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Conserved domains on  [gi|496673430|ref|WP_009315920|]
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MULTISPECIES: Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA [Pseudomonas]

Protein Classification

amidase( domain architecture ID 10000643)

amidase catalyzes the hydrolysis of a monocarboxylic acid amide to form a monocarboxylate and ammonia; similar to aspartyl/glutamyl-tRNA synthase subunit A (GatA), which is part of a heterotrimeric complex that forms correctly charged Gln-tRNA(Gln) or Asn-tRNA(Asn) through the transamidation of misacylated Glu-tRNA(Gln) or Asp-tRNA(Asn)

CATH:  3.90.1300.10
Gene Ontology:  GO:0003824
SCOP:  3001251|4002446

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GatA COG0154
Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase [Translation, ribosomal ...
 2-482 0e+00

Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase [Translation, ribosomal structure and biogenesis]; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases


:

Pssm-ID: 439924 [Multi-domain]  Cd Length: 468  Bit Score: 614.08  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430   2 LHQLTLAEIARALADKQFSAEELTRTLLGRIRQLDPQLNSFISITDDLAIAQAKAADERRANGEN-GALLGAPIAHKDLF 80
Cdd:COG0154    4 LAELSAAELAAALRAGEVSAVELVEAALARIEAVNPALNAFVTVDAERALAEARAADARRAAGEAlGPLAGVPVAVKDLI 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430  81 CTQGVRTSCGSKMLDNFVSPYDATVVEKLTAAGAVTLGKLNMDEFAMGSSNQSSHYGAVNNPWSLDRVP----------- 149
Cdd:COG0154   84 DVAGLPTTAGSKALADFVPPYDATVVARLRAAGAVILGKTNMPEFAMGGSTENSAYGPTRNPWDPDRTPggssggsaaav 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 150 -GgssggsaaavaaRLLPAATGTDTGGSIRQPAALTNLTGIKPTYGRVSRWGMIAYASSLDQGGPLARTAEDCALMLGVM 228
Cdd:COG0154  164 aA------------GLVPLALGSDTGGSIRIPAAFCGLVGLKPTYGRVSRYGVVPLASSLDQVGPLARTVADAALLLDVL 231

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 229 AGFDPKDSTSVEQPVDDYLAALQKPLSGLRIGLPREYFG-AGLDSRIADAVLAVVEELKTLGATVKDISLPNMQHAIPAY 307
Cdd:COG0154  232 AGPDPRDPTSAPAPVPDYLAALDRDLKGLRIGVPREYFGgDGVDPEVAAAVEAAAAALEALGAEVVEVDLPDLDEALAAY 311

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 308 YVIAPAEASSnlsrfdgvrygyrcdapqNLEDLYkRSRAEGFGSEVKNRIMVGTYalsagYYDAYYLQAQKIRRLIKNDF 387
Cdd:COG0154  312 YTIAAAEAAA------------------NLADLL-RTRPEGFGPEVRRRILLGAY-----YSAADYLKAQRVRALLRRDF 367

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 388 VSAFAEVDVILGPTTPNPAWKIGEKN---DDPVS-QYLEDIYTITANLAGLPGLSMPAGFV-DGLPVGVQLLAPYFQEGR 462
Cdd:COG0154  368 AAAFEDYDVLLTPTTPTPAPPIGELDadiDPALAmNYLLDRFTAPANLAGLPALSVPAGFTaDGLPVGLQLIGPPGDEAT 447

                        490       500
                 ....*....|....*....|
gi 496673430 463 LLNVAHQYQQVSDWHTRTPA 482
Cdd:COG0154  448 LLRLAAALEQALGWHRRRPP 467
 
Name Accession Description Interval E-value
GatA COG0154
Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase [Translation, ribosomal ...
 2-482 0e+00

Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase [Translation, ribosomal structure and biogenesis]; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases


Pssm-ID: 439924 [Multi-domain]  Cd Length: 468  Bit Score: 614.08  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430   2 LHQLTLAEIARALADKQFSAEELTRTLLGRIRQLDPQLNSFISITDDLAIAQAKAADERRANGEN-GALLGAPIAHKDLF 80
Cdd:COG0154    4 LAELSAAELAAALRAGEVSAVELVEAALARIEAVNPALNAFVTVDAERALAEARAADARRAAGEAlGPLAGVPVAVKDLI 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430  81 CTQGVRTSCGSKMLDNFVSPYDATVVEKLTAAGAVTLGKLNMDEFAMGSSNQSSHYGAVNNPWSLDRVP----------- 149
Cdd:COG0154   84 DVAGLPTTAGSKALADFVPPYDATVVARLRAAGAVILGKTNMPEFAMGGSTENSAYGPTRNPWDPDRTPggssggsaaav 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 150 -GgssggsaaavaaRLLPAATGTDTGGSIRQPAALTNLTGIKPTYGRVSRWGMIAYASSLDQGGPLARTAEDCALMLGVM 228
Cdd:COG0154  164 aA------------GLVPLALGSDTGGSIRIPAAFCGLVGLKPTYGRVSRYGVVPLASSLDQVGPLARTVADAALLLDVL 231

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 229 AGFDPKDSTSVEQPVDDYLAALQKPLSGLRIGLPREYFG-AGLDSRIADAVLAVVEELKTLGATVKDISLPNMQHAIPAY 307
Cdd:COG0154  232 AGPDPRDPTSAPAPVPDYLAALDRDLKGLRIGVPREYFGgDGVDPEVAAAVEAAAAALEALGAEVVEVDLPDLDEALAAY 311

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 308 YVIAPAEASSnlsrfdgvrygyrcdapqNLEDLYkRSRAEGFGSEVKNRIMVGTYalsagYYDAYYLQAQKIRRLIKNDF 387
Cdd:COG0154  312 YTIAAAEAAA------------------NLADLL-RTRPEGFGPEVRRRILLGAY-----YSAADYLKAQRVRALLRRDF 367

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 388 VSAFAEVDVILGPTTPNPAWKIGEKN---DDPVS-QYLEDIYTITANLAGLPGLSMPAGFV-DGLPVGVQLLAPYFQEGR 462
Cdd:COG0154  368 AAAFEDYDVLLTPTTPTPAPPIGELDadiDPALAmNYLLDRFTAPANLAGLPALSVPAGFTaDGLPVGLQLIGPPGDEAT 447

                        490       500
                 ....*....|....*....|
gi 496673430 463 LLNVAHQYQQVSDWHTRTPA 482
Cdd:COG0154  448 LLRLAAALEQALGWHRRRPP 467
gatA TIGR00132
aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit; In many species, Gln--tRNA ligase ...
 10-472 0e+00

aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit; In many species, Gln--tRNA ligase is missing. tRNA(Gln) is misacylated with Glu after which a heterotrimeric amidotransferase converts Glu to Gln. This model represents the amidase chain of that heterotrimer, encoded by the gatA gene. In the Archaea, Asn--tRNA ligase is also missing. This amidase subunit may also function in the conversion of Asp-tRNA(Asn) to Asn-tRNA(Asn), presumably with a different recognition unit to replace gatB. Both Methanococcus jannaschii and Methanobacterium thermoautotrophicum have both authentic gatB and a gatB-related gene, but only one gene like gatA. It has been shown that gatA can be expressed only when gatC is also expressed. In most species expressing the amidotransferase, the gatC ortholog is about 90 residues in length, but in Mycoplasma genitalium and Mycoplasma pneumoniae the gatC equivalent is as the C-terminal domain of a much longer protein. Not surprisingly, the Mycoplasmas also represent the most atypical lineage of gatA orthology. This orthology group is more narrowly defined here than in Proc Natl Acad Aci USA 94, 11819-11826 (1997). In particular, a Rhodococcus homolog found in association with nitrile hydratase genes and described as an enantiomer-selective amidase active on several 2-aryl propionamides, is excluded here. It is likely, however, that the amidase subunit GatA is not exclusively a part of the Glu-tRNA(Gln) amidotransferase heterotrimer and restricted to that function in all species. [Protein synthesis, tRNA aminoacylation]


Pssm-ID: 272925 [Multi-domain]  Cd Length: 460  Bit Score: 579.29  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430   10 IARALADKQFSAEELTRTLLGRIRQLDPQLNSFISITDDLAIAQAKAADERrangENGALLGAPIAHKDLFCTQGVRTSC 89
Cdd:TIGR00132   1 LRQLLKKKEISIKEVLEASLDRIEANKDKINAFLEVTVEKALKQAKKLDKA----ILTPLAGIPIAVKDNISTKGIVTTC 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430   90 GSKMLDNFVSPYDATVVEKLTAAGAVTLGKLNMDEFAMGSSNQSSHYGAVNNPWSLDRVPGGSSGGSAAAVAARLLPAAT 169
Cdd:TIGR00132  77 ASKILENYIPPYDATVIERLKQAGALIIGKTNMDEFAMGSSTETSAFGPTKNPWNLDRVPGGSSGGSAAAVAADLAPFSL 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430  170 GTDTGGSIRQPAALTNLTGIKPTYGRVSRWGMIAYASSLDQGGPLARTAEDCALMLGVMAGFDPKDSTSVEQPVDDYLAA 249
Cdd:TIGR00132 157 GSDTGGSIRQPASFCGVVGFKPTYGRVSRYGLVAYASSLDQIGPFARTVEDIALLLDVISGHDKRDSTSAKVPDPEFFEE 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430  250 LQKPLSGLRIGLPREYFGAgLDSRIADAVLAVVEELKTLGATVKDISLPNMQHAIPAYYVIAPAEASSNLSRFDGVRYGY 329
Cdd:TIGR00132 237 LKKDLKGLKVGVVKEFSEE-MDKEVQEKFENALEVLEELGAEIVEVSFPHVKYALPIYYIISPSEASSNLARYDGIRYGY 315

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430  330 RCDAPQNLEDLYKRSRAEGFGSEVKNRIMVGTYALSAGYYDAYYLQAQKIRRLIKNDFVSAFAEVDVILGPTTPNPAWKI 409
Cdd:TIGR00132 316 RIEEPNSLKELYAKTRAEGFGEEVKRRIMLGNYALSAGYYDKYYLKAQKVRTLIIDDFLKLFEEVDVIVSPTAPTLPFKI 395

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 496673430  410 GEKNDDPVSQYLEDIYTITANLAGLPGLSMPAGFV-DGLPVGVQLLAPYFQEGRLLNVAHQYQQ 472
Cdd:TIGR00132 396 GEKLDDPLEMYLSDILTVPANLAGLPAISVPCGVKeKGLPIGLQIIGKCFDDKTLLQVSYAFEQ 459
Amidase pfam01425
Amidase;
23-464 0e+00

Amidase;


Pssm-ID: 396144 [Multi-domain]  Cd Length: 442  Bit Score: 518.01  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430   23 ELTRTLLGRIRQLDPQLNSFISITDDLAIAQAKAADERRANGE-NGALLGAPIAHKDLFCTQGVRTSCGSKMLDNFVSPY 101
Cdd:pfam01425   1 ELVEAFLDRIEAANPKLNAFVTVFFDEALAQAAAADKQRAAGDpKGPLHGVPIAVKDNIDVKGVPTTAGSKALENYPAPY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430  102 DATVVEKLTAAGAVTLGKLNMDEFAMGSSNQSSHYGAVNNPWSLDRVPGGSSGGSAAAVAARLLPAATGTDTGGSIRQPA 181
Cdd:pfam01425  81 DATVVERLRKAGAVILGKTNMDEFAMGSSTENSVFGPTRNPWDLSRTPGGSSGGSAAAVAAGLVPLAIGTDTGGSIRIPA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430  182 ALTNLTGIKPTYGRVSRWGMIAYASSLDQGGPLARTAEDCALMLGVMAGFDPKDSTSVEQPVDDYLAALQKPLSGLRIGL 261
Cdd:pfam01425 161 SFCGLVGLKPTYGRVSRYGVVGYASSLDQVGPLARSVEDAALLLRVISGYDPKDSTSLPPPVPDYAEPVKKSLKGLRIGV 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430  262 PREYFGAGLDSRIADAVLAVVEELKTLGATVKDISLPNMQHAIPAYYVIAPAEASSNLSRFDGVrygyrCDAPQNLEDLY 341
Cdd:pfam01425 241 YREDGYFDLDPEVRRAVEEALAQLEALGHEVVEVDPPSLDYALPLYYLIAPAEASSNLARYDGV-----PSGPDDLSELY 315

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430  342 KRSRAEGFGSEVKNRIMVGTYALSAGYYDAYYLQAQKIRRLIKNDFVSAFAEVDVILGPTTPNPAWKIGEKNDDPVSQYL 421
Cdd:pfam01425 316 PRTRAEGLGDEVKRRIILGNYALSAGYYDKYYLKAQKVRRLIRREFAGLFEELDVLLSPTAPTPAPRLGEPDDSPLVMYN 395

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*..
gi 496673430  422 EDIYT---ITANLAGLPGLSMPAGFV-DGLPVGVQLLAPYFQEGRLL 464
Cdd:pfam01425 396 LDDFTagvVPVNLAGLPAISLPAGFTaDGLPVGVQIIGKPGDEETLL 442
PRK09201 PRK09201
AtzE family amidohydrolase;
4-472 4.65e-97

AtzE family amidohydrolase;


Pssm-ID: 236409 [Multi-domain]  Cd Length: 465  Bit Score: 300.35  E-value: 4.65e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430   4 QLTLAEIARALADKQFSAEELTRTLLGRIRQLDPQLNSFISITDDLAIAQAKAADERRANGEN-GALLGAPIAHKDLFCT 82
Cdd:PRK09201   6 SLSAAEIAAAVRAGELSARAVAQATLARIARANPQLNAFTAVTAERALAEAARIDAARAAGEPlGPLAGVPFAVKNLFDV 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430  83 QGVRTSCGSKML-DNFVSPYDATVVEKLTAAGAVTLGKLNMDEFAMGSSNQSSHYGAVNNPWSLDRVPGGSSGGSAAAVA 161
Cdd:PRK09201  86 AGLTTLAGSKINrDRPPATRDATAVRRLEAAGAVLVGALNMDEYAYGFTTENSHYGATRNPHDLTRIAGGSSGGSAAAVA 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 162 ARLLPAATGTDTGGSIRQPAALTNLTGIKPTYGRVSRWGMIAYASSLDQGGPLARTAEDCALMLGVMAGFDPKDSTSVEQ 241
Cdd:PRK09201 166 AGLVPFTLGSDTNGSIRVPASLCGIFGLKPTYGRLSRAGSFPFVASLDHIGPFARSVADLALVYDVLQGPDPQDPFQADR 245

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 242 PVDDYLAALQKPLSGLRIGLPREYFGAGLDSRIADAVLAVveeLKTLGATvKDISLPNMQHAIPAYYVIAPAEASSnlsr 321
Cdd:PRK09201 246 PAEPTAPLLDRGAEGLRIAVLGGYFAQWADPEARAAVDRV---AKALGAT-REVELPEAARARAAAFIITASEGGN---- 317

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 322 fdgvrygyrcdapQNLEDLykRSRAEGFGSEVKNRIMVGTyALSAgyydAYYLQAQKIRRLIKNDFVSAFAEVDVILGPT 401
Cdd:PRK09201 318 -------------LHLPAL--RTRPQDFDPASRDRLLAGA-MLPA----AWYVQAQRFRRWFRQAVLELFEHVDVLIAPA 377

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 496673430 402 TPNPAWKIGEKN------DDPVSQYLeDIYTITANLAGLPGLSMPAGFVDGLPVGVQLLAPYFQEGRLLNVAHQYQQ 472
Cdd:PRK09201 378 TPCSAPLIGQETmridgvELPVRANL-GILTQPISFIGLPVVAVPLRTPGGLPIGVQLIAAPWREDLALRAAAALEQ 453
 
Name Accession Description Interval E-value
GatA COG0154
Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase [Translation, ribosomal ...
 2-482 0e+00

Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase [Translation, ribosomal structure and biogenesis]; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases


Pssm-ID: 439924 [Multi-domain]  Cd Length: 468  Bit Score: 614.08  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430   2 LHQLTLAEIARALADKQFSAEELTRTLLGRIRQLDPQLNSFISITDDLAIAQAKAADERRANGEN-GALLGAPIAHKDLF 80
Cdd:COG0154    4 LAELSAAELAAALRAGEVSAVELVEAALARIEAVNPALNAFVTVDAERALAEARAADARRAAGEAlGPLAGVPVAVKDLI 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430  81 CTQGVRTSCGSKMLDNFVSPYDATVVEKLTAAGAVTLGKLNMDEFAMGSSNQSSHYGAVNNPWSLDRVP----------- 149
Cdd:COG0154   84 DVAGLPTTAGSKALADFVPPYDATVVARLRAAGAVILGKTNMPEFAMGGSTENSAYGPTRNPWDPDRTPggssggsaaav 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 150 -GgssggsaaavaaRLLPAATGTDTGGSIRQPAALTNLTGIKPTYGRVSRWGMIAYASSLDQGGPLARTAEDCALMLGVM 228
Cdd:COG0154  164 aA------------GLVPLALGSDTGGSIRIPAAFCGLVGLKPTYGRVSRYGVVPLASSLDQVGPLARTVADAALLLDVL 231

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 229 AGFDPKDSTSVEQPVDDYLAALQKPLSGLRIGLPREYFG-AGLDSRIADAVLAVVEELKTLGATVKDISLPNMQHAIPAY 307
Cdd:COG0154  232 AGPDPRDPTSAPAPVPDYLAALDRDLKGLRIGVPREYFGgDGVDPEVAAAVEAAAAALEALGAEVVEVDLPDLDEALAAY 311

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 308 YVIAPAEASSnlsrfdgvrygyrcdapqNLEDLYkRSRAEGFGSEVKNRIMVGTYalsagYYDAYYLQAQKIRRLIKNDF 387
Cdd:COG0154  312 YTIAAAEAAA------------------NLADLL-RTRPEGFGPEVRRRILLGAY-----YSAADYLKAQRVRALLRRDF 367

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 388 VSAFAEVDVILGPTTPNPAWKIGEKN---DDPVS-QYLEDIYTITANLAGLPGLSMPAGFV-DGLPVGVQLLAPYFQEGR 462
Cdd:COG0154  368 AAAFEDYDVLLTPTTPTPAPPIGELDadiDPALAmNYLLDRFTAPANLAGLPALSVPAGFTaDGLPVGLQLIGPPGDEAT 447

                        490       500
                 ....*....|....*....|
gi 496673430 463 LLNVAHQYQQVSDWHTRTPA 482
Cdd:COG0154  448 LLRLAAALEQALGWHRRRPP 467
gatA TIGR00132
aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit; In many species, Gln--tRNA ligase ...
 10-472 0e+00

aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit; In many species, Gln--tRNA ligase is missing. tRNA(Gln) is misacylated with Glu after which a heterotrimeric amidotransferase converts Glu to Gln. This model represents the amidase chain of that heterotrimer, encoded by the gatA gene. In the Archaea, Asn--tRNA ligase is also missing. This amidase subunit may also function in the conversion of Asp-tRNA(Asn) to Asn-tRNA(Asn), presumably with a different recognition unit to replace gatB. Both Methanococcus jannaschii and Methanobacterium thermoautotrophicum have both authentic gatB and a gatB-related gene, but only one gene like gatA. It has been shown that gatA can be expressed only when gatC is also expressed. In most species expressing the amidotransferase, the gatC ortholog is about 90 residues in length, but in Mycoplasma genitalium and Mycoplasma pneumoniae the gatC equivalent is as the C-terminal domain of a much longer protein. Not surprisingly, the Mycoplasmas also represent the most atypical lineage of gatA orthology. This orthology group is more narrowly defined here than in Proc Natl Acad Aci USA 94, 11819-11826 (1997). In particular, a Rhodococcus homolog found in association with nitrile hydratase genes and described as an enantiomer-selective amidase active on several 2-aryl propionamides, is excluded here. It is likely, however, that the amidase subunit GatA is not exclusively a part of the Glu-tRNA(Gln) amidotransferase heterotrimer and restricted to that function in all species. [Protein synthesis, tRNA aminoacylation]


Pssm-ID: 272925 [Multi-domain]  Cd Length: 460  Bit Score: 579.29  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430   10 IARALADKQFSAEELTRTLLGRIRQLDPQLNSFISITDDLAIAQAKAADERrangENGALLGAPIAHKDLFCTQGVRTSC 89
Cdd:TIGR00132   1 LRQLLKKKEISIKEVLEASLDRIEANKDKINAFLEVTVEKALKQAKKLDKA----ILTPLAGIPIAVKDNISTKGIVTTC 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430   90 GSKMLDNFVSPYDATVVEKLTAAGAVTLGKLNMDEFAMGSSNQSSHYGAVNNPWSLDRVPGGSSGGSAAAVAARLLPAAT 169
Cdd:TIGR00132  77 ASKILENYIPPYDATVIERLKQAGALIIGKTNMDEFAMGSSTETSAFGPTKNPWNLDRVPGGSSGGSAAAVAADLAPFSL 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430  170 GTDTGGSIRQPAALTNLTGIKPTYGRVSRWGMIAYASSLDQGGPLARTAEDCALMLGVMAGFDPKDSTSVEQPVDDYLAA 249
Cdd:TIGR00132 157 GSDTGGSIRQPASFCGVVGFKPTYGRVSRYGLVAYASSLDQIGPFARTVEDIALLLDVISGHDKRDSTSAKVPDPEFFEE 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430  250 LQKPLSGLRIGLPREYFGAgLDSRIADAVLAVVEELKTLGATVKDISLPNMQHAIPAYYVIAPAEASSNLSRFDGVRYGY 329
Cdd:TIGR00132 237 LKKDLKGLKVGVVKEFSEE-MDKEVQEKFENALEVLEELGAEIVEVSFPHVKYALPIYYIISPSEASSNLARYDGIRYGY 315

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430  330 RCDAPQNLEDLYKRSRAEGFGSEVKNRIMVGTYALSAGYYDAYYLQAQKIRRLIKNDFVSAFAEVDVILGPTTPNPAWKI 409
Cdd:TIGR00132 316 RIEEPNSLKELYAKTRAEGFGEEVKRRIMLGNYALSAGYYDKYYLKAQKVRTLIIDDFLKLFEEVDVIVSPTAPTLPFKI 395

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 496673430  410 GEKNDDPVSQYLEDIYTITANLAGLPGLSMPAGFV-DGLPVGVQLLAPYFQEGRLLNVAHQYQQ 472
Cdd:TIGR00132 396 GEKLDDPLEMYLSDILTVPANLAGLPAISVPCGVKeKGLPIGLQIIGKCFDDKTLLQVSYAFEQ 459
Amidase pfam01425
Amidase;
23-464 0e+00

Amidase;


Pssm-ID: 396144 [Multi-domain]  Cd Length: 442  Bit Score: 518.01  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430   23 ELTRTLLGRIRQLDPQLNSFISITDDLAIAQAKAADERRANGE-NGALLGAPIAHKDLFCTQGVRTSCGSKMLDNFVSPY 101
Cdd:pfam01425   1 ELVEAFLDRIEAANPKLNAFVTVFFDEALAQAAAADKQRAAGDpKGPLHGVPIAVKDNIDVKGVPTTAGSKALENYPAPY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430  102 DATVVEKLTAAGAVTLGKLNMDEFAMGSSNQSSHYGAVNNPWSLDRVPGGSSGGSAAAVAARLLPAATGTDTGGSIRQPA 181
Cdd:pfam01425  81 DATVVERLRKAGAVILGKTNMDEFAMGSSTENSVFGPTRNPWDLSRTPGGSSGGSAAAVAAGLVPLAIGTDTGGSIRIPA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430  182 ALTNLTGIKPTYGRVSRWGMIAYASSLDQGGPLARTAEDCALMLGVMAGFDPKDSTSVEQPVDDYLAALQKPLSGLRIGL 261
Cdd:pfam01425 161 SFCGLVGLKPTYGRVSRYGVVGYASSLDQVGPLARSVEDAALLLRVISGYDPKDSTSLPPPVPDYAEPVKKSLKGLRIGV 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430  262 PREYFGAGLDSRIADAVLAVVEELKTLGATVKDISLPNMQHAIPAYYVIAPAEASSNLSRFDGVrygyrCDAPQNLEDLY 341
Cdd:pfam01425 241 YREDGYFDLDPEVRRAVEEALAQLEALGHEVVEVDPPSLDYALPLYYLIAPAEASSNLARYDGV-----PSGPDDLSELY 315

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430  342 KRSRAEGFGSEVKNRIMVGTYALSAGYYDAYYLQAQKIRRLIKNDFVSAFAEVDVILGPTTPNPAWKIGEKNDDPVSQYL 421
Cdd:pfam01425 316 PRTRAEGLGDEVKRRIILGNYALSAGYYDKYYLKAQKVRRLIRREFAGLFEELDVLLSPTAPTPAPRLGEPDDSPLVMYN 395

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*..
gi 496673430  422 EDIYT---ITANLAGLPGLSMPAGFV-DGLPVGVQLLAPYFQEGRLL 464
Cdd:pfam01425 396 LDDFTagvVPVNLAGLPAISLPAGFTaDGLPVGVQIIGKPGDEETLL 442
PRK09201 PRK09201
AtzE family amidohydrolase;
4-472 4.65e-97

AtzE family amidohydrolase;


Pssm-ID: 236409 [Multi-domain]  Cd Length: 465  Bit Score: 300.35  E-value: 4.65e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430   4 QLTLAEIARALADKQFSAEELTRTLLGRIRQLDPQLNSFISITDDLAIAQAKAADERRANGEN-GALLGAPIAHKDLFCT 82
Cdd:PRK09201   6 SLSAAEIAAAVRAGELSARAVAQATLARIARANPQLNAFTAVTAERALAEAARIDAARAAGEPlGPLAGVPFAVKNLFDV 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430  83 QGVRTSCGSKML-DNFVSPYDATVVEKLTAAGAVTLGKLNMDEFAMGSSNQSSHYGAVNNPWSLDRVPGGSSGGSAAAVA 161
Cdd:PRK09201  86 AGLTTLAGSKINrDRPPATRDATAVRRLEAAGAVLVGALNMDEYAYGFTTENSHYGATRNPHDLTRIAGGSSGGSAAAVA 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 162 ARLLPAATGTDTGGSIRQPAALTNLTGIKPTYGRVSRWGMIAYASSLDQGGPLARTAEDCALMLGVMAGFDPKDSTSVEQ 241
Cdd:PRK09201 166 AGLVPFTLGSDTNGSIRVPASLCGIFGLKPTYGRLSRAGSFPFVASLDHIGPFARSVADLALVYDVLQGPDPQDPFQADR 245

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 242 PVDDYLAALQKPLSGLRIGLPREYFGAGLDSRIADAVLAVveeLKTLGATvKDISLPNMQHAIPAYYVIAPAEASSnlsr 321
Cdd:PRK09201 246 PAEPTAPLLDRGAEGLRIAVLGGYFAQWADPEARAAVDRV---AKALGAT-REVELPEAARARAAAFIITASEGGN---- 317

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 322 fdgvrygyrcdapQNLEDLykRSRAEGFGSEVKNRIMVGTyALSAgyydAYYLQAQKIRRLIKNDFVSAFAEVDVILGPT 401
Cdd:PRK09201 318 -------------LHLPAL--RTRPQDFDPASRDRLLAGA-MLPA----AWYVQAQRFRRWFRQAVLELFEHVDVLIAPA 377

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 496673430 402 TPNPAWKIGEKN------DDPVSQYLeDIYTITANLAGLPGLSMPAGFVDGLPVGVQLLAPYFQEGRLLNVAHQYQQ 472
Cdd:PRK09201 378 TPCSAPLIGQETmridgvELPVRANL-GILTQPISFIGLPVVAVPLRTPGGLPIGVQLIAAPWREDLALRAAAALEQ 453
amido_AtzE TIGR02715
amidohydrolase, AtzE family; Members of this protein family are aminohydrolases related to, ...
 6-472 4.60e-92

amidohydrolase, AtzE family; Members of this protein family are aminohydrolases related to, but distinct from, glutamyl-tRNA(Gln) amidotransferase subunit A. The best characterized member is the biuret hydrolase of Pseudomonas sp. ADP, which hydrolyzes ammonia from the three-nitrogen compound biuret to yield allophanate. Allophanate is also an intermediate in urea degradation by the urea carboxylase/allophanate hydrolase pathway, an alternative to urease. [Unknown function, Enzymes of unknown specificity]


Pssm-ID: 274267 [Multi-domain]  Cd Length: 452  Bit Score: 287.07  E-value: 4.60e-92
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430    6 TLAEIARALADKQFSAEELTRTLLGRIRQLDPQLNSFISITDDLAIAQAKAADERRANGEN-GALLGAPIAHKDLFCTQG 84
Cdd:TIGR02715   1 SIVEIAGAIRSGRVSARAVAEATLARINQADGGLNAFTAVTAERALADAARIDADLAAGSPlGPLAGVPFAVKNLFDVAG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430   85 VRTSCGSKM-LDNFVSPYDATVVEKLTAAGAVTLGKLNMDEFAMGSSNQSSHYGAVNNPWSLDRVPGGSSGGSAAAVAAR 163
Cdd:TIGR02715  81 LTTLAGAKInRDLAPAKRDATLVQRLSAAGAVLVGALNMDEFAYGFTTENAHYGPTRNPHDLTRIAGGSSGGSAAAVAAG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430  164 LLPAATGTDTGGSIRQPAALTNLTGIKPTYGRVSRWGMIAYASSLDQGGPLARTAEDCALMLGVMAGFDPKDSTSVEQPV 243
Cdd:TIGR02715 161 LVPFSLGSDTNGSIRVPASLCGVFGLKPTYGRLSRQGVFPFVASLDHVGPFARSVEDLALAYDVMQGPDPQDPFCTDRPA 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430  244 DDYLAALQKPLSGLRIGLPREYFGAGLDSriaDAVLAVVEELKTLGATvKDISLPNMQHAIPAYYVIAPAEASSnlsrfd 323
Cdd:TIGR02715 241 EPTVPLLPAGISGLRIAVLGGWFQQNADP---EALAAVGRVAKALGAT-TIVELPDAERARAAAFVITASEGGN------ 310

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430  324 gvrygyrcdapQNLEDLykRSRAEGFGSEVKNRIMVGTYaLSAGYYDayylQAQKIRRLIKNDFVSAFAEVDVILGPTTP 403
Cdd:TIGR02715 311 -----------LHLDAL--RTRPQDFDPATRDRLLAGAL-LPASWYA----QAQRFRHWFRDAIRELFQRVDVLIAPATP 372

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 496673430  404 NPAWKIGEKN------DDPVSQYLeDIYTITANLAGLPGLSMPAGFVDGLPVGVQLLAPYFQEGRLLNVAHQYQQ 472
Cdd:TIGR02715 373 CSAPLIGQETmiidgvPVPVRANL-GIFTQPISFAGLPVLAAPLPRPGRLPIGVQLIAAPWREDLCLRAAAVLER 446
PRK07235 PRK07235
amidase; Provisional
 65-475 6.69e-86

amidase; Provisional


Pssm-ID: 235979 [Multi-domain]  Cd Length: 502  Bit Score: 272.65  E-value: 6.69e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430  65 ENGALLGAPIAHKDLFCTQGVRTSCGSKMLDNFVSPYDATVVEKLTAAGAVTLGKLNMDEFAMGSSNQSSHYGAVNNPWS 144
Cdd:PRK07235  84 AEGKLAGKTVALKDNVAVAGVPMMNGSSTLEGFVPSFDATVVTRLLDAGATIVGKATCEDLCFSGGSHTSDPGPVHNPRD 163

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 145 LDRVPGGSSGGSAAAVAARLLPAATGTDTGGSIRQPAALTNLTGIKPTYGRVSRWGMIAYASSLDQGGPLARTAEDCALM 224
Cdd:PRK07235 164 PGYSAGGSSSGSAALVAAGEVDMAIGGDQGGSIRIPSAWCGIYGMKPTHGLVPYTGAFPIERTIDHLGPMTATVRDNALL 243

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 225 LGVMAG---FDPKDSTSVeqPVDDYLAALQKPLSGLRIGLPREYFG-AGLDSRIADAVLAVVEELKTLGATVKDISLPNM 300
Cdd:PRK07235 244 LEVIAGrdgLDPRQPAQP--PVDDYTAALDRGVKGLKIGILREGFGlPNSEPEVDEAVRAAAKRLEDLGATVEEVSIPLH 321

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 301 QHAIPAYYVIAPAEASSNLSRFDGvrYGYrcdapqNLEDLY-----------KRSRAEGFGSEVKNRIMVGTYALSAgYY 369
Cdd:PRK07235 322 RLALAIWNPIATEGATAQMMLGNG--YGF------NWKGLYdtglldafgagWRERADDLSETVKLVMLLGQYGLER-YH 392

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 370 DAYYLQAQKIRRLIKNDFVSAFAEVDVILGPTTPNPAWKIGEKnDDPVSQYLEDIYTITANLA-----GLPGLSMPAGFV 444
Cdd:PRK07235 393 GRYYAKARNLARRLRAAYDEALRKYDLLVMPTTPMVATPLPAP-DASREEYVSRALEMIANTApfdvtGHPAMSVPCGLV 471

                        410       420       430
                 ....*....|....*....|....*....|.
gi 496673430 445 DGLPVGVQLLAPYFQEGRLLNVAHQYQQVSD 475
Cdd:PRK07235 472 DGLPVGLMLVGRHFDEATILRAAAAFEASGD 502
PRK07488 PRK07488
indoleacetamide hydrolase;
1-467 8.98e-86

indoleacetamide hydrolase;


Pssm-ID: 236030 [Multi-domain]  Cd Length: 472  Bit Score: 271.46  E-value: 8.98e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430   1 MLHQLTLAEIARALADKQFSAEELTRTLLGRIRQLdPQLNSFISITDDLAIAQAKAADERRANGENGALLGAPIAHKDLF 80
Cdd:PRK07488   7 DVASLSLTEAAAALRSGRLSCLELVEALLARAAAL-APLNAFTTVDAEGALAAARRIDAQRAAGAALLLAGVPIVIKDNI 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430  81 CTQGVRTSCGSKMLDNFVSPYDATVVEKLTAAGAVTLGKLNMDEFAMGSSNQSSHYGAVNNPWSLDRVPGGSSGGSAAAV 160
Cdd:PRK07488  86 NTAGMPTTAGTPALLGFVPATDAPVVQRLLDAGAVPLGKANMHELAFGITSNNGAFGAVRNPYDPARIAGGSSGGTAAAV 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 161 AARLLPAATGTDTGGSIRQPAALTNLTGIKPTYGRVSRWGMIAYASSLDQGGPLARTAEDCALMLGVMAGfdpkdstsve 240
Cdd:PRK07488 166 AARLAPAGLGTDTGGSVRIPAALCGVVGLRPTVGRYSGDGVVPISHTRDTVGPIARSVADLALLDAVITG---------- 235

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 241 qpvDDYLAALqKPLSGLRIGLPREYFGAGLDSRIADAVLAVVEELKTLGATVKDISLPNMQ---HAIPayYVIAPAEASS 317
Cdd:PRK07488 236 ---DAALPAP-VALAGLRLGVPAAPFWDGLDPDVAAVAEAALAKLAAAGVTFVELDLPGLHelnEAVG--FPIALYEALA 309

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 318 NLsrfdgVRYGYRCDAPQNLEDLykrsrAEGFGS-EVKN--RIMVGTYALSAgyyDAYYLQAQKIRRLIKNDFVSAFAE- 393
Cdd:PRK07488 310 DL-----RAYLRENGAGVSFEEL-----VARIASpDVRAifRDLLDPPQISE---DAYRAALDVGRPRLQAWYRQAFARh 376

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 394 -VDVILGPTTPNPAWKIGEKNDDPVSQYLEDIYTI------TANLAGLPGLSMPAGFV-DGLPVGVQLLAPYFQEGRLLN 465
Cdd:PRK07488 377 gLDAILFPTTPLTAPPIGDDDTVILNGAAVPTFARvirntdPASNAGLPGLSLPAGLTpHGLPVGLELDGPAGSDRRLLA 456


                 ..
gi 496673430 466 VA 467
Cdd:PRK07488 457 IG 458
PRK08137 PRK08137
amidase; Provisional
 2-484 3.42e-81

amidase; Provisional


Pssm-ID: 236161 [Multi-domain]  Cd Length: 497  Bit Score: 260.47  E-value: 3.42e-81
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430   2 LHQLTLAEIARALADKQFSAEELTRTLLGRIRQLD---PQLNSFISITDDlAIAQAKAAD-ERRANGENGALLGAPIAHK 77
Cdd:PRK08137   3 ALEERAGALQAAMPAGAAPASQLTRAYLQRIARIDrdgPRLNAVIELNPD-AEADAAALDaERKAGKVRGPLHGIPVLLK 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430  78 D-LFCTQGVRTSCGSKMLDNFVSPYDATVVEKLTAAGAVTLGKLNMDEFA-----MGSSNQSSHYGAVNNPWSLDRVPGG 151
Cdd:PRK08137  82 DnIDAADPMPTTAGSLALAGNRPTRDAFLVARLRDAGAVILGKANLSEWAnfrstRSSSGWSARGGLTRNPYALDRSPCG 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 152 SSGGSAAAVAARLLPAATGTDTGGSIRQPAALTNLTGIKPTYGRVSRWGMIAYASSLDQGGPLARTAEDCALMLGVMAGF 231
Cdd:PRK08137 162 SSSGSGAAVAAGLAAVAIGTETDGSITCPAAINGLVGLKPTVGLVSRDGIVPISHSQDTAGPMTRTVADAAAVLTAIAGG 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 232 DPKDSTSVEQPV--DDYLAALQK-PLSGLRIGLPREYFGAglDSRIADAVLAVVEELKTLGATVKDISLPN--------- 299
Cdd:PRK08137 242 DPADPATASAPApaVDYVAALDAdALRGARLGVARNYLGY--HPEVDAQFERALAELKAAGAVVIDVVDLDdgdwgeaek 319

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 300 ------MQHAIPAYyviapaeassnLSRFDGvrygyrcDAP-QNLEDLYKRSRA------EGFGSEVKNRIMVgtyalSA 366
Cdd:PRK08137 320 vvllheFKAGLNAY-----------LRSTAP-------HAPvRTLADLIAFNRAqharemPYFGQELFEQAQA-----AP 376

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 367 GYYDAYYLQAQ-KIRRLIKNDFVSAFAE---VDVILGPTTpNPAWKIGEKNDDpvsQYLEDIYTITAnLAGLPGLSMPAG 442
Cdd:PRK08137 377 GLDDPAYLDALaDAKRLAGPEGIDAALKehrLDALVAPTT-GPAWLIDLINGD---SFGGSSSTPAA-VAGYPHLTVPMG 451

                        490       500       510       520
                 ....*....|....*....|....*....|....*....|..
gi 496673430 443 FVDGLPVGVQLLAPYFQEGRLLNVAHQYQQVSDWhtRTPAGF 484
Cdd:PRK08137 452 QVQGLPVGLSFIGAAWSEARLLELGYAYEQATHA--RREPRF 491
PRK06169 PRK06169
putative amidase; Provisional
 4-483 7.90e-76

putative amidase; Provisional


Pssm-ID: 180437 [Multi-domain]  Cd Length: 466  Bit Score: 245.32  E-value: 7.90e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430   4 QLTLAEIARALADKQFSAEELTRTLLGRIRQLDPQLNSFISITDDLAIAQAKAADERRANGEN-GALLGAPIAHKDLFCT 82
Cdd:PRK06169   6 DLTAVELLAAYRRGELSPVEATQAVLDRIDRRDPAVNAFCLVDAEGALAAARASEERWRRGEPcGLLDGVPVSIKDIFLT 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430  83 QGVRTSCGSKMLDNfVSPY--DATVVEKLTAAGAVTLGKLNMDEFAMGSSNQSSHYGAVNNPWSLDRVPGGSSGGSAAAV 160
Cdd:PRK06169  86 RGWPTLRGSRAIDA-DGPWdvDAPAVARLREAGAVLLGKTTTPEFGWKGVTDSPLYGITRNPWDTRLTAGGSSGGAAAAV 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 161 AARLLPAATGTDTGGSIRQPAALTNLTGIKPTYGRVSRWGMIAYaSSLDQGGPLARTAEDCALMLGVMAGFDPKDSTSVE 240
Cdd:PRK06169 165 ALGMGPLSVGTDGGGSVRIPASFCGTFGFKPTFGRVPLYPASPF-GTLAHVGPMTRTVADAALLLDVIARPDARDWSALP 243

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 241 QPVDDYLAALQKPLSGLRIGLPREYFGAGLDSRIADAVLAVVEELKTLGATVKDISlPNMQHAIPAYYVIAPAEASSNLS 320
Cdd:PRK06169 244 PPTTSFLDALDRDVRGLRIAYSPTLGYVDVDPEVAALVAQAVQRLAALGARVEEVD-PGFSDPVEAFHVLWFAGAARLLR 322

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 321 RF-DGVRygyrcdapQNLEDLYKRSRAEGfgsevknrimvGTYALSAgYYDAYYLQAQKIRRLikndfvSAFAEV-DVIL 398
Cdd:PRK06169 323 ALpPGQR--------ALLDPGLRRIAERG-----------ATYSASD-YLDATAVRAALGARM------GAFHERyDLLL 376

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 399 GPTTPNPAWKIGEknDDPVSQYLEDI-----YTITANLAGLPGLSMPAGFV-DGLPVGVQLLAPYFQEGRLLNVAHQYQQ 472
Cdd:PRK06169 377 TPTLPIPAFEAGH--DVPPGSGLTDWtqwtpFTYPFNLTQQPAASVPCGFTaAGLPVGLQIVGPRHSDDLVLRVARAYEQ 454

                        490
                 ....*....|.
gi 496673430 473 VSDWHTRTPAG 483
Cdd:PRK06169 455 ALPWPHGAPAA 465
PRK07139 PRK07139
amidase; Provisional
 62-467 1.65e-71

amidase; Provisional


Pssm-ID: 235945 [Multi-domain]  Cd Length: 439  Bit Score: 233.40  E-value: 1.65e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430  62 ANGENGALLGAPIAHKDLFCTQGVRTSCGSKMLDNFVSPYDATVVEKLTAAGAVTLGKLNMDEFAMGSSNQSSHYGAVNN 141
Cdd:PRK07139  30 KNNKDGPLANCVFTIKDNFATSEGPTHASSKSLENFKPSYNATVVQKLINAGAKPVAKVHCDELGLGGTGLFSAFGLIKN 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 142 PWSLDRVpGGSSGGSAAAVAARLLPAATGTDTGGSIRQPAALTNLTGIKPTYGRVSRWGMIAYASSLDQGGPLARTAEDC 221
Cdd:PRK07139 110 PLDSSKL-VGGSSSGSAATFNKNISFAIGSDTGDSVRLPASFIGKVGFKPSYGAISRYGLFAYASSLDTVAYFTHNVNDA 188

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 222 ALMLGVMAGFDPKDSTSVEQPVDDylAALQKPLSGLRIGLPREyfgagLDSRIADAVLAVVEELKTLGATVKDISLP-NM 300
Cdd:PRK07139 189 IILSKVLFGKDENDLTSVDVKINN--VKKTKPKKVAYLDCFKE-----LEEYVAKKYKKLINILKSENIEVEKIKIDeKL 261

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 301 QHAI-PAYYVIAPAEASSNLSRFDGVRYGYRCDApQNLEDLYKRSRAEGFGSEVKNRIMVGTYALSAGYYDAYYLQAQKI 379
Cdd:PRK07139 262 LKAIkPVYKIISYSEASSNLANLNGIAFGNREKG-SSWEEIMINTRSEGFGKMVQKRLILGSYFLEEENQEKYFLKAKKV 340

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 380 RRLIKNDFVSAFAEVDVILGPTTPNPAWKIGEKNDDPvSQYLEDIYTItANLAGLPGLSMPAGFVDGLPVGVQLLAPYFQ 459
Cdd:PRK07139 341 RRVIKNYYESIHNKFDIVIYPAYADIAPDIDENENKS-DNYMDYILTI-SNLVGNPSLSIPLGKYNNLPFNLAIDSKIYD 418


                 ....*...
gi 496673430 460 EGRLLNVA 467
Cdd:PRK07139 419 DEKLLSYS 426
PRK06061 PRK06061
amidase; Provisional
 6-481 1.13e-70

amidase; Provisional


Pssm-ID: 235686 [Multi-domain]  Cd Length: 483  Bit Score: 232.67  E-value: 1.13e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430   6 TLAEIARALADKQFSAEELTRTLLGRIRQLDPQLNSFISITDDLAIAQAKAADERRANGENGALLGAPIAHKDLFCTQGV 85
Cdd:PRK06061  19 GLTDQAYQLASGAVTSVELVRRSLRRIEASQPTLNAFRVVRAEAALAEAAEADRRRAAGDRLPLLGVPIAVKDDVDVAGV 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430  86 RTSCGSkMLDNFVSPYDATVVEKLTAAGAVTLGKLNMDEFAMGSSNQSSHYGAVNNPWSLDRVPGGSSGGSAAAVAARLL 165
Cdd:PRK06061  99 PTAFGT-AGEVPPATADSEVVRRLRAAGAVIVGKTNTCELGQWPFTSGPAFGHTRNPWSRDHTPGGSSGGSAAAVAAGLV 177

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 166 PAATGTDTGGSIRQPAALTNLTGIKPTYGRVSRWGMIAYASSLDQGGPLARTAEDCALMLGVMAGFDPKDSTSveQPVDD 245
Cdd:PRK06061 178 TAAIGSDGAGSVRIPAAWTHLVGIKPQRGRISTWPLPEAFNGLTVNGPLARTVADAALLLDAASGNHPGDRHR--PPPVT 255

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 246 YLAALQKPLSGLRIGL----PREYFGAGLDSRIADAVLAVVEELKTLGATVKDislpnmqhAIPAYYVIApaeASSNLSR 321
Cdd:PRK06061 256 VSDAVGRAPGPLRIALstrfPFTGFPAKLHPEIRAAVRRVAEQLALLGHTVVP--------ADPDYGLRL---GLNFLPR 324

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 322 -FDGVR-YGYRCDAPQNLEdlyKRSRAE-GFGSEVKNRIMVGTYALSAGyydayylQAQKIRRLikndfvsaFAEVDVIL 398
Cdd:PRK06061 325 sTAGLRdWAERLGDPVLLD---PRTVSNaRMGRLLSQAILRLARAAEAA-------AQRRVGSI--------FDIVDVVL 386

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 399 GPTTPNPAWKIGEKNDdpVSQYLEDIYTITA-------NLAGLPGLSMPAGFV-DGLPVGVQLLAPYFQEGRLLNVAHQY 470
Cdd:PRK06061 387 APTTAQPPPRVGAFDR--LGGWATDRAMIAAcpytwpwNVLGWPSINVPAGFTsDGLPIGAQLMGPANSEPLLISLAAQL 464

                        490
                 ....*....|.
gi 496673430 471 QQVSDWHTRTP 481
Cdd:PRK06061 465 EAVSGWAERQP 475
PRK07486 PRK07486
amidase; Provisional
 5-481 7.39e-66

amidase; Provisional


Pssm-ID: 236028 [Multi-domain]  Cd Length: 484  Bit Score: 219.89  E-value: 7.39e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430   5 LTLAEIARALADKQFSAEELTRTLLGRIRQLDPQLNSFISITD-DLAIAQAKAADERRANGE-NGALLGAPIAHKDLFCT 82
Cdd:PRK07486  12 LSAHALSRAIRRRQVSCVEVMRAYLAHIERVNPAVNAIVALRDrDALLAEAAEKDAALARGEyRGWLHGMPQAPKDLAPT 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430  83 QGVRTSCGSKMLDNFVSPYDATVVEKLTAAGAVTLGKLNMDEFAMGSSNQSSHYGAVNNPWSLDRVPGGSSGGSAAAVAA 162
Cdd:PRK07486  92 KGIRTTLGSPIFADQVPQEDAIVVERMRAAGAIFIGKTNTPEFGLGSHTYNPVYGATRNPYDPSRSAGGSSGGAAAALAL 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 163 RLLPAATGTDTGGSIRQPAALTNLTGIKPTYGRVSRWGMI-AYASSLDQGGPLARTAEDCALMLGVMAGFDPKDSTSVEQ 241
Cdd:PRK07486 172 RMLPVADGSDMMGSLRNPAAFNNVYGFRPSQGRVPHGPGGdVFVQQLGTEGPMGRTVEDVALLLAVQAGYDPRDPLSLAE 251

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 242 PVDDYLAALQKPLSGLRIGLPREYFGAGLdsrIADAVLAVVEE----LKTLGATVkdislpnmQHAIPAYyviaPAEA-- 315
Cdd:PRK07486 252 DPARFAQPLEADLRGKRIAWLGDWGGYLP---MEAGVLELCEAalatLRELGCDV--------EAALPAF----PPERlw 316

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 316 -----SSNLSRFDGVRYGYRCDAPQNL---EDLYKRSRAEGF-GSEVknrimvgtYALSAGYYDAYylqaQKIRRLiknd 386
Cdd:PRK07486 317 rawltLRHFLVGGSLLALYRDPARRALlkpEAIWEIEGGLALtAAQV--------YEASVIRSAWY----QALLRL---- 380

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 387 fvsaFAEVDVILGPTT---PNPA---W--KIGEKNDDPVSQYLEDIytITANLAGLPGLSMPAGF-VDGLPVGVQLLAPY 457
Cdd:PRK07486 381 ----FERYDFLALPTAqvfPFDAewrWprAIAGRAMDTYHRWMEVV--VPATLAGLPAISVPVGFnAAGLPMGMQIIGPP 454

                        490       500
                 ....*....|....*....|....
gi 496673430 458 FQEGRLLNVAHQYQQVSDWHTRTP 481
Cdd:PRK07486 455 RADLAVLQLAHAYEQATDWVQRRP 478
PRK07042 PRK07042
amidase; Provisional
 2-482 1.44e-62

amidase; Provisional


Pssm-ID: 235915 [Multi-domain]  Cd Length: 464  Bit Score: 210.60  E-value: 1.44e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430   2 LHQLTLAEIARALADKQFSAEELTRTLLGRIRQLDPQLNSFISITDDLAIAQAKAADERRANGE-NGALLGAPIAHKDLF 80
Cdd:PRK07042   4 LHDLSAVELLAGYRARSLSPVEVTEAVLAHIARWEPHLNALYAFDPEAARAAARASTARWAKGEpLGPLDGVPVTIKENI 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430  81 CTQGVRTSCGSKMLDNFVSPYDATVVEKLTAAGAVTLGKLNMDEFAMGSSNQSSHYGAVNNPWSLDRVPGGSSGGSAAAV 160
Cdd:PRK07042  84 ATRGVPVPLGTAATDLPPAAADAPPAARLREAGAVILAKTTMPDYGMLSSGLSSFHGLTRNPWDLDQNPGGSSAGAGAAA 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 161 AARLLPAATGTDTGGSIRQPAALTNLTGIKPTYGRVS----RWGMIAyassldqgGPLARTAEDCALMLGVMAGFDPKDS 236
Cdd:PRK07042 164 AAGYGPLHLGTDIGGSVRLPAGWCGIVGLKPSLGRIPidppYTGRCA--------GPMTRTVDDAALLMSVLSRPDARDG 235

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 237 TSVEqPVDDYLAALQKPLSGLRIGLPREY-FGAGLDSRIADAVLAVVEELKTLGATVK---------------------- 293
Cdd:PRK07042 236 TSLP-PQDIDWSDLDIDVRGLRIGLMLDAgCGLAVDPEVRAAVEAAARRFEAAGAIVEpvppfltramldgldrfwrarl 314

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 294 --DIS-LPNMQHAIPAYYVIAPAEASSNLSRFDGVRygyrcdapqnledlykrsraeGFGsevknrimvgtyalsagyyd 370
Cdd:PRK07042 315 wsDLAaLPPERRAKVLPYIRRWAEGGADLSGVEAVR---------------------GFN-------------------- 353

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 371 ayylQAQKIRRLIkndfVSAFAEVDVILGPTTPNPAW--KIGEKNDDPvSQYLEDI-YTITANLAGLPGLSMPAGFV-DG 446
Cdd:PRK07042 354 ----QTFAMRAAA----ARLFAEFDYVLSPVAPVPAFpaEWASPTNDP-ARPFEHIaFTVPWNMSEQPAASINCGFTrDG 424

                        490       500       510
                 ....*....|....*....|....*....|....*.
gi 496673430 447 LPVGVQLLAPYFQEGRLLNVAHQYQQVSDWHTRTPA 482
Cdd:PRK07042 425 LPIGLQIVGPRFDDLGVLRLAKAFEGWRGPQRPWPE 460
PRK06828 PRK06828
amidase; Provisional
 3-481 8.94e-61

amidase; Provisional


Pssm-ID: 180715 [Multi-domain]  Cd Length: 491  Bit Score: 206.59  E-value: 8.94e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430   3 HQLTLAEIARALADKQFSAEELTRTLLGRIRQLD---PQLNSFISITDDlAIAQAKAAD-ERRANGENGALLGAPIAHKD 78
Cdd:PRK06828  11 KELTIHDIQTAMEDGKLTSKELVMYYLHRIAKYDqdgPKINSILEINPD-AIFIAEALDhERKIKGVRGPLHGIPVLLKD 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430  79 LFCTQG-VRTSCGSKMLDNFVSPYDATVVEKLTAAGAVTLGKLNMDEFAMGSSNQ-----SSHYGAVNNPWS---LDRVP 149
Cdd:PRK06828  90 NIETNDsMHTSAGTIALEQHISSEDAFLVTKLREAGAVILGKANMTELANFMSFEmwagySARGGQTINPYGtgeDDMFV 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 150 GGSSGGSAAAVAARLLPAATGTDTGGSIRQPAALTNLTGIKPTYGRVSRWGMIAYASSLDQGGPLARTAEDCALMLGVMA 229
Cdd:PRK06828 170 GGSSTGSAIAVAANFTVVSVGTETDGSILSPAVQNSVVGIKPTVGLISRRGIIPFTYSQDTAGPFARTVTDAAILLGSLT 249

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 230 GFDPKD---STSVEQPVDDYLAALQ-KPLSGLRIGL----PREYFGAGLDSRiaDAVLAVVEELKTLGAT-VKDISLPN- 299
Cdd:PRK06828 250 GVDEKDvvtHKSEGIAEHDYTKYLDaNGLNGAKIGVynnaPKEYYESGEYDE--KLFKETIEVLRSEGATvVEDIDIPSf 327

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 300 ------------MQHAIPAYYVIAPAeassnlsrfdgvryGYRCDAPQNLEDLYKR--SRAEGFGSE-VKNRIMVGTYAL 364
Cdd:PRK06828 328 hrewswgvllyeLKHSLDNYLSKLPS--------------TIPVHSISELMEFNENiaERALKYGQTkLERRKDFPNTLR 393

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 365 SAGYYDA-----YYLQAQKIrrliknDFVSAFAEVDVILGPTTpnpawkIGeknddpvsqylediYTITANlAGLPGLSM 439
Cdd:PRK06828 394 NPEYLNArlediYFSQEQGI------DFALEKYNLDAILFPSY------IG--------------STICAK-AGYPSIAI 446

                        490       500       510       520
                 ....*....|....*....|....*....|....*....|...
gi 496673430 440 PAGFVD-GLPVGVQLLAPYFQEGRLLNVAHQYQQVSDwHTRTP 481
Cdd:PRK06828 447 PAGYMEgGRPFGITLASTAFSEGTLIKLAYAFEQATK-HRKIP 488
PRK12470 PRK12470
amidase; Provisional
 8-481 6.48e-58

amidase; Provisional


Pssm-ID: 171524 [Multi-domain]  Cd Length: 462  Bit Score: 198.18  E-value: 6.48e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430   8 AEIARALADKQFSAEELTRTLLGRIRQLDPQLNSFISITDDLAIAQAKAADERRANGENGALLGAPIAHKDLFCTQGVRT 87
Cdd:PRK12470  12 AAQARMLADGELTAPMLLEVYLQRIERLDSHLRAYRVVLFDRARAEAEAAQQRLDAGERLPLLGVPIAIKDDVDVAGEVT 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430  88 SCGSKMLDNFVSPyDATVVEKLTAAGAVTLGKLNMDEFAMGSSNQSSHYGAVNNPWSLDRVPGGSSGGSAAAVAARLLPA 167
Cdd:PRK12470  92 TYGSAGHGPAATS-DAEVVRRLRAAGAVIIGKTNVPELMIMPFTESLAFGATRNPWDPNRTPGGSSGGSAAAVAAGLAPV 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 168 ATGTDTGGSIRQPAALTNLTGIKPTYGRVSRWGMIAYASSLDQGGPLARTAEDCALMLGVMagfdpkdsTSVEQPVDDYL 247
Cdd:PRK12470 171 ALGSDGGGSIRIPSTWCGLFGLKPQRDRISLEPHDGAWQGLSVNGPIARSVMDAALLLDAT--------TTVPGPEGEFV 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 248 AALQKPLSGLRIGLPREyFGAGLDSRIADAVLAVVEE----LKTLGATVKDISlpnmqhaiPAYyviaPAEASSN-LSRF 322
Cdd:PRK12470 243 AAAAREPGRLRIALSTR-VPTPLPVRCGKQELAAVHQagalLRDLGHDVVVRD--------PDY----PAATYANyLPRF 309

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 323 DGvryGYRCDAPQ--NLEDLYKRSRAEG-FGSEVKNRIMvgtyalsAGYYDAYYLQAQKIRRLikndfvsaFAEVDVILG 399
Cdd:PRK12470 310 FR---GISDDADAqaHPDRLEARTRAIArLGSFFSDRRM-------AALRAAEVVLSARIQSI--------FDDVDVVVT 371

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 400 PTTPNPAWKIGE-KNDDPVSQYLEDI----YTITANLAGLPGLSMPAGF-VDGLPVGVQLLAPYFQEGRLLNVAHQYQQV 473
Cdd:PRK12470 372 PGTATGPSRIGAyQRRGAVSTLLLVVqrvpYFQVWNLTGQPAAVVPWDFdGDGLPMSVQLVGRPYDEATLLALAAQIESA 451


                 ....*...
gi 496673430 474 SDWHTRTP 481
Cdd:PRK12470 452 RPWAHRRP 459
PRK06170 PRK06170
amidase; Provisional
 5-460 2.80e-57

amidase; Provisional


Pssm-ID: 235723 [Multi-domain]  Cd Length: 490  Bit Score: 197.18  E-value: 2.80e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430   5 LTLAEIARALADKQFSAEELTRTLLGRIRQLDPQLNSFISITDDLAIAQAKAADERRANGENGALLGAPIAHKDLFCTQG 84
Cdd:PRK06170  12 LPATELAAALAAGEVSSVELTDLAIARIERHDGKINAIVVRDFDRARAAARAADAARARGERGPLLGIPVTVKESFNVAG 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430  85 VRTSCGSKMLDNFVSPYDATVVEKLTAAGAVTLGKLNMdefAMGSSN-QSSH--YGAVNNPWSLDRVPGGSSGGSAAAVA 161
Cdd:PRK06170  92 LPTTWGFPDLRDYVPAEDAVAVARLKAAGAVILGKTNV---PLGLQDwQSYNeiYGTTNNPWDLARTPGGSSGGSAAALA 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 162 ARLLPAATGTDTGGSIRQPAALTNLTGIKPTYGRVSRWGMIAYASSLDQG-------GPLARTAEDCALMLGVMAGFDPK 234
Cdd:PRK06170 169 AGFGALSIGSDIGGSLRVPAHYCGVYAHKPTLGLVPLRGHIPPPAPALPGqadlavaGPMARSARDLALLLDVMAGPDPL 248

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 235 D---STSVEQPvddylAALQKPLSGLRIGLPREYFGAGLDSRIADAVLAVVEELKTLGATVKDIS--LPNMQHAIPAYYV 309
Cdd:PRK06170 249 DggvAYRLALP-----PARHGRLKDFRVLVLDEHPLLPTDAAVRAAIERLAAALADAGARVVRHSplLPDLAESARLYMR 323

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 310 IapaeassnLSRFDGVRYgyrcdapqnLEDLYKRSRAEGFGSEVKNRIMVGTYALSAGYYDAYYLQAQKIRRLIKNDFVS 389
Cdd:PRK06170 324 L--------LFAASAARF---------PPDAYADAQARAAGLSADDRSLAAERLRGAVLSHRDWLFADAAREELRAAWRR 386

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 390 AFAEVDVILGPTTPNPAWKIGEKND--------DPVSQYLED--IYTITANLAGLPGLSMPAGFV-DGLPVGVQLLAPYF 458
Cdd:PRK06170 387 FFAEFDVVLCPVTPTPAFPHDHAPDplerridiDGVSYPYWDqlVWAGLATLPGLPATAIPIGLSaTGLPVGVQIVGPAL 466


                 ..
gi 496673430 459 QE 460
Cdd:PRK06170 467 ED 468
PRK07056 PRK07056
amidase; Provisional
 6-473 1.37e-54

amidase; Provisional


Pssm-ID: 235921 [Multi-domain]  Cd Length: 454  Bit Score: 189.38  E-value: 1.37e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430   6 TLAEIARALADKQFSAEELTRTLLGRIRQLDPQLNS-FISITDDLAIAQAKAADE-RRANGENGALLGAPIAHKDLFCTQ 83
Cdd:PRK07056   7 TLAALAADLAAGRTTSRALVEAALARIADPAGEGARvFTHVDADAARAAADAADAlRAAGAAPSPLAGIPVSVKDLFDVA 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430  84 GVRTSCGSKML-DNFVSPYDATVVEKLTAAGAVTLGKLNMDEFAMGSSNQSSHYGAVNNPWSLD----RVPGGSSGGSAA 158
Cdd:PRK07056  87 GQVTRAGSRVLaDAPPAAADAPAVARLRRAGAVLIGRTNMTEFAFSGLGLNPHYGTPRNPWRRDvgdgRIPGGSSSGAAV 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 159 AVAARLLPAATGTDTGGSIRQPAALTNLTGIKPTYGRVSRWGMIAYASSLDQGGPLARTAEDCALMLGVMAGFDPkdsts 238
Cdd:PRK07056 167 SVADGMAAAALGTDTGGSIRIPAALCGLTGFKPTARRVPLQGAVPLSTTLDSIGPLARSVACCALVDAVLAGEEP----- 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 239 veqpvddyLAALQKPLSGLRIGLPREYFGAGLDSRIADAVLAVVEELKTLGATVKDISLPNMQH--AIPAYYVIAPAEAs 316
Cdd:PRK07056 242 --------VVPAARPLEGLRLAVPTTVVLDGLDATVAAAFERALKRLSAAGAIIEEIAFPELAElaEINAKGGFSAAES- 312

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 317 snlsrfdgvrYGYRCDAPQNLEDLYKRsraegfgsEVKNRIMVGTyALSAgyydAYYLQAQKIRRLIKNDFVSAFAEVDV 396
Cdd:PRK07056 313 ----------YAWHRPLLARHRDQYDP--------RVAARILRGE-PMSA----ADYIDLLAARAAWIARAAARLARFDA 369

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 397 ILGPTTPNPAWKIGEKNDDpvsqylEDIYTITANLA--------GLPG--LSMPAGFVDGLPVGVQLLAPYFQEGRLLNV 466
Cdd:PRK07056 370 LVMPTVPIVPPRIADLEAD------DAAFFRTNALLlrnpslinFLDGcaLSLPCHAPGEAPVGLMLAGAPGRDDRLLAI 443


                 ....*..
gi 496673430 467 AHQYQQV 473
Cdd:PRK07056 444 ALAVEAV 450
PRK07487 PRK07487
amidase; Provisional
 2-464 1.12e-52

amidase; Provisional


Pssm-ID: 236029 [Multi-domain]  Cd Length: 469  Bit Score: 184.40  E-value: 1.12e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430   2 LHQLTLAEIARALADKQFSAEELTRTLLGRIRQLDPQLNSFISITDDLAIAQAKAADERRANGEN-GALLGAPIAHKDLF 80
Cdd:PRK07487   5 LWRLSAAELAAAVRSRDVSAREAAEAALARLDAVNPAINAVVDHRPEEALAQADAVDAARARGDDpGPLAGVPVTVKVNV 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430  81 CTQGVRTSCGSKMLDNFVSPYDATVVEKLTAAGAVTLGKLNMDEFAMG--SSNQSshYGAVNNPWSLDRVPGGSSGGSAA 158
Cdd:PRK07487  85 DQAGFATTNGVRLQKDLIAPADSPVVDNLRKAGAVIIGRTNTPAFSYRwfTDNPL--HGRTLNPWDPSLTPGGSSGGAAA 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 159 AVAARLLPAATGTDTGGSIRQPAALTNLTGIKPTYGRVSRWgmiaYASSLDQG---------GPLARTAEDCALMLGVMA 229
Cdd:PRK07487 163 AVAAGIGAIAHGTDIGGSIRYPAYACGVHGLRPTLGRVPAY----NASSPERPigaqlmsvqGPLARTVADLRLALAAMA 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 230 GFDPKDSTSVEqpvddylAALQKPLSGLRIGLPREYFGAGLDSRIADAVLAVVEELKTLGATVKDIS-LPNMQHAIPAYY 308
Cdd:PRK07487 239 APDPRDPWWVP-------APLEGPPRPKRVALCVRPDGLDVDPEVEAALRDAARRLEDAGWTVEEVDdTPPLREAAELQE 311

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 309 VIAPAEASSNLsrfdgvrygyrcdapqnledlykRSRAEGFGSEVKNRIMVGTYALSAGYYDAYYLQAQKIRRLIKNDFV 388
Cdd:PRK07487 312 RLWLGDGYEAL-----------------------LAAAEAEGDPGALAALRGQRAKARPLDLAGYMNALARRATLTRQWQ 368

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 496673430 389 SAFAEVDVILGPTTPNP--AWKIGEKNDDPVSQYLE-DIYTITANLAGLPGLSMPAGFVDGLPVGVQLLAPYFQEGRLL 464
Cdd:PRK07487 369 LFFEDYPLLLMPVSAELpfPDDLDRQGAEGFRRVWEaQLPQIALPFMGLPGLSVPTGLVGGVPVGVQLVAGRFREDLCL 447
PRK08186 PRK08186
allophanate hydrolase; Provisional
 5-476 2.71e-51

allophanate hydrolase; Provisional


Pssm-ID: 236177 [Multi-domain]  Cd Length: 600  Bit Score: 183.50  E-value: 2.71e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430   5 LTLAEIARALADKQFSAEELTRTLLGRIRQlDPQLNSFISITD-DLAIAQAKAADERRAngENGALLGAPIAHKDLFCTQ 83
Cdd:PRK08186   7 LTLASLRAAYRAGTLTPRAVVAALYARIAA-VDDPEVWIHLRPeADLLAQAAALEARDP--AALPLYGVPFAVKDNIDVA 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430  84 GVRTSCGSKMLdNFVSPYDATVVEKLTAAGAVTLGKLNMDEFAMGSSNQSSHYGAVNNPWSLDRVPGGSSGGSAAAVAAR 163
Cdd:PRK08186  84 GLPTTAACPAF-AYTPERDATVVARLRAAGAIVIGKTNLDQFATGLVGTRSPYGAVRNAFDPEYVSGGSSSGSAVAVALG 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 164 LLPAATGTDTGGSIRQPAALTNLTGIKPTYGRVSRWGMIAYASSLDQGGPLARTAEDCALMLGVMAGFDPKDSTSVEQPV 243
Cdd:PRK08186 163 LVSFALGTDTAGSGRVPAAFNNIVGLKPTLGLLSTRGVVPACRTLDCVSVFALTVDDADAVLAVMAGFDPADPYSRANPA 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 244 DDYLAALQKPlsglRIGLPR----EYFGaglDSRIADAVLAVVEELKTLGATVKDISlpnmqhaipayyvIAP-AEASSN 318
Cdd:PRK08186 243 DAPAALPAGP----RVGVPRaaqlEFFG---DAEAEAAFAAALARLEALGAELVEID-------------FSPfLEAARL 302

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 319 LsrFDGVRYGYRCDAPQNLEDlykrSRAEGFGSEVKNrIMVGTYALSA--GYYDAYYLQAqkIRRLIKndfvSAFAEVDV 396
Cdd:PRK08186 303 L--YEGPWVAERYAAVGEFLE----AHPDAVDPVVRG-IIAGAAAFSAadAFRALYRLAE--LRRAAE----AVLAGIDA 369

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 397 ILGPTTPNPaWKIGEKNDDPV---SQYleDIYTITANLAGLPGLSMPAGFV-DGLPVGVQLLAPYFQEGRLLNVAHQYQQ 472
Cdd:PRK08186 370 LLVPTAPTH-PTIAEVAADPIglnSRL--GTYTNFVNLLDLCALAVPAGFRaDGLPFGVTLIAPAFADQALADLAARLQA 446


                 ....
gi 496673430 473 VSDW 476
Cdd:PRK08186 447 ALAL 450
PRK06102 PRK06102
amidase;
1-467 3.39e-51

amidase;


Pssm-ID: 235698 [Multi-domain]  Cd Length: 452  Bit Score: 180.23  E-value: 3.39e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430   1 MLHQLTLAEIARALADKQFSAEELTRTLLGRIRQLDPQlNSFISITDDLAIAQAKAADER-RANGENGALLGAPIAHKDL 79
Cdd:PRK06102   2 STGAKSAAQLAVLIQSGALDPVQVAEQALDAIASYADQ-AVFISLTEERAMREAEASSARwRAGRSLGLLDGIPIAWKDL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430  80 FCTQGVRTSCGSKMLDNfVSP--YDATVVEKLTAAGAVTLGKLNMDEFAMGSSNQSSHYGAVNNPWSLD--RVPGGSSGG 155
Cdd:PRK06102  81 FDVAGSVTTAGSVVLAN-AAPasRDAAVVALLARAGMVSIGRTNMSEFAFSGLGLNPHYGTPVNPRSTDvpRIPGGSSSG 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 156 SAAAVAARLLPAATGTDTGGSIRQPAALTNLTGIKPTYGRVSRWGMIAYASSLDQGGPLARTAEDCALMLGVMAGFDPKD 235
Cdd:PRK06102 160 SAVAVAAGLVPVAMGTDTGGSVRIPAAFNGLVGYKATRGRYSMDGVFPLAKSLDSLGPLCRSVRDAVWIDAAMRGLTAPD 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 236 STsveqpvddylaalQKPLSGLRIGLPREYFGAGLDSRIADAVLAVVEELKTLGATVKDISLPNMQHA---IPAYYVIAP 312
Cdd:PRK06102 240 VV-------------RRPLAGLRLVVPETVVFDDAEPGVRAAFEAAVERLQAAGALVERQAFPAFQEIldlIARHGWLVT 306

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 313 AEA-SSNLSRFDGVrygyrcDAPQNLEDLYKRSRAegfGSEvknrimvgtyaLSAGYYDAYYLQAqkiRRLIKnDFVSAF 391
Cdd:PRK06102 307 AEAfALHQERLDGP------DAARMDPRVVKRTRL---GRK-----------ITASDYIALLEAR---ERLIA-QVTREL 362

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 392 AEvDVILGPTTPNPAWKIGEKNDDpvsqylEDIYTITaNLAGL-----------PGLSMPAGFVD-GLPVGVQLLAPYFQ 459
Cdd:PRK06102 363 GG-ALLATPTVAHVAPPLAPLEAD------DDLFFAT-NLKTLrntmpgnfldmCGVSLPCGTGAaGMPVGLLLSAPAGR 434


                 ....*...
gi 496673430 460 EGRLLNVA 467
Cdd:PRK06102 435 DERLLRAA 442
PRK06707 PRK06707
amidase; Provisional
 6-474 2.66e-46

amidase; Provisional


Pssm-ID: 235855 [Multi-domain]  Cd Length: 536  Bit Score: 168.93  E-value: 2.66e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430   6 TLAEIARALADKQFSAEELTRTLLGRIRQLDPQLNSFISITD--DLAIAQAKAADERRANGENGALLGAPIAHKDLFCTQ 83
Cdd:PRK06707  72 TVDELQKMIDDGKLSYEELTSIYLFRIQEHDQNGITLNSVTEinPNAMEEARKLDQERSRNKKSNLYGIPVVVKDNVQTA 151

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430  84 GV-RTSCGSKMLDNFVSPYDATVVEKLTAAGAVTLGKLNMDEFA-----MGSSNQSSHYGAVNNPWS-LDRVPGGSSGGS 156
Cdd:PRK06707 152 KVmPTSAGTYVLKDWIADQDATIVKQLKEEGAFVLGKANMSEWAnylsfTMPSGYSGKKGQNLNPYGpIKFDTSGSSSGS 231

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 157 AAAVAARLLPAATGTDTGGSIRQPAALTNLTGIKPTYGRVSRWGMIAYASSLDQGGPLARTAEDCALMLGVMAGFDPKDS 236
Cdd:PRK06707 232 ATVVAADFAPLAVGTETTGSIVAPAAQQSVVGLRPSLGMVSRTGIIPLAETLDTAGPMARTVKDAATLFNAMIGYDEKDV 311

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 237 TSVEQP---VDDYLAALQKP-LSGLRIGLpreyfgAGLDSRIADAVLAVVEELKTL----GATVKDISLPNMQhAIPAYY 308
Cdd:PRK06707 312 MTEKVKdkeRIDYTKDLSIDgLKGKKIGL------LFSVDQQDENRKAVAEKIRKDlqdaGAILTDYIQLNNG-GVDNLQ 384

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 309 VIApAEASSNLSRFDGVRYgyrcDAP-QNLEDLYKRSRaegfgSEVKNRIMVGTYALSAGYYDAYYLQ--AQKIRRLIKN 385
Cdd:PRK06707 385 TLE-YEFKHNVNDYFSQQK----NVPvKSLEEIIAFNK-----KDSKRRIKYGQTLIEASEKSAITKDefEKVVQTSQEN 454

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 386 dfvsAFAEVDVILgpttpnpawkiGEKNDDPVSQYLEDIYTITAnLAGLPGLSMPAGF-VDGLPVGVQLLAPYFQEGRLL 464
Cdd:PRK06707 455 ----AKKELDRYL-----------VEKGLDALVMINNEEVLLSA-VAGYPELAVPAGYdNNGEPVGAVFVGKQFGEKELF 518

                        490
                 ....*....|
gi 496673430 465 NVAHQYQQVS 474
Cdd:PRK06707 519 NIGYAYEQQS 528
PRK05962 PRK05962
amidase; Validated
 42-467 1.90e-45

amidase; Validated


Pssm-ID: 168315 [Multi-domain]  Cd Length: 424  Bit Score: 164.18  E-value: 1.90e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430  42 FISITDDLAIAQAKAADERRANGEN-GALLGAPIAHKDLFCTQGVRTSCGSKML-DNFVSPYDATVVEKLTAAGAVTLGK 119
Cdd:PRK05962  18 FSKLYAERARAEADAADARRRAGRSlGPLDGRIVSIKDLFDVAGEPTLAGSVIRrDAPPAGADALIVQRLRNAGAVIIGK 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 120 LNMDEFAMGSSNQSSHYGAVNNPWSLDRVPGGSSGGSAAAVAARLLPAATGTDTGGSIRQPAALTNLTGIKPTYGRVSRW 199
Cdd:PRK05962  98 THMTEFAFTPVGLNPHYGEPGNAIDPARIPGGSSSGAAVSVAEGTSEIAIGSDTGGSVRIPAALNGLVGFKPTARRIPLE 177

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 200 GMIAYASSLDQGGPLARTAEDCALMLGVMAGfdpkdstsvEQPVDdyLAALqkPLSGLRIGLPREYFGAGLDSRIADAVL 279
Cdd:PRK05962 178 GAFPLSPSLDSIGPLARTVADCAAADAVMAG---------EKPIP--LEVL--PVAGLRIGLPKGYLLADMEPDVAAAFE 244

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 280 AVVEELKTLGATVKDISLPNMQHAipayyvIAPAEASSNLSRFDGVRygyrcdapqnLEDLYKRSRAEGFGSEVKNRIMV 359
Cdd:PRK05962 245 ASLAALEKAGARIADLAIDDLIAR------LAEATRIGSIAGIEASH----------IHADWLADLDANVDIRVKRPLSR 308

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 360 GTYALSAGYYDAYYLQAQKIRRLikNDFVSAFaevDVILGPTTPNPAWKIGE-KNDDPVSQYLEDIY---TITANLAGLP 435
Cdd:PRK05962 309 RIKVPLEAYHRLMRTRAALARAM--DERLAGF---DMFALPATPIVAPTIASvSEDEEEYDRVENLLlrnTQVANQFDLC 383

                        410       420       430
                 ....*....|....*....|....*....|...
gi 496673430 436 GLSMP-AGFvdGLPVGVQLLAPYFQEGRLLNVA 467
Cdd:PRK05962 384 SITLPmPGM--ALPAGLMLTARNGSDRRLLAAA 414
PRK08310 PRK08310
amidase; Provisional
 58-468 1.30e-37

amidase; Provisional


Pssm-ID: 181375 [Multi-domain]  Cd Length: 395  Bit Score: 142.04  E-value: 1.30e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430  58 DERRANGENGALLGAPIAHKDLFCTQGVRTSCGS--KMLDNFVSPYDATVVEKLTAAGAVTLGKLNMDEFAMGSSNQSSH 135
Cdd:PRK08310  15 DKPLPHAASGPLAGLRFAVKDVFDVAGYVTGCGNpdWLAESPVATRTAPAVEKLLAAGARFVGKTQTDELAFSLNGQNAH 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 136 YGAVNNPWSLDRVPGGSSGGSAAAVAARLLPAATGTDTGGSIRQPAALTNLTGIKPTYGRVSRWGMIAYASSLDQGGPLA 215
Cdd:PRK08310  95 YGTPVNPAAPDRVPGGSSSGSAAAVAGGLADFALGTDTGGSVRAPASFCGLYGLRPTHGRISLEGVMPLAPSFDTVGWFA 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 216 RTAEDCALMLGVMAGFDPKDSTSVEqpvddylaalqkplsglRIGLPREYFGAgLDSRIADAVLAVVEELKTLGATVKDI 295
Cdd:PRK08310 175 RDIALLERVGEVLLGDDAQEFPLTQ-----------------RLLIPVDLFAL-LDPAVRAALEAALARLRPHLGPAKPA 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 296 SLPNMQhaIPAYY----VIAPAEASSnlsrfdgvRYGYRCDApqnledlYKRSraegFGSEVKNRimvgtYALSAGYYDA 371
Cdd:PRK08310 237 SVPPLS--LDEWYeafrVLQAAEAWE--------THGAWISS-------GNPQ----LGPGVADR-----FAAGAEVTAD 290

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 372 YYLQAQKIRRLIKNDFVSAFAEVDVILGPTTPNPAWKIGEKnddpvSQYLEDI------YTITANLAGLPGLSMPAGFVD 445
Cdd:PRK08310 291 QVEAARARRAAFARELAALLGPDAVLLLPTVPGAAPLRGAP-----FEALEAYreralrLLCIAGLAGLPQISLPLASVD 365

                        410       420
                 ....*....|....*....|...
gi 496673430 446 GLPVGVQLLAPYFQEGRLLNVAH 468
Cdd:PRK08310 366 GAPFGLSLIGPRGSDRSLLALAQ 388
PRK11910 PRK11910
amidase; Provisional
 7-474 1.06e-34

amidase; Provisional


Pssm-ID: 183377 [Multi-domain]  Cd Length: 615  Bit Score: 137.08  E-value: 1.06e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430   7 LAEIARALADKQFSAEELTRTLLGRIRQLDPQ---LNSFISITDDLaIAQAKAADERRANGENgALLGAPIAHKDLFCTQ 83
Cdd:PRK11910 167 VTKLQQLIATKQLSYKELAGIYLNRIKKYDQNglnLNAITEINPTI-IAEAEQLDKENTTNKS-ALYGMPVLLKDNIGTK 244

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430  84 GVRTSCGSKMLDNFVSPYDATVVEKLTAAGAVTLGKLNMDEFAMGSSNQ-----SSHYGAVNNPWSLDRVPGGSSGGSAA 158
Cdd:PRK11910 245 ELPTSAGTVALKDWVIGKDATIVENLKANGALILGKTNMSEWAAGMDEDlpngySGKKGQSKNPYSSNLDPSGSSSGSAT 324

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 159 AVAARLLPAATGTDTGGSIRQPAALTNLTGIKPTYGRVSRWGMIAYASSLDQGGPLARTAEDCALMLGVMAgfdpkDSTS 238
Cdd:PRK11910 325 AATSDFAAIAIGTETNGSIITPASAQSAVGYKPSQGLVNNKGIIPLSSRFDTPGPLTRTVNDAYLTTNALT-----NTTS 399

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 239 veqpvddylaalQKPLS-----GLRIGLPreyfgAGLDSRIADAVLAVVE-ELKTLGATV-KDISLPNMQHAIPAYYVIA 311
Cdd:PRK11910 400 ------------NPPLStdalkGKRIGLL-----ADGESNEETAVIKKIKlDLQKAGATIiEGIAVGEFEQKDTDYASLL 462

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 312 PAEASSNLSRFDGVRYgyrcdAPQN-LEDLYKrsraegFGSEVKNRIM-VGTYALSAGYYDAyyLQAQKIRRLIKNDFVS 389
Cdd:PRK11910 463 NADFKHDLNQFLQVNH-----SPMStLESIIQ------FNQTNPTRNMkYGQSELVKSQQST--ITKQQADNLASNLIQS 529

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 390 AFAEVDVILGpttpnpawkiGEKNDDPVSQYLEDIYTITANLAGLPGLSMPAGFVD--GLPVGVQLLAPYFQEGRLLNVA 467
Cdd:PRK11910 530 SQNELDSVLQ----------KDKLDAVVTIGMGGSVMFLAPIAGNPELTIPAGYDEesNQPISLTFITARNSDKILLNMG 599


                 ....*..
gi 496673430 468 HQYQQVS 474
Cdd:PRK11910 600 YAYEQQS 606
PRK06529 PRK06529
amidase; Provisional
 9-472 2.54e-34

amidase; Provisional


Pssm-ID: 180608 [Multi-domain]  Cd Length: 482  Bit Score: 134.56  E-value: 2.54e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430   9 EIARALADKQFSAEELTRTLLGRIRQLDPQLNSFISITDDLAIAQAKAADErrangENGALLGAPIAHKDLFCTQ-GVRT 87
Cdd:PRK06529   8 AMAQAVQQGQVTPLELVTQAIYKAKKLNPTLNAIVSERYEEALEEAKQRDF-----SGKPFAGVPIFLKDLGQELkGQLS 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430  88 SCGSKMLDNFVSPYDATVVEKLTAAGAVTLGKLNMDEFAMGSSNQSSHYGAVNNPWSLDRVPGGSSGGSAAAVAARLLPA 167
Cdd:PRK06529  83 TSGSRLFKNYQATKTDLYVKRLEDLGFIILGRSNTPEFGFKNISDSSLHGPVNLPFDNSRNAGGSSGGAAALVSSGIVAL 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 168 ATGTDTGGSIRQPAALTNLTGIKPTYGRVSRwGMIAYASSldQGG----PLARTAEDCALMLGVMagfdpkDSTSVEQPV 243
Cdd:PRK06529 163 AAASDGGGSIRIPASFNGLIGLKPSRGRIPV-GPGSYRGW--QGAsvhfALTKSVRDTRRLLYYL------QMYQMESPF 233

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 244 -------DDYLAALQKPlsgLRIGLpreYFGAGLDSRIADAVLAVVEE----LKTLGATVKDIS-LP-NMQHAIPAYYVI 310
Cdd:PRK06529 234 platlskESLFQSLQRP---LKIAF---YQRSPDGSPVSLDAAKALKQavtfLREQGHEVVELEeFPlDMTEVMRSYYIM 307

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 311 APAEASsnlSRFDGVrygyrcdapqnledlykrsrAEGFGSEV-KNRIMVGTYALsagyydayYLQAQKI------RRLI 383
Cdd:PRK06529 308 NSVETA---AMFDDI--------------------EDALGRPMtKDDMETMTWAI--------YQSGQDIpakrysQVLQ 356

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 384 KNDFVSA----FAE-VDVILGPTTPNPAWKIGEKNDDP-------------VSQYLEDI------------YTITANLAG 433
Cdd:PRK06529 357 KWDTYSAtmasFHEtYDLLLTFTTNTPAPKHGQLDPDSklmanlaqaeifsSEEQQNLVetmfekslaitpYTALANLTG 436

                        490       500       510       520
                 ....*....|....*....|....*....|....*....|
gi 496673430 434 LPGLSMPAGFV-DGLPVGVQLLAPYFQEGRLLNVAHQYQQ 472
Cdd:PRK06529 437 QPAISLPTYETkEGLPMGVQLIAAKGREDLLLGIAEQFEA 476
PRK07869 PRK07869
amidase; Provisional
 9-476 4.01e-32

amidase; Provisional


Pssm-ID: 181154 [Multi-domain]  Cd Length: 468  Bit Score: 128.18  E-value: 4.01e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430   9 EIARALADKQFSAEELTRTLLGRIRQLDPQLNSFISITDDLAIAQAKAADerranGENGALLGAPIAHKDLFCTQGVRTS 88
Cdd:PRK07869  19 GLAEAIRAGRVSAAEVVEAAIARAEAVNPALNALAYAAFDRARDRAARPG-----SQGGFFSGVPTFIKDNVDVAGLPTM 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430  89 CGSKMLDNFVSPYDATVVEKLTAAGAVTLGKLNMDEFAMGSSNQSSHYGAVNNPWSLDRVPGGSSGGSAAAVAARLLPAA 168
Cdd:PRK07869  94 HGSDAWTPRPAKADSDFARQFLATGLISLGKTQLPEFGFSASTEHPRLGPVRNPWNTDYSAGASSGGSAALVAAGVVPIA 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 169 TGTDTGGSIRQPAALTNLTGIKPTYGRVSrwgMIAYASSLDQG----GPLARTAEDCALMLGVMagfdpkdstsvEQpvd 244
Cdd:PRK07869 174 HANDGGGSIRIPAACCGLVGLKPSRGRLP---LDPELRRLPVNivanGVLTRTVRDTAAFYREA-----------ER--- 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 245 dYLAALQKPLSG---------LRIGL-PREYFGAGLDSRIADAVLAVVEELKTLGATVKDISLPnmqhaIPAYYVIAPAE 314
Cdd:PRK07869 237 -YYRNPKLPPIGdvtgpgkqrLRIAVvTDSVTGREADPEVREAVLATARLLEELGHRVEPVDLP-----VPASFVDDFLL 310

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 315 ASSNLSrFDGVRYGYRCDAPQnledlYKRSRAEGFgsevknrimvgTYALSAGYYDAYYLQAQKIRRLIKNDFVSA--FA 392
Cdd:PRK07869 311 YWGFLA-FALVRGGRRTFGPS-----FDRTRLDNL-----------TLGLARHARRNLHRLPLAIARLRRLRRVYArfFG 373

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 393 EVDVILGPTTPNPAWKIGEKN-DDPVSQYLEDI-----YTITANLAGLPGLSMPAGFV-DGLPVGVQLLAPYFQEGRLLN 465
Cdd:PRK07869 374 TYDVVLTPTLAHTTPEIGYLDpTQDFDTVLDRLisyvaFTPLQNATGEPAISLPLGQSsDGLPVGMMFSADVGDEATLLE 453

                        490
                 ....*....|.
gi 496673430 466 VAHQYQQVSDW 476
Cdd:PRK07869 454 LAYELEEAQPW 464
PLN02722 PLN02722
indole-3-acetamide amidohydrolase
 69-466 1.92e-24

indole-3-acetamide amidohydrolase


Pssm-ID: 166363  Cd Length: 422  Bit Score: 105.36  E-value: 1.92e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430  69 LLGAPIAHKDLFCTQGVRTSCGSKMLDNFVSPYDAT--VVEKLTAAGAVTLGKLNMDEFAMGSSNQSSHYGAVNNPWSLD 146
Cdd:PLN02722  27 LHGLTFAVKDIFDVEGYVTGFGNPDWARTHSAATSTapAVLAVLRGGATCVGKTIMDEMAYSINGENAHYGTPTNPIAPD 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 147 RVPGGSSGGSAAAVAARLLPAATGTDTGGSIRQPAALTNLTGIKPTYGRVSRWGMIAYASSLDQGGPLARTAEDCALMLG 226
Cdd:PLN02722 107 RVPGGSSSGSAVAVGAKLVDFSLGTDTGGSVRVPASYCGIFGFRPSHGAVSTVGVIPMAQSFDTVGWFARDPVILKRVGH 186

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 227 VMAGFDPKDSTSVEQPV--DDYLAALQKP---LSGLRIGLPREYFGAGldsriaDAVLAVVeelktLGATVKDiSLPNMQ 301
Cdd:PLN02722 187 VLLQQPDVNPIKPSQIIiaEDCFQLSSIPhdrLVQVLVKSVEKLFGGG------DIVKHVN-----LGDYVED-KVPSLK 254

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 302 HAIPA-----YYVIAPAEASSNLSRFDGvRYGYRCDAPQnledlYKRSRAEGFGSEVKNRImvgtyalsagyYDAYYLQA 376
Cdd:PLN02722 255 HFMSKeikeqEYNIPSLAALSSAMRLLQ-RYEFKINHGE-----WITAVKPEFGPGISERI-----------WEAVRTTE 317

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 377 QKIR--RLIKNDFVSAFA----EVDVILGPTTPNPAWKIgekNDDPVSqyLEdIYTITA----NLAGLPG---LSMPAGF 443
Cdd:PLN02722 318 EKIDacQSVKTELRAALTtllgEFGVLVIPTVPGPPPKL---QADPTT--LE-SFRARAfsllSIAGVSGfcqVSIPLGL 391

                        410       420
                 ....*....|....*....|...
gi 496673430 444 VDGLPVGVQLLAPYFQEGRLLNV 466
Cdd:PLN02722 392 HDNLPVSVSLLAKHGSDGFLLNL 414
PRK06565 PRK06565
amidase; Validated
 4-298 9.29e-23

amidase; Validated


Pssm-ID: 180626  Cd Length: 566  Bit Score: 101.38  E-value: 9.29e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430   4 QLTLAEIARALADKQFSAEELTRTLLGRIRQLD-----PQLNSFISITDDlAIAQAKAADERRANGEN-GALLGAPIAHK 77
Cdd:PRK06565   6 EVSIAELRAALESGRTTAVELVKAYLARIDAYDgpatgTALNAVVVRNPD-ALKEAEASDARRARGETlGPLDGIPYTAK 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430  78 DLFCTQGVRTSCGSKMLDNFVSPYDATVVEKLTAAGAVTLGKLNMDEFAMGSSnQSSHYGAVNNPWSLDRVPGGSSGGSA 157
Cdd:PRK06565  85 DSYLVKGLTAASGSPAFKDLVAQRDAFTIERLRAAGAICLGKTNMPPMANGGM-QRGVYGRAESPYNAAYLTAPFASGSS 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 158 AAvaarllpAATGT-----------DTGGSIRQPAALTNLTGIKPTYGRVSRWGMIAYASSLDQGGPLARTAEDCALMLG 226
Cdd:PRK06565 164 NG-------AGTATaasfsafglaeETWSSGRGPASNNGLCAYTPSRGVISVRGNWPLTPTMDVVVPYARTMADLLEVLD 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 496673430 227 VMAGFDPK---------------DSTSVEQPVDDYLAALQKPLSGLRIGLPREYFGAGLDS--------------RIA-- 275
Cdd:PRK06565 237 VIVADDPDtrgdlwrlqpwvpipKASEVRPASYLALAAGADALKGKRFGVPRMYINADPDAgtsenpgiggptgqRIHtr 316

                        330       340
                 ....*....|....*....|....*..
gi 496673430 276 DAVLAVVE----ELKTLGATVKDISLP 298
Cdd:PRK06565 317 PSVIDLWEaarrALEAAGAEVIEVDFP 343
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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