|
Name |
Accession |
Description |
Interval |
E-value |
| Eno |
COG0148 |
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: ... |
1-428 |
0e+00 |
|
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439918 [Multi-domain] Cd Length: 426 Bit Score: 943.68 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 1 MPYIVDVYAREVLDSRGNPTVEVEVYTETGAFGRALVPSGASTGEYEAVELRDGDKDRYLGKGVLTAVNNVNEIIAPELL 80
Cdd:COG0148 1 MSRIEDVHAREILDSRGNPTVEVEVTLEDGAVGRAAVPSGASTGSHEAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 81 GFDVTEQNAIDQLLIELDGTENKGKLGANAILGVSMACARAAADFLQIPLYQYLGGFNSKTLPVPMMNIVNGGEHADNNV 160
Cdd:COG0148 81 GMDATDQRAIDRAMIELDGTPNKSRLGANAILGVSLAVAKAAAAALGLPLYRYLGGVNAKTLPVPMMNIINGGAHADNNV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 161 DIQEFMIMPVGAPNFREALRMGAQIFHSLKSVLSAKGLNTAVGDEGGFAPNLGSNEEALQTIVEAIEKAGFKPGEEVKLA 240
Cdd:COG0148 161 DIQEFMIMPVGAPSFSEALRMGAEVFHALKKVLKEKGLSTAVGDEGGFAPNLKSNEEALELILEAIEKAGYKPGEDIALA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 241 MDAASSEFYnkEDGKYHLSGEGVVKTSAEMVDWYEELVSKYPIISIEDGLDENDWEGHKLLTERLGKKVQLVGDDLFVTN 320
Cdd:COG0148 241 LDVAASEFY--KDGKYHLKGEGKELTSEEMIDYYADLVDKYPIVSIEDGLAEDDWDGWKLLTEKLGDKVQLVGDDLFVTN 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 321 TKKLSEGIKNGVGNSILIKVNQIGTLTETFDAIEMAKRAGYTAVISHRSGETEDSTIADIAVATNAGQIKTGAPSRTDRV 400
Cdd:COG0148 319 PKRLKKGIEEGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSPSRSERV 398
|
410 420
....*....|....*....|....*...
gi 489321005 401 AKYNQLLRIEDQLAETAQYHGINSFYNL 428
Cdd:COG0148 399 AKYNQLLRIEEELGDAARYAGRSAFKRL 426
|
|
| eno |
PRK00077 |
enolase; Provisional |
1-429 |
0e+00 |
|
enolase; Provisional
Pssm-ID: 234617 [Multi-domain] Cd Length: 425 Bit Score: 911.78 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 1 MPYIVDVYAREVLDSRGNPTVEVEVYTETGAFGRALVPSGASTGEYEAVELRDGDKDRYLGKGVLTAVNNVNEIIAPELL 80
Cdd:PRK00077 1 MSKIEDIIAREILDSRGNPTVEVEVTLEDGAFGRAAVPSGASTGEREAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 81 GFDVTEQNAIDQLLIELDGTENKGKLGANAILGVSMACARAAADFLQIPLYQYLGGFNSKTLPVPMMNIVNGGEHADNNV 160
Cdd:PRK00077 81 GLDALDQRAIDKAMIELDGTPNKSKLGANAILGVSLAVAKAAADSLGLPLYRYLGGPNAKVLPVPMMNIINGGAHADNNV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 161 DIQEFMIMPVGAPNFREALRMGAQIFHSLKSVLSAKGLNTAVGDEGGFAPNLGSNEEALQTIVEAIEKAGFKPGEEVKLA 240
Cdd:PRK00077 161 DIQEFMIMPVGAPSFKEALRMGAEVFHTLKKVLKEKGLSTAVGDEGGFAPNLKSNEEALDLILEAIEKAGYKPGEDIALA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 241 MDAASSEFYnkEDGKYHLSGEGvvKTSAEMVDWYEELVSKYPIISIEDGLDENDWEGHKLLTERLGKKVQLVGDDLFVTN 320
Cdd:PRK00077 241 LDCAASEFY--KDGKYVLEGEG--LTSEEMIDYLAELVDKYPIVSIEDGLDENDWEGWKLLTEKLGDKVQLVGDDLFVTN 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 321 TKKLSEGIKNGVGNSILIKVNQIGTLTETFDAIEMAKRAGYTAVISHRSGETEDSTIADIAVATNAGQIKTGAPSRTDRV 400
Cdd:PRK00077 317 TKRLKKGIEKGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVVSHRSGETEDTTIADLAVATNAGQIKTGSLSRSERI 396
|
410 420
....*....|....*....|....*....
gi 489321005 401 AKYNQLLRIEDQLAETAQYHGINSFYNLN 429
Cdd:PRK00077 397 AKYNQLLRIEEELGDAARYAGKKAFKNLK 425
|
|
| eno |
TIGR01060 |
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis ... |
4-428 |
0e+00 |
|
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 213580 [Multi-domain] Cd Length: 425 Bit Score: 823.53 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 4 IVDVYAREVLDSRGNPTVEVEVYTETGAFGRALVPSGASTGEYEAVELRDGDKDRYLGKGVLTAVNNVNEIIAPELLGFD 83
Cdd:TIGR01060 1 IVDIRAREILDSRGNPTVEVEVILEDGTFGRAAVPSGASTGEREALELRDGDKKRYLGKGVLKAVENVNEIIAPELIGMD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 84 VTEQNAIDQLLIELDGTENKGKLGANAILGVSMACARAAADFLQIPLYQYLGGFNSKTLPVPMMNIVNGGEHADNNVDIQ 163
Cdd:TIGR01060 81 ATDQREIDQILIELDGTPNKSKLGANAILGVSMAVAKAAADSLGLPLYRYLGGFNAYVLPVPMMNIINGGAHADNNLDFQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 164 EFMIMPVGAPNFREALRMGAQIFHSLKSVLSAKGLNTAVGDEGGFAPNLGSNEEALQTIVEAIEKAGFKPGEEVKLAMDA 243
Cdd:TIGR01060 161 EFMIMPVGAPSFREALRMGAEVFHALKKLLKEKGLATGVGDEGGFAPNLASNEEALEIIVEAIEKAGYKPGEDVALALDC 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 244 ASSEFYNKEDGKYHLSGEGVVKTSAEMVDWYEELVSKYPIISIEDGLDENDWEGHKLLTERLGKKVQLVGDDLFVTNTKK 323
Cdd:TIGR01060 241 AASEFYDEEDGKYVYKGENKQLTSEEMIEYYEELVEKYPIISIEDGLSEEDWEGWAELTKRLGDKVQIVGDDLFVTNTEI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 324 LSEGIKNGVGNSILIKVNQIGTLTETFDAIEMAKRAGYTAVISHRSGETEDSTIADIAVATNAGQIKTGAPSRTDRVAKY 403
Cdd:TIGR01060 321 LREGIEMGVANSILIKPNQIGTLTETLDAIELAKKAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSLSRSERIAKY 400
|
410 420
....*....|....*....|....*
gi 489321005 404 NQLLRIEDQLAETAQYHGINSFYNL 428
Cdd:TIGR01060 401 NQLLRIEEELGDSARYAGKNSFYRF 425
|
|
| enolase |
cd03313 |
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of ... |
6-412 |
0e+00 |
|
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions.
Pssm-ID: 239429 [Multi-domain] Cd Length: 408 Bit Score: 785.52 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 6 DVYAREVLDSRGNPTVEVEVYTETGAFGRALVPSGASTGEYEAVELRDGDKDRYLGKGVLTAVNNVNEIIAPELLGFDVT 85
Cdd:cd03313 1 KIKAREILDSRGNPTVEVEVTTEDGGVGRAAVPSGASTGEHEAVELRDGDKSRYLGKGVLKAVKNVNEIIAPALIGMDVT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 86 EQNAIDQLLIELDGTENKGKLGANAILGVSMACARAAADFLQIPLYQYLGGFNSKTLPVPMMNIVNGGEHADNNVDIQEF 165
Cdd:cd03313 81 DQRAIDKLLIELDGTPNKSKLGANAILGVSLAVAKAAAAALGLPLYRYLGGLAAYVLPVPMFNVINGGAHAGNKLDFQEF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 166 MIMPVGAPNFREALRMGAQIFHSLKSVLSAKG--LNTAVGDEGGFAPNLGSNEEALQTIVEAIEKAGFKPGEEVKLAMDA 243
Cdd:cd03313 161 MIVPVGAPSFSEALRMGAEVYHTLKKVLKKKGglLATNVGDEGGFAPNLSSNEEALDLLVEAIEKAGYEPGKKIAIALDV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 244 ASSEFYNKEDGKYHlSGEGVVKTSAEMVDWYEELVSKYPIISIEDGLDENDWEGHKLLTERLGKKVQLVGDDLFVTNTKK 323
Cdd:cd03313 241 AASEFYDEGKYVYD-SDEGKKLTSEELIDYYKELVKKYPIVSIEDPFDEDDWEGWAKLTAKLGDKIQIVGDDLFVTNPER 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 324 LSEGIKNGVGNSILIKVNQIGTLTETFDAIEMAKRAGYTAVISHRSGETEDSTIADIAVATNAGQIKTGAPSRTDRVAKY 403
Cdd:cd03313 320 LKKGIEKKAANALLIKVNQIGTLTETIEAIKLAKKNGYGVVVSHRSGETEDTFIADLAVALGAGQIKTGAPCRSERTAKY 399
|
....*....
gi 489321005 404 NQLLRIEDQ 412
Cdd:cd03313 400 NQLLRIEEE 408
|
|
| Enolase_C |
pfam00113 |
Enolase, C-terminal TIM barrel domain; |
139-428 |
0e+00 |
|
Enolase, C-terminal TIM barrel domain;
Pssm-ID: 395063 Cd Length: 296 Bit Score: 509.71 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 139 SKTLPVPMMNIVNGGEHADNNVDIQEFMIMPVGAPNFREALRMGAQIFHSLKSVLSAKG--LNTAVGDEGGFAPNLGSNE 216
Cdd:pfam00113 1 SYVLPVPMMNVINGGSHAGNNLAFQEFMILPTGAPSFSEAMRMGAEVYHHLKSVLKAKYgqSATNVGDEGGFAPNLQSNK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 217 EALQTIVEAIEKAGFKPgeEVKLAMDAASSEFYNKEDGKYHLSGEG------VVKTSAEMVDWYEELVSKYPIISIEDGL 290
Cdd:pfam00113 81 EALDLIVEAIEKAGYKG--KIKIAMDVASSEFYNKKDGKYDLDFKGeksdksKKLTSAQLADLYEELVKKYPIVSIEDPF 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 291 DENDWEGHKLLTERLGKKVQLVGDDLFVTNTKKLSEGIKNGVGNSILIKVNQIGTLTETFDAIEMAKRAGYTAVISHRSG 370
Cdd:pfam00113 159 DEDDWEAWKYLTERLGDKVQIVGDDLTVTNPKRLKTAIEKKIANALLLKVNQIGSLTESIAAVKMAKDAGWGVMVSHRSG 238
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 489321005 371 ETEDSTIADIAVATNAGQIKTGAPSRTDRVAKYNQLLRIEDQLAETAQYHGINSFYNL 428
Cdd:pfam00113 239 ETEDTTIADLAVGLNAGQIKTGAPCRSERLAKYNQLLRIEEELGSEAKYAGRSFRKPL 296
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Eno |
COG0148 |
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: ... |
1-428 |
0e+00 |
|
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439918 [Multi-domain] Cd Length: 426 Bit Score: 943.68 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 1 MPYIVDVYAREVLDSRGNPTVEVEVYTETGAFGRALVPSGASTGEYEAVELRDGDKDRYLGKGVLTAVNNVNEIIAPELL 80
Cdd:COG0148 1 MSRIEDVHAREILDSRGNPTVEVEVTLEDGAVGRAAVPSGASTGSHEAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 81 GFDVTEQNAIDQLLIELDGTENKGKLGANAILGVSMACARAAADFLQIPLYQYLGGFNSKTLPVPMMNIVNGGEHADNNV 160
Cdd:COG0148 81 GMDATDQRAIDRAMIELDGTPNKSRLGANAILGVSLAVAKAAAAALGLPLYRYLGGVNAKTLPVPMMNIINGGAHADNNV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 161 DIQEFMIMPVGAPNFREALRMGAQIFHSLKSVLSAKGLNTAVGDEGGFAPNLGSNEEALQTIVEAIEKAGFKPGEEVKLA 240
Cdd:COG0148 161 DIQEFMIMPVGAPSFSEALRMGAEVFHALKKVLKEKGLSTAVGDEGGFAPNLKSNEEALELILEAIEKAGYKPGEDIALA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 241 MDAASSEFYnkEDGKYHLSGEGVVKTSAEMVDWYEELVSKYPIISIEDGLDENDWEGHKLLTERLGKKVQLVGDDLFVTN 320
Cdd:COG0148 241 LDVAASEFY--KDGKYHLKGEGKELTSEEMIDYYADLVDKYPIVSIEDGLAEDDWDGWKLLTEKLGDKVQLVGDDLFVTN 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 321 TKKLSEGIKNGVGNSILIKVNQIGTLTETFDAIEMAKRAGYTAVISHRSGETEDSTIADIAVATNAGQIKTGAPSRTDRV 400
Cdd:COG0148 319 PKRLKKGIEEGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSPSRSERV 398
|
410 420
....*....|....*....|....*...
gi 489321005 401 AKYNQLLRIEDQLAETAQYHGINSFYNL 428
Cdd:COG0148 399 AKYNQLLRIEEELGDAARYAGRSAFKRL 426
|
|
| eno |
PRK00077 |
enolase; Provisional |
1-429 |
0e+00 |
|
enolase; Provisional
Pssm-ID: 234617 [Multi-domain] Cd Length: 425 Bit Score: 911.78 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 1 MPYIVDVYAREVLDSRGNPTVEVEVYTETGAFGRALVPSGASTGEYEAVELRDGDKDRYLGKGVLTAVNNVNEIIAPELL 80
Cdd:PRK00077 1 MSKIEDIIAREILDSRGNPTVEVEVTLEDGAFGRAAVPSGASTGEREAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 81 GFDVTEQNAIDQLLIELDGTENKGKLGANAILGVSMACARAAADFLQIPLYQYLGGFNSKTLPVPMMNIVNGGEHADNNV 160
Cdd:PRK00077 81 GLDALDQRAIDKAMIELDGTPNKSKLGANAILGVSLAVAKAAADSLGLPLYRYLGGPNAKVLPVPMMNIINGGAHADNNV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 161 DIQEFMIMPVGAPNFREALRMGAQIFHSLKSVLSAKGLNTAVGDEGGFAPNLGSNEEALQTIVEAIEKAGFKPGEEVKLA 240
Cdd:PRK00077 161 DIQEFMIMPVGAPSFKEALRMGAEVFHTLKKVLKEKGLSTAVGDEGGFAPNLKSNEEALDLILEAIEKAGYKPGEDIALA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 241 MDAASSEFYnkEDGKYHLSGEGvvKTSAEMVDWYEELVSKYPIISIEDGLDENDWEGHKLLTERLGKKVQLVGDDLFVTN 320
Cdd:PRK00077 241 LDCAASEFY--KDGKYVLEGEG--LTSEEMIDYLAELVDKYPIVSIEDGLDENDWEGWKLLTEKLGDKVQLVGDDLFVTN 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 321 TKKLSEGIKNGVGNSILIKVNQIGTLTETFDAIEMAKRAGYTAVISHRSGETEDSTIADIAVATNAGQIKTGAPSRTDRV 400
Cdd:PRK00077 317 TKRLKKGIEKGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVVSHRSGETEDTTIADLAVATNAGQIKTGSLSRSERI 396
|
410 420
....*....|....*....|....*....
gi 489321005 401 AKYNQLLRIEDQLAETAQYHGINSFYNLN 429
Cdd:PRK00077 397 AKYNQLLRIEEELGDAARYAGKKAFKNLK 425
|
|
| eno |
TIGR01060 |
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis ... |
4-428 |
0e+00 |
|
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 213580 [Multi-domain] Cd Length: 425 Bit Score: 823.53 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 4 IVDVYAREVLDSRGNPTVEVEVYTETGAFGRALVPSGASTGEYEAVELRDGDKDRYLGKGVLTAVNNVNEIIAPELLGFD 83
Cdd:TIGR01060 1 IVDIRAREILDSRGNPTVEVEVILEDGTFGRAAVPSGASTGEREALELRDGDKKRYLGKGVLKAVENVNEIIAPELIGMD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 84 VTEQNAIDQLLIELDGTENKGKLGANAILGVSMACARAAADFLQIPLYQYLGGFNSKTLPVPMMNIVNGGEHADNNVDIQ 163
Cdd:TIGR01060 81 ATDQREIDQILIELDGTPNKSKLGANAILGVSMAVAKAAADSLGLPLYRYLGGFNAYVLPVPMMNIINGGAHADNNLDFQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 164 EFMIMPVGAPNFREALRMGAQIFHSLKSVLSAKGLNTAVGDEGGFAPNLGSNEEALQTIVEAIEKAGFKPGEEVKLAMDA 243
Cdd:TIGR01060 161 EFMIMPVGAPSFREALRMGAEVFHALKKLLKEKGLATGVGDEGGFAPNLASNEEALEIIVEAIEKAGYKPGEDVALALDC 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 244 ASSEFYNKEDGKYHLSGEGVVKTSAEMVDWYEELVSKYPIISIEDGLDENDWEGHKLLTERLGKKVQLVGDDLFVTNTKK 323
Cdd:TIGR01060 241 AASEFYDEEDGKYVYKGENKQLTSEEMIEYYEELVEKYPIISIEDGLSEEDWEGWAELTKRLGDKVQIVGDDLFVTNTEI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 324 LSEGIKNGVGNSILIKVNQIGTLTETFDAIEMAKRAGYTAVISHRSGETEDSTIADIAVATNAGQIKTGAPSRTDRVAKY 403
Cdd:TIGR01060 321 LREGIEMGVANSILIKPNQIGTLTETLDAIELAKKAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSLSRSERIAKY 400
|
410 420
....*....|....*....|....*
gi 489321005 404 NQLLRIEDQLAETAQYHGINSFYNL 428
Cdd:TIGR01060 401 NQLLRIEEELGDSARYAGKNSFYRF 425
|
|
| enolase |
cd03313 |
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of ... |
6-412 |
0e+00 |
|
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions.
Pssm-ID: 239429 [Multi-domain] Cd Length: 408 Bit Score: 785.52 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 6 DVYAREVLDSRGNPTVEVEVYTETGAFGRALVPSGASTGEYEAVELRDGDKDRYLGKGVLTAVNNVNEIIAPELLGFDVT 85
Cdd:cd03313 1 KIKAREILDSRGNPTVEVEVTTEDGGVGRAAVPSGASTGEHEAVELRDGDKSRYLGKGVLKAVKNVNEIIAPALIGMDVT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 86 EQNAIDQLLIELDGTENKGKLGANAILGVSMACARAAADFLQIPLYQYLGGFNSKTLPVPMMNIVNGGEHADNNVDIQEF 165
Cdd:cd03313 81 DQRAIDKLLIELDGTPNKSKLGANAILGVSLAVAKAAAAALGLPLYRYLGGLAAYVLPVPMFNVINGGAHAGNKLDFQEF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 166 MIMPVGAPNFREALRMGAQIFHSLKSVLSAKG--LNTAVGDEGGFAPNLGSNEEALQTIVEAIEKAGFKPGEEVKLAMDA 243
Cdd:cd03313 161 MIVPVGAPSFSEALRMGAEVYHTLKKVLKKKGglLATNVGDEGGFAPNLSSNEEALDLLVEAIEKAGYEPGKKIAIALDV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 244 ASSEFYNKEDGKYHlSGEGVVKTSAEMVDWYEELVSKYPIISIEDGLDENDWEGHKLLTERLGKKVQLVGDDLFVTNTKK 323
Cdd:cd03313 241 AASEFYDEGKYVYD-SDEGKKLTSEELIDYYKELVKKYPIVSIEDPFDEDDWEGWAKLTAKLGDKIQIVGDDLFVTNPER 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 324 LSEGIKNGVGNSILIKVNQIGTLTETFDAIEMAKRAGYTAVISHRSGETEDSTIADIAVATNAGQIKTGAPSRTDRVAKY 403
Cdd:cd03313 320 LKKGIEKKAANALLIKVNQIGTLTETIEAIKLAKKNGYGVVVSHRSGETEDTFIADLAVALGAGQIKTGAPCRSERTAKY 399
|
....*....
gi 489321005 404 NQLLRIEDQ 412
Cdd:cd03313 400 NQLLRIEEE 408
|
|
| PTZ00081 |
PTZ00081 |
enolase; Provisional |
1-423 |
0e+00 |
|
enolase; Provisional
Pssm-ID: 240259 [Multi-domain] Cd Length: 439 Bit Score: 621.68 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 1 MPYIVDVYAREVLDSRGNPTVEVEVYTETGAFgRALVPSGASTGEYEAVELRDGDKDRYLGKGVLTAVNNVNEIIAPELL 80
Cdd:PTZ00081 1 MSTIKSIKAREILDSRGNPTVEVDLTTEKGVF-RAAVPSGASTGIYEALELRDGDKSRYLGKGVLKAVENVNEIIAPALI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 81 GFDVTEQNAIDQLLIE-LDGTEN-----KGKLGANAILGVSMACARAAADFLQIPLYQYLGGFNSKT-----LPVPMMNI 149
Cdd:PTZ00081 80 GKDVTDQKKLDKLMVEqLDGTKNewgwcKSKLGANAILAVSMAVARAAAAAKGVPLYKYLAQLAGKPtdkfvLPVPCFNV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 150 VNGGEHADNNVDIQEFMIMPVGAPNFREALRMGAQIFHSLKSVLSAK-GLN-TAVGDEGGFAPNLGSNEEALQTIVEAIE 227
Cdd:PTZ00081 160 INGGKHAGNKLAFQEFMIAPVGAPSFKEALRMGAEVYHSLKSVIKKKyGLDaTNVGDEGGFAPNIKDPEEALDLLVEAIK 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 228 KAGFKpgEEVKLAMDAASSEFYNKEDGKYHL------SGEGVVKTSAEMVDWYEELVSKYPIISIEDGLDENDWEGHKLL 301
Cdd:PTZ00081 240 KAGYE--GKVKICMDVAASEFYDKEKKVYDLdfknpnNDKSNKLTGEELVELYLDLVKKYPIVSIEDPFDQDDWEAYAKL 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 302 TERLGKKVQLVGDDLFVTNTKKLSEGIKNGVGNSILIKVNQIGTLTETFDAIEMAKRAGYTAVISHRSGETEDSTIADIA 381
Cdd:PTZ00081 318 TAAIGQKVQIVGDDLLVTNPTRIKKAIEKKACNALLLKVNQIGTVTEAIEAAKLAQKNGWGVMVSHRSGETEDTFIADLV 397
|
410 420 430 440
....*....|....*....|....*....|....*....|..
gi 489321005 382 VATNAGQIKTGAPSRTDRVAKYNQLLRIEDQLAETAQYHGIN 423
Cdd:PTZ00081 398 VGLGTGQIKTGAPCRSERLAKYNQLLRIEEELGSNAVYAGEN 439
|
|
| PLN00191 |
PLN00191 |
enolase |
1-423 |
0e+00 |
|
enolase
Pssm-ID: 215095 [Multi-domain] Cd Length: 457 Bit Score: 568.96 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 1 MPYIVDVYAREVLDSRGNPTVEVEVYTETGAFgRALVPSGASTGEYEAVELRDGDKDrYLGKGVLTAVNNVNEIIAPELL 80
Cdd:PLN00191 25 MATITKVKARQIIDSRGNPTVEVDLHTSKGMF-RAAVPSGASTGIYEALELRDGDKD-YLGKGVLKAVKNVNEIIAPALI 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 81 GFDVTEQNAIDQLLIELDGTENKGKLGANAILGVSMACARAAADFLQIPLYQY---LGGFNSKTLPVPMMNIVNGGEHAD 157
Cdd:PLN00191 103 GMDPTDQTQIDNFMLELDGTPNKGKLGANAILAVSLAVCKAGAAEKGVPLYKHiadLAGNKKLVLPVPAFNVINGGSHAG 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 158 NNVDIQEFMIMPVGAPNFREALRMGAQIFHSLKSVLSAK--GLNTAVGDEGGFAPNLGSNEEALQTIVEAIEKAGFKpgE 235
Cdd:PLN00191 183 NKLAMQEFMILPVGASSFKEAMQMGSEVYHHLKAVIKKKygQDACNVGDEGGFAPNIQDNKEGLELLKEAIEKAGYT--G 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 236 EVKLAMDAASSEFYNKeDGKYHL------SGEGVVKTSAEMVDWYEELVSKYPIISIEDGLDENDWEGHKLLTERlgKKV 309
Cdd:PLN00191 261 KIKIGMDVAASEFYTK-DKKYDLdfkeenNDGSNKKSGDELIDLYKEFVSDYPIVSIEDPFDQDDWEHWAKLTSL--EDV 337
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 310 QLVGDDLFVTNTKKLSEGIKNGVGNSILIKVNQIGTLTETFDAIEMAKRAGYTAVISHRSGETEDSTIADIAVATNAGQI 389
Cdd:PLN00191 338 QIVGDDLLVTNPKRVAKAIQEKACNALLLKVNQIGTVTESIEAVKMSKAAGWGVMTSHRSGETEDSFIADLAVGLATGQI 417
|
410 420 430
....*....|....*....|....*....|....
gi 489321005 390 KTGAPSRTDRVAKYNQLLRIEDQLAETAQYHGIN 423
Cdd:PLN00191 418 KTGAPCRSERLAKYNQLLRIEEELGDEAVYAGEN 451
|
|
| Enolase_C |
pfam00113 |
Enolase, C-terminal TIM barrel domain; |
139-428 |
0e+00 |
|
Enolase, C-terminal TIM barrel domain;
Pssm-ID: 395063 Cd Length: 296 Bit Score: 509.71 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 139 SKTLPVPMMNIVNGGEHADNNVDIQEFMIMPVGAPNFREALRMGAQIFHSLKSVLSAKG--LNTAVGDEGGFAPNLGSNE 216
Cdd:pfam00113 1 SYVLPVPMMNVINGGSHAGNNLAFQEFMILPTGAPSFSEAMRMGAEVYHHLKSVLKAKYgqSATNVGDEGGFAPNLQSNK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 217 EALQTIVEAIEKAGFKPgeEVKLAMDAASSEFYNKEDGKYHLSGEG------VVKTSAEMVDWYEELVSKYPIISIEDGL 290
Cdd:pfam00113 81 EALDLIVEAIEKAGYKG--KIKIAMDVASSEFYNKKDGKYDLDFKGeksdksKKLTSAQLADLYEELVKKYPIVSIEDPF 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 291 DENDWEGHKLLTERLGKKVQLVGDDLFVTNTKKLSEGIKNGVGNSILIKVNQIGTLTETFDAIEMAKRAGYTAVISHRSG 370
Cdd:pfam00113 159 DEDDWEAWKYLTERLGDKVQIVGDDLTVTNPKRLKTAIEKKIANALLLKVNQIGSLTESIAAVKMAKDAGWGVMVSHRSG 238
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 489321005 371 ETEDSTIADIAVATNAGQIKTGAPSRTDRVAKYNQLLRIEDQLAETAQYHGINSFYNL 428
Cdd:pfam00113 239 ETEDTTIADLAVGLNAGQIKTGAPCRSERLAKYNQLLRIEEELGSEAKYAGRSFRKPL 296
|
|
| Enolase_N |
pfam03952 |
Enolase, N-terminal domain; |
4-134 |
3.57e-93 |
|
Enolase, N-terminal domain;
Pssm-ID: 461105 [Multi-domain] Cd Length: 131 Bit Score: 276.56 E-value: 3.57e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 4 IVDVYAREVLDSRGNPTVEVEVYTETGAFGRALVPSGASTGEYEAVELRDGDKDRYLGKGVLTAVNNVNEIIAPELLGFD 83
Cdd:pfam03952 1 ITKVKAREILDSRGNPTVEVEVTLEDGTFGRAAVPSGASTGEHEAVELRDGDKSRYGGKGVLKAVENVNEIIAPALIGMD 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 489321005 84 VTEQNAIDQLLIELDGTENKGKLGANAILGVSMACARAAADFLQIPLYQYL 134
Cdd:pfam03952 81 ATDQRAIDRALIELDGTENKSKLGANAILGVSLAVAKAAAAALGLPLYRYL 131
|
|
| PRK08350 |
PRK08350 |
hypothetical protein; Provisional |
1-415 |
5.16e-26 |
|
hypothetical protein; Provisional
Pssm-ID: 169397 [Multi-domain] Cd Length: 341 Bit Score: 107.58 E-value: 5.16e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 1 MPYIVDVYAREVLDSRGNPTVEVEVYTETGaFGRALVPSGASTGEYEAVELRdgdkdrylgkgvltAVNNVNEIIAPELL 80
Cdd:PRK08350 1 MTVIENIIGRVAVLRGGKYSVEVDVITDSG-FGRFAAPIDENPSLYIAEAHR--------------AVSEVDEIIGPELI 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 81 GFDVTEQNAIDQLLIELDGTENKGKLGANAILGVSMACARAAADFLQIPLYQYLGGFNSKTLPVPMMNIVNgGEHADNNV 160
Cdd:PRK08350 66 GFDASEQELIDSYLWEIDGTEDFSHIGANTALAVSVAVAKAAANSKNMPLYSYIGGTFTTELPVPILEFAE-DENFEYYV 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 161 DIQEFMIMpvgapnfrealrmgAQIFHSLKSVLSAkglntavgdeggfapnlgSNEEALQTIVEAIEKAGFKPGEEVKLA 240
Cdd:PRK08350 145 LVRDLMEI--------------TDVVDAVNKILEN------------------SKEVSLEGLSKASEKAGDELGLEVALG 192
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 241 MDAassefynkedgKYHLSGEGVVktsaemvdwyeELVSKYPIISIEDGLDEndweghKLLTERLG--KKVQLVGDDLFV 318
Cdd:PRK08350 193 IAQ-----------KREMETEKVL-----------NLVEDNNIAYIKPIGDE------ELFLELIAgtHGVFIDGEYLFR 244
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 319 TNTKklsegIKNGVGNSILIKVNQIGTLTETFDAIEMAKRAGYTAVISHRSGETEDSTIADIAVATNAGQIKTgapsRTD 398
Cdd:PRK08350 245 TRNI-----LDRRYYNALSIKPINLGTLTDLYNLVNDVKSERITPILAEAKYESADEALPHLAVGLRCPAMLI----HKD 315
|
410
....*....|....*..
gi 489321005 399 RVAKYNQLLRIEDQLAE 415
Cdd:PRK08350 316 SVEKINELNRIAEDLGE 332
|
|
| enolase_like |
cd00308 |
Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is ... |
193-391 |
5.04e-15 |
|
Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion. Enolase superfamily contains different enzymes, like enolases, glutarate-, fucanate- and galactonate dehydratases, o-succinylbenzoate synthase, N-acylamino acid racemase, L-alanine-DL-glutamate epimerase, mandelate racemase, muconate lactonizing enzyme and 3-methylaspartase.
Pssm-ID: 238188 [Multi-domain] Cd Length: 229 Bit Score: 73.90 E-value: 5.04e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 193 LSAKGLNTAVGDEGGFAPN----LGSNEEALQTIVEAIekagfkpGEEVKLAMDAASSEFYNkedgkyhlsgegvvktsa 268
Cdd:cd00308 54 LAAKALGVPLAELLGGGSRdrvpAYGSIERVRAVREAF-------GPDARLAVDANGAWTPK------------------ 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 269 EMVDWYEELvSKYPIISIEDGLDENDWEGHKLLTERLGkkVQLVGDDLFVTNTKKLsEGIKNGVGNSILIKVNQIGTLTE 348
Cdd:cd00308 109 EAIRLIRAL-EKYGLAWIEEPCAPDDLEGYAALRRRTG--IPIAADESVTTVDDAL-EALELGAVDILQIKPTRVGGLTE 184
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 489321005 349 TFDAIEMAKRAGYTAVISHRSG-ETEDSTIADIAVAT-NAGQIKT 391
Cdd:cd00308 185 SRRAADLAEAFGIRVMVHGTLEsSIGTAAALHLAAALpNDRAIET 229
|
|
| PTZ00378 |
PTZ00378 |
hypothetical protein; Provisional |
77-413 |
2.87e-08 |
|
hypothetical protein; Provisional
Pssm-ID: 173571 [Multi-domain] Cd Length: 518 Bit Score: 55.65 E-value: 2.87e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 77 PELLGFDVTEQNAIDQLLIELDGTENKGKLGANAILGVSMACARAAADFLQIPLYQYLGGF-----NSKTLPVPMMNIV- 150
Cdd:PTZ00378 117 PRLLQLGARDQREFDSTLRAALSTSPLANVGSAVQWALSIVASLAAARCRSVPLFQYLRALfgsltSVETFSMPQLCITf 196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 151 ----NGGEHADNNVDIQEFMIMPVGAPnFREALRMGAQIFHSLksvlsAKGLNTAVGDEGGFAPNLGSN-EEALQTIVEA 225
Cdd:PTZ00378 197 fgpgNPSTARLALKSVLFSPVMPSGTV-LRERMQKIFAAFHHF-----CQSHNSSVRSDGSLHWDGFANlTDAVKLATEA 270
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 226 IEKAGFKPGEEV--KLAMDAASSEF--YNKEDGK------------YHL-SGEGVVkTSAEMVDWYEELVSKYP--IISI 286
Cdd:PTZ00378 271 LRAVQLTPGTDVclGLRMAASTTRVpaTAVADGGawkeakddcevlYSLfPGEPDV-TGDQLSEYVREQLQAVPdiVVYV 349
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 287 EDGLDENDWEGHKLLTERLGKKVQLVGDDLFV-TNTKKLSEGIKNGVGNSILIKVNQIGTLTETFDAIEMAKR-AGYTAV 364
Cdd:PTZ00378 350 EDTHCDEDTFGLQRLQAALGDSIVLSGVDVYArSEYKKVESGLRGLWTSNIVLNPCAIGTLSDVVEIVRAVGEdEGRAVT 429
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 489321005 365 ISHRSGETEDSTIADIAVATNAGQIKTGAPSRTDRVAKYNQLLRIEDQL 413
Cdd:PTZ00378 430 VLVQTLAGNAATAAHLAVAMGARFLCSGGLFSAHQCEVVSQLASRQDEL 478
|
|
| RspA |
COG4948 |
L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily [Cell wall/membrane ... |
23-360 |
4.55e-07 |
|
L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily [Cell wall/membrane/envelope biogenesis, General function prediction only]; L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Pssm-ID: 443975 [Multi-domain] Cd Length: 359 Bit Score: 51.36 E-value: 4.55e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 23 VEVYTETGAFGRALVPSGAStgeyeavelrdgdkdrylgkGVLTAVNNVNEIIAPELLGFDVTEQNAIDQLLieldgtEN 102
Cdd:COG4948 34 VRVETDDGITGWGEAVPGGT--------------------GAEAVAAALEEALAPLLIGRDPLDIEALWQRL------YR 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 103 KGKLGANAILGVSMACARAAADFLQIPLYQYLGGFNSKTLPVpmmNIVNGgehadnNVDIQEFMimpvgapnfREALRMG 182
Cdd:COG4948 88 ALPGNPAAKAAVDMALWDLLGKALGVPVYQLLGGKVRDRVPV---YATLG------IDTPEEMA---------EEAREAV 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 183 AQIFHSLKSVLSAKGLNTAVgdeggfapnlgsneEALQTIVEAIekagfkpGEEVKLAMDAassefyNkedGKYHLsgeg 262
Cdd:COG4948 150 ARGFRALKLKVGGPDPEEDV--------------ERVRAVREAV-------GPDARLRVDA------N---GAWTL---- 195
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 263 vvKTSAEMVDWYEElvskYPIISIEDGLDENDWEGHKLLTERLGkkVQLVGDDLFVT--NTKKLsegIKNGVGNSILIKV 340
Cdd:COG4948 196 --EEAIRLLRALED----LGLEWIEQPLPAEDLEGLAELRRATP--VPIAADESLTSraDFRRL---IEAGAVDIVNIKL 264
|
330 340
....*....|....*....|
gi 489321005 341 NQIGTLTETFDAIEMAKRAG 360
Cdd:COG4948 265 SKVGGLTEALRIAALAEAHG 284
|
|
| MLE |
cd03318 |
Muconate Lactonizing Enzyme (MLE), an homooctameric enzyme, catalyses the conversion of cis, ... |
21-144 |
4.81e-04 |
|
Muconate Lactonizing Enzyme (MLE), an homooctameric enzyme, catalyses the conversion of cis,cis-muconate (CCM) to muconolactone (ML) in the catechol branch of the beta-ketoadipate pathway. This pathway is used in soil microbes to breakdown lignin-derived aromatics, catechol and protocatechuate, to citric acid cycle intermediates. Some bacterial species are also capable of dehalogenating chloroaromatic compounds by the action of chloromuconate lactonizing enzymes (Cl-MLEs). MLEs are members of the enolase superfamily characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and that is stabilized by coordination to the essential Mg2+ ion.
Pssm-ID: 239434 [Multi-domain] Cd Length: 365 Bit Score: 41.92 E-value: 4.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 21 VEVEVYTETGA--FGRALVPSGASTGeYEAVElrdgdkdrylgkgvlTAVNNVNEIIAPELLGFDVTEQNAIDQlliELD 98
Cdd:cd03318 31 VLVRLTTSDGVvgIGEATTPGGPAWG-GESPE---------------TIKAIIDRYLAPLLIGRDATNIGAAMA---LLD 91
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 489321005 99 GTEnKGKLGANAilGVSMACARAAADFLQIPLYQYLGGFNSKTLPV 144
Cdd:cd03318 92 RAV-AGNLFAKA--AIEMALLDAQGRRLGLPVSELLGGRVRDSLPV 134
|
|
| MR_like |
cd03316 |
Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup ... |
23-306 |
4.63e-03 |
|
Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues, a Lys-X-Lys motif and a conserved histidine-aspartate dyad. Members of the MR subgroup are mandelate racemase, D-glucarate/L-idarate dehydratase (GlucD), D-altronate/D-mannonate dehydratase , D-galactonate dehydratase (GalD) , D-gluconate dehydratase (GlcD), and L-rhamnonate dehydratase (RhamD).
Pssm-ID: 239432 [Multi-domain] Cd Length: 357 Bit Score: 39.13 E-value: 4.63e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 23 VEVYTETGAFGralvpsgasTGEYeavelrdgdkdrYLGKGVLTAVNNVNEIIAPELLGFDVTEQNAIDQLLieLDGTEN 102
Cdd:cd03316 29 VRVTTDDGITG---------WGEA------------YPGGRPSAVAAAIEDLLAPLLIGRDPLDIERLWEKL--YRRLFW 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 103 KGKLG--ANAILGVSMAC----ARAAadflQIPLYQYLGGFNSKTLPVpmmnIVNGGEHADNNVDIQEFMimpvgapnfR 176
Cdd:cd03316 86 RGRGGvaMAAISAVDIALwdikGKAA----GVPVYKLLGGKVRDRVRV----YASGGGYDDSPEELAEEA---------K 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 177 EALRMGaqiFHSLKsvlsakglnTAVGDEGGFAPNLGSNEEALQTIVEAIekagfkpGEEVKLAMDAASSefYNkedgky 256
Cdd:cd03316 149 RAVAEG---FTAVK---------LKVGGPDSGGEDLREDLARVRAVREAV-------GPDVDLMVDANGR--WD------ 201
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 489321005 257 hlsgegvVKTSAEMVDWYEElvskYPIISIEDGLDENDWEGHKLLTERLG 306
Cdd:cd03316 202 -------LAEAIRLARALEE----YDLFWFEEPVPPDDLEGLARLRQATS 240
|
|
| NAAAR |
cd03317 |
N-acylamino acid racemase (NAAAR), an octameric enzyme that catalyzes the racemization of ... |
286-399 |
4.96e-03 |
|
N-acylamino acid racemase (NAAAR), an octameric enzyme that catalyzes the racemization of N-acylamino acids. NAAARs act on a broad range of N-acylamino acids rather than amino acids. Enantiopure amino acids are of industrial interest as chiral building blocks for antibiotics, herbicides, and drugs. NAAAR is a member of the enolase superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion.
Pssm-ID: 239433 [Multi-domain] Cd Length: 354 Bit Score: 38.75 E-value: 4.96e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489321005 286 IEDGLDENDWEGHKLLTERLGKKVQLvgdDLFVTNTKKLSEGIKNGVGNSILIKVNQIGTLTETFDAIEMAKRAGytavI 365
Cdd:cd03317 208 IEQPLAADDLIDHAELQKLLKTPICL---DESIQSAEDARKAIELGACKIINIKPGRVGGLTEALKIHDLCQEHG----I 280
|
90 100 110
....*....|....*....|....*....|....*..
gi 489321005 366 SHRSG---ETEDSTIADIAVATNAGQIKTGAPSRTDR 399
Cdd:cd03317 281 PVWCGgmlESGIGRAHNVALASLPNFTYPGDISASSR 317
|
|
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