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Conserved domains on  [gi|2569152555|gb|WMI04199|]
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uncharacterized protein (KGM_22016), partial [Taraka hamada]

Protein Classification

ATP-binding protein( domain architecture ID 11440662)

ATP-binding protein with an AAA (ATPases Associated with various cellular Activities) domain may function as an ATPase

Gene Ontology:  GO:0005524|GO:0016887
PubMed:  15037234|18466635|16689629

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RPT1 COG1222
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein ...
 23-281 2.51e-115

ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones];


:

Pssm-ID: 440835 [Multi-domain]  Cd Length: 326  Bit Score: 335.05  E-value: 2.51e-115
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  23 VPDVTWDDVGSLNQVRKDLQLAVLAPVKYPEQLKKLGLSAPSGVLLCGPPGCGKTLLAKAVANEAGVNFISVKGPELLNM 102
Cdd:COG1222    72 SPDVTFDDIGGLDEQIEEIREAVELPLKNPELFRKYGIEPPKGVLLYGPPGTGKTLLAKAVAGELGAPFIRVRGSELVSK 151

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 103 YVGESERAVRTCFRRARNSAPCVIFFDEFDALCPRRSSHDSNGAA-RVVNQLLTEMDGIESREGVFVLAASNRPDIIDPA 181
Cdd:COG1222   152 YIGEGARNVREVFELAREKAPSIIFIDEIDAIAARRTDDGTSGEVqRTVNQLLAELDGFESRGDVLIIAATNRPDLLDPA 231

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 182 VLRPGRLDRIMYVGMPAREDRYDILQKLTKNgtKPqLGPDVDLQVIAGLTEGYTGADLSGLVRAAATNALtqhisngtLE 261
Cdd:COG1222   232 LLRPGRFDRVIEVPLPDEEAREEILKIHLRD--MP-LADDVDLDKLAKLTEGFSGADLKAIVTEAGMFAI--------RE 300

                         250       260
                  ....*....|....*....|
gi 2569152555 262 GDIYVTFDDIRAALEKTKPS 281
Cdd:COG1222   301 GRDTVTMEDLEKAIEKVKKK 320
 
Name Accession Description Interval E-value
RPT1 COG1222
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein ...
 23-281 2.51e-115

ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440835 [Multi-domain]  Cd Length: 326  Bit Score: 335.05  E-value: 2.51e-115
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  23 VPDVTWDDVGSLNQVRKDLQLAVLAPVKYPEQLKKLGLSAPSGVLLCGPPGCGKTLLAKAVANEAGVNFISVKGPELLNM 102
Cdd:COG1222    72 SPDVTFDDIGGLDEQIEEIREAVELPLKNPELFRKYGIEPPKGVLLYGPPGTGKTLLAKAVAGELGAPFIRVRGSELVSK 151

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 103 YVGESERAVRTCFRRARNSAPCVIFFDEFDALCPRRSSHDSNGAA-RVVNQLLTEMDGIESREGVFVLAASNRPDIIDPA 181
Cdd:COG1222   152 YIGEGARNVREVFELAREKAPSIIFIDEIDAIAARRTDDGTSGEVqRTVNQLLAELDGFESRGDVLIIAATNRPDLLDPA 231

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 182 VLRPGRLDRIMYVGMPAREDRYDILQKLTKNgtKPqLGPDVDLQVIAGLTEGYTGADLSGLVRAAATNALtqhisngtLE 261
Cdd:COG1222   232 LLRPGRFDRVIEVPLPDEEAREEILKIHLRD--MP-LADDVDLDKLAKLTEGFSGADLKAIVTEAGMFAI--------RE 300

                         250       260
                  ....*....|....*....|
gi 2569152555 262 GDIYVTFDDIRAALEKTKPS 281
Cdd:COG1222   301 GRDTVTMEDLEKAIEKVKKK 320
CDC48 TIGR01243
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two ...
 2-297 4.33e-109

AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus.


Pssm-ID: 273521 [Multi-domain]  Cd Length: 733  Bit Score: 332.26  E-value: 4.33e-109
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555   2 EDFTKALKTTKPCAVREGIVTVPDVTWDDVGSLNQVRKDLQLAVLAPVKYPEQLKKLGLSAPSGVLLCGPPGCGKTLLAK 81
Cdd:TIGR01243 426 KDFMEALKMVEPSAIREVLVEVPNVRWSDIGGLEEVKQELREAVEWPLKHPEIFEKMGIRPPKGVLLFGPPGTGKTLLAK 505

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  82 AVANEAGVNFISVKGPELLNMYVGESERAVRTCFRRARNSAPCVIFFDEFDALCPRR-SSHDSNGAARVVNQLLTEMDGI 160
Cdd:TIGR01243 506 AVATESGANFIAVRGPEILSKWVGESEKAIREIFRKARQAAPAIIFFDEIDAIAPARgARFDTSVTDRIVNQLLTEMDGI 585

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 161 ESREGVFVLAASNRPDIIDPAVLRPGRLDRIMYVGMPAREDRYDILQKLTKngtKPQLGPDVDLQVIAGLTEGYTGADLS 240
Cdd:TIGR01243 586 QELSNVVVIAATNRPDILDPALLRPGRFDRLILVPPPDEEARKEIFKIHTR---SMPLAEDVDLEELAEMTEGYTGADIE 662

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2569152555 241 GLVRAAATNALTQHISNGTLE----------GDIYVTFDDIRAALEKTKPSVSPKEQLHYEKLRLKY 297
Cdd:TIGR01243 663 AVCREAAMAALRESIGSPAKEklevgeeeflKDLKVEMRHFLEALKKVKPSVSKEDMLRYERLAKEL 729
RecA-like_NVL_r2-like cd19530
second of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL ...
 34-194 2.00e-97

second of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL exists in two forms with N-terminal extensions of different lengths in mammalian cells. NVL has two alternatively spliced isoforms, a short form, NVL1, and a long form, NVL2. NVL2, the major species, is mainly present in the nucleolus, whereas NVL1 is nucleoplasmic. Each has an N-terminal domain, followed by two tandem ATPase domains; this subfamily includes the first of the two ATPase domains. NVL2 is involved in the biogenesis of the 60S ribosome subunit by associating specifically with ribosome protein L5 and modulating the function of DOB1. NVL2 is also required for telomerase assembly and the regulation of telomerase activity, and is involved in pre-rRNA processing. The role of NVL1 is unclear. This RecA-like_NVL_r1-like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410938 [Multi-domain]  Cd Length: 161  Bit Score: 283.61  E-value: 2.00e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  34 LNQVRKDLQLAVLAPVKYPEQLKKLGLSAPSGVLLCGPPGCGKTLLAKAVANEAGVNFISVKGPELLNMYVGESERAVRT 113
Cdd:cd19530     1 LDHVREELTMSILRPIKRPDIYKALGIDLPTGVLLYGPPGCGKTLLAKAVANESGANFISVKGPELLNKYVGESERAVRQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 114 CFRRARNSAPCVIFFDEFDALCPRRSSHDSNGAARVVNQLLTEMDGIESREGVFVLAASNRPDIIDPAVLRPGRLDRIMY 193
Cdd:cd19530    81 VFQRARASAPCVIFFDEVDALVPKRGDGGSWASERVVNQLLTEMDGLEERSNVFVIAATNRPDIIDPAMLRPGRLDKTLY 160


                  .
gi 2569152555 194 V 194
Cdd:cd19530   161 V 161
PRK03992 PRK03992
proteasome-activating nucleotidase; Provisional
 20-277 1.07e-86

proteasome-activating nucleotidase; Provisional


Pssm-ID: 179699 [Multi-domain]  Cd Length: 389  Bit Score: 264.39  E-value: 1.07e-86
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  20 IVTVPDVTWDDVGSLNQVRKDLQLAVLAPVKYPEQLKKLGLSAPSGVLLCGPPGCGKTLLAKAVANEAGVNFISVKGPEL 99
Cdd:PRK03992  122 VIESPNVTYEDIGGLEEQIREVREAVELPLKKPELFEEVGIEPPKGVLLYGPPGTGKTLLAKAVAHETNATFIRVVGSEL 201

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 100 LNMYVGESERAVRTCFRRARNSAPCVIFFDEFDALCPRRsSHDSNGAARVVN----QLLTEMDGIESREGVFVLAASNRP 175
Cdd:PRK03992  202 VQKFIGEGARLVRELFELAREKAPSIIFIDEIDAIAAKR-TDSGTSGDREVQrtlmQLLAEMDGFDPRGNVKIIAATNRI 280

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 176 DIIDPAVLRPGRLDRIMYVGMPAREDRYDILQKLTKngtKPQLGPDVDLQVIAGLTEGYTGADLSGLVRAAATNALTqhi 255
Cdd:PRK03992  281 DILDPAILRPGRFDRIIEVPLPDEEGRLEILKIHTR---KMNLADDVDLEELAELTEGASGADLKAICTEAGMFAIR--- 354

                         250       260
                  ....*....|....*....|..
gi 2569152555 256 sngtlEGDIYVTFDDIRAALEK 277
Cdd:PRK03992  355 -----DDRTEVTMEDFLKAIEK 371
AAA pfam00004
ATPase family associated with various cellular activities (AAA); AAA family proteins often ...
 66-195 2.40e-59

ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.


Pssm-ID: 459627 [Multi-domain]  Cd Length: 130  Bit Score: 185.49  E-value: 2.40e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  66 VLLCGPPGCGKTLLAKAVANEAGVNFISVKGPELLNMYVGESERAVRTCFRRARNSAPCVIFFDEFDALCPRRSSHDSNG 145
Cdd:pfam00004   1 LLLYGPPGTGKTTLAKAVAKELGAPFIEISGSELVSKYVGESEKRLRELFEAAKKLAPCVIFIDEIDALAGSRGSGGDSE 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2569152555 146 AARVVNQLLTEMDGIESREG-VFVLAASNRPDIIDPAVLrpGRLDRIMYVG 195
Cdd:pfam00004  81 SRRVVNQLLTELDGFTSSNSkVIVIAATNRPDKLDPALL--GRFDRIIEFP 129
cell_div_CdvC NF041006
cell division protein CdvC;
24-297 9.80e-57

cell division protein CdvC;


Pssm-ID: 468935 [Multi-domain]  Cd Length: 371  Bit Score: 186.86  E-value: 9.80e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  24 PDVTWDDVGSLNQVRKDLQLAVLAPVKYPEqLKKLGLsaPSGVLLCGPPGCGKTLLAKAVANEAGVNFISVKGPELLNMY 103
Cdd:NF041006   98 PKVTFSDIVGLEDVKEALKEAIVYPSKRPD-LFPLGW--PRGILLYGPPGCGKTMLAAAVANEIDSEFIHVDAASIMSKW 174

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 104 VGESERAVRTCFRRARNSA-----PCVIFFDEFDALCPRRSShDSNGAARVVNQLLTEMDGIE---SREGVFVLAASNRP 175
Cdd:NF041006  175 LGEAEKNVAKIFKKAREKSkeegkPAIIFIDEIDALLGVYSS-EVGGEVRVRNQFLKEMDGLQdksENYHVYVIGATNKP 253

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 176 DIIDPAVLRpgRLDRIMYVGMPAREDRYDILQKLTKngtKPQLGPDVDLQVIAGLTEGYTGADLSGLVRAAATNALTQHI 255
Cdd:NF041006  254 WRLDEPFLR--RFQKRIYIPLPDREQRLELLKYYTS---KIKLENDVDLDELAEMTEGYTASDIRDIVQAAHMRVVKEMF 328

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 2569152555 256 SNGtLEGDIYVTFDDIRAALEKTKPSVSPKEQLHYEKLRLKY 297
Cdd:NF041006  329 EKG-LGEPRPITMEDFKEVLKIRKPSVNQEMLKAYEAWHEKF 369
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 63-195 4.89e-19

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 81.65  E-value: 4.89e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555   63 PSGVLLCGPPGCGKTLLAKAVANEAGVNFISVK-----------------GPELLNMYVGESERAVRTCFRRARNSAPCV 125
Cdd:smart00382   2 GEVILIVGPPGSGKTTLARALARELGPPGGGVIyidgedileevldqlllIIVGGKKASGSGELRLRLALALARKLKPDV 81

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  126 IFFDEFDALCPRRSSHDsngaaRVVNQLLTEMDGIESREGVFVLAASNRPDIIDPAVLRPgRLDRIMYVG 195
Cdd:smart00382  82 LILDEITSLLDAEQEAL-----LLLLEELRLLLLLKSEKNLTVILTTNDEKDLGPALLRR-RFDRRIVLL 145
IS21_help_AAA NF038214
IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was ...
 66-101 4.68e-04

IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was built to hit full-length AAA+ ATPases of IS21 family IS (insertion sequence) elements.


Pssm-ID: 439516  Cd Length: 232  Bit Score: 40.53  E-value: 4.68e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 2569152555  66 VLLCGPPGCGKTLLAKAVANEA-----GVNFISVkgPELLN 101
Cdd:NF038214   93 VLLLGPPGTGKTHLAIALGYAAcrqgyRVRFTTA--ADLVE 131
 
Name Accession Description Interval E-value
RPT1 COG1222
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein ...
 23-281 2.51e-115

ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440835 [Multi-domain]  Cd Length: 326  Bit Score: 335.05  E-value: 2.51e-115
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  23 VPDVTWDDVGSLNQVRKDLQLAVLAPVKYPEQLKKLGLSAPSGVLLCGPPGCGKTLLAKAVANEAGVNFISVKGPELLNM 102
Cdd:COG1222    72 SPDVTFDDIGGLDEQIEEIREAVELPLKNPELFRKYGIEPPKGVLLYGPPGTGKTLLAKAVAGELGAPFIRVRGSELVSK 151

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 103 YVGESERAVRTCFRRARNSAPCVIFFDEFDALCPRRSSHDSNGAA-RVVNQLLTEMDGIESREGVFVLAASNRPDIIDPA 181
Cdd:COG1222   152 YIGEGARNVREVFELAREKAPSIIFIDEIDAIAARRTDDGTSGEVqRTVNQLLAELDGFESRGDVLIIAATNRPDLLDPA 231

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 182 VLRPGRLDRIMYVGMPAREDRYDILQKLTKNgtKPqLGPDVDLQVIAGLTEGYTGADLSGLVRAAATNALtqhisngtLE 261
Cdd:COG1222   232 LLRPGRFDRVIEVPLPDEEAREEILKIHLRD--MP-LADDVDLDKLAKLTEGFSGADLKAIVTEAGMFAI--------RE 300

                         250       260
                  ....*....|....*....|
gi 2569152555 262 GDIYVTFDDIRAALEKTKPS 281
Cdd:COG1222   301 GRDTVTMEDLEKAIEKVKKK 320
CDC48 TIGR01243
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two ...
 2-297 4.33e-109

AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus.


Pssm-ID: 273521 [Multi-domain]  Cd Length: 733  Bit Score: 332.26  E-value: 4.33e-109
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555   2 EDFTKALKTTKPCAVREGIVTVPDVTWDDVGSLNQVRKDLQLAVLAPVKYPEQLKKLGLSAPSGVLLCGPPGCGKTLLAK 81
Cdd:TIGR01243 426 KDFMEALKMVEPSAIREVLVEVPNVRWSDIGGLEEVKQELREAVEWPLKHPEIFEKMGIRPPKGVLLFGPPGTGKTLLAK 505

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  82 AVANEAGVNFISVKGPELLNMYVGESERAVRTCFRRARNSAPCVIFFDEFDALCPRR-SSHDSNGAARVVNQLLTEMDGI 160
Cdd:TIGR01243 506 AVATESGANFIAVRGPEILSKWVGESEKAIREIFRKARQAAPAIIFFDEIDAIAPARgARFDTSVTDRIVNQLLTEMDGI 585

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 161 ESREGVFVLAASNRPDIIDPAVLRPGRLDRIMYVGMPAREDRYDILQKLTKngtKPQLGPDVDLQVIAGLTEGYTGADLS 240
Cdd:TIGR01243 586 QELSNVVVIAATNRPDILDPALLRPGRFDRLILVPPPDEEARKEIFKIHTR---SMPLAEDVDLEELAEMTEGYTGADIE 662

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2569152555 241 GLVRAAATNALTQHISNGTLE----------GDIYVTFDDIRAALEKTKPSVSPKEQLHYEKLRLKY 297
Cdd:TIGR01243 663 AVCREAAMAALRESIGSPAKEklevgeeeflKDLKVEMRHFLEALKKVKPSVSKEDMLRYERLAKEL 729
RecA-like_NVL_r2-like cd19530
second of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL ...
 34-194 2.00e-97

second of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL exists in two forms with N-terminal extensions of different lengths in mammalian cells. NVL has two alternatively spliced isoforms, a short form, NVL1, and a long form, NVL2. NVL2, the major species, is mainly present in the nucleolus, whereas NVL1 is nucleoplasmic. Each has an N-terminal domain, followed by two tandem ATPase domains; this subfamily includes the first of the two ATPase domains. NVL2 is involved in the biogenesis of the 60S ribosome subunit by associating specifically with ribosome protein L5 and modulating the function of DOB1. NVL2 is also required for telomerase assembly and the regulation of telomerase activity, and is involved in pre-rRNA processing. The role of NVL1 is unclear. This RecA-like_NVL_r1-like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410938 [Multi-domain]  Cd Length: 161  Bit Score: 283.61  E-value: 2.00e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  34 LNQVRKDLQLAVLAPVKYPEQLKKLGLSAPSGVLLCGPPGCGKTLLAKAVANEAGVNFISVKGPELLNMYVGESERAVRT 113
Cdd:cd19530     1 LDHVREELTMSILRPIKRPDIYKALGIDLPTGVLLYGPPGCGKTLLAKAVANESGANFISVKGPELLNKYVGESERAVRQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 114 CFRRARNSAPCVIFFDEFDALCPRRSSHDSNGAARVVNQLLTEMDGIESREGVFVLAASNRPDIIDPAVLRPGRLDRIMY 193
Cdd:cd19530    81 VFQRARASAPCVIFFDEVDALVPKRGDGGSWASERVVNQLLTEMDGLEERSNVFVIAATNRPDIIDPAMLRPGRLDKTLY 160


                  .
gi 2569152555 194 V 194
Cdd:cd19530   161 V 161
RecA-like_CDC48_r2-like cd19511
second of two ATPase domains of CDC48/p97, PEX1 and -6, VAT and NVL, and similar ATPase ...
 37-194 1.14e-96

second of two ATPase domains of CDC48/p97, PEX1 and -6, VAT and NVL, and similar ATPase domains; This subfamily includes the second of two ATPase domains of the molecular chaperone CDC48 in yeast and p97 or VCP in metazoans, Peroxisomal biogenesis factor 1 (PEX1) and -6 (PEX6), Valosin-containing protein-like ATPase (VAT), and nuclear VCP-like protein (NVL). This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410919 [Multi-domain]  Cd Length: 159  Bit Score: 281.48  E-value: 1.14e-96
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  37 VRKDLQLAVLAPVKYPEQLKKLGLSAPSGVLLCGPPGCGKTLLAKAVANEAGVNFISVKGPELLNMYVGESERAVRTCFR 116
Cdd:cd19511     1 VKRELKEAVEWPLKHPDAFKRLGIRPPKGVLLYGPPGCGKTLLAKALASEAGLNFISVKGPELFSKYVGESERAVREIFQ 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2569152555 117 RARNSAPCVIFFDEFDALCPRRSSHDSNGAA-RVVNQLLTEMDGIESREGVFVLAASNRPDIIDPAVLRPGRLDRIMYV 194
Cdd:cd19511    81 KARQAAPCIIFFDEIDSLAPRRGQSDSSGVTdRVVSQLLTELDGIESLKGVVVIAATNRPDMIDPALLRPGRLDKLIYV 159
SpoVK COG0464
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ...
 18-279 1.09e-89

AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];


Pssm-ID: 440232 [Multi-domain]  Cd Length: 397  Bit Score: 272.55  E-value: 1.09e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  18 EGIVTVPDVTWDDVGSLNQVRKDLQLAVLAPVKYPEQLKKLGLSAPSGVLLCGPPGCGKTLLAKAVANEAGVNFISVKGP 97
Cdd:COG0464   146 EELLELREAILDDLGGLEEVKEELRELVALPLKRPELREEYGLPPPRGLLLYGPPGTGKTLLARALAGELGLPLIEVDLS 225

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  98 ELLNMYVGESERAVRTCFRRARNSAPCVIFFDEFDALCPRRSSHDSNGAARVVNQLLTEMDGIESRegVFVLAASNRPDI 177
Cdd:COG0464   226 DLVSKYVGETEKNLREVFDKARGLAPCVLFIDEADALAGKRGEVGDGVGRRVVNTLLTEMEELRSD--VVVIAATNRPDL 303

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 178 IDPAVLRpgRLDRIMYVGMPAREDRYDILQKLTKngtKPQLGPDVDLQVIAGLTEGYTGADLSGLVRAAATNALtqhisn 257
Cdd:COG0464   304 LDPALLR--RFDEIIFFPLPDAEERLEIFRIHLR---KRPLDEDVDLEELAEATEGLSGADIRNVVRRAALQAL------ 372

                         250       260
                  ....*....|....*....|..
gi 2569152555 258 gtLEGDIYVTFDDIRAALEKTK 279
Cdd:COG0464   373 --RLGREPVTTEDLLEALERED 392
PRK03992 PRK03992
proteasome-activating nucleotidase; Provisional
 20-277 1.07e-86

proteasome-activating nucleotidase; Provisional


Pssm-ID: 179699 [Multi-domain]  Cd Length: 389  Bit Score: 264.39  E-value: 1.07e-86
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  20 IVTVPDVTWDDVGSLNQVRKDLQLAVLAPVKYPEQLKKLGLSAPSGVLLCGPPGCGKTLLAKAVANEAGVNFISVKGPEL 99
Cdd:PRK03992  122 VIESPNVTYEDIGGLEEQIREVREAVELPLKKPELFEEVGIEPPKGVLLYGPPGTGKTLLAKAVAHETNATFIRVVGSEL 201

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 100 LNMYVGESERAVRTCFRRARNSAPCVIFFDEFDALCPRRsSHDSNGAARVVN----QLLTEMDGIESREGVFVLAASNRP 175
Cdd:PRK03992  202 VQKFIGEGARLVRELFELAREKAPSIIFIDEIDAIAAKR-TDSGTSGDREVQrtlmQLLAEMDGFDPRGNVKIIAATNRI 280

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 176 DIIDPAVLRPGRLDRIMYVGMPAREDRYDILQKLTKngtKPQLGPDVDLQVIAGLTEGYTGADLSGLVRAAATNALTqhi 255
Cdd:PRK03992  281 DILDPAILRPGRFDRIIEVPLPDEEGRLEILKIHTR---KMNLADDVDLEELAELTEGASGADLKAICTEAGMFAIR--- 354

                         250       260
                  ....*....|....*....|..
gi 2569152555 256 sngtlEGDIYVTFDDIRAALEK 277
Cdd:PRK03992  355 -----DDRTEVTMEDFLKAIEK 371
CDC48 TIGR01243
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two ...
 12-281 3.28e-79

AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus.


Pssm-ID: 273521 [Multi-domain]  Cd Length: 733  Bit Score: 254.45  E-value: 3.28e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  12 KPCAVREGIVT-VPDVTWDDVGSLNQVRKDLQLAVLAPVKYPEQLKKLGLSAPSGVLLCGPPGCGKTLLAKAVANEAGVN 90
Cdd:TIGR01243 160 REKPVREEIERkVPKVTYEDIGGLKEAKEKIREMVELPMKHPELFEHLGIEPPKGVLLYGPPGTGKTLLAKAVANEAGAY 239

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  91 FISVKGPELLNMYVGESERAVRTCFRRARNSAPCVIFFDEFDALCPRRSSHDSNGAARVVNQLLTEMDGIESREGVFVLA 170
Cdd:TIGR01243 240 FISINGPEIMSKYYGESEERLREIFKEAEENAPSIIFIDEIDAIAPKREEVTGEVEKRVVAQLLTLMDGLKGRGRVIVIG 319

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 171 ASNRPDIIDPAVLRPGRLDRIMYVGMPAREDRYDILQKLTKNgtKPqLGPDVDLQVIAGLTEGYTGADLSGLVRAAATNA 250
Cdd:TIGR01243 320 ATNRPDALDPALRRPGRFDREIVIRVPDKRARKEILKVHTRN--MP-LAEDVDLDKLAEVTHGFVGADLAALAKEAAMAA 396

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 2569152555 251 LTQHISNGTLE-----------GDIYVTFDDIRAALEKTKPS 281
Cdd:TIGR01243 397 LRRFIREGKINfeaeeipaevlKELKVTMKDFMEALKMVEPS 438
RecA-like_CDC48_r2-like cd19528
second of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or ...
 37-194 1.11e-78

second of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or VCP in metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the second of the two ATPase domains. CDC48's roles include in the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis, and in the formation of the nuclear envelope, and of the transitional endoplasmic reticulum (tER). This RecA-like_cdc48_r2-like subfamily belongs to the RecA-like family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410936 [Multi-domain]  Cd Length: 161  Bit Score: 235.87  E-value: 1.11e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  37 VRKDLQLAVLAPVKYPEQLKKLGLSAPSGVLLCGPPGCGKTLLAKAVANEAGVNFISVKGPELLNMYVGESERAVRTCFR 116
Cdd:cd19528     1 VKRELQELVQYPVEHPDKFLKFGMTPSKGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVRDIFD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 117 RARNSAPCVIFFDEFDALCPRR--SSHDSNGAA-RVVNQLLTEMDGIESREGVFVLAASNRPDIIDPAVLRPGRLDRIMY 193
Cdd:cd19528    81 KARAAAPCVLFFDELDSIAKARggNIGDAGGAAdRVINQILTEMDGMNTKKNVFIIGATNRPDIIDPAILRPGRLDQLIY 160


                  .
gi 2569152555 194 V 194
Cdd:cd19528   161 I 161
RecA-like_VCP_r2 cd19529
second of two ATPase domains of Valosin-containing protein-like ATPase (VAT) and similar ...
 37-194 1.25e-78

second of two ATPase domains of Valosin-containing protein-like ATPase (VAT) and similar ATPase domains; The Valosin-containing protein-like ATPase of Thermoplasma acidophilum (VAT), is an archaeal homolog of the ubiquitous Cdc48/p97. It is a protein unfoldase that functions in concert with the 20S proteasome by unfolding proteasome substrates and passing them on for degradation. VAT forms a homohexamer, each monomer contains two tandem ATPase domains, referred to as D1 and D2, and an N-terminal domain. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410937 [Multi-domain]  Cd Length: 159  Bit Score: 235.85  E-value: 1.25e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  37 VRKDLQLAVLAPVKYPEQLKKLGLSAPSGVLLCGPPGCGKTLLAKAVANEAGVNFISVKGPELLNMYVGESERAVRTCFR 116
Cdd:cd19529     1 VKQELKEAVEWPLLKPEVFKRLGIRPPKGILLYGPPGTGKTLLAKAVATESNANFISVKGPELLSKWVGESEKAIREIFR 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2569152555 117 RARNSAPCVIFFDEFDALCPRR-SSHDSNGAARVVNQLLTEMDGIESREGVFVLAASNRPDIIDPAVLRPGRLDRIMYV 194
Cdd:cd19529    81 KARQVAPCVIFFDEIDSIAPRRgTTGDSGVTERVVNQLLTELDGLEEMNGVVVIAATNRPDIIDPALLRAGRFDRLIYI 159
RecA-like_PEX1_r2 cd19526
second of two ATPase domains of Peroxisomal biogenesis factor 1 (PEX1); PEX1(also known as ...
 37-193 3.33e-73

second of two ATPase domains of Peroxisomal biogenesis factor 1 (PEX1); PEX1(also known as Peroxin-1)/PEX6 is a protein unfoldase; PEX1 and PEX6 form a heterohexameric Type-2 AAA-ATPase complex and are essential for peroxisome biogenesis as they are required for the import of folded proteins into the peroxisomal matrix. PEX-1 is required for stability of PEX5. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410934 [Multi-domain]  Cd Length: 158  Bit Score: 221.92  E-value: 3.33e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  37 VRKDLQLAVLAPVKYPEQLKKLGLSAPSGVLLCGPPGCGKTLLAKAVANEAGVNFISVKGPELLNMYVGESERAVRTCFR 116
Cdd:cd19526     1 VKKALEETIEWPSKYPKIFASSPLRLRSGILLYGPPGCGKTLLASAIASECGLNFISVKGPELLNKYIGASEQNVRDLFS 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2569152555 117 RARNSAPCVIFFDEFDALCPRRsSHDSNGAA-RVVNQLLTEMDGIESREGVFVLAASNRPDIIDPAVLRPGRLDRIMY 193
Cdd:cd19526    81 RAQSAKPCILFFDEFDSIAPKR-GHDSTGVTdRVVNQLLTQLDGVEGLDGVYVLAATSRPDLIDPALLRPGRLDKLVY 157
RecA-like_CDC48_NLV2_r1-like cd19503
first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and ...
 30-190 1.65e-72

first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and p97 or VCP metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the first of the two ATPase domains. This subfamily also includes the first of the two ATPase domains of NVL (nuclear VCP-like protein) 2, an isoform of NVL mainly present in the nucleolus, which is involved in ribosome biogenesis, in telomerase assembly and the regulation of telomerase activity, and in pre-rRNA processing. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410911 [Multi-domain]  Cd Length: 165  Bit Score: 220.24  E-value: 1.65e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  30 DVGSLNQVRKDLQLAVLAPVKYPEQLKKLGLSAPSGVLLCGPPGCGKTLLAKAVANEAGVNFISVKGPELLNMYVGESER 109
Cdd:cd19503     1 DIGGLDEQIASLKELIELPLKYPELFRALGLKPPRGVLLHGPPGTGKTLLARAVANEAGANFLSISGPSIVSKYLGESEK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 110 AVRTCFRRARNSAPCVIFFDEFDALCPRRSSHDSNGAARVVNQLLTEMDGIESREGVFVLAASNRPDIIDPAVLRPGRLD 189
Cdd:cd19503    81 NLREIFEEARSHAPSIIFIDEIDALAPKREEDQREVERRVVAQLLTLMDGMSSRGKVVVIAATNRPDAIDPALRRPGRFD 160


                  .
gi 2569152555 190 R 190
Cdd:cd19503   161 R 161
FtsH_fam TIGR01241
ATP-dependent metalloprotease FtsH; HflB(FtsH) is a pleiotropic protein required for correct ...
 24-286 1.43e-71

ATP-dependent metalloprotease FtsH; HflB(FtsH) is a pleiotropic protein required for correct cell division in bacteria. It has ATP-dependent zinc metalloprotease activity. It was formerly designated cell division protein FtsH. [Cellular processes, Cell division, Protein fate, Degradation of proteins, peptides, and glycopeptides]


Pssm-ID: 273520 [Multi-domain]  Cd Length: 495  Bit Score: 228.71  E-value: 1.43e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  24 PDVTWDDVGSLNQVRKDLQlAVLAPVKYPEQLKKLGLSAPSGVLLCGPPGCGKTLLAKAVANEAGVNFISVKGPELLNMY 103
Cdd:TIGR01241  50 PKVTFKDVAGIDEAKEELM-EIVDFLKNPSKFTKLGAKIPKGVLLVGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMF 128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 104 VGESERAVRTCFRRARNSAPCVIFFDEFDALCPRR-----SSHDSNgaARVVNQLLTEMDGIESREGVFVLAASNRPDII 178
Cdd:TIGR01241 129 VGVGASRVRDLFEQAKKNAPCIIFIDEIDAVGRQRgaglgGGNDER--EQTLNQLLVEMDGFGTNTGVIVIAATNRPDVL 206

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 179 DPAVLRPGRLDRIMYVGMPAREDRYDILQKLTKNgtKPqLGPDVDLQVIAGLTEGYTGADLSGLVRAAATNALTQHISNG 258
Cdd:TIGR01241 207 DPALLRPGRFDRQVVVDLPDIKGREEILKVHAKN--KK-LAPDVDLKAVARRTPGFSGADLANLLNEAALLAARKNKTEI 283

                         250       260
                  ....*....|....*....|....*...
gi 2569152555 259 TLEgDIYVTFDDIRAALEKTKPSVSPKE 286
Cdd:TIGR01241 284 TMN-DIEEAIDRVIAGPEKKSRVISEKE 310
HflB COG0465
ATP-dependent Zn proteases [Posttranslational modification, protein turnover, chaperones];
24-277 1.46e-68

ATP-dependent Zn proteases [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440233 [Multi-domain]  Cd Length: 583  Bit Score: 222.99  E-value: 1.46e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  24 PDVTWDDVGSLNQVRKDLQ-----LavlapvKYPEQLKKLGLSAPSGVLLCGPPGCGKTLLAKAVANEAGVNFISVKGPE 98
Cdd:COG0465   137 PKVTFDDVAGVDEAKEELQeivdfL------KDPEKFTRLGAKIPKGVLLVGPPGTGKTLLAKAVAGEAGVPFFSISGSD 210

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  99 LLNMYVG--ESeRaVRTCFRRARNSAPCVIFFDEFDALCPRR-----SSHDSngaaR--VVNQLLTEMDGIESREGVFVL 169
Cdd:COG0465   211 FVEMFVGvgAS-R-VRDLFEQAKKNAPCIIFIDEIDAVGRQRgaglgGGHDE----ReqTLNQLLVEMDGFEGNEGVIVI 284

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 170 AASNRPDIIDPAVLRPGRLDRIMYVGMPAREDRYDILQKLTKNgtKPqLGPDVDLQVIAGLTEGYTGADLSGLVRAAATN 249
Cdd:COG0465   285 AATNRPDVLDPALLRPGRFDRQVVVDLPDVKGREAILKVHARK--KP-LAPDVDLEVIARRTPGFSGADLANLVNEAALL 361

                         250       260
                  ....*....|....*....|....*...
gi 2569152555 250 AltqhisngTLEGDIYVTFDDIRAALEK 277
Cdd:COG0465   362 A--------ARRNKKAVTMEDFEEAIDR 381
RecA-like_protease cd19481
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ...
 37-194 1.67e-67

proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410889 [Multi-domain]  Cd Length: 158  Bit Score: 207.52  E-value: 1.67e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  37 VRKDLQLAVLAPVKYPEqLKKLGLSAPSGVLLCGPPGCGKTLLAKAVANEAGVNFISVKGPELLNMYVGESERAVRTCFR 116
Cdd:cd19481     1 LKASLREAVEAPRRGSR-LRRYGLGLPKGILLYGPPGTGKTLLAKALAGELGLPLIVVKLSSLLSKYVGESEKNLRKIFE 79

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2569152555 117 RARNSAPCVIFFDEFDALCPRRSSHDSNGAA-RVVNQLLTEMDGIESREGVFVLAASNRPDIIDPAVLRPGRLDRIMYV 194
Cdd:cd19481    80 RARRLAPCILFIDEIDAIGRKRDSSGESGELrRVLNQLLTELDGVNSRSKVLVIAATNRPDLLDPALLRPGRFDEVIEF 158
ftsH CHL00176
cell division protein; Validated
 25-278 1.24e-64

cell division protein; Validated


Pssm-ID: 214386 [Multi-domain]  Cd Length: 638  Bit Score: 214.14  E-value: 1.24e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  25 DVTWDDVGSLNQVRKDLQlAVLAPVKYPEQLKKLGLSAPSGVLLCGPPGCGKTLLAKAVANEAGVNFISVKGPELLNMYV 104
Cdd:CHL00176  179 GITFRDIAGIEEAKEEFE-EVVSFLKKPERFTAVGAKIPKGVLLVGPPGTGKTLLAKAIAGEAEVPFFSISGSEFVEMFV 257

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 105 GESERAVRTCFRRARNSAPCVIFFDEFDALCPRRSS-----HDSNgaARVVNQLLTEMDGIESREGVFVLAASNRPDIID 179
Cdd:CHL00176  258 GVGAARVRDLFKKAKENSPCIVFIDEIDAVGRQRGAgigggNDER--EQTLNQLLTEMDGFKGNKGVIVIAATNRVDILD 335

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 180 PAVLRPGRLDRIMYVGMPAREDRYDILQKLTKNgtKPqLGPDVDLQVIAGLTEGYTGADLSGLVRAAATNALTQHISNGT 259
Cdd:CHL00176  336 AALLRPGRFDRQITVSLPDREGRLDILKVHARN--KK-LSPDVSLELIARRTPGFSGADLANLLNEAAILTARRKKATIT 412

                         250
                  ....*....|....*....
gi 2569152555 260 lEGDIYVTFDDIRAALEKT 278
Cdd:CHL00176  413 -MKEIDTAIDRVIAGLEGT 430
COG1223 COG1223
Predicted ATPase, AAA+ superfamily [General function prediction only];
28-289 1.88e-64

Predicted ATPase, AAA+ superfamily [General function prediction only];


Pssm-ID: 440836 [Multi-domain]  Cd Length: 246  Bit Score: 202.81  E-value: 1.88e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  28 WDD-VGSlNQVRKDLQLaVLAPVKYPEQLKKLGLSAPSGVLLCGPPGCGKTLLAKAVANEAGVNFISVKGPELLNMYVGE 106
Cdd:COG1223     1 LDDvVGQ-EEAKKKLKL-IIKELRRRENLRKFGLWPPRKILFYGPPGTGKTMLAEALAGELKLPLLTVRLDSLIGSYLGE 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 107 SERAVRTCFRRARNsAPCVIFFDEFDALCPRRS-SHDSNGAARVVNQLLTEMDGIesREGVFVLAASNRPDIIDPAVLRp 185
Cdd:COG1223    79 TARNLRKLFDFARR-APCVIFFDEFDAIAKDRGdQNDVGEVKRVVNALLQELDGL--PSGSVVIAATNHPELLDSALWR- 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 186 gRLDRIMYVGMPAREDRYDILQKLTKnGTKPQLgpDVDLQVIAGLTEGYTGADLSGLVRAAATNALtqhisngtLEGDIY 265
Cdd:COG1223   155 -RFDEVIEFPLPDKEERKEILELNLK-KFPLPF--ELDLKKLAKKLEGLSGADIEKVLKTALKKAI--------LEDREK 222

                         250       260
                  ....*....|....*....|....
gi 2569152555 266 VTFDDIRAALEKTKPSVSPKEQLH 289
Cdd:COG1223   223 VTKEDLEEALKQRKERKKEPKKEG 246
RecA-like_FtsH cd19501
ATP-dependent zinc metalloprotease FtsH; FtsH ATPase is a processive, ATP-dependent zinc ...
 26-194 1.08e-63

ATP-dependent zinc metalloprotease FtsH; FtsH ATPase is a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. It is anchored to the cytoplasmic membrane such that the amino- and carboxy-termini are exposed to the cytoplasm. It presents a membrane-bound hexameric structure that is able to unfold and degrade protein substrates. It is comprised of an N-terminal transmembrane region and the larger C-terminal cytoplasmic region, which consists of an ATPase domain and a protease domain. This RecA-Like FTsH subfamily represents the ATPase domain, and belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410909 [Multi-domain]  Cd Length: 171  Bit Score: 198.23  E-value: 1.08e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  26 VTWDDVGSLNQVRKDLQlAVLAPVKYPEQLKKLGLSAPSGVLLCGPPGCGKTLLAKAVANEAGVNFISVKGPELLNMYVG 105
Cdd:cd19501     1 VTFKDVAGCEEAKEELK-EVVEFLKNPEKFTKLGAKIPKGVLLVGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 106 ESERAVRTCFRRARNSAPCVIFFDEFDALCPRRS-----SHDsnGAARVVNQLLTEMDGIESREGVFVLAASNRPDIIDP 180
Cdd:cd19501    80 VGASRVRDLFEQAKKNAPCIVFIDEIDAVGRKRGaglggGHD--EREQTLNQLLVEMDGFESNTGVIVIAATNRPDVLDP 157

                         170
                  ....*....|....
gi 2569152555 181 AVLRPGRLDRIMYV 194
Cdd:cd19501   158 ALLRPGRFDRQVYV 171
RecA-like_PAN_like cd19502
proteasome activating nucleotidase PAN and related proteasome subunits; This subfamily ...
 27-194 1.84e-63

proteasome activating nucleotidase PAN and related proteasome subunits; This subfamily contains ATPase subunits of the eukaryotic 26S proteasome, and of the archaeal proteasome which carry out ATP-dependent degradation of substrates of the ubiquitin-proteasome pathway. The eukaryotic 26S proteasome consists of a proteolytic 20S core particle (CP), and a 19S regulatory particle (RP) which provides the ATP-dependence and the specificity for ubiquitinated proteins. In the archaea the RP is a homohexameric complex of proteasome-activating nucleotidase (PAN). This subfamily also includes various eukaryotic 26S subunits including, proteasome 26S subunit, ATPase 2 (PSMC2, also known as S7 and MSS1) which is a member of the 19S RP and has a chaperone like activity; and proteasome 20S subunit alpha 6 (PSMA6, also known as IOTA, p27K, and PROS27) which is a member of the 20S CP. This RecA-like_PAN subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410910 [Multi-domain]  Cd Length: 171  Bit Score: 197.56  E-value: 1.84e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  27 TWDDVGSLNQVRKDLQLAVLAPVKYPEQLKKLGLSAPSGVLLCGPPGCGKTLLAKAVANEAGVNFISVKGPELLNMYVGE 106
Cdd:cd19502     1 TYEDIGGLDEQIREIREVVELPLKHPELFEELGIEPPKGVLLYGPPGTGKTLLAKAVANHTDATFIRVVGSELVQKYIGE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 107 SERAVRTCFRRARNSAPCVIFFDEFDALCPRRSSHDSNGAA---RVVNQLLTEMDGIESREGVFVLAASNRPDIIDPAVL 183
Cdd:cd19502    81 GARLVRELFEMAREKAPSIIFIDEIDAIGAKRFDSGTGGDRevqRTMLELLNQLDGFDPRGNIKVIMATNRPDILDPALL 160

                         170
                  ....*....|.
gi 2569152555 184 RPGRLDRIMYV 194
Cdd:cd19502   161 RPGRFDRKIEF 171
RecA-like_PEX6_r2 cd19527
second of two ATPase domains of Peroxisomal biogenesis factor 6 (PEX6); PEX6(also known as ...
 37-194 3.39e-63

second of two ATPase domains of Peroxisomal biogenesis factor 6 (PEX6); PEX6(also known as Peroxin61)/PEX1 is a protein unfoldase; PEX6 and PEX1 form a heterohexameric Type-2 AAA-ATPase complex and are essential for peroxisome biogenesis as they are required for the import of folded proteins into the peroxisomal matrix. This subfamily represents the second ATPase domain of PEX6. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410935 [Multi-domain]  Cd Length: 160  Bit Score: 196.58  E-value: 3.39e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  37 VRKDLQLAVLAPVKYPEqLKKLGLSAPSGVLLCGPPGCGKTLLAKAVANEAGVNFISVKGPELLNMYVGESERAVRTCFR 116
Cdd:cd19527     1 VKKEILDTIQLPLEHPE-LFSSGLRKRSGILLYGPPGTGKTLLAKAIATECSLNFLSVKGPELINMYIGESEANVREVFQ 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 117 RARNSAPCVIFFDEFDALCPRR-SSHDSNGAA-RVVNQLLTEMDGIE-SREGVFVLAASNRPDIIDPAVLRPGRLDRIMY 193
Cdd:cd19527    80 KARDAKPCVIFFDELDSLAPSRgNSGDSGGVMdRVVSQLLAELDGMSsSGQDVFVIGATNRPDLLDPALLRPGRFDKLLY 159


                  .
gi 2569152555 194 V 194
Cdd:cd19527   160 L 160
pup_AAA TIGR03689
proteasome ATPase; In the Actinobacteria, as shown for Mycobacterium tuberculosis, some ...
 23-208 4.18e-63

proteasome ATPase; In the Actinobacteria, as shown for Mycobacterium tuberculosis, some proteins are modified by ligation between an epsilon-amino group of a lysine side chain and the C-terminal carboxylate of the ubiquitin-like protein Pup. This modification leads to protein degradation by the archaeal-like proteasome found in the Actinobacteria. Members of this protein family belong to the AAA family of ATPases and tend to be clustered with the genes for Pup, the Pup ligase PafA, and structural components of the proteasome. This protein forms hexameric rings with ATPase activity. [Protein fate, Degradation of proteins, peptides, and glycopeptides]


Pssm-ID: 200312 [Multi-domain]  Cd Length: 512  Bit Score: 207.25  E-value: 4.18e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  23 VPDVTWDDVGSLNQVRKDLQLAVLAPVKYPEQLKKLGLSAPSGVLLCGPPGCGKTLLAKAVAN------EAGVN----FI 92
Cdd:TIGR03689 176 VPDVTYADIGGLGSQIEQIRDAVELPFLHPELYREYGLKPPKGVLLYGPPGCGKTLIAKAVANslaariGAEGGgksyFL 255

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  93 SVKGPELLNMYVGESERAVRTCFRRARNSA----PCVIFFDEFDALCPRRSSH-DSNGAARVVNQLLTEMDGIESREGVF 167
Cdd:TIGR03689 256 NIKGPELLNKYVGETERQIRLIFQRAREKAsegrPVIVFFDEMDSLFRTRGSGvSSDVETTVVPQLLAEIDGVESLDNVI 335

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 2569152555 168 VLAASNRPDIIDPAVLRPGRLDRIMYVGMPAREDRYDILQK 208
Cdd:TIGR03689 336 VIGASNREDMIDPAILRPGRLDVKIRIERPDAEAAADIFAK 376
RecA-like_CDC48_r1-like cd19519
first of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or VCP ...
 30-195 6.07e-60

first of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or VCP metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the first of the two ATPase domains. CDC48's roles include in the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis, and in the formation of the nuclear envelope, and of the transitional endoplasmic reticulum (tER). This RecA-like_cdc48_r1-like subfamily belongs to the RecA-like family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410927 [Multi-domain]  Cd Length: 166  Bit Score: 188.41  E-value: 6.07e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  30 DVG----SLNQVRKDLQLavlaPVKYPEQLKKLGLSAPSGVLLCGPPGCGKTLLAKAVANEAGVNFISVKGPELLNMYVG 105
Cdd:cd19519     1 DIGgcrkQLAQIREMVEL----PLRHPELFKAIGIKPPRGILLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSKLAG 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 106 ESERAVRTCFRRARNSAPCVIFFDEFDALCPRRSSHDSNGAARVVNQLLTEMDGIESREGVFVLAASNRPDIIDPAVLRP 185
Cdd:cd19519    77 ESESNLRKAFEEAEKNAPAIIFIDEIDAIAPKREKTHGEVERRIVSQLLTLMDGLKQRAHVIVMAATNRPNSIDPALRRF 156

                         170
                  ....*....|
gi 2569152555 186 GRLDRIMYVG 195
Cdd:cd19519   157 GRFDREIDIG 166
AAA pfam00004
ATPase family associated with various cellular activities (AAA); AAA family proteins often ...
 66-195 2.40e-59

ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.


Pssm-ID: 459627 [Multi-domain]  Cd Length: 130  Bit Score: 185.49  E-value: 2.40e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  66 VLLCGPPGCGKTLLAKAVANEAGVNFISVKGPELLNMYVGESERAVRTCFRRARNSAPCVIFFDEFDALCPRRSSHDSNG 145
Cdd:pfam00004   1 LLLYGPPGTGKTTLAKAVAKELGAPFIEISGSELVSKYVGESEKRLRELFEAAKKLAPCVIFIDEIDALAGSRGSGGDSE 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2569152555 146 AARVVNQLLTEMDGIESREG-VFVLAASNRPDIIDPAVLrpGRLDRIMYVG 195
Cdd:pfam00004  81 SRRVVNQLLTELDGFTSSNSkVIVIAATNRPDKLDPALL--GRFDRIIEFP 129
PTZ00454 PTZ00454
26S protease regulatory subunit 6B-like protein; Provisional
 24-251 4.79e-59

26S protease regulatory subunit 6B-like protein; Provisional


Pssm-ID: 240423 [Multi-domain]  Cd Length: 398  Bit Score: 193.44  E-value: 4.79e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  24 PDVTWDDVGSLNQVRKDLQLAVLAPVKYPEQLKKLGLSAPSGVLLCGPPGCGKTLLAKAVANEAGVNFISVKGPELLNMY 103
Cdd:PTZ00454  140 PDVTYSDIGGLDIQKQEIREAVELPLTCPELYEQIGIDPPRGVLLYGPPGTGKTMLAKAVAHHTTATFIRVVGSEFVQKY 219

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 104 VGESERAVRTCFRRARNSAPCVIFFDEFDALCPRRssHDSNGAA-----RVVNQLLTEMDGIESREGVFVLAASNRPDII 178
Cdd:PTZ00454  220 LGEGPRMVRDVFRLARENAPSIIFIDEVDSIATKR--FDAQTGAdrevqRILLELLNQMDGFDQTTNVKVIMATNRADTL 297

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2569152555 179 DPAVLRPGRLDRIMYVGMPAREDRYDILQKLTkngTKPQLGPDVDLQVIAGLTEGYTGADLSGLVRAAATNAL 251
Cdd:PTZ00454  298 DPALLRPGRLDRKIEFPLPDRRQKRLIFQTIT---SKMNLSEEVDLEDFVSRPEKISAADIAAICQEAGMQAV 367
hflB PRK10733
ATP-dependent zinc metalloprotease FtsH;
27-247 2.31e-58

ATP-dependent zinc metalloprotease FtsH;


Pssm-ID: 182683 [Multi-domain]  Cd Length: 644  Bit Score: 197.56  E-value: 2.31e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  27 TWDDVGSLNQVRKDLQlAVLAPVKYPEQLKKLGLSAPSGVLLCGPPGCGKTLLAKAVANEAGVNFISVKGPELLNMYVGE 106
Cdd:PRK10733  150 TFADVAGCDEAKEEVA-ELVEYLREPSRFQKLGGKIPKGVLMVGPPGTGKTLLAKAIAGEAKVPFFTISGSDFVEMFVGV 228

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 107 SERAVRTCFRRARNSAPCVIFFDEFDALCPRRSS-----HDSNgaARVVNQLLTEMDGIESREGVFVLAASNRPDIIDPA 181
Cdd:PRK10733  229 GASRVRDMFEQAKKAAPCIIFIDEIDAVGRQRGAglgggHDER--EQTLNQMLVEMDGFEGNEGIIVIAATNRPDVLDPA 306

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2569152555 182 VLRPGRLDRIMYVGMPAREDRYDILQKLTKngtKPQLGPDVDLQVIAGLTEGYTGADLSGLVRAAA 247
Cdd:PRK10733  307 LLRPGRFDRQVVVGLPDVRGREQILKVHMR---RVPLAPDIDAAIIARGTPGFSGADLANLVNEAA 369
cell_div_CdvC NF041006
cell division protein CdvC;
24-297 9.80e-57

cell division protein CdvC;


Pssm-ID: 468935 [Multi-domain]  Cd Length: 371  Bit Score: 186.86  E-value: 9.80e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  24 PDVTWDDVGSLNQVRKDLQLAVLAPVKYPEqLKKLGLsaPSGVLLCGPPGCGKTLLAKAVANEAGVNFISVKGPELLNMY 103
Cdd:NF041006   98 PKVTFSDIVGLEDVKEALKEAIVYPSKRPD-LFPLGW--PRGILLYGPPGCGKTMLAAAVANEIDSEFIHVDAASIMSKW 174

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 104 VGESERAVRTCFRRARNSA-----PCVIFFDEFDALCPRRSShDSNGAARVVNQLLTEMDGIE---SREGVFVLAASNRP 175
Cdd:NF041006  175 LGEAEKNVAKIFKKAREKSkeegkPAIIFIDEIDALLGVYSS-EVGGEVRVRNQFLKEMDGLQdksENYHVYVIGATNKP 253

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 176 DIIDPAVLRpgRLDRIMYVGMPAREDRYDILQKLTKngtKPQLGPDVDLQVIAGLTEGYTGADLSGLVRAAATNALTQHI 255
Cdd:NF041006  254 WRLDEPFLR--RFQKRIYIPLPDREQRLELLKYYTS---KIKLENDVDLDELAEMTEGYTASDIRDIVQAAHMRVVKEMF 328

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 2569152555 256 SNGtLEGDIYVTFDDIRAALEKTKPSVSPKEQLHYEKLRLKY 297
Cdd:NF041006  329 EKG-LGEPRPITMEDFKEVLKIRKPSVNQEMLKAYEAWHEKF 369
RecA-like_VPS4-like cd19509
ATPase domain of VPS4, ATAD1, K, KTNA1, Spastin, FIGL-1 and similar ATPase domains; This ...
 31-194 2.49e-52

ATPase domain of VPS4, ATAD1, K, KTNA1, Spastin, FIGL-1 and similar ATPase domains; This subfamily includes the ATPase domains of vacuolar protein sorting-associated protein 4 (VPS4), ATPase family AAA domain-containing protein 1 (ATAD1, also known as Thorase), Katanin p60 ATPase-containing subunit A1 (KTNA1), Spastin, and Fidgetin-Like 1 (FIGL-1). This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410917 [Multi-domain]  Cd Length: 163  Bit Score: 168.68  E-value: 2.49e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  31 VGSLNQVRKDLQLAVLAPVKYPEqLKKLGLSAPSGVLLCGPPGCGKTLLAKAVANEAGVNFISVKGPELLNMYVGESERA 110
Cdd:cd19509     1 IAGLDDAKEALKEAVILPSLRPD-LFPGLRGPPRGILLYGPPGTGKTLLARAVASESGSTFFSISASSLVSKWVGESEKI 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 111 VRTCFRRARNSAPCVIFFDEFDALCPRRSSHDSNGAARVVNQLLTEMDGIE--SREGVFVLAASNRPDIIDPAVLRpgRL 188
Cdd:cd19509    80 VRALFALARELQPSIIFIDEIDSLLSERGSGEHEASRRVKTEFLVQMDGVLnkPEDRVLVLGATNRPWELDEAFLR--RF 157


                  ....*.
gi 2569152555 189 DRIMYV 194
Cdd:cd19509   158 EKRIYI 163
RecA-like_NVL_r1-like cd19518
first of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL ...
 30-190 2.52e-52

first of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL exists in two forms with N-terminal extensions of different lengths in mammalian cells. NVL has two alternatively spliced isoforms, a short form, NVL1, and a long form, NVL2. NVL2, the major species, is mainly present in the nucleolus, whereas NVL1 is nucleoplasmic. Each has an N-terminal domain, followed by two tandem ATPase domains; this subfamily includes the first of the two ATPase domains. NVL2 is involved in the biogenesis of the 60S ribosome subunit by associating specifically with ribosome protein L5 and modulating the function of DOB1. NVL2 is also required for telomerase assembly and the regulation of telomerase activity, and is involved in pre-rRNA processing. The role of NVL1 is unclear. This RecA-like_NVL_r1-like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410926 [Multi-domain]  Cd Length: 169  Bit Score: 169.12  E-value: 2.52e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  30 DVGSLNQVRKDLQLAVLAPVKYPEQLKKLGLSAPSGVLLCGPPGCGKTLLAKAVANEAGVNFISVKGPELLNMYVGESER 109
Cdd:cd19518     1 DIGGMDSTLKELCELLIHPILPPEYFQHLGVEPPRGVLLHGPPGCGKTMLANAIAGELKVPFLKISATEIVSGVSGESEE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 110 AVRTCFRRARNSAPCVIFFDEFDALCPRRSSHDSNGAARVVNQLLTEMDGI----ESREGVFVLAASNRPDIIDPAVLRP 185
Cdd:cd19518    81 KIRELFDQAISNAPCIVFIDEIDAITPKRESAQREMERRIVSQLLTCMDELnnekTAGGPVLVIGATNRPDSLDPALRRA 160


                  ....*
gi 2569152555 186 GRLDR 190
Cdd:cd19518   161 GRFDR 165
PTZ00361 PTZ00361
26 proteosome regulatory subunit 4-like protein; Provisional
 24-277 3.82e-49

26 proteosome regulatory subunit 4-like protein; Provisional


Pssm-ID: 185575 [Multi-domain]  Cd Length: 438  Bit Score: 168.80  E-value: 3.82e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  24 PDVTWDDVGSLNQVRKDLQLAVLAPVKYPEQLKKLGLSAPSGVLLCGPPGCGKTLLAKAVANEAGVNFISVKGPELLNMY 103
Cdd:PTZ00361  178 PLESYADIGGLEQQIQEIKEAVELPLTHPELYDDIGIKPPKGVILYGPPGTGKTLLAKAVANETSATFLRVVGSELIQKY 257

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 104 VGESERAVRTCFRRARNSAPCVIFFDEFDALCPRRSSHDSNGA---ARVVNQLLTEMDGIESREGVFVLAASNRPDIIDP 180
Cdd:PTZ00361  258 LGDGPKLVRELFRVAEENAPSIVFIDEIDAIGTKRYDATSGGEkeiQRTMLELLNQLDGFDSRGDVKVIMATNRIESLDP 337

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 181 AVLRPGRLDRIMYVGMPAREDRYDILQKLTkngTKPQLGPDVDLQVIAGLTEGYTGADLSGLVRAAATNALTqhisngtl 260
Cdd:PTZ00361  338 ALIRPGRIDRKIEFPNPDEKTKRRIFEIHT---SKMTLAEDVDLEEFIMAKDELSGADIKAICTEAGLLALR-------- 406

                         250
                  ....*....|....*..
gi 2569152555 261 EGDIYVTFDDIRAALEK 277
Cdd:PTZ00361  407 ERRMKVTQADFRKAKEK 423
RecA-like_Yta7-like cd19517
ATPase domain of Saccharomyces cerevisiae Yta7 and similar ATPase domains; Saccharomyces ...
 30-193 1.43e-48

ATPase domain of Saccharomyces cerevisiae Yta7 and similar ATPase domains; Saccharomyces cerevisiae Yta7 is a chromatin-associated AAA-ATPase involved in regulation of chromatin dynamics. Its human ortholog ANCCA/ATAD2 transcriptionally activates pathways of malignancy in a broad range of cancers. The RecA-like_Yta7 subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410925 [Multi-domain]  Cd Length: 170  Bit Score: 159.60  E-value: 1.43e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  30 DVGSLNQVRKDLQLAVLAPVKYPEQLKKLGLSAPSGVLLCGPPGCGKTLLAKAVANEAG-----VNFISVKGPELLNMYV 104
Cdd:cd19517     1 DIGGLSHYINQLKEMVFFPLLYPEVFAKFKITPPRGVLFHGPPGTGKTLMARALAAECSkggqkVSFFMRKGADCLSKWV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 105 GESERAVRTCFRRARNSAPCVIFFDEFDALCPRRSSHDSNGAARVVNQLLTEMDGIESREGVFVLAASNRPDIIDPAVLR 184
Cdd:cd19517    81 GEAERQLRLLFEEAYRMQPSIIFFDEIDGLAPVRSSKQEQIHASIVSTLLALMDGLDNRGQVVVIGATNRPDALDPALRR 160


                  ....*....
gi 2569152555 185 PGRLDRIMY 193
Cdd:cd19517   161 PGRFDREFY 169
RecA-like_VPS4 cd19521
ATPase domain of vacuolar protein sorting-associated protein 4; Vacuolar protein ...
 24-194 1.92e-46

ATPase domain of vacuolar protein sorting-associated protein 4; Vacuolar protein sorting-associated protein 4 (Vps4) is believed to be involved in intracellular protein transport out of a prevacuolar endosomal compartment. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410929 [Multi-domain]  Cd Length: 170  Bit Score: 153.86  E-value: 1.92e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  24 PDVTWDDVGSLNQVRKDLQLAVLAPVKYPeQLKKLGLSAPSGVLLCGPPGCGKTLLAKAVANEAGVNFISVKGPELLNMY 103
Cdd:cd19521     2 PNVKWEDVAGLEGAKEALKEAVILPVKFP-HLFTGNRKPWSGILLYGPPGTGKSYLAKAVATEANSTFFSVSSSDLVSKW 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 104 VGESERAVRTCFRRARNSAPCVIFFDEFDALCPRRSSHDSNGAARVVNQLLTEMDGI-ESREGVFVLAASNRPDIIDPAV 182
Cdd:cd19521    81 MGESEKLVKQLFAMARENKPSIIFIDEVDSLCGTRGEGESEASRRIKTELLVQMNGVgNDSQGVLVLGATNIPWQLDSAI 160

                         170
                  ....*....|..
gi 2569152555 183 LRpgRLDRIMYV 194
Cdd:cd19521   161 RR--RFEKRIYI 170
RecA-like_ATAD1 cd19520
ATPase domain of ATPase family AAA domain-containing protein 1 and similar ATPase domains; ...
 30-188 1.08e-44

ATPase domain of ATPase family AAA domain-containing protein 1 and similar ATPase domains; ATPase family AAA domain-containing protein 1 (ATAD1, also known as Thorase) is an ATPase that plays a critical role in regulating the surface expression of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors, thereby regulating synaptic plasticity, learning and memory. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410928 [Multi-domain]  Cd Length: 166  Bit Score: 149.50  E-value: 1.08e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  30 DVGSLNQVRKDLQLAVLAPVKYPEQLKKLGL-SAPSGVLLCGPPGCGKTLLAKAVANEAGVNFISVKGPELLNMYVGESE 108
Cdd:cd19520     1 DIGGLDEVITELKELVILPLQRPELFDNSRLlQPPKGVLLYGPPGCGKTMLAKATAKEAGARFINLQVSSLTDKWYGESQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 109 RAVRTCFRRARNSAPCVIFFDEFDALCPRRSSHDSNGAARVVNQLLTEMDGIES--REGVFVLAASNRPDIIDPAVLR-- 184
Cdd:cd19520    81 KLVAAVFSLASKLQPSIIFIDEIDSFLRQRSSTDHEATAMMKAEFMSLWDGLSTdgNCRVIVMGATNRPQDLDEAILRrm 160


                  ....
gi 2569152555 185 PGRL 188
Cdd:cd19520   161 PKRF 164
RecA-like_KTNA1 cd19522
Katanin p60 ATPase-containing subunit A1; Katanin p60 ATPase-containing subunit A1 (KTNA1) is ...
 30-194 7.95e-42

Katanin p60 ATPase-containing subunit A1; Katanin p60 ATPase-containing subunit A1 (KTNA1) is the catalytic subunit of the Katanin complex which is severs microtubules in an ATP-dependent manner, and is implicated in multiple aspects of microtubule dynamics. In addition to the p60 catalytic ATPase subunit, Katanin contains an accessory subunit (p80 or p80-like). The microtubule-severing activity of the ATPase is essential for female meiotic spindle assembly, and male gamete production; and the katanin complex severing microtubules is under tight regulation during the transition from the meiotic to mitotic stage to allow proper embryogenesis. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410930 [Multi-domain]  Cd Length: 170  Bit Score: 142.05  E-value: 7.95e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  30 DVGSLNQVRKDLQLAVLAPVKYPEQLKklGLSAP-SGVLLCGPPGCGKTLLAKAVANEAGVNFISVKGPELLNMYVGESE 108
Cdd:cd19522     1 DIADLEEAKKLLEEAVVLPMWMPEFFK--GIRRPwKGVLMVGPPGTGKTLLAKAVATECGTTFFNVSSSTLTSKYRGESE 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 109 RAVRTCFRRARNSAPCVIFFDEFDALCPRRSSHDSNGAA-RVVNQLLTEMDGI-------ESREGVFVLAASNRPDIIDP 180
Cdd:cd19522    79 KLVRLLFEMARFYAPTTIFIDEIDSICSRRGTSEEHEASrRVKSELLVQMDGVggasendDPSKMVMVLAATNFPWDIDE 158

                         170
                  ....*....|....
gi 2569152555 181 AVLRpgRLDRIMYV 194
Cdd:cd19522   159 ALRR--RLEKRIYI 170
RecA-like_NSF-SEC18_r1-like cd19504
first of two ATPase domains of NSF and SEC18, and similar ATPase domains; ...
 52-189 2.02e-39

first of two ATPase domains of NSF and SEC18, and similar ATPase domains; N-ethylmaleimide-sensitive factor (NSF) and Saccharomyces cerevisiae Vesicular-fusion protein Sec18, key factors for eukaryotic trafficking, are ATPases and SNARE disassembly chaperones. NSF/Sec18 activate or prime SNAREs, the terminal catalysts of membrane fusion. Sec18/NSF associates with SNARE complexes through binding Sec17/alpha-SNAP. Sec18 has an N-terminal cap domain and two nucleotide-binding domains (D1 and D2) which form the two rings of the hexameric complex. The hydrolysis of ATP by D1 generates most of the energy necessary to disassemble inactive SNARE bundles, while the D2 ring binds ATP to stabilize the homohexamer. This subfamily includes the first (D1) ATPase domain of NSF/Sec18, and belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410912 [Multi-domain]  Cd Length: 177  Bit Score: 136.08  E-value: 2.02e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  52 PEQLKKLGLSAPSGVLLCGPPGCGKTLLAKAV-----ANEAGVnfisVKGPELLNMYVGESERAVRTCFRRAR------- 119
Cdd:cd19504    24 PEIVEQLGCKHVKGILLYGPPGTGKTLMARQIgkmlnAREPKI----VNGPEILNKYVGESEANIRKLFADAEeeqrrlg 99

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2569152555 120 -NSAPCVIFFDEFDALCPRR-SSHDSNGAA-RVVNQLLTEMDGIESREGVFVLAASNRPDIIDPAVLRPGRLD 189
Cdd:cd19504   100 aNSGLHIIIFDEIDAICKQRgSMAGSTGVHdTVVNQLLSKIDGVEQLNNILVIGMTNRKDLIDEALLRPGRLE 172
RecA-like_spastin cd19524
ATPase domain of spastin; Spastin is an ATP-dependent microtubule-severing protein involved in ...
 30-194 2.78e-36

ATPase domain of spastin; Spastin is an ATP-dependent microtubule-severing protein involved in microtubule dynamics; it specifically recognizes and cuts microtubules that are polyglutamylated. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410932 [Multi-domain]  Cd Length: 164  Bit Score: 127.66  E-value: 2.78e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  30 DVGSLNQVRKDLQLAVLAPVKYPEQLKklGLSAPS-GVLLCGPPGCGKTLLAKAVANEAGVNFISVKGPELLNMYVGESE 108
Cdd:cd19524     1 DIAGQDLAKQALQEMVILPSLRPELFT--GLRAPArGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGE 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 109 RAVRTCFRRARNSAPCVIFFDEFDALCPRRSSHDSNGAARVVNQLLTEMDGIESR--EGVFVLAASNRPDIIDPAVLRpg 186
Cdd:cd19524    79 KLVRALFAVARELQPSIIFIDEVDSLLSERSEGEHEASRRLKTEFLIEFDGVQSNgdDRVLVMGATNRPQELDDAVLR-- 156


                  ....*...
gi 2569152555 187 RLDRIMYV 194
Cdd:cd19524   157 RFTKRVYV 164
RecA-like_Figl-1 cd19525
ATPase domain of Fidgetin-Like 1 (FIGL-1); FIGL-1 may participate in DNA repair in the nucleus; ...
 24-194 4.30e-36

ATPase domain of Fidgetin-Like 1 (FIGL-1); FIGL-1 may participate in DNA repair in the nucleus; it may be involved in DNA double-strand break repair via homologous recombination. Caenorhabditis elegans FIGL-1 is a nuclear protein and controls the mitotic progression in the germ line and mouse FIGL-1 may be involved in the control of male meiosis. human FIGL-1 has been shown to be a centrosome protein involved in ciliogenesis perhaps as a microtubule-severing protein. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410933 [Multi-domain]  Cd Length: 186  Bit Score: 127.80  E-value: 4.30e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  24 PDVTWDDVGSLNQVRKDLQLAVLAPVKYPEQLKklGLSAP-SGVLLCGPPGCGKTLLAKAVANEAGVNFISVKGPELLNM 102
Cdd:cd19525    17 PPINWADIAGLEFAKKTIKEIVVWPMLRPDIFT--GLRGPpKGILLFGPPGTGKTLIGKCIASQSGATFFSISASSLTSK 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 103 YVGESERAVRTCFRRARNSAPCVIFFDEFDALCPRRSSHDSNGAARVVNQLLTEMDGI--ESREGVFVLAASNRPDIIDP 180
Cdd:cd19525    95 WVGEGEKMVRALFSVARCKQPAVIFIDEIDSLLSQRGEGEHESSRRIKTEFLVQLDGAttSSEDRILVVGATNRPQEIDE 174

                         170
                  ....*....|....
gi 2569152555 181 AVLRpgRLDRIMYV 194
Cdd:cd19525   175 AARR--RLVKRLYI 186
RecA-like_Ycf46-like cd19507
ATPase domain of Ycf46 and similar ATPase domains; Ycf46 may play a role in the regulation of ...
 30-194 9.14e-30

ATPase domain of Ycf46 and similar ATPase domains; Ycf46 may play a role in the regulation of photosynthesis in cyanobacteria, especially in CO2 uptake and utilization. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410915 [Multi-domain]  Cd Length: 161  Bit Score: 110.54  E-value: 9.14e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  30 DVGSLNQVRKDLQLAVLApvkYPEQLKKLGLSAPSGVLLCGPPGCGKTLLAKAVANEAGVNFISVKGPELLNMYVGESER 109
Cdd:cd19507     1 DVGGLDNLKDWLKKRKAA---FSKQASAYGLPTPKGLLLVGIQGTGKSLTAKAIAGVWQLPLLRLDMGRLFGGLVGESES 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 110 AVRTCFRRARNSAPCVIFFDEFD-ALCPRRSSHDSNGAARVVNQLLTEMDgiESREGVFVLAASNRPDIIDPAVLRPGRL 188
Cdd:cd19507    78 RLRQMIQTAEAIAPCVLWIDEIEkGFSNADSKGDSGTSSRVLGTFLTWLQ--EKKKPVFVVATANNVQSLPPELLRKGRF 155


                  ....*.
gi 2569152555 189 DRIMYV 194
Cdd:cd19507   156 DEIFFV 161
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
 60-195 1.17e-29

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 109.93  E-value: 1.17e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  60 LSAPSGVLLCGPPGCGKTLLAKAVANEA---GVNFISVKGPELLNMYVGESER---AVRTCFRRARNSAPCVIFFDEFDA 133
Cdd:cd00009    16 LPPPKNLLLYGPPGTGKTTLARAIANELfrpGAPFLYLNASDLLEGLVVAELFghfLVRLLFELAEKAKPGVLFIDEIDS 95

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2569152555 134 LCPRRSshdsngaARVVNQLLTEMDGIESREGVFVLAASNRPDIIDPAVLRPGRLDRIMYVG 195
Cdd:cd00009    96 LSRGAQ-------NALLRVLETLNDLRIDRENVRVIGATNRPLLGDLDRALYDRLDIRIVIP 150
ycf46 CHL00195
Ycf46; Provisional
 24-280 8.21e-29

Ycf46; Provisional


Pssm-ID: 177094 [Multi-domain]  Cd Length: 489  Bit Score: 114.73  E-value: 8.21e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  24 PDVTWDDVGSLNQVRKDLQLAVLApvkYPEQLKKLGLSAPSGVLLCGPPGCGKTLLAKAVANEAGVNFISVKGPELLNMY 103
Cdd:CHL00195  223 VNEKISDIGGLDNLKDWLKKRSTS---FSKQASNYGLPTPRGLLLVGIQGTGKSLTAKAIANDWQLPLLRLDVGKLFGGI 299

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 104 VGESERAVRTCFRRARNSAPCVIFFDEFD-ALCPRRSSHDSNGAARVVNQLLTEMDgiESREGVFVLAASNRPDIIDPAV 182
Cdd:CHL00195  300 VGESESRMRQMIRIAEALSPCILWIDEIDkAFSNSESKGDSGTTNRVLATFITWLS--EKKSPVFVVATANNIDLLPLEI 377

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 183 LRPGRLDRIMYVGMPAREDRYDILQKLTKNgTKPQLGPDVDLQVIAGLTEGYTGADLSGLVRAAATNALTQHISngtleg 262
Cdd:CHL00195  378 LRKGRFDEIFFLDLPSLEEREKIFKIHLQK-FRPKSWKKYDIKKLSKLSNKFSGAEIEQSIIEAMYIAFYEKRE------ 450

                         250
                  ....*....|....*...
gi 2569152555 263 diyVTFDDIRAALEKTKP 280
Cdd:CHL00195  451 ---FTTDDILLALKQFIP 465
RecA-like_fidgetin cd19523
ATPase domain of fidgetin; Fidgetin (FIGN) is a ATP-dependent microtubule severing protein. ...
 30-184 2.74e-21

ATPase domain of fidgetin; Fidgetin (FIGN) is a ATP-dependent microtubule severing protein. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410931 [Multi-domain]  Cd Length: 163  Bit Score: 88.02  E-value: 2.74e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  30 DVGSLNQVRKDLQLAVLAPVKYPEQLKKLgLSAPSGVLLCGPPGCGKTLLAKAVANEAGVNFISVKGPELLNMYVGESER 109
Cdd:cd19523     1 DIAGLGALKAAIKEEVLWPLLRPDAFSGL-LRLPRSILLFGPRGTGKTLLGRCLASQLGATFLRLRGSTLVAKWAGEGEK 79

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2569152555 110 AVRTCFRRARNSAPCVIFFDEFDALCPRRSSHDSNGaARVVNQLLTEMDGI--ESREGVFVLAASNRPDIIDPAVLR 184
Cdd:cd19523    80 ILQASFLAARCRQPSVLFISDLDALLSSQDDEASPV-GRLQVELLAQLDGVlgSGEDGVLVVCTTSKPEEIDESLRR 155
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 63-195 4.89e-19

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 81.65  E-value: 4.89e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555   63 PSGVLLCGPPGCGKTLLAKAVANEAGVNFISVK-----------------GPELLNMYVGESERAVRTCFRRARNSAPCV 125
Cdd:smart00382   2 GEVILIVGPPGSGKTTLARALARELGPPGGGVIyidgedileevldqlllIIVGGKKASGSGELRLRLALALARKLKPDV 81

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  126 IFFDEFDALCPRRSSHDsngaaRVVNQLLTEMDGIESREGVFVLAASNRPDIIDPAVLRPgRLDRIMYVG 195
Cdd:smart00382  82 LILDEITSLLDAEQEAL-----LLLLEELRLLLLLKSEKNLTVILTTNDEKDLGPALLRR-RFDRRIVLL 145
RecA-like_BCS1 cd19510
Mitochondrial chaperone BCS1; Mitochondrial chaperone BCS1 is necessary for the assembly of ...
 65-194 8.67e-13

Mitochondrial chaperone BCS1; Mitochondrial chaperone BCS1 is necessary for the assembly of mitochondrial respiratory chain complex III and plays an important role in the maintenance of mitochondrial tubular networks, respiratory chain assembly and formation of the LETM1 complex. RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410918 [Multi-domain]  Cd Length: 153  Bit Score: 64.68  E-value: 8.67e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  65 GVLLCGPPGCGKTLLAKAVANEAGVNFIsvkgpeLLNMyvgeSERaVRTCFRRAR--NSAP--CVIFFDEFDA-----LC 135
Cdd:cd19510    25 GYLLYGPPGTGKSSFIAALAGELDYDIC------DLNL----SEV-VLTDDRLNHllNTAPkqSIILLEDIDAafesrEH 93

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 136 PRRSSHDSNGAARV-VNQLLTEMDGIESREGVFVLAASNRPDIIDPAVLRPGRLDRIMYV 194
Cdd:cd19510    94 NKKNPSAYGGLSRVtFSGLLNALDGVASSEERIVFMTTNHIERLDPALIRPGRVDMKIYM 153
RecA-like_Pch2-like cd19508
ATPase domain of Pachytene checkpoint 2 (Pch2) and similar ATPase domains; Pch2 (known as ...
 66-194 6.86e-12

ATPase domain of Pachytene checkpoint 2 (Pch2) and similar ATPase domains; Pch2 (known as Thyroid hormone receptor interactor 13 (TRIP13) and 16E1BP) is a key regulator of specific chromosomal events, like the control of G2/prophase processes such as DNA break formation and recombination, checkpoint signaling, and chromosome synapsis. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion


Pssm-ID: 410916 [Multi-domain]  Cd Length: 199  Bit Score: 63.23  E-value: 6.86e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  66 VLLCGPPGCGKTLLAKAVANEAGVN---------FISVKGPELLNMYVGESERAVRTCFRR------ARNSAPCVIFfDE 130
Cdd:cd19508    55 VLLHGPPGTGKTSLCKALAQKLSIRlssryrygqLIEINSHSLFSKWFSESGKLVTKMFQKiqelidDKDALVFVLI-DE 133

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2569152555 131 FDALCPRR----SSHDSNGAARVVNQLLTEMDGIESREGVFVLAASNRPDIIDPAVLrpGRLDRIMYV 194
Cdd:cd19508   134 VESLAAARsassSGTEPSDAIRVVNAVLTQIDRIKRYHNNVILLTSNLLEKIDVAFV--DRADIKQYI 199
RecA-like_ATAD3-like cd19512
ATPase domains of ATPase AAA-domain protein 3A (ATAD3A), -3B, and -3C, and similar ATPase ...
 66-182 3.00e-10

ATPase domains of ATPase AAA-domain protein 3A (ATAD3A), -3B, and -3C, and similar ATPase domains; ATPase AAA-domain protein 3 (ATAD3) is a ubiquitously expressed mitochondrial protein involved in mitochondrial dynamics, DNA-nucleoid structural organization, cholesterol transport and steroidogenesis. The ATAD3 gene family in human comprises three paralog genes: ATAD3A, ATAD3B and ATAD3C. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410920 [Multi-domain]  Cd Length: 150  Bit Score: 57.54  E-value: 3.00e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  66 VLLCGPPGCGKTLLAKAVANEAGVNFISVKGPELLNMYvGESERAVRTCFRRARNSAPCVIFF-DEFDA-LCPRRSSHDS 143
Cdd:cd19512    25 ILFYGPPGTGKTLFAKKLALHSGMDYAIMTGGDVAPMG-REGVTAIHKVFDWANTSRRGLLLFvDEADAfLRKRSTEKIS 103

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 2569152555 144 NGAARVVNQLLTEMdGIESREGVFVLaASNRPDIIDPAV 182
Cdd:cd19512   104 EDLRAALNAFLYRT-GEQSNKFMLVL-ASNQPEQFDWAI 140
AAA_lid_3 pfam17862
AAA+ lid domain; This entry represents the alpha helical AAA+ lid domain that is found to the ...
 221-261 2.66e-09

AAA+ lid domain; This entry represents the alpha helical AAA+ lid domain that is found to the C-terminus of AAA domains.


Pssm-ID: 465537 [Multi-domain]  Cd Length: 45  Bit Score: 51.77  E-value: 2.66e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 2569152555 221 DVDLQVIAGLTEGYTGADLSGLVRAAATNALTQHISNGTLE 261
Cdd:pfam17862   1 DVDLEELAERTEGFSGADLEALCREAALAALRRGLEAVTQE 41
RecA-like_Ycf2 cd19505
ATPase domain of plant YCF2; Ycf2 is a chloroplast ATPase which has an essential function; ...
 57-194 8.41e-09

ATPase domain of plant YCF2; Ycf2 is a chloroplast ATPase which has an essential function; however, its function remains unclear. The gene encoding YCF2 is the largest known plastid gene in angiosperms and has been used to predict phylogenetic relationships. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410913 [Multi-domain]  Cd Length: 161  Bit Score: 53.53  E-value: 8.41e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  57 KLGLSAPSGVLLCGPPGCGKTLLAKAVANEAGVNFISVKGPELLN--------------MYVGESERAVRTCFRRARNSA 122
Cdd:cd19505     6 RLGLSPSKGILLIGSIETGRSYLIKSLAANSYVPLIRISLNKLLYnkpdfgnddwidgmLILKESLHRLNLQFELAKAMS 85

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2569152555 123 PCVIFFDEFDALCPRRSSHDSNG-----AARVVNQLLTEMDGIESREgVFVLAASNRPDIIDPAVLRPGRLDRIMYV 194
Cdd:cd19505    86 PCIIWIPNIHELNVNRSTQNLEEdpkllLGLLLNYLSRDFEKSSTRN-ILVIASTHIPQKVDPALIAPNRLDTCINI 161
MoxR COG0714
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway ...
 66-275 1.94e-08

MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 440478 [Multi-domain]  Cd Length: 292  Bit Score: 54.40  E-value: 1.94e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  66 VLLCGPPGCGKTLLAKAVANEAGVNFISVKG-PELL-------NMYVGESERavrtcFR-RARnsaP---CVIFFDEFDa 133
Cdd:COG0714    34 LLLEGVPGVGKTTLAKALARALGLPFIRIQFtPDLLpsdilgtYIYDQQTGE-----FEfRPG---PlfaNVLLADEIN- 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 134 lcprRSShdsngaARVVNQLLTEMD----GIESR-----EGVFVLAASNRPDIIDPAVLRPGRLDRIM---YVGMPARED 201
Cdd:COG0714   105 ----RAP------PKTQSALLEAMEerqvTIPGGtyklpEPFLVIATQNPIEQEGTYPLPEAQLDRFLlklYIGYPDAEE 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 202 RYDILqKLTKNGTKPQLGPDVDLQVIAGL------------TEGY---------TGADLS---------GLVRAAATNAL 251
Cdd:COG0714   175 EREIL-RRHTGRHLAEVEPVLSPEELLALqelvrqvhvseaVLDYivdlvratrEHPDLRkgpsprasiALLRAARALAL 253

                         250       260
                  ....*....|....*....|....
gi 2569152555 252 tqhisngtLEGDIYVTFDDIRAAL 275
Cdd:COG0714   254 --------LDGRDYVTPDDVKAVA 269
RuvB_N pfam05496
Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the ...
 27-99 2.07e-07

Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the RuvABC revolvasome which catalyzes the resolution of Holliday junctions that arise during genetic recombination and DNA repair. Branch migration is catalyzed by the RuvB protein that is targeted to the Holliday junction by the structure specific RuvA protein. This family contains the N-terminal region of the protein.


Pssm-ID: 398900 [Multi-domain]  Cd Length: 159  Bit Score: 49.81  E-value: 2.07e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2569152555  27 TWDDVGSLNQVRKDLQLAVLAPVKYPEqlkklglsAPSGVLLCGPPGCGKTLLAKAVANEAGVNFISVKGPEL 99
Cdd:pfam05496   5 TLDEYIGQEKVKENLKIFIEAAKQRGE--------ALDHVLLYGPPGLGKTTLANIIANEMGVNIRITSGPAI 69
T7SS_EccA TIGR03922
type VII secretion AAA-ATPase EccA; This model represents the AAA family ATPase, EccA, of the ...
 67-177 3.25e-07

type VII secretion AAA-ATPase EccA; This model represents the AAA family ATPase, EccA, of the actinobacterial flavor of type VII secretion systems. Species such as Mycobacterium tuberculosis have several instances of this system per genome, designated EccA1, EccA2, etc. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 188437 [Multi-domain]  Cd Length: 557  Bit Score: 51.38  E-value: 3.25e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  67 LLCGPPGCGKTLLAKAVANE-AGV------NFISVKGPELLNMYVGESERAVRTCFRRARNSapcVIFFDEFDALCPRRS 139
Cdd:TIGR03922 316 LFAGPPGTGKTTIARVVAKIyCGLgvlrkpLVREVSRADLIGQYIGESEAKTNEIIDSALGG---VLFLDEAYTLVETGY 392

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 2569152555 140 SHDSNGAARVVNQLLTEMDGieSREGVFVLAASNRPDI 177
Cdd:TIGR03922 393 GQKDPFGLEAIDTLLARMEN--DRDRLVVIGAGYRKDL 428
ruvB PRK00080
Holliday junction branch migration DNA helicase RuvB;
66-99 4.81e-07

Holliday junction branch migration DNA helicase RuvB;


Pssm-ID: 234619 [Multi-domain]  Cd Length: 328  Bit Score: 50.51  E-value: 4.81e-07
                          10        20        30
                  ....*....|....*....|....*....|....
gi 2569152555  66 VLLCGPPGCGKTLLAKAVANEAGVNFISVKGPEL 99
Cdd:PRK00080   54 VLLYGPPGLGKTTLANIIANEMGVNIRITSGPAL 87
ruvB TIGR00635
Holliday junction DNA helicase, RuvB subunit; All proteins in this family for which functions ...
 27-99 2.18e-06

Holliday junction DNA helicase, RuvB subunit; All proteins in this family for which functions are known are 5'-3' DNA helicases that, as part of a complex with RuvA homologs serve as a 5'-3' Holliday junction helicase. RuvA specifically binds Holliday junctions as a sandwich of two tetramers and maintains the configuration of the junction. It forms a complex with two hexameric rings of RuvB, the subunit that contains helicase activity. The complex drives ATP-dependent branch migration of the Holliday junction recombination intermediate. The endonuclease RuvC resolves junctions. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129721 [Multi-domain]  Cd Length: 305  Bit Score: 48.07  E-value: 2.18e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2569152555  27 TWDDVGSLNQVRKDLQLAVLAPVKYPEQLKKlglsapsgVLLCGPPGCGKTLLAKAVANEAGVNFISVKGPEL 99
Cdd:TIGR00635   2 LLAEFIGQEKVKEQLQLFIEAAKMRQEALDH--------LLLYGPPGLGKTTLAHIIANEMGVNLKITSGPAL 66
RuvB COG2255
Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, ...
 66-97 3.93e-06

Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, recombination and repair];


Pssm-ID: 441856 [Multi-domain]  Cd Length: 337  Bit Score: 47.38  E-value: 3.93e-06
                          10        20        30
                  ....*....|....*....|....*....|..
gi 2569152555  66 VLLCGPPGCGKTLLAKAVANEAGVNFISVKGP 97
Cdd:COG2255    57 VLLYGPPGLGKTTLAHIIANEMGVNIRITSGP 88
AAA_2 pfam07724
AAA domain (Cdc48 subfamily); This Pfam entry includes some of the AAA proteins not detected ...
 66-136 1.61e-05

AAA domain (Cdc48 subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.


Pssm-ID: 400187 [Multi-domain]  Cd Length: 168  Bit Score: 44.49  E-value: 1.61e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  66 VLLCGPPGCGKTLLAKAVANEAGV---NFISVKGPELL-----NM-------YVGESERAVRTCFRRARnsAPCVIFFDE 130
Cdd:pfam07724   6 FLFLGPTGVGKTELAKALAELLFGderALIRIDMSEYMeehsvSRligappgYVGYEEGGQLTEAVRRK--PYSIVLIDE 83


                  ....*.
gi 2569152555 131 FDALCP 136
Cdd:pfam07724  84 IEKAHP 89
TIP49 COG1224
DNA helicase TIP49, TBP-interacting protein [Transcription];
54-112 2.31e-05

DNA helicase TIP49, TBP-interacting protein [Transcription];


Pssm-ID: 440837 [Multi-domain]  Cd Length: 452  Bit Score: 45.35  E-value: 2.31e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2569152555  54 QLKKLGLSAPSGVLLCGPPGCGKTLLAKAVANEAG--VNFISVKGPELLNMYVGESE---RAVR 112
Cdd:COG1224    55 KMIKEGKMAGKGILIVGPPGTGKTALAVAIARELGedTPFVAISGSEIYSAELKKTEflmQALR 118
TIP49 pfam06068
TIP49 P-loop domain; This family consists of the C-terminal region of several eukaryotic and ...
 65-118 3.49e-05

TIP49 P-loop domain; This family consists of the C-terminal region of several eukaryotic and archaeal RuvB-like 1 (Pontin or TIP49a) and RuvB-like 2 (Reptin or TIP49b) proteins. The N-terminal domain contains the pfam00004 domain. In zebrafish, the liebeskummer (lik) mutation, causes development of hyperplastic embryonic hearts. lik encodes Reptin, a component of a DNA-stimulated ATPase complex. Beta-catenin and Pontin, a DNA-stimulated ATPase that is often part of complexes with Reptin, are in the same genetic pathways. The Reptin/Pontin ratio serves to regulate heart growth during development, at least in part via the beta-catenin pathway. TBP-interacting protein 49 (TIP49) was originally identified as a TBP-binding protein, and two related proteins are encoded by individual genes, tip49a and b. Although the function of this gene family has not been elucidated, they are supposed to play a critical role in nuclear events because they interact with various kinds of nuclear factors and have DNA helicase activities.TIP49a has been suggested to act as an autoantigen in some patients with autoimmune diseases.


Pssm-ID: 399217 [Multi-domain]  Cd Length: 347  Bit Score: 44.61  E-value: 3.49e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2569152555  65 GVLLCGPPGCGKTLLAKAVANEAG--VNFISVKGPELLNMYVGESErAVRTCFRRA 118
Cdd:pfam06068  52 AVLIAGPPGTGKTALAIAISKELGedTPFTSISGSEVYSLEMKKTE-ALTQAFRKA 106
ABC_ATPase cd00267
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...
 49-184 7.36e-05

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213179 [Multi-domain]  Cd Length: 157  Bit Score: 42.23  E-value: 7.36e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  49 VKYPEQ--LKKLGLSAPSG--VLLCGPPGCGKTLLAKAVANEAGVN--FISVKGPELLNMYVGESERAVRTCF------- 115
Cdd:cd00267     7 FRYGGRtaLDNVSLTLKAGeiVALVGPNGSGKSTLLRAIAGLLKPTsgEILIDGKDIAKLPLEELRRRIGYVPqlsggqr 86

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2569152555 116 RR---ARN--SAPCVIFFDE-FDALcprrsshDSNGAARVVNqLLTEMdgieSREGVFVLAASNRPDIIDPAVLR 184
Cdd:cd00267    87 QRvalARAllLNPDLLLLDEpTSGL-------DPASRERLLE-LLREL----AEEGRTVIIVTHDPELAELAADR 149
PRK08116 PRK08116
hypothetical protein; Validated
 53-101 7.58e-05

hypothetical protein; Validated


Pssm-ID: 236153 [Multi-domain]  Cd Length: 268  Bit Score: 43.47  E-value: 7.58e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2569152555  53 EQLKKLGLsapsGVLLCGPPGCGKTLLAKAVAN---EAGVNFISVKGPELLN 101
Cdd:PRK08116  108 EEMKKENV----GLLLWGSVGTGKTYLAACIANeliEKGVPVIFVNFPQLLN 155
DnaC COG1484
DNA replication protein DnaC [Replication, recombination and repair];
65-131 8.98e-05

DNA replication protein DnaC [Replication, recombination and repair];


Pssm-ID: 441093 [Multi-domain]  Cd Length: 242  Bit Score: 42.85  E-value: 8.98e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2569152555  65 GVLLCGPPGCGKTLLAKAVANEA---G--VNFISVkgPELLN-MYVGESERAVRTCFRRARnSAPCVIfFDEF 131
Cdd:COG1484   101 NLILLGPPGTGKTHLAIALGHEAcraGyrVRFTTA--PDLVNeLKEARADGRLERLLKRLA-KVDLLI-LDEL 169
RarA COG2256
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, ...
 63-94 9.53e-05

Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, recombination and repair];


Pssm-ID: 441857 [Multi-domain]  Cd Length: 439  Bit Score: 43.51  E-value: 9.53e-05
                          10        20        30
                  ....*....|....*....|....*....|..
gi 2569152555  63 PSGVLLCGPPGCGKTLLAKAVANEAGVNFISV 94
Cdd:COG2256    49 LSSMILWGPPGTGKTTLARLIANATDAEFVAL 80
44 PHA02544
clamp loader, small subunit; Provisional
 63-279 1.36e-04

clamp loader, small subunit; Provisional


Pssm-ID: 222866 [Multi-domain]  Cd Length: 316  Bit Score: 42.67  E-value: 1.36e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  63 PSGVLLCGPPGCGKTLLAKAVANEAGVNFISVKGpellnmyvgeSERAVRTCFRRARNSA--------PCVIFFDEFDal 134
Cdd:PHA02544   43 PNMLLHSPSPGTGKTTVAKALCNEVGAEVLFVNG----------SDCRIDFVRNRLTRFAstvsltggGKVIIIDEFD-- 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555 135 cpRRSSHDSNGAARVVnqlltemdgIE--SREGVFVLAASNRPDIIDPavLRpGRLDRIMYvGMPAREDRYDILQKLTK- 211
Cdd:PHA02544  111 --RLGLADAQRHLRSF---------MEaySKNCSFIITANNKNGIIEP--LR-SRCRVIDF-GVPTKEEQIEMMKQMIVr 175

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2569152555 212 -NGTKPQLGPDVDLQVIAGLTEGYTgADLSGLVRAAATNALTQHISNGTLEGDIYVTFDDIRAALeKTK 279
Cdd:PHA02544  176 cKGILEAEGVEVDMKVLAALVKKNF-PDFRRTINELQRYASTGKIDAGILSEVTNSDIDDVVEAL-KAK 242
RecA-like_ClpB_Hsp104-like cd19499
Chaperone protein ClpB/Hsp104 subfamily; Bacterial Caseinolytic peptidase B (ClpB) and ...
 57-132 1.64e-04

Chaperone protein ClpB/Hsp104 subfamily; Bacterial Caseinolytic peptidase B (ClpB) and eukaryotic Heat shock protein 104 (Hsp104) are ATP-dependent molecular chaperones and essential proteins of the heat-shock response. ClpB/Hsp104 ATPases, in concert with the DnaK/Hsp70 chaperone system, disaggregate and reactivate aggregated proteins. This RecA-like_ClpB_Hsp104_like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410907 [Multi-domain]  Cd Length: 178  Bit Score: 41.39  E-value: 1.64e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  57 KLGLSAPS---GVLL-CGPPGCGKTLLAKAVA---NEAGVNFISVKGPELLNM------------YVGESERAVRTcfRR 117
Cdd:cd19499    31 RAGLSDPNrpiGSFLfLGPTGVGKTELAKALAellFGDEDNLIRIDMSEYMEKhsvsrligappgYVGYTEGGQLT--EA 108

                          90
                  ....*....|....*
gi 2569152555 118 ARNSAPCVIFFDEFD 132
Cdd:cd19499   109 VRRKPYSVVLLDEIE 123
PRK13342 PRK13342
recombination factor protein RarA; Reviewed
 63-94 1.65e-04

recombination factor protein RarA; Reviewed


Pssm-ID: 237355 [Multi-domain]  Cd Length: 413  Bit Score: 42.76  E-value: 1.65e-04
                          10        20        30
                  ....*....|....*....|....*....|..
gi 2569152555  63 PSGVLLCGPPGCGKTLLAKAVANEAGVNFISV 94
Cdd:PRK13342   36 LSSMILWGPPGTGKTTLARIIAGATDAPFEAL 67
AAA_5 pfam07728
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ...
 65-184 1.75e-04

AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.


Pssm-ID: 400191 [Multi-domain]  Cd Length: 135  Bit Score: 40.74  E-value: 1.75e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  65 GVLLCGPPGCGKTLLAK------------AVANEAGVNFISVKGPelLNMYVGESERaVRTCFRRARNSApCVIFFDEFD 132
Cdd:pfam07728   1 GVLLVGPPGTGKTELAErlaaalsnrpvfYVQLTRDTTEEDLFGR--RNIDPGGASW-VDGPLVRAAREG-EIAVLDEIN 76

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2569152555 133 alcpRRSSHdsngAARVVNQLLTE-----MDGIE----SREGVFVLAASNRPDI----IDPAVLR 184
Cdd:pfam07728  77 ----RANPD----VLNSLLSLLDErrlllPDGGElvkaAPDGFRLIATMNPLDRglneLSPALRS 133
PRK04195 PRK04195
replication factor C large subunit; Provisional
 66-137 2.78e-04

replication factor C large subunit; Provisional


Pssm-ID: 235250 [Multi-domain]  Cd Length: 482  Bit Score: 42.22  E-value: 2.78e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  66 VLLCGPPGCGKTLLAKAVANEAGVNFIsvkgpEL----------LNMYVGESERaVRTCFRRARNsapcVIFFDEFDALC 135
Cdd:PRK04195   42 LLLYGPPGVGKTSLAHALANDYGWEVI-----ELnasdqrtadvIERVAGEAAT-SGSLFGARRK----LILLDEVDGIH 111


                  ..
gi 2569152555 136 PR 137
Cdd:PRK04195  112 GN 113
IS21_help_AAA NF038214
IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was ...
 66-101 4.68e-04

IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was built to hit full-length AAA+ ATPases of IS21 family IS (insertion sequence) elements.


Pssm-ID: 439516  Cd Length: 232  Bit Score: 40.53  E-value: 4.68e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 2569152555  66 VLLCGPPGCGKTLLAKAVANEA-----GVNFISVkgPELLN 101
Cdd:NF038214   93 VLLLGPPGTGKTHLAIALGYAAcrqgyRVRFTTA--ADLVE 131
Mg_chelatase pfam01078
Magnesium chelatase, subunit ChlI; Magnesium-chelatase is a three-component enzyme that ...
 46-82 5.03e-04

Magnesium chelatase, subunit ChlI; Magnesium-chelatase is a three-component enzyme that catalyzes the insertion of Mg2+ into protoporphyrin IX. This is the first unique step in the synthesis of (bacterio)chlorophyll. Due to this, it is thought that Mg-chelatase has an important role in channelling inter- mediates into the (bacterio)chlorophyll branch in response to conditions suitable for photosynthetic growth. ChlI and BchD have molecular weight between 38-42 kDa.


Pssm-ID: 426032 [Multi-domain]  Cd Length: 207  Bit Score: 40.60  E-value: 5.03e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 2569152555  46 LAPVKYPEQLKKLGLSAPSG---VLLCGPPGCGKTLLAKA 82
Cdd:pfam01078   2 LADVKGQEQAKRALEIAAAGghnLLMIGPPGSGKTMLAKR 41
RNA_helicase pfam00910
RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding ...
 66-173 5.15e-04

RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding during viral RNA replication. Members of this family are found in a variety of single stranded RNA viruses.


Pssm-ID: 459992  Cd Length: 102  Bit Score: 38.74  E-value: 5.15e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  66 VLLCGPPGCGKTL----LAKAVANEAGVNFISV----KGPELLNMYVGEseravrtcfrrarnsaPCVIFFDefdaLCPR 137
Cdd:pfam00910   1 IWLYGPPGCGKSTlakyLARALLKKLGLPKDSVysrnPDDDFWDGYTGQ----------------PVVIIDD----FGQN 60

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 2569152555 138 RSSHDSNGAARVVN--QLLTEMDGIESREGVF----VLAASN 173
Cdd:pfam00910  61 PDGPDEAELIRLVSstPYPPPMAALEEKGTPFtskfVIVTSN 102
RecA-like_IQCA1 cd19506
ATPase domain of IQ and AAA domain-containing protein 1 (IQCA1); IQCA1 (also known as dynein ...
 66-175 1.52e-03

ATPase domain of IQ and AAA domain-containing protein 1 (IQCA1); IQCA1 (also known as dynein regulatory complex subunit 11, DRC11 and IQCA) is an ATPase subunit of the nexin-dynein regulatory complex (N-DRC). The 9 + 2 axoneme of most motile cilia and flagella consists of nine outer doublet microtubules arranged in a ring surrounding a central pair of two singlet microtubules. The N-DRC complex maintains alignment between outer doublet microtubules and limits microtubule sliding in motile axonemes. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410914 [Multi-domain]  Cd Length: 160  Bit Score: 38.66  E-value: 1.52e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  66 VLLCGPPGCGKTLLAKAVANEAGVNFISVKGPELLNMYVGES--ERAVRTCFRRARNSAPCVIFFDEFDALCPRR--SSH 141
Cdd:cd19506    29 LLLAGPSGVGKKMLVHAICTETGANLFNLSPSNIAGKYPGKNglQMMLHLVLKVARQLQPSVIWIGDAEKTFYKKvpKTE 108

                          90       100       110
                  ....*....|....*....|....*....|....
gi 2569152555 142 DSNGAARVVNQLLTEMDGIESREGVFVLAASNRP 175
Cdd:cd19506   109 KQLDPKRLKKDLPKILKSLKPEDRVLIVGTTSRP 142
SK cd00464
Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic ...
 68-92 3.15e-03

Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis of aromatic compounds, such as aromatic amino acids, p-aminobenzoic acid, folate and ubiquinone. Shikimate kinase catalyses the phosphorylation of the 3-hydroxyl group of shikimic acid using ATP.


Pssm-ID: 238260 [Multi-domain]  Cd Length: 154  Bit Score: 37.54  E-value: 3.15e-03
                          10        20
                  ....*....|....*....|....*
gi 2569152555  68 LCGPPGCGKTLLAKAVANEAGVNFI 92
Cdd:cd00464     4 LIGMMGAGKTTVGRLLAKALGLPFV 28
ClpX COG1219
ATP-dependent protease Clp, ATPase subunit ClpX [Posttranslational modification, protein ...
 64-106 3.22e-03

ATP-dependent protease Clp, ATPase subunit ClpX [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440832 [Multi-domain]  Cd Length: 409  Bit Score: 38.88  E-value: 3.22e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2569152555  64 SGVLLCGPPGCGKTLLAK----------AVAN-----EAGvnfisvkgpellnmYVGE 106
Cdd:COG1219   110 SNILLIGPTGSGKTLLAQtlarildvpfAIADattltEAG--------------YVGE 153
AAA_16 pfam13191
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the ...
 55-169 4.16e-03

AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.


Pssm-ID: 433025 [Multi-domain]  Cd Length: 167  Bit Score: 37.10  E-value: 4.16e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  55 LKKLGLSAPSGVLLCGPPGCGKTLLAKAV---ANEAGVNFISVKGPELLNMYV---GESERAVRTCFRRARNSAPCVIFF 128
Cdd:pfam13191  16 LDRVRSGRPPSVLLTGEAGTGKTTLLRELlraLERDGGYFLRGKCDENLPYSPlleALTREGLLRQLLDELESSLLEAWR 95

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 2569152555 129 DEFDALCPRRSSHDSNGAARVVNQLLTEMDGIESREGVFVL 169
Cdd:pfam13191  96 AALLEALAPVPELPGDLAERLLDLLLRLLDLLARGERPLVL 136
YifB COG0606
Predicted Mg-chelatase, contains ChlI-like and ATPase domains, YifB family [Posttranslational ...
 66-81 5.45e-03

Predicted Mg-chelatase, contains ChlI-like and ATPase domains, YifB family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440371 [Multi-domain]  Cd Length: 502  Bit Score: 38.10  E-value: 5.45e-03
                          10
                  ....*....|....*.
gi 2569152555  66 VLLCGPPGCGKTLLAK 81
Cdd:COG0606   214 LLMIGPPGSGKTMLAR 229
AAA_33 pfam13671
AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the ...
 66-93 6.38e-03

AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.


Pssm-ID: 463952 [Multi-domain]  Cd Length: 143  Bit Score: 36.52  E-value: 6.38e-03
                          10        20
                  ....*....|....*....|....*...
gi 2569152555  66 VLLCGPPGCGKTLLAKAVANEAGVNFIS 93
Cdd:pfam13671   2 ILLVGLPGSGKSTLARRLLEELGAVRLS 29
Sigma54_activat pfam00158
Sigma-54 interaction domain;
53-94 6.59e-03

Sigma-54 interaction domain;


Pssm-ID: 425491 [Multi-domain]  Cd Length: 168  Bit Score: 36.61  E-value: 6.59e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 2569152555  53 EQLKKLGLSaPSGVLLCGPPGCGKTLLAKAVANE---AGVNFISV 94
Cdd:pfam00158  13 EQAKRVAPT-DAPVLITGESGTGKELFARAIHQLsprADGPFVAV 56
clpX PRK05342
ATP-dependent Clp protease ATP-binding subunit ClpX;
64-106 7.01e-03

ATP-dependent Clp protease ATP-binding subunit ClpX;


Pssm-ID: 235422 [Multi-domain]  Cd Length: 412  Bit Score: 37.83  E-value: 7.01e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2569152555  64 SGVLLCGPPGCGKTLLAK----------AVAN-----EAGvnfisvkgpellnmYVGE 106
Cdd:PRK05342  109 SNILLIGPTGSGKTLLAQtlarildvpfAIADattltEAG--------------YVGE 152
RecA-like_Lon cd19500
lon protease homolog 2 peroxisomal; Lon protease (also known as Lon peptidase) is an ...
 65-134 7.51e-03

lon protease homolog 2 peroxisomal; Lon protease (also known as Lon peptidase) is an evolutionarily conserved ATP-dependent serine protease, present in bacteria and eukaryotic mitochondria and peroxisomes, which mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Lon protease is both an ATP-dependent peptidase and a protein-activated ATPase. This RecA-like Lon domain subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410908 [Multi-domain]  Cd Length: 182  Bit Score: 36.77  E-value: 7.51e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2569152555  65 GVLLC--GPPGCGKTLLAKAVANEAGVNF--ISVKG----PEL---LNMYVGESERAVRTCFRRARNSAPcVIFFDEFDA 133
Cdd:cd19500    37 GPILClvGPPGVGKTSLGKSIARALGRKFvrISLGGvrdeAEIrghRRTYVGAMPGRIIQALKKAGTNNP-VFLLDEIDK 115


                  .
gi 2569152555 134 L 134
Cdd:cd19500   116 I 116
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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