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Conserved domains on  [gi|490520343|ref|WP_004385817|]
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MULTISPECIES: EnvZ/OmpR regulon moderator MzrA [Cronobacter]

Protein Classification

EnvZ/OmpR regulon moderator MzrA( domain architecture ID 10013585)

EnvZ/OmpR regulon moderator MzrA modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK10629 PRK10629
EnvZ/OmpR regulon moderator MzrA;
1-127 6.25e-55

EnvZ/OmpR regulon moderator MzrA;


:

Pssm-ID: 236728  Cd Length: 127  Bit Score: 167.49  E-value: 6.25e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520343   1 MAFTRALSRRLTLMLSAGALLAAMLLCWAALQKHETTLEIRAVSQGATIPDGFSVWHHLDANGIRFKSITPQDDILLIKF 80
Cdd:PRK10629   1 MINPRMSLRQLAWLGAVLLLLAALLLAWSALRQQESTLAIRAVHQGASLPDGFYVYQHLDANGIHIKSITPENDSLLIRF 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 490520343  81 DTSDQSEAARKVLYRSLPRGFVIAQQEEKSLTPAWLTRLRHDIQRLG 127
Cdd:PRK10629  81 DSPEQSAAAKEVLDRTLPHGYIIAQQDDNSQAMQWLTRLRDNSHRLG 127
 
Name Accession Description Interval E-value
PRK10629 PRK10629
EnvZ/OmpR regulon moderator MzrA;
1-127 6.25e-55

EnvZ/OmpR regulon moderator MzrA;


Pssm-ID: 236728  Cd Length: 127  Bit Score: 167.49  E-value: 6.25e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520343   1 MAFTRALSRRLTLMLSAGALLAAMLLCWAALQKHETTLEIRAVSQGATIPDGFSVWHHLDANGIRFKSITPQDDILLIKF 80
Cdd:PRK10629   1 MINPRMSLRQLAWLGAVLLLLAALLLAWSALRQQESTLAIRAVHQGASLPDGFYVYQHLDANGIHIKSITPENDSLLIRF 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 490520343  81 DTSDQSEAARKVLYRSLPRGFVIAQQEEKSLTPAWLTRLRHDIQRLG 127
Cdd:PRK10629  81 DSPEQSAAAKEVLDRTLPHGYIIAQQDDNSQAMQWLTRLRDNSHRLG 127
SecD-TM1 pfam13721
SecD export protein N-terminal TM region; This domain appears to be the fist transmembrane ...
 37-105 4.75e-19

SecD export protein N-terminal TM region; This domain appears to be the fist transmembrane region of the SecD export protein. SecD is directly involved in protein secretion and important for the release of proteins that have been translocated across the cytoplasmic membrane.


Pssm-ID: 463968 [Multi-domain]  Cd Length: 103  Bit Score: 75.63  E-value: 4.75e-19
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 490520343   37 TLEIRAVSQGATIPDGF--SVWHHLDANGIRFKSITPQDDILLIKFDTSDQSEAARKVLYRSLPRGFVIAQ 105
Cdd:pfam13721  33 AVQISAARGGAKVDEATldRVEQALKAAGIPVKSIELEGDSLLVRFDSTDDQLKAKDVLQRALGDDYVVAL 103
 
Name Accession Description Interval E-value
PRK10629 PRK10629
EnvZ/OmpR regulon moderator MzrA;
1-127 6.25e-55

EnvZ/OmpR regulon moderator MzrA;


Pssm-ID: 236728  Cd Length: 127  Bit Score: 167.49  E-value: 6.25e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520343   1 MAFTRALSRRLTLMLSAGALLAAMLLCWAALQKHETTLEIRAVSQGATIPDGFSVWHHLDANGIRFKSITPQDDILLIKF 80
Cdd:PRK10629   1 MINPRMSLRQLAWLGAVLLLLAALLLAWSALRQQESTLAIRAVHQGASLPDGFYVYQHLDANGIHIKSITPENDSLLIRF 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 490520343  81 DTSDQSEAARKVLYRSLPRGFVIAQQEEKSLTPAWLTRLRHDIQRLG 127
Cdd:PRK10629  81 DSPEQSAAAKEVLDRTLPHGYIIAQQDDNSQAMQWLTRLRDNSHRLG 127
SecD-TM1 pfam13721
SecD export protein N-terminal TM region; This domain appears to be the fist transmembrane ...
 37-105 4.75e-19

SecD export protein N-terminal TM region; This domain appears to be the fist transmembrane region of the SecD export protein. SecD is directly involved in protein secretion and important for the release of proteins that have been translocated across the cytoplasmic membrane.


Pssm-ID: 463968 [Multi-domain]  Cd Length: 103  Bit Score: 75.63  E-value: 4.75e-19
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 490520343   37 TLEIRAVSQGATIPDGF--SVWHHLDANGIRFKSITPQDDILLIKFDTSDQSEAARKVLYRSLPRGFVIAQ 105
Cdd:pfam13721  33 AVQISAARGGAKVDEATldRVEQALKAAGIPVKSIELEGDSLLVRFDSTDDQLKAKDVLQRALGDDYVVAL 103
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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