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Conserved domains on  [gi|489182425|ref|WP_003091873|]
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MULTISPECIES: cupin domain-containing protein [Pseudomonas]

Protein Classification

cupin domain-containing protein( domain architecture ID 10007407)

cupin domain-containing protein similar to Thermotoga maritima TM1112

CATH:  2.60.120.10
PubMed:  9573603
SCOP:  4003965

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG3450 COG3450
Predicted enzyme of the cupin superfamily [General function prediction only];
8-112 1.92e-37

Predicted enzyme of the cupin superfamily [General function prediction only];


:

Pssm-ID: 442673  Cd Length: 108  Bit Score: 122.40  E-value: 1.92e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489182425   8 NTAGADLGAASPVAVPLGEPVAQTRAYAVERTDQVETGIWECTPGRWRRQIVEQEFCHFLQGRCTFTPDGGETIRIEAGD 87
Cdd:COG3450    4 DAVEPESDPPAPERILEGDPSARTWNLFTSPDGGVSAGVWECTPGKFRWDYDEDEFCYILEGRVTVTDDDGEPVEFGAGD 83

                         90       100
                 ....*....|....*....|....*
gi 489182425  88 ALLLPENSLGVWDVQETVRKSYVII 112
Cdd:COG3450   84 SFVFPAGFKGTWEVLETVRKHYVIR 108
 
Name Accession Description Interval E-value
COG3450 COG3450
Predicted enzyme of the cupin superfamily [General function prediction only];
8-112 1.92e-37

Predicted enzyme of the cupin superfamily [General function prediction only];


Pssm-ID: 442673  Cd Length: 108  Bit Score: 122.40  E-value: 1.92e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489182425   8 NTAGADLGAASPVAVPLGEPVAQTRAYAVERTDQVETGIWECTPGRWRRQIVEQEFCHFLQGRCTFTPDGGETIRIEAGD 87
Cdd:COG3450    4 DAVEPESDPPAPERILEGDPSARTWNLFTSPDGGVSAGVWECTPGKFRWDYDEDEFCYILEGRVTVTDDDGEPVEFGAGD 83

                         90       100
                 ....*....|....*....|....*
gi 489182425  88 ALLLPENSLGVWDVQETVRKSYVII 112
Cdd:COG3450   84 SFVFPAGFKGTWEVLETVRKHYVIR 108
cupin_TM1112-like cd02227
Thermotoga maritima TM1112 and related proteins, cupin domain; This family includes bacterial ...
 44-111 6.07e-32

Thermotoga maritima TM1112 and related proteins, cupin domain; This family includes bacterial and plant proteins homologous to TM1112, a Thermotoga maritima protein of unknown function with a cupin beta barrel domain. TM1112 (also known as DUF861) is a subfamily of RmlC-like cupins with a conserved "jelly roll-like" beta-barrel fold; structures indicate that a monomer is the biologically-relevant form.


Pssm-ID: 380356 [Multi-domain]  Cd Length: 69  Bit Score: 106.90  E-value: 6.07e-32
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489182425  44 TGIWECTPGRWRRQIVEQEFCHFLQGRCTFTPDGGETIRIEAGDALLLPENSLGVWDVQETVRKSYVI 111
Cdd:cd02227    2 WGIWECTPGKFPWNYDEDEFCYILEGEVRVTPEDGEPVTFKAGDLVVFPAGFSGTWEVLEPVRKHYVF 69
Cupin_3 pfam05899
EutQ-like cupin domain; This entry represents the cupin domain, with a conserved jelly ...
 36-109 8.74e-31

EutQ-like cupin domain; This entry represents the cupin domain, with a conserved jelly roll-like beta-barrel fold capable of homodimerization found in bacteria, plant and fungi. It is present in EutQ family from the eut operon, involved in ethanolamine degradation. EutQ is essential during anoxic growth and has acetate kinase activity. The cupin domain from EutQ does not possess the His residues responsible for metal coordination in other classes of cupins. This domain is also found in (S)-ureidoglycine aminohydrolase (UGlyAH) from E.coli, which is involved in the anaerobic nitrogen utilization via the assimilation of allantoin. It catalyzes the deamination of allantoin to produce S-ureidoglycolate and ammonia from S-ureidoglycine.


Pssm-ID: 399116 [Multi-domain]  Cd Length: 74  Bit Score: 104.29  E-value: 8.74e-31
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489182425   36 VERTDQVETGIWECTPGRWRRQIVEQEFCHFLQGRCTFTPDGGETIRIEAGDALLLPENSLGVWDVQETVRKSY 109
Cdd:pfam05899   1 LSPLGVFSWGIWECTPGKFRWTYEEDETCYILSGEVTVTPEGGKTVTLRAGDLVVLPKGLSGTWDVLETVRKHY 74
 
Name Accession Description Interval E-value
COG3450 COG3450
Predicted enzyme of the cupin superfamily [General function prediction only];
8-112 1.92e-37

Predicted enzyme of the cupin superfamily [General function prediction only];


Pssm-ID: 442673  Cd Length: 108  Bit Score: 122.40  E-value: 1.92e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489182425   8 NTAGADLGAASPVAVPLGEPVAQTRAYAVERTDQVETGIWECTPGRWRRQIVEQEFCHFLQGRCTFTPDGGETIRIEAGD 87
Cdd:COG3450    4 DAVEPESDPPAPERILEGDPSARTWNLFTSPDGGVSAGVWECTPGKFRWDYDEDEFCYILEGRVTVTDDDGEPVEFGAGD 83

                         90       100
                 ....*....|....*....|....*
gi 489182425  88 ALLLPENSLGVWDVQETVRKSYVII 112
Cdd:COG3450   84 SFVFPAGFKGTWEVLETVRKHYVIR 108
cupin_TM1112-like cd02227
Thermotoga maritima TM1112 and related proteins, cupin domain; This family includes bacterial ...
 44-111 6.07e-32

Thermotoga maritima TM1112 and related proteins, cupin domain; This family includes bacterial and plant proteins homologous to TM1112, a Thermotoga maritima protein of unknown function with a cupin beta barrel domain. TM1112 (also known as DUF861) is a subfamily of RmlC-like cupins with a conserved "jelly roll-like" beta-barrel fold; structures indicate that a monomer is the biologically-relevant form.


Pssm-ID: 380356 [Multi-domain]  Cd Length: 69  Bit Score: 106.90  E-value: 6.07e-32
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489182425  44 TGIWECTPGRWRRQIVEQEFCHFLQGRCTFTPDGGETIRIEAGDALLLPENSLGVWDVQETVRKSYVI 111
Cdd:cd02227    2 WGIWECTPGKFPWNYDEDEFCYILEGEVRVTPEDGEPVTFKAGDLVVFPAGFSGTWEVLEPVRKHYVF 69
Cupin_3 pfam05899
EutQ-like cupin domain; This entry represents the cupin domain, with a conserved jelly ...
 36-109 8.74e-31

EutQ-like cupin domain; This entry represents the cupin domain, with a conserved jelly roll-like beta-barrel fold capable of homodimerization found in bacteria, plant and fungi. It is present in EutQ family from the eut operon, involved in ethanolamine degradation. EutQ is essential during anoxic growth and has acetate kinase activity. The cupin domain from EutQ does not possess the His residues responsible for metal coordination in other classes of cupins. This domain is also found in (S)-ureidoglycine aminohydrolase (UGlyAH) from E.coli, which is involved in the anaerobic nitrogen utilization via the assimilation of allantoin. It catalyzes the deamination of allantoin to produce S-ureidoglycolate and ammonia from S-ureidoglycine.


Pssm-ID: 399116 [Multi-domain]  Cd Length: 74  Bit Score: 104.29  E-value: 8.74e-31
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489182425   36 VERTDQVETGIWECTPGRWRRQIVEQEFCHFLQGRCTFTPDGGETIRIEAGDALLLPENSLGVWDVQETVRKSY 109
Cdd:pfam05899   1 LSPLGVFSWGIWECTPGKFRWTYEEDETCYILSGEVTVTPEGGKTVTLRAGDLVVLPKGLSGTWDVLETVRKHY 74
cupin_YkgD-like_N cd06995
AraC/XylS family transcriptional regulators similar to Escherichia coli YkgD, N-terminal cupin ...
 67-95 3.05e-04

AraC/XylS family transcriptional regulators similar to Escherichia coli YkgD, N-terminal cupin domain; This family contains mostly bacterial proteins containing an AraC/XylS family helix-turn-helix (HTH) DNA-binding domain C-terminal to a cupin domain, and may be possible transcriptional regulators. Included in this family is YkgD, an uncharacterized Escherichia coli protein thought to be a transcriptional regulator. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.


Pssm-ID: 380399  Cd Length: 114  Bit Score: 37.31  E-value: 3.05e-04
                         10        20
                 ....*....|....*....|....*....
gi 489182425  67 LQGRCTFTPDGGETIRIEAGDALLLPENS 95
Cdd:cd06995   44 LQGECRLELPGGESLTLSPGDVVLLPQGS 72
COG3837 COG3837
Uncharacterized conserved protein, cupin superfamily [Function unknown];
39-92 1.98e-03

Uncharacterized conserved protein, cupin superfamily [Function unknown];


Pssm-ID: 443048 [Multi-domain]  Cd Length: 115  Bit Score: 34.99  E-value: 1.98e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 489182425  39 TDQVETGIWECTPGRW----RRQIVEQEFCHFLQGRCTFTpDGGETIRIEAGDALLLP 92
Cdd:COG3837   25 LTRLGVNLITLPPGASsspyHAHSAEEEFVYVLEGELTLR-IGGEEYVLEPGDSVGFP 81
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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