]  Cd Length: 1655  Bit Score: 51.40  E-value: 5.31e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296   53 REAGP-ADAPVVLLLHGFPTSSHMFRNLIPLLADRYHVIAPDYPGYGQS-----AAPDRGTYAYTFAGAADIVDKLMVHL 126
Cdd:PLN02980 1363 HEVGQnAEGSVVLFLHGFLGTGEDWIPIMKAISGSARCISIDLPGHGGSkiqnhAKETQTEPTLSVELVADLLYKLIEHI 1442

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 499747296  127 EAKSYAMYVMDYGAPVGYRLALKHPERVSGLIIQNGNAyeeGLKefwDPIKTYWSDGSDKSRAAL 191
Cdd:PLN02980 1443 TPGKVTLVGYSMGARIALYMALRFSDKIEGAVIISGSP---GLK---DEVARKIRSAKDDSRARM 1501
PRK11126 PRK11126
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase; Provisional
 59-163 1.32e-06

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase; Provisional


Pssm-ID: 236855 [Multi-domain]  Cd Length: 242  Bit Score: 48.68  E-value: 1.32e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296  59 DAPVVLLLHGFPTSSHMFRNLIPLLADrYHVIAPDYPGYGQSAapdrgtyAYTFAGAADIVDKLMVHLEAKSYAMYVMdy 138
Cdd:PRK11126   1 GLPWLVFLHGLLGSGQDWQPVGEALPD-YPRLYIDLPGHGGSA-------AISVDGFADVSRLLSQTLQSYNILPYWL-- 70

                         90       100       110
                 ....*....|....*....|....*....|....
gi 499747296 139 gapVGY----RLALKH-----PERVSGLIIQNGN 163
Cdd:PRK11126  71 ---VGYslggRIAMYYacqglAGGLCGLIVEGGN 101
PRK10349 PRK10349
pimeloyl-ACP methyl ester esterase BioH;
49-158 8.98e-06

pimeloyl-ACP methyl ester esterase BioH;


Pssm-ID: 137836 [Multi-domain]  Cd Length: 256  Bit Score: 46.16  E-value: 8.98e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296  49 DIFYREAGPADAPVVLLlHGFPTSSHMFRNLIPLLADRYHVIAPDYPGYGQSaapdRGTYAYTFAGAADIVDKlmvhlEA 128
Cdd:PRK10349   3 NIWWQTKGQGNVHLVLL-HGWGLNAEVWRCIDEELSSHFTLHLVDLPGFGRS----RGFGALSLADMAEAVLQ-----QA 72

                         90       100       110
                 ....*....|....*....|....*....|.
gi 499747296 129 KSYAMYV-MDYGAPVGYRLALKHPERVSGLI 158
Cdd:PRK10349  73 PDKAIWLgWSLGGLVASQIALTHPERVQALV 103
PLN02679 PLN02679
hydrolase, alpha/beta fold family protein
 1-119 1.08e-05

hydrolase, alpha/beta fold family protein


Pssm-ID: 178283 [Multi-domain]  Cd Length: 360  Bit Score: 46.37  E-value: 1.08e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296   1 MRRLIICLMLAAASMTATTIASAVPAHATADRQAPAPVHYR-TAKIDGLDIFYREAGPADAPVvLLLHGFPTSSHMFRNL 79
Cdd:PLN02679  29 LRRDRACVRATASGSTAVSSSGGVEAELEEIYERCKKWKWKgEYSINYLVKGSPEVTSSGPPV-LLVHGFGASIPHWRRN 107

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 499747296  80 IPLLADRYHVIAPDYPGYGQSAAPDRgtYAYTFAGAADIV 119
Cdd:PLN02679 108 IGVLAKNYTVYAIDLLGFGASDKPPG--FSYTMETWAELI 145
PRK08775 PRK08775
homoserine O-succinyltransferase;
8-162 7.62e-05

homoserine O-succinyltransferase;


Pssm-ID: 181553 [Multi-domain]  Cd Length: 343  Bit Score: 44.01  E-value: 7.62e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296   8 LMLAAASMTATTIASAVPAHA--TADRQAPA-PVHYRTAKIDGLDIFYREAGPADAPVVLLLHGFPTSSHMFRNLI---- 80
Cdd:PRK08775   3 LVNTASPSTTLCVDTPTPDDDgpPAVRGEVAiPLSMRHAGLEDLRLRYELIGPAGAPVVFVAGGISAHRHVAATATfpek 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296  81 -----------PLLADRYHVIAPDYPGYGQSAAPDRGTYAYTFAGAAdIVDKLMVhleAKSYAMYVMDYGAPVGYRLALK 149
Cdd:PRK08775  83 gwweglvgsgrALDPARFRLLAFDFIGADGSLDVPIDTADQADAIAL-LLDALGI---ARLHAFVGYSYGALVGLQFASR 158

                        170
                 ....*....|...
gi 499747296 150 HPERVSGLIIQNG 162
Cdd:PRK08775 159 HPARVRTLVVVSG 171
FrsA COG1073
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms]; ...
 37-120 1.32e-04

Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms];


Pssm-ID: 440691 [Multi-domain]  Cd Length: 253  Bit Score: 42.59  E-value: 1.32e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296  37 PVHYRTAkiDGLDI---FYREAGPADA-PVVLLLHGFPTSSHMFRNLIPLLADR-YHVIAPDYPGYGQS-------AAPD 104
Cdd:COG1073   12 DVTFKSR--DGIKLagdLYLPAGASKKyPAVVVAHGNGGVKEQRALYAQRLAELgFNVLAFDYRGYGESegepreeGSPE 89

                         90
                 ....*....|....*...
gi 499747296 105 RGTY--AYTFAGAADIVD 120
Cdd:COG1073   90 RRDAraAVDYLRTLPGVD 107
Ndr pfam03096
Ndr family; This family consists of proteins from different gene families: Ndr1/RTP/Drg1, Ndr2, ...
 86-161 2.78e-04

Ndr family; This family consists of proteins from different gene families: Ndr1/RTP/Drg1, Ndr2, and Ndr3. Their similarity was previously noted. The precise molecular and cellular function of members of this family is still unknown. Yet, they are known to be involved in cellular differentiation events. The Ndr1 group was the first to be discovered. Their expression is repressed by the proto-oncogenes N-myc and c-myc, and in line with this observation, Ndr1 protein expression is down-regulated in neoplastic cells, and is reactivated when differentiation is induced by chemicals such as retinoic acid. Ndr2 and Ndr3 expression is not under the control of N-myc or c-myc. Ndr1 expression is also activated by several chemicals: tunicamycin and homocysteine induce Ndr1 in human umbilical endothelial cells; nickel induces Ndr1 in several cell types. Members of this family are found in wide variety of multicellular eukaryotes, including an Ndr1 type protein in Helianthus annuus (sunflower), known as Sf21. Interestingly, the highest scoring matches in the noise are all alpha/beta hydrolases pfam00561, suggesting that this family may have an enzymatic function (Bateman A pers. obs.).


Pssm-ID: 397285 [Multi-domain]  Cd Length: 285  Bit Score: 41.95  E-value: 2.78e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296   86 RYHViapDYPGYGQSAAPDRGTYAY-TFAGAADIVDKLMVHLEAKsyamYVMDYGAPVG----YRLALKHPERVSGLIIQ 160
Cdd:pfam03096  58 IYHV---DAPGQEDGAASFPGGYPYpSMDDLADMLPVVLDHFRLK----SVIGMGVGAGayilARFALKHPERVEGLVLI 130


                  .
gi 499747296  161 N 161
Cdd:pfam03096 131 N 131
PLN02578 PLN02578
hydrolase
 2-161 2.92e-04

hydrolase


Pssm-ID: 215315 [Multi-domain]  Cd Length: 354  Bit Score: 42.14  E-value: 2.92e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296   2 RRLIICLMLAAASMTATTIASAVPAHATADRQAPAPVHYRTAKIDGLDIFYREAGpaDAPVVLLLHGFPTSSHMFRNLIP 81
Cdd:PLN02578  30 RRIFIFGGIVASGVSVMGSSSASQSVQGLERLPFKKEGYNFWTWRGHKIHYVVQG--EGLPIVLIHGFGASAFHWRYNIP 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296  82 LLADRYHVIAPDYPGYGQSaapdrgtyaytfagaadivDKLMVHLEAKSYAMYVMDY-----GAP---VGYRL------- 146
Cdd:PLN02578 108 ELAKKYKVYALDLLGFGWS-------------------DKALIEYDAMVWRDQVADFvkevvKEPavlVGNSLggftals 168

                        170
                 ....*....|....*.
gi 499747296 147 -ALKHPERVSGLIIQN 161
Cdd:PLN02578 169 tAVGYPELVAGVALLN 184
PLN03087 PLN03087
BODYGUARD 1 domain containing hydrolase; Provisional
 50-157 3.18e-04

BODYGUARD 1 domain containing hydrolase; Provisional


Pssm-ID: 215567  Cd Length: 481  Bit Score: 42.10  E-value: 3.18e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296  50 IFYREAGPADAPV---VLLLHGFPTSS-----HMFRNLIPLLADRYHVIAPDYPGYGQSAAPDRGTyaYTFAGAADIVDK 121
Cdd:PLN03087 188 LFVHVQQPKDNKAkedVLFIHGFISSSafwteTLFPNFSDAAKSTYRLFAVDLLGFGRSPKPADSL--YTLREHLEMIER 265

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 499747296 122 LMVH-LEAKSYAMYVMDYGAPVGYRLALKHPERVSGL 157
Cdd:PLN03087 266 SVLErYKVKSFHIVAHSLGCILALALAVKHPGAVKSL 302
PRK06489 PRK06489
hypothetical protein; Provisional
 7-120 2.98e-03

hypothetical protein; Provisional


Pssm-ID: 235815 [Multi-domain]  Cd Length: 360  Bit Score: 38.81  E-value: 2.98e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296   7 CLMLAAASMTATTIASAVPAHATADRQAP-------APVHYRT-AKIDGLDIFY-------REAGPADAPVVLLLHGFPT 71
Cdd:PRK06489   1 VNRLLLTLLAALLLPLSVSAAAAAAYPAPqegdwvaRDFTFHSgETLPELRLHYttlgtphRNADGEIDNAVLVLHGTGG 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 499747296  72 S-SHMFRNLI---------PLLADRYHVIAPDYPGYGQSAAPDRGTYA----YTFagaADIVD 120
Cdd:PRK06489  81 SgKSFLSPTFagelfgpgqPLDASKYFIILPDGIGHGKSSKPSDGLRAafprYDY---DDMVE 140
COG4188 COG4188
Predicted dienelactone hydrolase [General function prediction only];
8-96 3.24e-03

Predicted dienelactone hydrolase [General function prediction only];


Pssm-ID: 443342 [Multi-domain]  Cd Length: 326  Bit Score: 38.93  E-value: 3.24e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499747296   8 LMLAAASMTATTIASAVPAHATADRQAPAPVHYRTAKIDG---LDIFYREAGPADA------PVVLLLHGFPTSSHMFRN 78
Cdd:COG4188    1 LLALLALLLAAAAAASPLRQPGPFAVGVQTLTLRDPSRDRplpVDVWYPATAPADApaggpfPLVVLSHGLGGSREGYAY 80

                         90
                 ....*....|....*....
gi 499747296  79 LIPLLADR-YHVIAPDYPG 96
Cdd:COG4188   81 LAEHLASHgYVVAAPDHPG 99
EstA COG1075
Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and ...
 58-100 5.98e-03

Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and metabolism];


Pssm-ID: 440693 [Multi-domain]  Cd Length: 106  Bit Score: 35.96  E-value: 5.98e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 499747296  58 ADAPVVLLLHGFPTSSHMFRNLIPLLADR-YHVIAPDYPGYGQS 100
Cdd:COG1075    3 ATRYPVVLVHGLGGSAASWAPLAPRLRAAgYPVYALNYPSTNGS 46
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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