MULTISPECIES: elongation factor P [Corynebacterium]
elongation factor P( domain architecture ID 11415475)
elongation factor P (EF-P) is an essential protein that stimulates ribosomal peptidyltransferase activity
List of domain hits
Name | Accession | Description | Interval | E-value | ||||
Efp | COG0231 | Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) [Translation, ... |
1-186 | 6.83e-108 | ||||
Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) [Translation, ribosomal structure and biogenesis]; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) is part of the Pathway/BioSystem: Translation factors : Pssm-ID: 440001 [Multi-domain] Cd Length: 186 Bit Score: 306.18 E-value: 6.83e-108
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Name | Accession | Description | Interval | E-value | ||||
Efp | COG0231 | Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) [Translation, ... |
1-186 | 6.83e-108 | ||||
Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) [Translation, ribosomal structure and biogenesis]; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) is part of the Pathway/BioSystem: Translation factors Pssm-ID: 440001 [Multi-domain] Cd Length: 186 Bit Score: 306.18 E-value: 6.83e-108
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PRK00529 | PRK00529 | elongation factor P; Validated |
1-186 | 1.81e-106 | ||||
elongation factor P; Validated Pssm-ID: 234788 [Multi-domain] Cd Length: 186 Bit Score: 302.74 E-value: 1.81e-106
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efp | TIGR00038 | translation elongation factor P; function: involved in peptide bond synthesis. stimulate ... |
2-185 | 1.47e-100 | ||||
translation elongation factor P; function: involved in peptide bond synthesis. stimulate efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (by similarity). The trusted cutoff of this model is set high enough to exclude members of TIGR02178, an EFP-like protein of certain Gammaproteobacteria. [Protein synthesis, Translation factors] Pssm-ID: 272867 [Multi-domain] Cd Length: 184 Bit Score: 287.82 E-value: 1.47e-100
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Elong-fact-P_C | pfam09285 | Elongation factor P, C-terminal; Members of this family of nucleic acid binding domains are ... |
129-184 | 5.35e-29 | ||||
Elongation factor P, C-terminal; Members of this family of nucleic acid binding domains are predominantly found in elongation factor P, where they adopt an OB-fold, with five beta-strands forming a beta-barrel in a Greek-key topology. Pssm-ID: 430503 [Multi-domain] Cd Length: 56 Bit Score: 101.69 E-value: 5.35e-29
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S1_EF-P_repeat_2 | cd05794 | S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. ... |
129-184 | 8.05e-26 | ||||
S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with N-formylmethionyl-tRNA and puromycine in vitro. EF-P binds to both the 30S and 50S ribosomal subunits. EF-P binds near the streptomycine binding site of the 16S rRNA in the 30S subunit. EF-P interacts with domains 2 and 5 of the 23S rRNA. The L16 ribosomal protein of the 50S or its N-terminal fragment are required for EF-P mediated peptide bond synthesis, whereas L11, L15, and L7/L12 are not required in this reaction, suggesting that EF-P may function at a different ribosomal site than most other translation factors. EF-P is essential for cell viability and is required for protein synthesis. EF-P is mainly present in bacteria. The EF-P homologs in archaea and eukaryotes are the initiation factors aIF5A and eIF5A, respectively. EF-P has 3 domains (domains I, II, and III). Domains II and III are S1-like domains. This CD includes domain III (the second S1 domain of EF_P). Domains II and III of have structural homology to the eIF5A domain C, suggesting that domains II and III evolved by duplication. Pssm-ID: 240220 [Multi-domain] Cd Length: 56 Bit Score: 93.74 E-value: 8.05e-26
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Elong-fact-P_C | smart00841 | Elongation factor P, C-terminal; These nucleic acid binding domains are predominantly found in ... |
129-184 | 1.13e-25 | ||||
Elongation factor P, C-terminal; These nucleic acid binding domains are predominantly found in elongation factor P, where they adopt an OB-fold, with five beta-strands forming a beta-barrel in a Greek-key topology. Pssm-ID: 214849 [Multi-domain] Cd Length: 57 Bit Score: 93.29 E-value: 1.13e-25
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Name | Accession | Description | Interval | E-value | ||||
Efp | COG0231 | Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) [Translation, ... |
1-186 | 6.83e-108 | ||||
Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) [Translation, ribosomal structure and biogenesis]; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) is part of the Pathway/BioSystem: Translation factors Pssm-ID: 440001 [Multi-domain] Cd Length: 186 Bit Score: 306.18 E-value: 6.83e-108
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PRK00529 | PRK00529 | elongation factor P; Validated |
1-186 | 1.81e-106 | ||||
elongation factor P; Validated Pssm-ID: 234788 [Multi-domain] Cd Length: 186 Bit Score: 302.74 E-value: 1.81e-106
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efp | TIGR00038 | translation elongation factor P; function: involved in peptide bond synthesis. stimulate ... |
2-185 | 1.47e-100 | ||||
translation elongation factor P; function: involved in peptide bond synthesis. stimulate efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (by similarity). The trusted cutoff of this model is set high enough to exclude members of TIGR02178, an EFP-like protein of certain Gammaproteobacteria. [Protein synthesis, Translation factors] Pssm-ID: 272867 [Multi-domain] Cd Length: 184 Bit Score: 287.82 E-value: 1.47e-100
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PRK14578 | PRK14578 | elongation factor P; Provisional |
1-184 | 9.40e-44 | ||||
elongation factor P; Provisional Pssm-ID: 173042 [Multi-domain] Cd Length: 187 Bit Score: 143.82 E-value: 9.40e-44
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PRK04542 | PRK04542 | elongation factor P; Provisional |
1-184 | 1.09e-39 | ||||
elongation factor P; Provisional Pssm-ID: 179863 [Multi-domain] Cd Length: 189 Bit Score: 133.55 E-value: 1.09e-39
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PRK12426 | PRK12426 | elongation factor P; Provisional |
1-185 | 3.08e-32 | ||||
elongation factor P; Provisional Pssm-ID: 183522 [Multi-domain] Cd Length: 185 Bit Score: 114.17 E-value: 3.08e-32
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Elong-fact-P_C | pfam09285 | Elongation factor P, C-terminal; Members of this family of nucleic acid binding domains are ... |
129-184 | 5.35e-29 | ||||
Elongation factor P, C-terminal; Members of this family of nucleic acid binding domains are predominantly found in elongation factor P, where they adopt an OB-fold, with five beta-strands forming a beta-barrel in a Greek-key topology. Pssm-ID: 430503 [Multi-domain] Cd Length: 56 Bit Score: 101.69 E-value: 5.35e-29
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S1_EF-P_repeat_2 | cd05794 | S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. ... |
129-184 | 8.05e-26 | ||||
S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with N-formylmethionyl-tRNA and puromycine in vitro. EF-P binds to both the 30S and 50S ribosomal subunits. EF-P binds near the streptomycine binding site of the 16S rRNA in the 30S subunit. EF-P interacts with domains 2 and 5 of the 23S rRNA. The L16 ribosomal protein of the 50S or its N-terminal fragment are required for EF-P mediated peptide bond synthesis, whereas L11, L15, and L7/L12 are not required in this reaction, suggesting that EF-P may function at a different ribosomal site than most other translation factors. EF-P is essential for cell viability and is required for protein synthesis. EF-P is mainly present in bacteria. The EF-P homologs in archaea and eukaryotes are the initiation factors aIF5A and eIF5A, respectively. EF-P has 3 domains (domains I, II, and III). Domains II and III are S1-like domains. This CD includes domain III (the second S1 domain of EF_P). Domains II and III of have structural homology to the eIF5A domain C, suggesting that domains II and III evolved by duplication. Pssm-ID: 240220 [Multi-domain] Cd Length: 56 Bit Score: 93.74 E-value: 8.05e-26
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Elong-fact-P_C | smart00841 | Elongation factor P, C-terminal; These nucleic acid binding domains are predominantly found in ... |
129-184 | 1.13e-25 | ||||
Elongation factor P, C-terminal; These nucleic acid binding domains are predominantly found in elongation factor P, where they adopt an OB-fold, with five beta-strands forming a beta-barrel in a Greek-key topology. Pssm-ID: 214849 [Multi-domain] Cd Length: 57 Bit Score: 93.29 E-value: 1.13e-25
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S1_EF-P_repeat_1 | cd04470 | S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. ... |
66-126 | 6.70e-25 | ||||
S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with N-formylmethionyl-tRNA and puromycine in vitro. EF-P binds to both the 30S and 50S ribosomal subunits. EF-P binds near the streptomycine binding site of the 16S rRNA in the 30S subunit. EF-P interacts with domains 2 and 5 of the 23S rRNA. The L16 ribosomal protein of the 50S or its N-terminal fragment are required for EF-P mediated peptide bond synthesis, whereas L11, L15, and L7/L12 are not required in this reaction, suggesting that EF-P may function at a different ribosomal site than most other translation factors. EF-P is essential for cell viability and is required for protein synthesis. EF-P is mainly present in bacteria. The EF-P homologs in archaea and eukaryotes are the initiation factors aIF5A and eIF5A, respectively. EF-P has 3 domains (domains I, II, and III). Domains II and III are S1-like domains. This CD includes domain II (the first S1 domain of EF_P). Domains II and III have structural homology to the eIF5A domain C, suggesting that domains II and III evolved by duplication. Pssm-ID: 239916 [Multi-domain] Cd Length: 61 Bit Score: 91.37 E-value: 6.70e-25
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EFP | pfam01132 | Elongation factor P (EF-P) OB domain; |
68-121 | 4.72e-23 | ||||
Elongation factor P (EF-P) OB domain; Pssm-ID: 460077 [Multi-domain] Cd Length: 54 Bit Score: 86.69 E-value: 4.72e-23
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EFP_N | pfam08207 | Elongation factor P (EF-P) KOW-like domain; |
3-60 | 5.68e-23 | ||||
Elongation factor P (EF-P) KOW-like domain; Pssm-ID: 429864 [Multi-domain] Cd Length: 58 Bit Score: 86.33 E-value: 5.68e-23
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Blast search parameters | ||||
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