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Conserved domains on  [gi|489027145|ref|WP_002937550|]
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MULTISPECIES: PadR family transcriptional regulator [Streptococcus]

Protein Classification

PadR family transcriptional regulator( domain architecture ID 11447737)

PadR family transcriptional regulator similar to the phenolic acid decarboxylation repressor, which is a transcription factor that represses genes associated with the phenolic acid stress response in gram-positive bacteria

Gene Ontology:  GO:0003677|GO:0003700
PubMed:  10679470|10908318|10473770|15808743|8831795

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PadR COG1695
DNA-binding transcriptional regulator, PadR family [Transcription];
10-96 1.05e-22

DNA-binding transcriptional regulator, PadR family [Transcription];


:

Pssm-ID: 441301  Cd Length: 102  Bit Score: 84.22  E-value: 1.05e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489027145  10 TEFLIMAILESDDSYGYEICQTIKLIAN----IKESALYPILKRLEQNDFLTTYSQEY-QGRMRKYYSLTQLGHEELVRL 84
Cdd:COG1695   10 LELLILALLAEGPMYGYEIIKELEERSGgfwkVSEGTLYPALKRLEKEGLVESEWEESeGGPRRKYYRLTEAGREELAEW 89

                         90
                 ....*....|..
gi 489027145  85 KDDWDTYTNTIN 96
Cdd:COG1695   90 LEEWEKLAEALE 101
 
Name Accession Description Interval E-value
PadR COG1695
DNA-binding transcriptional regulator, PadR family [Transcription];
10-96 1.05e-22

DNA-binding transcriptional regulator, PadR family [Transcription];


Pssm-ID: 441301  Cd Length: 102  Bit Score: 84.22  E-value: 1.05e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489027145  10 TEFLIMAILESDDSYGYEICQTIKLIAN----IKESALYPILKRLEQNDFLTTYSQEY-QGRMRKYYSLTQLGHEELVRL 84
Cdd:COG1695   10 LELLILALLAEGPMYGYEIIKELEERSGgfwkVSEGTLYPALKRLEKEGLVESEWEESeGGPRRKYYRLTEAGREELAEW 89

                         90
                 ....*....|..
gi 489027145  85 KDDWDTYTNTIN 96
Cdd:COG1695   90 LEEWEKLAEALE 101
PadR pfam03551
Transcriptional regulator PadR-like family; Members of this family are transcriptional ...
 14-81 4.50e-15

Transcriptional regulator PadR-like family; Members of this family are transcriptional regulators that appear to be related to the pfam01047 family. This family includes PadR, a protein that is involved in negative regulation of phenolic acid metabolism.


Pssm-ID: 397561  Cd Length: 74  Bit Score: 64.19  E-value: 4.50e-15
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489027145   14 IMAILESDDSYGYEICQTIKLIAN----IKESALYPILKRLEQNDFLTTYSQEY-QGRMRKYYSLTQLGHEEL 81
Cdd:pfam03551   1 VLAVLGEQPRYGYEIIKELEELSGgfwrPSEGTLYPILKRLEKEGLVESEWVDSgGGPPRKYYRLTDAGRREL 73
padR_acidobact TIGR03433
transcriptional regulator, Acidobacterial, PadR-family; Members of this protein family are ...
 11-100 2.01e-11

transcriptional regulator, Acidobacterial, PadR-family; Members of this protein family are putative transcriptional regulators of the PadR family, as found in species of the Acidobacteria. This family of proteins has expanded greatly in this lineage, and where it regularly is found in the vicinity of a putative transporter protein [Regulatory functions, DNA interactions]


Pssm-ID: 163261  Cd Length: 100  Bit Score: 55.64  E-value: 2.01e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489027145   11 EFLIMAILESDDSYGYEICQTIKLIAN----IKESALYPILKRLEQNDFLT-TYSQEYQGRMRKYYSLTQLGHEELVRLK 85
Cdd:TIGR03433   6 DLLILKTLSLGPLHGYGIAQRIQQISEdvlqVEEGSLYPALHRLERRGWIAaEWGESENNRRAKFYRLTAAGRKQLAAET 85

                          90
                  ....*....|....*
gi 489027145   86 DDWDTYTNTINGIIE 100
Cdd:TIGR03433  86 ESWARLSAAIARVLG 100
lstR PRK09416
PadR family transcriptional regulator;
13-101 2.42e-07

PadR family transcriptional regulator;


Pssm-ID: 181836  Cd Length: 135  Bit Score: 45.93  E-value: 2.42e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489027145  13 LIMAILeSDDSYGYEICQTI--KLIANIK--ESALYPILKRLEQNDFLTTysqEYQGRMRKYYSLTQLGHEELVRLKDDW 88
Cdd:PRK09416  47 AILQLL-MNEKTGYELLQLLrqRGILTFEgnEGSLYTLLHRLEQNRFIQS---SWDHEGAKYYQLTDKGNKMLRKAEKNA 122

                         90
                 ....*....|...
gi 489027145  89 DTYTNTINGIIEG 101
Cdd:PRK09416 123 TKARFILKGLVQE 135
 
Name Accession Description Interval E-value
PadR COG1695
DNA-binding transcriptional regulator, PadR family [Transcription];
10-96 1.05e-22

DNA-binding transcriptional regulator, PadR family [Transcription];


Pssm-ID: 441301  Cd Length: 102  Bit Score: 84.22  E-value: 1.05e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489027145  10 TEFLIMAILESDDSYGYEICQTIKLIAN----IKESALYPILKRLEQNDFLTTYSQEY-QGRMRKYYSLTQLGHEELVRL 84
Cdd:COG1695   10 LELLILALLAEGPMYGYEIIKELEERSGgfwkVSEGTLYPALKRLEKEGLVESEWEESeGGPRRKYYRLTEAGREELAEW 89

                         90
                 ....*....|..
gi 489027145  85 KDDWDTYTNTIN 96
Cdd:COG1695   90 LEEWEKLAEALE 101
PadR pfam03551
Transcriptional regulator PadR-like family; Members of this family are transcriptional ...
 14-81 4.50e-15

Transcriptional regulator PadR-like family; Members of this family are transcriptional regulators that appear to be related to the pfam01047 family. This family includes PadR, a protein that is involved in negative regulation of phenolic acid metabolism.


Pssm-ID: 397561  Cd Length: 74  Bit Score: 64.19  E-value: 4.50e-15
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489027145   14 IMAILESDDSYGYEICQTIKLIAN----IKESALYPILKRLEQNDFLTTYSQEY-QGRMRKYYSLTQLGHEEL 81
Cdd:pfam03551   1 VLAVLGEQPRYGYEIIKELEELSGgfwrPSEGTLYPILKRLEKEGLVESEWVDSgGGPPRKYYRLTDAGRREL 73
padR_acidobact TIGR03433
transcriptional regulator, Acidobacterial, PadR-family; Members of this protein family are ...
 11-100 2.01e-11

transcriptional regulator, Acidobacterial, PadR-family; Members of this protein family are putative transcriptional regulators of the PadR family, as found in species of the Acidobacteria. This family of proteins has expanded greatly in this lineage, and where it regularly is found in the vicinity of a putative transporter protein [Regulatory functions, DNA interactions]


Pssm-ID: 163261  Cd Length: 100  Bit Score: 55.64  E-value: 2.01e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489027145   11 EFLIMAILESDDSYGYEICQTIKLIAN----IKESALYPILKRLEQNDFLT-TYSQEYQGRMRKYYSLTQLGHEELVRLK 85
Cdd:TIGR03433   6 DLLILKTLSLGPLHGYGIAQRIQQISEdvlqVEEGSLYPALHRLERRGWIAaEWGESENNRRAKFYRLTAAGRKQLAAET 85

                          90
                  ....*....|....*
gi 489027145   86 DDWDTYTNTINGIIE 100
Cdd:TIGR03433  86 ESWARLSAAIARVLG 100
lstR PRK09416
PadR family transcriptional regulator;
13-101 2.42e-07

PadR family transcriptional regulator;


Pssm-ID: 181836  Cd Length: 135  Bit Score: 45.93  E-value: 2.42e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489027145  13 LIMAILeSDDSYGYEICQTI--KLIANIK--ESALYPILKRLEQNDFLTTysqEYQGRMRKYYSLTQLGHEELVRLKDDW 88
Cdd:PRK09416  47 AILQLL-MNEKTGYELLQLLrqRGILTFEgnEGSLYTLLHRLEQNRFIQS---SWDHEGAKYYQLTDKGNKMLRKAEKNA 122

                         90
                 ....*....|...
gi 489027145  89 DTYTNTINGIIEG 101
Cdd:PRK09416 123 TKARFILKGLVQE 135
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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