|
Name |
Accession |
Description |
Interval |
E-value |
| mrcB |
PRK09506 |
bifunctional glycosyl transferase/transpeptidase; Reviewed |
1-824 |
0e+00 |
|
bifunctional glycosyl transferase/transpeptidase; Reviewed
Pssm-ID: 236544 [Multi-domain] Cd Length: 830 Bit Score: 1658.75 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 1 MSGDDREPIGRKGKKAQPKAAPKRplrrrrDEDEYEEDYDEEQNDYDDEEePMPRKVA--SRPPRKKRRWLGLLIKLFLI 78
Cdd:PRK09506 1 MAGNDREPIGRKGKPSRPVKQKVS------RRRYRDDDDYDDYDDYEDEE-PMPRKGKgkGRKPRGKRGWLWLLLKLFIV 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 79 GAVALAIYGVYLDSQIRSRIDGKVWQLPAAVYGRMVNLEPGMSYSKKEMIALLEGMQYRQVSRMTRPGEFTVQNDSIDIL 158
Cdd:PRK09506 74 FAVLIAIYGVYLDQKIRSRIDGKVWQLPAAVYGRMVNLEPGMSYSKNEMVKLLEATQYRQVSKMTRPGEFTVQANSIEMI 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 159 RRPFDFPDGKEGQIRARLLFKNDRLAQIQNLDNQRDFGLFRLDPKLITMLQSPNGEQRLFVPRAGFPDLLVDTLLATEDR 238
Cdd:PRK09506 154 RRPFDFPDSKEGQVRARLTFDGDRLATIVNLDNNRQFGFFRLDPRLITMLQSPNGEQRLFVPRSGFPDLLVDTLLATEDR 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 239 HFYEHDGVSPYSIARAVVANLTAGKAVQGGSTLTQQLVKNLFLTNERSLVRKLNEAYMALLMDYRYSKDRILELYLNEVY 318
Cdd:PRK09506 234 HFYEHDGISLYSIGRAVLANLTAGRTVQGGSTLTQQLVKNLFLSNERSLWRKANEAYMALIMDARYSKDRILELYLNEVY 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 319 LGQSGGDQIRGFPLGSLYYFGRPVDELSLDQQAMLVGMVKGASLYNPWRNPKLALERRNLVLRLLQNQGIIDAELYTMLS 398
Cdd:PRK09506 314 LGQSGDDQIRGFPLASLYYFGRPVEELSLDQQALLVGMVKGASLYNPWRNPKLALERRNLVLRLLQQQQIIDQELYDMLS 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 399 ARPLGVQPKGGVITPQPAFMQMVRQELQQKLGNKVNDLSGVKIFTTLDPVSQDAAEKAIEDGVPALRAARNMNDLEAAMV 478
Cdd:PRK09506 394 ARPLGVQPKGGVISPQPAFMQMVRQELQAKLGDKVKDLSGVKIFTTLDPVSQDAAEKAVEEGIPALKKQRKLSDLETAMV 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 479 VVDRFSGEVRAMVGGSQPQFAGFNRAMQARRLVGSLAKPPTYLAALSEPDKYRLNTWLSDQPLSLKLSNGSLWQPKNYDR 558
Cdd:PRK09506 474 VVDRFSGEVRAMVGGSEPQFAGYNRAMQARRSIGSLAKPATYLTALSQPDKYRLNTWIADAPISLRQPNGQVWSPQNDDR 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 559 QFRGQVMLMDALVNSLNIPTVNLGMSVGLDQISATLQRLGIPKSVINPVPAMLLGAIDLTPVEVAQEYQTIASGGNRAPL 638
Cdd:PRK09506 554 RFSGRVMLVDALTRSMNVPTVNLGMALGLPAVTDTWIKLGVPKDQLNPVPAMLLGALNLTPIEVAQAFQTIASGGNRAPL 633
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 639 SAVRSVIAEDGTVLYQSFPQAERMVPAQASYLTLYAMQQGVVRGTSRSLSAKFGKYNLAAKTGTTNDLRDSWFAGIDGKE 718
Cdd:PRK09506 634 SALRSVIAEDGKVLYQSFPQAERAVPAQAAYLTLYTMQQVVQRGTGRQLGAKYPNLHLAGKTGTTNDLVDSWFAGIDGKE 713
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 719 VTIAWIGRDNNGPTKLTGASGALTLYRRYLENQTPLPLILQPPEGISQMNIDSAGNFVCGeGSGMRVIPVWTENPQALCQ 798
Cdd:PRK09506 714 VTITWVGRDNNQPTKLYGASGAMTIYQRYLENQTPTPLNLTPPEDIVDMGVDYDGNFVCG-SGGMRVLPVWTDDPQSLCQ 792
|
810 820 830
....*....|....*....|....*....|....*...
gi 488138150 799 GS-----------TPTQDPT-KPNDDGVADWIKEMFGQ 824
Cdd:PRK09506 793 QSemqqqpsqpqqQPQQQPAeQKDSDGVAGWIKDMFGQ 830
|
|
| PBP_1b |
TIGR02071 |
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) ... |
70-798 |
0e+00 |
|
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of a particular bifunctional transglycosylase/transpeptidase in E. coli and other Proteobacteria, designated penicillin-binding protein 1B. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273952 [Multi-domain] Cd Length: 730 Bit Score: 1349.77 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 70 GLLIKLFLIGAVALAIYGVYLDSQIRSRIDGKVWQLPAAVYGRMVNLEPGMSYSKKEMIALLEGMQYRQVSRMTRPGEFT 149
Cdd:TIGR02071 1 GFLLKLAFTAAVLLAFYGLYLDQQIRSRFDGKVWQLPAAVYARPLNLEPGMSLSKKELLIELDATQYRQVSHVTLPGEYS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 150 VQNDSIDILRRPFDFPDGKEGQIRARLLFKNDRLAQIQNLDNQRDFGLFRLDPKLITMLQSPNGEQRLFVPRAGFPDLLV 229
Cdd:TIGR02071 81 VQNNSIEVIRRPFDFPDGAEPQRRARLTFNGNQLSKIENLDNNKEFGFFRLDPKLIAMLYSPNGEQRLFVPRDQFPELLV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 230 DTLLATEDRHFYEHDGVSPYSIARAVVANLTAGKAVQGGSTLTQQLVKNLFLTNERSLVRKLNEAYMALLMDYRYSKDRI 309
Cdd:TIGR02071 161 DTLLATEDRDFYEHDGISLYSIGRAVWVNLTAGRTVQGGSTLTQQLVKNLFLSNERSLWRKANEAYMALILDARYSKDRI 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 310 LELYLNEVYLGQSGGDQIRGFPLGSLYYFGRPVDELSLDQQAMLVGMVKGASLYNPWRNPKLALERRNLVLRLLQNQGII 389
Cdd:TIGR02071 241 LELYLNEVYLGQSGDDAIHGFPLASQYYFGRPLGELSLDQVALLVGMVKGPSYYNPWRNPDRALERRNLVLRLLQEQKII 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 390 DAELYTMLSARPLGVQPKGGVITPQPAFMQMVRQELQQKLGNKVNDLSGVKIFTTLDPVSQDAAEKAIEDGVPALRAARN 469
Cdd:TIGR02071 321 DDEEYDMLSARPLGVQKKGGIISRQPAFLQLVRRELRQKLGDKVKDLSGLRIFTTLDPVSQSAAEQAVQETIPALKKKKK 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 470 MNDLEAAMVVVDRFSGEVRAMVGGSQPQFAGFNRAMQARRLVGSLAKPPTYLAALSEPDKYRLNTWLSDQPLSLKLSNGS 549
Cdd:TIGR02071 401 LPDLEAAMVVTDRFTGEVRAMVGGSDPQFAGFNRALQARRQIGSLVKPAVYLTALSQPDKYRLNTWIEDQPLSIKLSNGQ 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 550 LWQPKNYDRQFRGQVMLMDALVNSLNIPTVNLGMSVGLDQISATLQRLGIPKSVINPVPAMLLGAIDLTPVEVAQEYQTI 629
Cdd:TIGR02071 481 VWSPQNYDRRYSGTVMLYDALAHSLNIPTVNLGMKVGLPKVSQTWNKLGINKDEIPPVPSMLLGAINLTPYEVAQLYQTI 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 630 ASGGNRAPLSAVRSVIAEDGTVLYQSFPQAERMVPAQASYLTLYAMQQGVVRGTSRSLSAKFGKYNLAAKTGTTNDLRDS 709
Cdd:TIGR02071 561 ASGGNRAPLSAVRSVLDEDGKVLYQSDPQAEQAVPSQAAYLTLYAMQQVVQRGTARSLGADFPSLSLAGKTGTTNDNRDS 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 710 WFAGIDGKEVTIAWIGRDNNGPTKLTGASGALTLYRRYLENQTPLPLILQPPEGISQMNIDSAGNFVCGE-GSGMRVIPV 788
Cdd:TIGR02071 641 WFAGIDGKEVTIIWLGRDDNGPTKLTGASGALQVYARYLSYQTPEPLLLVPPEGIDWFGVDPQGNGGCKAnCPGARRLPI 720
|
730
....*....|
gi 488138150 789 WTENPQALCQ 798
Cdd:TIGR02071 721 WTGNPQALCQ 730
|
|
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
183-773 |
0e+00 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 697.82 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 183 LAQIQNLDNQRDFGLFRLDPKLITMLQspnGEQRLFVPRAGFPDLLVDTLLATEDRHFYEHDGVSPYSIARAVVANLTAG 262
Cdd:COG0744 44 PEELEDLALPQTSTIYDRDGTLIATLG---DENREWVPLDQIPPHLKDAVVAIEDRRFYEHGGVDPKGIARALVANLTAG 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 263 KAVQGGSTLTQQLVKNLFLTNERSLVRKLNEAYMALLMDYRYSKDRILELYLNEVYLGQsggdQIRGFPLGSLYYFGRPV 342
Cdd:COG0744 121 GVVQGGSTITQQLVKNLFLSNERTLSRKLKEALLALKLERKYSKDEILELYLNTVYFGR----GAYGIEAAAQYYFGKSA 196
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 343 DELSLDQQAMLVGMVKGASLYNPWRNPKLALERRNLVLRLLQNQGIIDAELYTMLSARPLGVQPKGGVIT--PQPAFMQM 420
Cdd:COG0744 197 SDLTLAEAALLAGLVKAPSYYDPYRNPEAAKERRNLVLDRMVEQGYITQAEADAAKAEPLTLVPPPNGAAagKYPYFVDY 276
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 421 VRQELQQKLGNKVNDLSGVKIFTTLDPVSQDAAEKAIEDGVPalraARNMNDLEAAMVVVDRFSGEVRAMVGGSQPQFAG 500
Cdd:COG0744 277 VRRELEELLGEDDLYRGGLKIYTTLDPKLQKAAEKAVKNVLP----EGKPGGLQAALVVVDPKTGEVLAMVGGRDYGKSQ 352
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 501 FNRAMQARRLVGSLAKPPTYLAALSEPdkYRLNTWLSDQPLSLklsNGSLWQPKNYDRQFRGQVMLMDALVNSLNIPTVN 580
Cdd:COG0744 353 FNRATQAKRQPGSTFKPFVYAAALEQG--YTPATTVDDEPVTF---PGGGWSPKNYDGRYRGPVTLREALANSLNTPAVR 427
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 581 LGMSVGLDQISATLQRLGIPKSvINPVPAMLLGAIDLTPVEVAQEYQTIASGGNRAPLSAVRSVIAEDGTVLYQSFPQAE 660
Cdd:COG0744 428 LAQEVGLDKVVDTARRLGITSP-LDPNPSLALGTSEVSPLEMASAYATFANGGVYVEPHAITKVTDADGKVLYEAKPKCE 506
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 661 RMVPAQASYLTLYAMQQGVVRGTSRslSAKFGKYNLAAKTGTTNDLRDSWFAGIDGKEVTIAWIGRDNNGPTK-LTGASG 739
Cdd:COG0744 507 QVISPEVAYLMTDMLQDVVTSGTGR--AARLPGRPVAGKTGTTNDNRDAWFVGYTPQLVTAVWVGNDDNSPMGyVTGGSL 584
|
570 580 590
....*....|....*....|....*....|....*.
gi 488138150 740 ALTLYRRYLENQTPLPLI--LQPPEGISQMNIDSAG 773
Cdd:COG0744 585 PAPIWRDFMEAALEGLPVedFPKPSGVVRIDEPSPT 620
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
206-384 |
1.45e-76 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 245.89 E-value: 1.45e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 206 TMLQSPNGEQRLFVPRAGFPDLLVDTLLATEDRHFYEHDGVSPYSIARAVVANLTAGKAVQGGSTLTQQLVKNLFLTNER 285
Cdd:pfam00912 3 TLLAELGEENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGRIVQGGSTITQQLAKNLFLTPER 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 286 SLVRKLNEAYMALLMDYRYSKDRILELYLNEVYLGQsggdQIRGFPLGSLYYFGRPVDELSLDQQAMLVGMVKGASLYNP 365
Cdd:pfam00912 83 TLTRKLKEAVLALKLERRYSKDEILEAYLNTVYFGR----GAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRYNP 158
|
170
....*....|....*....
gi 488138150 366 WRNPKLALERRNLVLRLLQ 384
Cdd:pfam00912 159 LRNPERAKRRRNLVLDRMV 177
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| mrcB |
PRK09506 |
bifunctional glycosyl transferase/transpeptidase; Reviewed |
1-824 |
0e+00 |
|
bifunctional glycosyl transferase/transpeptidase; Reviewed
Pssm-ID: 236544 [Multi-domain] Cd Length: 830 Bit Score: 1658.75 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 1 MSGDDREPIGRKGKKAQPKAAPKRplrrrrDEDEYEEDYDEEQNDYDDEEePMPRKVA--SRPPRKKRRWLGLLIKLFLI 78
Cdd:PRK09506 1 MAGNDREPIGRKGKPSRPVKQKVS------RRRYRDDDDYDDYDDYEDEE-PMPRKGKgkGRKPRGKRGWLWLLLKLFIV 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 79 GAVALAIYGVYLDSQIRSRIDGKVWQLPAAVYGRMVNLEPGMSYSKKEMIALLEGMQYRQVSRMTRPGEFTVQNDSIDIL 158
Cdd:PRK09506 74 FAVLIAIYGVYLDQKIRSRIDGKVWQLPAAVYGRMVNLEPGMSYSKNEMVKLLEATQYRQVSKMTRPGEFTVQANSIEMI 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 159 RRPFDFPDGKEGQIRARLLFKNDRLAQIQNLDNQRDFGLFRLDPKLITMLQSPNGEQRLFVPRAGFPDLLVDTLLATEDR 238
Cdd:PRK09506 154 RRPFDFPDSKEGQVRARLTFDGDRLATIVNLDNNRQFGFFRLDPRLITMLQSPNGEQRLFVPRSGFPDLLVDTLLATEDR 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 239 HFYEHDGVSPYSIARAVVANLTAGKAVQGGSTLTQQLVKNLFLTNERSLVRKLNEAYMALLMDYRYSKDRILELYLNEVY 318
Cdd:PRK09506 234 HFYEHDGISLYSIGRAVLANLTAGRTVQGGSTLTQQLVKNLFLSNERSLWRKANEAYMALIMDARYSKDRILELYLNEVY 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 319 LGQSGGDQIRGFPLGSLYYFGRPVDELSLDQQAMLVGMVKGASLYNPWRNPKLALERRNLVLRLLQNQGIIDAELYTMLS 398
Cdd:PRK09506 314 LGQSGDDQIRGFPLASLYYFGRPVEELSLDQQALLVGMVKGASLYNPWRNPKLALERRNLVLRLLQQQQIIDQELYDMLS 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 399 ARPLGVQPKGGVITPQPAFMQMVRQELQQKLGNKVNDLSGVKIFTTLDPVSQDAAEKAIEDGVPALRAARNMNDLEAAMV 478
Cdd:PRK09506 394 ARPLGVQPKGGVISPQPAFMQMVRQELQAKLGDKVKDLSGVKIFTTLDPVSQDAAEKAVEEGIPALKKQRKLSDLETAMV 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 479 VVDRFSGEVRAMVGGSQPQFAGFNRAMQARRLVGSLAKPPTYLAALSEPDKYRLNTWLSDQPLSLKLSNGSLWQPKNYDR 558
Cdd:PRK09506 474 VVDRFSGEVRAMVGGSEPQFAGYNRAMQARRSIGSLAKPATYLTALSQPDKYRLNTWIADAPISLRQPNGQVWSPQNDDR 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 559 QFRGQVMLMDALVNSLNIPTVNLGMSVGLDQISATLQRLGIPKSVINPVPAMLLGAIDLTPVEVAQEYQTIASGGNRAPL 638
Cdd:PRK09506 554 RFSGRVMLVDALTRSMNVPTVNLGMALGLPAVTDTWIKLGVPKDQLNPVPAMLLGALNLTPIEVAQAFQTIASGGNRAPL 633
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 639 SAVRSVIAEDGTVLYQSFPQAERMVPAQASYLTLYAMQQGVVRGTSRSLSAKFGKYNLAAKTGTTNDLRDSWFAGIDGKE 718
Cdd:PRK09506 634 SALRSVIAEDGKVLYQSFPQAERAVPAQAAYLTLYTMQQVVQRGTGRQLGAKYPNLHLAGKTGTTNDLVDSWFAGIDGKE 713
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 719 VTIAWIGRDNNGPTKLTGASGALTLYRRYLENQTPLPLILQPPEGISQMNIDSAGNFVCGeGSGMRVIPVWTENPQALCQ 798
Cdd:PRK09506 714 VTITWVGRDNNQPTKLYGASGAMTIYQRYLENQTPTPLNLTPPEDIVDMGVDYDGNFVCG-SGGMRVLPVWTDDPQSLCQ 792
|
810 820 830
....*....|....*....|....*....|....*...
gi 488138150 799 GS-----------TPTQDPT-KPNDDGVADWIKEMFGQ 824
Cdd:PRK09506 793 QSemqqqpsqpqqQPQQQPAeQKDSDGVAGWIKDMFGQ 830
|
|
| PBP_1b |
TIGR02071 |
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) ... |
70-798 |
0e+00 |
|
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of a particular bifunctional transglycosylase/transpeptidase in E. coli and other Proteobacteria, designated penicillin-binding protein 1B. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273952 [Multi-domain] Cd Length: 730 Bit Score: 1349.77 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 70 GLLIKLFLIGAVALAIYGVYLDSQIRSRIDGKVWQLPAAVYGRMVNLEPGMSYSKKEMIALLEGMQYRQVSRMTRPGEFT 149
Cdd:TIGR02071 1 GFLLKLAFTAAVLLAFYGLYLDQQIRSRFDGKVWQLPAAVYARPLNLEPGMSLSKKELLIELDATQYRQVSHVTLPGEYS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 150 VQNDSIDILRRPFDFPDGKEGQIRARLLFKNDRLAQIQNLDNQRDFGLFRLDPKLITMLQSPNGEQRLFVPRAGFPDLLV 229
Cdd:TIGR02071 81 VQNNSIEVIRRPFDFPDGAEPQRRARLTFNGNQLSKIENLDNNKEFGFFRLDPKLIAMLYSPNGEQRLFVPRDQFPELLV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 230 DTLLATEDRHFYEHDGVSPYSIARAVVANLTAGKAVQGGSTLTQQLVKNLFLTNERSLVRKLNEAYMALLMDYRYSKDRI 309
Cdd:TIGR02071 161 DTLLATEDRDFYEHDGISLYSIGRAVWVNLTAGRTVQGGSTLTQQLVKNLFLSNERSLWRKANEAYMALILDARYSKDRI 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 310 LELYLNEVYLGQSGGDQIRGFPLGSLYYFGRPVDELSLDQQAMLVGMVKGASLYNPWRNPKLALERRNLVLRLLQNQGII 389
Cdd:TIGR02071 241 LELYLNEVYLGQSGDDAIHGFPLASQYYFGRPLGELSLDQVALLVGMVKGPSYYNPWRNPDRALERRNLVLRLLQEQKII 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 390 DAELYTMLSARPLGVQPKGGVITPQPAFMQMVRQELQQKLGNKVNDLSGVKIFTTLDPVSQDAAEKAIEDGVPALRAARN 469
Cdd:TIGR02071 321 DDEEYDMLSARPLGVQKKGGIISRQPAFLQLVRRELRQKLGDKVKDLSGLRIFTTLDPVSQSAAEQAVQETIPALKKKKK 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 470 MNDLEAAMVVVDRFSGEVRAMVGGSQPQFAGFNRAMQARRLVGSLAKPPTYLAALSEPDKYRLNTWLSDQPLSLKLSNGS 549
Cdd:TIGR02071 401 LPDLEAAMVVTDRFTGEVRAMVGGSDPQFAGFNRALQARRQIGSLVKPAVYLTALSQPDKYRLNTWIEDQPLSIKLSNGQ 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 550 LWQPKNYDRQFRGQVMLMDALVNSLNIPTVNLGMSVGLDQISATLQRLGIPKSVINPVPAMLLGAIDLTPVEVAQEYQTI 629
Cdd:TIGR02071 481 VWSPQNYDRRYSGTVMLYDALAHSLNIPTVNLGMKVGLPKVSQTWNKLGINKDEIPPVPSMLLGAINLTPYEVAQLYQTI 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 630 ASGGNRAPLSAVRSVIAEDGTVLYQSFPQAERMVPAQASYLTLYAMQQGVVRGTSRSLSAKFGKYNLAAKTGTTNDLRDS 709
Cdd:TIGR02071 561 ASGGNRAPLSAVRSVLDEDGKVLYQSDPQAEQAVPSQAAYLTLYAMQQVVQRGTARSLGADFPSLSLAGKTGTTNDNRDS 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 710 WFAGIDGKEVTIAWIGRDNNGPTKLTGASGALTLYRRYLENQTPLPLILQPPEGISQMNIDSAGNFVCGE-GSGMRVIPV 788
Cdd:TIGR02071 641 WFAGIDGKEVTIIWLGRDDNGPTKLTGASGALQVYARYLSYQTPEPLLLVPPEGIDWFGVDPQGNGGCKAnCPGARRLPI 720
|
730
....*....|
gi 488138150 789 WTENPQALCQ 798
Cdd:TIGR02071 721 WTGNPQALCQ 730
|
|
| PRK14850 |
PRK14850 |
penicillin-binding protein 1b; Provisional |
62-822 |
0e+00 |
|
penicillin-binding protein 1b; Provisional
Pssm-ID: 237835 [Multi-domain] Cd Length: 764 Bit Score: 1062.53 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 62 PRKKRRWLGLLIKLFLIGAVALAIYGVYLDSQIRSRIDGKVWQLPAAVYGRMVNLEPGMSYSKKEMIALLEGMQYRQVSR 141
Cdd:PRK14850 3 FNFKKYIMRFLIYVFFFVLLLILCYGVYLYVKINRFINGKVWNFPTSIYSRIVNLEPGNSYSQKDVIHLLKSTMYRKVDL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 142 MTRPGEFTVQNDSIDILRRPFDFPDGKEGQIRARLLFKNDRLAQIQNLDNQRDFGLFRLDPKLITMLQSPNGEQRLFVPR 221
Cdd:PRK14850 83 VTLPGEFSVKNNTIELIRRSFDFPDIREDEIHARLYFNKDKLVRIKNIDNNHDFSFLRLDPKLIAMLYSPEGKKRLFIPR 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 222 AGFPDLLVDTLLATEDRHFYEHDGVSPYSIARAVVANLTAGKAVQGGSTLTQQLVKNLFLTNERSLVRKLNEAYMALLMD 301
Cdd:PRK14850 163 NQYPEMLIKTLLAIEDKYFYEHDGIHLSSIGRAFLVNLMSGHTIQGGSTLTQQLVKNLFLTNTRSLWRKINEIYMALILD 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 302 YRYSKDRILELYLNEVYLGQSGGDQIRGFPLGSLYYFGRPVDELSLDQQAMLVGMVKGASLYNPWRNPKLALERRNLVLR 381
Cdd:PRK14850 243 RFYSKDRILELYLNEVYLGQDGNEQIRGFPLASIYYFGRPINELNLDQYALLVGMVKGASLYNPWTNPNLTLKRRNLVLF 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 382 LLQNQGIIDAELYTMLSARPLGVQPKGGVITPQPAFMQMVRQELQQKLGNKVNDLSGVKIFTTLDPVSQDAAEKAIEDGV 461
Cdd:PRK14850 323 LLYKQKVITRKLYKDLCSRPLNVQSKGNIISSHPAFIQLVCEEFHKKIHYPFKNFSGTKIFTTLDYISQNAAEQAVKIGI 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 462 PALRAARNMNDLEAAMVVVDRFSGEVRAMVGGSQPQFAGFNRAMQARRLVGSLAKPPTYLAALSEPDKYRLNTWLSDQPL 541
Cdd:PRK14850 403 PILKRKKRLKDLEVAMVIIDRFSGEVRALIGSSKPEFNGYNRALKARRSIGSLSKPITYLTALSQPEKYHLNTWISDTPI 482
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 542 SLKLSNGSLWQPKNYDRQFRGQVMLMDALVNSLNIPTVNLGMSVGLDQISATLQRLGIPKSVINPVPAMLLGAIDLTPVE 621
Cdd:PRK14850 483 SIKLDNGQYWTPKNNNFSFSGKVMLIDALIHSINIPTVHLSINLGLKKLVDSWILLGISSNYITPLPSISLGAINLTPME 562
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 622 VAQEYQTIASGGNRAPLSAVRSVIAEDGTVLYQSFPQAERMVPAQASYLTLYAMQQGVVRGTSRSLSAKFGKYNLAAKTG 701
Cdd:PRK14850 563 VAQVFQIIGSGGYKSSLSSIRSIISDDNKVLYQNFPQSKHVESSQASYLTLYAMQQVVKSGTAKSLGTIFKEFSLAGKTG 642
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 702 TTNDLRDSWFAGIDGKEVTIAWIGRDNNGPTKLTGASGALTLYRRYLENQTPLPLILQPPEGISQMNIDSAGNFVC--GE 779
Cdd:PRK14850 643 TTNNLVDSWFVGIDGKQVVITWIGRDNNHTTKLYGSSGAMKIYKRYLQYQNPVPLVLKAPNNINMFYINNLGELFCkkGN 722
|
730 740 750 760
....*....|....*....|....*....|....*....|...
gi 488138150 780 GSGMRVIPVWTENPQALCQGSTpTQDPTKPNDDGVADWIKEMF 822
Cdd:PRK14850 723 NQYNRMLPIWSINNKKICNDKL-SERFSIKKKKNFLFWLKNLF 764
|
|
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
183-773 |
0e+00 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 697.82 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 183 LAQIQNLDNQRDFGLFRLDPKLITMLQspnGEQRLFVPRAGFPDLLVDTLLATEDRHFYEHDGVSPYSIARAVVANLTAG 262
Cdd:COG0744 44 PEELEDLALPQTSTIYDRDGTLIATLG---DENREWVPLDQIPPHLKDAVVAIEDRRFYEHGGVDPKGIARALVANLTAG 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 263 KAVQGGSTLTQQLVKNLFLTNERSLVRKLNEAYMALLMDYRYSKDRILELYLNEVYLGQsggdQIRGFPLGSLYYFGRPV 342
Cdd:COG0744 121 GVVQGGSTITQQLVKNLFLSNERTLSRKLKEALLALKLERKYSKDEILELYLNTVYFGR----GAYGIEAAAQYYFGKSA 196
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 343 DELSLDQQAMLVGMVKGASLYNPWRNPKLALERRNLVLRLLQNQGIIDAELYTMLSARPLGVQPKGGVIT--PQPAFMQM 420
Cdd:COG0744 197 SDLTLAEAALLAGLVKAPSYYDPYRNPEAAKERRNLVLDRMVEQGYITQAEADAAKAEPLTLVPPPNGAAagKYPYFVDY 276
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 421 VRQELQQKLGNKVNDLSGVKIFTTLDPVSQDAAEKAIEDGVPalraARNMNDLEAAMVVVDRFSGEVRAMVGGSQPQFAG 500
Cdd:COG0744 277 VRRELEELLGEDDLYRGGLKIYTTLDPKLQKAAEKAVKNVLP----EGKPGGLQAALVVVDPKTGEVLAMVGGRDYGKSQ 352
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 501 FNRAMQARRLVGSLAKPPTYLAALSEPdkYRLNTWLSDQPLSLklsNGSLWQPKNYDRQFRGQVMLMDALVNSLNIPTVN 580
Cdd:COG0744 353 FNRATQAKRQPGSTFKPFVYAAALEQG--YTPATTVDDEPVTF---PGGGWSPKNYDGRYRGPVTLREALANSLNTPAVR 427
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 581 LGMSVGLDQISATLQRLGIPKSvINPVPAMLLGAIDLTPVEVAQEYQTIASGGNRAPLSAVRSVIAEDGTVLYQSFPQAE 660
Cdd:COG0744 428 LAQEVGLDKVVDTARRLGITSP-LDPNPSLALGTSEVSPLEMASAYATFANGGVYVEPHAITKVTDADGKVLYEAKPKCE 506
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 661 RMVPAQASYLTLYAMQQGVVRGTSRslSAKFGKYNLAAKTGTTNDLRDSWFAGIDGKEVTIAWIGRDNNGPTK-LTGASG 739
Cdd:COG0744 507 QVISPEVAYLMTDMLQDVVTSGTGR--AARLPGRPVAGKTGTTNDNRDAWFVGYTPQLVTAVWVGNDDNSPMGyVTGGSL 584
|
570 580 590
....*....|....*....|....*....|....*.
gi 488138150 740 ALTLYRRYLENQTPLPLI--LQPPEGISQMNIDSAG 773
Cdd:COG0744 585 PAPIWRDFMEAALEGLPVedFPKPSGVVRIDEPSPT 620
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
215-749 |
6.13e-163 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 483.69 E-value: 6.13e-163
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 215 QRLFVPRAGFPDLLVDTLLATEDRHFYEHDGVSPYSIARAVVANLTAGKAVQGGSTLTQQLVKNLFLTNERSLVRKLNEA 294
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKGIGRAAVANITSGRVLEGGSTITQQLAKNLYLTNERTITRKIQEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 295 YMALLMDYRYSKDRILELYLNEVYLGQsggdQIRGFPLGSLYYFGRPVDELSLDQQAMLVGMVKGASLYNPWRNPKLALE 374
Cdd:TIGR02074 81 LLALKLEQKLSKDEILELYLNRIYFGN----GAYGIEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPFKNPERAKD 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 375 RRNLVLRLLQNQGIIDAELYTMLSARPLGVQPKGGvITPQ---PAFMQMVRQELQQKLGNKVNDlSGVKIFTTLDPVSQD 451
Cdd:TIGR02074 157 RRNLVLSNMVENGYITAEEAEEAINEPIQLYLQTK-KSEQykaPYFVDYVIQELEEEYGEELYT-GGLKIYTTLDLDAQK 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 452 AAEKAIEDGvpaLRAARNMN--DLEAAMVVVDRFSGEVRAMVGGSQPQFAGFNRAMQARRLVGSLAKPPTYLAALSEpdK 529
Cdd:TIGR02074 235 AAEKVLNTG---LRVAGRRDgdDLQAALVAIDPDTGAVRALVGGRDYGKSQFNRATQAKRQPGSTFKPFVYAAALEK--G 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 530 YRLNTWLSDQPlsLKLSNGSLWQPKNYDRQFRGQVMLMDALVNSLNIPTVNLGMSVGLDQISATLQRLGIpKSVINPVPA 609
Cdd:TIGR02074 310 LTPATIVNDEP--ITYNGNGPWSPKNYGGGYRGNVTLRQALAQSRNIPAVRLLQEVGLDKVVALAKRFGI-TSPLDPVLS 386
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 610 MLLGAIDLTPVEVAQEYQTIASGGNRAPLSAVRSVIAEDGTVLYQSFPQAERMVPAQASYLTLYAMQQGVVRGTSRslSA 689
Cdd:TIGR02074 387 LALGTVEVSPLEMASAYAVFANGGKYVEPHGIRKIVDRDGKVIYENKPKTTQVISPATAYIMTDMLKGVVESGTGR--SA 464
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 488138150 690 KFGKYNLAAKTGTTNDLRDSWFAGIDGKEVTIAWIGRDNNGPTKLTGASG--ALTLYRRYLE 749
Cdd:TIGR02074 465 RLPGRPVAGKTGTTQNWRDAWFVGYTPYYVTAVWVGYDDKKTLGKSGTGGglAAPIWRDFMA 526
|
|
| MrcA |
COG5009 |
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis]; |
202-787 |
6.18e-161 |
|
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 444033 [Multi-domain] Cd Length: 785 Bit Score: 487.36 E-value: 6.18e-161
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 202 PKLITMLQSPNG--------EQRLFVPRAGFPDLLVDTLLATEDRHFYEHDGVSPYSIARAVVANLTAGKAVQGGSTLTQ 273
Cdd:COG5009 44 PPTPSRVYSADGkliaefgeERRIPVPIEEIPPLLINAFLAAEDKRFYEHPGVDPIGIARAAVVNLRTGRRVQGGSTITQ 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 274 QLVKNLFLTNERSLVRKLNEAYMALLMDYRYSKDRILELYLNEVYLGQsggdqiR--GFPLGSLYYFGRPVDELSLDQQA 351
Cdd:COG5009 124 QVAKNFLLSPERTLTRKIKEAILALRIEQELSKDEILELYLNKIYLGH------RayGVAAAAQTYFGKSLDELTLAEAA 197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 352 MLVGMVKGASLYNPWRNPKLALERRNLVLRLLQNQGIIDAELYTMLSARPLGVQPKGGVITPQ-PAFMQMVRQELQQKLG 430
Cdd:COG5009 198 MLAGLPKAPSRYNPIRNPERALERRNYVLGRMLELGYITQAEYEAAKAEPLTARYHGASAEVDaPYFAEMVRRELVERYG 277
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 431 NKVNDLSGVKIFTTLDPVSQDAAEKAIEDGV------------------------PALR--------------------- 465
Cdd:COG5009 278 EDALYTGGLKVYTTLDPRLQEAAEKALRDGLlaydrrhgyrgpeahldlaeedwdEALAevpdvgdlrpavvlevddksa 357
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 466 -------------------AARNMND-------------------------------------LEAAMVVVDRFSGEVRA 489
Cdd:COG5009 358 rvglrdgetgtlpleglkwARPYINDnrrgpapksasdvlkpgdvirvrpvadggwrlrqipeVQGALVALDPHTGAVLA 437
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 490 MVGGSQPQFAGFNRAMQARRLVGSLAKPPTYLAALsepDK-YRLNTWLSDQPLSLKL-SNGSLWQPKNYDRQFRGQVMLM 567
Cdd:COG5009 438 LVGGFDFEQSKFNRATQAKRQPGSSFKPFVYAAAL---DNgYTPATIINDAPIVFDDgGGGGVWRPKNYSGKFYGPTTLR 514
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 568 DALVNSLNIPTVNLGMSVGLDQISATLQRLGIPKSvINPVPAMLLGAIDLTPVEVAQEYQTIASGGNRAPLSAVRSVIAE 647
Cdd:COG5009 515 EALEKSRNLVTVRLLQDVGIDYVIDYAERFGIYSK-LPPNLSLALGSGEVTPLEMARAYAVFANGGYRVEPYLIDRIEDR 593
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 648 DGTVLYQSFPQ---------------------AERMVPAQASYLTLYAMQQGVVRGTSRSLSAkFGKYnLAAKTGTTNDL 706
Cdd:COG5009 594 NGKVIYRADPAracedcdaaewdgaeprlpdpAEQVIDPRTAYQMTSMLRGVVQRGTGRRARA-LGRD-IAGKTGTTNDS 671
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 707 RDSWFAGIDGKEVTIAWIGRDNNGP--TKLTGASGALTLYRRY----LENQTPLPliLQPPEGISQMNIDSagnfvcgeG 780
Cdd:COG5009 672 KDAWFVGFTPDLVAGVWVGFDDPRSlgRGETGGRAALPIWIDFmkaaLKDKPEKP--FPVPEGIVTVRIDP--------K 741
|
....*..
gi 488138150 781 SGMRVIP 787
Cdd:COG5009 742 TGLLASP 748
|
|
| PbpC |
COG4953 |
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope ... |
210-769 |
8.72e-94 |
|
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 443980 [Multi-domain] Cd Length: 773 Bit Score: 311.00 E-value: 8.72e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 210 SPNGEQRLFVPRAGFPDLLVDTLLATEDRHFYEHDGVSPYSIARAVVANLTAGKAVQGGSTLTQQLVKnLFLTNERSLVR 289
Cdd:COG4953 59 AADGQWRLPVPLDEVSPRYLQALLAYEDRRFYYHPGVNPLALLRAAWQNLRSGRIVSGGSTLTMQVAR-LLEPRPRTLSG 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 290 KLNEAYMALLMDYRYSKDRILELYLNEVYLGqsGGdqIRGFPLGSLYYFGRPVDELSLDQQAMLVGMVKGASLYNPWRNP 369
Cdd:COG4953 138 KLRQILRALQLERRYSKDEILELYLNLAPYG--GN--IEGVEAASLAYFGKPPSRLSLAEAALLAVLPQAPSRRRPDRNP 213
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 370 KLALERRNLVLRLLQNQGIIDAELYTMLSARPLGVQPKGGvitPQ--PAFMQMVRQELQQklgnkvndlsGVKIFTTLDP 447
Cdd:COG4953 214 ERARAARDRVLARLAEAGVIDAEEAALALLEPVPARRRPL---PQlaPHLARRLLRQLPG----------GTRIRTTLDA 280
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 448 VSQDAAEKAIEDGVPALRAarnMNDLEAAMVVVDRFSGEVRAMVgGSQPQF----AGFNRAMQARRLVGSLAKPPTYLAA 523
Cdd:COG4953 281 GLQRRLERLVRRYVRRLKQ---NGIHNAAVLVVDNRTGEVLAYV-GSADFFdasrQGQVDMVRALRSPGSTLKPFLYGLA 356
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 524 LSE----PdkyrlNTWLSDQPLSLklsngSLWQPKNYDRQFRGQVMLMDALVNSLNIPTVNLGMSVGLDQISATLQRLGI 599
Cdd:COG4953 357 LDQglihP-----ETLLADVPTSF-----GGYRPENFDGTFQGPVSAREALARSLNIPAVRLLEALGPARFYARLRRAGL 426
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 600 pkSVINPVP-----AMLLGAIDLTPVEVAQEYQTIASGGNRAPLSAVRSviaedgtvlyQSFPQAERMVPAQASYLTLYA 674
Cdd:COG4953 427 --RLLLPPAehyglSLILGGAEVTLEELVGLYAALARGGEARPLRLLAG----------EPASPGRRLLSPGAAWLVRDI 494
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 675 MQQGVVRGTSRSLSAKFGKYNLAAKTGTTNDLRDSWFAGIDGKeVTIA-WIGRDNNGPTK-LTGASGALTLYRR---YLE 749
Cdd:COG4953 495 LSDVPRPDGAFGWRALDSPPPIAWKTGTSYGFRDAWAVGFTGR-YTVGvWVGNPDGTPVPgLTGAEAAAPLLFDifdLLP 573
|
570 580
....*....|....*....|
gi 488138150 750 NQTPlPLILQPPEGISQMNI 769
Cdd:COG4953 574 ASRW-PLPFPPPAGLLRVEV 592
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
206-384 |
1.45e-76 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 245.89 E-value: 1.45e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 206 TMLQSPNGEQRLFVPRAGFPDLLVDTLLATEDRHFYEHDGVSPYSIARAVVANLTAGKAVQGGSTLTQQLVKNLFLTNER 285
Cdd:pfam00912 3 TLLAELGEENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGRIVQGGSTITQQLAKNLFLTPER 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 286 SLVRKLNEAYMALLMDYRYSKDRILELYLNEVYLGQsggdQIRGFPLGSLYYFGRPVDELSLDQQAMLVGMVKGASLYNP 365
Cdd:pfam00912 83 TLTRKLKEAVLALKLERRYSKDEILEAYLNTVYFGR----GAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRYNP 158
|
170
....*....|....*....
gi 488138150 366 WRNPKLALERRNLVLRLLQ 384
Cdd:pfam00912 159 LRNPERAKRRRNLVLDRMV 177
|
|
| mrcA |
PRK11636 |
penicillin-binding protein 1a; Provisional |
213-781 |
2.54e-71 |
|
penicillin-binding protein 1a; Provisional
Pssm-ID: 183248 [Multi-domain] Cd Length: 850 Bit Score: 251.20 E-value: 2.54e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 213 GEQR-LFVPRAGFPDLLVDTLLATEDRHFYEHDGVSPYSIARAVVANLTAGKAVQGGSTLTQQLVKNLFLTNERSLVRKL 291
Cdd:PRK11636 62 GEKRrIPLTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIFRAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKI 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 292 NEAYMALLMDYRYSKDRILELYLNEVYLGQsggdqiRGFPLGSL--YYFGRPVDELSLDQQAMLVGMVKGASLYNPWRNP 369
Cdd:PRK11636 142 KEAFLAIRIEQLLTKDEILELYLNKIYLGY------RAYGVGAAaqVYFGKTVDQLTLSEMAVIAGLPKAPSTFNPLYSM 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 370 KLALERRNLVLRLLQNQGIIDAELYTMLSARPLGVQPKGgvitPQPAF-----MQMVRQELQQKLG-NKVNDlsGVKIFT 443
Cdd:PRK11636 216 DRAVARRNVVLSRMLDEGYITQAQYDQARSEPIVANYHA----PEIAFsapylSEMVRQEMYNRYGeNAYED--GYRVYT 289
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 444 TLDPVSQDAAEKAIEDGV-------------------------------------------PA----------------- 463
Cdd:PRK11636 290 TITRKVQQAAQQAVRNNVldydmrhgyrgpanvlwkvgesawdnkkitdtlkalptygpllPAvvtsanpqeatamladg 369
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 464 ---------LRAAR-------------------------------------NMNDLEAAMVVVDRFSGEVRAMVGGSQPQ 497
Cdd:PRK11636 370 ssvalpmegVRWARpyrsdtqqgptprkvtdvvqtgqqiwvrqvddawwlaQVPDVNSALVSINPQNGAVMALVGGFDFN 449
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 498 FAGFNRAMQARRLVGSLAKPPTYLAALsepDK-YRLNTWLSDQPLS-LKLSNGSLWQPKNYDRQFRGQVMLMDALVNSLN 575
Cdd:PRK11636 450 QSKFNRATQALRQVGSNIKPFLYTAAM---DKgLTLASMLNDVPISrWDAGAGSDWRPKNSPPQYAGPIRLRQGLGQSKN 526
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 576 IPTVNLGMSVGLDQISATLQRLGIPKSVINPVPAMLLGAIDLTPVEVAQEYQTIASGGNRAPLSAVRSVIAEDGTVLYQS 655
Cdd:PRK11636 527 VVMVRAMRAMGVDYAAEYLQRFGFPAQNIVHTESLALGSASFTPMQVARGYAVMANGGFLVDPYFISKIENDQGGVIFEA 606
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 656 --------------------------------------------FPQAERMVPAQA-----------------SYLTLYA 674
Cdd:PRK11636 607 kpkvacpecdipviygdtqksnvlenddvenvatsqeqqnssvpMPQLEQANQALVaqngaqeyaphvintplAFLIKSA 686
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 675 MQQGVV-----RGTSRSLSAKFGKYNLAAKTGTTNDLRDSWFAGIDGKEVTIAWIGRDNN----GPTKLTGA-------- 737
Cdd:PRK11636 687 LNTNIFgepgwMGTGWRAGRDLKRRDIGGKTGTTNSSKDAWFSGYGPGVVTSVWIGFDDHrrdlGRTTASGAikdqisgy 766
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|...
gi 488138150 738 -SGALT-------LYRRYLENQTPLPliLQPPEGISQMNID-SAGNFVCGEGS 781
Cdd:PRK11636 767 eGGAKSaqpawddYMKAALEGVPEQP--LTPPPGIVTVNIDrSTGKLANGGNS 817
|
|
| PRK11240 |
PRK11240 |
penicillin-binding protein 1C; Provisional |
232-731 |
1.32e-35 |
|
penicillin-binding protein 1C; Provisional
Pssm-ID: 183049 [Multi-domain] Cd Length: 772 Bit Score: 144.84 E-value: 1.32e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 232 LLATEDRHFYEHDGVSPYSIARAVVANLTAGKAVQGGSTLTQQlVKNLFLTNERSLVRKLNEAYMALLMDYRYSKDRILE 311
Cdd:PRK11240 78 LINYEDRWFWKHPGVNPFSVARAAWQDLTSGRVISGGSTLTMQ-VARLLDPHPRTFGGKIRQLWRALQLEWHLSKREILT 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 312 LYLNEVYLGQSggdqIRGFPLGSLYYFGRPVDELSLDQQAMLVGMVKGASLYNPWRNPKLALERRNLVLRLLQNQGIIDA 391
Cdd:PRK11240 157 LYLNRAPFGGT----LQGIGAASWAYLGKSPANLSYAEAALLAVLPQAPSRLRPDRWPERAEAARNKVLERMAEQGVWSA 232
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 392 ELYTMLSARPLGVQPKGgviTPQ--PAFMQMVRQELQQKlgnkvndlsgvKIFTTLDPVSQdaaeKAIEDGVPALRaARN 469
Cdd:PRK11240 233 EQVKESREEPVWLAPRQ---MPQlaPLFARMMLGKSKSD-----------KIVTTLDAGLQ----RRLEDLALNWK-GRL 293
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 470 MNDLEAAMVVVDRFSGEVRAMVGG----SQPQFaGFNRAMQARRLVGSLAKPPTYLAALSE----PDkyrlnTWLSDQPL 541
Cdd:PRK11240 294 PPRSSLAMIVVDHTDMAVRGWVGSvdlnDDSRF-GHVDMVNAIRSPGSVLKPFVYGLALDDglihPA-----SLLQDVPR 367
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 542 SLklsngSLWQPKNYDRQFRGQVMLMDALVNSLNIPTVNLGMSVGLDQISATLQRLGIP---KSVINPVPAMLLGAIDLT 618
Cdd:PRK11240 368 RT-----GDYRPGNFDSGFHGPVSMSEALVRSLNLPAVQVLEAYGPKRFAAKLRNVGLPlylPAGAEPNLSLILGGAGAR 442
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 619 PVEVAQEYQTIASGGNRAPLSavrsviaedgtvLYQSFPQAER-MVPAQASYLTlyamqQGVVRGTSRSL--SAKFGKYN 695
Cdd:PRK11240 443 LEDMVAAYSAFARHGKAAKLR------------LQPDDPLLERpLMSPGAAWII-----RRIMADEAQPLpdAALPRVVP 505
|
490 500 510
....*....|....*....|....*....|....*.
gi 488138150 696 LAAKTGTTNDLRDSWFAGIDGKEVTIAWIGRDNNGP 731
Cdd:PRK11240 506 LAWKTGTSYGYRDAWAIGVNARYVIGIWTGRPDGTP 541
|
|
| UB2H |
pfam14814 |
Bifunctional transglycosylase second domain; UB2H is the second domain of the ... |
116-200 |
4.35e-33 |
|
Bifunctional transglycosylase second domain; UB2H is the second domain of the transglycosylases, or penicillin-binding proteins PBP1bs)), the multi-domain membrane proteins essential for cell wall synthesis that are targeted by penicillin antibiotics. The exact function of the UB2H domain is uncertain, but it may act as the binding component of PBP1b with different binding partners, or it may participate in the regulation between DNA repair and/or synthesis and cell wall formation during the bacterial cell cycle.
Pssm-ID: 434234 [Multi-domain] Cd Length: 85 Bit Score: 122.28 E-value: 4.35e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 116 LEPGMSYSKKEMIALLEGMQYRQVSRMTRPGEFTVQNDSIDILRRPFDFPDGKEGQIRARLLFKNDRLAQIQNLDNQRDF 195
Cdd:pfam14814 1 LYPGQALSAAQLEQELKLLGYRKVSNPTRPGEYSVSGNRIELYRRGFDFPDGAEPARRVRLRFAGGRVARLQDLDTGRDL 80
|
....*
gi 488138150 196 GLFRL 200
Cdd:pfam14814 81 ALVRL 85
|
|
| mono_pep_trsgly |
TIGR02070 |
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the ... |
215-388 |
1.34e-30 |
|
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the transglycosylases involved in the late stages of peptidoglycan biosynthesis. Members tend to be small, about 240 amino acids in length, and consist almost entirely of a domain described by pfam00912 for transglycosylases. Species with this protein will have several other transglycosylases as well. All species with this protein are Proteobacteria that produce murein (peptidoglycan). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273951 [Multi-domain] Cd Length: 224 Bit Score: 120.26 E-value: 1.34e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 215 QRLFVPRAGFPDLLVDTLLATEDRHFYEHDGVSPYSIARAVVANLTAGKAVQGGSTLTQQLVKNLFLTNERSLVRKLNEA 294
Cdd:TIGR02070 54 QHRWRPYDQISPNLKRAVIASEDAKFVEHHGFDWEAIQDALEKNEKSGKVVRGGSTISQQLAKNLFLWSGRSYLRKGLEA 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 295 YMALLMDYRYSKDRILELYLNEVYLgqsgGDQIRGFPLGSLYYFGRPVDELSLDQQAMLVGMVKGASLYNPWRNPKLALE 374
Cdd:TIGR02070 134 WATWMLETWWSKQRILEVYLNSVEW----GNGVFGAEAAARYYFKRSASNLTRGQAARLAAVLPNPKYYDENRPGPYVRR 209
|
170
....*....|....
gi 488138150 375 RRNLVLRLLQNQGI 388
Cdd:TIGR02070 210 KATWILKQMGYLGL 223
|
|
| PBP1_TM |
pfam14812 |
Transmembrane domain of transglycosylase PBP1 at N-terminal; This is the N-terminal, ... |
1-81 |
1.83e-27 |
|
Transmembrane domain of transglycosylase PBP1 at N-terminal; This is the N-terminal, transmembrane, domain of the transglycosylases ()penicillin-binding proteins), the multi-domain membrane proteins essential for cell wall synthesis that are targeted by penicillin antibiotics. The TM domain is a single helix, several of whose residues lie in close proximity to hydrophobic residues in the TGT domain. The TM helix seems to be necessary for stabilizing the protein-membrane interaction, and the resulting orientation limits the interaction between PBPb1 and lipid II in the membrane in a 2D lateral diffusion fashion.
Pssm-ID: 434232 Cd Length: 85 Bit Score: 106.41 E-value: 1.83e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 1 MSGDDREPIGRKGKKAQPKAAPKRPLRRRRDEDEYEEDYDEEQND--YDDEEEPMPRK-VASRPPRKKRRWLGLLIKLFL 77
Cdd:pfam14812 1 MSGDDREPIGRKGKKSGRKPPRKRASRRRRRDDDYDDEYDDDYDDddDDDEEEPMPRKgKGGRPPRKKRRWLWLLIKLFL 80
|
....
gi 488138150 78 IGAV 81
Cdd:pfam14812 81 VFAV 84
|
|
| PRK13481 |
PRK13481 |
glycosyltransferase; Provisional |
218-364 |
1.09e-25 |
|
glycosyltransferase; Provisional
Pssm-ID: 184078 [Multi-domain] Cd Length: 232 Bit Score: 106.43 E-value: 1.09e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 218 FVPRAGFPDLLVDTLLATEDRHFYEHDGVSPYSIARAVVANLTAGKaVQGGSTLTQQLVKNLFLTNERSLVRKLNEAYMA 297
Cdd:PRK13481 47 FVSADNMPEYVKGAFISMEDERFYKHHGFDLKGTTRALFSTISDRD-VQGGSTITQQVVKNYFYDNERSFTRKVKELFVA 125
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 488138150 298 LLMDYRYSKDRILELYLNEVYLGQsggDQ--IRGfplGSLYYFGRPVD-------ELSLDQQAMLVGMVKGASLYN 364
Cdd:PRK13481 126 HRVEKQYSKNEILSFYLNNIYFGD---NQytLEG---AANHYFGTTVNknsttmsHITVLQSAILASKVNAPSVYN 195
|
|
| FtsI |
COG0768 |
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ... |
430-714 |
3.00e-24 |
|
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain] Cd Length: 568 Bit Score: 107.99 E-value: 3.00e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 430 GNKVNDLSGVK-------IFTTLDPVSQDAAEKAIEDGVPALRAARnmndleAAMVVVDRFSGEVRAMVggSQP-----Q 497
Cdd:COG0768 203 GRVIRDLGEEKppvpgkdLVLTIDSDLQKIAEEALKKAVEEYKAKS------GAVVVMDPKTGEILAMA--SYPsfdpnL 274
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 498 FAG------FNRAMQARRLVGSLAKPPTYLAALSEpDKYRLNTWLSDqPLSLKLSNGSLwqpKNYDRQFRGQVMLMDALV 571
Cdd:COG0768 275 FVGgpdeplRNRAVQGTYEPGSTFKPFTAAAALEE-GVITPDTTFDC-PGYYRVGGRTI---RDWDRGGHGTLTLTEALA 349
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 572 NSLNIPTVNLGMSVGLDQISATLQRLGI-----------------PKSVINPVPAMLLG---AIDLTPVEVAQEYQTIAS 631
Cdd:COG0768 350 KSSNVGFYKLALRLGIDKLYDYLKKFGLgqktgidlpgeasgllpSPKRWYPGETATMSigqGLSVTPLQLAQAYAAIAN 429
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 632 GGNRAPLSAVRSVIAEDGTVLYQSFPQAERMVPAQASYLTLYAMqQGVV---RGTSRslSAKFGKYNLAAKTGT------ 702
Cdd:COG0768 430 GGVLVKPHLVKEIVDPDGEVVKEEPEVLRRVISPETAETVREGM-EGVVnepGGTAR--RAAIPGYRVAGKTGTaqvvdi 506
|
330
....*....|....*..
gi 488138150 703 -----TNDLRDSWFAGI 714
Cdd:COG0768 507 gnggyYKGRHIASFVGF 523
|
|
| Transpeptidase |
pfam00905 |
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss: ... |
478-722 |
2.71e-21 |
|
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.
Pssm-ID: 425939 [Multi-domain] Cd Length: 296 Bit Score: 95.18 E-value: 2.71e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 478 VVVDRFSGEVRAMVGG-----SQPQFAGFNRAMQARRLVGSLAKPPTYLAALSEpDKYRLNTWLSDQPLslKLSNGSLWq 552
Cdd:pfam00905 4 VVLDPKTGEVLAMVGKpsydpNGFIGPLRNRAVTSRYEPGSTFKPFTALAALDN-GVLKPDETIFDWPG--KQQGGKSI- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 553 pKNYDRQFRGQVMLMDALVNSLNIPTVNLGMSVGLDQISATLQRLGIPKSVINPVP--------------AMLLGAIDL- 617
Cdd:pfam00905 80 -GDWNQDQVGIGTLRQALEYSSNWYMQKLAQKLGADKLRSYLKKFGYGNKTGIGLPgenagyltpywlegATASFGIGLt 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 618 -TPVEVAQEYQTIASGGNRAPLSAVRSVIAEDgtvlyQSFPQAERMVPAQASYLTLYAMQQGVVRGTSRSLSAKFGkYNL 696
Cdd:pfam00905 159 iTPLQQAQAYAAIANGGKLVPPHLVKSIEDKV-----DPKVLNKLPISKSTAEKVKDMLRLVVNDGTGTGTAAVPG-YKV 232
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 488138150 697 AAKTGTT-----------NDLRDSWFAGI---DGKEVTIA 722
Cdd:pfam00905 233 AGKTGTAqvagpkgggyyDGAQIGWFVGYapaDNPKYAFA 272
|
|
| UvrB_inter |
pfam17757 |
UvrB interaction domain; This domain is found in the UvrB protein where it interacts with the ... |
114-193 |
1.38e-04 |
|
UvrB interaction domain; This domain is found in the UvrB protein where it interacts with the UvrA protein.
Pssm-ID: 465486 [Multi-domain] Cd Length: 91 Bit Score: 41.23 E-value: 1.38e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488138150 114 VNLEPGMSYSKKEMIALLEGMQYRQVSRMTRPGEFTVQNDSIDIlrrpfdFPDGKEGQIrARLLFKNDRLAQIQNLD--N 191
Cdd:pfam17757 1 LSLKVGQEIDRDELLRKLVELGYERNDIVFERGTFRVRGDIVDI------FPAYSEDEA-IRIEFFGDEIESIREFDplT 73
|
..
gi 488138150 192 QR 193
Cdd:pfam17757 74 GR 75
|
|
| |
