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Conserved domains on  [gi|489327667|ref|WP_003234958|]
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MULTISPECIES: RNA polymerase sigma factor SigW [Bacillus]

Protein Classification

RNA polymerase sigma factor SigW( domain architecture ID 11484437)

RNA polymerase sigma factor SigW controls genes involved in response to cell envelope stress such as antimicrobial peptides, alkaline pH, transport processes and detoxification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK09641 PRK09641
RNA polymerase sigma factor SigW; Provisional
1-187 4.01e-130

RNA polymerase sigma factor SigW; Provisional


:

Pssm-ID: 182012 [Multi-domain]  Cd Length: 187  Bit Score: 362.48  E-value: 4.01e-130
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667   1 MEMMIKKRIKQVKKGDQDAFADIVDIYKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATNL 80
Cdd:PRK09641   1 MDLLIKRLIKQVKKGDQNAFAELVDLYKDKIYQLCYRMLGNRHEAEDAAQEAFIRAYVNIDSYDINRKFSTWLYRIATNL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  81 TIDRIRKKKPDYYLDAEVAGTEGLTMYSQIVADGVLPEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGE 160
Cdd:PRK09641  81 TIDRLRKRKPDYYLDAEVAGTEGLTMYSQLAADDALPEEQVVSLELQETIQEAILQLPEKYRTVIVLKYIEDLSLKEISE 160
                        170       180
                 ....*....|....*....|....*..
gi 489327667 161 ILNIPVGTVKTRIHRGREALRKQLRDL 187
Cdd:PRK09641 161 ILDLPVGTVKTRIHRGREALRKQLRHL 187
 
Name Accession Description Interval E-value
PRK09641 PRK09641
RNA polymerase sigma factor SigW; Provisional
1-187 4.01e-130

RNA polymerase sigma factor SigW; Provisional


Pssm-ID: 182012 [Multi-domain]  Cd Length: 187  Bit Score: 362.48  E-value: 4.01e-130
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667   1 MEMMIKKRIKQVKKGDQDAFADIVDIYKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATNL 80
Cdd:PRK09641   1 MDLLIKRLIKQVKKGDQNAFAELVDLYKDKIYQLCYRMLGNRHEAEDAAQEAFIRAYVNIDSYDINRKFSTWLYRIATNL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  81 TIDRIRKKKPDYYLDAEVAGTEGLTMYSQIVADGVLPEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGE 160
Cdd:PRK09641  81 TIDRLRKRKPDYYLDAEVAGTEGLTMYSQLAADDALPEEQVVSLELQETIQEAILQLPEKYRTVIVLKYIEDLSLKEISE 160
                        170       180
                 ....*....|....*....|....*..
gi 489327667 161 ILNIPVGTVKTRIHRGREALRKQLRDL 187
Cdd:PRK09641 161 ILDLPVGTVKTRIHRGREALRKQLRHL 187
SigW_bacill TIGR02948
RNA polymerase sigma-W factor; This sigma factor is restricted to certain lineages of the ...
1-187 6.69e-119

RNA polymerase sigma-W factor; This sigma factor is restricted to certain lineages of the order Bacillales.


Pssm-ID: 131993 [Multi-domain]  Cd Length: 187  Bit Score: 334.17  E-value: 6.69e-119
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667    1 MEMMIKKRIKQVKKGDQDAFADIVDIYKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATNL 80
Cdd:TIGR02948   1 MDSIIKKRIKEVRKGDENAFADLVDLYKDKIYQLCYRMLGNVHEAEDVAQEAFIRAYTNIDTYDIQRKFSTWLYRIATNL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667   81 TIDRIRKKKPDYYLDAEVAGTEGLTMYSQIVADGVLPEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGE 160
Cdd:TIGR02948  81 TIDRLRKRKPDFYLDDEVQGTDGLTMESQLAADEAPPEDQVISLELRDTIQQEIQALPPKYRMVIVLKYMEDLSLKEISE 160
                         170       180
                  ....*....|....*....|....*..
gi 489327667  161 ILNIPVGTVKTRIHRGREALRKQLRDL 187
Cdd:TIGR02948 161 ILDLPVGTVKTRIHRGREALRKQLRHL 187
RpoE COG1595
DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; ...
9-186 1.38e-60

DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; DNA-directed RNA polymerase specialized sigma subunit, sigma24 family is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 441203 [Multi-domain]  Cd Length: 181  Bit Score: 186.35  E-value: 1.38e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667   9 IKQVKKGDQDAFADIVDIYKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATNLTIDRIRKK 88
Cdd:COG1595    8 LERLRAGDEAAFEELYERYRPRLYRYARRLLGDRADAEDLVQETFLRLWRKLDSFRGRGSFRAWLYRIARNLAIDHLRKR 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  89 KPDYYLDAEVAgtegltmySQIVADGVLPEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGT 168
Cdd:COG1595   88 RRRRELLDELA--------EELPDEAADPEEALEAEELLEALLAALERLPPRQREVLVLRYLEGLSYAEIAEILGISEGT 159
                        170
                 ....*....|....*...
gi 489327667 169 VKTRIHRGREALRKQLRD 186
Cdd:COG1595  160 VKSRLSRARKKLREALEE 177
Sigma70_r2 pfam04542
Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. ...
23-89 4.29e-20

Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. All members of this class of sigma-factor contain region 2. The high conservation is due to region 2 containing both the -10 promoter recognition helix and the primary core RNA polymerase binding determinant. The core binding helix, interacts with the clamp domain of the largest polymerase subunit, beta prime. The aromatic residues of the recognition helix, found at the C-terminus of this domain are though to mediate strand separation, thereby allowing transcription initiation.


Pssm-ID: 427998 [Multi-domain]  Cd Length: 71  Bit Score: 79.55  E-value: 4.29e-20
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489327667   23 IVDIYKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNIDSFDINR--KFSTWLYRIATNLTIDRIRKKK 89
Cdd:pfam04542   1 LVERYLPLVYSLARRYLGDGADAEDLVQEGFLGLWRAIERFDPERgvSFSTWLYTIIRNAIIDYLRKQR 69
Sigma70_r4 cd06171
Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in ...
130-181 1.37e-15

Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or plastid core RNA polymerase to specific promoter elements located upstream of transcription initiation points. The SR4 of Ec sigma70 and other essential primary SFs contact promoter sequences located 35 base-pairs upstream of the initiation point, recognizing a 6-base-pair -35 consensus TTGACA. Sigma70 related SFs also include SFs which are dispensable for bacterial cell growth for example Ec sigmaS, SFs which activate regulons in response to a specific signal for example heat-shock Ec sigmaH, and a group of SFs which includes the extracytoplasmic function (ECF) SFs and is typified by Ec sigmaE which contains SR2 and -4 only. ECF SFs direct the transcription of genes that regulate various responses including periplasmic stress and pathogenesis. Ec sigmaE SR4 also contacts the -35 element, but recognizes a different consensus (a 7-base-pair GGAACTT). Plant SFs recognize sigma70 type promoters and direct transcription of the major plastid RNA polymerase, plastid-encoded RNA polymerase (PEP).


Pssm-ID: 100119 [Multi-domain]  Cd Length: 55  Bit Score: 67.51  E-value: 1.37e-15
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 489327667 130 IQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKTRIHRGREALR 181
Cdd:cd06171    4 LEEALDKLPEREREVILLRFGEGLSYEEIAEILGISRSTVRQRLHRALKKLR 55
 
Name Accession Description Interval E-value
PRK09641 PRK09641
RNA polymerase sigma factor SigW; Provisional
1-187 4.01e-130

RNA polymerase sigma factor SigW; Provisional


Pssm-ID: 182012 [Multi-domain]  Cd Length: 187  Bit Score: 362.48  E-value: 4.01e-130
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667   1 MEMMIKKRIKQVKKGDQDAFADIVDIYKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATNL 80
Cdd:PRK09641   1 MDLLIKRLIKQVKKGDQNAFAELVDLYKDKIYQLCYRMLGNRHEAEDAAQEAFIRAYVNIDSYDINRKFSTWLYRIATNL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  81 TIDRIRKKKPDYYLDAEVAGTEGLTMYSQIVADGVLPEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGE 160
Cdd:PRK09641  81 TIDRLRKRKPDYYLDAEVAGTEGLTMYSQLAADDALPEEQVVSLELQETIQEAILQLPEKYRTVIVLKYIEDLSLKEISE 160
                        170       180
                 ....*....|....*....|....*..
gi 489327667 161 ILNIPVGTVKTRIHRGREALRKQLRDL 187
Cdd:PRK09641 161 ILDLPVGTVKTRIHRGREALRKQLRHL 187
SigW_bacill TIGR02948
RNA polymerase sigma-W factor; This sigma factor is restricted to certain lineages of the ...
1-187 6.69e-119

RNA polymerase sigma-W factor; This sigma factor is restricted to certain lineages of the order Bacillales.


Pssm-ID: 131993 [Multi-domain]  Cd Length: 187  Bit Score: 334.17  E-value: 6.69e-119
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667    1 MEMMIKKRIKQVKKGDQDAFADIVDIYKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATNL 80
Cdd:TIGR02948   1 MDSIIKKRIKEVRKGDENAFADLVDLYKDKIYQLCYRMLGNVHEAEDVAQEAFIRAYTNIDTYDIQRKFSTWLYRIATNL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667   81 TIDRIRKKKPDYYLDAEVAGTEGLTMYSQIVADGVLPEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGE 160
Cdd:TIGR02948  81 TIDRLRKRKPDFYLDDEVQGTDGLTMESQLAADEAPPEDQVISLELRDTIQQEIQALPPKYRMVIVLKYMEDLSLKEISE 160
                         170       180
                  ....*....|....*....|....*..
gi 489327667  161 ILNIPVGTVKTRIHRGREALRKQLRDL 187
Cdd:TIGR02948 161 ILDLPVGTVKTRIHRGREALRKQLRHL 187
RpoE COG1595
DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; ...
9-186 1.38e-60

DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; DNA-directed RNA polymerase specialized sigma subunit, sigma24 family is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 441203 [Multi-domain]  Cd Length: 181  Bit Score: 186.35  E-value: 1.38e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667   9 IKQVKKGDQDAFADIVDIYKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATNLTIDRIRKK 88
Cdd:COG1595    8 LERLRAGDEAAFEELYERYRPRLYRYARRLLGDRADAEDLVQETFLRLWRKLDSFRGRGSFRAWLYRIARNLAIDHLRKR 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  89 KPDYYLDAEVAgtegltmySQIVADGVLPEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGT 168
Cdd:COG1595   88 RRRRELLDELA--------EELPDEAADPEEALEAEELLEALLAALERLPPRQREVLVLRYLEGLSYAEIAEILGISEGT 159
                        170
                 ....*....|....*...
gi 489327667 169 VKTRIHRGREALRKQLRD 186
Cdd:COG1595  160 VKSRLSRARKKLREALEE 177
PRK09652 PRK09652
RNA polymerase sigma factor RpoE; Provisional
12-187 9.14e-54

RNA polymerase sigma factor RpoE; Provisional


Pssm-ID: 236608 [Multi-domain]  Cd Length: 182  Bit Score: 169.22  E-value: 9.14e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  12 VKKGDQDAFADIVDIYKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATNLTIDRIRKKK-- 89
Cdd:PRK09652   4 VQRGDRAAFALLVRRYQPRVKRLLSRLTRDPADAEDLVQETFIKAYRALHSFRGGAAFYTWLYRIARNTAINYLRKQGrr 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  90 -PDYYLDAEVAGTEGLtmySQIVADGVLPEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGT 168
Cdd:PRK09652  84 pPASDVDAEEAEDFDL---ADALRDISTPENELLSAELEQRVRAAIESLPEELRTAITLREIEGLSYEEIAEIMGCPIGT 160
                        170
                 ....*....|....*....
gi 489327667 169 VKTRIHRGREALRKQLRDL 187
Cdd:PRK09652 161 VRSRIFRAREALRAKLQPL 179
sigma70-ECF TIGR02937
RNA polymerase sigma factor, sigma-70 family; This model encompasses all varieties of the ...
18-184 4.81e-43

RNA polymerase sigma factor, sigma-70 family; This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.


Pssm-ID: 274357 [Multi-domain]  Cd Length: 158  Bit Score: 140.95  E-value: 4.81e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667   18 DAFADIVDIYKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATNLTIDRIRKKKPDYYLDAE 97
Cdd:TIGR02937   1 EAFEELYERYLPLVYRYARRYLGDDADAEDLVQEAFLKLLEALDRFDPEGSFKAWLFRIARNLILDYLRRKRRLRRELDL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667   98 VAgtegltmysQIVADGVLPEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKTRIHRGR 177
Cdd:TIGR02937  81 LE---------ELLDSDPSPEEELEQEEEREALREALEKLPEREREVLVLRYLEGLSYKEIAEILGISVGTVKRRLKRAR 151

                  ....*..
gi 489327667  178 EALRKQL 184
Cdd:TIGR02937 152 KKLRELL 158
PRK11924 PRK11924
RNA polymerase sigma factor; Provisional
14-186 7.27e-42

RNA polymerase sigma factor; Provisional


Pssm-ID: 183384 [Multi-domain]  Cd Length: 179  Bit Score: 138.57  E-value: 7.27e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  14 KGDQDAFADIVDIYKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATNLTIDRIRKKKPdyy 93
Cdd:PRK11924   9 TGDKEAFSELFRPHAPDLLRYARRQLGDRALAEDAVQEAFLRAWRKADLFNGKGSARTWLLTIARNVCYDLLRRRRR--- 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  94 ldaEVAGTEGLTMYSQIVADGVLPEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKTRI 173
Cdd:PRK11924  86 ---EKAVLSDDALEPEFAETAETPEAALLAKDDLARIDRCLDALPVKQREVFLLRYVEGLSYREIAEILGVPVGTVKSRL 162
                        170
                 ....*....|...
gi 489327667 174 HRGREALRKQLRD 186
Cdd:PRK11924 163 RRARQLLRECLEA 175
PRK09638 PRK09638
RNA polymerase sigma factor SigY; Reviewed
1-186 2.71e-38

RNA polymerase sigma factor SigY; Reviewed


Pssm-ID: 182010 [Multi-domain]  Cd Length: 176  Bit Score: 129.37  E-value: 2.71e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667   1 MEMMIKKRIKQVKKGDQDAFADIVDIYKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATNL 80
Cdd:PRK09638   1 MQMDEKELIQKAKKGDDAALTTLFQQHYSFLYKYLLKLTLDPDLAEDLVQETMLKAIENLSSFQGRSKFSTWLISIASRL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  81 TIDRIRKKKPDYYLDAevagtegltMYSQIVADGVLPEDAVVSLELSnTIQQKILKLPDKYRTVIVLKYIDELSLIEIGE 160
Cdd:PRK09638  81 YKDHLRKQKREKLRLQ---------RAKEETLRKEKWEAAIKGAEWS-EMLDALSKLDPEFRAPVILKHYYGYTYEEIAK 150
                        170       180
                 ....*....|....*....|....*.
gi 489327667 161 ILNIPVGTVKTRIHRGREALRKQLRD 186
Cdd:PRK09638 151 MLNIPEGTVKSRVHHGIKQLRKEWGQ 176
PRK11922 PRK11922
RNA polymerase sigma factor; Provisional
9-184 1.68e-37

RNA polymerase sigma factor; Provisional


Pssm-ID: 237024 [Multi-domain]  Cd Length: 231  Bit Score: 129.31  E-value: 1.68e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667   9 IKQVKKGDQDAFADIVDIYKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATNLTIDRIRKK 88
Cdd:PRK11922  21 VARVLAGDEAAFEALMRRHNRRLYRTARAILRNDAEAEDVVQEAYLRAFRALGTFRGDASLSTWLSRIVLNEALGRLRRR 100
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  89 KPDYYLD-AEVAGTEGLTMYSQIVADGVLPEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVG 167
Cdd:PRK11922 101 RRLVNLAeMVMASTIAGGERTPLADPAEDPERAAARREIRALLERAIDALPDAFRAVFVLRVVEELSVEETAQALGLPEE 180
                        170
                 ....*....|....*..
gi 489327667 168 TVKTRIHRGREALRKQL 184
Cdd:PRK11922 181 TVKTRLHRARRLLRESL 197
PRK05602 PRK05602
RNA polymerase sigma factor; Reviewed
9-187 2.03e-34

RNA polymerase sigma factor; Reviewed


Pssm-ID: 235530 [Multi-domain]  Cd Length: 186  Bit Score: 119.76  E-value: 2.03e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667   9 IKQVKKGDQDAFADIVDIYKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNIDSFDI-NRKFSTWLYRIATNLTIDRIRK 87
Cdd:PRK05602  11 LARVAAGDPAAFRVLVARKLPRLLALATRMLGDPAEAEDVAQETFLRIWKQAPSWRPgEARFDTWLHRVVLNLCYDRLRR 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  88 KKpdyyldaEVAgTEGLtmySQIVADGVLPEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVG 167
Cdd:PRK05602  91 RR-------EVP-VEDA---PDVPDPAPGPDAGLEARQRARRVEQALAALPERQREAIVLQYYQGLSNIEAAAVMDISVD 159
                        170       180
                 ....*....|....*....|
gi 489327667 168 TVKTRIHRGREALRKQLRDL 187
Cdd:PRK05602 160 ALESLLARGRRALRAQLADL 179
algU PRK11923
RNA polymerase sigma factor AlgU; Provisional
9-187 2.75e-34

RNA polymerase sigma factor AlgU; Provisional


Pssm-ID: 171347 [Multi-domain]  Cd Length: 193  Bit Score: 119.91  E-value: 2.75e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667   9 IKQVKKGDQDAFADIVDIYKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATNLTIDRI--- 85
Cdd:PRK11923  11 VERVQRGDKRAFDLLVLKYQHKILGLIVRFVHDTAEAQDVAQEAFIKAYRALGNFRGDSAFYTWLYRIAINTAKNHLvsr 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  86 RKKKPDYYLDAEVA----GTEGLTmysqivaDGVLPEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEI 161
Cdd:PRK11923  91 GRRPPDSDVSSEDAefydGDHALK-------DIESPERALLRDEIEGTVHRTIQQLPEDLRTALTLREFDGLSYEDIASV 163
                        170       180
                 ....*....|....*....|....*.
gi 489327667 162 LNIPVGTVKTRIHRGREALRKQLRDL 187
Cdd:PRK11923 164 MQCPVGTVRSRIFRAREAIDKALQPL 189
PRK09647 PRK09647
RNA polymerase sigma factor SigE; Reviewed
22-184 6.58e-34

RNA polymerase sigma factor SigE; Reviewed


Pssm-ID: 236606 [Multi-domain]  Cd Length: 203  Bit Score: 119.12  E-value: 6.58e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  22 DIVDIYKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNIDSFDINrKFSTWLYRIATNLTIDRIRKKKPdyyLDAEVAGT 101
Cdd:PRK09647  32 ELVRQHADRVYRLAYRLSGNQHDAEDLTQETFIRVFRSLQNYQPG-TFEGWLHRITTNLFLDMVRRRAR---IRMEALPE 107
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667 102 EgltmYSQIVADGVLPEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKTRIHRGREALR 181
Cdd:PRK09647 108 D----YDRVPGDEPNPEQIYHDARLDPDLQAALDSLPPEFRAAVVLCDIEGLSYEEIAATLGVKLGTVRSRIHRGRQQLR 183

                 ...
gi 489327667 182 KQL 184
Cdd:PRK09647 184 AAL 186
SigE-fam_strep TIGR02983
RNA polymerase sigma-70 factor, sigma-E family; This group of similar sigma-70 factors ...
17-184 1.91e-29

RNA polymerase sigma-70 factor, sigma-E family; This group of similar sigma-70 factors includes the sigE factor from Streptomyces coelicolor. The family appears to include a paralagous expansion in the Streptomycetes lineage, while related Actinomycetales have at most two representatives.


Pssm-ID: 132028 [Multi-domain]  Cd Length: 162  Bit Score: 106.32  E-value: 1.91e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667   17 QDAFADIVDIYKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATNLTIDRIRKKKPDYYLDA 96
Cdd:TIGR02983   5 EEEFTAFVAARYPRLLRTAYLLTGDPHEAEDLVQEALVRTYVRWDRIRDPDAPDAYVRRVLVNLARSRWRRRRLLELPTR 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667   97 EVAGTEGltmysqivadgvlpEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKTRIHRG 176
Cdd:TIGR02983  85 ELPDAAA--------------PDPAPDVALRAALARALRRLPARQRAVVVLRYYEDLSEAQVAEALGISVGTVKSRLSRA 150

                  ....*...
gi 489327667  177 REALRKQL 184
Cdd:TIGR02983 151 LARLRELL 158
PRK09643 PRK09643
RNA polymerase sigma factor SigM; Reviewed
15-187 3.37e-28

RNA polymerase sigma factor SigM; Reviewed


Pssm-ID: 236604 [Multi-domain]  Cd Length: 192  Bit Score: 104.02  E-value: 3.37e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  15 GDQDAFADIVDIYKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATNLTIDRIRKKK--PDY 92
Cdd:PRK09643  24 GDRYAFGELFRRHHRRLWAVARRTSGTREDAADALQDAMLSAHRAAGSFRGDAAVSSWLHRIVVNACLDRLRRAKarPTV 103
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  93 YLD--AEVAGtegltmysqivadgvLPEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVK 170
Cdd:PRK09643 104 PLDdvYPVAQ---------------LERDPTARVETALAVQRALMRLPVEQRAALVAVDMQGYSVADAARMLGVAEGTVK 168
                        170
                 ....*....|....*..
gi 489327667 171 TRIHRGREALRKQLRDL 187
Cdd:PRK09643 169 SRCARGRARLAELLGYL 185
PRK09415 PRK09415
RNA polymerase factor sigma C; Reviewed
23-184 3.99e-28

RNA polymerase factor sigma C; Reviewed


Pssm-ID: 181835 [Multi-domain]  Cd Length: 179  Bit Score: 103.67  E-value: 3.99e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  23 IVDIYKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATNLTIDRIRKkkpdyYLDAEVAGTE 102
Cdd:PRK09415  21 IMNEYGQEVLQLVYSYVKNKEVAEDLTQEIFVKCYKSLHTYKGKSSLKTWLYRIAINHCKDYLKS-----WHNKKVIVTE 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667 103 GLTMYSQIVADgvLPEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKTRIHRGREALRK 182
Cdd:PRK09415  96 DIFTYMESQKE--SVEEEVIQNAEDERLASAVMSLPIKYREVIYLFYYEELSIKEIAEVTGVNENTVKTRLKKAKELLKK 173

                 ..
gi 489327667 183 QL 184
Cdd:PRK09415 174 GL 175
SigM_subfam TIGR02950
RNA polymerase sigma factor, SigM family; This family of RNA polymerase sigma factors is a ...
27-185 5.56e-27

RNA polymerase sigma factor, SigM family; This family of RNA polymerase sigma factors is a member of the Sigma-70 subfamily (TIGR02937) and is restricted to certain lineages of the order Bacillales. This family encompasses at least two distinct sigma factors as two proteins are found in each of B. anthracis, B. subtilis subsp. subtilis str. 168, and B. lichiniformis (although these are not apparently the same two in each). One of these is designated as SigM in B. subtilis (Swiss_Prot:


Pssm-ID: 274361 [Multi-domain]  Cd Length: 154  Bit Score: 99.84  E-value: 5.56e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667   27 YKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNIDSFDiNRKFSTWLYRIATNLTIDRIRKKKPDYYLDAEVAGTEGLTM 106
Cdd:TIGR02950   4 YMHDVFRYLYRLTKDKHLAEDLLQETFLKAYIHLHSFK-DSSIKPWLFRIARNAFIDWYRKDKKIQTIDDDAIGDLEQHP 82
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489327667  107 YSqivadgvLPEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKTRIHRGREALRKQLR 185
Cdd:TIGR02950  83 VE-------SPEHHLLIKIEQEEITHHLSRLPENYRTVLILREFKEFSYKEIAELLNLSLAKVKSNLFRARKELKKLLE 154
PRK12543 PRK12543
RNA polymerase sigma factor; Provisional
13-183 8.97e-27

RNA polymerase sigma factor; Provisional


Pssm-ID: 183582 [Multi-domain]  Cd Length: 179  Bit Score: 100.19  E-value: 8.97e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  13 KKGDQDAFADIVDIYKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATNlTIDRIRKKKPDY 92
Cdd:PRK12543   2 LSGDQEAFSEIYDVTIQEVYKTVHFLVEDKQDVDDVVNEIYIQLWESLRKYDSNRPFRFWLIGLVIK-QIHSWRRKRWRR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  93 YLDAEVAgteglTMYSQIVAdgVLPEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKTR 172
Cdd:PRK12543  81 FRIFEKA-----EEQRKPVS--IDFSEDVLSKESNQELIELIHKLPYKLRQVIILRYLHDYSQEEIAQLLQIPIGTVKSR 153
                        170
                 ....*....|.
gi 489327667 173 IHRGREALRKQ 183
Cdd:PRK12543 154 IHAALKKLRQK 164
PRK12522 PRK12522
RNA polymerase sigma factor; Provisional
23-184 3.11e-26

RNA polymerase sigma factor; Provisional


Pssm-ID: 183571 [Multi-domain]  Cd Length: 173  Bit Score: 98.40  E-value: 3.11e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  23 IVDIYKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATNLTIDRIRKKK--PDYYLDAEVAG 100
Cdd:PRK12522   8 LIDIYKQQIYSLCYKLAKTKEDAEDIFQETWIKVFSSRHQLSYVENYKKWITTICVRTFYDFYRKKKrwKDRILDLFHKE 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667 101 TEGLTMYSQivaDGVLPEDAVVSLElSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKTRIHRGREAL 180
Cdd:PRK12522  88 DGGEIEFAD---DVNISEEFIQKVE-AEMIREVIQLLNEKYKTVLVLYYYEQYSYKEMSEILNIPIGTVKYRLNYAKKQM 163

                 ....
gi 489327667 181 RKQL 184
Cdd:PRK12522 164 REHL 167
PRK12518 PRK12518
RNA polymerase sigma factor; Provisional
9-184 3.80e-25

RNA polymerase sigma factor; Provisional


Pssm-ID: 237124 [Multi-domain]  Cd Length: 175  Bit Score: 95.56  E-value: 3.80e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667   9 IKQVKKGDQDAFADIVDIYKDKIYQLCYRMLGnVHEAEDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATNLTIDRIRK- 87
Cdd:PRK12518   2 ILRCQRGDRQSFRQLYRRYQQKVRSTLYQLCG-RELLDDLVQEVFLRVWKGLPKLRNPAYFSTWLYRITWNVATDARRQf 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  88 -KKPDYyldaevagTEGLTMYSQIVADGVLPEdaVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPV 166
Cdd:PRK12518  81 aQRPSR--------IQDDSLNDQPSRPSDTPD--LMQLHYQDLVQQGLQTLSLEHRAVLVLHDLEDLPQKEIAEILNIPV 150
                        170
                 ....*....|....*...
gi 489327667 167 GTVKTRIHRGREALRKQL 184
Cdd:PRK12518 151 GTVKSRLFYARRQLRKFL 168
SigZ TIGR02959
RNA polymerase sigma factor, SigZ family; This family of RNA polymerase sigma factors is a ...
36-186 5.25e-25

RNA polymerase sigma factor, SigZ family; This family of RNA polymerase sigma factors is a member of the Sigma-70 subfamily (TIGR02937). One of these is designated as SigZ in B. subtilis (Swiss_Prot: SIGZ_BACSU). Interestingly, this group has a very sporatic distribution, B. subtilis, for instance, being the only sequenced strain of Bacilli with a member. Dechloromonas aromatica RCB appears to have two of these sigma factors. A member appears on a plasmid found in Photobacterium profundum SS9 and Vibrio fischeri ES114 (where a second one is chromosomally encoded).


Pssm-ID: 132004 [Multi-domain]  Cd Length: 170  Bit Score: 95.13  E-value: 5.25e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667   36 YRMLGNVHEAEDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATNLTIDRIRKKKPDYYLDAevagtegltmySQIVADGV 115
Cdd:TIGR02959  13 KSRVSDASDVEDLLQEVFIKIHRNLPSLKDGQKIQSWLYQIARNTIIDFYRSKSRSVELPE-----------SLLAADSA 81
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 489327667  116 LPEDAVVslELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKTRIHRGREALRKQLRD 186
Cdd:TIGR02959  82 REETFVK--ELSQCIPPMIKELPDEYREAIRLTELEGLSQQEIAEKLGLSLSGAKSRVQRGRKKLKELLET 150
PRK12519 PRK12519
RNA polymerase sigma factor; Provisional
12-187 1.61e-24

RNA polymerase sigma factor; Provisional


Pssm-ID: 237125 [Multi-domain]  Cd Length: 194  Bit Score: 94.74  E-value: 1.61e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  12 VKKGDQDAFADIVDIYKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNIdSFDINR-KFSTWLYRIATNLTIDRIRKKKP 90
Cdd:PRK12519  23 LKAGQSAALGVLYDRHAGLVYGLALKILGNSQEAEDLTQEIFLSLWRKS-SYDPKRgSLSSYLLTLTRSRAIDRLRSRRS 101
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  91 DYYLdAEVAGTEGLTMysqivADGVLPEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVK 170
Cdd:PRK12519 102 RQRL-LERWQQELLGE-----ASEDTPLEQASLAERSQRVQTALAQLPESQRQVLELAYYEGLSQSEIAKRLGIPLGTVK 175
                        170
                 ....*....|....*..
gi 489327667 171 TRIHRGREALRKQLRDL 187
Cdd:PRK12519 176 ARARQGLLKLRELLQDL 192
PRK08241 PRK08241
RNA polymerase subunit sigma-70;
15-181 2.45e-24

RNA polymerase subunit sigma-70;


Pssm-ID: 236196 [Multi-domain]  Cd Length: 339  Bit Score: 96.93  E-value: 2.45e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  15 GDQDAFADIVDIYKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATN--LTIDRIRKKKP-- 90
Cdd:PRK08241  16 GDRDAFAALVEPHRRELLAHCYRMLGSVHDAEDAVQETLLRAWRGYDRFEGRSSLRTWLYRIATNvcLDALEGRARRPlp 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  91 ----DYYLDAEVAGTE-----GLTMY--SQIVADGVLPEDAVV---SLELS--NTIQQkilkLPDKYRTVIVLKYIDELS 154
Cdd:PRK08241  96 tdlgAPAADPVDELVErpevpWLEPYpdALLDPAAADPAARVVareSVRLAfvAALQH----LPPRQRAVLILRDVLGWS 171
                        170       180
                 ....*....|....*....|....*..
gi 489327667 155 LIEIGEILNIPVGTVKTRIHRGREALR 181
Cdd:PRK08241 172 AAEVAELLDTSVAAVNSALQRARATLA 198
PRK12513 PRK12513
RNA polymerase sigma factor; Provisional
14-184 1.06e-23

RNA polymerase sigma factor; Provisional


Pssm-ID: 183566 [Multi-domain]  Cd Length: 194  Bit Score: 92.44  E-value: 1.06e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  14 KGDQDAFADIVDIYKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATNLTIDRIRKKKPDYY 93
Cdd:PRK12513  22 AGDAAAFEALYARHRTGLYRFLLRLARDRALAEDIFQETWLRVIRARAQYQPRARFRTWLYQIARNLLIDHWRRHGARQA 101
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  94 LDAEVAgtEGLTMYSqivADGVLPEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKTRI 173
Cdd:PRK12513 102 PSLDAD--EQLHALA---DDGAAPEQQLSLFRDRRRLQAALETLPDEQREVFLLREHGDLELEEIAELTGVPEETVKSRL 176
                        170
                 ....*....|.
gi 489327667 174 HRGREALRKQL 184
Cdd:PRK12513 177 RYALQKLRELL 187
Sig70_bacteroi1 TIGR02985
RNA polymerase sigma-70 factor, Bacteroides expansion family 1; This group of sigma factors ...
18-184 1.11e-23

RNA polymerase sigma-70 factor, Bacteroides expansion family 1; This group of sigma factors are members of the sigma-70 family (TIGR02937) and are found primarily in the genus Bacteroides. This family appears to have resulted from a lineage-specific expansion as B. thetaiotaomicron VPI-5482, Bacteroides forsythus ATCC 43037, Bacteroides fragilis YCH46 and Bacteroides fragilis NCTC 9343 contain 25, 12, 24 and 23 members, respectively. There are currentlyonly two known members of this family outside of the Bacteroides, in Rhodopseudomonas and Bradyrhizobium.


Pssm-ID: 274376 [Multi-domain]  Cd Length: 161  Bit Score: 91.47  E-value: 1.11e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667   18 DAFADIVDIYKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATNLTIDRIRKKK-----PDY 92
Cdd:TIGR02985   1 EAFEQLYRRYYPKLCAFARRYVKDEEDAEDIVQDVFLKLWENRETLEISESIKAYLFTIVKNRCLNYLRHKQveekyQEE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667   93 YLDAEVAGTEGLTMYSQIVADgvlpedavvslELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKTR 172
Cdd:TIGR02985  81 LAEIEERELSEADPEEELEAK-----------ELEEIIEEAIEKLPEQCREIFILSRFEGLSNKEIAEELGISVKTVEYH 149
                         170
                  ....*....|..
gi 489327667  173 IHRGREALRKQL 184
Cdd:TIGR02985 150 ITKALKFLRKEL 161
PRK09639 PRK09639
RNA polymerase sigma factor SigX; Provisional
16-184 1.17e-23

RNA polymerase sigma factor SigX; Provisional


Pssm-ID: 236602 [Multi-domain]  Cd Length: 166  Bit Score: 91.55  E-value: 1.17e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  16 DQDAFADIVDIYKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNidSFDINRKFSTWLYRIATNLTIDRIRKKKPDYyld 95
Cdd:PRK09639   1 SDETFEDLFEQYYPDVVQQIFYIVKDRTQAEDLAQEVFLRLYRS--DFKGIENEKGWLIKSARNVAYNYLRSEKRRR--- 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  96 aevAGTEGLTMYSQIVADGvLPEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDeLSLIEIGEILNIPVGTVKTRIHR 175
Cdd:PRK09639  76 ---ARILGEFQWQEVDNEP-SPEEIWIRKEEITKVQEVLAKMTERDRTVLLLRFSG-YSYKEIAEALGIKESSVGTTLAR 150

                 ....*....
gi 489327667 176 GREALRKQL 184
Cdd:PRK09639 151 AKKKFRKIY 159
PRK12514 PRK12514
RNA polymerase sigma factor; Provisional
5-184 1.25e-22

RNA polymerase sigma factor; Provisional


Pssm-ID: 105710 [Multi-domain]  Cd Length: 179  Bit Score: 89.11  E-value: 1.25e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667   5 IKKRIKQVKKGDQDAFADIVDIYKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNIDSFDIN-RKFSTWLYRIATNLTID 83
Cdd:PRK12514   6 IEKLIVRVSLGDRDAFSSLYDATSAKLFGICLRVLKDRSEAEEALQDVYVKIWTKADRFAVSgLSPMTWLITIARNHAID 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  84 RIRKKKPdyyldaevaGTEGLTMYSQIVADGVLPEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILN 163
Cdd:PRK12514  86 RLRARKA---------VAVDIDEAHDLADPSPGPEAEVIAGDEGQRIDACLEELEKDRAAAVRRAYLEGLSYKELAERHD 156
                        170       180
                 ....*....|....*....|.
gi 489327667 164 IPVGTVKTRIHRGREALRKQL 184
Cdd:PRK12514 157 VPLNTMRTWLRRSLLKLRECL 177
PRK09637 PRK09637
RNA polymerase sigma factor SigZ; Provisional
45-186 1.72e-22

RNA polymerase sigma factor SigZ; Provisional


Pssm-ID: 236601 [Multi-domain]  Cd Length: 181  Bit Score: 88.89  E-value: 1.72e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  45 AEDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATNLTIDRIRKKKPDYYLDAEVAGTEGltmysqivadgvlPEDAVVSL 124
Cdd:PRK09637  28 VDDLLQEVLIKTHSNLHSLKDGSSIKSWLYQIANNTIIDFYRKKNRSEELPDDLLFEDE-------------EREENAKK 94
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489327667 125 ELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKTRIHRGREALRKQLRD 186
Cdd:PRK09637  95 ELAPCLRPFIDALPEKYAEALRLTELEGLSQKEIAEKLGLSLSGAKSRVQRGRVKLKELLEG 156
PRK12538 PRK12538
RNA polymerase sigma factor; Provisional
15-185 6.34e-22

RNA polymerase sigma factor; Provisional


Pssm-ID: 139048 [Multi-domain]  Cd Length: 233  Bit Score: 88.76  E-value: 6.34e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  15 GDQDAFADIVDIYKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNIDSFDINR-KFSTWLYRIATNLTIDRIRKKKpdyy 93
Cdd:PRK12538  60 DDEAAFRLLVERHIDRAYAIALRIVGNRADAEDVVQDTMLKVWTHRGRWQHGRaKFSTWLYRVVSNRCIDLRRKPR---- 135
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  94 ldaevagTEGLTMYSQiVADGvlPEDAVVSL---ELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVK 170
Cdd:PRK12538 136 -------TENVDAVPE-VADG--KPDAVSVIernELSDLLEAAMQRLPEQQRIAVILSYHENMSNGEIAEVMDTTVAAVE 205
                        170
                 ....*....|....*
gi 489327667 171 TRIHRGREALRKQLR 185
Cdd:PRK12538 206 SLLKRGRQQLRDLLR 220
PRK12524 PRK12524
RNA polymerase sigma factor; Provisional
30-184 1.05e-21

RNA polymerase sigma factor; Provisional


Pssm-ID: 183573 [Multi-domain]  Cd Length: 196  Bit Score: 87.25  E-value: 1.05e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  30 KIYQLCYRMLGNVHEAEDIAQEAFIRAY-VNIDSFDINRKFSTWLYRIATNLTIDRIRKKKpdyyldaevAGTEGLTMYS 108
Cdd:PRK12524  38 RALAVATRVLGDRAEAEDVTQEAMLRLWrIAPDWRQGEARVSTWLYRVVCNLCTDRLRRRR---------RASVDLDDAP 108
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489327667 109 QIVADGVLPEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKTRIHRGREALRKQL 184
Cdd:PRK12524 109 EPADAAPGAEEALIEGDRMRALDAALAALPERQRQAVVLRHIEGLSNPEIAEVMEIGVEAVESLTARGKRALAALL 184
PRK09645 PRK09645
ECF RNA polymerase sigma factor SigL;
37-184 1.45e-21

ECF RNA polymerase sigma factor SigL;


Pssm-ID: 236605 [Multi-domain]  Cd Length: 173  Bit Score: 86.29  E-value: 1.45e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  37 RMLGNVHEAEDIAQEAFIRAYVNIDSF-DINRKFSTWLYRIATNLTID--RIRKKKPdyyldaEVAGTEGLTMYSQIVAD 113
Cdd:PRK09645  28 RLTGDRARAEDVVQETLLRAWQHPEVLaDTGRSARAWLFTVARNLVIDerRSARARP------VEGGDDVLGVPEQSAPD 101
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 489327667 114 GVlpEDAVVSLELSNTIQQkilkLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKTRIHRGREALRKQL 184
Cdd:PRK09645 102 EV--DRALDRLLVADALAQ----LSPEHRAVLVRSYYRGWSTAQIAADLGIPEGTVKSRLHYALRALRLAL 166
SigX5 TIGR02960
RNA polymerase sigma-70 factor, TIGR02960 family; This group of sigma factors are members of ...
15-184 1.34e-20

RNA polymerase sigma-70 factor, TIGR02960 family; This group of sigma factors are members of the sigma-70 family (TIGR02937). They and appear by homology, tree building, bidirectional best hits and one-to-a-genome distribution, to represent a conserved family.


Pssm-ID: 132005 [Multi-domain]  Cd Length: 324  Bit Score: 86.84  E-value: 1.34e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667   15 GDQDAFADIVDIYKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATNLTIDRIRKKK----- 89
Cdd:TIGR02960   2 VDGAAFTALAEPHRRELLAHCYRMLGSLHEAEDLVQETLLRAWRARDRFEGRSSVRTWLYRIATNACLDALEARQrrprp 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667   90 ---PDYYLDAEVAGTEG-----LTMYSQIVADGVLPE--DAVVSLELSNTIQ----QKILKLPDKYRTVIVLKYIDELSL 155
Cdd:TIGR02960  82 vglGAPSADGTAAASEAaevtwLEPLPDLTLDLDDPAaaDPSVAAGSRESVRlafvAAIQYLPPRQRAVLLLRDVLGWRA 161
                         170       180
                  ....*....|....*....|....*....
gi 489327667  156 IEIGEILNIPVGTVKTRIHRGREALRKQL 184
Cdd:TIGR02960 162 AETAELLGTSTASVNSALQRARATLDEVG 190
Sigma70_r2 pfam04542
Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. ...
23-89 4.29e-20

Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. All members of this class of sigma-factor contain region 2. The high conservation is due to region 2 containing both the -10 promoter recognition helix and the primary core RNA polymerase binding determinant. The core binding helix, interacts with the clamp domain of the largest polymerase subunit, beta prime. The aromatic residues of the recognition helix, found at the C-terminus of this domain are though to mediate strand separation, thereby allowing transcription initiation.


Pssm-ID: 427998 [Multi-domain]  Cd Length: 71  Bit Score: 79.55  E-value: 4.29e-20
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489327667   23 IVDIYKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNIDSFDINR--KFSTWLYRIATNLTIDRIRKKK 89
Cdd:pfam04542   1 LVERYLPLVYSLARRYLGDGADAEDLVQEGFLGLWRAIERFDPERgvSFSTWLYTIIRNAIIDYLRKQR 69
PRK09644 PRK09644
RNA polymerase sigma factor SigM; Provisional
22-186 8.27e-20

RNA polymerase sigma factor SigM; Provisional


Pssm-ID: 170033 [Multi-domain]  Cd Length: 165  Bit Score: 81.46  E-value: 8.27e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  22 DIVDIYKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNIDSFDiNRKFSTWLYRIATNLTIDRIRKKKPDYYLDAEVAGT 101
Cdd:PRK09644   5 EIYKMYINDVYRYLFSLTKSHHAAEDLLQETFYRAYIYLEDYD-NQKVKPWLFKVAYHTFIDFVRKEKKVSFVGTDEIEA 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667 102 EGLTMysqivadgvlPEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKTRIHRGREALR 181
Cdd:PRK09644  84 IQAES----------TEEYVVAKNSYEKLIQIIHTLPVIEAQAILLCDVHELTYEEAASVLDLKLNTYKSHLFRGRKRLK 153

                 ....*
gi 489327667 182 KQLRD 186
Cdd:PRK09644 154 ALLKE 158
PRK12515 PRK12515
RNA polymerase sigma factor; Provisional
9-187 2.12e-19

RNA polymerase sigma factor; Provisional


Pssm-ID: 183567 [Multi-domain]  Cd Length: 189  Bit Score: 80.93  E-value: 2.12e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667   9 IKQVKKGDQDAFADIVDIYKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATNLTIDRIRKK 88
Cdd:PRK12515  13 LARIAQGDRTAMQTLYGRHHVRVYRFGLRLVRDEQTAEDLVSEVFLDVWRQAGQFEGRSQVSTWLLSIARFKALSALRRR 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  89 KpDYYLDAEVAGTegltmysqiVADGV-LPEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVG 167
Cdd:PRK12515  93 K-HEEIDDEAAAA---------IEDGAdTPEVALQKSDTSAALRACLAKLSPAHREIIDLVYYHEKSVEEVGEIVGIPES 162
                        170       180
                 ....*....|....*....|
gi 489327667 168 TVKTRIHRGrealRKQLRDL 187
Cdd:PRK12515 163 TVKTRMFYA----RKKLAEL 178
PRK12533 PRK12533
RNA polymerase sigma factor; Provisional
20-180 4.02e-19

RNA polymerase sigma factor; Provisional


Pssm-ID: 237129 [Multi-domain]  Cd Length: 216  Bit Score: 80.93  E-value: 4.02e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  20 FADIVDIYKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNIDSF--DINRkfsTWLYRIATNLTIDRIRKKKPDY---YL 94
Cdd:PRK12533  20 FRQLVLPHLDAAYNLARWLCGNASDADDVVQEACMRALRFFDSFrgDNAR---PWLLAIVRHTWYSEWRRRANAHevaAP 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  95 DaEVAGTEGLTMYSQIVADgvlPEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKTRIH 174
Cdd:PRK12533  97 D-TLDDADSLDDWQPAGED---PLALLLRAEDVRLVNAALAKLPVEYREVLVLRELEDMSYREIAAIADVPVGTVMSRLA 172

                 ....*.
gi 489327667 175 RGREAL 180
Cdd:PRK12533 173 RARRRL 178
PRK12531 PRK12531
RNA polymerase sigma factor; Provisional
9-181 1.37e-18

RNA polymerase sigma factor; Provisional


Pssm-ID: 105726 [Multi-domain]  Cd Length: 194  Bit Score: 79.20  E-value: 1.37e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667   9 IKQVKKGDQDAFADIVDIYKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNIDSFDINRK-FSTWLYRIATNLTIDRIRK 87
Cdd:PRK12531  18 MEKVKSRDKQAFALVFSYYAPKLKQFAMKHVGNEQVAMEMVQETMSTVWQKAHLFDGQKSaLSTWIYTIIRNLCFDLLRK 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  88 KKpdyyldaevagteGLTMYsqIVADGVLPEDaVVSLELSN--TIQQKILK---------LPDKYRTVIVLKYIDELSLI 156
Cdd:PRK12531  98 QK-------------GKDLH--IHADDIWPSD-YYPPDLVDhySPEQDMLKeqvmkfldrLPKAQRDVLQAVYLEELPHQ 161
                        170       180
                 ....*....|....*....|....*
gi 489327667 157 EIGEILNIPVGTVKTRIHRGREALR 181
Cdd:PRK12531 162 QVAEMFDIPLGTVKSRLRLAVEKLR 186
PRK09646 PRK09646
ECF RNA polymerase sigma factor SigK;
9-186 6.99e-18

ECF RNA polymerase sigma factor SigK;


Pssm-ID: 182015 [Multi-domain]  Cd Length: 194  Bit Score: 77.02  E-value: 6.99e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667   9 IKQVKKGDQDAFADIVDIYKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNIDSFDINR-KFSTWLYRIATNLTIDRIRk 87
Cdd:PRK09646  21 LRRVARGDQDAFAELYDRTSSRVYGLVRRVLRDPGYSEETTQEVYLEVWRTASRFDPARgSALAWLLTLAHRRAVDRVR- 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  88 kkpdyyldAEVAGTEGLTMYSQIVADG---VLPEDAVVSLElsntiQQKIL----KLPDKYRTVIVLKYIDELSLIEIGE 160
Cdd:PRK09646 100 --------SEQAASQREVRYGARNVDPafdQVAEEVEARLE-----RERVRdcldALTDTQRESVTLAYYGGLTYREVAE 166
                        170       180
                 ....*....|....*....|....*.
gi 489327667 161 ILNIPVGTVKTRIhrgREALRKqLRD 186
Cdd:PRK09646 167 RLAVPLGTVKTRM---RDGLIR-LRD 188
PRK09640 PRK09640
RNA polymerase sigma factor SigX; Reviewed
16-187 8.09e-18

RNA polymerase sigma factor SigX; Reviewed


Pssm-ID: 236603 [Multi-domain]  Cd Length: 188  Bit Score: 76.90  E-value: 8.09e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  16 DQDAFADIVDIYKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATNLTIDRIRKKKPDYYLd 95
Cdd:PRK09640  24 VTRAYEELMRRYQRTLFNVCARYLGNDRDADDVCQEVMLKVLYGLKNFEGKSKFKTWLYSITYNECITQYRKERRKRRL- 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  96 aevagTEGLTMYSQIVADgvlpEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKTRIHR 175
Cdd:PRK09640 103 -----MDALSLDPLEEAS----EEKAPKPEERGGLDRWLVHVNPIDREILVLRFVAELEFQEIADIMHMGLSATKMRYKR 173
                        170
                 ....*....|..
gi 489327667 176 GREALRKQLRDL 187
Cdd:PRK09640 174 ALDKLREKFAGL 185
PRK12511 PRK12511
RNA polymerase sigma factor; Provisional
41-181 2.81e-17

RNA polymerase sigma factor; Provisional


Pssm-ID: 237123 [Multi-domain]  Cd Length: 182  Bit Score: 75.21  E-value: 2.81e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  41 NVHEAEDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATNLTIDRIRKKKPDYYLDAEVAgtegltmysqIVADGVLP--E 118
Cdd:PRK12511  27 DSAEAEDLVHDALVRALERRASFRSGGNLRTWLMSILHNAFIDELRRRRVEARRADELA----------VLADASLPaaQ 96
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489327667 119 DAVVSLElsnTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKTRIHRGREALR 181
Cdd:PRK12511  97 EHAVRLA---QIRDAFFDLPEEQRAALHLVAIEGLSYQEAAAVLGIPIGTLMSRIGRARAALR 156
PRK06811 PRK06811
RNA polymerase factor sigma-70; Validated
9-182 2.35e-16

RNA polymerase factor sigma-70; Validated


Pssm-ID: 180707 [Multi-domain]  Cd Length: 189  Bit Score: 73.05  E-value: 2.35e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667   9 IKQVKKGDQDAFADIVDIYKDKIYQLCYRMLGNVHEAEDI---AQEAFIRAYVNIDSFDINR-KFSTWLYRIATNLTIDR 84
Cdd:PRK06811   9 IKELKKKNEKALEFIVDTYGNLVKKIVHKVLGTVNYSQLIeecVNDIFLSIWNNIDKFDEEKgSFKKWIAAISKYKAIDY 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  85 IRKKKPDYYLDAEvagtegltmYSQIVADGVLPEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNI 164
Cdd:PRK06811  89 KRKLTKNNEIDSI---------DEFILISEESIENEIILKENKEEILKLINDLEKLDREIFIRRYLLGEKIEEIAKKLGL 159
                        170
                 ....*....|....*...
gi 489327667 165 PVGTVKTRIHRGREALRK 182
Cdd:PRK06811 160 TRSAIDNRLSRGRKKLQK 177
PRK09642 PRK09642
RNA polymerase sigma factor;
27-186 1.05e-15

RNA polymerase sigma factor;


Pssm-ID: 170031 [Multi-domain]  Cd Length: 160  Bit Score: 70.90  E-value: 1.05e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  27 YKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNIDSFDInRKFSTWLYRIATNLTIDRIRKKKPDYYLDAEVAGTEGLTM 106
Cdd:PRK09642   4 YRHYIFQVIFSILRHEEDAKDVTQEVFVKIHASLPNYQF-RGLKTWMARIATNHAIDYKRKKARENEELSLCKETEENIK 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667 107 YSQIVadgvlpEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKTRIHRGREALRKQLRD 186
Cdd:PRK09642  83 SSHNI------EDLLLTKEQKLLIAQKLRELPENYRDVVLAHYLEEKSYQEIALQEKIEVKTVEMKLYRARKWIKKHWKE 156
PRK12517 PRK12517
RNA polymerase sigma factor; Provisional
17-184 1.37e-15

RNA polymerase sigma factor; Provisional


Pssm-ID: 183569 [Multi-domain]  Cd Length: 188  Bit Score: 70.87  E-value: 1.37e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  17 QDAFADIVDIYKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATNLTIDRIRKKKPDYyLDA 96
Cdd:PRK12517  22 QRRYEALVKALHADIYRYAYWLCKDKHIAEDLVQETFLRAWRSLDSLKDEKAAKAWLITILRRENARRFERKQFDL-VDI 100
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  97 EVAGTEGLTMYSqivadgvlPEDavvslELSNT-IQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKTRIHR 175
Cdd:PRK12517 101 EDDSIEDDASHS--------SEE-----EMEQEwLRRQIAKLDPEYREPLLLQVIGGFSGEEIAEILDLNKNTVMTRLFR 167

                 ....*....
gi 489327667 176 GREALRKQL 184
Cdd:PRK12517 168 ARNQLKEAL 176
Sigma70_r4 cd06171
Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in ...
130-181 1.37e-15

Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or plastid core RNA polymerase to specific promoter elements located upstream of transcription initiation points. The SR4 of Ec sigma70 and other essential primary SFs contact promoter sequences located 35 base-pairs upstream of the initiation point, recognizing a 6-base-pair -35 consensus TTGACA. Sigma70 related SFs also include SFs which are dispensable for bacterial cell growth for example Ec sigmaS, SFs which activate regulons in response to a specific signal for example heat-shock Ec sigmaH, and a group of SFs which includes the extracytoplasmic function (ECF) SFs and is typified by Ec sigmaE which contains SR2 and -4 only. ECF SFs direct the transcription of genes that regulate various responses including periplasmic stress and pathogenesis. Ec sigmaE SR4 also contacts the -35 element, but recognizes a different consensus (a 7-base-pair GGAACTT). Plant SFs recognize sigma70 type promoters and direct transcription of the major plastid RNA polymerase, plastid-encoded RNA polymerase (PEP).


Pssm-ID: 100119 [Multi-domain]  Cd Length: 55  Bit Score: 67.51  E-value: 1.37e-15
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 489327667 130 IQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKTRIHRGREALR 181
Cdd:cd06171    4 LEEALDKLPEREREVILLRFGEGLSYEEIAEILGISRSTVRQRLHRALKKLR 55
Sigma70_r4_2 pfam08281
Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 ...
130-180 2.66e-13

Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 promoter element via a helix-turn-helix motif.


Pssm-ID: 400535 [Multi-domain]  Cd Length: 54  Bit Score: 61.32  E-value: 2.66e-13
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 489327667  130 IQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKTRIHRGREAL 180
Cdd:pfam08281   4 LLRALEELPPRQREVFLLRYLEGLSYAEIAELLGISEGTVKSRLSRARKKL 54
Sig-70_gvs1 TIGR02989
RNA polymerase sigma-70 factor, Rhodopirellula/Verrucomicrobium family; This group of sigma ...
18-181 2.73e-13

RNA polymerase sigma-70 factor, Rhodopirellula/Verrucomicrobium family; This group of sigma factors are members of the sigma-70 family (TIGR02937) and are abundantly found in the species Rhodopirellula baltica (11), and Verrucomicrobium spinosum (16) and to a lesser extent in Gemmata obscuriglobus (2).


Pssm-ID: 274379 [Multi-domain]  Cd Length: 159  Bit Score: 64.26  E-value: 2.73e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667   18 DAFADIVDIYKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATNLTIDRIRKKKPDYYL-DA 96
Cdd:TIGR02989   1 KAFVRLLTRHERALRAFVRSLVADRDDVDDVLQETFVVAWRKFDQFDPGTNFVAWARGIARNKVLNYRRKLGRDRLVfDD 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667   97 EVagtegltmySQIVADGVLPEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKTRIHRG 176
Cdd:TIGR02989  81 DL---------LEALAAEAEPTEAERLSDDRQALEGCLEKLPERQRELLDLRYQRGQKATALAEQTGRTVNAVYKALQRI 151

                  ....*
gi 489327667  177 REALR 181
Cdd:TIGR02989 152 RVSLR 156
PRK12540 PRK12540
RNA polymerase sigma factor; Provisional
40-184 5.24e-13

RNA polymerase sigma factor; Provisional


Pssm-ID: 183579 [Multi-domain]  Cd Length: 182  Bit Score: 64.22  E-value: 5.24e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  40 GNVHEAEDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATNLTIDRIRKKKPDYYlDAEvaGTEGLTMYSQIVADGVLP-E 118
Cdd:PRK12540  27 GNGDRADDLVQETLLRALANIDSFQPGSNLPAWLFTILRNLFRSDYRKRRREVE-DAD--GSYAKTLKSQPGQNAHLEfE 103
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489327667 119 DAVVSLElsntiqqkilKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKTRIHRGREALRKQL 184
Cdd:PRK12540 104 EFRAALD----------KLPQDQREALILVGASGFSYEDAAAICGCAVGTIKSRVNRARSKLSALL 159
PRK09636 PRK09636
RNA polymerase sigma factor SigJ; Provisional
15-86 1.03e-12

RNA polymerase sigma factor SigJ; Provisional


Pssm-ID: 236600 [Multi-domain]  Cd Length: 293  Bit Score: 64.56  E-value: 1.03e-12
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489327667  15 GDQDAFADIVDIYKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYvNIDSFDInRKFSTWLYRIATNLTIDRIR 86
Cdd:PRK09636   1 MTMADAAAEFEPLRPHLLSVAYRMLGSVADAEDIVQEAWLRWN-NADRAQI-RDPRAWLTRVVTRLCLDRLR 70
PRK12516 PRK12516
RNA polymerase sigma factor; Provisional
38-185 3.14e-12

RNA polymerase sigma factor; Provisional


Pssm-ID: 183568 [Multi-domain]  Cd Length: 187  Bit Score: 61.90  E-value: 3.14e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  38 MLGNVHEAEDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATNLTIDRIRKKkpdyylDAEVAGTEGltMYSQIVAdgVLP 117
Cdd:PRK12516  30 LIGRHDRADDLVQDTIMKAWAKQDHFEVGTNMKAWLFTILRNEFYSQMRKR------GREVQDTDG--MFTEQLA--VHP 99
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489327667 118 EDaVVSLELSNtIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKTRIHRGREALRKQLR 185
Cdd:PRK12516 100 SQ-YGTLDLQD-FRAALDQLPDDQREAIILVGASGFAYEEAAEICGCAVGTIKSRVNRARQRLQEILQ 165
PRK13919 PRK13919
putative RNA polymerase sigma E protein; Provisional
12-186 3.93e-12

putative RNA polymerase sigma E protein; Provisional


Pssm-ID: 184395 [Multi-domain]  Cd Length: 186  Bit Score: 61.85  E-value: 3.93e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  12 VKKGDQDAFADIVDIYKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNIDSFDINRKFS-TWLYRIATNLTIDRIRKK-- 88
Cdd:PRK13919  17 VARGEEEALRALFRRYAGAFLALARRMGLDGAAAEDVVQEVFIRVWKKAKEFDPRRGSArAWLLALAHHAAVDHVRRRaa 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  89 KPDyYLDAEVAGTEGLtmysQIVADGVLPEDAVVSLELsntiQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGT 168
Cdd:PRK13919  97 RPQ-PLEPDEREPEAF----DLPGPGLDEEGHLDRTRL----GRALKALSPEERRVIEVLYYQGYTHREAAQLLGLPLGT 167
                        170
                 ....*....|....*...
gi 489327667 169 VKTRIHRGREALRKQLRD 186
Cdd:PRK13919 168 LKTRARRALSRLKEVLRE 185
PRK12541 PRK12541
RNA polymerase sigma factor; Provisional
25-182 8.24e-12

RNA polymerase sigma factor; Provisional


Pssm-ID: 183580 [Multi-domain]  Cd Length: 161  Bit Score: 60.34  E-value: 8.24e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  25 DIYKDKIYQLCYRML---GNVHEAEDIAQEAFIRAYVNIDSFDiNRKFSTWLYRIATNLTIDRIRKKKPdyYLDAEVAGT 101
Cdd:PRK12541   9 EIYSEHMQDLFRYLLsltGDSHFAEDLMQETFYRMLVHIDYYK-GEEIRPWLFTIAYNAFIDWYRKEKK--YKTTTIEEF 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667 102 EgltmysqivadgvLPEdaVVSLELSNTIQQKIL-------KLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKTRIH 174
Cdd:PRK12541  86 H-------------LPN--VPSTEHEYFIKHEIAswldslsSLPLERRNVLLLRDYYGFSYKEIAEMTGLSLAKVKIELH 150

                 ....*...
gi 489327667 175 RGREALRK 182
Cdd:PRK12541 151 RGRKETKS 158
PRK12546 PRK12546
RNA polymerase sigma factor; Provisional
41-184 9.70e-12

RNA polymerase sigma factor; Provisional


Pssm-ID: 139055 [Multi-domain]  Cd Length: 188  Bit Score: 60.62  E-value: 9.70e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  41 NVHEAEDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATNLTIDRIRKKKpdyyldAEVAGTEGLTMYSQIVA---DGVLP 117
Cdd:PRK12546  30 NVAVADDLVQDTIVKAWTNFDKFQEGTNLRAWLFTILRNTFYSDRRKHK------REVPDPEGVHAASLAVKpahDGRLA 103
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489327667 118 EDavvslELSNTIQQkilkLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKTRIHRGREALRKQL 184
Cdd:PRK12546 104 MS-----DFRAAFAQ----LPDEQREALILVGASGFSYEEAAEMCGVAVGTVKSRANRARARLAELL 161
PRK12537 PRK12537
RNA polymerase sigma factor; Provisional
14-181 1.10e-11

RNA polymerase sigma factor; Provisional


Pssm-ID: 171568 [Multi-domain]  Cd Length: 182  Bit Score: 60.56  E-value: 1.10e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  14 KGDQDAFADIVDIYKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNIDSFDINRKFST-WLYRIATNLTIDRIRKKKPDY 92
Cdd:PRK12537  19 RGDRRALQALYQQESARLLGVARRIVRDRALAEDIVHDAFIKIWTGAASFDPARGSARgWIYSVTRHLALNVLRDTRREV 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  93 YLDAEvaGTEGLTMYSQIVADgvlpEDAVVSlelSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKTR 172
Cdd:PRK12537  99 VLDDD--AEETAQTLHEIIDD----FDLWAN---SGKIHRCLEQLEPARRNCILHAYVDGCSHAEIAQRLGAPLGTVKAW 169

                 ....*....
gi 489327667 173 IHRGREALR 181
Cdd:PRK12537 170 IKRSLKALR 178
PRK12544 PRK12544
RNA polymerase factor sigma-70;
39-186 3.13e-11

RNA polymerase factor sigma-70;


Pssm-ID: 183583 [Multi-domain]  Cd Length: 206  Bit Score: 59.82  E-value: 3.13e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  39 LGNVHEAEDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATNLTIDRIRKKKPDYYLDAEVAGTEGLTMYSQIV-ADG--- 114
Cdd:PRK12544  39 LSDLHLAEDAVQEALIGALKNADSFAGRAAFKTWVFAILKNKIIDLLRQKKRHVSASSLLRDEEEEEDFEELFdESGhwq 118
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667 115 --------VLPEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKTRIHRGREALRKQLRD 186
Cdd:PRK12544 119 kderpqawGNPEESLEQEQFWRIFEACLDGLPAKYARVFMMREFIELETNEICHAVDLSVSNLNVLLYRARLRLRECLEN 198
PRK12539 PRK12539
RNA polymerase sigma factor SigF;
44-180 4.66e-11

RNA polymerase sigma factor SigF;


Pssm-ID: 237132 [Multi-domain]  Cd Length: 184  Bit Score: 58.59  E-value: 4.66e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  44 EAEDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATNLTIDRIRKkkpdyyldaevagTEGLTMYSQIV-ADGVLPEDAVV 122
Cdd:PRK12539  51 EAEDLVQEALMAIHTRRHTYDPEQPLTPWVYAIARYKLIDHLRR-------------TRASLADVPIDdADELVAHDDHA 117
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 489327667 123 SLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKTRIHRGREAL 180
Cdd:PRK12539 118 AVESTLDLGRLLARLPEKMRLAIQAVKLEGLSVAEAATRSGMSESAVKVSVHRGLKAL 175
Sigma70_r4 pfam04545
Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 ...
136-182 7.20e-11

Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 promoter element via a helix-turn-helix motif. Due to the way Pfam works, the threshold has been set artificially high to prevent overlaps with other helix-turn-helix families. Therefore there are many false negatives.


Pssm-ID: 461347 [Multi-domain]  Cd Length: 50  Bit Score: 54.74  E-value: 7.20e-11
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 489327667  136 KLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKTRIHRGREALRK 182
Cdd:pfam04545   4 SLPPRERQVLVLRYGEGLTLEEIGERLGISRERVRQIEKRALRKLRK 50
PRK12547 PRK12547
RNA polymerase sigma factor; Provisional
38-185 1.52e-10

RNA polymerase sigma factor; Provisional


Pssm-ID: 139056 [Multi-domain]  Cd Length: 164  Bit Score: 57.19  E-value: 1.52e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  38 MLGNVHEAEDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATNLTIDRIRKKKpdyyldAEVAGTEGLtmYSQIVAdgvLP 117
Cdd:PRK12547  26 LSSKHDKAEDLVQDTLMKAWAKQDSFEMGTNLKAWLFTILRNEFYSQMRKRG------REVQDSDGV--FTARVA---VH 94
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489327667 118 EDAVVSLELsNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKTRIHRGREALRKQLR 185
Cdd:PRK12547  95 PAQYGSLDL-QDFKKALNLLSADQREAIILIGASGFSYEDAAAICGCAVGTIKSRVSRARNRLQELLK 161
PRK12534 PRK12534
RNA polymerase sigma factor; Provisional
15-184 1.62e-10

RNA polymerase sigma factor; Provisional


Pssm-ID: 183576 [Multi-domain]  Cd Length: 187  Bit Score: 57.37  E-value: 1.62e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  15 GDQDAFADIVDIYKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNIDSFDINR-KFSTWLYRIATNLTIDRIRKKKPDyy 93
Cdd:PRK12534  22 GDRHAFEALYRQTSPKLFGVCLRMIPQRAEAEEVLQDVFTLIWHKAGQFDPSRaRGLTWLAMIARNKAIDHLRANAPQ-- 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  94 lDAEVAGTEGltmysqivadGVLPEDAVVSLELSN------TIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVG 167
Cdd:PRK12534 100 -RRNVALDDA----------GELRAADASPLERTErastrrRIDHCLAELEPPRSELIRTAFFEGITYEELAARTDTPIG 168
                        170
                 ....*....|....*..
gi 489327667 168 TVKTRIHRGREALRKQL 184
Cdd:PRK12534 169 TVKSWIRRGLAKLKACL 185
PRK12526 PRK12526
RNA polymerase sigma factor; Provisional
16-186 1.76e-10

RNA polymerase sigma factor; Provisional


Pssm-ID: 237127 [Multi-domain]  Cd Length: 206  Bit Score: 57.50  E-value: 1.76e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  16 DQDAFADIVDIYKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNIDSFDINR-KFSTWLYRIATNLTIDRIRKKKpdyyl 94
Cdd:PRK12526  36 DKQAFTHLFQFFAPKIKRFGIKQLGNEAQANELVQETMSNVWRKAHLYNGDKgAATTWVYTVMRNAAFDMLRKIK----- 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  95 daevagteglTMYSQIVADGVLP-EDAVV-----SLELSNTIQQK-----ILKLPDKYRTVIVLKYIDELSLIEIGEILN 163
Cdd:PRK12526 111 ----------AKKEQNLGDDIWPiEQALAesqseSEEFSDHLMDKqilsyIEKLPEAQQTVVKGVYFQELSQEQLAQQLN 180
                        170       180
                 ....*....|....*....|...
gi 489327667 164 IPVGTVKTRIHRGREALRKQLRD 186
Cdd:PRK12526 181 VPLGTVKSRLRLALAKLKVQMGE 203
PRK09649 PRK09649
RNA polymerase sigma factor SigC; Reviewed
14-180 2.86e-10

RNA polymerase sigma factor SigC; Reviewed


Pssm-ID: 137458 [Multi-domain]  Cd Length: 185  Bit Score: 56.59  E-value: 2.86e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  14 KGDQDAFADIVDIYKDKIYQLCyRMLGNVHEAEDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATNLTIDRIR--KKKPD 91
Cdd:PRK09649  20 KGNGRALEAFIKATQQDVWRFV-AYLSDVGSADDLTQETFLRAIGAIPRFSARSSARTWLLAIARHVVADHIRhvRSRPR 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  92 YYLDaevaGTEGLTMYSQIVADGVlpEDAVvslELSNTIQQkilkLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKT 171
Cdd:PRK09649  99 TTRG----ARPEHLIDGDRHARGF--EDLV---EVTTMIAD----LTTDQREALLLTQLLGLSYADAAAVCGCPVGTIRS 165

                 ....*....
gi 489327667 172 RIHRGREAL 180
Cdd:PRK09649 166 RVARARDAL 174
SigX4 TIGR02957
RNA polymerase sigma-70 factor, TIGR02957 family; This group of sigma factors are members of ...
27-181 5.81e-10

RNA polymerase sigma-70 factor, TIGR02957 family; This group of sigma factors are members of the sigma-70 family (TIGR02937). They and appear by homology, tree building and bidirectional best hits, to represent a conserved family. This family is found in a limited number of bacterial lineages. This family includes apparent paralogous expansion in Streptomyces coelicolor A3(2), and multiple copies in Mycobacterium smegmatis MC2, Streptomyces avermitilis MA-4680 and Nocardia farcinica IFM10152.


Pssm-ID: 132002 [Multi-domain]  Cd Length: 281  Bit Score: 56.98  E-value: 5.81e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667   27 YKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYvNIDSFDINRKFStWLYRIATNLTIDRI---RKKKPDY---YLDAEVAG 100
Cdd:TIGR02957   6 LRPLLFSLAYRMLGSVADAEDIVQETFLRWQ-EADRAQIENPKA-YLTKVVTRRCIDVLrsaRARREVYvgpWLPEPLLT 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  101 TegltmySQIVADGVLPEDAvVSLELSNTIQQkilkLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKTRIHRGREAL 180
Cdd:TIGR02957  84 T------SADPAESVELAES-LSMAYLLLLER----LSPLERAVFVLREVFDYPYEEIASIVGKSEANCRQLVSRARRHL 152

                  .
gi 489327667  181 R 181
Cdd:TIGR02957 153 D 153
PRK12532 PRK12532
RNA polymerase sigma factor; Provisional
45-184 1.01e-09

RNA polymerase sigma factor; Provisional


Pssm-ID: 171564 [Multi-domain]  Cd Length: 195  Bit Score: 55.32  E-value: 1.01e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  45 AEDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATNLTIDRIRKK----KPDYYLDAEVAGTEGLTMYSQIV--------A 112
Cdd:PRK12532  33 AEDLVQETLLSAYSAGDSFQGRALVNSWLFAILKNKIIDALRQIgrqrKVFTLLDDELLDEAFESHFSQNGhwtpegqpQ 112
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489327667 113 DGVLPEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKTRIHRGREALRKQL 184
Cdd:PRK12532 113 HWNTPEKSLNNNEFQKILQSCLYNLPENTARVFTLKEILGFSSDEIQQMCGISTSNYHTIMHRARESLRQCL 184
PRK09648 PRK09648
RNA polymerase sigma factor ShbA;
15-184 1.34e-09

RNA polymerase sigma factor ShbA;


Pssm-ID: 236607 [Multi-domain]  Cd Length: 189  Bit Score: 54.98  E-value: 1.34e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  15 GDQDAFADIVDIYKDKIYQLCYRMLGNV----HEAEDIAQEAFIRAYVNIDSF-DINRKFSTWLYRIATNLTIDRIRKK- 88
Cdd:PRK09648  21 GDRRALREVLEIIRPLVVRYCRARLGGVerpgLSADDVAQEVCLAVITALPRYrDQGRPFLAFVYGIAAHKVADAHRAAg 100
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  89 KPDYYLDAEVAGTEgltmysqivADGVLPEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGT 168
Cdd:PRK09648 101 RDKAVPTEEVPERP---------SDDAGPEERALRSESSNRMRELLDTLPEKQREILILRVVVGLSAEETAEAVGSTPGA 171
                        170
                 ....*....|....*.
gi 489327667 169 VKTRIHRGREALRKQL 184
Cdd:PRK09648 172 VRVAQHRALARLRAEI 187
Sig70_famx1 TIGR02943
RNA polymerase sigma-70 factor, TIGR02943 family; This group of sigma factors are members of ...
45-184 4.59e-09

RNA polymerase sigma-70 factor, TIGR02943 family; This group of sigma factors are members of the sigma-70 family (TIGR02937). They and appear by homology, tree building, bidirectional best hits and one-to-a-genome distribution, to represent a conserved family.


Pssm-ID: 274359 [Multi-domain]  Cd Length: 188  Bit Score: 53.23  E-value: 4.59e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667   45 AEDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATNLTIDRIRKKKPD---YYLDAEVAGTEGLTMYSQ--------IVAD 113
Cdd:TIGR02943  29 AEDAVQETLLAALSHRDSFAGRSALKTWLFAILKNKIIDALRAKGREvkvSDLDDELDDEAFNALFTQnghwaqhgQPQH 108
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 489327667  114 GVLPEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKTRIHRGREALRKQL 184
Cdd:TIGR02943 109 WNTPEKQLENKEFWEVFEACLYHLPEQTARVFMMREVLGFESDEICQELEISTSNCHVLLYRARLSLRACL 179
FliA COG1191
DNA-directed RNA polymerase specialized sigma subunit [Transcription]; DNA-directed RNA ...
5-186 1.06e-08

DNA-directed RNA polymerase specialized sigma subunit [Transcription]; DNA-directed RNA polymerase specialized sigma subunit is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 440804 [Multi-domain]  Cd Length: 236  Bit Score: 52.90  E-value: 1.06e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667   5 IKKRIKQVKKGDQDAFADIVDIYKDKIYQLCYRMLGNVH-EAEDIAQ---EAFIRAyvnIDSFDINR--KFSTW-LYRI- 76
Cdd:COG1191    2 LEELLRRYQEGDEEAREELIEEYLPLVKKIASRLAGRLPaELDDLIQvglIGLIEA---IDRFDPSKgvSFETYaVPRIr 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  77 ----------------------ATNLTIDRIRKKKPDYYLDAEVAGTEGLTM--YSQIVADGVL---------------- 116
Cdd:COG1191   79 gaildylrdedwvprsvrelarKIEEAIEELEQELGREPTDEEIAEELGISLeeVQEALEAANAyqllsldepledgddl 158
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489327667 117 --------PEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVkTRIH-RGREALRKQLRD 186
Cdd:COG1191  159 ldllesgdPEEELEHEELREALAEAIEQLPERERLVLSLYYFEELTLKEIAEVLGVSESRV-SRLHkKALARLREYLKE 236
PRK12527 PRK12527
RNA polymerase sigma factor; Reviewed
27-185 1.59e-08

RNA polymerase sigma factor; Reviewed


Pssm-ID: 171560 [Multi-domain]  Cd Length: 159  Bit Score: 51.31  E-value: 1.59e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  27 YKDKIYQLCYRmLGNVHEAEDIAQEAFIRAYVNIDSFDIN--RKFstwLYRIATNLTIDR-----IRKKKPDYYLDAEva 99
Cdd:PRK12527   5 YRELVRFLSAR-LGNRQAAEDVAHDAYLRVLERSSSAQIEhpRAF---LYRTALNLVVDRhrrhrVRQAEPLEVLDEE-- 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667 100 gtEGLTMYSQIVAdgvlpEDAVVSLELsntIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKTRIHRGREA 179
Cdd:PRK12527  79 --ERLHSPSPQTR-----LDLGQRLAL---LQRALAELPPACRDSFLLRKLEGLSHQQIAEHLGISRSLVEKHIVNAMKH 148

                 ....*.
gi 489327667 180 LRKQLR 185
Cdd:PRK12527 149 CRVRMR 154
PRK07037 PRK07037
extracytoplasmic-function sigma-70 factor; Validated
37-181 1.87e-08

extracytoplasmic-function sigma-70 factor; Validated


Pssm-ID: 180803 [Multi-domain]  Cd Length: 163  Bit Score: 51.22  E-value: 1.87e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  37 RMLGNVHEAEDIAQEAFIRAYVNIDSFDINRKFStWLYRIATNLTIDRIRKK--KPDYYLDAEvagtEGLTMYSQivadG 114
Cdd:PRK07037  17 RIVGCRSRAEDVVQDAFVKLVEAPNQDAVKQPVA-YLFRIVRNLAIDHYRRQalENKYHGDEE----DGLDVPSP----E 87
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489327667 115 VLPEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKTRIhrgREALR 181
Cdd:PRK07037  88 ASPEAALINRDTLRHVADALSELPARTRYAFEMYRLHGETQKDIARELGVSPTLVNFMI---RDALV 151
PRK12542 PRK12542
RNA polymerase sigma factor; Provisional
11-181 2.66e-08

RNA polymerase sigma factor; Provisional


Pssm-ID: 183581 [Multi-domain]  Cd Length: 185  Bit Score: 51.21  E-value: 2.66e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  11 QVKKGDQDAFADIVDIYKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNIDS-FDIN-RKFSTWLYRIATNLTIDRIRKK 88
Cdd:PRK12542   2 KVTNNDYEKMEELYELYEQKVYYVAYSILNNIQQAEDAVQETFITLYKNLEKlHSLNtQELKRYILRVAKNKAIDSYRKN 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  89 K------PDYYLDAEVAGTEGLTMYSQIVADGVLPEDAVVSLELSNtiqqkilklpdkyRTVIVLKYIDELSLIEIGEIL 162
Cdd:PRK12542  82 KrhetflEEYERESIEAVDENIEEWEKRKMSEVQIDTLLKELNESN-------------RQVFKYKVFYNLTYQEISSVM 148
                        170
                 ....*....|....*....
gi 489327667 163 NIPVGTVKTRIHRGREALR 181
Cdd:PRK12542 149 GITEANVRKQFERARKRVQ 167
PRK12512 PRK12512
RNA polymerase sigma factor; Provisional
42-186 2.75e-08

RNA polymerase sigma factor; Provisional


Pssm-ID: 171551 [Multi-domain]  Cd Length: 184  Bit Score: 51.24  E-value: 2.75e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  42 VHEAEDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATNLTIDRIRKKkpdyyldaevagteGLTMYSQI--VADGVLPED 119
Cdd:PRK12512  50 ADQAEDIVQEILLAVHLKRHTWDPGAPFAPWLFAIARNKLIDALRRR--------------GRRVFVDIddFAETLPAEP 115
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489327667 120 AVVSLELSNtIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKTRIHRGREALRKQLRD 186
Cdd:PRK12512 116 ATETLPAGD-VGRHLETLPPRQRDVVQSISVEGASIKETAAKLSMSEGAVRVALHRGLAALAAKFRS 181
sigI PRK09635
RNA polymerase sigma factor SigI; Provisional
34-177 2.81e-08

RNA polymerase sigma factor SigI; Provisional


Pssm-ID: 182008 [Multi-domain]  Cd Length: 290  Bit Score: 52.28  E-value: 2.81e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  34 LCYRMLGNVHEAEDIAQEAFIR-AYVNIDSFDINRkfsTWLYRIATNLTIDRIRKKKpdyyLDAEVAGTEGLTMYSQIVA 112
Cdd:PRK09635  21 LAFRMVGDIGVAEDMVQEAFSRlLRAPVGDIDDER---GWLIVVTSRLCLDHIKSAS----TRRERPQDIAAWHDGDASV 93
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489327667 113 DGVLPEDAV-VSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKTRIHRGR 177
Cdd:PRK09635  94 SSVDPADRVtLDDEVRLALLIMLERLGPAERVVFVLHEIFGLPYQQIATTIGSQASTCRQLAHRAR 159
Sigma70_ECF pfam07638
ECF sigma factor; These proteins are probably RNA polymerase sigma factors belonging to the ...
9-186 4.19e-08

ECF sigma factor; These proteins are probably RNA polymerase sigma factors belonging to the extra-cytoplasmic function (ECF) subfamily and show sequence similarity to pfam04542 and pfam04545.


Pssm-ID: 254323 [Multi-domain]  Cd Length: 185  Bit Score: 50.49  E-value: 4.19e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667    9 IKQVKKGDQDAFADIVDIYKDKIYQLCYRMLGN---VHEAEDIA--QEAFIRAYVNIDSFDINRKfsTWLYRIATNLT-- 81
Cdd:pfam07638   8 LQQVKDGDAAATEQLLPLVYDELRRLAGSKLQNerrGHTLQPTAlvHEAFVRLVDTEDFPDWSGR--GHFFAAAAEAMrr 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667   82 --IDRIRKKKPDyyldaEVAGTEGLTMYSQIVADGVLPEDAVVsLELSNTIQQkILKLPDKYRTVIVLKYIDELSLIEIG 159
Cdd:pfam07638  86 ilIDHARRRQRQ-----KRGGDVQRRELDEVVDNGDSPNPDLL-LDLDEALEQ-LFSLSPRQARLVELRFFAGLSNDEIA 158
                         170       180
                  ....*....|....*....|....*..
gi 489327667  160 EILNIPVGTVKTRIHRGREALRKQLRD 186
Cdd:pfam07638 159 ERLGVSERTVERNWALARAWLHRELRD 185
PRK12525 PRK12525
RNA polymerase sigma factor; Provisional
37-175 6.58e-08

RNA polymerase sigma factor; Provisional


Pssm-ID: 139037 [Multi-domain]  Cd Length: 168  Bit Score: 49.94  E-value: 6.58e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  37 RMLGNVHEAEDIAQEAFIRAYVNIDSFDInRKFSTWLYRIATNLTIDRIRKKkpdyylDAEVAGTEGLTMYSQIVADGvl 116
Cdd:PRK12525  28 RQLGCPHSAEDIASETFLQVLALPDPASI-REPRALLTTIARRLMYEGWRRQ------DLERAYLQSLAEAPEAVQPS-- 98
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 489327667 117 PEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGtvktRIHR 175
Cdd:PRK12525  99 PEEQWMVIETLLAIDRLLDGLSGKARAAFLMSQLEGLTYVEIGERLGVSLS----RIHQ 153
PRK09047 PRK09047
RNA polymerase factor sigma-70; Validated
39-187 1.26e-07

RNA polymerase factor sigma-70; Validated


Pssm-ID: 236367 [Multi-domain]  Cd Length: 161  Bit Score: 48.81  E-value: 1.26e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  39 LGNVHEAEDIAQEAFIRayvnidsfdINRKFST-----W---LYRIATNLTIDRIRKKK---------PDYYLDAEVAGT 101
Cdd:PRK09047   1 VRDDDAALDIVQDAMIK---------LAEKYGDrpaaeWpplFQRILQNRIHDWFRRQKvrntwvslfSSFSDDDDDDDF 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667 102 EGLTMYSQIVADGVLPEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKTRIHRGREALR 181
Cdd:PRK09047  72 DPLETLDSADEGAESPADKLERAQVLQLIEEAIQKLPARQREAFLLRYWEDMDVAETAAAMGCSEGSVKTHCSRATHALA 151

                 ....*.
gi 489327667 182 KQLRDL 187
Cdd:PRK09047 152 KALEAK 157
PRK12530 PRK12530
RNA polymerase sigma factor; Provisional
45-89 3.83e-07

RNA polymerase sigma factor; Provisional


Pssm-ID: 237128 [Multi-domain]  Cd Length: 189  Bit Score: 48.22  E-value: 3.83e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 489327667  45 AEDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATNLTIDRIRKKK 89
Cdd:PRK12530  34 AEDVVQEALVSAYKNADSFKGQSALKTWIFAILKNKIIDLIRYRK 78
PRK07670 PRK07670
FliA/WhiG family RNA polymerase sigma factor;
102-164 1.16e-06

FliA/WhiG family RNA polymerase sigma factor;


Pssm-ID: 181075 [Multi-domain]  Cd Length: 251  Bit Score: 47.35  E-value: 1.16e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489327667 102 EGLTMYSQIVAD-GVLPEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNI 164
Cdd:PRK07670 166 DGENVSVTIRDDkTPTPEEKLLKEELIEELAEKIKQLSEKEQLVISLFYKEELTLTEIGQVLNL 229
PRK12535 PRK12535
RNA polymerase sigma factor; Provisional
14-180 1.18e-06

RNA polymerase sigma factor; Provisional


Pssm-ID: 237130 [Multi-domain]  Cd Length: 196  Bit Score: 46.81  E-value: 1.18e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  14 KGDQDAFADIVDIYKDKIYQLCYRmLGNVHEAEDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATNLTIDRIR------- 86
Cdd:PRK12535  21 RGDRAALTEFIRETQDDVWRLLAH-LGGHDIADDLTQETYLRVMSALPRFAARSSARTWLLSLARRVWVDNIRhdmarpr 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  87 KKKPDYY-LDAEVAGTEGLTMYSQIVadgvlpedavvslelsnTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIP 165
Cdd:PRK12535 100 KSATEYEdAAATTASNETTGSWSEWI-----------------DVRTLIDALPPERREALILTQVLGYTYEEAAKIADVR 162
                        170
                 ....*....|....*
gi 489327667 166 VGTVKTRIHRGREAL 180
Cdd:PRK12535 163 VGTIRSRVARARADL 177
PRK08295 PRK08295
RNA polymerase sporulation sigma factor SigH;
9-186 1.56e-06

RNA polymerase sporulation sigma factor SigH;


Pssm-ID: 181361 [Multi-domain]  Cd Length: 208  Bit Score: 46.44  E-value: 1.56e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667   9 IKQVKKGDQDAFADIVDIYKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNIDSFDINR--KFSTWLYRIATNLTIDRI- 85
Cdd:PRK08295  15 VELARSGDKEALEYLIEKYKNFVRAKARSYFLIGADREDIVQEGMIGLYKAIRDYDKDKlsSFKSFAELCITRQIITAIk 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  86 ---RKK-----------KPDYylDAEVAGTEGLTMYSQIVADgvlPEDAVVSLELSNTIQQKILK-LPDKYRTVIVLkYI 150
Cdd:PRK08295  95 tanRQKhiplnsyvsldKPIY--DEESDRTLLDVISEAKVTD---PEELIISKEELEDIEEKIEElLSELEKEVLEL-YL 168
                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 489327667 151 DELSLIEIGEILNIPVGTVKTRIHRGREALRKQLRD 186
Cdd:PRK08295 169 DGKSYQEIAEELNRHVKSIDNALQRVKRKLEKYLEN 204
COG4941 COG4941
Predicted RNA polymerase sigma factor, contains C-terminal TPR domain [Transcription];
37-87 3.51e-05

Predicted RNA polymerase sigma factor, contains C-terminal TPR domain [Transcription];


Pssm-ID: 443968 [Multi-domain]  Cd Length: 412  Bit Score: 43.16  E-value: 3.51e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 489327667  37 RMLGNVHEAEDIAQEAFIRAYVN--IDSfdINRKFSTWLYRIATNLTIDRIRK 87
Cdd:COG4941   25 RRFGDLDLAEDAVQDAFLAALEQwpRDG--VPDNPAAWLYTVARRRAIDRLRR 75
PRK09651 PRK09651
RNA polymerase sigma factor FecI; Provisional
37-178 3.94e-05

RNA polymerase sigma factor FecI; Provisional


Pssm-ID: 182018 [Multi-domain]  Cd Length: 172  Bit Score: 42.10  E-value: 3.94e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  37 RMLGNVHEAEDIAQEAFIRAYVNiDSFDINRKFSTWLYRIATNLTIDRIRKKKpdyyldAEVAGTEGLTMYSQIVADGvl 116
Cdd:PRK09651  29 RKLQSAFDADDIAQDTFLRVMVS-ETLSTIRDPRSFLCTIAKRVMVDLFRRNA------LEKAYLEMLALMPEGGAPS-- 99
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489327667 117 PEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKTRIHRGRE 178
Cdd:PRK09651 100 PEERESQLETLQLLDSMLDGLNGKTREAFLLSQLDGLTYSEIAHKLGVSVSSVKKYVAKATE 161
PRK06704 PRK06704
RNA polymerase subunit sigma-70;
35-181 7.45e-05

RNA polymerase subunit sigma-70;


Pssm-ID: 180663 [Multi-domain]  Cd Length: 228  Bit Score: 41.93  E-value: 7.45e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  35 CYRMLGNVHEAEDIAQEAFIRAYVNIDSFDInrkFSTWLYRIATNLTIDRIRKKKPDYYLDAEVAGTEGltmySQIVADg 114
Cdd:PRK06704  34 CTFLTKNKWDGEDLAQETVCKVLQKYSNKDI---CMTLVYKIARNRWLDQIKSKSVHEKIRDQITFEEP----HEKIAD- 105
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489327667 115 vLPEDAVVSLELSNTIQQKILKLPDkyrtviVLKYidelSLIEIGEILNIPVGTVKTRIHRGREALR 181
Cdd:PRK06704 106 -LHEMVGKVLSSLNVQQSAILLLKD------VFQY----SIADIAKVCSVSEGAVKASLFRSRNRLK 161
PRK12536 PRK12536
RNA polymerase sigma factor; Provisional
44-186 8.39e-05

RNA polymerase sigma factor; Provisional


Pssm-ID: 237131 [Multi-domain]  Cd Length: 181  Bit Score: 41.19  E-value: 8.39e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  44 EAEDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATNLTIDRIRKKKpdyyldAEVAGTEGLTMYSQIVADgvlPED--AV 121
Cdd:PRK12536  48 EVEDLVQEILLAVHNARHTYRADQPLTAWVHAIARYKLMDFLRSRA------RREALHDPLDDESELFAT---SDDeaAE 118
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489327667 122 VSLELSNTIQQkilkLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKTRIHRGREALRKQLRD 186
Cdd:PRK12536 119 ARRDLGKLLEQ----LPDRQRLPIVHVKLEGLSVAETAQLTGLSESAVKVGIHRGLKALAAKIRG 179
PRK06288 PRK06288
RNA polymerase sigma factor WhiG; Reviewed
117-164 1.17e-04

RNA polymerase sigma factor WhiG; Reviewed


Pssm-ID: 235770 [Multi-domain]  Cd Length: 268  Bit Score: 41.60  E-value: 1.17e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 489327667 117 PEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNI 164
Cdd:PRK06288 193 PDEIAEREEIKRVIVEAIKTLPEREKKVLILYYYEDLTLKEIGKVLGV 240
PRK12529 PRK12529
RNA polymerase sigma factor; Provisional
34-176 2.04e-04

RNA polymerase sigma factor; Provisional


Pssm-ID: 183574 [Multi-domain]  Cd Length: 178  Bit Score: 40.30  E-value: 2.04e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  34 LCYRMLGNVHE-AEDIAQEAFIRAYVN--IDSFDINRKFSTWLYRIATNLTIDRIRKKKpdyyldAEVAGTEGLTMYSQI 110
Cdd:PRK12529  30 LAYRLRSWGRGvADDLAHDIFLRILASrdGGQREAIRQPRAYLARIANCVLVSWRRRQS------LELAWLEALATLPEP 103
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489327667 111 VADGvlPEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKTRIHRG 176
Cdd:PRK12529 104 LHPS--PEQQSVILETLHEIDALLDTLRPRVKQAFLMATLDGMKQKDIAQALDIALPTVKKYIHQA 167
fliA PRK06986
flagellar biosynthesis sigma factor; Validated
117-164 3.74e-04

flagellar biosynthesis sigma factor; Validated


Pssm-ID: 235901 [Multi-domain]  Cd Length: 236  Bit Score: 39.83  E-value: 3.74e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 489327667 117 PEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNI 164
Cdd:PRK06986 165 PLQQLEDEELREALVEAIESLPEREQLVLSLYYQEELNLKEIGAVLGV 212
HTH_16 pfam12645
Helix-turn-helix domain; This domain appears to be a helix-turn-helix domain suggesting that ...
9-64 1.03e-03

Helix-turn-helix domain; This domain appears to be a helix-turn-helix domain suggesting that this might be a transcriptional regulatory protein. Some members of this family are annotated as conjugative transposon domains.


Pssm-ID: 463654  Cd Length: 65  Bit Score: 36.05  E-value: 1.03e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489327667    9 IKQVKKGDQDAFADIVDIYKDKIYQLCYRML----GNVHE--AEDIAQEAFIRAYVNIDSFD 64
Cdd:pfam12645   4 IEKAVNGDEEAIEEILKHYEPYIRKLSLRTLydedGNVNGyvDEDLKQELEIKLIEAILKFD 65
PRK05911 PRK05911
RNA polymerase sigma factor sigma-28; Reviewed
119-174 1.59e-03

RNA polymerase sigma factor sigma-28; Reviewed


Pssm-ID: 235644 [Multi-domain]  Cd Length: 257  Bit Score: 38.06  E-value: 1.59e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 489327667 119 DAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVkTRIH 174
Cdd:PRK05911 188 DVVDKKEFSSILAEAILALEEKERKVMALYYYEELVLKEIGKILGVSESRV-SQIH 242
PRK12523 PRK12523
RNA polymerase sigma factor; Reviewed
17-176 2.13e-03

RNA polymerase sigma factor; Reviewed


Pssm-ID: 183572 [Multi-domain]  Cd Length: 172  Bit Score: 37.14  E-value: 2.13e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  17 QDAFADIVD-IYKDK---IYQLCYRMLGNVHEAEDIAQEAFIRaYVNIDSFDINRKFSTWLYRIATNLTIDRIRKKKpdy 92
Cdd:PRK12523   5 QSPHSELVGaLYRDHrgwLLAWLRRNVACRQRAEDLSQDTFVR-LLGRPELPTPREPRAFLAAVAKGLMFDHFRRAA--- 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  93 yldAEVAGTEGLTMYSQivADGVLPEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKTR 172
Cdd:PRK12523  81 ---LEQAYLAELALVPE--AEQPSPEEQHLILEDLKAIDRLLGKLSSKARAAFLYNRLDGMGHAEIAERLGVSVSRVRQY 155

                 ....
gi 489327667 173 IHRG 176
Cdd:PRK12523 156 LAQG 159
PRK12528 PRK12528
RNA polymerase sigma factor; Provisional
37-181 2.56e-03

RNA polymerase sigma factor; Provisional


Pssm-ID: 171561 [Multi-domain]  Cd Length: 161  Bit Score: 36.75  E-value: 2.56e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  37 RMLGNVHEAEDIAQEAFIRAYVNIDSFDIN--RKFstwLYRIATNLTIDRIRKKkpdyylDAEVAGTEGLTMYSQIVADG 114
Cdd:PRK12528  23 RRLGCPQSAADLAQDTFVKVLVARETAQIIepRAF---LTTIAKRVLCNHYRRQ------DLERAYLEALAQLPERVAPS 93
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489327667 115 vlPEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYIDELSLIEIGEILNIPVGTVKTriHRGREALR 181
Cdd:PRK12528  94 --EEERAIILETLVELDQLLDGLPPLVKRAFLLAQVDGLGYGEIATELGISLATVKR--YLNKAAMR 156
RpoD COG0568
DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) [Transcription]; DNA-directed RNA ...
77-164 6.33e-03

DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) [Transcription]; DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 440334 [Multi-domain]  Cd Length: 268  Bit Score: 36.18  E-value: 6.33e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489327667  77 ATNLTIDRIRK----KKPDYYLDAEVAGTEGLTMYSQIVADG-VLPEDAVVSLELSNTIQQKILKLPDKYRTVIVLKYI- 150
Cdd:COG0568  142 ELGVPEEKVREmlrlAREPVSLDAPVGDDEDSELGDLLEDEEaPSPEEALEEELLREELREALDTLTEREREILRLRFGl 221
                         90
                 ....*....|....*..
gi 489327667 151 ---DELSLIEIGEILNI 164
Cdd:COG0568  222 ddgEPHTLEEIGKEFGV 238
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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