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Conserved domains on  [gi|489535454|ref|WP_003440181|]
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GntR family transcriptional regulator [Clostridioides difficile]

Protein Classification

GntR family transcriptional regulator( domain architecture ID 11448193)

GntR family transcriptional regulator simlar to MngR, which is involved in the regulation of mannosyl-glycerate transport and metabolism

CATH:  1.10.10.10
Gene Ontology:  GO:0003677|GO:0003700
PubMed:  33509775|26172911|2060763

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YhcF COG1725
DNA-binding transcriptional regulator YhcF, GntR family [Transcription];
5-116 1.04e-38

DNA-binding transcriptional regulator YhcF, GntR family [Transcription];


:

Pssm-ID: 441331 [Multi-domain]  Cd Length: 114  Bit Score: 126.06  E-value: 1.04e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489535454   5 ISNTSDKPLYQQIKEQIKEAIFTEELKEGDAMPSIRNFANDLKVSILTIRRVYEELENEGFLTRQVGIGTFISTGNLEIL 84
Cdd:COG1725    3 IDFDSGVPIYEQIADQIKEAIASGELKPGDRLPSVRELAAELGVNPNTVAKAYRELEDEGLIETRRGKGTFVAEDARELL 82

                         90       100       110
                 ....*....|....*....|....*....|..
gi 489535454  85 RDSKRRIVEQKMADMIKDAKALGITQIELQEM 116
Cdd:COG1725   83 EERREEFLEEALRELVAEARRLGLSLEELLEL 114
 
Name Accession Description Interval E-value
YhcF COG1725
DNA-binding transcriptional regulator YhcF, GntR family [Transcription];
5-116 1.04e-38

DNA-binding transcriptional regulator YhcF, GntR family [Transcription];


Pssm-ID: 441331 [Multi-domain]  Cd Length: 114  Bit Score: 126.06  E-value: 1.04e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489535454   5 ISNTSDKPLYQQIKEQIKEAIFTEELKEGDAMPSIRNFANDLKVSILTIRRVYEELENEGFLTRQVGIGTFISTGNLEIL 84
Cdd:COG1725    3 IDFDSGVPIYEQIADQIKEAIASGELKPGDRLPSVRELAAELGVNPNTVAKAYRELEDEGLIETRRGKGTFVAEDARELL 82

                         90       100       110
                 ....*....|....*....|....*....|..
gi 489535454  85 RDSKRRIVEQKMADMIKDAKALGITQIELQEM 116
Cdd:COG1725   83 EERREEFLEEALRELVAEARRLGLSLEELLEL 114
WHTH_GntR cd07377
Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional ...
 12-77 1.77e-22

Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; This CD represents the winged HTH DNA-binding domain of the GntR (named after the gluconate operon repressor in Bacillus subtilis) family of bacterial transcriptional regulators and their putative homologs found in eukaryota and archaea. The GntR family has over 6000 members distributed among almost all bacterial species, which is comprised of FadR, HutC, MocR, YtrA, AraR, PlmA, and other subfamilies for the regulation of the most varied biological process. The monomeric proteins of the GntR family are characterized by two function domains: a small highly conserved winged helix-turn-helix prokaryotic DNA binding domain in the N-terminus, and a very diverse regulatory ligand-binding domain in the C-terminus for effector-binding/oligomerization, which provides the basis for the subfamily classifications. Binding of the effector to GntR-like transcriptional regulators is presumed to result in a conformational change that regulates the DNA-binding affinity of the repressor. The GntR-like proteins bind as dimers, where each monomer recognizes a half-site of 2-fold symmetric DNA sequences.


Pssm-ID: 153418 [Multi-domain]  Cd Length: 66  Bit Score: 83.27  E-value: 1.77e-22
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489535454  12 PLYQQIKEQIKEAIFTEELKEGDAMPSIRNFANDLKVSILTIRRVYEELENEGFLTRQVGIGTFIS 77
Cdd:cd07377    1 PLYEQIADQLREAILSGELKPGDRLPSERELAEELGVSRTTVREALRELEAEGLVERRPGRGTFVA 66
GntR pfam00392
Bacterial regulatory proteins, gntR family; This family of regulatory proteins consists of the ...
 13-76 1.08e-11

Bacterial regulatory proteins, gntR family; This family of regulatory proteins consists of the N-terminal HTH region of GntR-like bacterial transcription factors. At the C-terminus there is usually an effector-binding/oligomerization domain. The GntR-like proteins include the following sub-families: MocR, YtrR, FadR, AraR, HutC and PlmA, DevA, DasR. Many of these proteins have been shown experimentally to be autoregulatory, enabling the prediction of operator sites and the discovery of cis/trans relationships. The DasR regulator has been shown to be a global regulator of primary metabolism and development in Streptomyces coelicolor.


Pssm-ID: 306822 [Multi-domain]  Cd Length: 64  Bit Score: 55.70  E-value: 1.08e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489535454   13 LYQQIKEQIKEAIFTEELKEGDAMPSIRNFANDLKVSILTIRRVYEELENEGFLTRQVGIGTFI 76
Cdd:pfam00392   1 LYEQVYARLREDILSGRLRPGDKLPSERELAAEFGVSRTTVREALRRLEAEGLVERRQGRGTFV 64
HTH_GNTR smart00345
helix_turn_helix gluconate operon transcriptional repressor;
17-76 4.48e-11

helix_turn_helix gluconate operon transcriptional repressor;


Pssm-ID: 197669 [Multi-domain]  Cd Length: 60  Bit Score: 54.12  E-value: 4.48e-11
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 489535454    17 IKEQIKEAIFTEELKEGDAMPSIRNFANDLKVSILTIRRVYEELENEGFLTRQVGIGTFI 76
Cdd:smart00345   1 VAERLREDIVSGELRPGDKLPSERELAAQLGVSRTTVREALSRLEAEGLVQRRPGSGTFV 60
PRK14999 PRK14999
histidine utilization repressor; Provisional
 1-77 1.09e-08

histidine utilization repressor; Provisional


Pssm-ID: 184961 [Multi-domain]  Cd Length: 241  Bit Score: 51.09  E-value: 1.09e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489535454   1 MKVLISNTSDKPLYQQIKEQIKEAIFTEELKEGDAMPSIRNFANDLKVSILTIRRVYEELENEGFLTRQVGIGTFIS 77
Cdd:PRK14999   1 MYSSRSRSAPAPFYETVKQDICKKIAGGVWQPHDRIPSEAELVAQYGFSRMTINRALRELTDEGWLVRLQGVGTFVA 77
C_P_lyase_phnF TIGR02325
phosphonates metabolism transcriptional regulator PhnF; All members of the seed alignment for ...
 5-106 2.04e-06

phosphonates metabolism transcriptional regulator PhnF; All members of the seed alignment for this family are predicted helix-turn-helix transcriptional regulatory proteins of the broader gntR and are found associated with genes for the import and degradation of phosphonates and/or related compounds (e.g. phosphonites) with a direct C-P bond. [Transport and binding proteins, Anions, Regulatory functions, DNA interactions]


Pssm-ID: 131378 [Multi-domain]  Cd Length: 238  Bit Score: 44.77  E-value: 2.04e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489535454    5 ISNTSDKPLYQQIKEQIKEAIFTEELKEGDAMPSIRNFANDLKVSILTIRRVYEELENEGFLTRQVGIGTFISTGNLEIL 84
Cdd:TIGR02325   1 IERTSGVALWRQIADKIEQEIAAGHLRAGDYLPAEMQLAERFGVNRHTVRRAIAALVERGLLRAEQGRGTFVAARRIDYP 80

                          90       100
                  ....*....|....*....|..
gi 489535454   85 RDSKRRIvEQKMADMIKDAKAL 106
Cdd:TIGR02325  81 LSARTRF-SQNLADQGREPTGE 101
 
Name Accession Description Interval E-value
YhcF COG1725
DNA-binding transcriptional regulator YhcF, GntR family [Transcription];
5-116 1.04e-38

DNA-binding transcriptional regulator YhcF, GntR family [Transcription];


Pssm-ID: 441331 [Multi-domain]  Cd Length: 114  Bit Score: 126.06  E-value: 1.04e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489535454   5 ISNTSDKPLYQQIKEQIKEAIFTEELKEGDAMPSIRNFANDLKVSILTIRRVYEELENEGFLTRQVGIGTFISTGNLEIL 84
Cdd:COG1725    3 IDFDSGVPIYEQIADQIKEAIASGELKPGDRLPSVRELAAELGVNPNTVAKAYRELEDEGLIETRRGKGTFVAEDARELL 82

                         90       100       110
                 ....*....|....*....|....*....|..
gi 489535454  85 RDSKRRIVEQKMADMIKDAKALGITQIELQEM 116
Cdd:COG1725   83 EERREEFLEEALRELVAEARRLGLSLEELLEL 114
ARO8 COG1167
DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain ...
 1-77 2.72e-23

DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain [Transcription, Amino acid transport and metabolism]; DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain is part of the Pathway/BioSystem: Lysine biosynthesis


Pssm-ID: 440781 [Multi-domain]  Cd Length: 471  Bit Score: 92.97  E-value: 2.72e-23
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489535454   1 MKVLISNTSDKPLYQQIKEQIKEAIFTEELKEGDAMPSIRNFANDLKVSILTIRRVYEELENEGFLTRQVGIGTFIS 77
Cdd:COG1167    1 MLIRLDRDSSGPLYLQLADALREAILSGRLPPGDRLPSSRELAAQLGVSRSTVVRAYEELEAEGLIESRPGSGTFVA 77
WHTH_GntR cd07377
Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional ...
 12-77 1.77e-22

Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; This CD represents the winged HTH DNA-binding domain of the GntR (named after the gluconate operon repressor in Bacillus subtilis) family of bacterial transcriptional regulators and their putative homologs found in eukaryota and archaea. The GntR family has over 6000 members distributed among almost all bacterial species, which is comprised of FadR, HutC, MocR, YtrA, AraR, PlmA, and other subfamilies for the regulation of the most varied biological process. The monomeric proteins of the GntR family are characterized by two function domains: a small highly conserved winged helix-turn-helix prokaryotic DNA binding domain in the N-terminus, and a very diverse regulatory ligand-binding domain in the C-terminus for effector-binding/oligomerization, which provides the basis for the subfamily classifications. Binding of the effector to GntR-like transcriptional regulators is presumed to result in a conformational change that regulates the DNA-binding affinity of the repressor. The GntR-like proteins bind as dimers, where each monomer recognizes a half-site of 2-fold symmetric DNA sequences.


Pssm-ID: 153418 [Multi-domain]  Cd Length: 66  Bit Score: 83.27  E-value: 1.77e-22
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489535454  12 PLYQQIKEQIKEAIFTEELKEGDAMPSIRNFANDLKVSILTIRRVYEELENEGFLTRQVGIGTFIS 77
Cdd:cd07377    1 PLYEQIADQLREAILSGELKPGDRLPSERELAEELGVSRTTVREALRELEAEGLVERRPGRGTFVA 66
MngR COG2188
DNA-binding transcriptional regulator, GntR family [Transcription];
8-82 1.12e-18

DNA-binding transcriptional regulator, GntR family [Transcription];


Pssm-ID: 441791 [Multi-domain]  Cd Length: 238  Bit Score: 77.98  E-value: 1.12e-18
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489535454   8 TSDKPLYQQIKEQIKEAIFTEELKEGDAMPSIRNFANDLKVSILTIRRVYEELENEGFLTRQVGIGTFISTGNLE 82
Cdd:COG2188    1 SSPVPLYLQIADALRERIESGELPPGDRLPSERELAEEFGVSRMTVRKALDELVEEGLLERRQGRGTFVAEPKIE 75
GntR pfam00392
Bacterial regulatory proteins, gntR family; This family of regulatory proteins consists of the ...
 13-76 1.08e-11

Bacterial regulatory proteins, gntR family; This family of regulatory proteins consists of the N-terminal HTH region of GntR-like bacterial transcription factors. At the C-terminus there is usually an effector-binding/oligomerization domain. The GntR-like proteins include the following sub-families: MocR, YtrR, FadR, AraR, HutC and PlmA, DevA, DasR. Many of these proteins have been shown experimentally to be autoregulatory, enabling the prediction of operator sites and the discovery of cis/trans relationships. The DasR regulator has been shown to be a global regulator of primary metabolism and development in Streptomyces coelicolor.


Pssm-ID: 306822 [Multi-domain]  Cd Length: 64  Bit Score: 55.70  E-value: 1.08e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489535454   13 LYQQIKEQIKEAIFTEELKEGDAMPSIRNFANDLKVSILTIRRVYEELENEGFLTRQVGIGTFI 76
Cdd:pfam00392   1 LYEQVYARLREDILSGRLRPGDKLPSERELAAEFGVSRTTVREALRRLEAEGLVERRQGRGTFV 64
FadR COG2186
DNA-binding transcriptional regulator, FadR family [Transcription];
11-124 2.72e-11

DNA-binding transcriptional regulator, FadR family [Transcription];


Pssm-ID: 441789 [Multi-domain]  Cd Length: 232  Bit Score: 58.41  E-value: 2.72e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489535454  11 KPLYQQIKEQIKEAIFTEELKEGDAMPSIRNFANDLKVSILTIRRVYEELENEGFLTRQVGIGTFIS----TGNLEILRD 86
Cdd:COG2186    6 RSLAEQVAEQLRELILSGELKPGDRLPSERELAEQLGVSRTTVREALRALEALGLVEVRQGGGTFVRepspWALLDPLAL 85

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 489535454  87 SK-------------RRIVEQKMADMIkdakALGITQIELQEMMDILYQED 124
Cdd:COG2186   86 LLalddaslrdlleaRLALEPEAARLA----AERATDEDLARLEAALAEME 132
HTH_GNTR smart00345
helix_turn_helix gluconate operon transcriptional repressor;
17-76 4.48e-11

helix_turn_helix gluconate operon transcriptional repressor;


Pssm-ID: 197669 [Multi-domain]  Cd Length: 60  Bit Score: 54.12  E-value: 4.48e-11
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 489535454    17 IKEQIKEAIFTEELKEGDAMPSIRNFANDLKVSILTIRRVYEELENEGFLTRQVGIGTFI 76
Cdd:smart00345   1 VAERLREDIVSGELRPGDKLPSERELAAQLGVSRTTVREALSRLEAEGLVQRRPGSGTFV 60
PRK14999 PRK14999
histidine utilization repressor; Provisional
 1-77 1.09e-08

histidine utilization repressor; Provisional


Pssm-ID: 184961 [Multi-domain]  Cd Length: 241  Bit Score: 51.09  E-value: 1.09e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489535454   1 MKVLISNTSDKPLYQQIKEQIKEAIFTEELKEGDAMPSIRNFANDLKVSILTIRRVYEELENEGFLTRQVGIGTFIS 77
Cdd:PRK14999   1 MYSSRSRSAPAPFYETVKQDICKKIAGGVWQPHDRIPSEAELVAQYGFSRMTINRALRELTDEGWLVRLQGVGTFVA 77
PRK11402 PRK11402
transcriptional regulator PhoB;
4-82 3.16e-07

transcriptional regulator PhoB;


Pssm-ID: 183118 [Multi-domain]  Cd Length: 241  Bit Score: 47.14  E-value: 3.16e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489535454   4 LISNTSDKPLYQQIKEQIKEAIFTEELKEGDAMPSIRNFANDLKVSILTIRRVYEELENEGFLTRQVGIGTFISTGNLE 82
Cdd:PRK11402   1 ATDRYSHQLLYATVRQRLLDDIAQGVYQAGQQIPTENELCTQYNVSRITIRKAISDLVADGVLIRWQGKGTFVQSQKVE 79
C_P_lyase_phnF TIGR02325
phosphonates metabolism transcriptional regulator PhnF; All members of the seed alignment for ...
 5-106 2.04e-06

phosphonates metabolism transcriptional regulator PhnF; All members of the seed alignment for this family are predicted helix-turn-helix transcriptional regulatory proteins of the broader gntR and are found associated with genes for the import and degradation of phosphonates and/or related compounds (e.g. phosphonites) with a direct C-P bond. [Transport and binding proteins, Anions, Regulatory functions, DNA interactions]


Pssm-ID: 131378 [Multi-domain]  Cd Length: 238  Bit Score: 44.77  E-value: 2.04e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489535454    5 ISNTSDKPLYQQIKEQIKEAIFTEELKEGDAMPSIRNFANDLKVSILTIRRVYEELENEGFLTRQVGIGTFISTGNLEIL 84
Cdd:TIGR02325   1 IERTSGVALWRQIADKIEQEIAAGHLRAGDYLPAEMQLAERFGVNRHTVRRAIAALVERGLLRAEQGRGTFVAARRIDYP 80

                          90       100
                  ....*....|....*....|..
gi 489535454   85 RDSKRRIvEQKMADMIKDAKAL 106
Cdd:TIGR02325  81 LSARTRF-SQNLADQGREPTGE 101
PRK09764 PRK09764
GntR family transcriptional regulator;
11-76 3.14e-06

GntR family transcriptional regulator;


Pssm-ID: 182065 [Multi-domain]  Cd Length: 240  Bit Score: 44.43  E-value: 3.14e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489535454  11 KPLYQQIKEQIKEAIFTEELKEGDAMPSIRNFANDLKVSILTIRRVYEELENEGFLTRQVGIGTFI 76
Cdd:PRK09764   4 KPLYRQIADRIREQIARGELKPGDALPTESALQTEFGVSRVTVRQALRQLVEQQILESIQGSGTYV 69
PRK10079 PRK10079
phosphonate metabolism transcriptional regulator PhnF; Provisional
 8-76 6.24e-06

phosphonate metabolism transcriptional regulator PhnF; Provisional


Pssm-ID: 182227 [Multi-domain]  Cd Length: 241  Bit Score: 43.61  E-value: 6.24e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489535454   8 TSDKPLYQQIKEQIKEAIfTEELKEGDAMPSIRNFANDLKVSILTIRRVYEELENEGFLTRQVGIGTFI 76
Cdd:PRK10079   8 TSYPTRYQEIAAKLEQEL-RQHYRCGDYLPAEQQLAARYEVNRHTLRRAIDQLVEKGWVQRRQGVGVLV 75
PRK15481 PRK15481
transcriptional regulatory protein PtsJ; Provisional
 16-77 1.98e-04

transcriptional regulatory protein PtsJ; Provisional


Pssm-ID: 185378 [Multi-domain]  Cd Length: 431  Bit Score: 39.26  E-value: 1.98e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489535454  16 QIKEQIKEAIFTEELKEGDAMPSIRNFANDLKVSILTIRRVYEELENEGFLTRQVGIGTFIS 77
Cdd:PRK15481   9 EIFDSIRQLIQAGRLRPGDSLPPVRELASELGVNRNTVAAAYKRLVTAGLAQSQGRNGTVIR 70
GntR COG1802
DNA-binding transcriptional regulator, GntR family [Transcription];
11-86 4.68e-04

DNA-binding transcriptional regulator, GntR family [Transcription];


Pssm-ID: 441407 [Multi-domain]  Cd Length: 222  Bit Score: 37.98  E-value: 4.68e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489535454  11 KPLYQQIKEQIKEAIFTEELKEGDAMpSIRNFANDLKVSILTIRRVYEELENEGFLTRQVGIGTFISTGNLEILRD 86
Cdd:COG1802   10 ESLAEQVYEALREAILSGELPPGERL-SEAELAERLGVSRTPVREALRRLEAEGLVEIRPNRGARVAPLSPEEIRE 84
PRK03837 PRK03837
transcriptional regulator NanR; Provisional
 11-94 3.04e-03

transcriptional regulator NanR; Provisional


Pssm-ID: 235166 [Multi-domain]  Cd Length: 241  Bit Score: 35.77  E-value: 3.04e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489535454  11 KPLYQQIKEQIKEAIFTEELKEGDAMPSIRNFANDLKVSILTIRRVYEELENEGFLTrqvgigtfISTGN-LEILRDSKR 89
Cdd:PRK03837  12 KKLSEEVEERLEQMIRSGEFGPGDQLPSERELMAFFGVGRPAVREALQALKRKGLVQ--------ISHGErARVSRPSAD 83


                 ....*
gi 489535454  90 RIVEQ 94
Cdd:PRK03837  84 TIIGQ 88
pdhR PRK09464
pyruvate dehydrogenase complex transcriptional repressor PdhR;
17-78 7.09e-03

pyruvate dehydrogenase complex transcriptional repressor PdhR;


Pssm-ID: 181879 [Multi-domain]  Cd Length: 254  Bit Score: 34.61  E-value: 7.09e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489535454  17 IKEQIKEAIFTEELKEGDAMPSIRNFANDLKVSILTIRRVYEELENEGFLTRQVGIGTFIST 78
Cdd:PRK09464  15 IEQQLEFLILEGTLRPGEKLPPERELAKQFDVSRPSLREAIQRLEAKGLLLRRQGGGTFVQS 76
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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