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Conserved domains on  [gi|492273001|ref|WP_005795962|]
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MalY/PatB family protein [Bacteroides fragilis]

Protein Classification

MalY/PatB family protein( domain architecture ID 11439426)

MalY/PatB family protein acts as a beta-cystathionase, catalyzing the transformation of cystathionine to homocysteine, similar to Escherichia coli MalY and Bacillus subtilis PatB; belongs to the pyridoxal phosphate (PLP)-dependent aminotransferase superfamily

EC:  4.4.1.13
Gene Ontology:  GO:0004121|GO:0030170|GO:0009086
PubMed:  11933250|17109392
SCOP:  3000954

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
MalY COG1168
Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor ...
1-386 0e+00

Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism, General function prediction only];


:

Pssm-ID: 440782  Cd Length: 387  Bit Score: 621.73  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001   1 MKYNFDEVIERRGTDSVKYDAVSERWGRSDLLPMWVADMDFRTPPFVIEAIRRRLDHEVLGYTFACEAWYTSIINWQKER 80
Cdd:COG1168    1 MKYDFDTIIDRRGTGSVKWDGLEDRFGGEDVLPMWVADMDFATPPAVIEALKERVEHGVFGYTAPPDEYYEAIIDWLKRR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  81 HGWNVTREMLTFTPGIVRGLAFALQCFTAPGDKVMVMPPVYHPFFLVTEHNHREVVYSPLLLKDGQYQIDFERFRADVK- 159
Cdd:COG1168   81 HGWEIDPEWIVFTPGVVPGLALAIRAFTEPGDGVLIQTPVYPPFFKAIENNGRELVENPLILEDGRYRIDFDDLEAKLDp 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 160 GCKMLILSNPHNPGGRVWTREELAEIAEICFDNQVLVISDEIHADLTLPGYTHPTFALVSEKARRNSLVFMSPSKAFNMP 239
Cdd:COG1168  161 GVKLLLLCNPHNPTGRVWTREELERLAELCERHDVLVISDEIHADLVLPGHKHTPFASLSEEAADRTITLTSPSKTFNLA 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 240 GLASSYCIIEDEAIRHRFQTYMEASEFSEGHLFAYLGVAAAYSNGTEWLDQALEYIQENIDFTDEYLKTHIPAIRMIRPQ 319
Cdd:COG1168  241 GLKASYAIIPNPALRARFARALEGLGLPSPNVLGLVATEAAYREGEEWLDELLAYLRGNRDLLAEFLAEHLPGVKVTPPE 320
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492273001 320 ASYLIFLDCRGMGVSQKELVDFFVDGAHLALNDGAMFGKEGEGFMRLNVACPRSVLRQALDQIKEAY 386
Cdd:COG1168  321 ATYLAWLDCRALGLDDEELAEFLLEKAGVALSDGATFGEGGEGFVRLNFACPRAVLEEALERLAKAL 387
 
Name Accession Description Interval E-value
MalY COG1168
Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor ...
1-386 0e+00

Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism, General function prediction only];


Pssm-ID: 440782  Cd Length: 387  Bit Score: 621.73  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001   1 MKYNFDEVIERRGTDSVKYDAVSERWGRSDLLPMWVADMDFRTPPFVIEAIRRRLDHEVLGYTFACEAWYTSIINWQKER 80
Cdd:COG1168    1 MKYDFDTIIDRRGTGSVKWDGLEDRFGGEDVLPMWVADMDFATPPAVIEALKERVEHGVFGYTAPPDEYYEAIIDWLKRR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  81 HGWNVTREMLTFTPGIVRGLAFALQCFTAPGDKVMVMPPVYHPFFLVTEHNHREVVYSPLLLKDGQYQIDFERFRADVK- 159
Cdd:COG1168   81 HGWEIDPEWIVFTPGVVPGLALAIRAFTEPGDGVLIQTPVYPPFFKAIENNGRELVENPLILEDGRYRIDFDDLEAKLDp 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 160 GCKMLILSNPHNPGGRVWTREELAEIAEICFDNQVLVISDEIHADLTLPGYTHPTFALVSEKARRNSLVFMSPSKAFNMP 239
Cdd:COG1168  161 GVKLLLLCNPHNPTGRVWTREELERLAELCERHDVLVISDEIHADLVLPGHKHTPFASLSEEAADRTITLTSPSKTFNLA 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 240 GLASSYCIIEDEAIRHRFQTYMEASEFSEGHLFAYLGVAAAYSNGTEWLDQALEYIQENIDFTDEYLKTHIPAIRMIRPQ 319
Cdd:COG1168  241 GLKASYAIIPNPALRARFARALEGLGLPSPNVLGLVATEAAYREGEEWLDELLAYLRGNRDLLAEFLAEHLPGVKVTPPE 320
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492273001 320 ASYLIFLDCRGMGVSQKELVDFFVDGAHLALNDGAMFGKEGEGFMRLNVACPRSVLRQALDQIKEAY 386
Cdd:COG1168  321 ATYLAWLDCRALGLDDEELAEFLLEKAGVALSDGATFGEGGEGFVRLNFACPRAVLEEALERLAKAL 387
C_S_lyase_PatB TIGR04350
putative C-S lyase; Members of this subfamily are probable C-S lyases from a family of ...
5-385 1.41e-174

putative C-S lyase; Members of this subfamily are probable C-S lyases from a family of pyridoxal phosphate-dependent enzymes that tend to be (mis)annotated as probable aminotransferases. One member is PatB of Bacillus subtilis, a proven C-S-lyase. Another is the virulence factor cystalysin from Treponema denticola, whose hemolysin activity may stem from H2S production. Members of the seed alignment occur next to examples of the enzyme 5-histidylcysteine sulfoxide synthase, from ovothiol A biosynthesis, and would be expected to perform a C-S cleavage of 5-histidylcysteine sulfoxide to leave 1-methyl-4-mercaptohistidine (ovothiol A).


Pssm-ID: 275146  Cd Length: 384  Bit Score: 491.83  E-value: 1.41e-174
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001    5 FDEVIERRGTDSVKYDAVSERWGRSDLLPMWVADMDFRTPPFVIEAIRRRLDHEVLGYTFACEAWYTSIINWQKERHGWN 84
Cdd:TIGR04350   1 FDRVIDRHGTDSEKYDLREERFGRADVLPMWVADMDFATPPAVLEALKQRLEHPVFGYTLPPDSLYAAVINWLAQRHGWQ 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001   85 VTREMLTFTPGIVRGLAFALQCFTAPGDKVMVMPPVYHPFFLVTEHNHREVVYSPLLLKDGQYQIDFERFRADV-KGCKM 163
Cdd:TIGR04350  81 IDPEDIVFLPGVVPSLFAAVRALTAPGEGVIVQTPVYPPFLSAVKSNGRELVLNPLKLDEGRYRFDLEDLEDAItEKARL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  164 LILSNPHNPGGRVWTREELAEIAEICFDNQVLVISDEIHADLTLPGYTHPTFALVSEKARRNSLVFMSPSKAFNMPGLAS 243
Cdd:TIGR04350 161 LLLCSPHNPVGRVWTREELTRLAELCLRHNVVVVSDEIHADLVYPPNKHIPLASLSPEPAERTVTLLSPGKTFNIAGLNI 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  244 SYCIIEDEAIRHRFQTYMEASEFSEGHLFAYLGVAAAYSNGTEWLDQALEYIQENIDFTDEYLKTHIPAIRMIRPQASYL 323
Cdd:TIGR04350 241 SFAIIPNPELRRAFQEAAQRVHIQHGNLFGYVAFEAAYRDGEPWLDALLAYLRGNRDLVEEFIAKRLPQIRVRPPEATYL 320
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492273001  324 IFLDCRGMGVSQKELVDFFVDGAHLALNDGAMFGKEGEGFMRLNVACPRSVLRQALDQIKEA 385
Cdd:TIGR04350 321 AWLDCRALGLDDADLRAFFIEQAGLGLNPGISFGDGGSGFMRLNFGCPRSTLEQALERLRQA 382
AAT_like cd00609
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ...
32-384 7.16e-86

Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.


Pssm-ID: 99734 [Multi-domain]  Cd Length: 350  Bit Score: 264.59  E-value: 7.16e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  32 LPMWVADMDFRTPPFVIEAIRR-RLDHEVLGYT--FACEAWYTSIINWQKERHGWNVTREMLTFTPGIVRGLAFALQCFT 108
Cdd:cd00609    1 IDLSIGEPDFPPPPEVLEALAAaALRAGLLGYYpdPGLPELREAIAEWLGRRGGVDVPPEEIVVTNGAQEALSLLLRALL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 109 APGDKVMVMPPVYHPFFLVTEHNHREVVYSPLLLKDGQYQIDFERFRADVKGCKMLILSNPHNPGGRVWTREELAEIAEI 188
Cdd:cd00609   81 NPGDEVLVPDPTYPGYEAAARLAGAEVVPVPLDEEGGFLLDLELLEAAKTPKTKLLYLNNPNNPTGAVLSEEELEELAEL 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 189 CFDNQVLVISDEIHADLTLPGYTHPtfALVSEKARRNSLVFMSPSKAFNMPGLASSYCIIEDEAIRHRFQTYMEASEFSe 268
Cdd:cd00609  161 AKKHGILIISDEAYAELVYDGEPPP--ALALLDAYERVIVLRSFSKTFGLPGLRIGYLIAPPEELLERLKKLLPYTTSG- 237
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 269 GHLFAYLGVAAAYSNGTEWLDQALEYIQENIDFTDEYLKTHIPAIRmIRPQASYLIFLDCRGMGVSqkELVDFFVDGAHL 348
Cdd:cd00609  238 PSTLSQAAAAAALDDGEEHLEELRERYRRRRDALLEALKELGPLVV-VKPSGGFFLWLDLPEGDDE--EFLERLLLEAGV 314
                        330       340       350
                 ....*....|....*....|....*....|....*.
gi 492273001 349 ALNDGAMFGKEGEGFMRLNVACPRSVLRQALDQIKE 384
Cdd:cd00609  315 VVRPGSAFGEGGEGFVRLSFATPEEELEEALERLAE 350
PRK06348 PRK06348
pyridoxal phosphate-dependent aminotransferase;
73-384 8.34e-30

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 180537  Cd Length: 384  Bit Score: 118.28  E-value: 8.34e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  73 IINWQKERHGWNVTREMLTFTPGIVRGLAFALQCFTAPGDKVMVMPPVYHPFFLVTEHNHREVVYSPLLLKDGqYQIDFE 152
Cdd:PRK06348  75 IIKYYSKNYDLSFKRNEIMATVGACHGMYLALQSILDPGDEVIIHEPYFTPYKDQIEMVGGKPIILETYEEDG-FQINVK 153
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 153 RFRADVKG-CKMLILSNPHNPGGRVWTREELAEIAEICFDNQVLVISDEIHADLTlpgYTHPTFALVS-EKARRNSLVFM 230
Cdd:PRK06348 154 KLEALITSkTKAIILNSPNNPTGAVFSKETLEEIAKIAIEYDLFIISDEVYDGFS---FYEDFVPMATlAGMPERTITFG 230
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 231 SPSKAFNMPGLASSYCIIEDEAIRhrfqtymEASEFSEGHLFAYLGV---AAAYS--NGTEWLDQALEYIQENIDFTDEY 305
Cdd:PRK06348 231 SFSKDFAMTGWRIGYVIAPDYIIE-------TAKIINEGICFSAPTIsqrAAIYAlkHRDTIVPLIKEEFQKRLEYAYKR 303
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 492273001 306 LKThIPAIRMIRPQASYLIFLDCRGMGVSQKELVDFFVDGAHLALNDGAMFGKEGEGFMRLNVACPRSVLRQALDQIKE 384
Cdd:PRK06348 304 IES-IPNLSLHPPKGSIYAFINIKKTGLSSVEFCEKLLKEAHVLVIPGKAFGESGEGYIRLACTVGIEVLEEAFNRIEK 381
Aminotran_1_2 pfam00155
Aminotransferase class I and II;
38-382 2.86e-29

Aminotransferase class I and II;


Pssm-ID: 395103 [Multi-domain]  Cd Length: 351  Bit Score: 116.25  E-value: 2.86e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001   38 DMDFRTPPFVIEAIRRRLDHEVL-------GYTFACEAwytsIINWQKERHGWNVTREM-LTFTPGIVRGLAFALQCFTA 109
Cdd:pfam00155  10 EYLGDTLPAVAKAEKDALAGGTRnlygptdGHPELREA----LAKFLGRSPVLKLDREAaVVFGSGAGANIEALIFLLAN 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  110 PGDKVmVMPPVYHPFFL-VTEHNHREVVYSPLLLKDGqYQIDFERFRADV-KGCKMLILSNPHNPGGRVWTREELAEIAE 187
Cdd:pfam00155  86 PGDAI-LVPAPTYASYIrIARLAGGEVVRYPLYDSND-FHLDFDALEAALkEKPKVVLHTSPHNPTGTVATLEELEKLLD 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  188 ICFDNQVLVISDEIHADLtlpGYTHPTFA--LVSEKARRNSLVFMSPSKAFNMPGLASSYCIIEDEAIRH--RFQTYMEA 263
Cdd:pfam00155 164 LAKEHNILLLVDEAYAGF---VFGSPDAVatRALLAEGPNLLVVGSFSKAFGLAGWRVGYILGNAAVISQlrKLARPFYS 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  264 SEFSeghlfAYLgVAAAYSN---GTEWLDQALEYIQENIDftdeYLKTHIPAIR--MIRPQASYLIFLDCRgmGVSQKEL 338
Cdd:pfam00155 241 STHL-----QAA-AAAALSDpllVASELEEMRQRIKERRD----YLRDGLQAAGlsVLPSQAGFFLLTGLD--PETAKEL 308
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*
gi 492273001  339 VDFFVDGAHLALNDGAMFGKegEGFMRLNVA-CPRSVLRQALDQI 382
Cdd:pfam00155 309 AQVLLEEVGVYVTPGSSPGV--PGWLRITVAgGTEEELEELLEAI 351
 
Name Accession Description Interval E-value
MalY COG1168
Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor ...
1-386 0e+00

Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism, General function prediction only];


Pssm-ID: 440782  Cd Length: 387  Bit Score: 621.73  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001   1 MKYNFDEVIERRGTDSVKYDAVSERWGRSDLLPMWVADMDFRTPPFVIEAIRRRLDHEVLGYTFACEAWYTSIINWQKER 80
Cdd:COG1168    1 MKYDFDTIIDRRGTGSVKWDGLEDRFGGEDVLPMWVADMDFATPPAVIEALKERVEHGVFGYTAPPDEYYEAIIDWLKRR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  81 HGWNVTREMLTFTPGIVRGLAFALQCFTAPGDKVMVMPPVYHPFFLVTEHNHREVVYSPLLLKDGQYQIDFERFRADVK- 159
Cdd:COG1168   81 HGWEIDPEWIVFTPGVVPGLALAIRAFTEPGDGVLIQTPVYPPFFKAIENNGRELVENPLILEDGRYRIDFDDLEAKLDp 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 160 GCKMLILSNPHNPGGRVWTREELAEIAEICFDNQVLVISDEIHADLTLPGYTHPTFALVSEKARRNSLVFMSPSKAFNMP 239
Cdd:COG1168  161 GVKLLLLCNPHNPTGRVWTREELERLAELCERHDVLVISDEIHADLVLPGHKHTPFASLSEEAADRTITLTSPSKTFNLA 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 240 GLASSYCIIEDEAIRHRFQTYMEASEFSEGHLFAYLGVAAAYSNGTEWLDQALEYIQENIDFTDEYLKTHIPAIRMIRPQ 319
Cdd:COG1168  241 GLKASYAIIPNPALRARFARALEGLGLPSPNVLGLVATEAAYREGEEWLDELLAYLRGNRDLLAEFLAEHLPGVKVTPPE 320
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492273001 320 ASYLIFLDCRGMGVSQKELVDFFVDGAHLALNDGAMFGKEGEGFMRLNVACPRSVLRQALDQIKEAY 386
Cdd:COG1168  321 ATYLAWLDCRALGLDDEELAEFLLEKAGVALSDGATFGEGGEGFVRLNFACPRAVLEEALERLAKAL 387
C_S_lyase_PatB TIGR04350
putative C-S lyase; Members of this subfamily are probable C-S lyases from a family of ...
5-385 1.41e-174

putative C-S lyase; Members of this subfamily are probable C-S lyases from a family of pyridoxal phosphate-dependent enzymes that tend to be (mis)annotated as probable aminotransferases. One member is PatB of Bacillus subtilis, a proven C-S-lyase. Another is the virulence factor cystalysin from Treponema denticola, whose hemolysin activity may stem from H2S production. Members of the seed alignment occur next to examples of the enzyme 5-histidylcysteine sulfoxide synthase, from ovothiol A biosynthesis, and would be expected to perform a C-S cleavage of 5-histidylcysteine sulfoxide to leave 1-methyl-4-mercaptohistidine (ovothiol A).


Pssm-ID: 275146  Cd Length: 384  Bit Score: 491.83  E-value: 1.41e-174
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001    5 FDEVIERRGTDSVKYDAVSERWGRSDLLPMWVADMDFRTPPFVIEAIRRRLDHEVLGYTFACEAWYTSIINWQKERHGWN 84
Cdd:TIGR04350   1 FDRVIDRHGTDSEKYDLREERFGRADVLPMWVADMDFATPPAVLEALKQRLEHPVFGYTLPPDSLYAAVINWLAQRHGWQ 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001   85 VTREMLTFTPGIVRGLAFALQCFTAPGDKVMVMPPVYHPFFLVTEHNHREVVYSPLLLKDGQYQIDFERFRADV-KGCKM 163
Cdd:TIGR04350  81 IDPEDIVFLPGVVPSLFAAVRALTAPGEGVIVQTPVYPPFLSAVKSNGRELVLNPLKLDEGRYRFDLEDLEDAItEKARL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  164 LILSNPHNPGGRVWTREELAEIAEICFDNQVLVISDEIHADLTLPGYTHPTFALVSEKARRNSLVFMSPSKAFNMPGLAS 243
Cdd:TIGR04350 161 LLLCSPHNPVGRVWTREELTRLAELCLRHNVVVVSDEIHADLVYPPNKHIPLASLSPEPAERTVTLLSPGKTFNIAGLNI 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  244 SYCIIEDEAIRHRFQTYMEASEFSEGHLFAYLGVAAAYSNGTEWLDQALEYIQENIDFTDEYLKTHIPAIRMIRPQASYL 323
Cdd:TIGR04350 241 SFAIIPNPELRRAFQEAAQRVHIQHGNLFGYVAFEAAYRDGEPWLDALLAYLRGNRDLVEEFIAKRLPQIRVRPPEATYL 320
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492273001  324 IFLDCRGMGVSQKELVDFFVDGAHLALNDGAMFGKEGEGFMRLNVACPRSVLRQALDQIKEA 385
Cdd:TIGR04350 321 AWLDCRALGLDDADLRAFFIEQAGLGLNPGISFGDGGSGFMRLNFGCPRSTLEQALERLRQA 382
AAT_like cd00609
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ...
32-384 7.16e-86

Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.


Pssm-ID: 99734 [Multi-domain]  Cd Length: 350  Bit Score: 264.59  E-value: 7.16e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  32 LPMWVADMDFRTPPFVIEAIRR-RLDHEVLGYT--FACEAWYTSIINWQKERHGWNVTREMLTFTPGIVRGLAFALQCFT 108
Cdd:cd00609    1 IDLSIGEPDFPPPPEVLEALAAaALRAGLLGYYpdPGLPELREAIAEWLGRRGGVDVPPEEIVVTNGAQEALSLLLRALL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 109 APGDKVMVMPPVYHPFFLVTEHNHREVVYSPLLLKDGQYQIDFERFRADVKGCKMLILSNPHNPGGRVWTREELAEIAEI 188
Cdd:cd00609   81 NPGDEVLVPDPTYPGYEAAARLAGAEVVPVPLDEEGGFLLDLELLEAAKTPKTKLLYLNNPNNPTGAVLSEEELEELAEL 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 189 CFDNQVLVISDEIHADLTLPGYTHPtfALVSEKARRNSLVFMSPSKAFNMPGLASSYCIIEDEAIRHRFQTYMEASEFSe 268
Cdd:cd00609  161 AKKHGILIISDEAYAELVYDGEPPP--ALALLDAYERVIVLRSFSKTFGLPGLRIGYLIAPPEELLERLKKLLPYTTSG- 237
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 269 GHLFAYLGVAAAYSNGTEWLDQALEYIQENIDFTDEYLKTHIPAIRmIRPQASYLIFLDCRGMGVSqkELVDFFVDGAHL 348
Cdd:cd00609  238 PSTLSQAAAAAALDDGEEHLEELRERYRRRRDALLEALKELGPLVV-VKPSGGFFLWLDLPEGDDE--EFLERLLLEAGV 314
                        330       340       350
                 ....*....|....*....|....*....|....*.
gi 492273001 349 ALNDGAMFGKEGEGFMRLNVACPRSVLRQALDQIKE 384
Cdd:cd00609  315 VVRPGSAFGEGGEGFVRLSFATPEEELEEALERLAE 350
AspB COG0436
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; ...
30-385 2.14e-66

Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis


Pssm-ID: 440205 [Multi-domain]  Cd Length: 387  Bit Score: 215.76  E-value: 2.14e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  30 DLLPMWVADMDFRTPPFVIEAIRRRLDHEVLGYTFA------CEAwytsIINWQKERHGWNVTREMLTFTPGIVRGLAFA 103
Cdd:COG0436   31 DVIDLGIGEPDFPTPDHIREAAIEALDDGVTGYTPSagipelREA----IAAYYKRRYGVDLDPDEILVTNGAKEALALA 106
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 104 LQCFTAPGDKVmVMP----PVYHPFflvTEHNHREVVYSPLLLKDGqYQIDFERFRADVK-GCKMLILSNPHNPGGRVWT 178
Cdd:COG0436  107 LLALLNPGDEV-LVPdpgyPSYRAA---VRLAGGKPVPVPLDEENG-FLPDPEALEAAITpRTKAIVLNSPNNPTGAVYS 181
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 179 REELAEIAEICFDNQVLVISDEIHADLTLPGYTHPTFALVSEkARRNSLVFMSPSKAFNMPGLASSYCIIEDEAIRH--R 256
Cdd:COG0436  182 REELEALAELAREHDLLVISDEIYEELVYDGAEHVSILSLPG-LKDRTIVINSFSKSYAMTGWRIGYAVGPPELIAAllK 260
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 257 FQTYMEASEFSeghlFAYLGVAAAYSNGTEWLDQALEYIQENIDFTDEYLKTHipAIRMIRPQASYLIFLDCRGMGVSQK 336
Cdd:COG0436  261 LQSNLTSCAPT----PAQYAAAAALEGPQDYVEEMRAEYRRRRDLLVEGLNEI--GLSVVKPEGAFYLFADVPELGLDSE 334
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*....
gi 492273001 337 ELVDFFVDGAHLALNDGAMFGKEGEGFMRLNVACPRSVLRQALDQIKEA 385
Cdd:COG0436  335 EFAERLLEEAGVAVVPGSAFGPAGEGYVRISYATSEERLEEALERLARF 383
PRK06348 PRK06348
pyridoxal phosphate-dependent aminotransferase;
73-384 8.34e-30

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 180537  Cd Length: 384  Bit Score: 118.28  E-value: 8.34e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  73 IINWQKERHGWNVTREMLTFTPGIVRGLAFALQCFTAPGDKVMVMPPVYHPFFLVTEHNHREVVYSPLLLKDGqYQIDFE 152
Cdd:PRK06348  75 IIKYYSKNYDLSFKRNEIMATVGACHGMYLALQSILDPGDEVIIHEPYFTPYKDQIEMVGGKPIILETYEEDG-FQINVK 153
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 153 RFRADVKG-CKMLILSNPHNPGGRVWTREELAEIAEICFDNQVLVISDEIHADLTlpgYTHPTFALVS-EKARRNSLVFM 230
Cdd:PRK06348 154 KLEALITSkTKAIILNSPNNPTGAVFSKETLEEIAKIAIEYDLFIISDEVYDGFS---FYEDFVPMATlAGMPERTITFG 230
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 231 SPSKAFNMPGLASSYCIIEDEAIRhrfqtymEASEFSEGHLFAYLGV---AAAYS--NGTEWLDQALEYIQENIDFTDEY 305
Cdd:PRK06348 231 SFSKDFAMTGWRIGYVIAPDYIIE-------TAKIINEGICFSAPTIsqrAAIYAlkHRDTIVPLIKEEFQKRLEYAYKR 303
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 492273001 306 LKThIPAIRMIRPQASYLIFLDCRGMGVSQKELVDFFVDGAHLALNDGAMFGKEGEGFMRLNVACPRSVLRQALDQIKE 384
Cdd:PRK06348 304 IES-IPNLSLHPPKGSIYAFINIKKTGLSSVEFCEKLLKEAHVLVIPGKAFGESGEGYIRLACTVGIEVLEEAFNRIEK 381
Aminotran_1_2 pfam00155
Aminotransferase class I and II;
38-382 2.86e-29

Aminotransferase class I and II;


Pssm-ID: 395103 [Multi-domain]  Cd Length: 351  Bit Score: 116.25  E-value: 2.86e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001   38 DMDFRTPPFVIEAIRRRLDHEVL-------GYTFACEAwytsIINWQKERHGWNVTREM-LTFTPGIVRGLAFALQCFTA 109
Cdd:pfam00155  10 EYLGDTLPAVAKAEKDALAGGTRnlygptdGHPELREA----LAKFLGRSPVLKLDREAaVVFGSGAGANIEALIFLLAN 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  110 PGDKVmVMPPVYHPFFL-VTEHNHREVVYSPLLLKDGqYQIDFERFRADV-KGCKMLILSNPHNPGGRVWTREELAEIAE 187
Cdd:pfam00155  86 PGDAI-LVPAPTYASYIrIARLAGGEVVRYPLYDSND-FHLDFDALEAALkEKPKVVLHTSPHNPTGTVATLEELEKLLD 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  188 ICFDNQVLVISDEIHADLtlpGYTHPTFA--LVSEKARRNSLVFMSPSKAFNMPGLASSYCIIEDEAIRH--RFQTYMEA 263
Cdd:pfam00155 164 LAKEHNILLLVDEAYAGF---VFGSPDAVatRALLAEGPNLLVVGSFSKAFGLAGWRVGYILGNAAVISQlrKLARPFYS 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  264 SEFSeghlfAYLgVAAAYSN---GTEWLDQALEYIQENIDftdeYLKTHIPAIR--MIRPQASYLIFLDCRgmGVSQKEL 338
Cdd:pfam00155 241 STHL-----QAA-AAAALSDpllVASELEEMRQRIKERRD----YLRDGLQAAGlsVLPSQAGFFLLTGLD--PETAKEL 308
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*
gi 492273001  339 VDFFVDGAHLALNDGAMFGKegEGFMRLNVA-CPRSVLRQALDQI 382
Cdd:pfam00155 309 AQVLLEEVGVYVTPGSSPGV--PGWLRITVAgGTEEELEELLEAI 351
PRK06108 PRK06108
pyridoxal phosphate-dependent aminotransferase;
27-383 2.38e-27

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 180404  Cd Length: 382  Bit Score: 111.57  E-value: 2.38e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  27 GRSDLLPMWVADMDFRTPPFVIEAIRRRLDHevlGYTFaceawYT----------SIINWQKERHGWNVTREMLTFTPGI 96
Cdd:PRK06108  22 GREGVLPLWFGESDLPTPDFIRDAAAAALAD---GETF-----YThnlgipelreALARYVSRLHGVATPPERIAVTSSG 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  97 VRGLAFALQCFTAPGDKVMVMPPVYHPFFLVTEHNHREVVYSPLLLKDGQYQIDFERFRADV-KGCKMLILSNPHNPGGR 175
Cdd:PRK06108  94 VQALMLAAQALVGPGDEVVAVTPLWPNLVAAPKILGARVVCVPLDFGGGGWTLDLDRLLAAItPRTRALFINSPNNPTGW 173
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 176 VWTREELAEIAEICFDNQVLVISDEIHADLT-LPGYTHPTFALVSEKARRnsLVFM-SPSKAFNMPGLASSYCIIEDEAI 253
Cdd:PRK06108 174 TASRDDLRAILAHCRRHGLWIVADEVYERLYyAPGGRAPSFLDIAEPDDR--IIFVnSFSKNWAMTGWRLGWLVAPPALG 251
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 254 RHrfqtyMEA-SEFSEGHLFAYL---GVAAaysngtewLDQALEYIQENI-------DFTDEYLKThIPAIRMIRPQASY 322
Cdd:PRK06108 252 QV-----LEKlIEYNTSCVAQFVqraAVAA--------LDEGEDFVAELVarlrrsrDHLVDALRA-LPGVEVAKPDGAM 317
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 492273001 323 LIFLDCRGMGVSQKELVDfFVDGAHLALNDGAMFGKEGEGFMRLNVACPRSVLRQALDQIK 383
Cdd:PRK06108 318 YAFFRIPGVTDSLALAKR-LVDEAGLGLAPGTAFGPGGEGFLRWCFARDPARLDEAVERLR 377
PRK05764 PRK05764
aspartate aminotransferase; Provisional
40-384 2.88e-27

aspartate aminotransferase; Provisional


Pssm-ID: 235596  Cd Length: 393  Bit Score: 111.37  E-value: 2.88e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  40 DFRTPPFVIEAIRRRLDHEVLGYTFAC------EAwytsIINWQKERHGWNVTREMLTFTPGIVRGLAFALQCFTAPGDK 113
Cdd:PRK05764  42 DFDTPEHIKEAAIEALDDGKTKYTPAAgipelrEA----IAAKLKRDNGLDYDPSQVIVTTGAKQALYNAFMALLDPGDE 117
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 114 VMVMPPVYhpfflVTehnHRE--------VVYSPLLLKDGqYQIDFERFRADV-KGCKMLILSNPHNPGGRVWTREELAE 184
Cdd:PRK05764 118 VIIPAPYW-----VS---YPEmvklaggvPVFVPTGEENG-FKLTVEQLEAAItPKTKALILNSPSNPTGAVYSPEELEA 188
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 185 IAEICFDNQVLVISDEIHADLTLPGYTHPTFALVSEKARRNSLVFMSPSKAFNMPGLASSYCIIEDEAIR--HRFQTYM- 261
Cdd:PRK05764 189 IADVAVEHDIWVLSDEIYEKLVYDGAEFTSIASLSPELRDRTITVNGFSKAYAMTGWRLGYAAGPKELIKamSKLQSHSt 268
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 262 -EASEFSEghlfaYLGVAAaysngtewLDQALEYIQENIDFTDEYLKT------HIPAIRMIRPQASYLIFLDCRG---- 330
Cdd:PRK05764 269 sNPTSIAQ-----YAAVAA--------LNGPQDEVEEMRQAFEERRDLmvdglnEIPGLECPKPEGAFYVFPNVSKllgk 335
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....
gi 492273001 331 MGVSQKELVDFFVDGAHLALNDGAMFGKegEGFMRLNVACPRSVLRQALDQIKE 384
Cdd:PRK05764 336 SITDSLEFAEALLEEAGVAVVPGIAFGA--PGYVRLSYATSLEDLEEGLERIER 387
PRK08361 PRK08361
aspartate aminotransferase; Provisional
30-387 1.28e-24

aspartate aminotransferase; Provisional


Pssm-ID: 236248 [Multi-domain]  Cd Length: 391  Bit Score: 104.19  E-value: 1.28e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  30 DLLPMWVADMDFRTPPFVIEAIRRRLDHEVLGYT--FACEAWYTSIINWQKERHGWNVTREMLTFTPGIVRGLAFALQCF 107
Cdd:PRK08361  34 NVISLGIGEPDFDTPKNIKEAAKRALDEGWTHYTpnAGIPELREAIAEYYKKFYGVDVDVDNVIVTAGAYEATYLAFESL 113
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 108 TAPGDKVMVMPPVYHPFFLVTEHNHREVVYSPLLlKDGQYQIDF-ERFRADVKGCKMLILSNPHNPGGRVWTREELAEIA 186
Cdd:PRK08361 114 LEEGDEVIIPDPAFVCYVEDAKIAEAKPIRIPLR-EENEFQPDPdELLELITKRTRMIVINYPNNPTGATLDKEVAKAIA 192
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 187 EICFDNQVLVISDEIHADLTLPGYTH-PTFALVSEkarrNSLVFMSPSKAFNMPGLASSYCIIEDEAIRHRFQTYmeasE 265
Cdd:PRK08361 193 DIAEDYNIYILSDEPYEHFLYEGAKHyPMIKYAPD----NTILANSFSKTFAMTGWRLGFVIAPEQVIKDMIKLH----A 264
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 266 FSEGHLFAYLGVA--AAYSNGTEWldQALEYIQENID----FTDEYLKtHIPAIRMIRPQASYLIFLDCRGMGVSQKELV 339
Cdd:PRK08361 265 YIIGNVASFVQIAgiEALRSKESW--KAVEEMRKEYNerrkLVLKRLK-EMPHIKVFEPKGAFYVFANIDETGMSSEDFA 341
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*...
gi 492273001 340 DFFVDGAHLALNDGAMFGKEGEGFMRLNVACPRSVLRQALDQIKEAYE 387
Cdd:PRK08361 342 EWLLEKARVVVIPGTAFGKAGEGYIRISYATSKEKLIEAMERMEKALE 389
PRK07309 PRK07309
pyridoxal phosphate-dependent aminotransferase;
40-384 1.45e-22

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 235985  Cd Length: 391  Bit Score: 98.26  E-value: 1.45e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  40 DFRTPPFVIEAIRRRLDhevlgytfACEAWYTSII----------NWQKERHG--WNVTREMLTfTPGIVRGLAFALQCF 107
Cdd:PRK07309  41 DFTTPDHVKEAAKRAID--------ANQSHYTGMAgllelrqaaaDFVKEKYNldYAPENEILV-TIGATEALSASLTAI 111
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 108 TAPGDKVMVMPPVYHPFFLVTEHNHREVVY----------SPLLLkdgqyqidfERFRADVKG-CKMLILSNPHNPGGRV 176
Cdd:PRK07309 112 LEPGDKVLLPAPAYPGYEPIVNLVGAEIVEidttendfvlTPEML---------EKAILEQGDkLKAVILNYPANPTGVT 182
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 177 WTREELAEIAEICFDNQVLVISDEIHADLTLPGYTHPTFAlvsEKARRNSLVFMSPSKAFNMPG------LASSycIIED 250
Cdd:PRK07309 183 YSREQIKALADVLKKYDIFVISDEVYSELTYTGEPHVSIA---EYLPDQTILINGLSKSHAMTGwrigliFAPA--EFTA 257
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 251 EAIR-HRfqtYM--EASEFSEghlfaYLGVAAaYSNGTewlDQAL----EYIQENiDFTdeYLKTHIPAIRMIRPQASYL 323
Cdd:PRK07309 258 QLIKsHQ---YLvtAATTMAQ-----FAAVEA-LTNGK---DDALpmkkEYIKRR-DYI--IEKMTDLGFKIIKPDGAFY 322
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 492273001 324 IFLDCRGmGVSQKELvDFFVDGAH---LALNDGAMFGKEGEGFMRLNVACPRSVLRQALDQIKE 384
Cdd:PRK07309 323 IFAKIPA-GYNQDSF-KFLQDFARkkaVAFIPGAAFGPYGEGYVRLSYAASMETIKEAMKRLKE 384
PRK07777 PRK07777
putative succinyldiaminopimelate transaminase DapC;
44-332 6.36e-21

putative succinyldiaminopimelate transaminase DapC;


Pssm-ID: 236095 [Multi-domain]  Cd Length: 387  Bit Score: 93.18  E-value: 6.36e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  44 PPFVIEAIRRRLDHEVLGYT--FACEAWYTSIINWQKERHG--WNVTREMLTfTPGIVRGLAFALQCFTAPGDKVMVMPP 119
Cdd:PRK07777  39 PPEMLEAAQEAIAGGVNQYPpgPGIPELRAAIAAQRRRRYGleYDPDTEVLV-TVGATEAIAAAVLGLVEPGDEVLLIEP 117
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 120 VYHPFFLVTE--HNHREVVysPLLLKDGQYQIDFERFRADV-KGCKMLILSNPHNPGGRVWTREELAEIAEICFDNQVLV 196
Cdd:PRK07777 118 YYDSYAAVIAmaGAHRVPV--PLVPDGRGFALDLDALRAAVtPRTRALIVNSPHNPTGTVLTAAELAAIAELAVEHDLLV 195
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 197 ISDEIHADLTLPGYTHPTFALVSEKARRnSLVFMSPSKAFNMPG------LASSYCIiedEAIR--HRFQTYMEASEFSe 268
Cdd:PRK07777 196 ITDEVYEHLVFDGARHLPLATLPGMRER-TVTISSAAKTFNVTGwkigwaCGPAPLI---AAVRaaKQYLTYVGGAPFQ- 270
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 492273001 269 ghlfayLGVAAAYSNGTEWLDQALEYIQENIDF-----TDEYLKTHipairmiRPQASYLIFLDCRGMG 332
Cdd:PRK07777 271 ------PAVAHALDHEDAWVAALRDSLQAKRDRlaaglAEAGFEVH-------DSAGTYFLCADPRPLG 326
tyr_nico_aTase TIGR01265
tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal ...
41-387 1.42e-20

tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal phosphate-dependent enzymes includes known examples of both tyrosine aminotransferase from animals and nicotianamine aminotransferase from barley.


Pssm-ID: 188123  Cd Length: 403  Bit Score: 92.40  E-value: 1.42e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001   41 FRTPPFVIEAIRRRLDHE-------VLGYTFACEAwytsIINWQKERHGWNVTREMLTFTPGIVRGLAFALQCFTAPGDK 113
Cdd:TIGR01265  47 LRTDPEAEEAVKDALRSGkfngyapSVGALAAREA----VAEYLSSDLPGKLTADDVVLTSGCSQAIEICIEALANPGAN 122
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  114 VMVMPPVYHPFFLVTEHNHREVVYSPLLlKDGQYQIDFERFR--ADVKgCKMLILSNPHNPGGRVWTREELAEIAEICFD 191
Cdd:TIGR01265 123 ILVPRPGFPLYDTRAAFSGLEVRLYDLL-PEKDWEIDLDGLEslADEK-TVAIVVINPSNPCGSVFSRDHLQKIAEVAEK 200
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  192 NQVLVISDEIHADLTLPGYTHPTFALVSEKARRnsLVFMSPSKAFNMPGLASSYCIIED----------EAIRHRFQTYM 261
Cdd:TIGR01265 201 LGIPIIADEIYGHMVFGDAPFIPMASFASIVPV--LSLGGISKRWVVPGWRLGWIIIHDphgifrdtvlQGLKNLLQRIL 278
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  262 EASEFSEGHLFAYLGVAAAysngtEWLDQALEYIQENIDFTDEYLKtHIPAIRMIRPQ-ASYLIFLDCRGMGVSQKELVD 340
Cdd:TIGR01265 279 GPATIVQGALPDILENTPQ-----EFFDGKISVLKSNAELCYEELK-DIPGLVCPKPEgAMYLMVKLELELFPEIKDDVD 352
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|
gi 492273001  341 FFVDGA---HLALNDGAMFGKegEGFMRLNVACPRSVLRQALDQIKEAYE 387
Cdd:TIGR01265 353 FCEKLAreeSVICLPGSAFGL--PNWVRITITVPESMLEEACSRIKEFCE 400
PRK08363 PRK08363
alanine aminotransferase; Validated
40-384 7.86e-20

alanine aminotransferase; Validated


Pssm-ID: 181402  Cd Length: 398  Bit Score: 90.25  E-value: 7.86e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  40 DFRTPPFVIEAIRRRLD--HEVLGYTFACEAWYTSIINWQKERHGWNVTREMLTFTPGIVRGLAFALQCFTAPGDKVMVM 117
Cdd:PRK08363  44 DFQPPEHMKEAYCRAIKegHNYYGPSEGLPELREAIVKREKRKNGVDITPDDVRVTAAVTEALQLIFGALLDPGDEILIP 123
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 118 PPVYHPFF-LVTEHNHREVVYSPLLLKDGQYQIDFERFRADVKgCKMLILSNPHNPGGRVWTREELAEIAEICFDNQVLV 196
Cdd:PRK08363 124 GPSYPPYTgLVKFYGGVPVEYRTIEEEGWQPDIDDIRKKITEK-TKAIAVINPNNPTGALYEKKTLKEILDIAGEHDLPV 202
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 197 ISDEIHADLTLPGYTHPTFALVSEKarrNSLVFMSPSKAFNMPGLASSYCIIED---------EAIRHRFQTYMEASefs 267
Cdd:PRK08363 203 ISDEIYDLMTYEGKHVSPGSLTKDV---PVIVMNGLSKVYFATGWRLGYIYFVDpegklaevrEAIDKLARIRLCPN--- 276
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 268 eghLFAYLGVAAAYSNGTEWLDQALEYIQENIDFTDEYLkTHIPAIRMIRPQASYLIFLDCR-GMGVSQKELVDFFVDGA 346
Cdd:PRK08363 277 ---TPAQFAAIAGLTGPMDYLEEYMKKLKERRDYIYKRL-NEIPGISTTKPQGAFYIFPRIEeGPWKDDKEFVLDVLHEA 352
                        330       340       350
                 ....*....|....*....|....*....|....*...
gi 492273001 347 HLALNDGAMFGKEGEGFMRLNVACPRSVLRQALDQIKE 384
Cdd:PRK08363 353 HVLFVHGSGFGEYGAGHFRLVFLPPVEILEEAMDRFEE 390
PRK07681 PRK07681
LL-diaminopimelate aminotransferase;
40-383 4.17e-19

LL-diaminopimelate aminotransferase;


Pssm-ID: 181081  Cd Length: 399  Bit Score: 88.32  E-value: 4.17e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  40 DFRTPPFVIEAIRRRLDH-EVLGYTF-ACEAWYTSIINWQKERHGWNVTREM-LTFTPGIVRGLAFALQCFTAPGDKVMV 116
Cdd:PRK07681  43 DMPPADFVREEMVHTANQkESYGYTLsGIQEFHEAVTEYYNNTHNVILNADKeVLLLMGSQDGLVHLPMVYANPGDIILV 122
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 117 MPPVYhPFFLVTEHNHREVVYSPLLLKDGQYQIDFERFRADV-KGCKMLILSNPHNPGGRVWTREELAEIAEICFDNQVL 195
Cdd:PRK07681 123 PDPGY-TAYETGIQMAGATSYYMPLKKENDFLPDLELIPEEIaDKAKMMILNFPGNPVPAMAHEDFFKEVIAFAKKHNII 201
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 196 VISDEIHADLTLPGYTHPTFaLVSEKARRNSLVFMSPSKAFNMPGLASSYCIIEDEAIRH--RFQTYMEASEFseghLFA 273
Cdd:PRK07681 202 VVHDFAYAEFYFDGNKPISF-LSVPGAKEVGVEINSLSKSYSLAGSRIGYMIGNEEIVRAltQFKSNTDYGVF----LPI 276
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 274 YLGVAAAYSNGTEWLDQALEYIQENIDftdeylkTHIPAIRMI-----RPQASYLIFLDCRgMGVSQKELVDFFVDGAHL 348
Cdd:PRK07681 277 QKAACAALRNGAAFCEKNRGIYQERRD-------TLVDGFRTFgwnvdKPAGSMFVWAEIP-KGWTSLSFAYALMDRANV 348
                        330       340       350
                 ....*....|....*....|....*....|....*
gi 492273001 349 ALNDGAMFGKEGEGFMRLNVACPRSVLRQALDQIK 383
Cdd:PRK07681 349 VVTPGHAFGPHGEGFVRIALVQDEEVLQQAVENIR 383
tyr_amTase_E TIGR01264
tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found ...
43-384 4.43e-18

tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found in animals and Trypanosoma cruzi. It is the first enzyme of a pathway of tyrosine degradation via homogentisate. Several plant enzyme designated as probable tyrosine aminotransferases are very closely related to an experimentally demonstrated nicotianamine aminotransferase, an enzyme in a siderophore (iron uptake chelator) biosynthesis pathway. These plant sequences are excluded from the model seed and score between the trusted an noise cutoffs. [Energy metabolism, Amino acids and amines]


Pssm-ID: 273529 [Multi-domain]  Cd Length: 401  Bit Score: 85.22  E-value: 4.43e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001   43 TPPFVIEAIRRRLDHE-------VLGYTFACEAwytsIINWQKERHGwNVTREMLTFTPGIVRGLAFALQCFTAPGDKVM 115
Cdd:TIGR01264  49 TDPEVMQAMKDSLDSGkyngyapTVGALSAREA----IASYYHNPDG-PIEADDVVLCSGCSHAIEMCIAALANAGQNIL 123
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  116 VMPPVYHPFFLVTEHNHREVVYSPLLlKDGQYQIDFERFRA--DVKgCKMLILSNPHNPGGRVWTREELAEIAEICFDNQ 193
Cdd:TIGR01264 124 VPRPGFPLYETLAESMGIEVKLYNLL-PDKSWEIDLKQLESliDEK-TAALIVNNPSNPCGSVFSRQHLEEILAVAERQC 201
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  194 VLVISDEIHADLTLPGYTHPTFALVSEKARRNSLVFMspSKAFNMPGLASSYCIIED---------EAIRHRFQTYMEAS 264
Cdd:TIGR01264 202 LPIIADEIYGDMVFSGATFEPLASLSSTVPILSCGGL--AKRWLVPGWRLGWIIIHDrrgilrdirDGLVKLSQRILGPC 279
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  265 EFSEGHLFAYLgvaaaYSNGTEWLDQALEYIQENIDFTDEYLKtHIPAIRMIRPQASYLIFLdcrgmGVSQKELVDFFVD 344
Cdd:TIGR01264 280 TIVQGALPSIL-----LRTPQEYFDGTLSVLESNAMLCYGALA-AVPGLRPVMPSGAMYMMV-----GIEMEHFPEFKND 348
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*..
gi 492273001  345 GAHLA--LNDGAMFGKEGE-----GFMRLNVACPRSVLRQALDQIKE 384
Cdd:TIGR01264 349 VEFTErlVAEQSVFCLPGScfeypGFFRVVLTVPVVMMEEACSRIQE 395
PRK09082 PRK09082
methionine aminotransferase; Validated
79-247 6.10e-18

methionine aminotransferase; Validated


Pssm-ID: 181642 [Multi-domain]  Cd Length: 386  Bit Score: 84.58  E-value: 6.10e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  79 ERHGW--NVTREmLTFTPGIVRGLAFALQCFTAPGDKVMVMPPVYHPFFLVTEHNHREVVYSPLllKDGQYQIDFERFRA 156
Cdd:PRK09082  82 RLYGRqyDADSE-ITVTAGATEALFAAILALVRPGDEVIVFDPSYDSYAPAIELAGGRAVRVAL--QPPDFRVDWQRFAA 158
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 157 DVKG-CKMLILSNPHNPGGRVWTREELAEIAEICFDNQVLVISDEIHADLTLPGYTHPTFALVSEKARRnSLVFMSPSKA 235
Cdd:PRK09082 159 AISPrTRLIILNTPHNPSGTVWSAADMRALWQLIAGTDIYVLSDEVYEHIVFDGAGHASVLRHPELRER-AFVVSSFGKT 237
                        170
                 ....*....|..
gi 492273001 236 FNMPGLASSYCI 247
Cdd:PRK09082 238 YHVTGWKVGYCV 249
PRK07683 PRK07683
aminotransferase A; Validated
27-386 1.48e-17

aminotransferase A; Validated


Pssm-ID: 236075  Cd Length: 387  Bit Score: 83.62  E-value: 1.48e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  27 GRSDLLPMWVADMDFRTPPFVIEAIRRRLDHEVLGYTfaCEAWY----TSIINWQKERHGWNVTREM-LTFTPGIVRGLA 101
Cdd:PRK07683  26 NYDNLISLTIGQPDFPTPSHVKEAAKRAITENYTSYT--HNAGLlelrKAACNFVKDKYDLHYSPESeIIVTIGASEAID 103
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 102 FALQCFTAPGDKVMVMPPVY------------HPFFL-VTEHNHRevvYSPLLLKDgqyqidferfrADVKGCKMLILSN 168
Cdd:PRK07683 104 IAFRTILEPGTEVILPAPIYpgyepiirlcgaKPVFIdTRSTGFR---LTAEALEN-----------AITEKTRCVVLPY 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 169 PHNPGGRVWTREELAEIAEICFDNQVLVISDEIHADLTlpgYTHPTFALVS-EKARRNSLVFMSPSKAFNMPGLASSYCI 247
Cdd:PRK07683 170 PSNPTGVTLSKEELQDIADVLKDKNIFVLSDEIYSELV---YEQPHTSIAHfPEMREKTIVINGLSKSHSMTGWRIGFLF 246
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 248 IEDEAIRHRFQTYME----ASEFSEghlfaYLGVAAAYSNGTEWLDQALEYIqENIDFTDEYLKTHipAIRMIRPQASYL 323
Cdd:PRK07683 247 APSYLAKHILKVHQYnvtcASSISQ-----YAALEALTAGKDDAKMMRHQYK-KRRDYVYNRLISM--GLDVEKPTGAFY 318
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 492273001 324 IFLDCRGMGVSQKELVDFFVDGAHLALNDGAMFGKEGEGFMRLNVACPRSVLRQALDQIkEAY 386
Cdd:PRK07683 319 LFPSIGHFTMSSFDFALDLVEEAGLAVVPGSAFSEYGEGYVRLSYAYSIETLKEGLDRL-EAF 380
PRK09276 PRK09276
LL-diaminopimelate aminotransferase; Provisional
30-385 6.33e-17

LL-diaminopimelate aminotransferase; Provisional


Pssm-ID: 181749  Cd Length: 385  Bit Score: 81.50  E-value: 6.33e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  30 DLLPMWVADMDFRTPPFVIEAIRRRLD----HE------VLGYTFACEAWYtsiinwqKERHG--WNVTREMLTFTpGIV 97
Cdd:PRK09276  32 DVISLGIGDPDLPTPDHIIEAMCKAVEdpenHQypsyegMLEFRKAVADWY-------KRRFGveLDPETEVISLI-GSK 103
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  98 RGLAFALQCFTAPGDKVMVMPPVYHPFFLVTEHNHREVVYSPLLlKDGQYQIDFERFRADV-KGCKMLILSNPHNPGGRV 176
Cdd:PRK09276 104 EGIAHIPLAFVNPGDVVLVPDPGYPVYKIGTIFAGGEPYFMPLK-EENGFLPDLDAIPEDVaKKAKLMFINYPNNPTGAV 182
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 177 WTREELAEIAEICFDNQVLVISDEIHADLTLPGYTHPTFaLVSEKARRNSLVFMSPSKAFNMPGLASSYCIIEDEAIR-- 254
Cdd:PRK09276 183 ADLEFFEEVVDFAKKYDIIVCHDAAYSEIAYDGYKPPSF-LEVPGAKDVGIEFHSLSKTYNMTGWRIGFAVGNADLIAgl 261
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 255 HRFQTYMEASEFSEghlFAYLGVAAaysngtewLDQALEYIQENIDFTDEYLKTHIPAIRMI-----RPQASYLIFLDCR 329
Cdd:PRK09276 262 GKVKSNVDSGVFQA---IQEAGIAA--------LNGPQEVVEELRKIYQERRDILVEGLRKLglevePPKATFYVWAPVP 330
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 492273001 330 GmGVSQKELVDFFVDGAHLALNDGAMFGKEGEGFMRLNVACPRSVLRQALDQIKEA 385
Cdd:PRK09276 331 K-GYTSAEFATLLLDKAGVVVTPGNGFGEYGEGYFRIALTVPDERIEEAVERIKKL 385
HisC COG0079
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid ...
79-241 3.96e-16

Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid transport and metabolism]; Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 439849 [Multi-domain]  Cd Length: 341  Bit Score: 78.63  E-value: 3.96e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  79 ERHGwnVTREMLTFTPGIVRGLAFALQCFTAPGDKVMVMPPVY--HPffLVTEHNHREVVYSPLllkDGQYQIDFERFRA 156
Cdd:COG0079   59 EYYG--VPPEQVLVGNGSDELIQLLARAFLGPGDEVLVPEPTFseYP--IAARAAGAEVVEVPL---DEDFSLDLDALLA 131
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 157 DV-KGCKMLILSNPHNPGGRVWTREELAEIAEICfDNQVLVISDEIHADLTLPGYThpTFALVSEkaRRNSLVFMSPSKA 235
Cdd:COG0079  132 AItERTDLVFLCNPNNPTGTLLPREELEALLEAL-PADGLVVVDEAYAEFVPEEDS--ALPLLAR--YPNLVVLRTFSKA 206

                 ....*.
gi 492273001 236 FNMPGL 241
Cdd:COG0079  207 YGLAGL 212
PRK06107 PRK06107
aspartate transaminase;
25-385 1.42e-15

aspartate transaminase;


Pssm-ID: 180403  Cd Length: 402  Bit Score: 77.47  E-value: 1.42e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  25 RWGRsDLLPMWVADMDFRTPPFVIEAIRRRLDHEVLGYTF--ACEAWYTSIINWQKERHGWNVTREMLTFTPGIVRGLAF 102
Cdd:PRK06107  30 AAGR-SIVDLTVGEPDFDTPDHIKQAAVAAIERGETKYTLvnGTPALRKAIIAKLERRNGLHYADNEITVGGGAKQAIFL 108
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 103 ALQCFTAPGDKVMVMPP--VYHPFfLVTEHNHREV-VYSPlllKDGQYQIDFERFRADVK-GCKMLILSNPHNPGGRVWT 178
Cdd:PRK06107 109 ALMATLEAGDEVIIPAPywVSYPD-MVLANDGTPViVACP---EEQGFKLTPEALEAAITpRTRWLILNAPSNPTGAVYS 184
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 179 REELAEIAEICFDN-QVLVISDEIHADLTLPGYTHPTFALVSEKARRNSLVFMSPSKAFNMPGLASSYCIIEDEAIR--H 255
Cdd:PRK06107 185 RAELRALADVLLRHpHVLVLTDDIYDHIRFDDEPTPHLLAAAPELRDRVLVTNGVSKTYAMTGWRIGYAAGPADLIAaiN 264
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 256 RFQTYMEASEFSEGHLFAylgvAAAYSNGTEWLDQALEYIQENIDFTDEYLKThIPAIRMIRPQASYLIFLDCRG-MGV- 333
Cdd:PRK06107 265 KLQSQSSSCPSSISQAAA----AAALNGDQSFVTESVAVYKQRRDYALALLNA-IPGLSCLVPDGAFYLYVNCAGlIGKt 339
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 334 --------SQKELVDFFVDGAHLALNDGAMFGKegEGFMRLNVACPRSVLRQALDQIKEA 385
Cdd:PRK06107 340 tpegkvleTDQDVVLYLLDSAGVAVVQGTAYGL--SPYFRLSIATSLETLEEACARIERA 397
PRK07366 PRK07366
LL-diaminopimelate aminotransferase;
40-382 3.10e-15

LL-diaminopimelate aminotransferase;


Pssm-ID: 180947  Cd Length: 388  Bit Score: 76.64  E-value: 3.10e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  40 DFRTPPFVIEAIRRRL-DHEVLGYTF---------ACEAWYTsiinwqkERHGWNVT--REMLTFTpGIVRGLAFALQCF 107
Cdd:PRK07366  41 DLPAPAHALEAIAQSLhDPSTHGYLLfhgtldfreAAAQWYE-------QRFGLAVDpeTEVLPLI-GSQEGTAHLPLAV 112
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 108 TAPGDKVMVMPPVYhPFFLVTEHNHREVVYSPLLLKDGQYQIDFERFRADV-KGCKMLILSNPHNPGGRVWTREELAEIA 186
Cdd:PRK07366 113 LNPGDFALLLDPGY-PSHAGGVYLAGGQIYPMPLRAENDFLPVFADIPTEVlAQARLMVLSYPHNPTTAIAPLSFFQEAV 191
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 187 EICFDNQVLVISDEIHADLTLPGYTHPTFALVSEKARRNSLVFMSPSKAFNMPGLASSYCIIEDEAIRHRFQTyMEASEF 266
Cdd:PRK07366 192 AFCQQHDLVLVHDFPYVDLVFDGEVEPPSILQADPEKSVSIEFFTLSKSYNMGGFRIGFAIGNAQLIQALRQV-KAVVDF 270
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 267 SEghlfaYLGV----AAAYSNGTEWLDQALEYIQENIDFTDEYLKTH---IPAirmirPQASYLIF--LDCRGMGVSqke 337
Cdd:PRK07366 271 NQ-----YRGIlngaIAALTGPQATVQQTVQIFRQRRDAFINALHQIgwpVPL-----PEATMYVWakLPEPWQGNS--- 337
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*...
gi 492273001 338 lVDF---FVDGAHLALNDGAMFGKEGEGFMRLNVACPRSVLRQALDQI 382
Cdd:PRK07366 338 -VEFctqLVAQTGVAASPGSGFGKSGEGYVRFALVHDPDILEEAVERI 384
PRK07682 PRK07682
aminotransferase;
36-383 4.18e-15

aminotransferase;


Pssm-ID: 181082 [Multi-domain]  Cd Length: 378  Bit Score: 75.93  E-value: 4.18e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  36 VADMDFRTPPFVIEAIRRRLDHevlGYTFaceawYTS---IINWQKERHGWNVTREMLTFTP--------GIVRGLAFAL 104
Cdd:PRK07682  27 VGEPDFVTPWNVREASIRSLEQ---GYTS-----YTAnagLLELRQEIAKYLKKRFAVSYDPndeiivtvGASQALDVAM 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 105 QCFTAPGDKVMVMPPVYhpfflvtehnhreVVYSPLLLKDG------------QYQIDFERFRADV-KGCKMLILSNPHN 171
Cdd:PRK07682  99 RAIINPGDEVLIVEPSF-------------VSYAPLVTLAGgvpvpvattlenEFKVQPAQIEAAItAKTKAILLCSPNN 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 172 PGGRVWTREELAEIAEICFDNQVLVISDEIHADLTLPGyTHPTFALVSEKARRNSLV--FmspSKAFNMPGLASSYCIIE 249
Cdd:PRK07682 166 PTGAVLNKSELEEIAVIVEKHDLIVLSDEIYAELTYDE-AYTSFASIKGMRERTILIsgF---SKGFAMTGWRLGFIAAP 241
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 250 DEAIR-----HRFqTYMEASEFSEghlfayLGVAAAYSNGTEWLDQA-LEYIQENIDFTDEY----LKTHIPAirmirpq 319
Cdd:PRK07682 242 VYFSEamlkiHQY-SMMCAPTMAQ------FAALEALRAGNDDVIRMrDSYRKRRNFFVTSFneigLTCHVPG------- 307
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 492273001 320 ASYLIFLDCRGMGVSQKELVDFFVDGAHLALNDGAMFGKEGEGFMRLNVACPRSVLRQALDQIK 383
Cdd:PRK07682 308 GAFYAFPSISSTGLSSEEFAEQLLLEEKVAVVPGSVFGESGEGFIRCSYATSLEQLQEAMKRMK 371
PTZ00433 PTZ00433
tyrosine aminotransferase; Provisional
38-384 6.23e-15

tyrosine aminotransferase; Provisional


Pssm-ID: 185613  Cd Length: 412  Bit Score: 75.59  E-value: 6.23e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  38 DMDFRTPPFVIEAIRRRLD-HEVLGY--TF----ACEA----WYTSIInwQKERHGWNVTREMLTFTPGIVRGLAFALQC 106
Cdd:PTZ00433  46 DGNLLTPAIQTKALVEAVDsQECNGYppTVgspeAREAvatyWRNSFV--HKESLKSTIKKDNVVLCSGVSHAILMALTA 123
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 107 FTAPGDKVMVMPPVYHPFFLVTEHNHREVVYSpLLLKDGQYQIDFERFRADVKG-CKMLILSNPHNPGGRVWTREELAEI 185
Cdd:PTZ00433 124 LCDEGDNILVPAPGFPHYETVCKAYGIEMRFY-NCRPEKDWEADLDEIRRLVDDrTKALIMTNPSNPCGSNFSRKHVEDI 202
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 186 AEICFDNQVLVISDEIHADLTLPGYTHPTFALVSEKARRnsLVFMSPSKAFNMPGLASSYCIIEDeairhrfqTYMEASE 265
Cdd:PTZ00433 203 IRLCEELRLPLISDEIYAGMVFNGATFTSVADFDTTVPR--VILGGTAKNLVVPGWRLGWLLLVD--------PHGNGGD 272
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 266 FSEGhlFAYLGVAAAYSNG--------------TEWLDQALEYIQENIDFTDEYLKtHIPAIRMIRPQASYLIFLdcrgm 331
Cdd:PTZ00433 273 FLDG--MKRLGMLVCGPCSvvqaalgeallntpQEHLEQIVAKLEEGAMVLYNHIG-ECIGLSPTMPRGSMFLMS----- 344
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492273001 332 GVSQKEL------VDFF---VDGAHLALNDGAMFGKegEGFMRLNVACPRSVLRQALDQIKE 384
Cdd:PTZ00433 345 RLDLEKFrdiksdVEFYeklLEEENVQVLPGEIFHM--PGFTRLTISRPVEVLREAVERIKA 404
ARO8 COG1167
DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain ...
80-385 9.79e-15

DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain [Transcription, Amino acid transport and metabolism]; DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain is part of the Pathway/BioSystem: Lysine biosynthesis


Pssm-ID: 440781 [Multi-domain]  Cd Length: 471  Bit Score: 75.25  E-value: 9.79e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  80 RHGWNVTREMLTFTPGIVRGLAFALQCFTAPGDKVMVMPPVYHPFFLVTEHNHREVVYSPlLLKDGqyqIDFERFRADVK 159
Cdd:COG1167  163 RRGVPASPDQILITSGAQQALDLALRALLRPGDTVAVESPTYPGALAALRAAGLRLVPVP-VDEDG---LDLDALEAALR 238
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 160 --GCKMLILsNP--HNPGGRVWT---REELAEIAEicfDNQVLVISDEIHADLTLPGytHPTFALVSEKARRNSLVFMSP 232
Cdd:COG1167  239 rhRPRAVYV-TPshQNPTGATMSlerRRALLELAR---RHGVPIIEDDYDSELRYDG--RPPPPLAALDAPGRVIYIGSF 312
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 233 SKAFnMPGLASSYcIIEDEAIRHRFQTYMEASEFSeGHLFAYLGVAAAYSNGT--EWLDQALEYIQENIDFTDEYLKTHI 310
Cdd:COG1167  313 SKTL-APGLRLGY-LVAPGRLIERLARLKRATDLG-TSPLTQLALAEFLESGHydRHLRRLRREYRARRDLLLAALARHL 389
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 492273001 311 PA-IRMIRPQASYLIFLDCRGmGVSQKELVDFFVDgAHLALNDGAMF--GKEGEGFMRLNVACP-RSVLRQALDQIKEA 385
Cdd:COG1167  390 PDgLRVTGPPGGLHLWLELPE-GVDAEALAAAALA-RGILVAPGSAFsaDGPPRNGLRLGFGAPsEEELEEALRRLAEL 466
PRK07568 PRK07568
pyridoxal phosphate-dependent aminotransferase;
40-324 1.07e-14

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 181036  Cd Length: 397  Bit Score: 74.89  E-value: 1.07e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  40 DFRTPPFVIEAIRRRlDHEVLGYTFAceAWYTSIIN-WQK--ERHGWNVTREMLTFTPGIVRGLAFALQCFTAPGDKVMV 116
Cdd:PRK07568  41 DIKTPEVFFEAIKNY-DEEVLAYSHS--QGIPELREaFAKyyKKWGIDVEPDEILITNGGSEAILFAMMAICDPGDEILV 117
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 117 MPPVYHPFFLVTEHNHREVVYSPLLLKDGqYQI----DFERFRADvkGCKMLILSNPHNPGGRVWTREELAEIAEICFDN 192
Cdd:PRK07568 118 PEPFYANYNGFATSAGVKIVPVTTKIEEG-FHLpskeEIEKLITP--KTKAILISNPGNPTGVVYTKEELEMLAEIAKKH 194
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 193 QVLVISDEIHADLTLPGYTHPTFaLVSEKARRNSLVFMSPSKAFNMPGlASSYCII-EDEAIrhrfqtYMEASEFSEGHL 271
Cdd:PRK07568 195 DLFLISDEVYREFVYDGLKYTSA-LSLEGLEDRVIIIDSVSKRYSACG-ARIGCLIsKNKEL------IAAAMKLCQARL 266
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 492273001 272 ----FAYLGVAAAYSNGTEWLDQALEYIQENIDFTDEYLKThIPAIRMIRPQ-ASYLI 324
Cdd:PRK07568 267 spptLEQIGAAALLDTPESYFDEVREEYKKRRDILYEELNK-IPGVVCEKPKgAFYII 323
PRK06836 PRK06836
pyridoxal phosphate-dependent aminotransferase;
44-240 2.25e-14

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 180720  Cd Length: 394  Bit Score: 74.07  E-value: 2.25e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  44 PPFVIEAIRRRLDHEV---------LGYTFACEAWYTSIinwqKERHGWNVTREMLTFTPGIVRGLAFALQCFTAPGDKV 114
Cdd:PRK06836  48 PAAVKEALRELAEEEDpglhgympnAGYPEVREAIAESL----NRRFGTPLTADHIVMTCGAAGALNVALKAILNPGDEV 123
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 115 MVMPPvYHP--FFLVTEHNHREVVYSPlllKDGQYQIDFERFRADV-KGCKMLILSNPHNPGGRVWTREELAEIAEIC-- 189
Cdd:PRK06836 124 IVFAP-YFVeyRFYVDNHGGKLVVVPT---DTDTFQPDLDALEAAItPKTKAVIINSPNNPTGVVYSEETLKALAALLee 199
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 492273001 190 ----FDNQVLVISDEIHADLTLPGYTHPT-FALVsekarRNSLVFMSPSKAFNMPG 240
Cdd:PRK06836 200 kskeYGRPIYLISDEPYREIVYDGAEVPYiFKYY-----DNSIVVYSFSKSLSLPG 250
PRK07324 PRK07324
transaminase; Validated
84-384 2.14e-13

transaminase; Validated


Pssm-ID: 235989  Cd Length: 373  Bit Score: 70.74  E-value: 2.14e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  84 NVTREMLTFTPGIVRGLAFALQCFTAPGDKVMVMPPVYHPFFLVTEHNHREVVYSPLLLKDGqYQIDFERFRADVK-GCK 162
Cdd:PRK07324  77 NVKPENILQTNGATGANFLVLYALVEPGDHVISVYPTYQQLYDIPESLGAEVDYWQLKEENG-WLPDLDELRRLVRpNTK 155
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 163 MLILSNPHNPGGRVWTREELAEIAEICFDNQVLVISDEIHADLTLPGYThPTFALVSEKA-RRNSLvfmspSKAFNMPGL 241
Cdd:PRK07324 156 LICINNANNPTGALMDRAYLEEIVEIARSVDAYVLSDEVYRPLDEDGST-PSIADLYEKGiSTNSM-----SKTYSLPGI 229
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 242 ASSYcIIEDEAIRHRFQTYMEASEFSEGHLFAYLGVaAAYSNGTEWLDQALEYIQENIDFTDEYLKTHiPAIRMIRPQA- 320
Cdd:PRK07324 230 RVGW-IAANEEVIDILRKYRDYTMICAGVFDDMLAS-LALEHRDAILERNRKIVRTNLAILDEWVAKE-PRVSYVKPKAv 306
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492273001 321 -SYLIFLD--------C----RGMGVsqkelvdFFVDGAHLalndgamfgkEGEGFMRLNVACPRSVLRQALDQIKE 384
Cdd:PRK07324 307 sTSFVKLDvdmpsedfClkllKETGV-------LLVPGNRF----------DLEGHVRIGYCCDTETLKKGLKKLSE 366
PRK06290 PRK06290
LL-diaminopimelate aminotransferase;
100-240 9.17e-13

LL-diaminopimelate aminotransferase;


Pssm-ID: 235772  Cd Length: 410  Bit Score: 69.30  E-value: 9.17e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 100 LAFALQCFTAPGDKVMVMPPVYHPFFLVTEHNHREVVYSPLLlKDGQYQIDFERFRADVKG-CKMLILSNPHNPGGRVWT 178
Cdd:PRK06290 119 LAMLPSCFINPGDVTLMTVPGYPVTGTHTKYYGGEVYNLPLL-EENNFLPDLDSIPKDIKEkAKLLYLNYPNNPTGAVAT 197
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492273001 179 REELAEIAEICFDNQVLVISDEIHADLTLPGytHPTFALVSEKARRNSLVFMSPSKAFNMPG 240
Cdd:PRK06290 198 KEFYEEVVDFAKENNIIVVQDAAYAALTFDG--KPLSFLSVPGAKEVGVEIHSLSKAYNMTG 257
PLN00175 PLN00175
aminotransferase family protein; Provisional
40-209 1.49e-12

aminotransferase family protein; Provisional


Pssm-ID: 215089 [Multi-domain]  Cd Length: 413  Bit Score: 68.35  E-value: 1.49e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  40 DFRTPPFV----IEAIRRRLDHEVLGYtfACEAWYTSIINWQKERHGWNVTREM-LTFTPGIVRGLAFALQCFTAPGDKV 114
Cdd:PLN00175  65 NFDGPDFVkeaaIQAIRDGKNQYARGF--GVPELNSAIAERFKKDTGLVVDPEKeVTVTSGCTEAIAATILGLINPGDEV 142
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 115 MVMPPVYHPFFLVTEHNHREVvySPLLLKDGQYQIDFERFRADV-KGCKMLILSNPHNPGGRVWTREELAEIAEICFDNQ 193
Cdd:PLN00175 143 ILFAPFYDSYEATLSMAGAKI--KTVTLRPPDFAVPEDELKAAFtSKTRAILINTPHNPTGKMFTREELELIASLCKEND 220
                        170
                 ....*....|....*.
gi 492273001 194 VLVISDEIHADLTLPG 209
Cdd:PLN00175 221 VLAFTDEVYDKLAFEG 236
PRK08960 PRK08960
pyridoxal phosphate-dependent aminotransferase;
30-357 1.84e-12

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 181595  Cd Length: 387  Bit Score: 68.16  E-value: 1.84e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  30 DLLPMWVADMDFRTPPFVIEAIRRRLDHEVLGYTFA--CEAWYTSIINWQKERHGWNVTREMLTFTPGIVRGLAFALQCF 107
Cdd:PRK08960  33 DVIHLEIGEPDFTTAEPIVAAGQAALAAGHTRYTAArgLPALREAIAGFYAQRYGVDVDPERILVTPGGSGALLLASSLL 112
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 108 TAPGDKVMVMPPVY----HpFFLVTEHNHREVVYSPlllkDGQYQI---DFER-FRADVKGckmLILSNPHNPGGRVWTR 179
Cdd:PRK08960 113 VDPGKHWLLADPGYpcnrH-FLRLVEGAAQLVPVGP----DSRYQLtpaLVERhWNADTVG---ALVASPANPTGTLLSR 184
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 180 EELAEIAEICFDNQVLVISDEIHADLTLpGYTHPTFALVSEKArrnsLVFMSPSKAFNMPGLASSYCIIEDEAIRhrfqt 259
Cdd:PRK08960 185 DELAALSQALRARGGHLVVDEIYHGLTY-GVDAASVLEVDDDA----FVLNSFSKYFGMTGWRLGWLVAPPAAVP----- 254
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 260 ymEASEFSEgHLF-------AYLGVAAAYSNGTEWLDQALEYIQENIDFTdeylkthIPAIR------MIRPQASYLIFL 326
Cdd:PRK08960 255 --ELEKLAQ-NLYisastpaQHAALACFEPETLAILEARRAEFARRRDFL-------LPALRelgfgiAVEPQGAFYLYA 324
                        330       340       350
                 ....*....|....*....|....*....|.
gi 492273001 327 DCRGMGVSQKELVDFFVDGAHLALNDGAMFG 357
Cdd:PRK08960 325 DISAFGGDAFAFCRHFLETEHVAFTPGLDFG 355
PRK05942 PRK05942
aspartate aminotransferase; Provisional
30-385 2.75e-12

aspartate aminotransferase; Provisional


Pssm-ID: 180317  Cd Length: 394  Bit Score: 67.44  E-value: 2.75e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  30 DLLPMWVADMDFRTPPFVIEAIRRRLDH-EVLGYT-FACEAWY-TSIINWQKERHG--WNVTREMLTFTpGIVRGLAFAL 104
Cdd:PRK05942  36 DLIDLGMGNPDGAAPQPVIEAAIAALADpQNHGYPpFEGTASFrQAITDWYHRRYGveLDPDSEALPLL-GSKEGLTHLA 114
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 105 QCFTAPGDKVMVMPPVYHPFF---LVTEHNhrevVYSPLLLKDGQYQIDFERFRADV-KGCKMLILSNPHNPGGRVWTRE 180
Cdd:PRK05942 115 LAYVNPGDVVLVPSPAYPAHFrgpLIAGAQ----IYPIILKPENDWLIDLSSIPEEVaQQAKILYFNYPSNPTTATAPRE 190
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 181 ELAEIAEICFDNQVLVISDEIHADLTLPGYtHPTFALVSEKARRNSLVFMSPSKAFNMPGLASSYCIIEDEAIR--HRFQ 258
Cdd:PRK05942 191 FFEEIVAFARKYEIMLVHDLCYAELAFDGY-QPTSLLEIPGAKDIGVEFHTLSKTYNMAGWRVGFVVGNRHIIQglRTLK 269
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 259 TYMEASefseghLFAYLGVAA--AYSNGTEWLDQALEYIQENIDFTDEYLKT---HIPairmiRPQASYLIFLDC-RGMG 332
Cdd:PRK05942 270 TNLDYG------IFSALQKAAetALQLPDSYLQQVQERYRTRRDFLIQGLGElgwNIP-----PTKATMYLWVPCpVGMG 338
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 492273001 333 VSqkelvDFFVD---GAHLALNDGAMFGKEGEGFMRLNV--ACPRsvLRQALDQIKEA 385
Cdd:PRK05942 339 ST-----DFALNvlqKTGVVVTPGNAFGEGGEGYVRISLiaDCDR--LGEALDRLKQA 389
PRK08175 PRK08175
aminotransferase; Validated
72-383 3.41e-12

aminotransferase; Validated


Pssm-ID: 181268 [Multi-domain]  Cd Length: 395  Bit Score: 67.43  E-value: 3.41e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  72 SIINWQKERHGWNVTREM-LTFTPGIVRGLAFALQCFTAPGDKVMVMPPVY--HPF-FLVTEHNHREVVysplLLKDGQY 147
Cdd:PRK08175  75 AISRWYQDRYDVDIDPESeAIVTIGSKEGLAHLMLATLDHGDTVLVPNPSYpiHIYgAVIAGAQVRSVP----LVEGVDF 150
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 148 QIDFER-FRADVKGCKMLILSNPHNPGGRVWTREELAEIAEICFDNQVLVISDEIHADLTLPGYTHPTFALVsEKARRNS 226
Cdd:PRK08175 151 FNELERaIRESYPKPKMMILGFPSNPTAQCVELEFFEKVVALAKRYDVLVVHDLAYADIVYDGWKAPSIMQV-PGAKDVA 229
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 227 LVFMSPSKAFNMPGLASSYCIIEDEAIR--HRFQTYMEASEFS----------EGHLFAYLGVAAAYSNGTEWLDQALEY 294
Cdd:PRK08175 230 VEFFTLSKSYNMAGWRIGFMVGNPELVSalARIKSYHDYGTFTplqvaaiaalEGDQQCVRDIAEQYKRRRDVLVKGLHE 309
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 295 IQENIDftdeylkthipairmiRPQASYLIFLDC----RGMG---VSQKELVDffvdgAHLALNDGAMFGKEGEGFMRLN 367
Cdd:PRK08175 310 AGWMVE----------------MPKASMYVWAKIpepyAAMGsleFAKKLLNE-----AKVCVSPGIGFGDYGDTHVRFA 368
                        330
                 ....*....|....*.
gi 492273001 368 VACPRSVLRQALDQIK 383
Cdd:PRK08175 369 LIENRDRIRQAIRGIK 384
PRK06207 PRK06207
pyridoxal phosphate-dependent aminotransferase;
87-387 4.12e-12

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 235742  Cd Length: 405  Bit Score: 67.10  E-value: 4.12e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  87 REMLTFTPGIVRGLAFALQCFTAPGDKVMVMPPVYHPFFLVTEHNHREVVYSPL--LLKDGQYQIDFERFRADVK-GCKM 163
Cdd:PRK06207 102 ADELIITPGTQGALFLAVAATVARGDKVAIVQPDYFANRKLVEFFEGEMVPVQLdyLSADKRAGLDLDQLEEAFKaGVRV 181
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 164 LILSNPHNPGGRVWTREELAEIAEICFDNQVLVISDEIHADLTLPG--YTHptfaLVSEKARRNSLV-FMSPSKAFNMPG 240
Cdd:PRK06207 182 FLFSNPNNPAGVVYSAEEIAQIAALARRYGATVIVDQLYSRLLYDGtsYTH----LRALPIDPENVItIMGPSKTESLSG 257
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 241 --LASSY---CIIED----EAIrhrfqTYMEASEFSEGHLFAYlgvaaaYSNGTEWLDQALEYIQENIDFTDEYLKTHiP 311
Cdd:PRK06207 258 yrLGVAFgspAIIDRmeklQAI-----VSLRAAGYSQAVLRTW------FSEPDGWMKDRIARHQAIRDDLLRVLRGV-E 325
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 492273001 312 AIRMIRPQASYLIFLDCRGMGVSQKELVDFFVDGAHLALNDGAMFGKEGEGFMRLNVACPRSVLRQALDQIKEAYE 387
Cdd:PRK06207 326 GVFVRAPQAGSYLFPRLPRLAVSLHDFVKILRLQAGVIVTPGTEFSPHTADSIRLNFSQDHAAAVAAAERIAQLIE 401
PRK12414 PRK12414
putative aminotransferase; Provisional
90-292 6.86e-12

putative aminotransferase; Provisional


Pssm-ID: 183514  Cd Length: 384  Bit Score: 66.35  E-value: 6.86e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  90 LTFTPGIVRGLAFALQCFTAPGDKVMVMPPVYHPFFLVTEHNHREVVYSPLLLKDgqYQIDFERFRADVKG-CKMLILSN 168
Cdd:PRK12414  93 VTVIASASEGLYAAISALVHPGDEVIYFEPSFDSYAPIVRLQGATPVAIKLSPED--FRVNWDEVAAAITPrTRMIIVNT 170
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 169 PHNPGGRVWTREELAEIAEICFDNQVLVISDEIHADLTLPGYTHPTFALVSEKARRnSLVFMSPSKAFNMPGLASSYCI- 247
Cdd:PRK12414 171 PHNPSATVFSAADLARLAQLTRNTDIVILSDEVYEHVVFDGARHHSMARHRELAER-SVIVSSFGKSYHVTGWRVGYCLa 249
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 492273001 248 ---IEDEaIRHRFQTYMEASEFSEGHLFA--------YLGVAAAYSNGTEWLDQAL 292
Cdd:PRK12414 250 paeLMDE-IRKVHQFMVFSADTPMQHAFAealaepasYLGLGAFYQRKRDLLAREL 304
PRK06225 PRK06225
pyridoxal phosphate-dependent aminotransferase;
93-373 5.62e-11

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 235749 [Multi-domain]  Cd Length: 380  Bit Score: 63.62  E-value: 5.62e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  93 TPGIVRGLAFALQCFTAPGDKVMVMPPVYHPFFLVTEHNHREVVYSPLLLKDGQYQIDFERFRADVKG-CKMLILSNPHN 171
Cdd:PRK06225  89 TAGATESLYLVMRAFLSPGDNAVTPDPGYLIIDNFASRFGAEVIEVPIYSEECNYKLTPELVKENMDEnTRLIYLIDPLN 168
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 172 PGGRVWTREELAEIAEICFDNQVLVISDEIHADLTlPGYThptfaLVSEKARRNSLVFMSPSKAFNMPGL-----ASSYC 246
Cdd:PRK06225 169 PLGSSYTEEEIKEFAEIARDNDAFLLHDCTYRDFA-REHT-----LAAEYAPEHTVTSYSFSKIFGMAGLrigavVATPD 242
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 247 IIedEAIRHRFQTYMEASefseghLFAYLGVAAAYSNGTEWLDQALE-------YIQENIDFTDEYLkthIPairmIRPQ 319
Cdd:PRK06225 243 LI--EVVKSIVINDLGTN------VIAQEAAIAGLKVKDEWIDRIRRttfknqkLIKEAVDEIEGVF---LP----VYPS 307
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492273001 320 ASYLIFLDCRGMGVSQKELVDFfvdgahlaLNDGAMFGKEGE--------GFMRLNVACPRS 373
Cdd:PRK06225 308 HGNMMVIDISEAGIDPEDLVEY--------LLERKIFVRQGTytskrfgdRYIRVSFSIPRE 361
PRK08068 PRK08068
transaminase; Reviewed
105-382 1.37e-10

transaminase; Reviewed


Pssm-ID: 181219  Cd Length: 389  Bit Score: 62.25  E-value: 1.37e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 105 QCFTAPGDKVMVMPPVYhPFFLVTEHNHREVVYSPLLLKDGQYQIDFERFRADV-KGCKMLILSNPHNPGGRVWTREELA 183
Cdd:PRK08068 112 QCLMNPGDTILVPDPGY-PDYLSGVALARAQFETMPLIAENNFLPDYTKIPEEVaEKAKLMYLNYPNNPTGAVATKAFFE 190
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 184 EIAEICFDNQVLVISD----EIHADltlpGYTHPTFaLVSEKARRNSLVFMSPSKAFNMPGLASSYCIIEDEAIrhrfqt 259
Cdd:PRK08068 191 ETVAFAKKHNIGVVHDfaygAIGFD----GQKPVSF-LQTPGAKDVGIELYTLSKTFNMAGWRVAFAVGNESVI------ 259
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 260 ymEASEFSEGHLFAYL--GVAAAysnGTEWLDQALEYIQENIDFTDEYLKTHIPAIRMI-----RPQASYLIFLDCRGmG 332
Cdd:PRK08068 260 --EAINLLQDHLFVSLfgAIQDA---AIEALLSDQSCVAELVARYESRRNAFISACREIgwevdAPKGSFFAWMPVPK-G 333
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 492273001 333 VSQKELVDFFVDGAHLALNDGAMFGKEGEGFMRLNVACPRSVLRQALDQI 382
Cdd:PRK08068 334 YTSEQFADLLLEKAHVAVAPGNGFGEHGEGYVRVGLLTDEERLREAVERI 383
PRK07337 PRK07337
pyridoxal phosphate-dependent aminotransferase;
17-383 2.79e-10

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 180937  Cd Length: 388  Bit Score: 61.23  E-value: 2.79e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  17 VKYDAVSERWGRsDLLPMWVADMDFRTPPFVIEAIRRRLDHEVLGYTFAC--EAWYTSIINWQKERHGWNVTREMLTFTP 94
Cdd:PRK07337  19 AKEAQALERAGR-DIIHMGIGEPDFTAPEPVVEAAARALRRGVTQYTSALglAPLREAIAAWYARRFGLDVAPERIVVTA 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  95 GIVRGLAFALQCFTAPGDKVMvMP-PVY----HpFFLVTEHNHREVVYSPlllkDGQYQIDFERFRA----DVKGckmLI 165
Cdd:PRK07337  98 GASAALLLACLALVERGDEVL-MPdPSYpcnrH-FVAAAEGRPVLVPSGP----AERFQLTAADVEAawgeRTRG---VL 168
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 166 LSNPHNPGGRVWTREELAEIAEICFDNQVLVISDEIHADLTLPGYTHPTFALVSEKARRNSLvfmspSKAFNMPGLASSY 245
Cdd:PRK07337 169 LASPSNPTGTSIAPDELRRIVEAVRARGGFTIVDEIYQGLSYDAAPVSALSLGDDVITINSF-----SKYFNMTGWRLGW 243
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 246 CIIEDE---AIRHRFQT-YMEASE---------FSEGHLFAYLGVAAAYSNGTEWLDQALeyiqenidftdEYLKTHIPa 312
Cdd:PRK07337 244 LVVPEAlvgTFEKLAQNlFICASAlaqhaalacFEPDTLAIYERRRAEFKRRRDFIVPAL-----------ESLGFKVP- 311
                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 492273001 313 irmIRPQASYLIFLDCRGMGVSQK----ELVDFFVDGAHLALNDGAMFGK-EGEGFMRLNVACPRSVLRQALDQIK 383
Cdd:PRK07337 312 ---VMPDGAFYVYADCRGVAHPAAgdsaALTQAMLHDAGVVLVPGRDFGPhAPRDYIRLSYATSMSRLEEAVARLG 384
PRK08912 PRK08912
aminotransferase;
93-240 6.50e-10

aminotransferase;


Pssm-ID: 181580  Cd Length: 387  Bit Score: 60.37  E-value: 6.50e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  93 TPGIVRGLAFALQCFTAPGDKVMVMPPVYHpfflvtehnhrevVYSPLL-----------LKDGQYQIDFERFRADVKG- 160
Cdd:PRK08912  93 TSGATEALAAALLALVEPGDEVVLFQPLYD-------------AYLPLIrraggvprlvrLEPPHWRLPRAALAAAFSPr 159
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 161 CKMLILSNPHNPGGRVWTREELAEIAEICFDNQVLVISDEIHADLTLPGYTH-PTFALvsEKARRNSLVFMSPSKAFNMP 239
Cdd:PRK08912 160 TKAVLLNNPLNPAGKVFPREELALLAEFCQRHDAVAICDEVWEHVVFDGRRHiPLMTL--PGMRERTVKIGSAGKIFSLT 237

                 .
gi 492273001 240 G 240
Cdd:PRK08912 238 G 238
PLN03026 PLN03026
histidinol-phosphate aminotransferase; Provisional
104-247 1.41e-09

histidinol-phosphate aminotransferase; Provisional


Pssm-ID: 178597  Cd Length: 380  Bit Score: 59.33  E-value: 1.41e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 104 LQCFTAPGDKVMVMPPVYHPFFLVTEHNHREVVYSPLLLkdgQYQIDFERFRADVK--GCKMLILSNPHNPGGRVWTREE 181
Cdd:PLN03026 120 MRCVLDPGDKIIDCPPTFGMYVFDAAVNGAEVIKVPRTP---DFSLDVPRIVEAVEthKPKLLFLTSPNNPDGSIISDDD 196
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492273001 182 LAEIAEIcfdnQVLVISDEIHADL-TLPGYTHptfaLVSEkaRRNSLVFMSPSKAFNMPGLASSYCI 247
Cdd:PLN03026 197 LLKILEL----PILVVLDEAYIEFsTQESRMK----WVKK--YDNLIVLRTFSKRAGLAGLRVGYGA 253
PRK05839 PRK05839
succinyldiaminopimelate transaminase;
86-387 1.25e-08

succinyldiaminopimelate transaminase;


Pssm-ID: 180281  Cd Length: 374  Bit Score: 56.23  E-value: 1.25e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  86 TREMLTFTPgivrglAFALQCFTAPgdkVMVMPpvyHPFFLVTE----HNHREVVYSPLLlKDGQYQIDFERFraDVKGC 161
Cdd:PRK05839  92 TREVLFNFP------QFVLFDKQNP---TIAYP---NPFYQIYEgaaiASRAKVLLMPLT-KENDFTPSLNEK--ELQEV 156
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 162 KMLILSNPHNPGGRVWTREELAEIAEICFDNQVLVISDEIHADLtlpgYTH-PTFAL------VSEKARRNSLVFMSPSK 234
Cdd:PRK05839 157 DLVILNSPNNPTGRTLSLEELIEWVKLALKHDFILINDECYSEI----YENtPPPSLleasilVGNESFKNVLVINSISK 232
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 235 AFNMPGLASSYcIIEDEAIRHRFQTYMeasefseghlfAYLGVAAA----YSNGTEWLDQA-LEYIQE----NIDFTDEY 305
Cdd:PRK05839 233 RSSAPGLRSGF-IAGDASILKKYKAYR-----------TYLGCASPlplqKAAAVAWLDDEhAEFFRNiyakNLKLAREI 300
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 306 LKTHIpairmirPQASYLIFLDCRgmgvSQKELVDFFVDGAHLALNDGAMFGKE--GEGFMRLNVACPRSVLRQALDQIK 383
Cdd:PRK05839 301 LGITI-------PPATFYVWLPVD----NDEEFTKKLYQNEGIKVLPGSFLGRNgiGKGYVRIALVYDTPKLEKALEIIK 369

                 ....
gi 492273001 384 EAYE 387
Cdd:PRK05839 370 TYLE 373
PRK08636 PRK08636
LL-diaminopimelate aminotransferase;
2-384 1.84e-08

LL-diaminopimelate aminotransferase;


Pssm-ID: 236316  Cd Length: 403  Bit Score: 55.87  E-value: 1.84e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001   2 KYNFDEVIERRgtdsvkydaVSERWGRSDLLPMWVADMDFRTPPFVI----EAIRRRLDHevlGYTfACEAWYT---SII 74
Cdd:PRK08636  15 KYVFAEVNELK---------MAARRAGEDIIDFSMGNPDGPTPQHIIdklcESAQKPKTH---GYS-VSKGIYKlrlAIC 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  75 NWQKERHGWNV--TREMLTfTPGIVRGLAFALQCFTAPGDKVMVMPPVY----HPFFLVTEHNHRevvySPLLLKDgQYQ 148
Cdd:PRK08636  82 NWYKRKYNVDLdpETEVVA-TMGSKEGYVHLVQAITNPGDVAIVPDPAYpihsQAFILAGGNVHK----MPLEYNE-DFE 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 149 IDFERFRADVKGC--------KMLILSNPHNPGGRVWTREELAEIAEICFDNQVLVISDEIHADLTLPGYTHPTFALVsE 220
Cdd:PRK08636 156 LDEDQFFENLEKAlresspkpKYVVVNFPHNPTTATVEKSFYERLVALAKKERFYIISDIAYADITFDGYKTPSILEV-E 234
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 221 KARRNSLVFMSPSKAFNMPGLASSYcIIEDEAIRHRFQTYmeASEFSEGhLFAYLGVAAaysngTEWLDQALEYIQENID 300
Cdd:PRK08636 235 GAKDVAVESYTLSKSYNMAGWRVGF-VVGNKKLVGALKKI--KSWLDYG-MFTPIQVAA-----TIALDGDQSCVEEIRE 305
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 301 FTDEYLKTHIPAI-----RMIRPQASYLIFLD----CRGMG---VSQKELVDffvdgAHLALNDGAMFGKEGEGFMRLNV 368
Cdd:PRK08636 306 TYRKRRDVLIESFanagwELQKPRASMFVWAKipepARHLGsleFSKQLLTE-----AKVAVSPGIGFGEYGDEYVRIAL 380
                        410
                 ....*....|....*.
gi 492273001 369 ACPRSVLRQALDQIKE 384
Cdd:PRK08636 381 IENENRIRQAARNIKK 396
avtA PRK09440
valine--pyruvate transaminase; Provisional
78-253 1.26e-07

valine--pyruvate transaminase; Provisional


Pssm-ID: 236517  Cd Length: 416  Bit Score: 53.32  E-value: 1.26e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  78 KERHGWNVTREMLTFTPGIVRGLAFALQCFTAPGD-----KVMV-MPPVYHPFFLVTEHNHREVVYSPL--LLKDGQ--Y 147
Cdd:PRK09440  88 NERYGWNISPQNIALTNGSQSAFFYLFNLFAGRRAdgslkKILFpLAPEYIGYADAGLEEDLFVSYRPNieLLPEGQfkY 167
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 148 QIDFERFRADvKGCKMLILSNPHNPGGRVWTREELAEIAEICFDNQVLVISDEihadltlpGYTHPTFALVSEKAR---- 223
Cdd:PRK09440 168 HVDFEHLHID-EDTGAICVSRPTNPTGNVLTDEELEKLDALARQHNIPLLIDN--------AYGPPFPGIIFSEATplwn 238
                        170       180       190
                 ....*....|....*....|....*....|..
gi 492273001 224 RNSLVFMSPSKAfnmpGLASSYC--IIEDEAI 253
Cdd:PRK09440 239 PNIILCMSLSKL----GLPGVRCgiVIADEEI 266
PRK05957 PRK05957
pyridoxal phosphate-dependent aminotransferase;
86-248 1.29e-07

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 235654  Cd Length: 389  Bit Score: 53.15  E-value: 1.29e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  86 TREMLTFTPGIVRGLAFALQCFTAPGDKVMVMPPVY--HpFFLVTEHNHREVvyspLLLKDGQYQIDFERFRADVKGCKM 163
Cdd:PRK05957  88 NEQAIVVTAGSNMAFMNAILAITDPGDEIILNTPYYfnH-EMAITMAGCQPI----LVPTDDNYQLQPEAIEQAITPKTR 162
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 164 LILS-NPHNPGGRVWTREELAEIAEICFDNQVLVISDEIHADLTLPGYTH--PTfALVSEKARRNSLvfMSPSKAFNMPG 240
Cdd:PRK05957 163 AIVTiSPNNPTGVVYPEALLRAVNQICAEHGIYHISDEAYEYFTYDGVKHfsPG-SIPGSGNHTISL--YSLSKAYGFAS 239

                 ....*...
gi 492273001 241 LASSYCII 248
Cdd:PRK05957 240 WRIGYMVI 247
PLN02656 PLN02656
tyrosine transaminase
93-209 2.11e-07

tyrosine transaminase


Pssm-ID: 178262 [Multi-domain]  Cd Length: 409  Bit Score: 52.62  E-value: 2.11e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  93 TPGIVRGLAFALQCFTAPGDKVMVMPPVYHPFFLVTEHNHREVVYSPLLLKDGqYQIDFERFR--ADVKGCKMLILsNPH 170
Cdd:PLN02656 102 TSGCTQAIDVALSMLARPGANILLPRPGFPIYELCAAFRHLEVRYVDLLPEKG-WEVDLDAVEalADQNTVALVII-NPG 179
                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 492273001 171 NPGGRVWTREELAEIAEICFDNQVLVISDEIHADLTLPG 209
Cdd:PLN02656 180 NPCGNVYSYQHLKKIAETAEKLKILVIADEVYGHLAFGS 218
PRK09147 PRK09147
succinyldiaminopimelate transaminase; Provisional
42-260 7.90e-07

succinyldiaminopimelate transaminase; Provisional


Pssm-ID: 236393  Cd Length: 396  Bit Score: 50.64  E-value: 7.90e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  42 RTPPFVIEAIRRRLDHeVLGY--TFACEAWYTSIINWQKERHGW------------NVTREMLtftpgivrgLAFAlQCF 107
Cdd:PRK09147  42 PTPAFIKDALAANLDG-LASYptTAGLPALREAIAAWLERRYGLpaldpatqvlpvNGSREAL---------FAFA-QTV 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 108 TAPGDK--VMVMP-PVYH------------PFFL-VTEHNHrevvysplllkdgqYQIDFERFRADV-KGCKMLILSNPH 170
Cdd:PRK09147 111 IDRDGPgpLVVCPnPFYQiyegaallagaePYFLnCDPANN--------------FAPDFDAVPAEVwARTQLLFVCSPG 176
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 171 NPGGRVWTREELAEIAEICfDNQVLVI-SDEIHADLTLPGYTHPTFALvsEKAR-------RNSLVFMSPSKAFNMPGLA 242
Cdd:PRK09147 177 NPTGAVLPLDDWKKLFALS-DRYGFVIaSDECYSEIYFDEAAPPLGLL--EAAAelgrddfKRLVVFHSLSKRSNVPGLR 253
                        250       260
                 ....*....|....*....|.
gi 492273001 243 SSYcIIEDEAIRHRF---QTY 260
Cdd:PRK09147 254 SGF-VAGDAALLKKFllyRTY 273
PLN00145 PLN00145
tyrosine/nicotianamine aminotransferase; Provisional
93-206 1.63e-06

tyrosine/nicotianamine aminotransferase; Provisional


Pssm-ID: 215074 [Multi-domain]  Cd Length: 430  Bit Score: 49.77  E-value: 1.63e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  93 TPGIVRGLAFALQCFTAPGDKVMVMPPVYHPFFLVTEHNHREVVYSPLLLKDGqYQIDFERFR--ADVKGCKMLILsNPH 170
Cdd:PLN00145 123 TAGCAQAIEIIMSVLAQPGANILLPRPGYPLYEARAVFSGLEVRHFDLLPERG-WEVDLEGVEalADENTVAMVII-NPN 200
                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 492273001 171 NPGGRVWTREELAEIAEICFDNQVLVISDEIHADLT 206
Cdd:PLN00145 201 NPCGSVYSYEHLAKIAETARKLGILVIADEVYDHLT 236
PRK08354 PRK08354
putative aminotransferase; Provisional
88-272 2.15e-06

putative aminotransferase; Provisional


Pssm-ID: 169399  Cd Length: 311  Bit Score: 48.96  E-value: 2.15e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  88 EMLTFTPGIVRglAFALQCFTAPGDKVMVMP-PVYHPFFLVTEHNHREVVYSPLllkdgqyqiDFERFRADVKGCKMLIL 166
Cdd:PRK08354  55 EPIVITAGITE--ALYLIGILALRDRKVIIPrHTYGEYERVARFFAARIIKGPN---------DPEKLEELVERNSVVFF 123
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 167 SNPHNPGGRVWTREELAEIAEICFDNQVLVISDEIHADLtLPGYTHPTFalvsekarRNSLVFMSPSKAFNMPGLASSYC 246
Cdd:PRK08354 124 CNPNNPDGKFYNFKELKPLLDAVEDRNALLILDEAFIDF-VKKPESPEG--------ENIIKLRTFTKSYGLPGIRVGYV 194
                        170       180
                 ....*....|....*....|....*.
gi 492273001 247 IIEDEAIRhrfQTYMEASEFSEGHLF 272
Cdd:PRK08354 195 KGFEEAFR---SVRMPWSIGSTGYAF 217
PLN00143 PLN00143
tyrosine/nicotianamine aminotransferase; Provisional
83-205 5.15e-06

tyrosine/nicotianamine aminotransferase; Provisional


Pssm-ID: 165711 [Multi-domain]  Cd Length: 409  Bit Score: 48.08  E-value: 5.15e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  83 WNVTREMLTFTPGIVRGLAFALQCFTAPGDKVMVMPPVYHPFFLVTEHNHREVVYSPLLLKDGqYQIDFERFRA--DVKG 160
Cdd:PLN00143  93 YQLSPDDVYLTLGCKHAAEIIIKVLARPEANILLPRPGFPDVETYAIFHHLEIRHFDLLPEKG-WEVDLDAVEAiaDENT 171
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 492273001 161 CKMLILsNPHNPGGRVWTREELAEIAEICFDNQVLVISDEIHADL 205
Cdd:PLN00143 172 IAMVII-NPGNPCGSVYSYEHLNKIAETARKLGILVIADEVYGHI 215
PRK07550 PRK07550
aminotransferase;
79-369 5.91e-06

aminotransferase;


Pssm-ID: 181026 [Multi-domain]  Cd Length: 386  Bit Score: 48.03  E-value: 5.91e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  79 ERHGWNVTREMLTFTPGIVRGLAFALQCFTAPGDKVMVMPPVYhpfFlvtehNHR--------EVVYSPLLLKDGqYQID 150
Cdd:PRK07550  82 RLYGAAISPEQVHITSGCNQAFWAAMVTLAGAGDEVILPLPWY---F-----NHKmwldmlgiRPVYLPCDEGPG-LLPD 152
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 151 FERFRADVK-GCKMLILSNPHNPGGRVWTREELAEIAEICFDNQVLVISDEIHADLTlPGYTHPtFALVSEKARRNSLV- 228
Cdd:PRK07550 153 PAAAEALITpRTRAIALVTPNNPTGVVYPPELLHELYDLARRHGIALILDETYRDFD-SGGGAP-HDLFADPDWDDTLVh 230
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 229 FMSPSKAFNMPG-----LASSyciieDEAIRH--RFQTYME--ASEfseghlFAYLGVAAAYSNGTEWLDQ-ALEyiqen 298
Cdd:PRK07550 231 LYSFSKSYALTGhrvgaVVAS-----PARIAEieKFMDTVAicAPR------IGQIAVAWGLPNLADWRAGnRAE----- 294
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 492273001 299 IDFTDEYLKTHIPAIRMIRPQAS--YLIFLDCRGMGVSQKELVDFFVDGAHLALNDGAMFGKEGEGFMRLNVA 369
Cdd:PRK07550 295 IARRRDAFRAVFARLPGWELLASgaYFAYVRHPFPDRPSREVARRLAKEAGILCLPGTMFGPGQEGYLRLAFA 367
PRK09148 PRK09148
LL-diaminopimelate aminotransferase;
93-240 6.79e-06

LL-diaminopimelate aminotransferase;


Pssm-ID: 181674 [Multi-domain]  Cd Length: 405  Bit Score: 47.75  E-value: 6.79e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  93 TPGIVRGLAFALQCFTAPGDKVMVMPPVY--HPF-FLVTEHNHREVVYSPlllkDGQYQIDFER-FRADVKGCKMLILSN 168
Cdd:PRK09148  98 TLGSKEGFANMAQAITAPGDVILCPNPSYpiHAFgFIMAGGVIRSVPAEP----DEEFFPALERaVRHSIPKPIALIVNY 173
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 492273001 169 PHNPGGRVWTREELAEIAEICFDNQVLVISDEIHADLTLPGYTHPTFALVsEKARRNSLVFMSPSKAFNMPG 240
Cdd:PRK09148 174 PSNPTAYVADLDFYKDVVAFAKKHDIIILSDLAYSEIYFDGNPPPSVLQV-PGAKDVTVEFTSMSKTFSMAG 244
PLN02187 PLN02187
rooty/superroot1
85-250 9.55e-06

rooty/superroot1


Pssm-ID: 215119 [Multi-domain]  Cd Length: 462  Bit Score: 47.41  E-value: 9.55e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  85 VTREMLTFTPGIVRGLAFALQCFTAPGDKVMVMPPVYhpfflvtEHNHREVVYSPL------LLKDGQYQIDFERFRA-- 156
Cdd:PLN02187 129 LTPEDIFLTAGCNQGIEIVFESLARPNANILLPRPGF-------PHYDARAAYSGLevrkfdLLPEKEWEIDLEGIEAia 201
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 157 DVKGCKMLILsNPHNPGGRVWTREELAEIAEICFDNQVLVISDEIHaDLTLPGyTHPTFALVSEKARRNSLVFMSPSKAF 236
Cdd:PLN02187 202 DENTVAMVVI-NPNNPCGNVYSHDHLKKVAETARKLGIMVISDEVY-DRTIFG-DNPFVSMGKFASIVPVLTLAGISKGW 278
                        170
                 ....*....|....
gi 492273001 237 NMPGLASSYCIIED 250
Cdd:PLN02187 279 VVPGWKIGWIALND 292
PRK13355 PRK13355
bifunctional HTH-domain containing protein/aminotransferase; Provisional
37-216 1.34e-05

bifunctional HTH-domain containing protein/aminotransferase; Provisional


Pssm-ID: 237361 [Multi-domain]  Cd Length: 517  Bit Score: 47.04  E-value: 1.34e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  37 ADMDFRTPPFVIEAIRRRLdHEVLGYT-----FACEawyTSIINWQKERHGWNVTREMLTFTPGIVRGLAFALQCFTAPG 111
Cdd:PRK13355 157 APFGFRTPDEVVYDMAQQL-TDTEGYSdskglFSAR---KAIMQYAQLKGLPNVDVDDIYTGNGVSELINLSMSALLDDG 232
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 112 DKVMVMPPVYhPFFL--VTEHNHREVVYspLLLKDGQYQIDFERFRADVKG-CKMLILSNPHNPGGRVWTREELAEIAEI 188
Cdd:PRK13355 233 DEVLIPSPDY-PLWTacVNLAGGTAVHY--RCDEQSEWYPDIDDIRSKITSrTKAIVIINPNNPTGALYPREVLQQIVDI 309
                        170       180
                 ....*....|....*....|....*...
gi 492273001 189 CFDNQVLVISDEIHADLTLPGYTHPTFA 216
Cdd:PRK13355 310 AREHQLIIFSDEIYDRLVMDGLEHTSIA 337
PRK05166 PRK05166
histidinol-phosphate transaminase;
159-254 1.34e-05

histidinol-phosphate transaminase;


Pssm-ID: 179950  Cd Length: 371  Bit Score: 46.67  E-value: 1.34e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 159 KGCKMLILSNPHNPGGRVWTREELAEIAEICFDNQVLVIsDEIHADltlpgYTH----PTFALVSEKARRNSLVFMSPSK 234
Cdd:PRK05166 158 RAPRMLMFSNPSNPVGSWLTADQLARVLDATPPETLIVV-DEAYAE-----YAAgddyPSALTLLKARGLPWIVLRTFSK 231
                         90       100
                 ....*....|....*....|
gi 492273001 235 AFNMPGLASSYCIIEDEAIR 254
Cdd:PRK05166 232 AYGLAGLRVGYGLVSDPELV 251
PTZ00377 PTZ00377
alanine aminotransferase; Provisional
110-202 4.57e-05

alanine aminotransferase; Provisional


Pssm-ID: 240391 [Multi-domain]  Cd Length: 481  Bit Score: 45.34  E-value: 4.57e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 110 PGDKVMVMPPVYhPFF--LVTEHNHREVVYspLLLKDGQYQIDFERFRADVKGCKM-------LILSNPHNPGGRVWTRE 180
Cdd:PTZ00377 162 PSDGVMIPIPQY-PLYsaAITLLGGKQVPY--YLDEEKGWSLDQEELEEAYEQAVRngitpraLVVINPGNPTGQVLTRD 238
                         90       100
                 ....*....|....*....|..
gi 492273001 181 ELAEIAEICFDNQVLVISDEIH 202
Cdd:PTZ00377 239 VMEEIIKFCYEKGIVLMADEVY 260
PRK06855 PRK06855
pyridoxal phosphate-dependent aminotransferase;
163-218 1.66e-04

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 180734  Cd Length: 433  Bit Score: 43.40  E-value: 1.66e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 492273001 163 MLIlsNPHNPGGRVWTREELAEIAEICFDNQVLVISDEIHADLTLPGYTHPTFALV 218
Cdd:PRK06855 176 LLI--NPDNPTGAVYPKEILREIVDIAREYDLFIICDEIYNNIVYNGKKTVPLSEV 229
PRK08637 PRK08637
hypothetical protein; Provisional
93-199 6.40e-04

hypothetical protein; Provisional


Pssm-ID: 181512  Cd Length: 388  Bit Score: 41.48  E-value: 6.40e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  93 TPGIVRGLAFALQCFTAPGDKVMVMPPVYHPFFLVTEHNHR-EVVYSPLLLKDGQYqiDFERFRADV-----KGCKMLIL 166
Cdd:PRK08637  75 TNALTHGLSLVADLFVDQGDTVLLPDHNWGNYKLTFNTRRGaEIVTYPIFDEDGGF--DTDALKEALqaaynKGKVIVIL 152
                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 492273001 167 SNPHNPGGRVWTREELAEIAEICFD-----NQVLVISD 199
Cdd:PRK08637 153 NFPNNPTGYTPTEKEATAIVEAIKEladagTKVVAVVD 190
PLN02450 PLN02450
1-aminocyclopropane-1-carboxylate synthase
106-240 8.74e-04

1-aminocyclopropane-1-carboxylate synthase


Pssm-ID: 178069 [Multi-domain]  Cd Length: 468  Bit Score: 41.28  E-value: 8.74e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 106 CFTAPGDKVMVmPPVYHPFF-----------LVTEH----NHREVVYSPLllkDGQYQiDFERFRADVKGckmLILSNPH 170
Cdd:PLN02450 130 CLAEPGDAFLL-PTPYYPGFdrdlkwrtgveIVPIHcsssNGFQITESAL---EEAYQ-QAQKLNLKVKG---VLITNPS 201
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001 171 NPGGRVWTREELAEIAEICFDNQVLVISDEIHADLTlpgYTHPTFALVSEKARRNSL----------VFMSPSKAFNMPG 240
Cdd:PLN02450 202 NPLGTTTTRTELNLLVDFITAKNIHLISDEIYSGTV---FDSPGFVSVMEVLKDRKLentdvsnrvhIVYSLSKDLGLPG 278
PLN02368 PLN02368
alanine transaminase
79-202 6.72e-03

alanine transaminase


Pssm-ID: 177996 [Multi-domain]  Cd Length: 407  Bit Score: 38.24  E-value: 6.72e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492273001  79 ERHGWNVTREMLTFTPGIVRGLAFALQCFT-APGDKVMVMPPVYhPFFLVTEHNHREVVYSPLLLKDGQYQIDFERFRAD 157
Cdd:PLN02368 122 RRDGYPSDPELIFLTDGASKGVMQILNAVIrGEKDGVLVPVPQY-PLYSATISLLGGTLVPYYLEESENWGLDVNNLRQS 200
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 492273001 158 V-----KG--CKMLILSNPHNPGGRVWTREELAEIAEICFDNQVLVISDEIH 202
Cdd:PLN02368 201 VaqarsKGitVRAMVIINPGNPTGQCLSEANLREILKFCYQERLVLLGDEVY 252
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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