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Conserved domains on  [gi|488473090|ref|WP_002516760|]
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MULTISPECIES: (d)CMP kinase [Bacteria]

Protein Classification

(d)CMP kinase( domain architecture ID 10785233)

(d)CMP kinase catalyzes the phosphorylation of cytidine monophosphate (CMP) or dCMP to produce cytidine diphosphate (CDP) or dCDP, using ATP as the preferred phosphoryl donor

CATH:  3.40.50.300
Gene Ontology:  GO:0036431|GO:0006220|GO:0005524
PubMed:  10218107

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Cmk COG0283
Cytidylate kinase [Nucleotide transport and metabolism];
6-218 1.30e-85

Cytidylate kinase [Nucleotide transport and metabolism];


:

Pssm-ID: 440052 [Multi-domain]  Cd Length: 220  Bit Score: 252.64  E-value: 1.30e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488473090   6 LVIAIDGPSGSGKSSTSRGVANRLGLARLDTGSMYRAVACRVAHLGIDPtTNPRDAIKVAQSCHLEIDTSAIDDRVVIDG 85
Cdd:COG0283    1 PVIAIDGPAGSGKSTVAKALAKRLGYHYLDTGAMYRAVALAALRNGIDL-DDEEALAALARNLDIEFETDPGGQRVFLNG 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488473090  86 EDVTKEIRDPQTSAKVSAVATIQPVRDALTARMRQVAADRGrIVMEGRDITTVVCPDAQVRVLLVADPAIRVARRQAEL- 164
Cdd:COG0283   80 EDVTDEIRTEEVSNAVSKVAAIPEVREALVALQRAFAKAPG-LVADGRDIGTVVFPDAELKIFLTASAEERARRRYKELk 158

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 488473090 165 --GEKVDMAQVIDSIVRRDRDDSTVST-FEEPAEGVTVVDSTHLNLDQVIDAVIDLV 218
Cdd:COG0283  159 ekGISVSLEELLADIKERDERDSTRAVaPLKPAEDAIVIDTTDLSIEEVVEKILALV 215
 
Name Accession Description Interval E-value
Cmk COG0283
Cytidylate kinase [Nucleotide transport and metabolism];
6-218 1.30e-85

Cytidylate kinase [Nucleotide transport and metabolism];


Pssm-ID: 440052 [Multi-domain]  Cd Length: 220  Bit Score: 252.64  E-value: 1.30e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488473090   6 LVIAIDGPSGSGKSSTSRGVANRLGLARLDTGSMYRAVACRVAHLGIDPtTNPRDAIKVAQSCHLEIDTSAIDDRVVIDG 85
Cdd:COG0283    1 PVIAIDGPAGSGKSTVAKALAKRLGYHYLDTGAMYRAVALAALRNGIDL-DDEEALAALARNLDIEFETDPGGQRVFLNG 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488473090  86 EDVTKEIRDPQTSAKVSAVATIQPVRDALTARMRQVAADRGrIVMEGRDITTVVCPDAQVRVLLVADPAIRVARRQAEL- 164
Cdd:COG0283   80 EDVTDEIRTEEVSNAVSKVAAIPEVREALVALQRAFAKAPG-LVADGRDIGTVVFPDAELKIFLTASAEERARRRYKELk 158

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 488473090 165 --GEKVDMAQVIDSIVRRDRDDSTVST-FEEPAEGVTVVDSTHLNLDQVIDAVIDLV 218
Cdd:COG0283  159 ekGISVSLEELLADIKERDERDSTRAVaPLKPAEDAIVIDTTDLSIEEVVEKILALV 215
PRK09518 PRK09518
bifunctional cytidylate kinase/GTPase Der; Reviewed
 6-218 1.63e-54

bifunctional cytidylate kinase/GTPase Der; Reviewed


Pssm-ID: 236546 [Multi-domain]  Cd Length: 712  Bit Score: 185.00  E-value: 1.63e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488473090   6 LVIAIDGPSGSGKSSTSRGVANRLGLARLDTGSMYRAVACRVAHLGIDPTTNPRDAIKVAQSC-------HLEIDTSAID 78
Cdd:PRK09518   2 IIVAIDGPAGVGKSSVSRALAQYLGYAYLDTGAMYRACAWWCLKQGIDLDAELVDEQVVTEAVgefftglHFDISVDPDS 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488473090  79 DRVVIDGEDVTKEIRDPQTSAKVSAVATIQPVRDALTARMRQVAADRG---------RIVMEGRDITTVVCPDAQVRVLL 149
Cdd:PRK09518  82 PGVFADGEDISEEIRSPEVSSHVSAVAAIPPVRNVLIAAQRAYIAREAsadsfsgglGIVAEGRDITTVVAPDAEVRILL 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 488473090 150 VADPAIRVARRQAELGEKVDMAqVIDSIVRRDRDDSTVSTFEEPAEGVTVVDSTHLNLDQVIDAVIDLV 218
Cdd:PRK09518 162 TAREEVRQARRSGQDRSETPGV-VLEDVAARDEADSKVTSFLSAADGVTTLDNSDLDFDETLDLLIGLV 229
Cytidylate_kin pfam02224
Cytidylate kinase; Cytidylate kinase EC:2.7.4.14 catalyzes the phosphorylation of cytidine 5 ...
 8-219 5.27e-54

Cytidylate kinase; Cytidylate kinase EC:2.7.4.14 catalyzes the phosphorylation of cytidine 5'-monophosphate (dCMP) to cytidine 5'-diphosphate (dCDP) in the presence of ATP or GTP.


Pssm-ID: 280401 [Multi-domain]  Cd Length: 211  Bit Score: 172.10  E-value: 5.27e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488473090    8 IAIDGPSGSGKSSTSRGVANRLGLARLDTGSMYRAVACRVAHLGIDPTtnprDAIKVAQSChLEIDTSAIDDRVVIDGED 87
Cdd:pfam02224   1 IAIDGPSGSGKSTVARILARKLGYKYLDTGAMYRALALAALRQKVDLT----DEDALAELA-SEVDISFGHTEVFLNGED 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488473090   88 VTKEIRDPQTSAKVSAVATIQPVRDALTARMRQVaADRGRIVMEGRDITTVVCPDAQVRVLLVADPAIRVARRQAELGEK 167
Cdd:pfam02224  76 VSSEIRTDEVAQAASQVAAIPAVRARLNKLQRQL-AKNGNIVMEGRDIGTVVFPDAEVKIFLTASPEERAKRRYKQLQAK 154

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 488473090  168 ---VDMAQVIDSIVRRDRDDST--VSTFeEPAEGVTVVDSTHLNLDQVIDAVIDLVP 219
Cdd:pfam02224 155 glsVDFEELLAEIKRRDKRDSEraVGPL-KPAPDALIIDTSKLTIEEVVEKILELIK 210
cmk TIGR00017
cytidylate kinase; This family consists of cytidylate kinase, which catalyzes the ...
 6-218 7.44e-48

cytidylate kinase; This family consists of cytidylate kinase, which catalyzes the phosphorylation of cytidine 5-monophosphate (dCMP) to cytidine 5 -diphosphate (dCDP) in the presence of ATP or GTP. UMP and dCMP can also act as acceptors. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]


Pssm-ID: 129128 [Multi-domain]  Cd Length: 217  Bit Score: 156.82  E-value: 7.44e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488473090    6 LVIAIDGPSGSGKSSTSRGVANRLGLARLDTGSMYRAVACRVAHLGIDPTTNPrDAIKVAQSCHLEIDTSAIDDRVVIDG 85
Cdd:TIGR00017   3 MIIAIDGPSGAGKSTVAKAVAEKLGYAYLDSGAMYRAIALAALQNRVDLTSED-ALAELISHLDIRFIPTNGEVEVFLNG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488473090   86 EDVTKEIRDPQTSAKVSAVATIQPVRDALTARMRQVaADRGRIVMEGRDITTVVCPDAQVRVLLVADPAIRVARRQAELG 165
Cdd:TIGR00017  82 EDVSEAIRTQEVANAASKVAVFPKVREALLKRQQAL-AKNDGIIADGRDIGTVVFPNAEVKIFLDASVEERAKRRYKQLQ 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 488473090  166 EK---VDMAQVIDSIVRRDRDDS--TVSTFeEPAEGVTVVDSTHLNLDQVIDAVIDLV 218
Cdd:TIGR00017 161 IKgneVNFEELLAEIKERDDRDSnrEVAPL-KKADDALYLDTSNLSIDEVVEKILEYA 217
CMPK cd02020
Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine ...
 7-203 8.86e-42

Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor.


Pssm-ID: 238978 [Multi-domain]  Cd Length: 147  Bit Score: 138.77  E-value: 8.86e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488473090   7 VIAIDGPSGSGKSSTSRGVANRLGLARLDTGsmyravacrvahlgidpttnprdaikvaqschleidtsaiddrvvidge 86
Cdd:cd02020    1 IIAIDGPAGSGKSTVAKLLAKKLGLPYLDTG------------------------------------------------- 31

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488473090  87 dvtkEIRDPQTSAKVSAVATIQPVRDALTARMRQVAADRGrIVMEGRDITTVVCPDAQVRVLLVADPAIRVARRQAEL-- 164
Cdd:cd02020   32 ----GIRTEEVGKLASEVAAIPEVRKALDERQRELAKKPG-IVLEGRDIGTVVFPDADLKIFLTASPEVRAKRRAKQLqa 106

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 488473090 165 -GEKVDMAQVIDSIVRRDRDDSTVST-FEEPAEGVTVVDST 203
Cdd:cd02020  107 kGEGVDLEEILAEIIERDERDSTRYVaPLKLAEDAIVIDTS 147
 
Name Accession Description Interval E-value
Cmk COG0283
Cytidylate kinase [Nucleotide transport and metabolism];
6-218 1.30e-85

Cytidylate kinase [Nucleotide transport and metabolism];


Pssm-ID: 440052 [Multi-domain]  Cd Length: 220  Bit Score: 252.64  E-value: 1.30e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488473090   6 LVIAIDGPSGSGKSSTSRGVANRLGLARLDTGSMYRAVACRVAHLGIDPtTNPRDAIKVAQSCHLEIDTSAIDDRVVIDG 85
Cdd:COG0283    1 PVIAIDGPAGSGKSTVAKALAKRLGYHYLDTGAMYRAVALAALRNGIDL-DDEEALAALARNLDIEFETDPGGQRVFLNG 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488473090  86 EDVTKEIRDPQTSAKVSAVATIQPVRDALTARMRQVAADRGrIVMEGRDITTVVCPDAQVRVLLVADPAIRVARRQAEL- 164
Cdd:COG0283   80 EDVTDEIRTEEVSNAVSKVAAIPEVREALVALQRAFAKAPG-LVADGRDIGTVVFPDAELKIFLTASAEERARRRYKELk 158

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 488473090 165 --GEKVDMAQVIDSIVRRDRDDSTVST-FEEPAEGVTVVDSTHLNLDQVIDAVIDLV 218
Cdd:COG0283  159 ekGISVSLEELLADIKERDERDSTRAVaPLKPAEDAIVIDTTDLSIEEVVEKILALV 215
PRK09518 PRK09518
bifunctional cytidylate kinase/GTPase Der; Reviewed
 6-218 1.63e-54

bifunctional cytidylate kinase/GTPase Der; Reviewed


Pssm-ID: 236546 [Multi-domain]  Cd Length: 712  Bit Score: 185.00  E-value: 1.63e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488473090   6 LVIAIDGPSGSGKSSTSRGVANRLGLARLDTGSMYRAVACRVAHLGIDPTTNPRDAIKVAQSC-------HLEIDTSAID 78
Cdd:PRK09518   2 IIVAIDGPAGVGKSSVSRALAQYLGYAYLDTGAMYRACAWWCLKQGIDLDAELVDEQVVTEAVgefftglHFDISVDPDS 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488473090  79 DRVVIDGEDVTKEIRDPQTSAKVSAVATIQPVRDALTARMRQVAADRG---------RIVMEGRDITTVVCPDAQVRVLL 149
Cdd:PRK09518  82 PGVFADGEDISEEIRSPEVSSHVSAVAAIPPVRNVLIAAQRAYIAREAsadsfsgglGIVAEGRDITTVVAPDAEVRILL 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 488473090 150 VADPAIRVARRQAELGEKVDMAqVIDSIVRRDRDDSTVSTFEEPAEGVTVVDSTHLNLDQVIDAVIDLV 218
Cdd:PRK09518 162 TAREEVRQARRSGQDRSETPGV-VLEDVAARDEADSKVTSFLSAADGVTTLDNSDLDFDETLDLLIGLV 229
Cytidylate_kin pfam02224
Cytidylate kinase; Cytidylate kinase EC:2.7.4.14 catalyzes the phosphorylation of cytidine 5 ...
 8-219 5.27e-54

Cytidylate kinase; Cytidylate kinase EC:2.7.4.14 catalyzes the phosphorylation of cytidine 5'-monophosphate (dCMP) to cytidine 5'-diphosphate (dCDP) in the presence of ATP or GTP.


Pssm-ID: 280401 [Multi-domain]  Cd Length: 211  Bit Score: 172.10  E-value: 5.27e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488473090    8 IAIDGPSGSGKSSTSRGVANRLGLARLDTGSMYRAVACRVAHLGIDPTtnprDAIKVAQSChLEIDTSAIDDRVVIDGED 87
Cdd:pfam02224   1 IAIDGPSGSGKSTVARILARKLGYKYLDTGAMYRALALAALRQKVDLT----DEDALAELA-SEVDISFGHTEVFLNGED 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488473090   88 VTKEIRDPQTSAKVSAVATIQPVRDALTARMRQVaADRGRIVMEGRDITTVVCPDAQVRVLLVADPAIRVARRQAELGEK 167
Cdd:pfam02224  76 VSSEIRTDEVAQAASQVAAIPAVRARLNKLQRQL-AKNGNIVMEGRDIGTVVFPDAEVKIFLTASPEERAKRRYKQLQAK 154

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 488473090  168 ---VDMAQVIDSIVRRDRDDST--VSTFeEPAEGVTVVDSTHLNLDQVIDAVIDLVP 219
Cdd:pfam02224 155 glsVDFEELLAEIKRRDKRDSEraVGPL-KPAPDALIIDTSKLTIEEVVEKILELIK 210
PRK13477 PRK13477
bifunctional pantoate--beta-alanine ligase/(d)CMP kinase;
1-217 8.59e-53

bifunctional pantoate--beta-alanine ligase/(d)CMP kinase;


Pssm-ID: 237393 [Multi-domain]  Cd Length: 512  Bit Score: 177.38  E-value: 8.59e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488473090   1 MSTSPLvIAIDGPSGSGKSSTSRGVANRLGLARLDTGSMYRAVACRVAHLGIDPTtnprDAIKVAQS---CHLEIDTSAI 77
Cdd:PRK13477 281 MKRQPI-IAIDGPAGAGKSTVTRAVAKKLGLLYLDTGAMYRAVTWLVLQEGIDPQ----DEEALAELlsdLKIELKPSSG 355

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488473090  78 DD-RVVIDGEDVTKEIRDPQTSAKVSAVATIQPVRDALTARMRQVAAdRGRIVMEGRDITTVVCPDAQVRVLLVADPAIR 156
Cdd:PRK13477 356 SPqRVWINGEDVTEAIRSPEVTSSVSAIAAQPAVRQALVKQQQRIGE-KGGLVAEGRDIGTHVFPDAELKIFLTASVEER 434

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 488473090 157 VARRQAELGEK----VDMAQVIDSIVRRDRDDST--VSTFeEPAEGVTVVDSTHLNLDQVIDAVIDL 217
Cdd:PRK13477 435 ARRRALDLQAQgfpvIDLEQLEAQIAERDRLDSTreIAPL-RKADDAIELITDGLSIEEVVDKIIDL 500
cmk TIGR00017
cytidylate kinase; This family consists of cytidylate kinase, which catalyzes the ...
 6-218 7.44e-48

cytidylate kinase; This family consists of cytidylate kinase, which catalyzes the phosphorylation of cytidine 5-monophosphate (dCMP) to cytidine 5 -diphosphate (dCDP) in the presence of ATP or GTP. UMP and dCMP can also act as acceptors. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]


Pssm-ID: 129128 [Multi-domain]  Cd Length: 217  Bit Score: 156.82  E-value: 7.44e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488473090    6 LVIAIDGPSGSGKSSTSRGVANRLGLARLDTGSMYRAVACRVAHLGIDPTTNPrDAIKVAQSCHLEIDTSAIDDRVVIDG 85
Cdd:TIGR00017   3 MIIAIDGPSGAGKSTVAKAVAEKLGYAYLDSGAMYRAIALAALQNRVDLTSED-ALAELISHLDIRFIPTNGEVEVFLNG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488473090   86 EDVTKEIRDPQTSAKVSAVATIQPVRDALTARMRQVaADRGRIVMEGRDITTVVCPDAQVRVLLVADPAIRVARRQAELG 165
Cdd:TIGR00017  82 EDVSEAIRTQEVANAASKVAVFPKVREALLKRQQAL-AKNDGIIADGRDIGTVVFPNAEVKIFLDASVEERAKRRYKQLQ 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 488473090  166 EK---VDMAQVIDSIVRRDRDDS--TVSTFeEPAEGVTVVDSTHLNLDQVIDAVIDLV 218
Cdd:TIGR00017 161 IKgneVNFEELLAEIKERDDRDSnrEVAPL-KKADDALYLDTSNLSIDEVVEKILEYA 217
CMPK cd02020
Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine ...
 7-203 8.86e-42

Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor.


Pssm-ID: 238978 [Multi-domain]  Cd Length: 147  Bit Score: 138.77  E-value: 8.86e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488473090   7 VIAIDGPSGSGKSSTSRGVANRLGLARLDTGsmyravacrvahlgidpttnprdaikvaqschleidtsaiddrvvidge 86
Cdd:cd02020    1 IIAIDGPAGSGKSTVAKLLAKKLGLPYLDTG------------------------------------------------- 31

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488473090  87 dvtkEIRDPQTSAKVSAVATIQPVRDALTARMRQVAADRGrIVMEGRDITTVVCPDAQVRVLLVADPAIRVARRQAEL-- 164
Cdd:cd02020   32 ----GIRTEEVGKLASEVAAIPEVRKALDERQRELAKKPG-IVLEGRDIGTVVFPDADLKIFLTASPEVRAKRRAKQLqa 106

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 488473090 165 -GEKVDMAQVIDSIVRRDRDDSTVST-FEEPAEGVTVVDST 203
Cdd:cd02020  107 kGEGVDLEEILAEIIERDERDSTRYVaPLKLAEDAIVIDTS 147
PRK11860 PRK11860
bifunctional 3-phosphoshikimate 1-carboxyvinyltransferase/cytidylate kinase;
7-218 4.72e-34

bifunctional 3-phosphoshikimate 1-carboxyvinyltransferase/cytidylate kinase;


Pssm-ID: 237003 [Multi-domain]  Cd Length: 661  Bit Score: 128.24  E-value: 4.72e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488473090   7 VIAIDGPSGSGKSSTSRGVANRLGLARLDTGSMYRAVACRVAHLGIDPTTNPRDAiKVAQSCHLEIDTsaidDRVVIDGE 86
Cdd:PRK11860 444 VICIDGPTASGKGTVAARVAEALGYHYLDSGALYRLTALAALRAGVALDDEAAIA-ALARGLPVRFEG----DRIWLGGE 518

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488473090  87 DVTKEIRDPQTSAKVSAVATIQPVRDALTARMRQVAADRGrIVMEGRDITTVVCPDAQVRVLLVADPAIRVARRQAELGE 166
Cdd:PRK11860 519 DVTDAIRTEAAGMGASRVSALPAVRAALLALQRSFRRLPG-LVADGRDMGTVIFPDAALKVFLTASAEARAERRYKQLIS 597

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 488473090 167 K---VDMAQVIDSIVRRDRDDSTVSTFE-EPAEGVTVVDSTHLNLDQVIDAVIDLV 218
Cdd:PRK11860 598 KgisANIADLLADLEARDARDTQRSVAPlKPAQDALLLDNSDLTIEQAVAQVLDWW 653
PRK12269 PRK12269
bifunctional cytidylate kinase/ribosomal protein S1; Provisional
 6-214 1.61e-20

bifunctional cytidylate kinase/ribosomal protein S1; Provisional


Pssm-ID: 105491 [Multi-domain]  Cd Length: 863  Bit Score: 89.39  E-value: 1.61e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488473090   6 LVIAIDGPSGSGKSSTSRGVANRLGLARLDTGSMYRAVAC----RVAHLGI---DPTTNPRDAIKVAQSCH-LEIDTS-- 75
Cdd:PRK12269  35 VIIALDGPAGSGKSSVCRLLASRLGAQCLNTGSFYRAFTLaalrRVSELAVqacSPSPDPDAAVGCAAVPHaTNLDTSya 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488473090  76 --------AIDDR------------------VVIDGEDVTKEIRDPQTSAKVSAVATIQPVRDALTARMRQvAADRGRIV 129
Cdd:PRK12269 115 pltaqkkvALFDEaywvsfartvalsyragvMYVGEENVESLLRSDEVESAVSYFAAMPAIRAIMTGKIRS-AVCGARVV 193

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488473090 130 MEGRDITTVVCPDAQVRVLLVADPAIRVARRQAELGEKVDMAQVIDSIVRRDRDD--STVSTFeEPAEGVTVVDSTHLNL 207
Cdd:PRK12269 194 CEGRDLTTVVFVDADLKCYLDASIEARVARRWAQGTSRLSKQELEQRMRARDAHDraRTVGGL-RCAPDALYVDTSCLTI 272


                 ....*..
gi 488473090 208 DQVIDAV 214
Cdd:PRK12269 273 EEVCERI 279
PRK04182 PRK04182
cytidylate kinase; Provisional
 6-182 7.29e-07

cytidylate kinase; Provisional


Pssm-ID: 235244 [Multi-domain]  Cd Length: 180  Bit Score: 47.88  E-value: 7.29e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488473090   6 LVIAIDGPSGSGKSSTSRGVANRLGLARLDTGSMYRAVAcrvAHLGIDPTtnprDAIKVAQScHLEIDtSAIDdrvvidg 85
Cdd:PRK04182   1 MIITISGPPGSGKTTVARLLAEKLGLKHVSAGEIFRELA---KERGMSLE----EFNKYAEE-DPEID-KEID------- 64

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488473090  86 edvtkeirdpqtsakvsavatiqpvrdaltARMRQVAADRGRIVMEGRDITTVVCPDAQVRVLLVADP---AIRVARRqa 162
Cdd:PRK04182  65 ------------------------------RRQLEIAEKEDNVVLEGRLAGWMAKDYADLKIWLKAPLevrAERIAER-- 112

                        170       180
                 ....*....|....*....|
gi 488473090 163 elgEKVDMAQVIDSIVRRDR 182
Cdd:PRK04182 113 ---EGISVEEALEETIEREE 129
Udk COG0572
Uridine kinase [Nucleotide transport and metabolism]; Uridine kinase is part of the Pathway ...
 1-30 3.28e-06

Uridine kinase [Nucleotide transport and metabolism]; Uridine kinase is part of the Pathway/BioSystem: Pyrimidine salvage


Pssm-ID: 440337 [Multi-domain]  Cd Length: 206  Bit Score: 45.99  E-value: 3.28e-06
                         10        20        30
                 ....*....|....*....|....*....|
gi 488473090   1 MSTSPLVIAIDGPSGSGKSSTSRGVANRLG 30
Cdd:COG0572    3 RSGKPRIIGIAGPSGSGKTTFARRLAEQLG 32
CmkB COG1102
Cytidylate kinase [Nucleotide transport and metabolism];
6-218 5.71e-06

Cytidylate kinase [Nucleotide transport and metabolism];


Pssm-ID: 440719 [Multi-domain]  Cd Length: 188  Bit Score: 45.20  E-value: 5.71e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488473090   6 LVIAIDGPSGSGKSSTSRGVANRLGLARLDtGSMYRAVAcrvAHLGIDpttnPRDAIKVAQSCHLEIDTS-AIDDRVVID 84
Cdd:COG1102    1 MVITISREPGSGGTTIAKRLAEKLGLPLYD-GEILREAA---KERGLS----EEEFEKLDEKAPSLLYRDtAEEDEIDRA 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488473090  85 GEDVTKEIrdpqtsakvsavatiqpvrdaltarmrqvaADRGRIVMEGRdITTVVCPDAQ--VRVLLVADPAIRVARRQA 162
Cdd:COG1102   73 LDKVIREL------------------------------ARKGNCVIVGR-LADWILRDRPnvLKVFLTAPLEVRVKRIAE 121

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488473090 163 ElgEKVDMAQVIDSIVRRDR--------------DDSTVSTFeepaegvtVVDSTHLNLDQVIDAVIDLV 218
Cdd:COG1102  122 R--EGISEEEAEKEIKKRDKsrakyykyyygidwGDPSNYDL--------VINTSRLGIEEAVDLILAAI 181
Pgk2 COG2074
2-phosphoglycerate kinase/Mevalonate-3-phosphate 5-kinase [Carbohydrate transport and ...
 1-34 2.91e-03

2-phosphoglycerate kinase/Mevalonate-3-phosphate 5-kinase [Carbohydrate transport and metabolism, Lipid transport and metabolism];


Pssm-ID: 441677  Cd Length: 207  Bit Score: 37.62  E-value: 2.91e-03
                         10        20        30
                 ....*....|....*....|....*....|....
gi 488473090   1 MSTSPLVIAIDGPSGSGKSSTSRGVANRLGLARL 34
Cdd:COG2074    2 RMKRPRIILIGGASGVGKSTIAAELARRLGIPRV 35
PRK05480 PRK05480
uridine/cytidine kinase; Provisional
 1-30 6.87e-03

uridine/cytidine kinase; Provisional


Pssm-ID: 235492 [Multi-domain]  Cd Length: 209  Bit Score: 36.29  E-value: 6.87e-03
                         10        20        30
                 ....*....|....*....|....*....|
gi 488473090   1 MSTSPLVIAIDGPSGSGKSSTSRGVANRLG 30
Cdd:PRK05480   2 MMKKPIIIGIAGGSGSGKTTVASTIYEELG 31
aroK PRK00131
shikimate kinase; Reviewed
 1-36 6.93e-03

shikimate kinase; Reviewed


Pssm-ID: 234654 [Multi-domain]  Cd Length: 175  Bit Score: 35.94  E-value: 6.93e-03
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 488473090   1 MSTSPLVIAIdGPSGSGKSSTSRGVANRLGLARLDT 36
Cdd:PRK00131   1 MLKGPNIVLI-GFMGAGKSTIGRLLAKRLGYDFIDT 35
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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