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Conserved domains on  [gi|489011712|ref|WP_002922251|]
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MULTISPECIES: histidinol-phosphate transaminase [Campylobacter]

Protein Classification

histidinol-phosphate transaminase( domain architecture ID 11490209)

histidinol-phosphate transaminase is a pyridoxal phosphate (PLP)-dependent aminotransferase that catalyzes the reversible transfer of the amino group from glutamate to imidazole acetol-phosphate producing 2-oxoglutarate and histidinol phosphate

CATH:  3.40.640.10
EC:  2.6.1.9
Gene Symbol:  hisC
Gene Ontology:  GO:0004400|GO:0030170|GO:0000105
PubMed:  10800595
SCOP:  4000670

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
hisC TIGR01141
histidinol-phosphate aminotransferase; Alternate names: histidinol-phosphate transaminase; ...
 4-362 7.06e-156

histidinol-phosphate aminotransferase; Alternate names: histidinol-phosphate transaminase; imidazole acetol-phosphate transaminase Histidinol-phosphate aminotransferase is a pyridoxal-phosphate dependent enzyme. [Amino acid biosynthesis, Histidine family]


:

Pssm-ID: 273467  Cd Length: 350  Bit Score: 441.71  E-value: 7.06e-156
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712    4 NEFLNHLSNYEPGkdieviAKEYGVKEVIKLASNENPFGTPPKAIECLRQNANKAHLYPDDSMIELKSTLAQKYKVQNEN 83
Cdd:TIGR01141   1 RPDIKNLSPYQPG------ARELGGDEVIKLNSNENPFGPPEKAKEALRAELKKLHRYPDPDPAELKQALADYYGVDPEQ 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712   84 IIIGAGSDQVIEFAIHAKLNSKNAFLQAGVTFAMYEIYAKQCGAKCYKTQSITHNLDEFKKLYETHKDEIKLIFLCLPNN 163
Cdd:TIGR01141  75 ILLGNGSDEIIDLLIRAFLEPGDAVLVPPPTYSMYEISAKIHGAEVVKVPLDEDGQLDLEDILVAIDDKPKLVFLCSPNN 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  164 PLGECLDASEVTKFIKGVEEDCLVVIDAAYNEFASFKDskkhlePCELIKEFDNVLYLGTFSKLYGLGGLRIGYGIADAS 243
Cdd:TIGR01141 155 PTGNLFSRGDIEAVLERTPGDALVVVDEAYGEFSGEPS------TLPLLAEYPNLIVLRTLSKAFGLAGLRIGYAIANAE 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  244 IISAFYKLRAPFNVSNLALKAAVAAMDDDEFTEKTLENNFSQMELYKEFAKKHN-IKIIDSYTNFITYFFDEkNSTDLSE 322
Cdd:TIGR01141 229 IIDALNKVRAPFNLSRLAQAAAIAALRDDDFIEATVEEINAERERLYDGLKKLPgLEVYPSDANFVLIRFPG-DADALFE 307

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|...
gi 489011712  323 KLLKKGIIIRNLKSY-GL--NAIRITIGTSYENERFFTEFDKI 362
Cdd:TIGR01141 308 ALLEKGIIVRDLNSYpGLlpNCLRITVGTREENDRFLAALREI 350
 
Name Accession Description Interval E-value
hisC TIGR01141
histidinol-phosphate aminotransferase; Alternate names: histidinol-phosphate transaminase; ...
 4-362 7.06e-156

histidinol-phosphate aminotransferase; Alternate names: histidinol-phosphate transaminase; imidazole acetol-phosphate transaminase Histidinol-phosphate aminotransferase is a pyridoxal-phosphate dependent enzyme. [Amino acid biosynthesis, Histidine family]


Pssm-ID: 273467  Cd Length: 350  Bit Score: 441.71  E-value: 7.06e-156
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712    4 NEFLNHLSNYEPGkdieviAKEYGVKEVIKLASNENPFGTPPKAIECLRQNANKAHLYPDDSMIELKSTLAQKYKVQNEN 83
Cdd:TIGR01141   1 RPDIKNLSPYQPG------ARELGGDEVIKLNSNENPFGPPEKAKEALRAELKKLHRYPDPDPAELKQALADYYGVDPEQ 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712   84 IIIGAGSDQVIEFAIHAKLNSKNAFLQAGVTFAMYEIYAKQCGAKCYKTQSITHNLDEFKKLYETHKDEIKLIFLCLPNN 163
Cdd:TIGR01141  75 ILLGNGSDEIIDLLIRAFLEPGDAVLVPPPTYSMYEISAKIHGAEVVKVPLDEDGQLDLEDILVAIDDKPKLVFLCSPNN 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  164 PLGECLDASEVTKFIKGVEEDCLVVIDAAYNEFASFKDskkhlePCELIKEFDNVLYLGTFSKLYGLGGLRIGYGIADAS 243
Cdd:TIGR01141 155 PTGNLFSRGDIEAVLERTPGDALVVVDEAYGEFSGEPS------TLPLLAEYPNLIVLRTLSKAFGLAGLRIGYAIANAE 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  244 IISAFYKLRAPFNVSNLALKAAVAAMDDDEFTEKTLENNFSQMELYKEFAKKHN-IKIIDSYTNFITYFFDEkNSTDLSE 322
Cdd:TIGR01141 229 IIDALNKVRAPFNLSRLAQAAAIAALRDDDFIEATVEEINAERERLYDGLKKLPgLEVYPSDANFVLIRFPG-DADALFE 307

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|...
gi 489011712  323 KLLKKGIIIRNLKSY-GL--NAIRITIGTSYENERFFTEFDKI 362
Cdd:TIGR01141 308 ALLEKGIIVRDLNSYpGLlpNCLRITVGTREENDRFLAALREI 350
HisC COG0079
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid ...
 13-362 3.08e-112

Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid transport and metabolism]; Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 439849 [Multi-domain]  Cd Length: 341  Bit Score: 330.56  E-value: 3.08e-112
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  13 YEPGKDIEVIAkeygvkEVIKLASNENPFGTPPKAIECLRQNANKAHLYPDDSMIELKSTLAQKYKVQNENIIIGAGSDQ 92
Cdd:COG0079    3 YVPGGPIEEPE------DIIKLSSNENPYGPPPKVLEAIAAALDALNRYPDPDATALREALAEYYGVPPEQVLVGNGSDE 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  93 VIEFAIHAKLNSKNAFLQAGVTFAMYEIYAKQCGAKCYK---TQSITHNLDEFKKLYEthkDEIKLIFLCLPNNPLGECL 169
Cdd:COG0079   77 LIQLLARAFLGPGDEVLVPEPTFSEYPIAARAAGAEVVEvplDEDFSLDLDALLAAIT---ERTDLVFLCNPNNPTGTLL 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 170 DASEVTKFIKGVEEDCLVVIDAAYNEFASFKDSkkhlePCELIKEFDNVLYLGTFSKLYGLGGLRIGYGIADASIISAFY 249
Cdd:COG0079  154 PREELEALLEALPADGLVVVDEAYAEFVPEEDS-----ALPLLARYPNLVVLRTFSKAYGLAGLRLGYAIASPELIAALR 228

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 250 KLRAPFNVSNLALKAAVAAMDDDEFTEKTLENNFSQME-LYKEFAkKHNIKIIDSYTNFItyFFD-EKNSTDLSEKLLKK 327
Cdd:COG0079  229 RVRGPWNVNSLAQAAALAALEDRAYLEETRARLRAERErLAAALR-ALGLTVYPSQANFV--LVRvPEDAAELFEALLER 305

                        330       340       350
                 ....*....|....*....|....*....|....*.
gi 489011712 328 GIIIRNLKSYGL-NAIRITIGTSYENERFFTEFDKI 362
Cdd:COG0079  306 GILVRDFSSFGLpDYLRITVGTPEENDRLLAALKEI 341
PRK05166 PRK05166
histidinol-phosphate transaminase;
10-363 1.19e-66

histidinol-phosphate transaminase;


Pssm-ID: 179950  Cd Length: 371  Bit Score: 215.00  E-value: 1.19e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  10 LSNYEPGKDIEVIAKEYGVKEVIKLASNENPFGTPPKAIECLRQNANKAHLYPDDSMIELKSTLAQKYKVQNENIIIGAG 89
Cdd:PRK05166  17 LPPYNAGLTIEEVRARYGVPRIAKLGSNENPLGPSPAVRRAFADIAELLRLYPDPQGRALREAIAARTGVPADRIILGNG 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  90 SDQVIEFAIHAKLNSKNAFLQAGVTFAMYEIYAKQCGAKCYK---TQSITHNLDEfkkLYETHKDEIKLIFLCLPNNPLG 166
Cdd:PRK05166  97 SEDLIAVICRAVLRPGDRVVTLYPSFPLHEDYPTMMGARVERvtvTPDLGFDLDA---LCAAVARAPRMLMFSNPSNPVG 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 167 ECLDASEVTKFIKGVEEDCLVVIDAAYNEFASFKDSKKHLepcELIKEFD-NVLYLGTFSKLYGLGGLRIGYGIA-DASI 244
Cdd:PRK05166 174 SWLTADQLARVLDATPPETLIVVDEAYAEYAAGDDYPSAL---TLLKARGlPWIVLRTFSKAYGLAGLRVGYGLVsDPEL 250

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 245 ISAFYKLRAPFNVSNLALKAAVAAMDDDEFTEKTLENNFSQMELYKEFAKKHNIKIIDSYTNFItyFFDEK-NSTDLSEK 323
Cdd:PRK05166 251 VGLLDRVRTPFNVNGAAQAAALAALDDEEHLAKGVALALAERERLKKELAEMGYRIAPSRANFL--FFDARrPASAVAEA 328

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|.
gi 489011712 324 LLKKGIIIRNLKSYGLNA-IRITIGTSYENERFFTEFDKIL 363
Cdd:PRK05166 329 LLRQGVIVKPWKQPGFETfIRVSIGSPEENDHFVAALDKVL 369
AAT_like cd00609
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ...
 32-354 5.78e-60

Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.


Pssm-ID: 99734 [Multi-domain]  Cd Length: 350  Bit Score: 196.79  E-value: 5.78e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  32 IKLASNENPFGTPPKAIECLRQNANKA---HLYPDDSMIELKSTLAQKYKVQN------ENIIIGAGSDQVIEFAIHAKL 102
Cdd:cd00609    1 IDLSIGEPDFPPPPEVLEALAAAALRAgllGYYPDPGLPELREAIAEWLGRRGgvdvppEEIVVTNGAQEALSLLLRALL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 103 NSKNAFLQAGVTFAMYEIYAKQCGAKCYKTQSITHN--LDEFKKLYETHKDEIKLIFLCLPNNPLGECLDASEVTKFIKG 180
Cdd:cd00609   81 NPGDEVLVPDPTYPGYEAAARLAGAEVVPVPLDEEGgfLLDLELLEAAKTPKTKLLYLNNPNNPTGAVLSEEELEELAEL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 181 VEE-DCLVVIDAAYNEFAsfkDSKKHLEPCELIKEFDNVLYLGTFSKLYGLGGLRIGYGIADASIISAFYKLRAPF---N 256
Cdd:cd00609  161 AKKhGILIISDEAYAELV---YDGEPPPALALLDAYERVIVLRSFSKTFGLPGLRIGYLIAPPEELLERLKKLLPYttsG 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 257 VSNLALKAAVAAMDD-DEFTEKTLENNFSQMELYKEFAKKHN--IKIIDSYTNFITYFFDEKNSTDLSEKLLKK-GIIIR 332
Cdd:cd00609  238 PSTLSQAAAAAALDDgEEHLEELRERYRRRRDALLEALKELGplVVVKPSGGFFLWLDLPEGDDEEFLERLLLEaGVVVR 317

                        330       340
                 ....*....|....*....|....*
gi 489011712 333 NLKSYGL---NAIRITIGTSYENER 354
Cdd:cd00609  318 PGSAFGEggeGFVRLSFATPEEELE 342
Aminotran_1_2 pfam00155
Aminotransferase class I and II;
29-355 1.52e-51

Aminotransferase class I and II;


Pssm-ID: 395103 [Multi-domain]  Cd Length: 351  Bit Score: 175.19  E-value: 1.52e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712   29 KEVIKLASNENPFGTPPKAIECLRQNA--NKAHLYPD-DSMIELKSTLAQKYKVQNE-------NIIIGAGSDQVIEFAI 98
Cdd:pfam00155   1 TDKINLGSNEYLGDTLPAVAKAEKDALagGTRNLYGPtDGHPELREALAKFLGRSPVlkldreaAVVFGSGAGANIEALI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712   99 HAKLNSKNAFLQAGVTFAMYEIYAKQCGAKCYK---TQSITHNLDeFKKLYETHKDEIKLIFLCLPNNPLGECLDASEVT 175
Cdd:pfam00155  81 FLLANPGDAILVPAPTYASYIRIARLAGGEVVRyplYDSNDFHLD-FDALEAALKEKPKVVLHTSPHNPTGTVATLEELE 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  176 KFIKGVEE-DCLVVIDAAYNEFASfkDSKKHLEPCELIKEFDNVLYLGTFSKLYGLGGLRIGYGIADASIISAFYKLRAP 254
Cdd:pfam00155 160 KLLDLAKEhNILLLVDEAYAGFVF--GSPDAVATRALLAEGPNLLVVGSFSKAFGLAGWRVGYILGNAAVISQLRKLARP 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  255 FNVSNLALKAAVAAMDDDEFTEKTLENN-----FSQMELYKEFAKKhNIKIIDSYTNFITY-FFDEKNSTDLSEKLLK-K 327
Cdd:pfam00155 238 FYSSTHLQAAAAAALSDPLLVASELEEMrqrikERRDYLRDGLQAA-GLSVLPSQAGFFLLtGLDPETAKELAQVLLEeV 316

                         330       340       350
                  ....*....|....*....|....*....|.
gi 489011712  328 GIIIRNLKSYGL-NAIRITI--GTSYENERF 355
Cdd:pfam00155 317 GVYVTPGSSPGVpGWLRITVagGTEEELEEL 347
 
Name Accession Description Interval E-value
hisC TIGR01141
histidinol-phosphate aminotransferase; Alternate names: histidinol-phosphate transaminase; ...
 4-362 7.06e-156

histidinol-phosphate aminotransferase; Alternate names: histidinol-phosphate transaminase; imidazole acetol-phosphate transaminase Histidinol-phosphate aminotransferase is a pyridoxal-phosphate dependent enzyme. [Amino acid biosynthesis, Histidine family]


Pssm-ID: 273467  Cd Length: 350  Bit Score: 441.71  E-value: 7.06e-156
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712    4 NEFLNHLSNYEPGkdieviAKEYGVKEVIKLASNENPFGTPPKAIECLRQNANKAHLYPDDSMIELKSTLAQKYKVQNEN 83
Cdd:TIGR01141   1 RPDIKNLSPYQPG------ARELGGDEVIKLNSNENPFGPPEKAKEALRAELKKLHRYPDPDPAELKQALADYYGVDPEQ 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712   84 IIIGAGSDQVIEFAIHAKLNSKNAFLQAGVTFAMYEIYAKQCGAKCYKTQSITHNLDEFKKLYETHKDEIKLIFLCLPNN 163
Cdd:TIGR01141  75 ILLGNGSDEIIDLLIRAFLEPGDAVLVPPPTYSMYEISAKIHGAEVVKVPLDEDGQLDLEDILVAIDDKPKLVFLCSPNN 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  164 PLGECLDASEVTKFIKGVEEDCLVVIDAAYNEFASFKDskkhlePCELIKEFDNVLYLGTFSKLYGLGGLRIGYGIADAS 243
Cdd:TIGR01141 155 PTGNLFSRGDIEAVLERTPGDALVVVDEAYGEFSGEPS------TLPLLAEYPNLIVLRTLSKAFGLAGLRIGYAIANAE 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  244 IISAFYKLRAPFNVSNLALKAAVAAMDDDEFTEKTLENNFSQMELYKEFAKKHN-IKIIDSYTNFITYFFDEkNSTDLSE 322
Cdd:TIGR01141 229 IIDALNKVRAPFNLSRLAQAAAIAALRDDDFIEATVEEINAERERLYDGLKKLPgLEVYPSDANFVLIRFPG-DADALFE 307

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|...
gi 489011712  323 KLLKKGIIIRNLKSY-GL--NAIRITIGTSYENERFFTEFDKI 362
Cdd:TIGR01141 308 ALLEKGIIVRDLNSYpGLlpNCLRITVGTREENDRFLAALREI 350
HisC COG0079
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid ...
 13-362 3.08e-112

Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid transport and metabolism]; Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 439849 [Multi-domain]  Cd Length: 341  Bit Score: 330.56  E-value: 3.08e-112
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  13 YEPGKDIEVIAkeygvkEVIKLASNENPFGTPPKAIECLRQNANKAHLYPDDSMIELKSTLAQKYKVQNENIIIGAGSDQ 92
Cdd:COG0079    3 YVPGGPIEEPE------DIIKLSSNENPYGPPPKVLEAIAAALDALNRYPDPDATALREALAEYYGVPPEQVLVGNGSDE 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  93 VIEFAIHAKLNSKNAFLQAGVTFAMYEIYAKQCGAKCYK---TQSITHNLDEFKKLYEthkDEIKLIFLCLPNNPLGECL 169
Cdd:COG0079   77 LIQLLARAFLGPGDEVLVPEPTFSEYPIAARAAGAEVVEvplDEDFSLDLDALLAAIT---ERTDLVFLCNPNNPTGTLL 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 170 DASEVTKFIKGVEEDCLVVIDAAYNEFASFKDSkkhlePCELIKEFDNVLYLGTFSKLYGLGGLRIGYGIADASIISAFY 249
Cdd:COG0079  154 PREELEALLEALPADGLVVVDEAYAEFVPEEDS-----ALPLLARYPNLVVLRTFSKAYGLAGLRLGYAIASPELIAALR 228

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 250 KLRAPFNVSNLALKAAVAAMDDDEFTEKTLENNFSQME-LYKEFAkKHNIKIIDSYTNFItyFFD-EKNSTDLSEKLLKK 327
Cdd:COG0079  229 RVRGPWNVNSLAQAAALAALEDRAYLEETRARLRAERErLAAALR-ALGLTVYPSQANFV--LVRvPEDAAELFEALLER 305

                        330       340       350
                 ....*....|....*....|....*....|....*.
gi 489011712 328 GIIIRNLKSYGL-NAIRITIGTSYENERFFTEFDKI 362
Cdd:COG0079  306 GILVRDFSSFGLpDYLRITVGTPEENDRLLAALKEI 341
PRK05166 PRK05166
histidinol-phosphate transaminase;
10-363 1.19e-66

histidinol-phosphate transaminase;


Pssm-ID: 179950  Cd Length: 371  Bit Score: 215.00  E-value: 1.19e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  10 LSNYEPGKDIEVIAKEYGVKEVIKLASNENPFGTPPKAIECLRQNANKAHLYPDDSMIELKSTLAQKYKVQNENIIIGAG 89
Cdd:PRK05166  17 LPPYNAGLTIEEVRARYGVPRIAKLGSNENPLGPSPAVRRAFADIAELLRLYPDPQGRALREAIAARTGVPADRIILGNG 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  90 SDQVIEFAIHAKLNSKNAFLQAGVTFAMYEIYAKQCGAKCYK---TQSITHNLDEfkkLYETHKDEIKLIFLCLPNNPLG 166
Cdd:PRK05166  97 SEDLIAVICRAVLRPGDRVVTLYPSFPLHEDYPTMMGARVERvtvTPDLGFDLDA---LCAAVARAPRMLMFSNPSNPVG 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 167 ECLDASEVTKFIKGVEEDCLVVIDAAYNEFASFKDSKKHLepcELIKEFD-NVLYLGTFSKLYGLGGLRIGYGIA-DASI 244
Cdd:PRK05166 174 SWLTADQLARVLDATPPETLIVVDEAYAEYAAGDDYPSAL---TLLKARGlPWIVLRTFSKAYGLAGLRVGYGLVsDPEL 250

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 245 ISAFYKLRAPFNVSNLALKAAVAAMDDDEFTEKTLENNFSQMELYKEFAKKHNIKIIDSYTNFItyFFDEK-NSTDLSEK 323
Cdd:PRK05166 251 VGLLDRVRTPFNVNGAAQAAALAALDDEEHLAKGVALALAERERLKKELAEMGYRIAPSRANFL--FFDARrPASAVAEA 328

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|.
gi 489011712 324 LLKKGIIIRNLKSYGLNA-IRITIGTSYENERFFTEFDKIL 363
Cdd:PRK05166 329 LLRQGVIVKPWKQPGFETfIRVSIGSPEENDHFVAALDKVL 369
AAT_like cd00609
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ...
 32-354 5.78e-60

Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.


Pssm-ID: 99734 [Multi-domain]  Cd Length: 350  Bit Score: 196.79  E-value: 5.78e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  32 IKLASNENPFGTPPKAIECLRQNANKA---HLYPDDSMIELKSTLAQKYKVQN------ENIIIGAGSDQVIEFAIHAKL 102
Cdd:cd00609    1 IDLSIGEPDFPPPPEVLEALAAAALRAgllGYYPDPGLPELREAIAEWLGRRGgvdvppEEIVVTNGAQEALSLLLRALL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 103 NSKNAFLQAGVTFAMYEIYAKQCGAKCYKTQSITHN--LDEFKKLYETHKDEIKLIFLCLPNNPLGECLDASEVTKFIKG 180
Cdd:cd00609   81 NPGDEVLVPDPTYPGYEAAARLAGAEVVPVPLDEEGgfLLDLELLEAAKTPKTKLLYLNNPNNPTGAVLSEEELEELAEL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 181 VEE-DCLVVIDAAYNEFAsfkDSKKHLEPCELIKEFDNVLYLGTFSKLYGLGGLRIGYGIADASIISAFYKLRAPF---N 256
Cdd:cd00609  161 AKKhGILIISDEAYAELV---YDGEPPPALALLDAYERVIVLRSFSKTFGLPGLRIGYLIAPPEELLERLKKLLPYttsG 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 257 VSNLALKAAVAAMDD-DEFTEKTLENNFSQMELYKEFAKKHN--IKIIDSYTNFITYFFDEKNSTDLSEKLLKK-GIIIR 332
Cdd:cd00609  238 PSTLSQAAAAAALDDgEEHLEELRERYRRRRDALLEALKELGplVVVKPSGGFFLWLDLPEGDDEEFLERLLLEaGVVVR 317

                        330       340
                 ....*....|....*....|....*
gi 489011712 333 NLKSYGL---NAIRITIGTSYENER 354
Cdd:cd00609  318 PGSAFGEggeGFVRLSFATPEEELE 342
PLN03026 PLN03026
histidinol-phosphate aminotransferase; Provisional
 10-355 2.68e-59

histidinol-phosphate aminotransferase; Provisional


Pssm-ID: 178597  Cd Length: 380  Bit Score: 196.07  E-value: 2.68e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  10 LSNYEPGKDIEVIAKEYGVK--EVIKLASNENPFGTPPKAIECLRqNANKAHLYPDDSMIELKSTLAQKYKVQNENIIIG 87
Cdd:PLN03026  31 LAPYQPILPFEVLSAQLGRKpeDIVKLDANENPYGPPPEVLEALG-NMKFPYVYPDPESRRLRAALAEDSGLESENILVG 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  88 AGSDQVIEFAIHAKLNSKNAFLQAGVTFAMYEIYAKQCGAKCYK---TQSITHNLDEFKKLYETHKDeiKLIFLCLPNNP 164
Cdd:PLN03026 110 CGADELIDLLMRCVLDPGDKIIDCPPTFGMYVFDAAVNGAEVIKvprTPDFSLDVPRIVEAVETHKP--KLLFLTSPNNP 187

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 165 LGECLDASEVTKFIkgvEEDCLVVIDAAYNEFASFKDSKKhlepceLIKEFDNVLYLGTFSKLYGLGGLRIGYGIADASI 244
Cdd:PLN03026 188 DGSIISDDDLLKIL---ELPILVVLDEAYIEFSTQESRMK------WVKKYDNLIVLRTFSKRAGLAGLRVGYGAFPLSI 258

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 245 ISAFYKLRAPFNVSNLALKAAVAAMDDDEFTEKTLENNFSQME-LYKEFAKKHNIKIIDSYTNFItyFFDEKNSTD---L 320
Cdd:PLN03026 259 IEYLWRAKQPYNVSVAAEVAACAALSNPKYLEDVKNALVEERErLFGLLKEVPFLEPYPSDANFI--LCRVTSGRDakkL 336

                        330       340       350
                 ....*....|....*....|....*....|....*.
gi 489011712 321 SEKLLKKGIIIRNLKSYGLNA-IRITIGTSYENERF 355
Cdd:PLN03026 337 KEDLAKMGVMVRHYNSKELKGyIRVSVGKPEHTDAL 372
PRK03321 PRK03321
putative aminotransferase; Provisional
 13-355 8.05e-57

putative aminotransferase; Provisional


Pssm-ID: 179559  Cd Length: 352  Bit Score: 188.64  E-value: 8.05e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  13 YEPGKDieviakeygVKEVIKLASNENPFGTPPKAIECLRQNANKAHLYPDDSMIELKSTLAQKYKVQNENIIIGAGSDQ 92
Cdd:PRK03321  15 YVPGKT---------VPGAIKLSSNETPFGPLPSVRAAIARAAAGVNRYPDMGAVELRAALAEHLGVPPEHVAVGCGSVA 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  93 VIEFAIHAKLNSKNAFLQAGVTFAMYEIYAKQCGAKCYK---TQSITHNLDefkKLYETHKDEIKLIFLCLPNNPLGECL 169
Cdd:PRK03321  86 LCQQLVQATAGPGDEVIFAWRSFEAYPILVQVAGATPVQvplTPDHTHDLD---AMAAAITDRTRLIFVCNPNNPTGTVV 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 170 DASEVTKFIKGVEEDCLVVIDAAYNEFASFKDSKKHLEpceLIKEFDNVLYLGTFSKLYGLGGLRIGYGIADASIISAFY 249
Cdd:PRK03321 163 TPAELARFLDAVPADVLVVLDEAYVEYVRDDDVPDGLE---LVRDHPNVVVLRTFSKAYGLAGLRVGYAVGHPEVIAALR 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 250 KLRAPFNVSNLALKAAVAAMD-DDEFTEKTlENNFSQMELYKEFAKKHNIKIIDSYTNFITYFFDEKnSTDLSEKLLKKG 328
Cdd:PRK03321 240 KVAVPFSVNSLAQAAAIASLAaEDELLERV-DAVVAERDRVRAALRAAGWTVPPSQANFVWLPLGER-TADFAAAAAEAG 317

                        330       340
                 ....*....|....*....|....*..
gi 489011712 329 IIIRnlkSYGLNAIRITIGTSYENERF 355
Cdd:PRK03321 318 VVVR---PFAGEGVRVTIGAPEENDAF 341
Aminotran_1_2 pfam00155
Aminotransferase class I and II;
29-355 1.52e-51

Aminotransferase class I and II;


Pssm-ID: 395103 [Multi-domain]  Cd Length: 351  Bit Score: 175.19  E-value: 1.52e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712   29 KEVIKLASNENPFGTPPKAIECLRQNA--NKAHLYPD-DSMIELKSTLAQKYKVQNE-------NIIIGAGSDQVIEFAI 98
Cdd:pfam00155   1 TDKINLGSNEYLGDTLPAVAKAEKDALagGTRNLYGPtDGHPELREALAKFLGRSPVlkldreaAVVFGSGAGANIEALI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712   99 HAKLNSKNAFLQAGVTFAMYEIYAKQCGAKCYK---TQSITHNLDeFKKLYETHKDEIKLIFLCLPNNPLGECLDASEVT 175
Cdd:pfam00155  81 FLLANPGDAILVPAPTYASYIRIARLAGGEVVRyplYDSNDFHLD-FDALEAALKEKPKVVLHTSPHNPTGTVATLEELE 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  176 KFIKGVEE-DCLVVIDAAYNEFASfkDSKKHLEPCELIKEFDNVLYLGTFSKLYGLGGLRIGYGIADASIISAFYKLRAP 254
Cdd:pfam00155 160 KLLDLAKEhNILLLVDEAYAGFVF--GSPDAVATRALLAEGPNLLVVGSFSKAFGLAGWRVGYILGNAAVISQLRKLARP 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  255 FNVSNLALKAAVAAMDDDEFTEKTLENN-----FSQMELYKEFAKKhNIKIIDSYTNFITY-FFDEKNSTDLSEKLLK-K 327
Cdd:pfam00155 238 FYSSTHLQAAAAAALSDPLLVASELEEMrqrikERRDYLRDGLQAA-GLSVLPSQAGFFLLtGLDPETAKELAQVLLEeV 316

                         330       340       350
                  ....*....|....*....|....*....|.
gi 489011712  328 GIIIRNLKSYGL-NAIRITI--GTSYENERF 355
Cdd:pfam00155 317 GVYVTPGSSPGVpGWLRITVagGTEEELEEL 347
PRK02610 PRK02610
histidinol-phosphate transaminase;
33-364 1.53e-41

histidinol-phosphate transaminase;


Pssm-ID: 235053  Cd Length: 374  Bit Score: 149.09  E-value: 1.53e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  33 KLASNENPFGTPPKAIECLR---QNANKAHLYPDDSMIELKSTLAQ--------KYKVQNENIIIGAGSDQVIEFAIHAK 101
Cdd:PRK02610  32 RLDTNEFPYDLPPDLKQKLAwlyQQGIESNRYPDGGHEALKQAIAEyvnesaagSSQITPANISVGNGSDELIRSLLIAT 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 102 -LNSKNAFLQAGVTFAMYEIYAKQCGAKcykTQSITHNLDEFK--------KLYETHKDEIKLIFLCLPNNPLGECLDAS 172
Cdd:PRK02610 112 cLGGEGSILVAEPTFSMYGILAQTLGIP---VVRVGRDPETFEidlaaaqsAIEQTQNPPVRVVFVVHPNSPTGNPLTAA 188

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 173 EVTkFIKGVEEDCLVVIDAAYNEFasfkdSKKHLEPceLIKEFDNVLYLGTFSKLYGLGGLRIGYGIADASIISAFYKLR 252
Cdd:PRK02610 189 ELE-WLRSLPEDILVVIDEAYFEF-----SQTTLVG--ELAQHPNWVILRTFSKAFRLAAHRVGYAIGHPELIAVLEKVR 260

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 253 APFNVSNLALKAAVAAMDDDEFTEKTLENNFSQME-LYKEFAKKHNIKIIDSYTNFItyFFDEKNSTDLS---EKLLKKG 328
Cdd:PRK02610 261 LPYNLPSFSQLAAQLALEHRQELLAAIPEILQERDrLYQALQELPQLRVWPSAANFL--YLRLSQDAALAalhQALKAQG 338

                        330       340       350
                 ....*....|....*....|....*....|....*.
gi 489011712 329 IIIRNLkSYGLnaiRITIGTSYENERFFTEFDKILR 364
Cdd:PRK02610 339 TLVRHT-GGGL---RITIGTPEENQRTLERLQAALT 370
PRK08153 PRK08153
pyridoxal phosphate-dependent aminotransferase;
20-364 3.77e-36

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 181255  Cd Length: 369  Bit Score: 134.74  E-value: 3.77e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  20 EVIAKEYGVKEVIKLASNENPFGTPPKAIECLRQNANKAHLYPDDSMIELKSTLAQKYKVQNENIIIGAGSD-------- 91
Cdd:PRK08153  23 ETLERQRGRPFRARIGANESGFGPSPSVIAAMREAAAEIWKYGDPENHDLRHALAAHHGVAPENIMVGEGIDgllglivr 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  92 QVIEfAIHAKLNSKNAFlqagVTFAmYEIYAKqcGAKCYKTQSITHNLDEFKKLYETHKDEIKLIFLCLPNNPLGECLDA 171
Cdd:PRK08153 103 LYVE-PGDPVVTSLGAY----PTFN-YHVAGF--GGRLVTVPYRDDREDLDALLDAARRENAPLVYLANPDNPMGSWHPA 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 172 SEVTKFIKGVEEDCLVVIDAAYNEFAsfkdskkhlePCELIKEFD----NVLYLGTFSKLYGLGGLRIGYGIADASIISA 247
Cdd:PRK08153 175 ADIVAFIEALPETTLLVLDEAYCETA----------PAGAAPPIDtddpNVIRMRTFSKAYGLAGARVGYAIGAPGTIKA 244

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 248 FYKLRAPFNVSNLALKAAVAAMDDDEFTEKTLENNFSQMELYKEFAKKHNIKIIDSYTNFITY--FFDEKNSTDLSEKLL 325
Cdd:PRK08153 245 FDKVRNHFGMNRIAQAAALAALKDQAYLAEVVGKIAAARDRIAAIARANGLTPLPSATNFVAIdcGRDGAFARAVLDGLI 324

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|
gi 489011712 326 KKGIIIRNLKSYGLN-AIRITIGTSYENERFFTEFDKILR 364
Cdd:PRK08153 325 ARDIFVRMPGVAPLDrCIRVSCGPDEELDLFAEALPEALE 364
AspB COG0436
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; ...
 29-273 5.95e-26

Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis


Pssm-ID: 440205 [Multi-domain]  Cd Length: 387  Bit Score: 107.14  E-value: 5.95e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  29 KEVIKLASNENPFGTPPKAIECLRQNANK-AHLYPDDS-MIELKSTLAQKYKVQN------ENIIIGAGSDQVIEFAIHA 100
Cdd:COG0436   30 EDVIDLGIGEPDFPTPDHIREAAIEALDDgVTGYTPSAgIPELREAIAAYYKRRYgvdldpDEILVTNGAKEALALALLA 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 101 klnsknaFLQAG--V-----TFAMYEIYAKQCGAKC--YKTQSITHNLDEFKKLYETHKDEIKLIFLCLPNNPLGECLDA 171
Cdd:COG0436  110 -------LLNPGdeVlvpdpGYPSYRAAVRLAGGKPvpVPLDEENGFLPDPEALEAAITPRTKAIVLNSPNNPTGAVYSR 182

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 172 SEVTKFIK-GVEEDCLVVIDAAYNEFAsFkDSKKHLEPCELIKEFDNVLYLGTFSKLYGLGGLRIGYGIADASIISAFYK 250
Cdd:COG0436  183 EELEALAElAREHDLLVISDEIYEELV-Y-DGAEHVSILSLPGLKDRTIVINSFSKSYAMTGWRIGYAVGPPELIAALLK 260

                        250       260
                 ....*....|....*....|....*
gi 489011712 251 LRA--PFNVSNLALKAAVAAMDDDE 273
Cdd:COG0436  261 LQSnlTSCAPTPAQYAAAAALEGPQ 285
PRK03317 PRK03317
histidinol-phosphate aminotransferase; Provisional
 32-364 1.23e-22

histidinol-phosphate aminotransferase; Provisional


Pssm-ID: 235115  Cd Length: 368  Bit Score: 97.63  E-value: 1.23e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  32 IKLASNENPFGTPPKAIECL----RQNANKAHLYPDDSMIELKSTLAQKYKVQN------ENIIIGAGSDQVIEfaihak 101
Cdd:PRK03317  29 VRLNTNENPYPPSPALVADIaeavAEAAAGLNRYPDRDAVALRADLAAYLTAQTgvgltvENVWAANGSNEILQ------ 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 102 lnsknAFLQA---------GV--TFAMYEIYAKQCG---AKCYKTQSITHNLDEFKKLYETHKDEIklIFLCLPNNPLGE 167
Cdd:PRK03317 103 -----QLLQAfggpgrtalGFvpSYSMHPIIARGTHtewVEGPRAADFTLDVDAAVAAIAEHRPDV--VFLTSPNNPTGT 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 168 CLDASEVTKFIKGVEedCLVVIDAAYNEFAsfkdskKHLEP--CELIKEFDNVLYLGTFSKLYGLGGLRIGYGIADASII 245
Cdd:PRK03317 176 ALPLDDVEAILDAAP--GIVVVDEAYAEFR------RSGTPsaLTLLPEYPRLVVSRTMSKAFAFAGGRLGYLAAAPAVV 247

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 246 SAFYKLRAPFNVSNLALKAAVAAMDDDEFTEKTLENNFSQMELYKEFAKKHNIKIIDSYTNFItyFFDE-KNSTDLSEKL 324
Cdd:PRK03317 248 DALRLVRLPYHLSAVTQAAARAALRHADELLASVAALRAERDRVVAWLRELGLRVAPSDANFV--LFGRfADRHAVWQGL 325

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|
gi 489011712 325 LKKGIIIRNLKSYGLnaIRITIGTSYENERFFTEFDKILR 364
Cdd:PRK03317 326 LDRGVLIRDVGIPGW--LRVTIGTPEENDAFLAALAEVLA 363
PRK09105 PRK09105
pyridoxal phosphate-dependent aminotransferase;
23-364 2.40e-22

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 181651  Cd Length: 370  Bit Score: 96.65  E-value: 2.40e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  23 AKEYGVKEVIKLASNENPFGTPPKAIECLRQNANKAHLYPDDSMIELKSTLAQKYKVQNENIIIGAGSDQVIEFAIHAKL 102
Cdd:PRK09105  37 AAPPAAEGAVFLNANECPLGPSPAARDAAARSAALSGRYDLELEDDLRTLFAAQEGLPADHVMAYAGSSEPLNYAVLAFT 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 103 NSKNAFLQAGVTFAMYEIYAKQCGAKCYKTqsithnldefkKLYETHKDEIK----------LIFLCLPNNPLGECLDAS 172
Cdd:PRK09105 117 SPTAGLVTADPTYEAGWRAADAQGAPVAKV-----------PLRADGAHDVKamlaadpnagLIYICNPNNPTGTVTPRA 185

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 173 EVTKFIKGVEEDCLVVIDAAYNEFASfkdskkhlEP--CELIKEFDNVLYLGTFSKLYGLGGLRIGYGIADASIISafyK 250
Cdd:PRK09105 186 DIEWLLANKPAGSVLLVDEAYIHFSD--------APsvVDLVAQRKDLIVLRTFSKLYGMAGMRLGLAAARPDLLA---K 254

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 251 LrAPFNVSNLALKAAVAAM----DDDEFTEKTLENNFSQMELYkEFAKKHNIKIIDSYTNFitYFFD-EKNSTDLSEKLL 325
Cdd:PRK09105 255 L-ARFGHNPLPVPAAAAGLaslrDPKLVPQRRAENAAVREDTI-AWLKKKGYKCTPSQANC--FMVDvKRPAKAVADAMA 330

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|
gi 489011712 326 KKGIII-RNLKSYGlNAIRITIGTSYENERFFTEFDKILR 364
Cdd:PRK09105 331 KQGVFIgRSWPIWP-NWVRVTVGSEEEMAAFRSAFAKVMR 369
PRK06225 PRK06225
pyridoxal phosphate-dependent aminotransferase;
29-363 2.99e-20

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 235749 [Multi-domain]  Cd Length: 380  Bit Score: 90.97  E-value: 2.99e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  29 KEVIKLASNENPFGTPPKAIECLRQNANKAHL--Y-PDDSMIELKSTLAQKYKVQNENIIIGAGSDQVIEFAIHAKLNSK 105
Cdd:PRK06225  28 KEMIWMGQNTNHLGPHEEVREAMIRCIEEGEYckYpPPEGFPELRELILKDLGLDDDEALITAGATESLYLVMRAFLSPG 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 106 NAFL--------------QAGVTFAMYEIYAKQCGakcYK--TQSITHNLDEfkklyethkdEIKLIFLCLPNNPLGECL 169
Cdd:PRK06225 108 DNAVtpdpgyliidnfasRFGAEVIEVPIYSEECN---YKltPELVKENMDE----------NTRLIYLIDPLNPLGSSY 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 170 DASEVTKFIK-GVEEDCLVVIDAAYNEFAsfkdsKKHLEPCELIKEFDNVLYlgTFSKLYGLGGLRIGYGIADASIISAF 248
Cdd:PRK06225 175 TEEEIKEFAEiARDNDAFLLHDCTYRDFA-----REHTLAAEYAPEHTVTSY--SFSKIFGMAGLRIGAVVATPDLIEVV 247

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 249 YKLR-APFNVSNLALKAAVAAMD-DDEFTEKTLENNFSQMELYKEFAKKHN---IKIIDSYTNFITYFFDEK--NSTDLS 321
Cdd:PRK06225 248 KSIViNDLGTNVIAQEAAIAGLKvKDEWIDRIRRTTFKNQKLIKEAVDEIEgvfLPVYPSHGNMMVIDISEAgiDPEDLV 327

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*..
gi 489011712 322 EKLLKKGIIIR----NLKSYGLNAIRITIGTSYEN-ERFFTEFDKIL 363
Cdd:PRK06225 328 EYLLERKIFVRqgtyTSKRFGDRYIRVSFSIPREQvEVFCEEFPDVV 374
PRK08354 PRK08354
putative aminotransferase; Provisional
 77-354 1.26e-19

putative aminotransferase; Provisional


Pssm-ID: 169399  Cd Length: 311  Bit Score: 88.25  E-value: 1.26e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  77 YKVQNENIIIGAGSDQVIEFAIHAKLNSKNAFLQAGvTFAMYEIYAKQCGAKcyktqsITHNLDEFKKLYETHKDEIkLI 156
Cdd:PRK08354  50 SKLFGEPIVITAGITEALYLIGILALRDRKVIIPRH-TYGEYERVARFFAAR------IIKGPNDPEKLEELVERNS-VV 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 157 FLCLPNNPLGECLDASEVTKFIKGVE-EDCLVVIDAAYNEFASFKDSKkhlepcelikEFDNVLYLGTFSKLYGLGGLRI 235
Cdd:PRK08354 122 FFCNPNNPDGKFYNFKELKPLLDAVEdRNALLILDEAFIDFVKKPESP----------EGENIIKLRTFTKSYGLPGIRV 191

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 236 GYGIadaSIISAFYKLRAPFNVSNLalkaAVAamdddeFTEKTLENNFSQ----MELYKEfaKKHNIK---IIDSYTNFi 308
Cdd:PRK08354 192 GYVK---GFEEAFRSVRMPWSIGST----GYA------FLEFLIEDDFEHlrktMPLIWR--EKERFEkalYVKSDANF- 255

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 489011712 309 tYFFDEKNSTDLSEKLLKKGIIIRNLKSYGL-NAIRITIGTSYENER 354
Cdd:PRK08354 256 -FIKDVGDAEKFVEFLKRNGILVRDCTSFGLpGYIRFSVRDREENEK 301
PRK06425 PRK06425
histidinol-phosphate aminotransferase; Validated
 16-363 3.78e-16

histidinol-phosphate aminotransferase; Validated


Pssm-ID: 102370  Cd Length: 332  Bit Score: 78.36  E-value: 3.78e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  16 GKDIEVIAKEYGvkEVIKLASNENPFgtppkaieclrQNANKAHLYPDDSMIELKSTLAQKYKVQNENIIIGAGSDQVIe 95
Cdd:PRK06425   5 GGDVYEASSKYG--RIIDFSANINDF-----------MDIGDISIYPEISYTDIEDQIKIYTQGLKIKVLIGPGLTHFI- 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  96 FAIHAKLNSKNAFLqAGVTFAMYEIYAKQCGAKcykTQSITHNLDEFKKLYETHKDEiKLIFLCLPNNPLGECLDASEVT 175
Cdd:PRK06425  71 YRLLSYINVGNIII-VEPNFNEYKGYAFTHGIR---ISALPFNLINNNPEILNNYNF-DLIFIVSPDNPLGNLISRDSLL 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 176 KfikgVEEDC-----LVVIDAAYNEFAsfkdsKKHLEPCELI-KEFDNVLYLGTFSKLYGLGGLRIGYGIADASIISAFY 249
Cdd:PRK06425 146 T----ISEICrkkgaLLFIDEAFIDFV-----PNRAEEDVLLnRSYGNVIIGRSLTKILGIPSLRIGYIATDDYNMKISR 216

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 250 KLRAPFNVSNLALKaAVAAMDDDEFTEKTLENNFSQMELYKEFAKKHNIKII-DSYTNFITyfFDEKNSTDLSEKLLKKG 328
Cdd:PRK06425 217 KITEPWSVCDPAID-FIRSIDLDYVAKHSLDIMENERSYLINNLEAMGFRAAgDPSANFIT--FMIPDAHDFYSYLLKNG 293

                        330       340       350
                 ....*....|....*....|....*....|....*...
gi 489011712 329 IIIRNLKSY---GLNAIRITIGTSYENERFFTEFDKIL 363
Cdd:PRK06425 294 ILVRLLDDYeclGEQYIRIAIRRRSFNIKLVNALRNFL 331
PRK05764 PRK05764
aspartate aminotransferase; Provisional
 31-273 2.55e-15

aspartate aminotransferase; Provisional


Pssm-ID: 235596  Cd Length: 393  Bit Score: 76.32  E-value: 2.55e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  31 VIKLASNENPFGTPPK----AIECLRQNANKahlY-PDDSMIELKSTLAQKYKVQN------ENIIIGAGSDQVIefaih 99
Cdd:PRK05764  33 VISLGAGEPDFDTPEHikeaAIEALDDGKTK---YtPAAGIPELREAIAAKLKRDNgldydpSQVIVTTGAKQAL----- 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 100 akLNSKNAFLQAG----------VTfamYEIYAKQCGAKcyktqSITHNLDE---FKKLYETHKDEI----KLIFLCLPN 162
Cdd:PRK05764 105 --YNAFMALLDPGdeviipapywVS---YPEMVKLAGGV-----PVFVPTGEengFKLTVEQLEAAItpktKALILNSPS 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 163 NPLGECLDASEVTKFIK-GVEEDCLVVIDAAYNEFASfkDSKKHLEPCELIKE-FDNVLYLGTFSKLYGLGGLRIGYGIA 240
Cdd:PRK05764 175 NPTGAVYSPEELEAIADvAVEHDIWVLSDEIYEKLVY--DGAEFTSIASLSPElRDRTITVNGFSKAYAMTGWRLGYAAG 252

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 489011712 241 DASIISAFYKLRAPF--NVSNLALKAAVAAMDDDE 273
Cdd:PRK05764 253 PKELIKAMSKLQSHStsNPTSIAQYAAVAALNGPQ 287
PRK08361 PRK08361
aspartate aminotransferase; Provisional
 20-352 3.79e-15

aspartate aminotransferase; Provisional


Pssm-ID: 236248 [Multi-domain]  Cd Length: 391  Bit Score: 76.07  E-value: 3.79e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  20 EVIAKEYGVKEVIKLASNENPFGTPpkaiECLRQNANKA------HLYPDDSMIELKSTLAQKYK------VQNENIIIG 87
Cdd:PRK08361  24 ELFERASKMENVISLGIGEPDFDTP----KNIKEAAKRAldegwtHYTPNAGIPELREAIAEYYKkfygvdVDVDNVIVT 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  88 AGSDQVIEFAIHAKLNSKNAFLQAGVTFAMYEIYAKQCGAKCYKTQSITHNldEFK----KLYETHKDEIKLIFLCLPNN 163
Cdd:PRK08361 100 AGAYEATYLAFESLLEEGDEVIIPDPAFVCYVEDAKIAEAKPIRIPLREEN--EFQpdpdELLELITKRTRMIVINYPNN 177

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 164 PLGECLDaSEVTKFIKGVEEDCLVVI--DAAYNEFAsFKDSKKHlepcELIK-EFDNVLYLGTFSKLYGLGGLRIGYGIA 240
Cdd:PRK08361 178 PTGATLD-KEVAKAIADIAEDYNIYIlsDEPYEHFL-YEGAKHY----PMIKyAPDNTILANSFSKTFAMTGWRLGFVIA 251

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 241 DASIISAFYKLRAPF--NVSNLALKAAVAAMDDDEfTEKTLEnnfsqmELYKEFAKKHniKIIDSYTNFITYF--FDEK- 315
Cdd:PRK08361 252 PEQVIKDMIKLHAYIigNVASFVQIAGIEALRSKE-SWKAVE------EMRKEYNERR--KLVLKRLKEMPHIkvFEPKg 322

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....
gi 489011712 316 -------------NSTDLSEKLLKK-GIIIRNLKSYGLNA---IRITIGTSYEN 352
Cdd:PRK08361 323 afyvfanidetgmSSEDFAEWLLEKaRVVVIPGTAFGKAGegyIRISYATSKEK 376
PRK05839 PRK05839
succinyldiaminopimelate transaminase;
30-284 3.61e-12

succinyldiaminopimelate transaminase;


Pssm-ID: 180281  Cd Length: 374  Bit Score: 67.02  E-value: 3.61e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  30 EVIKLASNENPFGTPPKAIECLRQNANKAHLYP----DDSMIELKSTLAQK-YKV--QNENIIIGAGSDQVI----EFAI 98
Cdd:PRK05839  25 KGLDLTIGEPQFETPKFIQDALKNNAHLLNKYPksagEESLREAQRGFFKRrFKIelKENELIPTFGTREVLfnfpQFVL 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  99 HAKLNSKNAFlqagvTFAMYEIYakQCGAKCYKTQSITHNLDE---FK-KLYETHKDEIKLIFLCLPNNPLGECLDASEV 174
Cdd:PRK05839 105 FDKQNPTIAY-----PNPFYQIY--EGAAIASRAKVLLMPLTKendFTpSLNEKELQEVDLVILNSPNNPTGRTLSLEEL 177

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 175 TKFIK-GVEEDCLVVIDAAYNEFASFKDSKKHLEPCELI--KEFDNVLYLGTFSKLYGLGGLRIGYGIADASIISAFYKL 251
Cdd:PRK05839 178 IEWVKlALKHDFILINDECYSEIYENTPPPSLLEASILVgnESFKNVLVINSISKRSSAPGLRSGFIAGDASILKKYKAY 257

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 489011712 252 RAPFN-VSNLAL-KAAVAAMDDDE---FTEKTLENNFS 284
Cdd:PRK05839 258 RTYLGcASPLPLqKAAAVAWLDDEhaeFFRNIYAKNLK 295
PRK07682 PRK07682
aminotransferase;
68-273 3.01e-11

aminotransferase;


Pssm-ID: 181082 [Multi-domain]  Cd Length: 378  Bit Score: 63.99  E-value: 3.01e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  68 ELKSTLAQKYKVQ---NENIIIGAGSDQVIEFAIHAKLNSKNAFLQAGVTFAMYEIYAKQCGAKCYKTQsiTHNLDEFK- 143
Cdd:PRK07682  65 EIAKYLKKRFAVSydpNDEIIVTVGASQALDVAMRAIINPGDEVLIVEPSFVSYAPLVTLAGGVPVPVA--TTLENEFKv 142

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 144 ---KLYETHKDEIKLIFLCLPNNPLGECLDASEVTKFIKGVEEDCLVVI----------DAAYNEFASFKDSKKHlepce 210
Cdd:PRK07682 143 qpaQIEAAITAKTKAILLCSPNNPTGAVLNKSELEEIAVIVEKHDLIVLsdeiyaeltyDEAYTSFASIKGMRER----- 217

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489011712 211 likefdNVLYLGtFSKLYGLGGLRIGYGIADASIISAFYKLR------APFNVSNLALKAAVAAMDDDE 273
Cdd:PRK07682 218 ------TILISG-FSKGFAMTGWRLGFIAAPVYFSEAMLKIHqysmmcAPTMAQFAALEALRAGNDDVI 279
ARO8 COG1167
DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain ...
 51-353 5.10e-11

DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain [Transcription, Amino acid transport and metabolism]; DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain is part of the Pathway/BioSystem: Lysine biosynthesis


Pssm-ID: 440781 [Multi-domain]  Cd Length: 471  Bit Score: 63.69  E-value: 5.10e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  51 LRQNANKAHLYPDDS-MIELKSTLAQKYK-----VQNENIIIGAGSDQVIEFAIHAklnsknaFLQAGVTFAM-----YE 119
Cdd:COG1167  134 LRRLPPALLGYGDPQgLPELREAIARYLArrgvpASPDQILITSGAQQALDLALRA-------LLRPGDTVAVesptyPG 206

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 120 IY--AKQCGAKcykTQSI-TH----NLDEFKKLYETHKdeIKLIFLClPN--NPLGECLDASEVTKFIKGVEE-DCLVVI 189
Cdd:COG1167  207 ALaaLRAAGLR---LVPVpVDedglDLDALEAALRRHR--PRAVYVT-PShqNPTGATMSLERRRALLELARRhGVPIIE 280

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 190 DAAYNEFAsfkDSKKHLEPcelIKEFD---NVLYLGTFSKLYGlGGLRIGYGIADASIISAFYKLRAPFNVSNLALKAAV 266
Cdd:COG1167  281 DDYDSELR---YDGRPPPP---LAALDapgRVIYIGSFSKTLA-PGLRLGYLVAPGRLIERLARLKRATDLGTSPLTQLA 353

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 267 AA--MDDDEFtEKTLEnnfsqmELYKEFAKKHN--IKIIDSYTNFIT--------YFF-----DEKNSTDLSEKLLKKGI 329
Cdd:COG1167  354 LAefLESGHY-DRHLR------RLRREYRARRDllLAALARHLPDGLrvtgppggLHLwlelpEGVDAEALAAAALARGI 426

                        330       340
                 ....*....|....*....|....*....
gi 489011712 330 IIRNLKSYGL-----NAIRITIGTSYENE 353
Cdd:COG1167  427 LVAPGSAFSAdgpprNGLRLGFGAPSEEE 455
PRK09276 PRK09276
LL-diaminopimelate aminotransferase; Provisional
 1-291 7.85e-09

LL-diaminopimelate aminotransferase; Provisional


Pssm-ID: 181749  Cd Length: 385  Bit Score: 56.84  E-value: 7.85e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712   1 MKFNEFLNHLSNY-----EPGKDiEVIAKeyGVkEVIKLASNENPFGTPPKAIECLRQNANKA--HLYPDDS-MIELKST 72
Cdd:PRK09276   2 MKLADRIKNLPPYlfaeiDKKKA-EKIAR--GV-DVISLGIGDPDLPTPDHIIEAMCKAVEDPenHQYPSYEgMLEFRKA 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  73 LAQKYK----VQ---NENIIIGAGSDQVIEfaiHAKLnsknAFLQAG-VT------FAMYEIYAKQCGAKCYKTQSITHN 138
Cdd:PRK09276  78 VADWYKrrfgVEldpETEVISLIGSKEGIA---HIPL----AFVNPGdVVlvpdpgYPVYKIGTIFAGGEPYFMPLKEEN 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 139 --LDEFKKLYETHKDEIKLIFLCLPNNPLGECLDAS---EVTKFIKgvEEDCLVVIDAAYNEFASfkDSKKHLEPCELIK 213
Cdd:PRK09276 151 gfLPDLDAIPEDVAKKAKLMFINYPNNPTGAVADLEffeEVVDFAK--KYDIIVCHDAAYSEIAY--DGYKPPSFLEVPG 226

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 214 EFDNVLYLGTFSKLYGLGGLRIGYGIADASIISAFYKLRApfNVSNLAL----KAAVAAMD-DDEFTEKTlennfsqMEL 288
Cdd:PRK09276 227 AKDVGIEFHSLSKTYNMTGWRIGFAVGNADLIAGLGKVKS--NVDSGVFqaiqEAGIAALNgPQEVVEEL-------RKI 297


                 ...
gi 489011712 289 YKE 291
Cdd:PRK09276 298 YQE 300
PRK07681 PRK07681
LL-diaminopimelate aminotransferase;
115-291 8.62e-09

LL-diaminopimelate aminotransferase;


Pssm-ID: 181081  Cd Length: 399  Bit Score: 56.74  E-value: 8.62e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 115 FAMYEIYAKQCGAKCY--KTQSITHNLDEFKKLYETHKDEIKLIFLCLPNNPLGECLDAS---EVTKFIKgvEEDCLVVI 189
Cdd:PRK07681 127 YTAYETGIQMAGATSYymPLKKENDFLPDLELIPEEIADKAKMMILNFPGNPVPAMAHEDffkEVIAFAK--KHNIIVVH 204

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 190 DAAYNEFasFKDSKKHLEPCELIKEFDNVLYLGTFSKLYGLGGLRIGYGIADASIISAF--YKLRAPFNVSNLALKAAVA 267
Cdd:PRK07681 205 DFAYAEF--YFDGNKPISFLSVPGAKEVGVEINSLSKSYSLAGSRIGYMIGNEEIVRALtqFKSNTDYGVFLPIQKAACA 282

                        170       180
                 ....*....|....*....|....*
gi 489011712 268 AMDD-DEFTEKtlennfsQMELYKE 291
Cdd:PRK07681 283 ALRNgAAFCEK-------NRGIYQE 300
PRK08363 PRK08363
alanine aminotransferase; Validated
 43-237 9.65e-09

alanine aminotransferase; Validated


Pssm-ID: 181402  Cd Length: 398  Bit Score: 56.35  E-value: 9.65e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  43 TPPKAI-ECLRQNANKAHLY--PDDSMIELKSTLAQKYKVQN------ENIIIGAGSDQVIEFAIHAKLNSKNAFLQAGV 113
Cdd:PRK08363  46 QPPEHMkEAYCRAIKEGHNYygPSEGLPELREAIVKREKRKNgvditpDDVRVTAAVTEALQLIFGALLDPGDEILIPGP 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 114 TFAMYEIYAKQCGAKCYKTQSITHN-----LDEFKKLYEthkDEIKLIFLCLPNNPLGECLDASEVTKFIKGVEEDCLVV 188
Cdd:PRK08363 126 SYPPYTGLVKFYGGVPVEYRTIEEEgwqpdIDDIRKKIT---EKTKAIAVINPNNPTGALYEKKTLKEILDIAGEHDLPV 202

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 489011712 189 IDAAYNEFASFKDskKHLEPCELIKEfDNVLYLGTFSKLYGLGGLRIGY 237
Cdd:PRK08363 203 ISDEIYDLMTYEG--KHVSPGSLTKD-VPVIVMNGLSKVYFATGWRLGY 248
PRK06348 PRK06348
pyridoxal phosphate-dependent aminotransferase;
136-355 3.17e-08

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 180537  Cd Length: 384  Bit Score: 54.73  E-value: 3.17e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 136 THNLDEF----KKLYETHKDEIKLIFLCLPNNPLGECLDASEVTKFIK-GVEEDCLVVIDAAYNEFaSFKDSKKHLEPCE 210
Cdd:PRK06348 142 TYEEDGFqinvKKLEALITSKTKAIILNSPNNPTGAVFSKETLEEIAKiAIEYDLFIISDEVYDGF-SFYEDFVPMATLA 220

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 211 LIKEfdNVLYLGTFSKLYGLGGLRIGYGIADASIISAFYKLRA--PFNVSNLALKAAVAAMDD-DEFTEKTLENNFSQME 287
Cdd:PRK06348 221 GMPE--RTITFGSFSKDFAMTGWRIGYVIAPDYIIETAKIINEgiCFSAPTISQRAAIYALKHrDTIVPLIKEEFQKRLE 298

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489011712 288 -LYKEFAKKHNIKIID---SYTNFITYFFDEKNSTDLSEKLLKKGIII----RNLKSYGLNAIRI--TIGTSYENERF 355
Cdd:PRK06348 299 yAYKRIESIPNLSLHPpkgSIYAFINIKKTGLSSVEFCEKLLKEAHVLvipgKAFGESGEGYIRLacTVGIEVLEEAF 376
PRK06107 PRK06107
aspartate transaminase;
29-273 2.57e-07

aspartate transaminase;


Pssm-ID: 180403  Cd Length: 402  Bit Score: 52.04  E-value: 2.57e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  29 KEVIKLASNENPFGTPPK----AIECLRQNANKahlY-PDDSMIELKSTLAQKYKVQN------ENIIIGAGSDQVIEFA 97
Cdd:PRK06107  33 RSIVDLTVGEPDFDTPDHikqaAVAAIERGETK---YtLVNGTPALRKAIIAKLERRNglhyadNEITVGGGAKQAIFLA 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  98 IHAKLNSKNAFLQAGVTFAMYEIYAKQCGAKCYKTQSITHnlDEFK----KLYETHKDEIKLIFLCLPNNPLGECLDASE 173
Cdd:PRK06107 110 LMATLEAGDEVIIPAPYWVSYPDMVLANDGTPVIVACPEE--QGFKltpeALEAAITPRTRWLILNAPSNPTGAVYSRAE 187

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 174 VTKFIKGVEE--DCLVVIDAAYNEFaSFKDSK-KHL---EPcELIkefDNVLYLGTFSKLYGLGGLRIGYGIADASIISA 247
Cdd:PRK06107 188 LRALADVLLRhpHVLVLTDDIYDHI-RFDDEPtPHLlaaAP-ELR---DRVLVTNGVSKTYAMTGWRIGYAAGPADLIAA 262

                        250       260
                 ....*....|....*....|....*...
gi 489011712 248 FYKLRAPF--NVSNLALKAAVAAMDDDE 273
Cdd:PRK06107 263 INKLQSQSssCPSSISQAAAAAALNGDQ 290
PRK07568 PRK07568
pyridoxal phosphate-dependent aminotransferase;
43-280 4.88e-07

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 181036  Cd Length: 397  Bit Score: 51.01  E-value: 4.88e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  43 TPPKAIECLRQNANKAHLY-PDDSMIELKSTLAQKYK-----VQNENIIIGAGSDQVIEFAIHAKLNSKNAFLQAGVTFA 116
Cdd:PRK07568  44 TPEVFFEAIKNYDEEVLAYsHSQGIPELREAFAKYYKkwgidVEPDEILITNGGSEAILFAMMAICDPGDEILVPEPFYA 123

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 117 MYEIYAKQCGAKC----------YKTQSIthnlDEFKKLYeTHKdeIKLIFLCLPNNPLGECLDASEVTKFIKGVEEDCL 186
Cdd:PRK07568 124 NYNGFATSAGVKIvpvttkieegFHLPSK----EEIEKLI-TPK--TKAILISNPGNPTGVVYTKEELEMLAEIAKKHDL 196

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 187 VVI-DAAYNEFASfkDSKKHLEPCELIKEFDNVLYLGTFSKLYGLGGLRIGYGIA-DASIISAFYKL-RAPFNVSNLALK 263
Cdd:PRK07568 197 FLIsDEVYREFVY--DGLKYTSALSLEGLEDRVIIIDSVSKRYSACGARIGCLISkNKELIAAAMKLcQARLSPPTLEQI 274

                        250
                 ....*....|....*...
gi 489011712 264 AAVAAMD-DDEFTEKTLE 280
Cdd:PRK07568 275 GAAALLDtPESYFDEVRE 292
PRK07366 PRK07366
LL-diaminopimelate aminotransferase;
223-280 3.86e-06

LL-diaminopimelate aminotransferase;


Pssm-ID: 180947  Cd Length: 388  Bit Score: 48.52  E-value: 3.86e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 489011712 223 TFSKLYGLGGLRIGYGIADASIISAFYKLRA--PFNVSNLALKAAVAAMD-DDEFTEKTLE 280
Cdd:PRK07366 236 TLSKSYNMGGFRIGFAIGNAQLIQALRQVKAvvDFNQYRGILNGAIAALTgPQATVQQTVQ 296
PRK07908 PRK07908
threonine-phosphate decarboxylase;
186-272 9.72e-06

threonine-phosphate decarboxylase;


Pssm-ID: 236128  Cd Length: 349  Bit Score: 46.92  E-value: 9.72e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 186 LVVIDAAynefasFKDSKKHlEPCELI-KEFDNVLYLGTFSKLYGLGGLRIGYGIADASIISAFYKLRAPFNVSNLALKA 264
Cdd:PRK07908 170 ILVVDEA------FADAVPG-EPESLAgDDLPGVLVLRSLTKTWSLAGLRVGYALGAPDVLARLTRGRAHWPVGTLQLEA 242


                 ....*...
gi 489011712 265 AVAAMDDD 272
Cdd:PRK07908 243 IAACCAPR 250
PRK06290 PRK06290
LL-diaminopimelate aminotransferase;
24-280 9.92e-06

LL-diaminopimelate aminotransferase;


Pssm-ID: 235772  Cd Length: 410  Bit Score: 46.95  E-value: 9.92e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  24 KEYGVKEVIKLASNENPFGTPPKAIECLRQNANKAH--LYPDDSMIELKSTLAQ----KYKVQN----ENIIIGAGSDQV 93
Cdd:PRK06290  39 EKHPDMELIDMGVGEPDEMADESVVEVLCEEAKKPEnrGYADNGIQEFKEAAARymekVFGVKDidpvTEVIHSIGSKPA 118

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  94 IefaihAKLNSknAFLQAG----VTFAMYEI---YAKQCGAKCYKTQSITHN--LDEFKKLYETHKDEIKLIFLCLPNNP 164
Cdd:PRK06290 119 L-----AMLPS--CFINPGdvtlMTVPGYPVtgtHTKYYGGEVYNLPLLEENnfLPDLDSIPKDIKEKAKLLYLNYPNNP 191

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 165 LGecldASEVTKFIKGV-----EEDCLVVIDAAYNE---------FASFKDSKkhlepcelikefDNVLYLGTFSKLYGL 230
Cdd:PRK06290 192 TG----AVATKEFYEEVvdfakENNIIVVQDAAYAAltfdgkplsFLSVPGAK------------EVGVEIHSLSKAYNM 255

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|..
gi 489011712 231 GGLRIGYGIADASIISAFYKLRAPFNVSN-LAL-KAAVAAMDDDEFTEKTLE 280
Cdd:PRK06290 256 TGWRLAFVVGNELIVKAFATVKDNNDSGQfIAIqKAGIYALDHPEITEKIRE 307
PLN02376 PLN02376
1-aminocyclopropane-1-carboxylate synthase
 142-298 1.58e-05

1-aminocyclopropane-1-carboxylate synthase


Pssm-ID: 178004 [Multi-domain]  Cd Length: 496  Bit Score: 46.61  E-value: 1.58e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 142 FKKLYETHKdEIKLIFLCLPNNPLGECLDASEVTKFIKGV-EEDCLVVIDAAY-------NEFASFKDSKKHLEPCELIK 213
Cdd:PLN02376 190 YKKAQESNK-KVKGLILTNPSNPLGTMLDKDTLTNLVRFVtRKNIHLVVDEIYaatvfagGDFVSVAEVVNDVDISEVNV 268

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 214 EFDNVLYlgTFSKLYGLGGLRIG--YGIADaSIISAFYKLRAPFNVSNLALKAAVAAMDDDEFTEKTLennfsqMELYKE 291
Cdd:PLN02376 269 DLIHIVY--SLSKDMGLPGFRVGivYSFND-SVVSCARKMSSFGLVSSQTQLMLASMLSDDQFVDNFL------MESSRR 339


                 ....*..
gi 489011712 292 FAKKHNI 298
Cdd:PLN02376 340 LGIRHKV 346
PRK07324 PRK07324
transaminase; Validated
 139-327 2.59e-05

transaminase; Validated


Pssm-ID: 235989  Cd Length: 373  Bit Score: 45.70  E-value: 2.59e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 139 LDEFKKLYethKDEIKLIFLCLPNNPLGECLDAS---EVTKFIKGVeeDCLVVIDAAYNEFASFKDSkkhlepCELIKEF 215
Cdd:PRK07324 143 LDELRRLV---RPNTKLICINNANNPTGALMDRAyleEIVEIARSV--DAYVLSDEVYRPLDEDGST------PSIADLY 211

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 216 DNVLYLGTFSKLYGLGGLRIGYGIADASIISAFYKLRAPFNVSnlalkaavAAMDDDEFTEKTLENNFSQMELYKEFAKK 295
Cdd:PRK07324 212 EKGISTNSMSKTYSLPGIRVGWIAANEEVIDILRKYRDYTMIC--------AGVFDDMLASLALEHRDAILERNRKIVRT 283

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 489011712 296 hNIKIID---------SY-------TNFITYFFDEKnSTDLSEKLLKK 327
Cdd:PRK07324 284 -NLAILDewvakeprvSYvkpkavsTSFVKLDVDMP-SEDFCLKLLKE 329
tyr_nico_aTase TIGR01265
tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal ...
 76-237 3.00e-05

tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal phosphate-dependent enzymes includes known examples of both tyrosine aminotransferase from animals and nicotianamine aminotransferase from barley.


Pssm-ID: 188123  Cd Length: 403  Bit Score: 45.41  E-value: 3.00e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712   76 KYKVQNENIIIGAGSDQVIEFAIHAKLNSKNAFLQAGVTFAMYEIYAKQCGA-----KCYKTQSITHNLDEFkklyETHK 150
Cdd:TIGR01265  91 PGKLTADDVVLTSGCSQAIEICIEALANPGANILVPRPGFPLYDTRAAFSGLevrlyDLLPEKDWEIDLDGL----ESLA 166

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  151 DE-IKLIFLCLPNNPLGECLDASEVTKFIKGVEEDCLVVI-DAAYNEFAsFKDSkkhlePCELIKEFDN---VLYLGTFS 225
Cdd:TIGR01265 167 DEkTVAIVVINPSNPCGSVFSRDHLQKIAEVAEKLGIPIIaDEIYGHMV-FGDA-----PFIPMASFASivpVLSLGGIS 240

                         170
                  ....*....|..
gi 489011712  226 KLYGLGGLRIGY 237
Cdd:TIGR01265 241 KRWVVPGWRLGW 252
PRK07309 PRK07309
pyridoxal phosphate-dependent aminotransferase;
27-271 4.54e-05

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 235985  Cd Length: 391  Bit Score: 45.10  E-value: 4.54e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  27 GVKEVIKLASNENPFGTPP-------KAIEclrqnANKAHLYPDDSMIELKSTLAQ--------KYKVQNEnIIIGAGSD 91
Cdd:PRK07309  28 DIPGILKLTLGEPDFTTPDhvkeaakRAID-----ANQSHYTGMAGLLELRQAAADfvkekynlDYAPENE-ILVTIGAT 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  92 QVIEFAIHAKLNSKNAFLQAGVTFAMYEIYAKQCGAKCYKTQSITHNL----DEFKKLYETHKDEIKLIFLCLPNNPLGE 167
Cdd:PRK07309 102 EALSASLTAILEPGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENDFvltpEMLEKAILEQGDKLKAVILNYPANPTGV 181

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 168 CLDASEVTKFIKGVEE-DCLVVIDAAYNEFASFKDSkkHLEPCELIKefDNVLYLGTFSKLYGLGGLRIGYGIADASIIS 246
Cdd:PRK07309 182 TYSREQIKALADVLKKyDIFVISDEVYSELTYTGEP--HVSIAEYLP--DQTILINGLSKSHAMTGWRIGLIFAPAEFTA 257

                        250       260       270
                 ....*....|....*....|....*....|.
gi 489011712 247 AF-----YKLRAPFNVSNLA-LKAAVAAMDD 271
Cdd:PRK07309 258 QLikshqYLVTAATTMAQFAaVEALTNGKDD 288
PRK08068 PRK08068
transaminase; Reviewed
 139-273 5.06e-05

transaminase; Reviewed


Pssm-ID: 181219  Cd Length: 389  Bit Score: 44.92  E-value: 5.06e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 139 LDEFKKLYETHKDEIKLIFLCLPNNPLGECLDAS---EVTKFIKgvEEDCLVVIDAAYNEFAsFkDSKKHLE--PCELIK 213
Cdd:PRK08068 154 LPDYTKIPEEVAEKAKLMYLNYPNNPTGAVATKAffeETVAFAK--KHNIGVVHDFAYGAIG-F-DGQKPVSflQTPGAK 229

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489011712 214 EFDNVLYlgTFSKLYGLGGLRIGYGIADASIISAFYKLRAPFNVSNL-ALK-AAVAAMDDDE 273
Cdd:PRK08068 230 DVGIELY--TLSKTFNMAGWRVAFAVGNESVIEAINLLQDHLFVSLFgAIQdAAIEALLSDQ 289
PTZ00377 PTZ00377
alanine aminotransferase; Provisional
 138-269 4.08e-04

alanine aminotransferase; Provisional


Pssm-ID: 240391 [Multi-domain]  Cd Length: 481  Bit Score: 42.26  E-value: 4.08e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 138 NLDEFKKLYETHKDE---IKLIFLCLPNNPLGECLDASEVTKFIK-GVEEDCLVVIDAAYNE--------FASFkdsKKH 205
Cdd:PTZ00377 201 DQEELEEAYEQAVRNgitPRALVVINPGNPTGQVLTRDVMEEIIKfCYEKGIVLMADEVYQEniydgekpFISF---RKV 277

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489011712 206 LepCELIKEFDNVLYLGTF---SK-LYGLGGLRIGY----GIaDASIISAFYKLRAPFNVSNLALKAAVAAM 269
Cdd:PTZ00377 278 L--LELPAEYNTDVELVSFhstSKgIIGECGRRGGYfeltNI-PPEVREQIYKLASINLCSNVVGQLMTGLM 346
tyr_amTase_E TIGR01264
tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found ...
 82-239 4.61e-04

tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found in animals and Trypanosoma cruzi. It is the first enzyme of a pathway of tyrosine degradation via homogentisate. Several plant enzyme designated as probable tyrosine aminotransferases are very closely related to an experimentally demonstrated nicotianamine aminotransferase, an enzyme in a siderophore (iron uptake chelator) biosynthesis pathway. These plant sequences are excluded from the model seed and score between the trusted an noise cutoffs. [Energy metabolism, Amino acids and amines]


Pssm-ID: 273529 [Multi-domain]  Cd Length: 401  Bit Score: 41.69  E-value: 4.61e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712   82 ENIIIGAGSDQVIEFAIHAKLNSKNAFLQAGVTFAMYEIYAKQCGA-----KCYKTQSITHNLDEFKKLYEthkDEIKLI 156
Cdd:TIGR01264  96 DDVVLCSGCSHAIEMCIAALANAGQNILVPRPGFPLYETLAESMGIevklyNLLPDKSWEIDLKQLESLID---EKTAAL 172

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  157 FLCLPNNPLGECLDASEVTKFIKGVEEDCLVVI-DAAYNEFAsFKDSKkhLEPCELIKEFDNVLYLGTFSKLYGLGGLRI 235
Cdd:TIGR01264 173 IVNNPSNPCGSVFSRQHLEEILAVAERQCLPIIaDEIYGDMV-FSGAT--FEPLASLSSTVPILSCGGLAKRWLVPGWRL 249


                  ....
gi 489011712  236 GYGI 239
Cdd:TIGR01264 250 GWII 253
avtA PRK09440
valine--pyruvate transaminase; Provisional
 151-248 1.19e-03

valine--pyruvate transaminase; Provisional


Pssm-ID: 236517  Cd Length: 416  Bit Score: 40.61  E-value: 1.19e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 151 DEIKLIFLCLPNNPLGECLDASEVTKFIK-GVEEDCLVVIDAAY-NEFAS--FKDSKKHLEPcelikefdNVLYLGTFSK 226
Cdd:PRK09440 178 EDTGAICVSRPTNPTGNVLTDEELEKLDAlARQHNIPLLIDNAYgPPFPGiiFSEATPLWNP--------NIILCMSLSK 249

                         90       100
                 ....*....|....*....|..
gi 489011712 227 LyGLGGLRIGYGIADASIISAF 248
Cdd:PRK09440 250 L-GLPGVRCGIVIADEEIIEAL 270
PRK08960 PRK08960
pyridoxal phosphate-dependent aminotransferase;
161-280 1.74e-03

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 181595  Cd Length: 387  Bit Score: 40.04  E-value: 1.74e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 161 PNNPLGECLDASEVTKFIKGVEE-DCLVVIDAAYNEFASFKDSKKHLEPCelikefDNVLYLGTFSKLYGLGGLRIGYGI 239
Cdd:PRK08960 174 PANPTGTLLSRDELAALSQALRArGGHLVVDEIYHGLTYGVDAASVLEVD------DDAFVLNSFSKYFGMTGWRLGWLV 247

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 489011712 240 ADASIISAFYKLRAPFNVS--NLALKAAVAAmdddeFTEKTLE 280
Cdd:PRK08960 248 APPAAVPELEKLAQNLYISasTPAQHAALAC-----FEPETLA 285
PRK06836 PRK06836
pyridoxal phosphate-dependent aminotransferase;
23-237 3.63e-03

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 180720  Cd Length: 394  Bit Score: 39.02  E-value: 3.63e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  23 AKEYGVKEVIKLaSNENPFGTPPKAI-ECLRQNANKA----HLY-PDDSMIELKSTLAQKY------KVQNENIII--GA 88
Cdd:PRK06836  27 KAEYGADNVFDF-SLGNPSVPPPAAVkEALRELAEEEdpglHGYmPNAGYPEVREAIAESLnrrfgtPLTADHIVMtcGA 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712  89 G-------------SDQVIEFAIHaklnsknaflqagvtFAMYEIYAKQCGAKC----YKTQSITHNLDEFKKLYeTHKd 151
Cdd:PRK06836 106 AgalnvalkailnpGDEVIVFAPY---------------FVEYRFYVDNHGGKLvvvpTDTDTFQPDLDALEAAI-TPK- 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489011712 152 eIKLIFLCLPNNPLGECLDASEVTKFIKGVEE-------DCLVVIDAAYNEFAsFKDSKKhlePCeLIKEFDNVLYLGTF 224
Cdd:PRK06836 169 -TKAVIINSPNNPTGVVYSEETLKALAALLEEkskeygrPIYLISDEPYREIV-YDGAEV---PY-IFKYYDNSIVVYSF 242

                        250
                 ....*....|...
gi 489011712 225 SKLYGLGGLRIGY 237
Cdd:PRK06836 243 SKSLSLPGERIGY 255
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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