|
Name |
Accession |
Description |
Interval |
E-value |
| PRK15127 |
PRK15127 |
multidrug efflux RND transporter permease subunit AcrB; |
1-1018 |
0e+00 |
|
multidrug efflux RND transporter permease subunit AcrB;
Pssm-ID: 185081 [Multi-domain] Cd Length: 1049 Bit Score: 1668.13 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 1 MANYFIDRPVFAWVLAIIMMLAGGLAIMNLPVAQYPQIAPPTITISATYPGADAQTVEDSVTQVIEQNMNGLDGLMYMSS 80
Cdd:PRK15127 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 81 TSDAAGNASITLTFETGTSPDIAQVQVQNKLQLAMPSLPEAVQQQGISVDKSSSNILMVAAFISDNGSLNQYDIADYVAS 160
Cdd:PRK15127 81 NSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 161 NIKDPLSRTAGVGSVQLFGSEYAMRIWLDPQKLNKYNLVPSDVISQIKVQNNQISGGQLGGMPQAADQQLNASIIVQTRL 240
Cdd:PRK15127 161 NMKDPISRTSGVGDVQLFGSQYAMRIWMNPNELNKFQLTPVDVINAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 241 QTPEEFGKILLKVQQDGSQVLLRDVARVELGAEDYSTVARYNGKPAAGIAIKLATGANALDTSRAVKEELNRLSAYFPAS 320
Cdd:PRK15127 241 TSTEEFGKILLKVNQDGSRVRLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 321 LKTIYPYDTTPFIKISIQEVFKTLVEAIILVFLVMYLFLQNFRATIIPTIAVPVVILGTFAILSAVGFTINTLTMFGMVL 400
Cdd:PRK15127 321 LKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 401 AIGLLVDDAIVVVENVERVIAEDKLPPKEATHKSMGQIQRALVGIAVVLSAVFMPMAFMSGATGEIYRQFSITLISSMLL 480
Cdd:PRK15127 401 AIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 481 SVFVAMSLTPALCATILKAAPEGGHKPN--ALFARFNTLFEKSTQHYTDSTRSLLRCTGRYMVVYLLICAGMAVLFLRTP 558
Cdd:PRK15127 481 SVLVALILTPALCATMLKPIAKGDHGEGkkGFFGWFNRMFEKSTHHYTDSVGNILRSTGRYLVLYLIIVVGMAYLFVRLP 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 559 TSFLPEEDQGVFMTTAQLPSGATMVNTTKVLQQVTDYYLTKEKNNVQSVFTVGGFGFSGQGQNNGLAFISLKPWSERVGE 638
Cdd:PRK15127 561 SSFLPDEDQGVFLTMVQLPAGATQERTQKVLNEVTDYYLTKEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGE 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 639 ENSVTAIIQRAMIALSSINKAVVFPFNLPAVAELGTASGFDMELLDNGNLGHEKLTQARNELLSLAAQSPNQVIGVRPNG 718
Cdd:PRK15127 641 ENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLGEAAKHPDMLVGVRPNG 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 719 LEDTPMFKVNVNAAKAEAMGVALSDINQTISTAFGSSYVNDFLNQGRVKKVYVQAGTPFRMLPDNINQWYVRNASGTMAP 798
Cdd:PRK15127 721 LEDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQMVP 800
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 799 LSAYSSTEWTYGSPRLERYNGIPSMEILGEAAAGKSTGDAMKFMADLVAKLPAGVGYSWTGLSYQEALSSNQAPALYAIS 878
Cdd:PRK15127 801 FSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEELASKLPTGVGYDWTGMSYQERLSGNQAPALYAIS 880
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 879 LVVVFLALAALYESWSIPFSVMLVVPLGVVGALLATDLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAVEMMQKEGKTP 958
Cdd:PRK15127 881 LIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGL 960
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 959 VEAIIEAARMRLRPILMTSLAFILGVLPLVISHGAGSGAQNAVGTGVMGGMFAATVLAIY 1018
Cdd:PRK15127 961 IEATLEAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATVLAIF 1020
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
1-1018 |
0e+00 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 1633.28 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 1 MANYFIDRPVFAWVLAIIMMLAGGLAIMNLPVAQYPQIAPPTITISATYPGADAQTVEDSVTQVIEQNMNGLDGLMYMSS 80
Cdd:TIGR00915 1 MAKFFIDRPIFAWVIAIIIMLAGTLSILSLPVSQYPSIAPPAITVSASYPGASAQTVQDTVTQVIEQNMNGIDGLRYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 81 TSDAAGNASITLTFETGTSPDIAQVQVQNKLQLAMPSLPEAVQQQGISVDKSSSNILMVAAFISDNGSLNQYDIADYVAS 160
Cdd:TIGR00915 81 SSDSDGSMTITLTFEQGTDPDIAQVQVQNKLQLATPLLPQEVQRQGVRVEKASSNFLMVIGLVSDDGSMTKEDLSDYAAS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 161 NIKDPLSRTAGVGSVQLFGSEYAMRIWLDPQKLNKYNLVPSDVISQIKVQNNQISGGQLGGMPQAADQQLNASIIVQTRL 240
Cdd:TIGR00915 161 NMVDPLSRLEGVGDVQLFGSQYAMRIWLDPAKLNSYQLTPADVISAISAQNAQISAGQLGGLPAVPGQQLNATIIAQTRL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 241 QTPEEFGKILLKVQQDGSQVLLRDVARVELGAEDYSTVARYNGKPAAGIAIKLATGANALDTSRAVKEELNRLSAYFPAS 320
Cdd:TIGR00915 241 QTPEQFENILLKVNTDGSQVRLKDVARVELGGENYSISARFNGKPASGLAIKLATGANALDTAKAVKAELAVLEPFFPQG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 321 LKTIYPYDTTPFIKISIQEVFKTLVEAIILVFLVMYLFLQNFRATIIPTIAVPVVILGTFAILSAVGFTINTLTMFGMVL 400
Cdd:TIGR00915 321 MKYVYPYDTTPFVEASIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFAMVL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 401 AIGLLVDDAIVVVENVERVIAEDKLPPKEATHKSMGQIQRALVGIAVVLSAVFMPMAFMSGATGEIYRQFSITLISSMLL 480
Cdd:TIGR00915 401 AIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 481 SVFVAMSLTPALCATILKAAPEGGHKPNA--LFARFNTLFEKSTQHYTDSTRSLLRCTGRYMVVYLLICAGMAVLFLRTP 558
Cdd:TIGR00915 481 SVLVALILTPALCATMLKPIEKGEHHEKKggFFGWFNRMFDSSTHGYENGVGKILRRRGRYLLVYVLLVGGMVFLFVRLP 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 559 TSFLPEEDQGVFMTTAQLPSGATMVNTTKVLQQVTDYYLTKEKNNVQSVFTVGGFGFSGQGQNNGLAFISLKPWSERVGE 638
Cdd:TIGR00915 561 TSFLPDEDQGVFMTIVQLPAGATAERTQAVLAQVTKYLLAKEKANVESVFTVNGFSFAGRGQNMGMAFIRLKDWEERTGK 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 639 ENSVTAIIQRAMIALSSINKAVVFPFNLPAVAELGTASGFDMELLDNGNLGHEKLTQARNELLSLAAQSPnQVIGVRPNG 718
Cdd:TIGR00915 641 ENSVFAIAGRATGHFMQIKDAMVIAFVPPAILELGNATGFDFFLQDRAGLGHEALLQARNQLLGLAAQNP-ALTRVRPNG 719
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 719 LEDTPMFKVNVNAAKAEAMGVALSDINQTISTAFGSSYVNDFLNQGRVKKVYVQAGTPFRMLPDNINQWYVRNASGTMAP 798
Cdd:TIGR00915 720 LEDEPQLKIDIDREKAQALGVSIADINTTLSTAWGSSYVNDFIDRGRVKRVYVQAEEDARMSPEDINKWYVRNASGEMVP 799
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 799 LSAYSSTEWTYGSPRLERYNGIPSMEILGEAAAGKSTGDAMKFMADLVAKLPAGVGYSWTGLSYQEALSSNQAPALYAIS 878
Cdd:TIGR00915 800 FSAFATVRWEYGSPQLERYNGLPSMEILGSAAPGVSTGQAMAAMEAIAQKLPPGFGFSWTGMSYEERLSGSQAPALYALS 879
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 879 LVVVFLALAALYESWSIPFSVMLVVPLGVVGALLATDLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAVEMMQKeGKTP 958
Cdd:TIGR00915 880 LLVVFLCLAALYESWSIPVSVMLVVPLGIIGALLATTLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAKELMAQ-GKSI 958
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 959 VEAIIEAARMRLRPILMTSLAFILGVLPLVISHGAGSGAQNAVGTGVMGGMFAATVLAIY 1018
Cdd:TIGR00915 959 VEAALEAARLRLRPILMTSLAFILGVVPLAISTGAGSGSQHAIGTGVFGGMVTATVLAIF 1018
|
|
| PRK10555 |
PRK10555 |
multidrug efflux RND transporter permease AcrD; |
1-1018 |
0e+00 |
|
multidrug efflux RND transporter permease AcrD;
Pssm-ID: 182544 [Multi-domain] Cd Length: 1037 Bit Score: 1457.73 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 1 MANYFIDRPVFAWVLAIIMMLAGGLAIMNLPVAQYPQIAPPTITISATYPGADAQTVEDSVTQVIEQNMNGLDGLMYMSS 80
Cdd:PRK10555 1 MANFFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRITANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 81 TSDAAGNASITLTFETGTSPDIAQVQVQNKLQLAMPSLPEAVQQQGISVDKS-SSNILMVAaFISDNGSLNQYDIADYVA 159
Cdd:PRK10555 81 QSSGTGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGVTVRKTgDTNILTIA-FVSTDGSMDKQDIADYVA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 160 SNIKDPLSRTAGVGSVQLFGSEYAMRIWLDPQKLNKYNLVPSDVISQIKVQNNQISGGQLGGMPQAADQQLNASIIVQTR 239
Cdd:PRK10555 160 SNIQDPLSRVNGVGDIDAYGSQYSMRIWLDPAKLNSFQMTTKDVTDAIESQNAQIAVGQLGGTPSVDKQALNATINAQSL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 240 LQTPEEFGKILLKVQQDGSQVLLRDVARVELGAEDYSTVARYNGKPAAGIAIKLATGANALDTSRAVKEELNRLSAYFPA 319
Cdd:PRK10555 240 LQTPEQFRDITLRVNQDGSEVTLGDVATVELGAEKYDYLSRFNGKPASGLGVKLASGANEMATAKLVLNRLDELAQYFPH 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 320 SLKTIYPYDTTPFIKISIQEVFKTLVEAIILVFLVMYLFLQNFRATIIPTIAVPVVILGTFAILSAVGFTINTLTMFGMV 399
Cdd:PRK10555 320 GLEYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSINTLTMFAMV 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 400 LAIGLLVDDAIVVVENVERVIAEDKLPPKEATHKSMGQIQRALVGIAVVLSAVFMPMAFMSGATGEIYRQFSITLISSML 479
Cdd:PRK10555 400 LAIGLLVDDAIVVVENVERIMSEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVSAMV 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 480 LSVFVAMSLTPALCATILKAAPEGG-HKPNALFARFNTLFEKSTQHYTDSTRSLLRCTGRYMVVYLLICAGMAVLFLRTP 558
Cdd:PRK10555 480 LSVLVAMILTPALCATLLKPLKKGEhHGQKGFFGWFNRMFNRNAERYEKGVAKILHRSLRWILIYVLLLGGMVFLFLRLP 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 559 TSFLPEEDQGVFMTTAQLPSGATMVNTTKVLQQVTDYYLTKEKNNVQSVFTVGGFGFSGQGQNNGLAFISLKPWSERVGE 638
Cdd:PRK10555 560 TSFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEKVEKYYFTHEKDNVMSVFATVGSGPGGNGQNVARMFIRLKDWDERDSK 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 639 ENSVTAIIQRAMIALSSINKAVVFPFNLPAVAELGTASGFDMELLDNGNLGHEKLTQARNELLSLAAQSPnQVIGVRPNG 718
Cdd:PRK10555 640 TGTSFAIIERATKAFNKIKEARVIASSPPAISGLGSSAGFDMELQDHAGAGHDALMAARNQLLALAAKNP-ELTRVRHNG 718
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 719 LEDTPMFKVNVNAAKAEAMGVALSDINQTISTAFGSSYVNDFLNQGRVKKVYVQAGTPFRMLPDNINQWYVRNASGTMAP 798
Cdd:PRK10555 719 LDDSPQLQIDIDQRKAQALGVSIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINLWYVRNKDGGMVP 798
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 799 LSAYSSTEWTYGSPRLERYNGIPSMEILGEAAAGKSTGDAMKFMADLVAKLPAGVGYSWTGLSYQEALSSNQAPALYAIS 878
Cdd:PRK10555 799 FSAFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMDIMESLVKQLPNGFGLEWTAMSYQERLSGAQAPALYAIS 878
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 879 LVVVFLALAALYESWSIPFSVMLVVPLGVVGALLATDLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAVEMMQKeGKTP 958
Cdd:PRK10555 879 LLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAKNAILIVEFANEMNQK-GHDL 957
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 959 VEAIIEAARMRLRPILMTSLAFILGVLPLVISHGAGSGAQNAVGTGVMGGMFAATVLAIY 1018
Cdd:PRK10555 958 FEATLHASRQRLRPILMTSLAFIFGVLPMATSTGAGSGSQHAVGTGVMGGMISATILAIF 1017
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
1-1018 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 1401.65 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 1 MANYFIDRPVFAWVLAIIMMLAGGLAIMNLPVAQYPQIAPPTITISATYPGADAQTVEDSVTQVIEQNMNGLDGLMYMSS 80
Cdd:pfam00873 1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 81 TSdAAGNASITLTFETGTSPDIAQVQVQNKLQLAMPSLPEAVQQQGISVDKSSSNILMVAAFISDNGSLNQYDIADYVAS 160
Cdd:pfam00873 81 QS-SYGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGVQRPGISVIKTSLGPIMVLAVTSPDGSYTQTDLRDYADT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 161 NIKDPLSRTAGVGSVQLFG-SEYAMRIWLDPQKLNKYNLVPSDVISQIKVQNNQISGGQLggmpqaADQQLNASIIVQTR 239
Cdd:pfam00873 160 NIKPQLSRVPGVGDVQLFGgSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQL------EGQGLQALIRAQGQ 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 240 LQTPEEFGKILLKvQQDGSQVLLRDVARVELGAEDYSTVARYNGKPAAGIAIKLATGANALDTSRAVKEELNRLSAYFPA 319
Cdd:pfam00873 234 LQSAEDFEKIIVK-NQDGSPVRLRDVATVELGSELYRGFATFNGKPAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQ 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 320 SLKTIYPYDTTPFIKISIQEVFKTLVEAIILVFLVMYLFLQNFRATIIPTIAVPVVILGTFAILSAVGFTINTLTMFGMV 399
Cdd:pfam00873 313 GVEIVVVYDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLV 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 400 LAIGLLVDDAIVVVENVERVIAEDKLPPKEATHKSMGQIQRALVGIAVVLSAVFMPMAFMSGATGEIYRQFSITLISSML 479
Cdd:pfam00873 393 LAIGLVVDDAIVVVENIERVLEENGLKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAIL 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 480 LSVFVAMSLTPALCATILKAAPEGGHkpNALFARFNTLFEKSTQHYTDSTRSLLRCTGRYMVVYLLICAGMAVLFLRTPT 559
Cdd:pfam00873 473 LSVLVALTLTPALCATLLKPRREPKH--GGFFRWFNRMFDRLTRGYAKLLAKVLRHTAVVLLVALLLVVGSVWLFVRIPT 550
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 560 SFLPEEDQGVFMTTAQLPSGATMVNTTKVLQQVTDYYltKEKNNVQSVFTVG--GFGFSGQGQNNGLAFISLKPWSERVG 637
Cdd:pfam00873 551 EFLPEEDEGVFVTSAQLPPGVSLDQTQRVMKQVEKIL--KEKPEVESVFAVTgfAFSGDNNGPNSGDAFISLKPWKERPG 628
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 638 EENSVTAIIQRAMIALSSINKAVVFPFNLPAVAELGTASGFDMELLD-NGNLGHEKLTQARNELLSLAAQSPnQVIGVRP 716
Cdd:pfam00873 629 PEKSVQALIERLRKALKQIPGANVFLFQPIQLRGLGTISGFRSDLQVkIFGDDLDALDEARNQILAALAQLP-GLSDVRS 707
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 717 NGLEDTPMFKVNVNAAKAEAMGVALSDINQTISTAFGSSYVNDFLNQGRVKKVYVQAGTPFRMLPDNINQWYVRNASGTM 796
Cdd:pfam00873 708 DGQEDQPQLQVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVRNPYGKM 787
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 797 APLSAYSSTEWTYGSPRLERYNGIPSMEILGEAAAGKSTGDAMKFMADLVAK--LPAGVGYSWTGLSYQEALSSNQAPAL 874
Cdd:pfam00873 788 IPLSAFAKIEWGYGPPSINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAKQvkLPPGYGYTWTGQFEQEQLAGNSLPIL 867
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 875 YAISLVVVFLALAALYESWSIPFSVMLVVPLGVVGALLATDLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAVEMMQKE 954
Cdd:pfam00873 868 IALALLVVFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFANELREQE 947
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 445946987 955 GKTPVEAIIEAARMRLRPILMTSLAFILGVLPLVISHGAGSGAQNAVGTGVMGGMFAATVLAIY 1018
Cdd:pfam00873 948 GKSLEEAILEACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTLL 1011
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
1-1018 |
0e+00 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 1173.73 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 1 MANYFIDRPVFAWVLAIIMMLAGGLAIMNLPVAQYPQIAPPTITISATYPGADAQTVEDSVTQVIEQNMNGLDGLMYMSS 80
Cdd:COG0841 3 LSRFFIRRPVAAIVLSLLILLAGLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEALNGVEGIKYITS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 81 TSdAAGNASITLTFETGTSPDIAQVQVQNKLQLAMPSLPEAVQQQGISVDKSSSNILMVAAFISDNGSLNQydIADYVAS 160
Cdd:COG0841 83 TS-SEGSSSITVEFELGTDIDEALVDVQNAVDRARSDLPEDVEPPGVTKVNPSDFPVMVLALSSDDLDELE--LSDYAER 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 161 NIKDPLSRTAGVGSVQLFGS-EYAMRIWLDPQKLNKYNLVPSDVISQIKVQNNQISGGQLGGmpqaadQQLNASIIVQTR 239
Cdd:COG0841 160 NIKDRLERVPGVGQVQIFGGrEREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIGG------GDREYTVRTNGR 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 240 LQTPEEFGKILLKVQqDGSQVLLRDVARVELGAEDYSTVARYNGKPAAGIAIKLATGANALDTSRAVKEELNRLSAYFPA 319
Cdd:COG0841 234 LKTPEEFENIVIRTN-DGSVVRLGDVARVEDGAEDYRSIARLNGKPAVGLAIQKQPGANALEVADAVRAKLEELQASLPE 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 320 SLKTIYPYDTTPFIKISIQEVFKTLVEAIILVFLVMYLFLQNFRATIIPTIAVPVVILGTFAILSAVGFTINTLTMFGMV 399
Cdd:COG0841 313 GVELTIVYDQSEFIRASIEEVVKTLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFALV 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 400 LAIGLLVDDAIVVVENVERVIaEDKLPPKEATHKSMGQIQRALVGIAVVLSAVFMPMAFMSGATGEIYRQFSITLISSML 479
Cdd:COG0841 393 LAIGIVVDDAIVVVENIERHM-EEGLSPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQFALTVAIALL 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 480 LSVFVAMSLTPALCATILKaaPEGGHKPNALFARFNTLFEKSTQHYTDSTRSLLRCTGRYMVVYLLICAGMAVLFLRTPT 559
Cdd:COG0841 472 ISLFVALTLTPALCARLLK--PHPKGKKGRFFRAFNRGFDRLTRGYGRLLRWALRHRKLTLLVALALLALSVLLFGRLPT 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 560 SFLPEEDQGVFMTTAQLPSGATMVNTTKVLQQVTDYYLTKEknNVQSVFTVGGFGFSGQGQNNGLAFISLKPWSERvgeE 639
Cdd:COG0841 550 EFFPEEDQGQIIVSVQLPPGTSLERTEAVVRQVEEILLEVP--EVESVFSVVGFSGGGSGSNSGTIFVTLKPWDER---D 624
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 640 NSVTAIIQRAMIALSSINKAVVFPFNLPAvAELGTASGFDMELLDNgnlGHEKLTQARNELLSLAAQSPnQVIGVRPNGL 719
Cdd:COG0841 625 RSADEIIARLREKLAKIPGARVFVFQPPA-GGLGSGAPIEVQLQGD---DLEELAAAAEKLLAALRQIP-GLVDVRSDLQ 699
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 720 EDTPMFKVNVNAAKAEAMGVALSDINQTISTAFGSSYVNDFLNQGRVKKVYVQAGTPFRMLPDNINQWYVRNASGTMAPL 799
Cdd:COG0841 700 LGKPELQLDIDREKAAALGVTVADVASTLRAALGGRYVNDFNRGGREYDVRVQAPEEDRNSPEDLENLYVRTPDGEMVPL 779
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 800 SAYSSTEWTYGSPRLERYNGIPSMEILGEAAAGKSTGDAMKFMADLVAK--LPAGVGYSWTGLSYQEALSSNQAPALYAI 877
Cdd:COG0841 780 SSVATIEEGTGPSSINRYNGQRSVTVSANLAPGVSLGEALAAIEELAAElkLPPGVSIEFTGQAEEEQESFSSLGLAFLL 859
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 878 SLVVVFLALAALYESWSIPFSVMLVVPLGVVGALLATDLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAVEmMQKEGKT 957
Cdd:COG0841 860 ALLLVYLVLAAQFESFIQPLIILLTVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAILLVDFANQ-LREEGMS 938
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 445946987 958 PVEAIIEAARMRLRPILMTSLAFILGVLPLVISHGAGSGAQNAVGTGVMGGMFAATVLAIY 1018
Cdd:COG0841 939 LREAILEAARLRLRPILMTSLATILGLLPLALGTGAGAEFRQPLGIAVIGGLLFSTLLTLF 999
|
|
| PRK09577 |
PRK09577 |
multidrug efflux RND transporter permease subunit; |
1-1018 |
0e+00 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169981 [Multi-domain] Cd Length: 1032 Bit Score: 1149.21 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 1 MANYFIDRPVFAWVLAIIMMLAGGLAIMNLPVAQYPQIAPPTITISATYPGADAQTVEDSVTQVIEQNMNGLDGLMYMSS 80
Cdd:PRK09577 1 MARFFIDRPVFAWVISLFIMLGGIFAIRALPVAQYPDIAPPVVSIYATYPGASAQVVEESVTALIEREMNGAPGLLYTSA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 81 TSdAAGNASITLTFETGTSPDIAQVQVQNKLQLAMPSLPEAVQQQGISVDKSSSNILMVAAFISDNGSLNQYDIADYVAS 160
Cdd:PRK09577 81 TS-SAGQASLSLTFKQGVNADLAAVEVQNRLKTVEARLPEPVRRDGIQVEKAADNIQLIVSLTSDDGRLTGVELGEYASA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 161 NIKDPLSRTAGVGSVQLFGSEYAMRIWLDPQKLNKYNLVPSDVISQIKVQNNQISGGQLGGMPQAADQQLNASIIVQTRL 240
Cdd:PRK09577 160 NVLQALRRVEGVGKVQFWGAEYAMRIWPDPVKLAALGLTASDIASAVRAHNARVTIGDIGRSAVPDSAPIAATVFADAPL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 241 QTPEEFGKILLKVQQDGSQVLLRDVARVELGAEDYSTVARYNGKPAAGIAIKLATGANALDTSRAVKEELNRLSAYFPAS 320
Cdd:PRK09577 240 KTPEDFGAIALRARADGSALYLRDVARIEFGGNDYNYPSYVNGKTATGMGIKLAPGSNAVATEKRVRATMDELSRYFPPG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 321 LKTIYPYDTTPFIKISIQEVFKTLVEAIILVFLVMYLFLQNFRATIIPTIAVPVVILGTFAILSAVGFTINTLTMFGMVL 400
Cdd:PRK09577 320 VKYQIPYETSSFVRVSMNKVVTTLIEAGVLVFLVMFLFMQNFRATLIPTLVVPVALLGTFGVMLAAGFSINVLTMFGMVL 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 401 AIGLLVDDAIVVVENVERVIAEDKLPPKEATHKSMGQIQRALVGIAVVLSAVFMPMAFMSGATGEIYRQFSITLISSMLL 480
Cdd:PRK09577 400 AIGILVDDAIVVVENVERLMVEEGLSPYDATVKAMKQISGAIVGITVVLTSVFVPMAFFGGAVGNIYRQFALSLAVSIGF 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 481 SVFVAMSLTPALCATILKAAPEGGHKPNALFARFNTLFEKSTQHYTDSTRSLLRCTGRYMVVYLLICAGMAVLFLRTPTS 560
Cdd:PRK09577 480 SAFLALSLTPALCATLLKPVDGDHHEKRGFFGWFNRFVARSTQRYATRVGAILKRPLRWLVVYGALTAAAALLFTRLPTA 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 561 FLPEEDQGVFMTTAQLPSGATMVNTTKVLQQVTDYYLTKEKnnVQSVFTVGGFGFSGQGQNNGLAFISLKPWSERVGEEN 640
Cdd:PRK09577 560 FLPDEDQGNFMVMVIRPQGTPLAETMQSVREVESYLRRHEP--VAYTFALGGFNLYGEGPNGGMIFVTLKDWKERKAARD 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 641 SVTAIIQRAMIALSSINKAVVFPFNLPAVAELGTASGFDMELLDNGNLGHEKLTQARNELLSLAAQSPnQVIGVRPNGLE 720
Cdd:PRK09577 638 HVQAIVARINERFAGTPNTTVFAMNSPALPDLGSTSGFDFRLQDRGGLGYAAFVAAREQLLAEGAKDP-ALTDLMFAGTQ 716
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 721 DTPMFKVNVNAAKAEAMGVALSDINQTISTAFGSSYVNDFLNQGRVKKVYVQAGTPFRMLPDNINQWYVRNASGTMAPLS 800
Cdd:PRK09577 717 DAPQLKLDIDRAKASALGVSMDEINTTLAVMFGSDYIGDFMHGSQVRRVIVQADGRHRLDPDDVKKLRVRNAQGEMVPLA 796
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 801 AYSSTEWTYGSPRLERYNGIPSMEILGEAAAGKSTGDAMKFMADLVAKLPAGVGYSWTGLSYQEALSSNQAPALYAISLV 880
Cdd:PRK09577 797 AFATLHWTLGPPQLTRYNGYPSFTINGSAAPGHSSGEAMAAIERIAATLPAGIGYAWSGQSFEERLSGAQAPMLFALSVL 876
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 881 VVFLALAALYESWSIPFSVMLVVPLGVVGALLATDLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAVEMMQkEGKTPVE 960
Cdd:PRK09577 877 VVFLALAALYESWSIPFAVMLVVPLGVIGAVLGVTLRGMPNDIYFKVGLIATIGLSAKNAILIVEVAKDLVA-QRMSLAD 955
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....*...
gi 445946987 961 AIIEAARMRLRPILMTSLAFILGVLPLVISHGAGSGAQNAVGTGVMGGMFAATVLAIY 1018
Cdd:PRK09577 956 AALEAARLRLRPIVMTSLAFGVGVLPLAFASGAASGAQIAIGTGVLGGVITATVLAVF 1013
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
4-1018 |
0e+00 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 717.57 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 4 YFIDRPVFAWVLAIIMMLAGGLAIMNLPVAQYPQIAPPTITISATYPGADAQTVEDSVTQVIEQNMNGLDGLMYMSSTSd 83
Cdd:NF033617 3 VFIKRPVATLLLSLLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQS- 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 84 AAGNASITLTFETGTSPDIAQVQVQNKLQLAMPSLP-EAVQQQGISVDKSSSNILMVAAFISDngSLNQYDIADYVASNI 162
Cdd:NF033617 82 SLGYSTITLQFRLGTDLDVALSEVQAAINAAQSLLPsEAPDPPVYRKANSADTPIMYIGLTSE--EMPRGQLTDYAERVL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 163 KDPLSRTAGVGSVQLFGSEY-AMRIWLDPQKLNKYNLVPSDVISQIKVQNNQISGGQLGGMPQAADQQLNasiivqTRLQ 241
Cdd:NF033617 160 APKLSQINGVGSVDVSGGQRpAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGAVRGDSVVSTVRAN------DQLK 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 242 TPEEFGKILLKVQQDGSQVLLRDVARVELGAEDYSTVARYNGKPAAGIAIKLATGANALDTSRAVKEELNRLSAYFPASL 321
Cdd:NF033617 234 TAEDYEDLVIKYADNGAPVRLGDVATVELGAENVRNRAWANGVPAVVLGINRQPGANPIEVADEIRALLPELQETLPKNI 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 322 KTIYPYDTTPFIKISIQEVFKTLVEAIILVFLVMYLFLQNFRATIIPTIAVPVVILGTFAILSAVGFTINTLTMFGMVLA 401
Cdd:NF033617 314 KVNVLYDRTRFIRASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALVLA 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 402 IGLLVDDAIVVVENVERVIaEDKLPPKEATHKSMGQIQRALVGIAVVLSAVFMPMAFMSGATGEIYRQFSITLISSMLLS 481
Cdd:NF033617 394 IGLVVDDAIVVVENIHRHI-EEGESPLEAALKGAREIGFTVIAMTLTLVAVYLPILFMGGLTGRLFREFAVTLAGAVIIS 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 482 VFVAMSLTPALCATILKAAPegghKPNALFARFNTLFEKSTQHYTDSTRSLLRCTGRYMVVYLLICAGMAVLFLRTPTSF 561
Cdd:NF033617 473 GIVALTLTPMMCSRLLKANE----KPGRFARAVDRFFDGLTARYGRGLKWVLKHRPLTLVVALATLALLPLLYVFIPKEL 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 562 LPEEDQGVFMTTAQLPSGAT---MVNTTKVLQQVTDYYLtkEKNNVQSVFTVggfgFSGQGQNNGLAFISLKPWSERvge 638
Cdd:NF033617 549 APSEDRGVIFGMIQAPQSISldyMSAKMRDVEKILSSDP--EVQSLTSFNGV----GGNPGDNTGFGIINLKPWDER--- 619
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 639 ENSVTAIIQRAMIALSSINKAVVFPFNLPAVAeLGTASGFDMELLDNGNLGHEKLTQARNELLSLAAQSPnQVIGVRPNG 718
Cdd:NF033617 620 DVSAQEIIDRLRPKLAKVPGMDLFLFPLQDLP-GGAGSSLPQYQVTLTPSDYDSLFTWAEKLKEKLRKSP-QFADVDSDL 697
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 719 LEDTPMFKVNVNAAKAEAMGVALSDINQTISTAFGSSYVNDFLNQGRVKKVYVQAGTPFRMLPDNINQWYVRNASGTMAP 798
Cdd:NF033617 698 QDKGPELNVDIDRDKAARLGISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIYVRSNDGKLVP 777
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 799 LSAYSSTEWTYGSPRLERYNGIPSMEILGEAAAGKSTGDAMKFMADLVA-KLPAGVGYSWTGLSYQEALSSNQAPALYAI 877
Cdd:NF033617 778 LSTLAKIEERAAPLSLNHFNQFNSATLSFNLAPGVSLGEAIEALDQAAKeLLPSGISGSFQGAARAFQEEGSSLLFLFLL 857
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 878 SLVVVFLALAALYESWSIPFSVMLVVPLGVVGALLATDLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAVEMMQKEGKT 957
Cdd:NF033617 858 ALAAIYLVLAIQYESFVDPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEFANELQRHQGLS 937
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 445946987 958 PVEAIIEAARMRLRPILMTSLAFILGVLPLVISHGAGSGAQNAVGTGVMGGMFAATVLAIY 1018
Cdd:NF033617 938 RREAIYQAAALRLRPILMTTLAMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVGTLFTLF 998
|
|
| PRK09579 |
PRK09579 |
multidrug efflux RND transporter permease subunit; |
5-1018 |
1.29e-177 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169983 [Multi-domain] Cd Length: 1017 Bit Score: 545.20 E-value: 1.29e-177
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 5 FIDRPVFAWVLAIIMMLAGGLAIMNLPVAQYPQIAPPTITISATYPGADAQTVEDSVTQVIEQNMNGLDGLMYMSSTSDA 84
Cdd:PRK09579 7 FIRRPVLASVVSLLIVLLGFQAWSKLQIRQYPQMENALITVTTAYPGANAETIQGYITQPLQQSLASAEGIDYMTSVSRQ 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 85 agNAS-ITLTFETGTSPDIAQVQVQNKLQLAMPSLPEAVQQQGISVDKSSSNILMVAAFISDngSLNQYDIADYVASNIK 163
Cdd:PRK09579 87 --NFSiISIYARIGADSDRLFTELLAKANEVKNQLPQDAEDPVLSKEAADASALMYISFYSE--EMSNPQITDYLSRVIQ 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 164 DPLSRTAGVGSVQLFGSE-YAMRIWLDPQKLNKYNLVPSDVISQIKVQNNQISGGQLGGmpqaadQQLNASIIVQTRLQT 242
Cdd:PRK09579 163 PKLATLPGMAEAEILGNQvFAMRLWLDPVKLAGFGLSAGDVTQAVRRYNFLSAAGEVKG------EYVVTSINASTELKS 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 243 PEEFGKILLKVQQDgSQVLLRDVARVELGAEDYSTVARYNGKPAAGIAIKLATGANALDTSRAVKEELNRLSAYFPASLK 322
Cdd:PRK09579 237 AEAFAAIPVKTSGD-SRVLLGDVARVEMGAENYDSISSFDGIPSVYIGIKATPSANPLDVIKEVRAIMPELESQLPPNLK 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 323 TIYPYDTTPFIKISIQEVFKTLVEAIILVFLVMYLFLQNFRATIIPTIAVPVVILGTFAILSAVGFTINTLTMFGMVLAI 402
Cdd:PRK09579 316 VSIAYDATLFIQASIDEVVKTLGEAVLIVIVVVFLFLGALRSVLIPVVTIPLSMIGVLFFMQMMGYSINLLTLLAMVLAI 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 403 GLLVDDAIVVVENVERVIAEDKlPPKEATHKSMGQIQRALVGIAVVLSAVFMPMAFMSGATGEIYRQFSITLISSMLLSV 482
Cdd:PRK09579 396 GLVVDDAIVVVENIHRHIEEGK-SPFDAALEGAREIAMPVVSMTITLAAVYAPIGFLTGLTGALFKEFALTLAGAVIISG 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 483 FVAMSLTPALCATILKAApeggHKPNALFARFNTLFEKSTQHYTDSTRSLLRCTGRYMVVYLLICAGMAVLFLRTPTSFL 562
Cdd:PRK09579 475 IVALTLSPMMCALLLRHE----ENPSGLAHRLDRLFERLKQRYQRALHGTLNTRPVVLVFAVIVLALIPVLLKFTQSELA 550
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 563 PEEDQGV--FMTTAQLPSGATMVNT-----TKVLQQVTDYYLTKEKNNVQSVftvggfgfsgqgqNNGLAFISLKPWSER 635
Cdd:PRK09579 551 PEEDQGIifMMSSSPQPANLDYLNAytdefTPIFKSFPEYYSSFQINGFNGV-------------QSGIGGFLLKPWNER 617
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 636 VGEENSVTAIIQRamiALSSINKAVVFPFNLPAVAelGTASGFDMELLDNGNLGHEKLTQARNELLSLAAQSpNQVIGVR 715
Cdd:PRK09579 618 ERTQMELLPLVQA---KLEEIPGLQIFGFNLPSLP--GTGEGLPFQFVINTANDYESLLQVAQRVKQRAQES-GKFAFLD 691
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 716 PNGLEDTPMFKVNVNAAKAEAMGVALSDINQTISTAFGSSYVNDFLNQGRVKKVYVQAGTPFRMLPDNINQWYVRNASGT 795
Cdd:PRK09579 692 IDLAFDKPEVVVDIDRAKAAQMGVSMQDLGGTLATLLGEGEINRFTIDGRSYKVIAQVERPYRDNPGWLNNYYVKNEQGQ 771
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 796 MAPLSAYSSTEWTYGSPRLERYNGIPSMEILGEAAAgkSTGDAMKFMADLVA-KLPAGVGYSWTGLSYQEALSSNQAPAL 874
Cdd:PRK09579 772 LLPLSTLITLSDRARPRQLNQFQQLNSAIISGFPIV--SMGEAIETVQQIAReEAPEGFAFDYAGASRQYVQEGSALWVT 849
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 875 YAISLVVVFLALAALYESWSIPFSVMLVVPLGVVGALLATDLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAVEMMQKE 954
Cdd:PRK09579 850 FGLALAIIFLVLAAQFESFRDPLVILVTVPLSICGALIPLFLGVSSMNIYTQVGLVTLIGLISKHGILIVEFANQLRHEQ 929
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 445946987 955 GKTPVEAIIEAARMRLRPILMTSLAFILGVLPLVISHGAGSGAQNAVGTGVMGGMFAATVLAIY 1018
Cdd:PRK09579 930 GLSRREAIEEAAAIRLRPVLMTTAAMVFGMVPLILATGAGAVSRFDIGLVIATGMSIGTLFTLF 993
|
|
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
6-1015 |
2.18e-124 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 404.80 E-value: 2.18e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 6 IDRPVFAWVLAIIMMLAGGLAIMNLPVAQYPQIAPPTITISATYPGADAQTVEDSVTQVIEQNMNGLDGLMYMSSTSdAA 85
Cdd:COG3696 10 LRNRLLVLLLTLLLAAAGIYSLRRLPIDAFPDITNVQVQVITEAPGLSPEEVEQQVTYPIETALNGLPGVKEVRSIS-RF 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 86 GNASITLTFETGTSPDIAQVQVQNKLQLAMPSLPEAVQQQGISVDKSSSNILMVAaFISDNGSLNQYD---IADYVasnI 162
Cdd:COG3696 89 GLSVVTVIFEDGTDIYWARQLVLERLQQVREQLPAGVTPELGPISTGLGEIYQYT-LESDPGKYSLMElrtLQDWV---I 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 163 KDPLSRTAGVGSVQLFG---SEYamRIWLDPQKLNKYNLVPSDVISQIKvQNNQISGGqlgGMPQAADQQLnasiIVQT- 238
Cdd:COG3696 165 RPQLRSVPGVAEVNSFGgfvKQY--QVLVDPAKLRAYGLTLDDVIEALE-RNNANVGG---GYIERGGQEY----LVRGi 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 239 -RLQTPEEFGKILLKVQqDGSQVLLRDVARVELGAEDYSTVARYNGKPAA--GIAIKLaTGANALDTSRAVKEELNRLSA 315
Cdd:COG3696 235 gLIRSLEDIENIVVKTR-NGTPVLLRDVAEVRIGPAPRRGAATLNGEGEVvgGIVLML-KGENALEVIEAVKAKLAELKP 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 316 YFPASLKtIYP-YDTTPFIKISIQEVFKTLVEAIILVFLVMYLFLQNFRATIIPTIAVPVVILGTFAILSAVGFTINTLT 394
Cdd:COG3696 313 SLPEGVK-IVPfYDRSDLIDRAIHTVTKNLLEGALLVILVLFLFLGNLRAALIVALAIPLSLLFAFIVMRLFGISANLMS 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 395 MFGMVLAIGLLVDDAIVVVENVERVIAEDKLPPKEATH-----KSMGQIQRALV-GIAVVLsAVFMPMAFMSGATGEIYR 468
Cdd:COG3696 392 LGGLAIDFGIIVDGAVVMVENILRRLEENRAAGTPRERlevvlEAAREVRRPIFfATLIII-LVFLPIFTLEGVEGKLFR 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 469 QFSITLISSMLLSVFVAMSLTPALCATILKAAPEggHKPNALFARFNTLFEkstqhytdstRSLLRCTGRYMVVY---LL 545
Cdd:COG3696 471 PMALTVIFALLGALLLSLTLVPVLASLLLRGKVP--EKENPLVRWLKRLYR----------PLLRWALRHPKLVLavaLV 538
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 546 ICAGMAVLFLRTPTSFLPEEDQGVFMTTAQLPSGATMVNTTKVLQQVTDyyLTKEKNNVQSVFT-------------Vgg 612
Cdd:COG3696 539 LLVLALALFPRLGSEFLPELDEGDLLVMATLPPGISLEESVELGQQVER--ILKSFPEVESVVSrtgraedatdpmgV-- 614
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 613 fgfsgqgqNNGLAFISLKPWSE-RVGEenSVTAIIQRamialssINKAV-VFPfnlpavaelGTASGFDMELLDNGNlgh 690
Cdd:COG3696 615 --------NMSETFVILKPRSEwRSGR--TKEELIAE-------MREALeQIP---------GVNFNFSQPIQMRVD--- 665
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 691 EKLTQAR------------NELLSLAAQSPNQVIGVRpnGLED--------TPMFKVNVNAAKAEAMGVALSDINQTIST 750
Cdd:COG3696 666 ELLSGVRadvavkifgddlDVLRRLAEQIEAVLKTVP--GAADvqvervtgLPQLDIRIDRDAAARYGLNVADVQDVVET 743
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 751 AFGSSYVNDFLNQGRVKKVYVQAGTPFRMLPDNINQWYVRNASGTMAPLSAYSSTEWTYGSPRLERYNGIPSMEI----- 825
Cdd:COG3696 744 AIGGKAVGQVYEGERRFDIVVRLPEELRDDPEAIRNLPIPTPSGAQVPLSQVADIEVVEGPNQISRENGRRRIVVqanvr 823
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 826 ---LGEAAAgkstgDAMKFMADLVaKLPAGVGYSWTGlSYQEALSSNQAPALY-AISLVVVFLALAALYESWSIPFSVML 901
Cdd:COG3696 824 grdLGSFVA-----EAQAKVAEQV-KLPPGYYIEWGG-QFENLQRATARLAIVvPLALLLIFLLLYLAFGSVRDALLILL 896
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 902 VVPLGVVGALLATDLRGLsndvYFQ----VGLLTTIGLSAKNAILIVEFAVEMMqKEGKTPVEAIIEAARMRLRPILMTS 977
Cdd:COG3696 897 NVPFALIGGVLALWLRGM----PLSvsagVGFIALFGVAVLNGVVLVSYINQLR-AEGLDLREAIIEGALERLRPVLMTA 971
|
1050 1060 1070
....*....|....*....|....*....|....*...
gi 445946987 978 LAFILGVLPLVISHGAGSGAQNAVGTGVMGGMFAATVL 1015
Cdd:COG3696 972 LVAALGLLPMALSTGPGSEVQRPLATVVIGGLITSTLL 1009
|
|
| PRK10503 |
PRK10503 |
MdtB/MuxB family multidrug efflux RND transporter permease subunit; |
5-1018 |
1.13e-121 |
|
MdtB/MuxB family multidrug efflux RND transporter permease subunit;
Pssm-ID: 182501 [Multi-domain] Cd Length: 1040 Bit Score: 397.95 E-value: 1.13e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 5 FIDRPVFAWVLAIIMMLAGGLAIMNLPVAQYPQIAPPTITISATYPGADAQTVEDSVTQVIEQNMNGLDGLMYMSSTSdA 84
Cdd:PRK10503 16 FILRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQS-S 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 85 AGNASITLTFETGTSPDIAQVQVQNKLQLAMPSLPEAVQQQGI--SVDKSSSNILMVAAfISDNGSLNQydIADYVASNI 162
Cdd:PRK10503 95 GGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPVysKVNPADPPIMTLAV-TSTAMPMTQ--VEDMVETRV 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 163 KDPLSRTAGVGSVQLFGSEY-AMRIWLDPQKLNKYNLVPSDVISQIKVQNNQISGGQLGGMPQAADQQLNasiivqTRLQ 241
Cdd:PRK10503 172 AQKISQVSGVGLVTLSGGQRpAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPTRAVTLSAN------DQMQ 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 242 TPEEFGKiLLKVQQDGSQVLLRDVARVELGAEDYSTVARYNGKPAAGIAIKLATGANALDTSRAVKEELNRLSAYFPASL 321
Cdd:PRK10503 246 SAEEYRQ-LIIAYQNGAPIRLGDVATVEQGAENSWLGAWANKQQAIVMNVQRQPGANIIATADSIRQMLPQLTESLPKSV 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 322 KTIYPYDTTPFIKISIQEVFKTLVEAIILVFLVMYLFLQNFRATIIPTIAVPVVILGTFAILSAVGFTINTLTMFGMVLA 401
Cdd:PRK10503 325 KVTVLSDRTTNIRASVDDTQFELMLAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIA 404
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 402 IGLLVDDAIVVVENVERVIaEDKLPPKEATHKSMGQIQRALVGIAVVLSAVFMPMAFMSGATGEIYRQFSITLISSMLLS 481
Cdd:PRK10503 405 TGFVVDDAIVVIENISRYI-EKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAVTLAVAILIS 483
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 482 VFVAMSLTPALCATILKAapEGGHKPNALFARFNTLFEKSTQHYTDSTRSLLRCTGRYMVVYLLICAGMAVLFLRTPTSF 561
Cdd:PRK10503 484 AVVSLTLTPMMCARMLSQ--ESLRKQNRFSRASERMFDRVIAAYGRGLAKVLNHPWLTLSVALSTLLLTVLLWIFIPKGF 561
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 562 LPEEDQGVFMTTAQLPSGATMVNTTKVLQQVTDYYLtkEKNNVQSVFTVGGFGFSGQGQNNGLAFISLKPWSERvgeENS 641
Cdd:PRK10503 562 FPVQDNGIIQGTLQAPQSSSFANMAQRQRQVADVIL--QDPAVQSLTSFVGVDGTNPSLNSARLQINLKPLDER---DDR 636
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 642 VTAIIQRAMIALSSINKAVVFpfnLPAVAELG-------TASGFDMEL--LDNGNLGHEKLTQARNELLSLAAQSPNQvi 712
Cdd:PRK10503 637 VQKVIARLQTAVAKVPGVDLY---LQPTQDLTidtqvsrTQYQFTLQAtsLDALSTWVPKLMEKLQQLPQLSDVSSDW-- 711
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 713 gvRPNGLEDTpmfkVNVNAAKAEAMGVALSDINQTISTAFGSSYVNDFLNQGRVKKVYVQAGTPFRMLPDNINQWYVRNA 792
Cdd:PRK10503 712 --QDKGLVAY----VNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDTIRLTSS 785
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 793 SGTMAPLSAYSSTEWTYGSPRLERYNGIPSMEILGEAAAGKSTGDAMKFM--ADLVAKLPAGVGYSWTG--LSYQEALSS 868
Cdd:PRK10503 786 DGGVVPLSSIATIEQRFGPLSINHLDQFPSTTISFNVPDGYSLGDAVQAImdTEKTLNLPADITTQFQGstLAFQSALGS 865
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 869 NQAPALYAIslVVVFLALAALYESWSIPFSVMLVVPLGVVGALLATDLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAV 948
Cdd:PRK10503 866 TVWLIVAAV--VAMYIVLGVLYESFIHPITILSTLPTAGVGALLALMIAGSELDVIAIIGIILLIGIVKKNAIMMIDFAL 943
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 949 EMMQKEGKTPVEAIIEAARMRLRPILMTSLAFILGVLPLVISHGAGSGAQNAVGTGVMGGMFAATVLAIY 1018
Cdd:PRK10503 944 AAEREQGMSPRDAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGICMVGGLIVSQVLTLF 1013
|
|
| PRK10614 |
PRK10614 |
multidrug efflux system subunit MdtC; Provisional |
5-1018 |
1.62e-121 |
|
multidrug efflux system subunit MdtC; Provisional
Pssm-ID: 182589 [Multi-domain] Cd Length: 1025 Bit Score: 397.18 E-value: 1.62e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 5 FIDRPVFAWVLAIIMMLAGGLAIMNLPVAQYPQIAPPTITISATYPGADAQTVEDSVTQVIEQNMNGLDGLMYMSSTSdA 84
Cdd:PRK10614 7 FIYRPVATILLSLAITLCGILGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVNEMTSSS-S 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 85 AGNASITLTFETGTSPDIAQVQVQNKLQLA-------MPSLPEAVQqqgisVDKSSSNIlMVAAFISDNGSlnQYDIADY 157
Cdd:PRK10614 86 LGSTRIILQFDFDRDINGAARDVQAAINAAqsllpsgMPSRPTYRK-----ANPSDAPI-MILTLTSDTYS--QGQLYDF 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 158 VASNIKDPLSRTAGVGSVQLFGSEY-AMRIWLDPQKLNKYNLVPSDVISQIKVQNNQisggqlggMPQAA--DQQLNASI 234
Cdd:PRK10614 158 ASTQLAQTISQIDGVGDVDVGGSSLpAVRVGLNPQALFNQGVSLDDVRQAISNANVR--------RPQGAveDGTHRWQI 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 235 IVQTRLQTPEEFGKILLKVQQdGSQVLLRDVARVELGAEDYSTVARYNGKPAAGIAIKLATGANALDTSRAVKEELNRLS 314
Cdd:PRK10614 230 QTNDELKTAAEYQPLIIHYNN-GAAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDRIRAKLPELR 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 315 AYFPASLKTIYPYDTTPFIKISIQEVFKTLVEAIILVFLVMYLFLQNFRATIIPTIAVPVVILGTFAILSAVGFTINTLT 394
Cdd:PRK10614 309 ETIPAAIDLQIAQDRSPTIRASLEEVEQTLAISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLS 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 395 MFGMVLAIGLLVDDAIVVVENVERVIaEDKLPPKEATHKSMGQIQRALVGIAVVLSAVFMPMAFMSGATGEIYRQFSITL 474
Cdd:PRK10614 389 LMALTIATGFVVDDAIVVLENISRHL-EAGMKPLQAALQGVREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLFREFAVTL 467
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 475 ISSMLLSVFVAMSLTPALCATILKAAPEGGHKPNALFARfntLFEKSTQHYTDSTRSLLRCTGRYMVVYLLICAGMAVLF 554
Cdd:PRK10614 468 SVAIGISLLVSLTLTPMMCAWLLKSSKPREQKRLRGFGR---MLVALQQGYGRSLKWVLNHTRWVGVVLLGTIALNVWLY 544
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 555 LRTPTSFLPEEDQGVFMTTAQLPSGATMVNTTKVLQQVTDyyLTKEKNNVQSV--FTvggfgfSGQGQNNGLAFISLKPW 632
Cdd:PRK10614 545 ISIPKTFFPEQDTGRLMGFIQADQSISFQAMRGKLQDFMK--IIRDDPAVDNVtgFT------GGSRVNSGMMFITLKPL 616
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 633 SERvgeENSVTAIIQRAMIALSSINKAVVFpfnLPAVAEL-----GTASGFDMELL--DNGNLGH--EKLTQARNELLSL 703
Cdd:PRK10614 617 SER---SETAQQVIDRLRVKLAKEPGANLF---LMAVQDIrvggrQSNASYQYTLLsdDLAALREwePKIRKALAALPEL 690
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 704 AAQSPNQvigvRPNGLEdtpmFKVNVNAAKAEAMGVALSDINQTISTAFGS---SYVNDFLNQgrvKKVYVQAGTPFRML 780
Cdd:PRK10614 691 ADVNSDQ----QDKGAE----MALTYDRDTMARLGIDVQAANSLLNNAFGQrqiSTIYQPLNQ---YKVVMEVDPRYTQD 759
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 781 PDNINQWYVRNASGTMAPLSAYSSteWtygsprlERYNGIPSMEILGEAAA---------GKSTGDAMKFMADLVAKL-- 849
Cdd:PRK10614 760 ISALEKMFVINNEGKAIPLSYFAK--W-------QPANAPLSVNHQGLSAAstisfnlptGKSLSDASAAIERAMTQLgv 830
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 850 PAGV--GYSWTGLSYQEALSSNQAPALYAIslVVVFLALAALYESWSIPFSVMLVVPLGVVGALLATDLRGLSNDVYFQV 927
Cdd:PRK10614 831 PSTVrgSFAGTAQVFQETMNSQLILILAAI--ATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALI 908
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 928 GLLTTIGLSAKNAILIVEFAVEMMQKEGKTPVEAIIEAARMRLRPILMTSLAFILGVLPLVISHGAGSGAQNAVGTGVMG 1007
Cdd:PRK10614 909 GIMLLIGIVKKNAIMMVDFALEAQRNGNLTAQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGAELRQPLGITIVG 988
|
1050
....*....|.
gi 445946987 1008 GMFAATVLAIY 1018
Cdd:PRK10614 989 GLVMSQLLTLY 999
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
17-1018 |
1.51e-79 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 281.65 E-value: 1.51e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 17 IIMMLAGGLAIM------NLPVAQYPQIAPPTITISATYPGADAQTVEDSVTQVIEQNMNGLDGLMYMSSTSDAaGNASI 90
Cdd:TIGR00914 15 LVLLATLVMAILgiwsynRLPIDAVPDITNVQVQINTSAPGYSPLEVEQRVTYPIETAMAGLPGLETTRSLSRY-GLSQV 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 91 TLTFETGTSPDIAQVQVQNKLQLAMPSLPEAVQQQGISVDKSSSNILMVA------AFISDNGSLNQYD---IADYVasn 161
Cdd:TIGR00914 94 TVIFKDGTDLYFARQLVNERLQQARDNLPEGVSPEMGPISTGLGEIFLYTveaeegARKKDGGAYTLTDlrtIQDWI--- 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 162 IKDPLSRTAGVGSVQ-LFGSEYAMRIWLDPQKLNKYNLVPSDVISQIKvQNNQISGGqlGGMPQAADQQLnasIIVQTRL 240
Cdd:TIGR00914 171 IRPQLRTVPGVAEVNsIGGYVKQFLVAPDPEKLAAYGLSLADVVNALE-RNNQNVGA--GYIERRGEQYL---VRAPGQV 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 241 QTPEEFGKILLKvQQDGSQVLLRDVARVELGAEDYSTVARYNGKPAAGIAIKLATGANALDTSRAVKEELNRLSAYFPAS 320
Cdd:TIGR00914 245 QSMDDIRNIVIA-TGEGVPIRIRDVARVQIGKELRTGAATENGKEVVLGTVFMLIGENSRTVAQAVGDKLETINKTLPEG 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 321 LKTIYPYDTTPFIKISIQEVFKTLVEAIILVFLVMYLFLQNFRATIIPTIAVPVVILgtFAILSAVGFTINTLTMFGMVL 400
Cdd:TIGR00914 324 VEIVTTYDRSQLVDAAIATVKKNLLEGALLVIVILFLFLGNIRAALIAATVIPLSLL--ITFIGMVFQGISANLMSLGAL 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 401 AIGLLVDDAIVVVENVERVIAEDK------LPPKEATHK---SMGQIQRALVGIAVVLSAVFMPMAFMSGATGEIYRQFS 471
Cdd:TIGR00914 402 DFGLIVDGAVVIVENAHRRLAEAQhhhgrqLTLKERLHEvfaASREVRRPLIFGQLIITLVFLPIFTLTGVEGKMFHPMA 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 472 ITLISSMLLSVFVAMSLTPALCATIL-KAAPEgghKPNALFARFNTLFEKstqhytdstrSLLRCTGRYMVVYLLICAGM 550
Cdd:TIGR00914 482 FTVVLALAGAMILSLTFVPAAVALFIrGKVAE---KENRLMRVLKRRYEP----------LLERVLAWPAVVLGAAAVSI 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 551 AV---LFLRTPTSFLPEEDQGVF-MTTAQLPSgaTMVNTTKVLQQVTDyYLTKEKNNVQSVFT---VGGFGFSGQGQNNG 623
Cdd:TIGR00914 549 VLvvwIASRVGGEFIPSLNEGDLaYQALRIPG--TSLAQSVAMQQTLE-KLIKSFPEVARVFAktgTAEIATDPMPPNAS 625
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 624 LAFISLKP---WSERVGEENSVTAIIQRAMIALSSINKAVVFPFNLpAVAELGTA---------SGFDMELLDngnlghe 691
Cdd:TIGR00914 626 DTYIILKPesqWPEGKKTKEDLIEEIQEATVRIPGNNYEFTQPIQM-RFNELISGvrsdvavkvFGDDLDDLD------- 697
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 692 kltqARNELLSLAAQSPNQVIGVRPNGLEDTPMFKVNVNAAKAEAMGVALSDINQTISTAFGSSYVNDFLNQGRVKKVYV 771
Cdd:TIGR00914 698 ----ATAEKISAVLKGVPGAADVKVEQTTGLPYLTVEIDREKAARYGLTVGDVQDTVATAVGGRMSGETFEGDRRFDIVI 773
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 772 QAGTPFRMLPDNINQWYV-----RNASGTMAPLSAYSSTEWTYGSPRLERYNGIPSMEILGEAAA---GKSTGDAMKFMA 843
Cdd:TIGR00914 774 RLPESLRESPQALRQLPIplplsEDARKQFIPLSDVADLRVSPGPNQISRENGKRRVVVSANVRGrdlGSFVDDAKKAIA 853
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 844 DLVaKLPAGVGYSWTGlSYQEALSSNQAPALYA-ISLVVVFLALAALYESWSIPFSVMLVVPLGVVGALLATDLRGLSND 922
Cdd:TIGR00914 854 EQV-KLPPGYWITWGG-QFEQLQSATKRLQIVVpVTLLLIFVLLYAAFGNVKDALLVFTGIPFALTGGVFALWLRGIPLS 931
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 923 VYFQVGLLTTIGLSAKNAILIVEFAVEMMQkEGKTPVEAIIEAARMRLRPILMTSLAFILGVLPLVISHGAGSGAQNAVG 1002
Cdd:TIGR00914 932 ISAAVGFIALSGVAVLNGLVMISFIRKLLE-EGPSLDEAVYEGALTRVRPVLMTALVASLGFVPMAIATGTGAEVQRPLA 1010
|
1050
....*....|....*.
gi 445946987 1003 TGVMGGMFAATVLAIY 1018
Cdd:TIGR00914 1011 TVVIGGIITATLLTLF 1026
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
286-566 |
2.65e-15 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 80.67 E-value: 2.65e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 286 AAGIAIKLAT-GANALDTSRAVKEELNRLSAYFPASLKTIY----PYDTTPFIKISIQEVFKTLVEAIILVFLVMYLFLQ 360
Cdd:COG1033 161 ATLIVVTLDPdPLSSDLDRKEVVAEIRAIIAKYEDPGVEVYltgfPVLRGDIAEAIQSDLAIFFPLALLLILLLLFLFFR 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 361 NFRATIIPTIAVPVVILGTFAILSAVGFTINTLTMFGMVLAIGLLVDDAIVVVENVERVIAEDKlPPKEATHKSMGQiqr 440
Cdd:COG1033 241 SLRGVLLPLLVVLLAVIWTLGLMGLLGIPLSPLTILVPPLLLAIGIDYGIHLLNRYREERRKGL-DKREALREALRK--- 316
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 441 alVGIAVVLSAV-----FMPMAFMSgatGEIYRQFSITLISSMLLSVFVAMSLTPALCATI--LKAAPEGGHKPNALFAR 513
Cdd:COG1033 317 --LGPPVLLTSLttaigFLSLLFSD---IPPIRDFGIVAAIGVLLAFLTSLTLLPALLSLLprPKPKTRRLKKPPELGRL 391
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 445946987 514 FNTLFEKSTQHYtdstRSLLrctgrymVVYLLICAGMAVLFLRTPTSFLPEED 566
Cdd:COG1033 392 LAKLARFVLRRP----KVIL-------VVALVLAVVSLYGISRLKVEYDFEDY 433
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
301-496 |
4.79e-14 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 76.82 E-value: 4.79e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 301 DTSRAVKEELNR-LSAYFPASLKTIYPYDTTPFIKISIQEVFKTLVE----AIILVFLVMYLFLQNFRATIIPTIAVPVV 375
Cdd:COG1033 563 EEIKALVEEVRAfLAENFPPDGVEVTLTGSAVLFAAINESVIESQIRslllALLLIFLLLLLAFRSLRLGLISLIPNLLP 642
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 376 ILGTFAILSAVGFTINTLTMFGMVLAIGLLVDDAIVVVENVERVIAEDKlPPKEATHKSMGQIQRALVGIAVVLSAVFMP 455
Cdd:COG1033 643 ILLTFGLMGLLGIPLNIATAVVASIALGIGVDYTIHFLSRYREERRKGG-DLEEAIRRALRTTGKAILFTSLTLAAGFGV 721
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 445946987 456 MAFmsgATGEIYRQFSITLISSMLLSVFVAMSLTPALCATI 496
Cdd:COG1033 722 LLF---SSFPPLADFGLLLALGLLVALLAALLLLPALLLLL 759
|
|
| secD |
TIGR01129 |
protein-export membrane protein SecD; Members of this family are highly variable in length ... |
336-492 |
1.78e-07 |
|
protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273456 [Multi-domain] Cd Length: 397 Bit Score: 54.60 E-value: 1.78e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 336 SIQEVFKTLVEAIILVFLVMYLFLQNFraTIIPTIAVPVVILGTFAILSAVGFTINTLTMFGMVLAIGLLVDDAIVVVEN 415
Cdd:TIGR01129 246 SIEAGIKAGLIGLVLVLVFMILYYRLF--GLIAAIALVINIVLILAILSAFGATLTLPGIAGLILTIGMAVDANVLIYER 323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 416 VERVIAEDKlPPKEATHKSMgqiQRALVGI----AVVLSAVFMPMAFMSGATgeiyRQFSITLISSMLLSVFVAMSLTPA 491
Cdd:TIGR01129 324 IKEELRLGK-SVRQAIEAGF---ERAFSTIfdanITTLIAALILYVFGTGPV----KGFAVTLAIGIIASLFTALVFTRL 395
|
.
gi 445946987 492 L 492
Cdd:TIGR01129 396 L 396
|
|
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
158-492 |
5.34e-07 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 53.88 E-value: 5.34e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 158 VASNIKDPLSRTAGVGSVQLF---GSEYaMRIWLDPQKLNKYNLVPSDVISQIKVQnnqisggqLGGMP--QAADQQLNA 232
Cdd:COG3696 690 LAEQIEAVLKTVPGAADVQVErvtGLPQ-LDIRIDRDAAARYGLNVADVQDVVETA--------IGGKAvgQVYEGERRF 760
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 233 SIIVqtRL-----QTPEEFGKILLKVQqDGSQVLLRDVARVELgAEDYSTVARYNGKPAAGIaiklatGANALDTS---- 303
Cdd:COG3696 761 DIVV--RLpeelrDDPEAIRNLPIPTP-SGAQVPLSQVADIEV-VEGPNQISRENGRRRIVV------QANVRGRDlgsf 830
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 304 -----RAVKEELNrlsayFPASlktiypYdttpFIKISIQevFKTLVEA-----------IILVFLVMYLFLQNFRATII 367
Cdd:COG3696 831 vaeaqAKVAEQVK-----LPPG------Y----YIEWGGQ--FENLQRAtarlaivvplaLLLIFLLLYLAFGSVRDALL 893
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 368 PTIAVPVVILG----------TFAILSAVGFtintLTMFGMVlaigllVDDAIVVVENVERVIAEdKLPPKEATHK-SMG 436
Cdd:COG3696 894 ILLNVPFALIGgvlalwlrgmPLSVSAGVGF----IALFGVA------VLNGVVLVSYINQLRAE-GLDLREAIIEgALE 962
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 437 QIqRALVGIAVVLSAVFMPMAFMSGATGEIYRQFSIT----LISSMLLSVFVamslTPAL 492
Cdd:COG3696 963 RL-RPVLMTALVAALGLLPMALSTGPGSEVQRPLATVviggLITSTLLTLLV----LPAL 1017
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
153-507 |
1.90e-06 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 52.07 E-value: 1.90e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 153 DIADYVASNIKDPLSRTAGVGSV---QLFGSEYaMRIWLDPQKLNKYNLVPSDVISQIKVQnnqiSGGQLGGMPQAADQQ 229
Cdd:TIGR00914 694 DDLDATAEKISAVLKGVPGAADVkveQTTGLPY-LTVEIDREKAARYGLTVGDVQDTVATA----VGGRMSGETFEGDRR 768
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 230 LNASI-IVQTRLQTPEEFGK--ILLKVQQDG--SQVLLRDVARVELgAEDYSTVARYNGKPAAGIAIKLA---TGANALD 301
Cdd:TIGR00914 769 FDIVIrLPESLRESPQALRQlpIPLPLSEDArkQFIPLSDVADLRV-SPGPNQISRENGKRRVVVSANVRgrdLGSFVDD 847
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 302 TSRAVKEELNRLSAYFPA-------------SLKTIYPYdttpfikisiqevfktlveAIILVFLVMYLFLQNFRATIIP 368
Cdd:TIGR00914 848 AKKAIAEQVKLPPGYWITwggqfeqlqsatkRLQIVVPV-------------------TLLLIFVLLYAAFGNVKDALLV 908
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 369 TIAVPVVILGTFAILSAVGFTINTLTMFGMVLAIGLLVDDAIVVVENVERVIaEDKLPPKEAT-HKSMGQIqRALVGIAV 447
Cdd:TIGR00914 909 FTGIPFALTGGVFALWLRGIPLSISAAVGFIALSGVAVLNGLVMISFIRKLL-EEGPSLDEAVyEGALTRV-RPVLMTAL 986
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 445946987 448 VLSAVFMPMAFMSGATGEIYRQFSITLISSMLLSVFVAMSLTPALCATILK--AAPEGGHKP 507
Cdd:TIGR00914 987 VASLGFVPMAIATGTGAEVQRPLATVVIGGIITATLLTLFVLPALYRLVHRrrHKGRKEHEP 1048
|
|
| SecD |
COG0342 |
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular ... |
336-492 |
2.56e-06 |
|
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440111 [Multi-domain] Cd Length: 434 Bit Score: 51.27 E-value: 2.56e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 336 SIQEVFKTLVEAIILVFLVMYLFLQNFRatIIPTIAVPVVILGTFAILSAVGFTintLTM---FGMVLAIGLLVDDaivv 412
Cdd:COG0342 269 SIEKGLIAGLIGLLLVALFMLLYYRLPG--LVANIALALNVVLLLGVLSLLGAT---LTLpgiAGIILTIGMAVDA---- 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 413 veNV---ERVIAEDKL--PPKEATHKSmgqIQRALVGIA-----VVLSAVfmPMAFMsgATGEIyRQFSITLISSMLLSV 482
Cdd:COG0342 340 --NVlifERIREELRAgrSLRAAIEAG---FKRAFSTILdanvtTLIAAV--VLFVL--GTGPV-KGFAVTLILGILISM 409
|
170
....*....|
gi 445946987 483 FVAMSLTPAL 492
Cdd:COG0342 410 FTAVPVTRPL 419
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
340-496 |
7.25e-06 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 49.21 E-value: 7.25e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 340 VFKTLVEAIILVFLVMYLFLQNFRATIIPTIAVPV---VILGTFAILS-AVGFTINTLT-MFGMVLAIGLLVDDAIVVVE 414
Cdd:pfam03176 144 LGLIEAVTLVVIFIILLIVYRSVVAALLPLLTVGLslgAAQGLVAILAhILGIGLSTFAlNLLVVLLIAVGTDYALFLVS 223
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 415 NV--ERVIAEDKlppKEATHKSMGQIQRALVGIAVVLSAVFMPMAFmsgATGEIYRQFSITLISSMLLSVFVAMSLTPAL 492
Cdd:pfam03176 224 RYreELRAGEDR---EEAVIRAVRGTGKVVTAAGLTVAIAMLALSF---ARLPVFAQVGPTIAIGVLVDVLAALTLLPAL 297
|
....
gi 445946987 493 CATI 496
Cdd:pfam03176 298 LALL 301
|
|
| PRK13024 |
PRK13024 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
336-489 |
7.92e-06 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 237276 [Multi-domain] Cd Length: 755 Bit Score: 49.84 E-value: 7.92e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 336 SIQEVFKTLVEAIILVFLVMYLFLQnfRATIIPTIAVPVVILGTFAILSAVGFTInTL-TMFGMVLAIGLLVDDAIVVVE 414
Cdd:PRK13024 264 AIDAGIIAGIIGFALIFLFMLVYYG--LPGLIANIALLLYIFLTLGALSSLGAVL-TLpGIAGLVLGIGMAVDANVLIFE 340
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 415 NV-ERVIAEDKLppKEATHKSMgqiQRALVGI----------AVVLsavfmpmaFMSGaTGEIyRQFSITLISSMLLSVF 483
Cdd:PRK13024 341 RIkEELRKGKSL--KKAFKKGF---KNAFSTIldsnittliaAAIL--------FFFG-TGPV-KGFATTLIIGILASLF 405
|
....*.
gi 445946987 484 VAMSLT 489
Cdd:PRK13024 406 TAVFLT 411
|
|
| 2A0604s01 |
TIGR00916 |
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY ... |
336-485 |
9.70e-06 |
|
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY proteins form the protein translocation appartus in prokaryotes. This family is specific for the SecD and SecF proteins. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273336 [Multi-domain] Cd Length: 192 Bit Score: 47.25 E-value: 9.70e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 336 SIQEVFKTLVEAIILVFLVMYLFLQNFRATIIPTIAVPVVILgTFAILSAVGFTINTLTMFGMVLAIGLLVDDAIVVVEN 415
Cdd:TIGR00916 45 LIKAGIIALLIGLVLVLLYMLLRYEWRGAIAAIAALVHDVIL-ILGVLSLFGATLTLPGIAGLLTIIGYSVDDTVVIFDR 123
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 445946987 416 VERVIAEDK-LPPKEATHKSMGQ-IQRALVGIAVVLSAVFMPMAFMSGATgeiyRQFSITLISSMLLSVFVA 485
Cdd:TIGR00916 124 IREELRKYKgRTFREAINLGINQtLSRIIDTNVTTLLAVLALYVFGGGAI----KGFALTLGIGVIAGTYSS 191
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
876-990 |
6.69e-05 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 46.78 E-value: 6.69e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 876 AISLVVVFLALAALYESWSIPFSVMLVVPLGVVGALLATDLRGLSNDVYFQV--GLLTTIGLSakNAI-LIVEFAVEMmq 952
Cdd:COG1033 225 PLALLLILLLLFLFFRSLRGVLLPLLVVLLAVIWTLGLMGLLGIPLSPLTILvpPLLLAIGID--YGIhLLNRYREER-- 300
|
90 100 110
....*....|....*....|....*....|....*...
gi 445946987 953 KEGKTPVEAIIEAARMRLRPILMTSLAFILGVLPLVIS 990
Cdd:COG1033 301 RKGLDKREALREALRKLGPPVLLTSLTTAIGFLSLLFS 338
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
343-492 |
9.48e-05 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 46.37 E-value: 9.48e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 343 TLVEAIILVFLVMYLFlQNFRATIIPTIAVPVVILGTFAILSAVG--FTINTLTMFGMVLAIGllVDDAIVVvenVERVI 420
Cdd:TIGR00921 573 TIAGAILVLMILLAVF-RNPIKAVFPLIAIGSGILWAIGLMGLRGipSFLAMATTISIILGLG--MDYSIHL---AERYF 646
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 445946987 421 AE-DKLPPKEATHKSMGQiqralVGIAVVLSAVFMPMAFMS--GATGEIYRQFSITLISSMLLSVFVAMSLTPAL 492
Cdd:TIGR00921 647 EErKEHGPKEAITHTMER-----TGPGILFSGLTTAGGFLSllLSHFPIMRNFGLVQGIGVLSSLTAALVVFPAL 716
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
347-494 |
1.19e-04 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 45.91 E-value: 1.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 347 AIILVFLVMYLFLQNFRATIIPTIAVPVVILGTFAILSAVG--FTINTLT-MFGMVLAIGLLVDDAIVVV----ENVERv 419
Cdd:COG2409 178 TLPVALVVLLLVFRSLVAALLPLLTAGLAVGVALGLLALLAafTDVSSFApNLLTMLGLGVGIDYALFLVsryrEELRA- 256
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 445946987 420 iaedKLPPKEATHKSMGQIQRALV--GIAVVLSavfmpMAFMSGATGEIYRQFSITLISSMLLSVFVAMSLTPALCA 494
Cdd:COG2409 257 ----GEDREEAVARAVATAGRAVLfsGLTVAIA-----LLGLLLAGLPFLRSMGPAAAIGVAVAVLAALTLLPALLA 324
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
343-496 |
4.83e-04 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 44.06 E-value: 4.83e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 343 TLVEAIILVFLVMYLFLQNFRATIIPTIAVPVVILGTFAILSAVGFTINTLTMFGMVLAIGLLVDDAIVVVENVERVIAE 422
Cdd:TIGR00921 198 TMAISGILVVLVLLLDFKRWWRPLLPLVIILFGVAWVLGIMGWLGIPLYATTLLAVPMLIGVGIDYGIQTLNRYEEERDI 277
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 445946987 423 DKlPPKEATHKSMGQIQRALVGIAVVLSAVFMPMaFMSGAtgEIYRQFSITLISSMLLSVFVAMSLTPALCATI 496
Cdd:TIGR00921 278 GR-AKGEAIVTAVRRTGRAVLIALLTTSAGFAAL-ALSEF--PMVSEFGLGLVAGLITAYLLTLLVLPALLQSI 347
|
|
| HpnN |
TIGR03480 |
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing ... |
293-563 |
3.59e-03 |
|
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing members of this family share the machinery for the biosynthesis of hopanoid lipids. Furthermore, the genes of this family are usually located proximal to other components of this biological process. The proteins appear to be related to the RND family of export proteins, particularly the hydrophobe/amphiphile efflux-3 (HAE3) family represented by TIGR00921.
Pssm-ID: 274598 [Multi-domain] Cd Length: 862 Bit Score: 41.52 E-value: 3.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 293 LATGANALDTSRAVKEELnRLSAYFPASLKTiypydtTPFIKISiQEVFKTLVE--------AIILVFLVMYLFLQNFR- 363
Cdd:TIGR03480 224 LEPAEKAINAIRAAAKDL-RLDEDHGVTVRL------TGEVALS-DEELATVSEgatvagllSFVLVLVLLWLALRSPRl 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 364 -ATIIPTIAVPVVILGTFAILsAVGfTINTLTMFGMVLAIGLLVDDAIVVVENVERVIAEDkLPPKEATHKSMGQIQRAL 442
Cdd:TIGR03480 296 vFAVLVTLIVGLILTAAFATL-AVG-HLNLISVAFAVLFIGLGVDFAIQFSLRYREERFRG-GNHREALSVAARRMGAAL 372
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 443 VGIAVVLSAVFMpmAFMSGAtgeiYRQFS-ITLIS--SMLLSVFVAMSLTPALCaTILKaaPEGGHKPnalfARFNTLfe 519
Cdd:TIGR03480 373 LLAALATAAGFF--AFLPTD----YKGVSeLGIIAgtGMFIALFVTLTVLPALL-RLLR--PPRRRKP----PGYATL-- 437
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 445946987 520 KSTQHYtdstrsLLRCTGRYMVVYLLICAGMAVLFLRTPTSFLP 563
Cdd:TIGR03480 438 APLDAF------LRRHRRPVLGVTLILGIAALALLPQLRFDFNP 475
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
347-507 |
6.32e-03 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 40.48 E-value: 6.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 347 AIILVFLVMYLFLQNFRATIIPTIAVPVVILGTFAILSAVGFTINTLTMFGMVLAIGLLVDDAIVVVENVERVIAEDKlP 426
Cdd:TIGR00915 879 SLLVVFLCLAALYESWSIPVSVMLVVPLGIIGALLATTLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAKELMAQGK-S 957
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 427 PKEATHKSMGQIQRALVGIAVVLSAVFMPMAFMSGATGEIYRQFSITLISSMLLSVFVAMSLTPALCATILKAAPEGGHK 506
Cdd:TIGR00915 958 IVEAALEAARLRLRPILMTSLAFILGVVPLAISTGAGSGSQHAIGTGVFGGMVTATVLAIFFVPLFYVVVRRLFKRKAHE 1037
|
.
gi 445946987 507 P 507
Cdd:TIGR00915 1038 K 1038
|
|
| secD |
PRK05812 |
preprotein translocase subunit SecD; Reviewed |
347-492 |
7.46e-03 |
|
preprotein translocase subunit SecD; Reviewed
Pssm-ID: 235615 [Multi-domain] Cd Length: 462 Bit Score: 40.21 E-value: 7.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 347 AIILVFLVMYlflqnFR-ATIIPTIAVPVVILGTFAILSAVGFTInTLT-MFGMVLAIGLLVDDAIVVVENVERVIAEDK 424
Cdd:PRK05812 308 ALVLLFMILY-----YRlFGLIANIALVANLVLILAVLSLLGATL-TLPgIAGIVLTIGMAVDANVLIFERIREELREGR 381
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 445946987 425 lPPKEATHKSMgqiQRALVGI----------AVVLSAVfmpmafmsgATGEIyRQFSITLISSMLLSVFVAMSLTPAL 492
Cdd:PRK05812 382 -SLRSAIEAGF---KRAFSTIldsnittliaAIILYAL---------GTGPV-KGFAVTLGIGILTSMFTAITVTRAL 445
|
|
| PRK14726 |
PRK14726 |
protein translocase subunit SecDF; |
318-494 |
9.36e-03 |
|
protein translocase subunit SecDF;
Pssm-ID: 237805 [Multi-domain] Cd Length: 855 Bit Score: 40.09 E-value: 9.36e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 318 PASLKTIYPYDTTP-FIKISIQEVFKTLVEAIILVFLVMYLFLQNFraTIIPTIAVPVVILGTFAILSAVGFTINTLTMF 396
Cdd:PRK14726 351 PATLTVVEERTVGPgLGADSIAAGLVAGLIAAILVAALMIGFYGFL--GVIAVIALIVNVVLIIAVLSLLGATLTLPGIA 428
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445946987 397 GMVLAIGLLVDDAIVVvenVERVIAEDKlppkeaTHKSMGQ-----IQRALVGI--AVVLSAVFMPMAFMSGaTGEIyRQ 469
Cdd:PRK14726 429 GIVLTIGMAVDSNVLI---YERIREEEK------TGHSLIQaldrgFSRALATIvdANVTILIAAVILFFLG-SGAV-RG 497
|
170 180
....*....|....*....|....*
gi 445946987 470 FSITLISSMLLSVFVAMSLTPALCA 494
Cdd:PRK14726 498 FAVTLAVGILTTVFTAFTLTRSLVA 522
|
|
| |
