|
Name |
Accession |
Description |
Interval |
E-value |
| Gcl |
COG3960 |
Glyoxylate carboligase [Secondary metabolites biosynthesis, transport and catabolism]; |
2-592 |
0e+00 |
|
Glyoxylate carboligase [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443160 [Multi-domain] Cd Length: 588 Bit Score: 1212.20 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 2 PRMTAAAAAVEILKIEGVSQAFGVPGAAINPFYRELKNVGGIGHTLARHVEGASHMAEGYTRAKAGNIGVCIGTSGPAGT 81
Cdd:COG3960 1 ARMRAVDAAVAVLEKEGVTTAFGVPGAAINPFYSAMRKHGGIRHVLARHVEGASHMAEGYTRAKAGNIGVCIGTSGPAGT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 82 DMITGLYSAIADSIPILCITGQAPVSKLHKEDFQAVDIASIAGPVTKKATTVLEAAQVPGVFQEAFHLMRSGRPGPVLID 161
Cdd:COG3960 81 DMITGLYSASADSIPILCITGQAPRARLHKEDFQAVDIESIAKPVTKWAVTVLEPAQVPRVFQQAFHLMRSGRPGPVLID 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 162 LPIDVQLTEIEFDPETYAPLPVYKPRATRAQAAKALGFLLESQRPLIVAGGGIINADASDLLVEFAELVGVPVISTLMGW 241
Cdd:COG3960 161 LPIDVQMAEIEFDIDTYEPLPVYKPAATRAQIEKALDMLNAAERPLIVAGGGIINADASDLLVEFAELTGVPVIPTLMGW 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 242 GTIPDDHQLAAGMVGVQTAHRYGNATFLESDFVFGIGNRWANRHTGyNLDAYTKGRTFVHVDIEPTQLGKIFAPDFGIAS 321
Cdd:COG3960 241 GSIPDDHPLMAGMVGLQTSHRYGNATLLASDFVLGIGNRWANRHTG-SLDVYTKGRKFVHVDIEPTQIGRVFAPDLGIVS 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 322 DAKAALELFIEIAKELKAEGKLPDFSAWAASAQERKGSLQRRTHFDDIPLKPQRVYEEMNKAFGPETRYVTTIGLSQIAA 401
Cdd:COG3960 320 DAKAALELFVEVARERKAAGKLPDRSAWAAECQERKRTMLRKTHFDNVPIKPQRVYEEMNKAFGRDTRYVSTIGLSQIAA 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 402 AQFLHVYRPRNWINCGQAGPLGWTIPAAIGAATAEPETPIVALSGDYDFQFMIEELAVAAQHKVPYVHVLVNNAYLGLIR 481
Cdd:COG3960 400 AQFLHVYKPRHWINCGQAGPLGWTIPAALGVVAADPDRPVVALSGDYDFQFMIEELAVGAQFKLPYIHVVVNNSYLGLIR 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 482 QAQGGLGINFEVNLEFENINTPELCVYGVDHVKVAEGLGVKAIRVTDPDKLGEAFEEAKKLAQEFQVPVVVEAILERITN 561
Cdd:COG3960 480 QAQRGFDMDYCVQLAFENINAPELGGYGVDHVKVAEGLGCKAIRVTDPEEIAPAFEEAKALMAEHRVPVVVEVILERVTN 559
|
570 580 590
....*....|....*....|....*....|.
gi 2429932465 562 IAMSktVDMSDVTEFEELATEPGHAPTAIRP 592
Cdd:COG3960 560 ISMG--TEIDNVNEFEELAESPADAPTAIAL 588
|
|
| PRK11269 |
PRK11269 |
glyoxylate carboligase; Provisional |
1-593 |
0e+00 |
|
glyoxylate carboligase; Provisional
Pssm-ID: 183066 [Multi-domain] Cd Length: 591 Bit Score: 1201.73 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 1 MPRMTAAAAAVEILKIEGVSQAFGVPGAAINPFYRELKNVGGIGHTLARHVEGASHMAEGYTRAKAGNIGVCIGTSGPAG 80
Cdd:PRK11269 1 MAKMRAVDAAVLVLEKEGVTTAFGVPGAAINPFYSAMRKHGGIRHILARHVEGASHMAEGYTRATAGNIGVCIGTSGPAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 81 TDMITGLYSAIADSIPILCITGQAPVSKLHKEDFQAVDIASIAGPVTKKATTVLEAAQVPGVFQEAFHLMRSGRPGPVLI 160
Cdd:PRK11269 81 TDMITGLYSASADSIPILCITGQAPRARLHKEDFQAVDIESIAKPVTKWAVTVREPALVPRVFQQAFHLMRSGRPGPVLI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 161 DLPIDVQLTEIEFDPETYAPLPVYKPRATRAQAAKALGFLLESQRPLIVAGGGIINADASDLLVEFAELVGVPVISTLMG 240
Cdd:PRK11269 161 DLPFDVQVAEIEFDPDTYEPLPVYKPAATRAQIEKALEMLNAAERPLIVAGGGVINADASDLLVEFAELTGVPVIPTLMG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 241 WGTIPDDHQLAAGMVGVQTAHRYGNATFLESDFVFGIGNRWANRHTGyNLDAYTKGRTFVHVDIEPTQLGKIFAPDFGIA 320
Cdd:PRK11269 241 WGAIPDDHPLMAGMVGLQTSHRYGNATLLASDFVLGIGNRWANRHTG-SVEVYTKGRKFVHVDIEPTQIGRVFGPDLGIV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 321 SDAKAALELFIEIAKELKAEGKLPDFSAWAASAQERKGSLQRRTHFDDIPLKPQRVYEEMNKAFGPETRYVTTIGLSQIA 400
Cdd:PRK11269 320 SDAKAALELLVEVAREWKAAGRLPDRSAWVADCQERKRTLLRKTHFDNVPIKPQRVYEEMNKAFGRDTCYVSTIGLSQIA 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 401 AAQFLHVYRPRNWINCGQAGPLGWTIPAAIGAATAEPETPIVALSGDYDFQFMIEELAVAAQHKVPYVHVLVNNAYLGLI 480
Cdd:PRK11269 400 AAQFLHVYKPRHWINCGQAGPLGWTIPAALGVRAADPDRNVVALSGDYDFQFLIEELAVGAQFNLPYIHVLVNNAYLGLI 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 481 RQAQGGLGINFEVNLEFENINTPELCVYGVDHVKVAEGLGVKAIRVTDPDKLGEAFEEAKKLAQEFQVPVVVEAILERIT 560
Cdd:PRK11269 480 RQAQRAFDMDYCVQLAFENINSPELNGYGVDHVKVAEGLGCKAIRVFKPEDIAPALEQAKALMAEFRVPVVVEVILERVT 559
|
570 580 590
....*....|....*....|....*....|...
gi 2429932465 561 NIAMSKTVDmsDVTEFEELATEPGHAPTAIRPL 593
Cdd:PRK11269 560 NISMGTEID--AVNEFEELADNAADAPTAIMLL 590
|
|
| glyox_carbo_lig |
TIGR01504 |
glyoxylate carboligase; Glyoxylate carboligase, also called tartronate-semialdehyde synthase, ... |
3-591 |
0e+00 |
|
glyoxylate carboligase; Glyoxylate carboligase, also called tartronate-semialdehyde synthase, releases CO2 while synthesizing a single molecule of tartronate semialdehyde from two molecules of glyoxylate. It is a thiamine pyrophosphate-dependent enzyme, closely related in sequence to the large subunit of acetolactate synthase. In the D-glycerate pathway, part of allantoin degradation in the Enterobacteriaceae, tartronate semialdehyde is converted to D-glycerate and then 3-phosphoglycerate, a product of glycolysis and entry point in the general metabolism.
Pssm-ID: 213633 [Multi-domain] Cd Length: 588 Bit Score: 1039.15 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 3 RMTAAAAAVEILKIEGVSQAFGVPGAAINPFYRELKNVGGIGHTLARHVEGASHMAEGYTRAKAGNIGVCIGTSGPAGTD 82
Cdd:TIGR01504 2 RMRAVDAAVYVLEKEGITTAFGVPGAAINPFYSALKAHGGIRHILARHVEGASHMAEGYTRATAGNIGVCIGTSGPAGTD 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 83 MITGLYSAIADSIPILCITGQAPVSKLHKEDFQAVDIASIAGPVTKKATTVLEAAQVPGVFQEAFHLMRSGRPGPVLIDL 162
Cdd:TIGR01504 82 MITGLYSASADSIPILCITGQAPRARLHKEDFQAVDIAAIAKPVSKMAVTVREAALVPRVLQQAFHLMRSGRPGPVLIDL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 163 PIDVQLTEIEFDPETYAPLPVYKPRATRAQAAKALGFLLESQRPLIVAGGGIINADASDLLVEFAELVGVPVISTLMGWG 242
Cdd:TIGR01504 162 PFDVQVAEIEFDPDTYEPLPVYKPAATRAQIEKAVEMLNAAERPLIVAGGGVINADAADLLQEFAELTGVPVIPTLMGWG 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 243 TIPDDHQLAAGMVGVQTAHRYGNATFLESDFVFGIGNRWANRHTGyNLDAYTKGRTFVHVDIEPTQLGKIFAPDFGIASD 322
Cdd:TIGR01504 242 CIPDDHELMAGMVGLQTSHRYGNATLLESDFVFGIGNRWANRHTG-SVDVYTEGRKFVHVDIEPTQIGRVFAPDLGIVSD 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 323 AKAALELFIEIAKELKAEGKLPDFSAWAASAQERKGSLQRRTHFDDIPLKPQRVYEEMNKAFGPETRYVTTIGLSQIAAA 402
Cdd:TIGR01504 321 AKAALKLLVEVAQELKKAGRLPDRSEWAADCQQRKRTLLRKTHFDNVPVKPQRVYEEMNKAFGRDVCYVTTIGLSQIAGA 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 403 QFLHVYRPRNWINCGQAGPLGWTIPAAIGAATAEPETPIVALSGDYDFQFMIEELAVAAQHKVPYVHVLVNNAYLGLIRQ 482
Cdd:TIGR01504 401 QMLHVYKPRHWINCGQAGPLGWTIPAALGVCAADPKRNVVALSGDYDFQFMIEELAVGAQHNIPYIHVLVNNAYLGLIRQ 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 483 AQGGLGINFEVNLEFENINTPELCVYGVDHVKVAEGLGVKAIRVTDPDKLGEAFEEAKKLAQEFQVPVVVEAILERITNI 562
Cdd:TIGR01504 481 AQRAFDMDYCVQLAFENINSSEVNGYGVDHVKVAEGLGCKAIRVFKPEEIAPAFEQAKALMAEHRVPVVVEVILERVTNI 560
|
570 580
....*....|....*....|....*....
gi 2429932465 563 AMSKtvDMSDVTEFEELATEPGHAPTAIR 591
Cdd:TIGR01504 561 SMGS--EIDNVVEFEDLADNAADAPTATC 587
|
|
| IlvB |
COG0028 |
Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme [Amino ... |
2-570 |
4.37e-179 |
|
Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme [Amino acid transport and metabolism, Coenzyme transport and metabolism]; Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 439799 [Multi-domain] Cd Length: 548 Bit Score: 517.41 E-value: 4.37e-179
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 2 PRMTAAAAAVEILKIEGVSQAFGVPGAAINPFYRELKNVGGIGHTLARHVEGASHMAEGYTRAKaGNIGVCIGTSGPAGT 81
Cdd:COG0028 1 MKMTGADALVEALEAEGVETVFGVPGGAILPLYDALRRQSGIRHILVRHEQGAAFMADGYARAT-GKPGVCLVTSGPGAT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 82 DMITGLYSAIADSIPILCITGQAPVSKLHKEDFQAVDIASIAGPVTKKATTVLEAAQVPGVFQEAFHLMRSGRPGPVLID 161
Cdd:COG0028 80 NLVTGLADAYMDSVPVLAITGQVPTSLIGRGAFQEVDQVGLFRPITKWSYLVTDPEDLPEVLRRAFRIATSGRPGPVVLD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 162 LPIDVQLTEIEFDPETyAPLPVYKPRAT--RAQAAKALGFLLESQRPLIVAGGGIINADASDLLVEFAELVGVPVISTLM 239
Cdd:COG0028 160 IPKDVQAAEAEEEPAP-PELRGYRPRPApdPEAIEEAAELLAAAKRPVILAGGGARRAGAAEELRALAERLGAPVVTTLM 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 240 GWGTIPDDHQLAAGMVGVQtAHRYGNATFLESDFVFGIGNRWANRHTGyNLDAYTKGRTFVHVDIEPTQLGKIFAPDFGI 319
Cdd:COG0028 239 GKGAFPEDHPLYLGMLGMH-GTPAANEALAEADLVLAVGARFDDRVTG-NWDEFAPDAKIIHIDIDPAEIGKNYPVDLPI 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 320 ASDAKAALElfiEIAKELKAegKLPDFSAWAASAQERKGSLQRRTHFDDIPLKPQRVYEEMNKAFGPETRYVTTIGLSQI 399
Cdd:COG0028 317 VGDAKAVLA---ALLEALEP--RADDRAAWLARIAAWRAEYLAAYAADDGPIKPQRVIAALREALPDDAIVVTDVGQHQM 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 400 AAAQFLHVYRPRNWINCGQAGPLGWTIPAAIGAATAEPETPIVALSGDYDFQFMIEELAVAAQHKVPYVHVLVNNAYLGL 479
Cdd:COG0028 392 WAARYLRFRRPRRFLTSGGLGTMGYGLPAAIGAKLARPDRPVVAITGDGGFQMNLQELATAVRYGLPVKVVVLNNGGLGM 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 480 IRQAQgglginfevnLEFENINTPELCVYGVDHVKVAEGLGVKAIRVTDPDKLGEAFEEAkkLAQEfqVPVVVEAILERI 559
Cdd:COG0028 472 VRQWQ----------ELFYGGRYSGTDLPNPDFAKLAEAFGAKGERVETPEELEAALEEA--LASD--GPALIDVRVDPE 537
|
570
....*....|.
gi 2429932465 560 TNIAMSKTVDM 570
Cdd:COG0028 538 ENPPGATLDEM 548
|
|
| acolac_lg |
TIGR00118 |
acetolactate synthase, large subunit, biosynthetic type; Two groups of proteins form ... |
4-553 |
1.31e-154 |
|
acetolactate synthase, large subunit, biosynthetic type; Two groups of proteins form acetolactate from two molecules of pyruvate. The type of acetolactate synthase described in this model also catalyzes the formation of acetohydroxybutyrate from pyruvate and 2-oxobutyrate, an early step in the branched chain amino acid biosynthesis; it is therefore also termed acetohydroxyacid synthase. In bacteria, this catalytic chain is associated with a smaller regulatory chain in an alpha2/beta2 heterotetramer. Acetolactate synthase is a thiamine pyrophosphate enzyme. In this type, FAD and Mg++ are also found. Several isozymes of this enzyme are found in E. coli K12, one of which contains a frameshift in the large subunit gene and is not expressed. [Amino acid biosynthesis, Pyruvate family]
Pssm-ID: 272915 [Multi-domain] Cd Length: 558 Bit Score: 455.34 E-value: 1.31e-154
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 4 MTAAAAAVEILKIEGVSQAFGVPGAAINPFYRELKNVGGIGHTLARHVEGASHMAEGYTRAkAGNIGVCIGTSGPAGTDM 83
Cdd:TIGR00118 1 MSGAEAIIESLKDEGVKTVFGYPGGAILPIYDALYNDSGIEHILVRHEQGAAHAADGYARA-SGKVGVVLVTSGPGATNL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 84 ITGLYSAIADSIPILCITGQAPVSKLHKEDFQAVDIASIAGPVTKKATTVLEAAQVPGVFQEAFHLMRSGRPGPVLIDLP 163
Cdd:TIGR00118 80 VTGIATAYMDSIPMVVFTGQVPTSLIGSDAFQEADILGITMPITKHSFQVKSAEDIPRIIKEAFHIATTGRPGPVLVDLP 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 164 IDVQLTEIEFDPETYAPLPVYKPRAT--RAQAAKALGFLLESQRPLIVAGGGIINADASDLLVEFAELVGVPVISTLMGW 241
Cdd:TIGR00118 160 KDVTTAEIEYPYPEKVNLPGYRPTVKghPLQIKKAAELINLAKKPVILVGGGVIIAGASEELKELAERIQIPVTTTLMGL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 242 GTIPDDHQLAAGMVGVQtAHRYGNATFLESDFVFGIGNRWANRHTGyNLDAYTKGRTFVHVDIEPTQLGKIFAPDFGIAS 321
Cdd:TIGR00118 240 GSFPEDHPLSLGMLGMH-GTKTANLAVHECDLIIAVGARFDDRVTG-NLAKFAPNAKIIHIDIDPAEIGKNVRVDIPIVG 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 322 DAKAALELFIEIAKELKAegklPDFSAWAASAQERKGSLQRRTHFDDIPLKPQRVYEEMNKaFGPETRYVTT-IGLSQIA 400
Cdd:TIGR00118 318 DARNVLEELLKKLFELKE----RKESAWLEQINKWKKEYPLKMDYTEEGIKPQQVIEELSR-VTKDEAIVTTdVGQHQMW 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 401 AAQFLHVYRPRNWINCGQAGPLGWTIPAAIGAATAEPETPIVALSGDYDFQFMIEELAVAAQHKVPYVHVLVNNAYLGLI 480
Cdd:TIGR00118 393 AAQFYPFRKPRRFITSGGLGTMGFGLPAAIGAKVAKPESTVICITGDGSFQMNLQELSTAVQYDIPVKILILNNRYLGMV 472
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2429932465 481 RQAQgglginfevNLEFENINTPELCVYGVDHVKVAEGLGVKAIRVTDPDKLGEAFEEAKklaqEFQVPVVVE 553
Cdd:TIGR00118 473 RQWQ---------ELFYEERYSHTHMGSLPDFVKLAEAYGIKGIRIEKPEELDEKLKEAL----SSNEPVLLD 532
|
|
| PRK06048 |
PRK06048 |
acetolactate synthase large subunit; |
1-562 |
1.31e-136 |
|
acetolactate synthase large subunit;
Pssm-ID: 180368 [Multi-domain] Cd Length: 561 Bit Score: 409.55 E-value: 1.31e-136
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 1 MPRMTAAAAAVEILKIEGVSQAFGVPGAAINPFYRELKNvGGIGHTLARHVEGASHMAEGYTRAkAGNIGVCIGTSGPAG 80
Cdd:PRK06048 5 TEKMTGARAIIKCLEKEGVEVIFGYPGGAIIPVYDELYD-SDLRHILVRHEQAAAHAADGYARA-TGKVGVCVATSGPGA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 81 TDMITGLYSAIADSIPILCITGQAPVSKLHKEDFQAVDIASIAGPVTKKATTVLEAAQVPGVFQEAFHLMRSGRPGPVLI 160
Cdd:PRK06048 83 TNLVTGIATAYMDSVPIVALTGQVPRSMIGNDAFQEADITGITMPITKHNYLVQDAKDLPRIIKEAFHIASTGRPGPVLI 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 161 DLPIDVQLTEIEFDPETYAPLPVYKP--RATRAQAAKALGFLLESQRPLIVAGGGIINADASDLLVEFAELVGVPVISTL 238
Cdd:PRK06048 163 DLPKDVTTAEIDFDYPDKVELRGYKPtyKGNPQQIKRAAELIMKAERPIIYAGGGVISSNASEELVELAETIPAPVTTTL 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 239 MGWGTIPDDHQLAAGMVGVQTAhRYGNATFLESDFVFGIGNRWANRHTGyNLDAYTKGRTFVHVDIEPTQLGKIFAPDFG 318
Cdd:PRK06048 243 MGIGAIPTEHPLSLGMLGMHGT-KYANYAIQESDLIIAVGARFDDRVTG-KLASFAPNAKIIHIDIDPAEISKNVKVDVP 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 319 IASDAKAALelfieiaKELKAEGKLPDFSAWAASAQERKGSLQRRTHFDDIPLKPQRVYEEMNKAFgPETRYVTTIGLSQ 398
Cdd:PRK06048 321 IVGDAKQVL-------KSLIKYVQYCDRKEWLDKINQWKKEYPLKYKEREDVIKPQYVIEQIYELC-PDAIIVTEVGQHQ 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 399 IAAAQFLHVYRPRNWINCGQAGPLGWTIPAAIGAATAEPETPIVALSGDYDFQFMIEELAVAAQHKVPYVHVLVNNAYLG 478
Cdd:PRK06048 393 MWAAQYFKYKYPRTFITSGGLGTMGYGFPAAIGAKVGKPDKTVIDIAGDGSFQMNSQELATAVQNDIPVIVAILNNGYLG 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 479 LIRQAQgglginfevNLEFENINTPELCVYGVDHVKVAEGLGVKAIRVTDPDKLGEAFEEAKklaqEFQVPVVVEAILER 558
Cdd:PRK06048 473 MVRQWQ---------ELFYDKRYSHTCIKGSVDFVKLAEAYGALGLRVEKPSEVRPAIEEAV----ASDRPVVIDFIVEC 539
|
....
gi 2429932465 559 ITNI 562
Cdd:PRK06048 540 EENV 543
|
|
| TPP_Gcl |
cd02006 |
Thiamine pyrophosphate (TPP) family, Gcl subfamily, TPP-binding module; composed of proteins ... |
364-565 |
1.23e-134 |
|
Thiamine pyrophosphate (TPP) family, Gcl subfamily, TPP-binding module; composed of proteins similar to Escherichia coli glyoxylate carboligase (Gcl). E. coli glyoxylate carboligase, plays a key role in glyoxylate metabolism where it catalyzes the condensation of two molecules of glyoxylate to give tartronic semialdehyde and carbon dioxide. This enzyme requires TPP, magnesium ion and FAD as cofactors.
Pssm-ID: 238964 [Multi-domain] Cd Length: 202 Bit Score: 390.87 E-value: 1.23e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 364 THFDDIPLKPQRVYEEMNKAFGPETRYVTTIGLSQIAAAQFLHVYRPRNWINCGQAGPLGWTIPAAIGAATAEPETPIVA 443
Cdd:cd02006 1 THFDDVPIKPQRVYEEMNKAFGRDVRYVTTIGLSQIAGAQMLHVYKPRHWINCGQAGPLGWTVPAALGVAAADPDRQVVA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 444 LSGDYDFQFMIEELAVAAQHKVPYVHVLVNNAYLGLIRQAQGGLGINFEVNLEFENINTPELCVYGVDHVKVAEGLGVKA 523
Cdd:cd02006 81 LSGDYDFQFMIEELAVGAQHRIPYIHVLVNNAYLGLIRQAQRAFDMDYQVNLAFENINSSELGGYGVDHVKVAEGLGCKA 160
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 2429932465 524 IRVTDPDKLGEAFEEAKKLAQEFQVPVVVEAILERITNIAMS 565
Cdd:cd02006 161 IRVTKPEELAAAFEQAKKLMAEHRVPVVVEAILERVTNISMG 202
|
|
| PRK06276 |
PRK06276 |
acetolactate synthase large subunit; |
4-553 |
5.65e-132 |
|
acetolactate synthase large subunit;
Pssm-ID: 235766 [Multi-domain] Cd Length: 586 Bit Score: 398.36 E-value: 5.65e-132
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 4 MTAAAAAVEILKIEGVSQAFGVPGAAINPFYRELKNvGGIGHTLARHVEGASHMAEGYTRAKaGNIGVCIGTSGPAGTDM 83
Cdd:PRK06276 1 MKGAEAIIKALEAEGVKIIFGYPGGALLPFYDALYD-SDLIHILTRHEQAAAHAADGYARAS-GKVGVCVATSGPGATNL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 84 ITGLYSAIADSIPILCITGQAPVSKLHKEDFQAVDIASIAGPVTKKATTVLEAAQVPGVFQEAFHLMRSGRPGPVLIDLP 163
Cdd:PRK06276 79 VTGIATAYADSSPVIALTGQVPTKLIGNDAFQEIDALGIFMPITKHNFQIKKPEEIPEIFRAAFEIAKTGRPGPVHIDLP 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 164 IDVQltEIEFDPETYA-----PLPVYKP--RATRAQAAKALGFLLESQRPLIVAGGGIINADASDLLVEFAELVGVPVIS 236
Cdd:PRK06276 159 KDVQ--EGELDLEKYPipakiDLPGYKPttFGHPLQIKKAAELIAEAERPVILAGGGVIISGASEELIELSELVKIPVCT 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 237 TLMGWGTIPDDHQLAAGMVGVQtAHRYGNATFLESDFVFGIGNRWANRHTGyNLDAYTKGRTFVHVDIEPTQLGKIFAPD 316
Cdd:PRK06276 237 TLMGKGAFPEDHPLALGMVGMH-GTKAANYSVTESDVLIAIGCRFSDRTTG-DISSFAPNAKIIHIDIDPAEIGKNVRVD 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 317 FGIASDAKAALElfiEIAKELKAEgKLPDFSAWAASAQERKGSLQRRTHFDDIPLKPQRVYEEMNKAFGP-----ETRYV 391
Cdd:PRK06276 315 VPIVGDAKNVLR---DLLAELMKK-EIKNKSEWLERVKKLKKESIPRMDFDDKPIKPQRVIKELMEVLREidpskNTIIT 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 392 TTIGLSQIAAAQFLHVYRPRNWINCGQAGPLGWTIPAAIGAATAEPETPIVALSGDYDFQFMIEELAVAAQHKVPYVHVL 471
Cdd:PRK06276 391 TDVGQNQMWMAHFFKTSAPRSFISSGGLGTMGFGFPAAIGAKVAKPDANVIAITGDGGFLMNSQELATIAEYDIPVVICI 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 472 VNNAYLGLIRQAQGGL--GINFEVNLEfeniNTPelcvygvDHVKVAEGLGVKAIRVTDPDKLGEAFEEAKKLAQEFQVP 549
Cdd:PRK06276 471 FDNRTLGMVYQWQNLYygKRQSEVHLG----ETP-------DFVKLAESYGVKADRVEKPDEIKEALKEAIKSGEPYLLD 539
|
....
gi 2429932465 550 VVVE 553
Cdd:PRK06276 540 IIID 543
|
|
| PRK07789 |
PRK07789 |
acetolactate synthase 1 catalytic subunit; Validated |
3-555 |
2.85e-123 |
|
acetolactate synthase 1 catalytic subunit; Validated
Pssm-ID: 236098 [Multi-domain] Cd Length: 612 Bit Score: 376.63 E-value: 2.85e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 3 RMTAAAAAVEILKIEGVSQAFGVPGAAINPFYRELKNVGGIGHTLARHVEGASHMAEGYTRAkAGNIGVCIGTSGPAGTD 82
Cdd:PRK07789 30 RMTGAQAVVRSLEELGVDVVFGIPGGAILPVYDPLFDSTKVRHVLVRHEQGAGHAAEGYAQA-TGRVGVCMATSGPGATN 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 83 MITGLYSAIADSIPILCITGQAPVSKLHKEDFQAVDIASIAGPVTKKATTVLEAAQVPGVFQEAFHLMRSGRPGPVLIDL 162
Cdd:PRK07789 109 LVTPIADANMDSVPVVAITGQVGRGLIGTDAFQEADIVGITMPITKHNFLVTDADDIPRVIAEAFHIASTGRPGPVLVDI 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 163 PIDVQLTEIEFD-PETYApLPVYKPrATRA---QAAKALGFLLESQRPLIVAGGGIINADASDLLVEFAELVGVPVISTL 238
Cdd:PRK07789 189 PKDALQAQTTFSwPPRMD-LPGYRP-VTKPhgkQIREAAKLIAAARRPVLYVGGGVIRAEASAELRELAELTGIPVVTTL 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 239 MGWGTIPDDHQLAAGMVGVqtahrYGN----ATFLESDFVFGIGNRWANRHTGyNLDAYTKGRTFVHVDIEPTQLGKIFA 314
Cdd:PRK07789 267 MARGAFPDSHPQHLGMPGM-----HGTvaavAALQRSDLLIALGARFDDRVTG-KLDSFAPDAKVIHADIDPAEIGKNRH 340
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 315 PDFGIASDAKAALELFIEIAKELKAEGKLPDFSAWAASAQerkgSLQRR-----THFDDIPLKPQRVYEEMNKAFGPETR 389
Cdd:PRK07789 341 ADVPIVGDVKEVIAELIAALRAEHAAGGKPDLTAWWAYLD----GWRETyplgyDEPSDGSLAPQYVIERLGEIAGPDAI 416
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 390 YVTTIGLSQIAAAQFLHVYRPRNWINCGQAGPLGWTIPAAIGAATAEPETPIVALSGDYDFQFMIEELAVAAQHKVPYVH 469
Cdd:PRK07789 417 YVAGVGQHQMWAAQFIDYEKPRTWLNSGGLGTMGYAVPAAMGAKVGRPDKEVWAIDGDGCFQMTNQELATCAIEGIPIKV 496
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 470 VLVNNAYLGLIRQAQgglGINFEVNLEFENINTPELCVygVDHVKVAEGLGVKAIRVTDPDKLGEAFEEAKKLAqefQVP 549
Cdd:PRK07789 497 ALINNGNLGMVRQWQ---TLFYEERYSNTDLHTHSHRI--PDFVKLAEAYGCVGLRCEREEDVDAVIEKARAIN---DRP 568
|
....*.
gi 2429932465 550 VVVEAI 555
Cdd:PRK07789 569 VVIDFV 574
|
|
| PRK08527 |
PRK08527 |
acetolactate synthase large subunit; |
3-562 |
1.15e-121 |
|
acetolactate synthase large subunit;
Pssm-ID: 181458 [Multi-domain] Cd Length: 563 Bit Score: 370.97 E-value: 1.15e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 3 RMTAAAAAVEILKIEGVSQAFGVPGAAINPFYRELKNVGGIGHTLARHVEGASHMAEGYTRAkAGNIGVCIGTSGPAGTD 82
Cdd:PRK08527 2 KLSGSQMVCEALKEEGVKVVFGYPGGAILNIYDEIYKQNYFKHILTRHEQAAVHAADGYARA-SGKVGVAIVTSGPGFTN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 83 MITGLYSAIADSIPILCITGQAPVSKLHKEDFQAVDIASIAGPVTKKATTVLEAAQVPGVFQEAFHLMRSGRPGPVLIDL 162
Cdd:PRK08527 81 AVTGLATAYMDSIPLVLISGQVPNSLIGTDAFQEIDAVGISRPCVKHNYLVKSIEELPRILKEAFYIARSGRPGPVHIDI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 163 PIDVQLTEIEFDPETYAPLPVYKP--RATRAQAAKALGFLLESQRPLIVAGGGIINADASDLLVEFAELVGVPVISTLMG 240
Cdd:PRK08527 161 PKDVTATLGEFEYPKEISLKTYKPtyKGNSRQIKKAAEAIKEAKKPLFYLGGGAILSNASEEIRELVKKTGIPAVETLMA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 241 WGTIPDDHQLAAGMVGVQTAHRyGNATFLESDFVFGIGNRWANRHTGyNLDAYTKGRTFVHVDIEPTQLGKIFAPDFGIA 320
Cdd:PRK08527 241 RGVLRSDDPLLLGMLGMHGSYA-ANMAMSECDLLISLGARFDDRVTG-KLSEFAKHAKIIHVDIDPSSISKIVNADYPIV 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 321 SDAKAALELFIEIAKELKAEgklpDFSAWAASAQERKGSLQRRTHFDDIPLKPQRVYEEMNKAFGPETRYVTTIGLSQIA 400
Cdd:PRK08527 319 GDLKNVLKEMLEELKEENPT----TYKEWREILKRYNELHPLSYEDSDEVLKPQWVIERVGELLGDDAIISTDVGQHQMW 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 401 AAQFLHVYRPRNWINCGQAGPLGWTIPAAIGAATAEPETPIVALSGDYDFQFMIEELAVAAQHKVPYVHVLVNNAYLGLI 480
Cdd:PRK08527 395 VAQFYPFNYPRQLATSGGLGTMGYGLPAALGAKLAVPDKVVINFTGDGSILMNIQELMTAVEYKIPVINIILNNNFLGMV 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 481 RQAQgglgiNF-------EVNLEFEnintPelcvygvDHVKVAEGLGVKAIRVTDPDKlgeaFEEAKKLAQEFQVPVVVE 553
Cdd:PRK08527 475 RQWQ-----TFfyeerysETDLSTQ----P-------DFVKLAESFGGIGFRVTTKEE----FDKALKEALESDKVALID 534
|
....*....
gi 2429932465 554 AILERITNI 562
Cdd:PRK08527 535 VKIDRFENV 543
|
|
| PRK07418 |
PRK07418 |
acetolactate synthase large subunit; |
3-561 |
1.58e-119 |
|
acetolactate synthase large subunit;
Pssm-ID: 236014 [Multi-domain] Cd Length: 616 Bit Score: 367.07 E-value: 1.58e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 3 RMTAAAAAVEILKIEGVSQAFGVPGAAINPFYRELKNV---GGIGHTLARHVEGASHMAEGYTRAkAGNIGVCIGTSGPA 79
Cdd:PRK07418 18 RATGAYALMDSLKRHGVKHIFGYPGGAILPIYDELYKAeaeGWLKHILVRHEQGAAHAADGYARA-TGKVGVCFGTSGPG 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 80 GTDMITGLYSAIADSIPILCITGQAPVSKLHKEDFQAVDIASIAGPVTKKATTVLEAAQVPGVFQEAFHLMRSGRPGPVL 159
Cdd:PRK07418 97 ATNLVTGIATAQMDSVPMVVITGQVPRPAIGTDAFQETDIFGITLPIVKHSYVVRDPSDMARIVAEAFHIASSGRPGPVL 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 160 IDLPIDVQLTEIEFDPetYAP----LPVYKP--RATRAQAAKALGFLLESQRPLIVAGGGIINADASDLLVEFAELVGVP 233
Cdd:PRK07418 177 IDIPKDVGQEEFDYVP--VEPgsvkPPGYRPtvKGNPRQINAALKLIEEAERPLLYVGGGAISAGAHAELKELAERFQIP 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 234 VISTLMGWGTIPDDHQLAAGMVGVQ-TAhrYGNATFLESDFVFGIGNRWANRHTGyNLDAYTKGRTFVHVDIEPTQLGKI 312
Cdd:PRK07418 255 VTTTLMGKGAFDEHHPLSVGMLGMHgTA--YANFAVTECDLLIAVGARFDDRVTG-KLDEFASRAKVIHIDIDPAEVGKN 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 313 FAPDFGIASDAKAALELFIEIAKELKAEgklPDFSAWAASAQERKGSLQRRTHFDDIPLKPQRVYEEMNKaFGPETRYVT 392
Cdd:PRK07418 332 RRPDVPIVGDVRKVLVKLLERSLEPTTP---PRTQAWLERINRWKQDYPLVVPPYEGEIYPQEVLLAVRD-LAPDAYYTT 407
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 393 TIGLSQIAAAQFLHvYRPRNWINCGQAGPLGWTIPAAIGAATAEPETPIVALSGDYDFQFMIEELAVAAQHKVPYVHVLV 472
Cdd:PRK07418 408 DVGQHQMWAAQFLR-NGPRRWISSAGLGTMGFGMPAAMGVKVALPDEEVICIAGDASFLMNIQELGTLAQYGINVKTVII 486
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 473 NNAYLGLIRQAQGGLginFEVNLEFENINTPElcvygVDHVKVAEGLGVKAIRVTDPDKLGEAFEEAkkLAqeFQVPVVV 552
Cdd:PRK07418 487 NNGWQGMVRQWQESF---YGERYSASNMEPGM-----PDFVKLAEAFGVKGMVISERDQLKDAIAEA--LA--HDGPVLI 554
|
....*....
gi 2429932465 553 EAILERITN 561
Cdd:PRK07418 555 DVHVRRDEN 563
|
|
| PRK06725 |
PRK06725 |
acetolactate synthase large subunit; |
4-562 |
8.44e-117 |
|
acetolactate synthase large subunit;
Pssm-ID: 180672 [Multi-domain] Cd Length: 570 Bit Score: 358.90 E-value: 8.44e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 4 MTAAAAAVEILKIEGVSQAFGVPGAAINPFYRELKNvGGIGHTLARHVEGASHMAEGYTRAkAGNIGVCIGTSGPAGTDM 83
Cdd:PRK06725 15 VTGAGHVIQCLKKLGVTTVFGYPGGAILPVYDALYE-SGLKHILTRHEQAAIHAAEGYARA-SGKVGVVFATSGPGATNL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 84 ITGLYSAIADSIPILCITGQAPVSKLHKEDFQAVDIASIAGPVTKKATTVLEAAQVPGVFQEAFHLMRSGRPGPVLIDLP 163
Cdd:PRK06725 93 VTGLADAYMDSIPLVVITGQVATPLIGKDGFQEADVVGITVPVTKHNYQVRDVNQLSRIVQEAFYIAESGRPGPVLIDIP 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 164 IDVQLTEIEFDPETYAPLPVYKPRATR-----AQAAKALGfllESQRPLIVAGGGIINADASDLLVEFAELVGVPVISTL 238
Cdd:PRK06725 173 KDVQNEKVTSFYNEVVEIPGYKPEPRPdsmklREVAKAIS---KAKRPLLYIGGGVIHSGGSEELIEFARENRIPVVSTL 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 239 MGWGTIPDDHQLAAGMVGVQTAHRyGNATFLESDFVFGIGNRWANRHTGyNLDAYTKGRTFVHVDIEPTQLGKIFAPDFG 318
Cdd:PRK06725 250 MGLGAYPPGDPLFLGMLGMHGTYA-ANMAVTECDLLLALGVRFDDRVTG-KLELFSPHSKKVHIDIDPSEFHKNVAVEYP 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 319 IASDAKAALELFIEIAKELKAEGKLPDFSAWaaSAQERKGSLQRRTHfddipLKPQRVYEEMNKAFGPETRYVTTIGLSQ 398
Cdd:PRK06725 328 VVGDVKKALHMLLHMSIHTQTDEWLQKVKTW--KEEYPLSYKQKESE-----LKPQHVINLVSELTNGEAIVTTEVGQHQ 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 399 IAAAQFLHVYRPRNWINCGQAGPLGWTIPAAIGAATAEPETPIVALSGDYDFQFMIEELAVAAQHKVPYVHVLVNNAYLG 478
Cdd:PRK06725 401 MWAAHFYKAKNPRTFLTSGGLGTMGFGFPAAIGAQLAKEEELVICIAGDASFQMNIQELQTIAENNIPVKVFIINNKFLG 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 479 LIRQAQgglGINFEVNLEFENINTPelcvygvDHVKVAEGLGVKAIRVTDPDKLGEAFEEAkkLAQEFqvPVVVEAILER 558
Cdd:PRK06725 481 MVRQWQ---EMFYENRLSESKIGSP-------DFVKVAEAYGVKGLRATNSTEAKQVMLEA--FAHEG--PVVVDFCVEE 546
|
....
gi 2429932465 559 ITNI 562
Cdd:PRK06725 547 GENV 550
|
|
| PRK09107 |
PRK09107 |
acetolactate synthase 3 catalytic subunit; Validated |
1-538 |
1.33e-116 |
|
acetolactate synthase 3 catalytic subunit; Validated
Pssm-ID: 236380 [Multi-domain] Cd Length: 595 Bit Score: 359.02 E-value: 1.33e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 1 MPR-MTAAAAAVEILKIEGVSQAFGVPGAAINPFYRELKNVGGIGHTLARHVEGASHMAEGYTRAkAGNIGVCIGTSGPA 79
Cdd:PRK09107 7 MPRqMTGAEMVVQALKDQGVEHIFGYPGGAVLPIYDEIFQQDDIQHILVRHEQGAGHAAEGYARS-TGKPGVVLVTSGPG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 80 GTDMITGLYSAIADSIPILCITGQAPVSKLHKEDFQAVDIASIAGPVTKKATTVLEAAQVPGVFQEAFHLMRSGRPGPVL 159
Cdd:PRK09107 86 ATNAVTPLQDALMDSIPLVCITGQVPTHLIGSDAFQECDTVGITRPCTKHNWLVKDVNDLARVIHEAFHVATSGRPGPVV 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 160 IDLPIDVQL-TEIEFDPETYAPLPVYKPR--ATRAQAAKALGFLLESQRPLIVAGGGIINA--DASDLLVEFAELVGVPV 234
Cdd:PRK09107 166 VDIPKDVQFaTGTYTPPQKAPVHVSYQPKvkGDAEAITEAVELLANAKRPVIYSGGGVINSgpEASRLLRELVELTGFPI 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 235 ISTLMGWGTIPDDHQLAAGMVGVQTAHRyGNATFLESDFVFGIGNRWANRHTGyNLDAYTKGRTFVHVDIEPTQLGKIFA 314
Cdd:PRK09107 246 TSTLMGLGAYPASGKNWLGMLGMHGTYE-ANMAMHDCDVMLCVGARFDDRITG-RLDAFSPNSKKIHIDIDPSSINKNVR 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 315 PDFGIASDAKAALElfiEIAKELKAEGKLPDFSA----WAASAQERKGSLQRRTHFDDIpLKPQRVYEEMNKAFGPETRY 390
Cdd:PRK09107 324 VDVPIIGDVGHVLE---DMLRLWKARGKKPDKEAladwWGQIARWRARNSLAYTPSDDV-IMPQYAIQRLYELTKGRDTY 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 391 VTT-IGLSQIAAAQFLHVYRPRNWINCGQAGPLGWTIPAAIGAATAEPETPIVALSGDYDFQFMIEELAVAAQHKVPYVH 469
Cdd:PRK09107 400 ITTeVGQHQMWAAQFFGFEEPNRWMTSGGLGTMGYGLPAALGVQIAHPDALVIDIAGDASIQMCIQEMSTAVQYNLPVKI 479
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2429932465 470 VLVNNAYLGLIRQAQGGLGINfevnlEFENINTPELcvygVDHVKVAEGLGVKAIRVTDPDKLGEAFEE 538
Cdd:PRK09107 480 FILNNQYMGMVRQWQQLLHGN-----RLSHSYTEAM----PDFVKLAEAYGAVGIRCEKPGDLDDAIQE 539
|
|
| PRK07282 |
PRK07282 |
acetolactate synthase large subunit; |
11-558 |
2.69e-115 |
|
acetolactate synthase large subunit;
Pssm-ID: 180919 [Multi-domain] Cd Length: 566 Bit Score: 354.51 E-value: 2.69e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 11 VEILKIEGVSQAFGVPGAAINPFYRELKNVGGIGHTLARHVEGASHMAEGYTRAkAGNIGVCIGTSGPAGTDMITGLYSA 90
Cdd:PRK07282 17 LETLRDLGVDTIFGYPGGAVLPLYDAIYNFEGIRHILARHEQGALHEAEGYAKS-TGKLGVAVVTSGPGATNAITGIADA 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 91 IADSIPILCITGQAPVSKLHKEDFQAVDIASIAGPVTKKATTVLEAAQVPGVFQEAFHLMRSGRPGPVLIDLPIDVQLTE 170
Cdd:PRK07282 96 MSDSVPLLVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQIRETADIPRIITEAVHIATTGRPGPVVIDLPKDVSALE 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 171 IEFDPETYAPLPVYKP--RATRAQAAKALGFLLESQRPLIVAGGGIINADASDLLVEFAELVGVPVISTLMGWGTIPDDH 248
Cdd:PRK07282 176 TDFIYDPEVNLPSYQPtlEPNDMQIKKILKQLSKAKKPVILAGGGINYAEAATELNAFAERYQIPVVTTLLGQGTIATSH 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 249 QLAAGMVGVQTAHRyGNATFLESDFVFGIGNRWANRHTGyNLDAYTKGRTFVHVDIEPTQLGKIFAPDFGIASDAKAALE 328
Cdd:PRK07282 256 PLFLGMGGMHGSYA-ANIAMTEADFMINIGSRFDDRLTG-NPKTFAKNAKVAHIDIDPAEIGKIIKTDIPVVGDAKKALQ 333
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 329 LFIEIAKELKaegklpDFSAWAASAQERKGSLqRRTHFDDIPLKPQRVYEEMNKAFGPETRYVTTIGLSQIAAAQFLHVY 408
Cdd:PRK07282 334 MLLAEPTVHN------NTEKWIEKVTKDKNRV-RSYDKKERVVQPQAVIERIGELTNGDAIVVTDVGQHQMWAAQYYPYQ 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 409 RPRNWINCGQAGPLGWTIPAAIGAATAEPETPIVALSGDYDFQFMIEELAVAAQHKVPYVHVLVNNAYLGLIRQAQGGLG 488
Cdd:PRK07282 407 NERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVILFVGDGGFQMTNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFY 486
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 489 INFEVNLEFENINTPELcvygvdhvkVAEGLGVKAIRVTDPDKLGEAFEEAKKlaqefQVPVVVEAILER 558
Cdd:PRK07282 487 EGRTSESVFDTLPDFQL---------MAQAYGIKHYKFDNPETLAQDLEVITE-----DVPMLIEVDISR 542
|
|
| PRK07710 |
PRK07710 |
acetolactate synthase large subunit; |
3-553 |
1.71e-113 |
|
acetolactate synthase large subunit;
Pssm-ID: 236076 [Multi-domain] Cd Length: 571 Bit Score: 350.21 E-value: 1.71e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 3 RMTAAAAAVEILKIEGVSQAFGVPGAAINPFYRELKNvGGIGHTLARHVEGASHMAEGYTRAkAGNIGVCIGTSGPAGTD 82
Cdd:PRK07710 15 LMTGAQMLIEALEKEGVEVIFGYPGGAVLPLYDALYD-CGIPHILTRHEQGAIHAAEGYARI-SGKPGVVIATSGPGATN 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 83 MITGLYSAIADSIPILCITGQAPVSKLHKEDFQAVDIASIAGPVTKKATTVLEAAQVPGVFQEAFHLMRSGRPGPVLIDL 162
Cdd:PRK07710 93 VVTGLADAMIDSLPLVVFTGQVATSVIGSDAFQEADIMGITMPVTKHNYQVRKASDLPRIIKEAFHIATTGRPGPVLIDI 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 163 PIDVQLTEIEFDPETYAPLPVYKP--RATRAQAAKALGFLLESQRPLIVAGGGIINADASDLLVEFAELVGVPVISTLMG 240
Cdd:PRK07710 173 PKDMVVEEGEFCYDVQMDLPGYQPnyEPNLLQIRKLVQAVSVAKKPVILAGAGVLHAKASKELTSYAEQQEIPVVHTLLG 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 241 WGTIPDDHQLAAGMVGVQTAHRyGNATFLESDFVFGIGNRWANRHTGyNLDAYTKGRTFVHVDIEPTQLGKIFAPDFGIA 320
Cdd:PRK07710 253 LGGFPADHPLFLGMAGMHGTYT-ANMALYECDLLINIGARFDDRVTG-NLAYFAKEATVAHIDIDPAEIGKNVPTEIPIV 330
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 321 SDAKAALELFIeiakelKAEGKLPDFSAWAASAQERKGSLQRRTHFDDIPLKPQRVYEEMNKAFGPETRYVTTIGLSQIA 400
Cdd:PRK07710 331 ADAKQALQVLL------QQEGKKENHHEWLSLLKNWKEKYPLSYKRNSESIKPQKAIEMLYEITKGEAIVTTDVGQHQMW 404
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 401 AAQFLHVYRPRNWINCGQAGPLGWTIPAAIGAATAEPETPIVALSGDYDFQFMIEELAVAAQHKVPYVHVLVNNAYLGLI 480
Cdd:PRK07710 405 AAQYYPFKTPDKWVTSGGLGTMGFGLPAAIGAQLAKPDETVVAIVGDGGFQMTLQELSVIKELSLPVKVVILNNEALGMV 484
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2429932465 481 RQAQgglginfevNLEFENINTPELCVYGVDHVKVAEGLGVKAIRVTDPDklgEAFEEAKKlAQEFQVPVVVE 553
Cdd:PRK07710 485 RQWQ---------EEFYNQRYSHSLLSCQPDFVKLAEAYGIKGVRIDDEL---EAKEQLQH-AIELQEPVVID 544
|
|
| ilvB |
CHL00099 |
acetohydroxyacid synthase large subunit |
5-539 |
1.08e-111 |
|
acetohydroxyacid synthase large subunit
Pssm-ID: 214363 [Multi-domain] Cd Length: 585 Bit Score: 345.92 E-value: 1.08e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 5 TAAAAAVEILKIEGVSQAFGVPGAAINPFYREL---KNVGGIGHTLARHVEGASHMAEGYTRAkAGNIGVCIGTSGPAGT 81
Cdd:CHL00099 11 TGAFALIDSLVRHGVKHIFGYPGGAILPIYDELyawEKKGLIKHILVRHEQGAAHAADGYARS-TGKVGVCFATSGPGAT 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 82 DMITGLYSAIADSIPILCITGQAPVSKLHKEDFQAVDIASIAGPVTKKATTVLEAAQVPGVFQEAFHLMRSGRPGPVLID 161
Cdd:CHL00099 90 NLVTGIATAQMDSVPLLVITGQVGRAFIGTDAFQEVDIFGITLPIVKHSYVVRDARDISRIVAEAFYIAKHGRPGPVLID 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 162 LPIDVQLTEIE-FDPE---TYAPLPVYKP--RATRAQAAKALGFLLESQRPLIVAGGGIINADASDLLVEFAELVGVPVI 235
Cdd:CHL00099 170 IPKDVGLEKFDyYPPEpgnTIIKILGCRPiyKPTIKRIEQAAKLILQSSQPLLYVGGGAIISDAHQEITELAELYKIPVT 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 236 STLMGWGTIPDDHQLAAGMVGVQ-TAhrYGNATFLESDFVFGIGNRWANRHTGyNLDAYTKGRTFVHVDIEPTQLGKIFA 314
Cdd:CHL00099 250 TTLMGKGIFDEDHPLCLGMLGMHgTA--YANFAVSECDLLIALGARFDDRVTG-KLDEFACNAQVIHIDIDPAEIGKNRI 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 315 PDFGIASDAKAALELFIEIAKELKAEGKLPDFSAWaasaQERKgSLQRRTHFDDIP-----LKPQRVYEEMNKaFGPETR 389
Cdd:CHL00099 327 PQVAIVGDVKKVLQELLELLKNSPNLLESEQTQAW----RERI-NRWRKEYPLLIPkpstsLSPQEVINEISQ-LAPDAY 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 390 YVTTIGLSQIAAAQFLHVYrPRNWINCGQAGPLGWTIPAAIGAATAEPETPIVALSGDYDFQFMIEELAVAAQHKVPYVH 469
Cdd:CHL00099 401 FTTDVGQHQMWAAQFLKCK-PRKWLSSAGLGTMGYGLPAAIGAQIAHPNELVICISGDASFQMNLQELGTIAQYNLPIKI 479
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2429932465 470 VLVNNAYLGLIRQAQGGLginFEVNLEFENIN--TPelcvygvDHVKVAEGLGVKAIRVTDPDKLGEAFEEA 539
Cdd:CHL00099 480 IIINNKWQGMVRQWQQAF---YGERYSHSNMEegAP-------DFVKLAEAYGIKGLRIKSRKDLKSSLKEA 541
|
|
| PRK08155 |
PRK08155 |
acetolactate synthase large subunit; |
1-524 |
5.38e-111 |
|
acetolactate synthase large subunit;
Pssm-ID: 181257 [Multi-domain] Cd Length: 564 Bit Score: 343.61 E-value: 5.38e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 1 MPRMTAAAAAVEILKIEGVSQAFGVPGAAINPFYRELKNVGGIGHTLARHVEGASHMAEGYTRAKaGNIGVCIGTSGPAG 80
Cdd:PRK08155 10 RKRFTGAELIVRLLERQGIRIVTGIPGGAILPLYDALSQSTQIRHILARHEQGAGFIAQGMARTT-GKPAVCMACSGPGA 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 81 TDMITGLYSAIADSIPILCITGQAPVSKLHKEDFQAVDIASIAGPVTKKATTVLEAAQVPGVFQEAFHLMRSGRPGPVLI 160
Cdd:PRK08155 89 TNLVTAIADARLDSIPLVCITGQVPASMIGTDAFQEVDTYGISIPITKHNYLVRDIEELPQVISDAFRIAQSGRPGPVWI 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 161 DLPIDVQLTEIEFD----PETYAPLPVYKPRATRAQAAkalgFLLESQRPLIVAGGGIINADASDLLVEFAELVGVPVIS 236
Cdd:PRK08155 169 DIPKDVQTAVIELEalpaPAEKDAAPAFDEESIRDAAA----MINAAKRPVLYLGGGVINSGAPARARELAEKAQLPTTM 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 237 TLMGWGTIPDDHQLAAGMVGVQTAhRYGNATFLESDFVFGIGNRWANRHTGyNLDAYTKGRTFVHVDIEPTQLGKIFAPD 316
Cdd:PRK08155 245 TLMALGMLPKAHPLSLGMLGMHGA-RSTNYILQEADLLIVLGARFDDRAIG-KTEQFCPNAKIIHVDIDRAELGKIKQPH 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 317 FGIASDAKAALELFI-EIAKELKAEgklpdfsaWaasaQERKGSLQRRTHFD----DIPLKPQRVYEEMNKAFGPETRYV 391
Cdd:PRK08155 323 VAIQADVDDVLAQLLpLVEAQPRAE--------W----HQLVADLQREFPCPipkaDDPLSHYGLINAVAACVDDNAIIT 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 392 TTIGLSQIAAAQFLHVYRPRNWINCGQAGPLGWTIPAAIGAATAEPETPIVALSGDYDFQFMIEELAVAAQHKVPYVHVL 471
Cdd:PRK08155 391 TDVGQHQMWTAQAYPLNRPRQWLTSGGLGTMGFGLPAAIGAALANPERKVLCFSGDGSLMMNIQEMATAAENQLDVKIIL 470
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|...
gi 2429932465 472 VNNAYLGLIRQAQgglginfevNLEFENINTPELCVYGVDHVKVAEGLGVKAI 524
Cdd:PRK08155 471 MNNEALGLVHQQQ---------SLFYGQRVFAATYPGKINFMQIAAGFGLETC 514
|
|
| PRK06882 |
PRK06882 |
acetolactate synthase 3 large subunit; |
1-548 |
7.39e-106 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 168717 [Multi-domain] Cd Length: 574 Bit Score: 330.34 E-value: 7.39e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 1 MPRMTAAAAAVEILKIEGVSQAFGVPGAAINPFYRELKNVGGIGHTLARHVEGASHMAEGYTRAkAGNIGVCIGTSGPAG 80
Cdd:PRK06882 1 MKKLSGAEMVVQSLRDEGVEYVFGYPGGSVLDIYDAIHTLGGIEHVLVRHEQAAVHMADGYARS-TGKVGCVLVTSGPGA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 81 TDMITGLYSAIADSIPILCITGQAPVSKLHKEDFQAVDIASIAGPVTKKATTVLEAAQVPGVFQEAFHLMRSGRPGPVLI 160
Cdd:PRK06882 80 TNAITGIATAYTDSVPLVILSGQVPSNLIGTDAFQECDMLGISRPVVKHSFIVKNAEDIPSTIKKAFYIASTGRPGPVVI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 161 DLPIDVQLTEIEFDPE--TYAPLPVYKP--RATRAQAAKALGFLLESQRPLIVAGGGIINADASDLLVEFAELVGVPVIS 236
Cdd:PRK06882 160 DIPKDMVNPANKFTYEypEEVSLRSYNPtvQGHKGQIKKALKALLVAKKPVLFVGGGVITAECSEQLTQFAQKLNLPVTS 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 237 TLMGWGTIPDDHQLAAGMVGVQTAHRYGNATFlESDFVFGIGNRWANRHTGyNLDAYTKGRTFVHVDIEPTQLGKIFAPD 316
Cdd:PRK06882 240 SLMGLGAYPSTDKQFLGMLGMHGTYEANNAMH-ESDLILGIGVRFDDRTTN-NLAKYCPNAKVIHIDIDPTSISKNVPAY 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 317 FGIASDAKAALELFIEIAKELKAEGKLPDFSAWAASAQERKGSLQRRTHFDDIPLKPQRVYEEMNKAFGPETRYVTTIGL 396
Cdd:PRK06882 318 IPIVGSAKNVLEEFLSLLEEENLAKSQTDLTAWWQQINEWKAKKCLEFDRTSDVIKPQQVVEAIYRLTNGDAYVASDVGQ 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 397 SQIAAAQFLHVYRPRNWINCGQAGPLGWTIPAAIGAATAEPETPIVALSGDYDFQFMIEELAVAAQHKVPYVHVLVNNAY 476
Cdd:PRK06882 398 HQMFAALHYPFDKPRRWINSGGAGTMGFGLPAAIGVKFAHPEATVVCVTGDGSIQMNIQELSTAKQYDIPVVIVSLNNRF 477
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2429932465 477 LGLIRQAQgglginfevNLEFENINTPELCVYGVDHVKVAEGLGVKAIRVTDPDKLGEafeeakKLAQEFQV 548
Cdd:PRK06882 478 LGMVKQWQ---------DLIYSGRHSQVYMNSLPDFAKLAEAYGHVGIQIDTPDELEE------KLTQAFSI 534
|
|
| PRK07979 |
PRK07979 |
acetolactate synthase 3 large subunit; |
1-541 |
3.60e-105 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 181185 [Multi-domain] Cd Length: 574 Bit Score: 328.73 E-value: 3.60e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 1 MPRMTAAAAAVEILKIEGVSQAFGVPGAAINPFYRELKNVGGIGHTLARHVEGASHMAEGYTRAkAGNIGVCIGTSGPAG 80
Cdd:PRK07979 1 MEMLSGAEMVVRSLIDQGVKQVFGYPGGAVLDIYDALHTVGGIDHVLVRHEQAAVHMADGLARA-TGEVGVVLVTSGPGA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 81 TDMITGLYSAIADSIPILCITGQAPVSKLHKEDFQAVDIASIAGPVTKKATTVLEAAQVPGVFQEAFHLMRSGRPGPVLI 160
Cdd:PRK07979 80 TNAITGIATAYMDSIPLVVLSGQVATSLIGYDAFQECDMVGISRPVVKHSFLVKQTEDIPQVLKKAFWLAASGRPGPVVV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 161 DLPIDVQLTEIEFD---PETYApLPVYKPRAT--RAQAAKALGFLLESQRPLIVAGGGIINADASDLLVEFAELVGVPVI 235
Cdd:PRK07979 160 DLPKDILNPANKLPyvwPESVS-MRSYNPTTQghKGQIKRALQTLVAAKKPVVYVGGGAINAACHQQLKELVEKLNLPVV 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 236 STLMGWGTIPDDHQLAAGMVGVQTAHRyGNATFLESDFVFGIGNRWANRHTGyNLDAYTKGRTFVHVDIEPTQLGKIFAP 315
Cdd:PRK07979 239 SSLMGLGAFPATHRQSLGMLGMHGTYE-ANMTMHNADVIFAVGVRFDDRTTN-NLAKYCPNATVLHIDIDPTSISKTVTA 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 316 DFGIASDAKAALELFIEIAKELKAEGKLPDFSAWAASAQERKGSLQRRTHFDDIPLKPQRVYEEMNKAFGPETRYVTTIG 395
Cdd:PRK07979 317 DIPIVGDARQVLEQMLELLSQESAHQPLDEIRDWWQQIEQWRARQCLKYDTHSEKIKPQAVIETLWRLTKGDAYVTSDVG 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 396 LSQIAAAQFLHVYRPRNWINCGQAGPLGWTIPAAIGAATAEPETPIVALSGDYDFQFMIEELAVAAQHKVPYVHVLVNNA 475
Cdd:PRK07979 397 QHQMFAALYYPFDKPRRWINSGGLGTMGFGLPAALGVKMALPEETVVCVTGDGSIQMNIQELSTALQYELPVLVLNLNNR 476
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 476 YLGLIRQAQGGLGINFEVNLEFENINtpelcvygvDHVKVAEGLGVKAIRVTDPD----KLGEAFEEAKK 541
Cdd:PRK07979 477 YLGMVKQWQDMIYSGRHSQSYMQSLP---------DFVRLAEAYGHVGIQISHPDelesKLSEALEQVRN 537
|
|
| PRK08979 |
PRK08979 |
acetolactate synthase 3 large subunit; |
1-539 |
4.50e-104 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 181602 [Multi-domain] Cd Length: 572 Bit Score: 325.62 E-value: 4.50e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 1 MPRMTAAAAAVEILKIEGVSQAFGVPGAAINPFYRELKNVGGIGHTLARHVEGASHMAEGYTRAkAGNIGVCIGTSGPAG 80
Cdd:PRK08979 1 MEMLSGASMIVRSLIDEGVKHIFGYPGGSVLDIYDALHEKSGIEHILVRHEQAAVHMADGYARA-TGKVGVVLVTSGPGA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 81 TDMITGLYSAIADSIPILCITGQAPVSKLHKEDFQAVDIASIAGPVTKKATTVLEAAQVPGVFQEAFHLMRSGRPGPVLI 160
Cdd:PRK08979 80 TNTITGIATAYMDSIPMVVLSGQVPSNLIGNDAFQECDMIGISRPVVKHSFLVKDAEDIPEIIKKAFYIASTGRPGPVVI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 161 DLPIDVQLTEIEFD---PETYApLPVYKPRAT--RAQAAKALGFLLESQRPLIVAGGGIINADASDLLVEFAELVGVPVI 235
Cdd:PRK08979 160 DLPKDCLNPAILHPyeyPESIK-MRSYNPTTSghKGQIKRGLQALLAAKKPVLYVGGGAIISGADKQILQLAEKLNLPVV 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 236 STLMGWGTIPDDHQLAAGMVGVQTAHRyGNATFLESDFVFGIGNRWANRHTGyNLDAYTKGRTFVHVDIEPTQLGKIFAP 315
Cdd:PRK08979 239 STLMGLGAFPGTHKNSLGMLGMHGRYE-ANMAMHNADLIFGIGVRFDDRTTN-NLEKYCPNATILHIDIDPSSISKTVRV 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 316 DFGIASDAKAALELFIEIAKELKAEGKLPDFSAW---AASAQERKgSLQRRTHFDDIplKPQRVYEEMNKAFGPETRYVT 392
Cdd:PRK08979 317 DIPIVGSADKVLDSMLALLDESGETNDEAAIASWwneIEVWRSRN-CLAYDKSSERI--KPQQVIETLYKLTNGDAYVAS 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 393 TIGLSQIAAAQFLHVYRPRNWINCGQAGPLGWTIPAAIGAATAEPETPIVALSGDYDFQFMIEELAVAAQHKVPYVHVLV 472
Cdd:PRK08979 394 DVGQHQMFAALYYPFDKPRRWINSGGLGTMGFGLPAAMGVKFAMPDETVVCVTGDGSIQMNIQELSTALQYDIPVKIINL 473
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2429932465 473 NNAYLGLIRQAQGGLGINFEVNLEFENIntPelcvygvDHVKVAEGLGVKAIRVTDPDKLGEAFEEA 539
Cdd:PRK08979 474 NNRFLGMVKQWQDMIYQGRHSHSYMDSV--P-------DFAKIAEAYGHVGIRISDPDELESGLEKA 531
|
|
| PRK08978 |
PRK08978 |
acetolactate synthase 2 catalytic subunit; Reviewed |
4-484 |
2.57e-101 |
|
acetolactate synthase 2 catalytic subunit; Reviewed
Pssm-ID: 181601 [Multi-domain] Cd Length: 548 Bit Score: 317.98 E-value: 2.57e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 4 MTAAAAAVEILKIEGVSQAFGVPGAAINPFYRELKNvGGIGHTLARHVEGASHMAEGYTRAkAGNIGVCIGTSGPAGTDM 83
Cdd:PRK08978 1 MNGAQWVVHALRAQGVDTVFGYPGGAIMPVYDALYD-GGVEHLLCRHEQGAAMAAIGYARA-TGKVGVCIATSGPGATNL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 84 ITGLYSAIADSIPILCITGQAPVSKLHKEDFQAVDIASIAGPVTKKATTVLEAAQVPGVFQEAFHLMRSGRPGPVLIDLP 163
Cdd:PRK08978 79 ITGLADALLDSVPVVAITGQVSSPLIGTDAFQEIDVLGLSLACTKHSFLVQSLEELPEIMAEAFEIASSGRPGPVLVDIP 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 164 IDVQLTEIEFDPETYAPLPvyKPRATRAQAAKALGFLLESQRPLIVAGGGIINADASDLLVEFAELVGVPVISTLMGWGT 243
Cdd:PRK08978 159 KDIQLAEGELEPHLTTVEN--EPAFPAAELEQARALLAQAKKPVLYVGGGVGMAGAVPALREFLAATGMPAVATLKGLGA 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 244 IPDDHQLAAGMVGVqtaH--RYGNATFLESDFVFGIGNRWANRHTGyNLDAYTKGRTFVHVDIEPTQLGKIFAPDFGIAS 321
Cdd:PRK08978 237 VEADHPYYLGMLGM---HgtKAANLAVQECDLLIAVGARFDDRVTG-KLNTFAPHAKVIHLDIDPAEINKLRQAHVALQG 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 322 DAKAALElfiEIAKELkaegklpDFSAWaasaqeRKGSLQRRTHF--------DDI--PLKPQRVYEEMnkafgPETRYV 391
Cdd:PRK08978 313 DLNALLP---ALQQPL-------NIDAW------RQHCAQLRAEHawrydhpgEAIyaPALLKQLSDRK-----PADTVV 371
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 392 TT-IGLSQIAAAQFLHVYRPRNWINCGQAGPLGWTIPAAIGAATAEPETPIVALSGDYDFQFMIEELAVAAQHKVPYVHV 470
Cdd:PRK08978 372 TTdVGQHQMWVAQHMRFTRPENFITSSGLGTMGFGLPAAIGAQVARPDDTVICVSGDGSFMMNVQELGTIKRKQLPVKIV 451
|
490
....*....|....
gi 2429932465 471 LVNNAYLGLIRQAQ 484
Cdd:PRK08978 452 LLDNQRLGMVRQWQ 465
|
|
| PLN02470 |
PLN02470 |
acetolactate synthase |
11-538 |
3.56e-100 |
|
acetolactate synthase
Pssm-ID: 215261 [Multi-domain] Cd Length: 585 Bit Score: 315.91 E-value: 3.56e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 11 VEILKIEGVSQAFGVPGAAINPFYRELKNVGGIGHTLARHVEGASHMAEGYTRAkAGNIGVCIGTSGPAGTDMITGLYSA 90
Cdd:PLN02470 20 VEALEREGVDTVFAYPGGASMEIHQALTRSNCIRNVLCRHEQGEVFAAEGYAKA-SGKVGVCIATSGPGATNLVTGLADA 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 91 IADSIPILCITGQAPVSKLHKEDFQAVDIASIAGPVTKKATTVLEAAQVPGVFQEAFHLMRSGRPGPVLIDLPIDVQLTE 170
Cdd:PLN02470 99 LLDSVPLVAITGQVPRRMIGTDAFQETPIVEVTRSITKHNYLVMDVEDIPRVIREAFFLASSGRPGPVLVDIPKDIQQQL 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 171 IEFDPETYAPLPVYKPR----ATRAQAAKALGFLLESQRPLIVAGGGIINadASDLLVEFAELVGVPVISTLMGWGTIPD 246
Cdd:PLN02470 179 AVPNWNQPMKLPGYLSRlpkpPEKSQLEQIVRLISESKRPVVYVGGGCLN--SSEELREFVELTGIPVASTLMGLGAFPA 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 247 DHQLAAGMVGVQTAhRYGNATFLESDFVFGIGNRWANRHTGyNLDAYTKGRTFVHVDIEPTQLGKIFAPDFGIASDAKAA 326
Cdd:PLN02470 257 SDELSLQMLGMHGT-VYANYAVDSADLLLAFGVRFDDRVTG-KLEAFASRASIVHIDIDPAEIGKNKQPHVSVCADVKLA 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 327 LELFIEIAKELKAegKLPDFSAWAA--SAQERKGSLQRRTHFDDIPlkPQRVYEEMNKAFGPETRYVTTIGLSQIAAAQF 404
Cdd:PLN02470 335 LQGLNKLLEERKA--KRPDFSAWRAelDEQKEKFPLSYPTFGDAIP--PQYAIQVLDELTDGNAIISTGVGQHQMWAAQW 410
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 405 LHVYRPRNWINCGQAGPLGWTIPAAIGAATAEPETPIVALSGDYDFQFMIEELAVAAQHKVPYVHVLVNNAYLGLIRQAQ 484
Cdd:PLN02470 411 YKYKEPRRWLTSGGLGAMGFGLPAAIGAAAANPDAIVVDIDGDGSFIMNIQELATIHVENLPVKIMVLNNQHLGMVVQWE 490
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*.
gi 2429932465 485 GGLginFEVNLEFENINTP--ELCVYGvDHVKVAEGLGVKAIRVTDPDKLGEAFEE 538
Cdd:PLN02470 491 DRF---YKANRAHTYLGDPdaEAEIFP-DFLKFAEGCKIPAARVTRKSDLREAIQK 542
|
|
| PRK06466 |
PRK06466 |
acetolactate synthase 3 large subunit; |
1-539 |
2.16e-98 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 180578 [Multi-domain] Cd Length: 574 Bit Score: 310.91 E-value: 2.16e-98
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 1 MPRMTAAAAAVEILKIEGVSQAFGVPGAAINPFYRELKNVGGIGHTLARHVEGASHMAEGYTRAkAGNIGVCIGTSGPAG 80
Cdd:PRK06466 1 MELLSGAEMLVRALRDEGVEYIYGYPGGAVLHIYDALFKQDKVEHILVRHEQAATHMADGYARA-TGKTGVVLVTSGPGA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 81 TDMITGLYSAIADSIPILCITGQAPVSKLHKEDFQAVDIASIAGPVTKKATTVLEAAQVPGVFQEAFHLMRSGRPGPVLI 160
Cdd:PRK06466 80 TNAITGIATAYMDSIPMVVLSGQVPSTLIGEDAFQETDMVGISRPIVKHSFMVKHASEIPEIIKKAFYIAQSGRPGPVVV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 161 DLPIDVQLTEIEFD---PETyAPLPVYKP--RATRAQAAKALGFLLESQRPLIVAGGGIINADASDLLVEFAELVGVPVI 235
Cdd:PRK06466 160 DIPKDMTNPAEKFEyeyPKK-VKLRSYSPavRGHSGQIRKAVEMLLAAKRPVIYSGGGVVLGNASALLTELAHLLNLPVT 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 236 STLMGWGTIPDDHQLAAGMVGVQTAHRyGNATFLESDFVFGIGNRWANRHTGyNLDAYTKGRTFVHVDIEPTQLGKIFAP 315
Cdd:PRK06466 239 NTLMGLGGFPGTDRQFLGMLGMHGTYE-ANMAMHHADVILAVGARFDDRVTN-GPAKFCPNAKIIHIDIDPASISKTIKA 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 316 DFGIASDAKAALELFIEIAKELKAEGKLPDFSAWAASAQE-RK-GSLQRRTHFDDIPLKPQRVYEEMNKAFGPETrYVTT 393
Cdd:PRK06466 317 DIPIVGPVESVLTEMLAILKEIGEKPDKEALAAWWKQIDEwRGrHGLFPYDKGDGGIIKPQQVVETLYEVTNGDA-YVTS 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 394 -IGLSQIAAAQFLHVYRPRNWINCGQAGPLGWTIPAAIGAATAEPETPIVALSGDYDFQFMIEELAVAAQHKVPYVHVLV 472
Cdd:PRK06466 396 dVGQHQMFAAQYYKFNKPNRWINSGGLGTMGFGLPAAMGVKLAFPDQDVACVTGEGSIQMNIQELSTCLQYGLPVKIINL 475
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2429932465 473 NNAYLGLIRQAQgglginfevNLEFENINTPELCVYGVDHVKVAEGLGVKAIRVTDPDKLGEAFEEA 539
Cdd:PRK06466 476 NNGALGMVRQWQ---------DMQYEGRHSHSYMESLPDFVKLAEAYGHVGIRITDLKDLKPKLEEA 533
|
|
| PRK06965 |
PRK06965 |
acetolactate synthase 3 catalytic subunit; Validated |
2-542 |
1.35e-93 |
|
acetolactate synthase 3 catalytic subunit; Validated
Pssm-ID: 180780 [Multi-domain] Cd Length: 587 Bit Score: 299.03 E-value: 1.35e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 2 PRMTAAAAAVEILKIEGVSQAFGVPGAAINPFYRELKNVGGIGHTLARHVEGASHMAEGYTRAkAGNIGVCIGTSGPAGT 81
Cdd:PRK06965 19 ADSIGAEILMKALAAEGVEFIWGYPGGAVLYIYDELYKQDKIQHVLVRHEQAAVHAADGYARA-TGKVGVALVTSGPGVT 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 82 DMITGLYSAIADSIPILCITGQAPVSKLHKEDFQAVDIASIAGPVTKKATTVLEAAQVPGVFQEAFHLMRSGRPGPVLID 161
Cdd:PRK06965 98 NAVTGIATAYMDSIPMVVISGQVPTAAIGQDAFQECDTVGITRPIVKHNFLVKDVRDLAETVKKAFYIARTGRPGPVVVD 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 162 LPIDVQLTEIEFDPETYAPLPVYKP--RATRAQAAKALGFLLESQRPLIVAGGGIINADASDLLVEFAELVGVPVISTLM 239
Cdd:PRK06965 178 IPKDVSKTPCEYEYPKSVEMRSYNPvtKGHSGQIRKAVSLLLSAKRPYIYTGGGVILANASRELRQLADLLGYPVTNTLM 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 240 GWGTIPDDHQLAAGMVGVQTAHRYGNAtFLESDFVFGIGNRWANRHTGYNLDAYTKGRTFVHVDIEPTQLGKIFAPDFGI 319
Cdd:PRK06965 258 GLGAYPASDKKFLGMLGMHGTYEANMA-MQHCDVLIAIGARFDDRVIGNPAHFASRPRKIIHIDIDPSSISKRVKVDIPI 336
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 320 ASDAKAALELFIEIAKELKAEgklPDFSA----WAASAQERKGSLQRRTHFDDIpLKPQRVYEEMNKAFGPETRYVTTIG 395
Cdd:PRK06965 337 VGDVKEVLKELIEQLQTAEHG---PDADAlaqwWKQIEGWRSRDCLKYDRESEI-IKPQYVVEKLWELTDGDAFVCSDVG 412
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 396 LSQIAAAQFLHVYRPRNWINCGQAGPLGWTIPAAIGAATAEPETPIVALSGDYDFQFMIEELAVAAQHKVPYVHVLVNNA 475
Cdd:PRK06965 413 QHQMWAAQFYRFNEPRRWINSGGLGTMGVGLPYAMGIKMAHPDDDVVCITGEGSIQMCIQELSTCLQYDTPVKIISLNNR 492
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2429932465 476 YLGLIRQAQgglginfevNLEFENINTPELCVYGVDHVKVAEGLGVKAIRVTDPDKLGEAFEEAKKL 542
Cdd:PRK06965 493 YLGMVRQWQ---------EIEYSKRYSHSYMDALPDFVKLAEAYGHVGMRIEKTSDVEPALREALRL 550
|
|
| PRK06456 |
PRK06456 |
acetolactate synthase large subunit; |
1-555 |
7.97e-91 |
|
acetolactate synthase large subunit;
Pssm-ID: 180569 [Multi-domain] Cd Length: 572 Bit Score: 291.36 E-value: 7.97e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 1 MPrmTAAAAAVEILKIEGVSQAFGVPGAAINPFY----RELKNvGGIGHTLARHVEGASHMAEGYTRAkAGNIGVCIGTS 76
Cdd:PRK06456 1 MP--TGARILVDSLKREGVKVIFGIPGLSNMQIYdafvEDLAN-GELRHVLMRHEQAAAHAADGYARA-SGVPGVCTATS 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 77 GPAGTDMITGLYSAIADSIPILCITGQAPVSKLHKEDFQAVDIASIAGPVTKKATTVLEAAQVPGVFQEAFHLMRSGRPG 156
Cdd:PRK06456 77 GPGTTNLVTGLITAYWDSSPVIAITGQVPRSVMGKMAFQEADAMGVFENVTKYVIGIKRIDEIPQWIKNAFYIATTGRPG 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 157 PVLIDLPIDVQLTEIEFDPETYAPL-PVYKP---RATRAQAAKALGFLLESQRPLIVAGGGIINADASDLLVEFAELVGV 232
Cdd:PRK06456 157 PVVIDIPRDIFYEKMEEIKWPEKPLvKGYRDfptRIDRLALKKAAEILINAERPIILVGTGVVWSNATPEVLELAELLHI 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 233 PVISTLMGWGTIPDDHQLAAGMVGVqtahrYGNA----TFLESDFVFGIGNRWANRH-TGYNLDAYTKgRTFVHVDIEPT 307
Cdd:PRK06456 237 PIVSTFPGKTAIPHDHPLYFGPMGY-----YGRAeasmAALESDAMLVVGARFSDRTfTSYDEMVETR-KKFIMVNIDPT 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 308 QLGKIFAPDFGIASDAKAALElfiEIAKELKAEGKLPDFSAWAASAQERKGSL-QRRTHFDDIPLKPQRVYEEMNKAFgP 386
Cdd:PRK06456 311 DGEKAIKVDVGIYGNAKIILR---ELIKAITELGQKRDRSAWLKRVKEYKEYYsQFYYTEENGKLKPWKIMKTIRQAL-P 386
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 387 ETRYVTT-IGLSQIAAAQFLHVYRPRNWINCGQAGPLGWTIPAAIGAATAEPETPIVALSGDYDFQFMIEELAVAAQHKV 465
Cdd:PRK06456 387 RDAIVTTgVGQHQMWAEVFWEVLEPRTFLTSSGMGTMGFGLPAAMGAKLARPDKVVVDLDGDGSFLMTGTNLATAVDEHI 466
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 466 PYVHVLVNNAYLGLIRQAQGGLGINFEVNLEFENintpelcvyGVDHVKVAEGLGVKAIRVTDPDKLGEAFEEAKK--LA 543
Cdd:PRK06456 467 PVISVIFDNRTLGLVRQVQDLFFGKRIVGVDYGP---------SPDFVKLAEAFGALGFNVTTYEDIEKSLKSAIKedIP 537
|
570
....*....|..
gi 2429932465 544 QEFQVPVVVEAI 555
Cdd:PRK06456 538 AVIRVPVDKEEL 549
|
|
| PRK08266 |
PRK08266 |
hypothetical protein; Provisional |
1-558 |
1.31e-84 |
|
hypothetical protein; Provisional
Pssm-ID: 181337 [Multi-domain] Cd Length: 542 Bit Score: 274.20 E-value: 1.31e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 1 MPRMTAAAAAVEILKIEGVSQAFGVPGA----AINPFYRELKNVGGIGhtlARHVEGASHMAEGYTRAkAGNIGVCIGTS 76
Cdd:PRK08266 1 MTTMTGGEAIVAGLVAHGVDTVFGLPGAqlywLFDALYKAGDRIRVIH---TRHEQAAGYMAFGYARS-TGRPGVCSVVP 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 77 GPAGTDMITGLYSAIADSIPILCITGQAPVS-------KLHkedfQAVDIASIAGPVTKKATTVLEAAQVPGVFQEAFHL 149
Cdd:PRK08266 77 GPGVLNAGAALLTAYGCNSPVLCLTGQIPSAligkgrgHLH----EMPDQLATLRSFTKWAERIEHPSEAPALVAEAFQQ 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 150 MRSGRPGPVLIDLPIDV-QLTEIEFDPETYAPLPVYKPRATRAQAAKALgfLLESQRPLIVAGGGIinADASDLLVEFAE 228
Cdd:PRK08266 153 MLSGRPRPVALEMPWDVfGQRAPVAAAPPLRPAPPPAPDPDAIAAAAAL--IAAAKNPMIFVGGGA--AGAGEEIRELAE 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 229 LVGVPVISTLMGWGTIPDDHQLAAGMVGvqtahryGNATFLESDFVFGIGNR-------WANRhtgynldayTKGRTFVH 301
Cdd:PRK08266 229 MLQAPVVAFRSGRGIVSDRHPLGLNFAA-------AYELWPQTDVVIGIGSRlelptfrWPWR---------PDGLKVIR 292
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 302 VDIEPTQLGKiFAPDFGIASDAKAALELFIEIAKEL--KAEGKLPDFSAWAASAQERKGSLQrrthfddiplkPQRVYEE 379
Cdd:PRK08266 293 IDIDPTEMRR-LKPDVAIVADAKAGTAALLDALSKAgsKRPSRRAELRELKAAARQRIQAVQ-----------PQASYLR 360
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 380 MNKAFGPETRYVTTiGLSQIAAAQFLH--VYRPRNWINCGQAGPLGWTIPAAIGAATAEPETPIVALSGDYDFQFMIEEL 457
Cdd:PRK08266 361 AIREALPDDGIFVD-ELSQVGFASWFAfpVYAPRTFVTCGYQGTLGYGFPTALGAKVANPDRPVVSITGDGGFMFGVQEL 439
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 458 AVAAQHKVPYVHVLVNNAYLGLIRQAQGGLGINFEVNLEFENintPelcvygvDHVKVAEGLGVKAIRVTDPDKLGEAFE 537
Cdd:PRK08266 440 ATAVQHNIGVVTVVFNNNAYGNVRRDQKRRFGGRVVASDLVN---P-------DFVKLAESFGVAAFRVDSPEELRAALE 509
|
570 580
....*....|....*....|.
gi 2429932465 538 EAKKLAQefqvPVVVEAILER 558
Cdd:PRK08266 510 AALAHGG----PVLIEVPVPR 526
|
|
| PRK08322 |
PRK08322 |
acetolactate synthase large subunit; |
4-553 |
1.70e-77 |
|
acetolactate synthase large subunit;
Pssm-ID: 236239 [Multi-domain] Cd Length: 547 Bit Score: 255.52 E-value: 1.70e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 4 MTAAAAAVEILKIEGVSQAFGVPGAAINPFYRELKNvGGIGHTLARHVEGASHMAEGYTRAkAGNIGVCIGTSGPAGTDM 83
Cdd:PRK08322 1 MKAADLFVKCLENEGVEYIFGIPGEENLDLLEALRD-SSIKLILTRHEQGAAFMAATYGRL-TGKAGVCLSTLGPGATNL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 84 ITGLYSAIADSIPILCITGQAPVSKLHKEDFQAVDIASIAGPVTKKATTVLEAAQVPGVFQEAFHLMRSGRPGPVLIDLP 163
Cdd:PRK08322 79 VTGVAYAQLGGMPMVAITGQKPIKRSKQGSFQIVDVVAMMAPLTKWTRQIVSPDNIPEVVREAFRLAEEERPGAVHLELP 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 164 IDVqlTEIEFDPETYAPLPVYKPRATRAQAAKALGFLLESQRPLIVAGGGIINADASDLLVEFAELVGVPVISTLMGWGT 243
Cdd:PRK08322 159 EDI--AAEETDGKPLPRSYSRRPYASPKAIERAAEAIQAAKNPLILIGAGANRKTASKALTEFVDKTGIPFFTTQMGKGV 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 244 IPDDHQLAAGMVGVQtAHRYGNATFLESDFVFGIGN--------RWaNRHTgynldaytkGRTFVHVDIEPTQLGKIFAP 315
Cdd:PRK08322 237 IPETHPLSLGTAGLS-QGDYVHCAIEHADLIINVGHdviekppfFM-NPNG---------DKKVIHINFLPAEVDPVYFP 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 316 DFGIASDAKAALElfiEIAKELkAEGKLPDFSAWAASAQERKGSLQRRTHFDDIPLKPQRVYEEMNKAFGPETRYVTTIG 395
Cdd:PRK08322 306 QVEVVGDIANSLW---QLKERL-ADQPHWDFPRFLKIREAIEAHLEEGADDDRFPMKPQRIVADLRKVMPDDDIVILDNG 381
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 396 LSQIAAAQFLHVYRPrN--WINCGQAGpLGWTIPAAIGAATAEPETPIVALSGDYDFQFMIEELAVAAQHKVPYVHVLVN 473
Cdd:PRK08322 382 AYKIWFARNYRAYEP-NtcLLDNALAT-MGAGLPSAIAAKLVHPDRKVLAVCGDGGFMMNSQELETAVRLGLPLVVLILN 459
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 474 -NAYlGLIRQAQGGLGinFEV-NLEFENintPelcvygvDHVKVAEGLGVKAIRVTDPDKLGEAFEEAkkLAQEfqVPVV 551
Cdd:PRK08322 460 dNAY-GMIRWKQENMG--FEDfGLDFGN---P-------DFVKYAESYGAKGYRVESADDLLPTLEEA--LAQP--GVHV 522
|
..
gi 2429932465 552 VE 553
Cdd:PRK08322 523 ID 524
|
|
| PRK07524 |
PRK07524 |
5-guanidino-2-oxopentanoate decarboxylase; |
5-553 |
6.20e-75 |
|
5-guanidino-2-oxopentanoate decarboxylase;
Pssm-ID: 236041 [Multi-domain] Cd Length: 535 Bit Score: 248.35 E-value: 6.20e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 5 TAAAAAVEILKIEGVSQAFGVPGAAINPFYRELKNvGGIGHTLARHVEGASHMAEGYTRAkAGNIGVCIGTSGPAGTDMI 84
Cdd:PRK07524 3 TCGEALVRLLEAYGVETVFGIPGVHTVELYRGLAG-SGIRHVTPRHEQGAGFMADGYARV-SGKPGVCFIITGPGMTNIA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 85 TGLYSAIADSIPILCITGQAPVS-------KLHK-EDFQAVdiasiAGPVTKKATTVLEAAQVPGVFQEAFHLMRSGRPG 156
Cdd:PRK07524 81 TAMGQAYADSIPMLVISSVNRRAslgkgrgKLHElPDQRAM-----VAGVAAFSHTLMSAEDLPEVLARAFAVFDSARPR 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 157 PVLIDLPIDVQLTEIEFDPeTYAPLPVYKPRATRAQAAKALGFLLESQRPLIVAGGGIInaDASDLLVEFAELVGVPVIS 236
Cdd:PRK07524 156 PVHIEIPLDVLAAPADHLL-PAPPTRPARPGPAPAALAQAAERLAAARRPLILAGGGAL--AAAAALRALAERLDAPVAL 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 237 TLMGWGTIPDDHQLAAGMVGVQTAHRygnATFLESDFVFGIGNRWANrhTGYnlDAYTKGR-----TFVHVDIEPTQLGK 311
Cdd:PRK07524 233 TINAKGLLPAGHPLLLGASQSLPAVR---ALIAEADVVLAVGTELGE--TDY--DVYFDGGfplpgELIRIDIDPDQLAR 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 312 IFAPDFGIASDAKAALELFIEiakelkaegKLPDFSAWAASAQERKGSLQrrthfddiplkpQRVYEEMNKAFGPETRYV 391
Cdd:PRK07524 306 NYPPALALVGDARAALEALLA---------RLPGQAAAADWGAARVAALR------------QALRAEWDPLTAAQVALL 364
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 392 TTIgLSQIAAAQFLH-----VY---------RPRNWINCGQA-GPLGWTIPAAIGAATAEPETPIVALSGDYDFQFMIEE 456
Cdd:PRK07524 365 DTI-LAALPDAIFVGdstqpVYagnlyfdadAPRRWFNASTGyGTLGYGLPAAIGAALGAPERPVVCLVGDGGLQFTLPE 443
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 457 LAVAAQHKVPYVHVLVNNAYLGLIRQAQGGLGInfevnlefeninTPELC-VYGVDHVKVAEGLGVKAIRVTDPDKLGEA 535
Cdd:PRK07524 444 LASAVEADLPLIVLLWNNDGYGEIRRYMVARDI------------EPVGVdPYTPDFIALARAFGCAAERVADLEQLQAA 511
|
570
....*....|....*...
gi 2429932465 536 FEEAKKLAQefqvPVVVE 553
Cdd:PRK07524 512 LRAAFARPG----PTLIE 525
|
|
| PRK08611 |
PRK08611 |
pyruvate oxidase; Provisional |
1-555 |
2.34e-72 |
|
pyruvate oxidase; Provisional
Pssm-ID: 181502 [Multi-domain] Cd Length: 576 Bit Score: 242.60 E-value: 2.34e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 1 MPRMTAAAAAVEILKIEGVSQAFGVPGAAINPFYRELKNV-GGIGHTLARHVEGASHMAEGYTRAkAGNIGVCIGTSGPA 79
Cdd:PRK08611 1 MAKIKAGEALVKLLQDWGIDHVYGIPGDSIDAVVDALRKEqDKIKFIQVRHEEVAALAAAAYAKL-TGKIGVCLSIGGPG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 80 GTDMITGLYSAIADSIPILCITGQAPVSKLHKEDFQAVDIASIAGPVTKKATTVLEAAQVPGVFQEAFHLMRSGRPGPVL 159
Cdd:PRK08611 80 AIHLLNGLYDAKMDHVPVLALAGQVTSDLLGTDFFQEVNLEKMFEDVAVYNHQIMSAENLPEIVNQAIRTAYEKKGVAVL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 160 I---DLPIDVQLTEIEFDPETYAPLPVYKPRATRAQAAKALGfllESQRPLIVAGGGIINAdaSDLLVEFAELVGVPVIS 236
Cdd:PRK08611 160 TipdDLPAQKIKDTTNKTVDTFRPTVPSPKPKDIKKAAKLIN---KAKKPVILAGLGAKHA--KEELLAFAEKAKIPIIH 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 237 TLMGWGTIPDDHQLA---AGMVGVQTAHRygnaTFLESDFVFGIGNRWAnrHTGYnLDAYTKGrtfVHVDIEPTQLGKIF 313
Cdd:PRK08611 235 TLPAKGIIPDDHPYSlgnLGKIGTKPAYE----AMQEADLLIMVGTNYP--YVDY-LPKKAKA---IQIDTDPANIGKRY 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 314 APDFGIASDAKAALelfieiaKELKAEGKLPDFSAWAASAQERKGS----LQRRTHFDDIPLKPQRVYEEMNKAFGPETR 389
Cdd:PRK08611 305 PVNVGLVGDAKKAL-------HQLTENIKHVEDRRFLEACQENMAKwwkwMEEDENNASTPIKPERVMAAIQKIADDDAV 377
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 390 YVTTIGLSQIAAAQFLHVYRPRNWINCGQAGPLGWTIPAAIGAATAEPETPIVALSGDYDFQFMIEELAVAAQHKVPYVH 469
Cdd:PRK08611 378 LSVDVGTVTVWSARYLNLGTNQKFIISSWLGTMGCGLPGAIAAKIAFPDRQAIAICGDGGFSMVMQDFVTAVKYKLPIVV 457
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 470 VLVNNAYLGLIR---QAQGGLgiNFEVNLEfenintpelcvyGVDHVKVAEGLGVKAIRVTDPDKLGEAFEEAKKlaqeF 546
Cdd:PRK08611 458 VVLNNQQLAFIKyeqQAAGEL--EYAIDLS------------DMDYAKFAEACGGKGYRVEKAEELDPAFEEALA----Q 519
|
....*....
gi 2429932465 547 QVPVVVEAI 555
Cdd:PRK08611 520 DKPVIIDVY 528
|
|
| PRK08199 |
PRK08199 |
thiamine pyrophosphate protein; Validated |
1-553 |
1.96e-70 |
|
thiamine pyrophosphate protein; Validated
Pssm-ID: 181285 [Multi-domain] Cd Length: 557 Bit Score: 237.08 E-value: 1.96e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 1 MPRMTAAAAAVEILKIEGVSQAFGVPG----AAINPFYRElknvGGIGHTLARHVEGASHMAEGYTRAkAGNIGVCIGTS 76
Cdd:PRK08199 5 PRARTGGQILVDALRANGVERVFCVPGesylAVLDALHDE----TDIRVIVCRQEGGAAMMAEAYGKL-TGRPGICFVTR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 77 GPAGTDMITGLYSAIADSIPILCITGQAPVSKLHKEDFQAVDIASIAGPVTKKATTVLEAAQVPGVFQEAFHLMRSGRPG 156
Cdd:PRK08199 80 GPGATNASIGVHTAFQDSTPMILFVGQVARDFREREAFQEIDYRRMFGPMAKWVAEIDDAARIPELVSRAFHVATSGRPG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 157 PVLIDLPIDVqLTEIefdpETYAPLPVYKPRATR---AQAAKALGFLLESQRPLIVAGGGIINADASDLLVEFAELVGVP 233
Cdd:PRK08199 160 PVVLALPEDV-LSET----AEVPDAPPYRRVAAApgaADLARLAELLARAERPLVILGGSGWTEAAVADLRAFAERWGLP 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 234 VISTLMGWGTIPDDHQLAAGMVGVQTAHRYGnATFLESDFVFGIGNRWANRHT-GYNL-DAYTKGRTFVHVDIEPTQLGK 311
Cdd:PRK08199 235 VACAFRRQDLFDNRHPNYAGDLGLGINPALA-ARIREADLVLAVGTRLGEVTTqGYTLlDIPVPRQTLVHVHPDAEELGR 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 312 IFAPDFGIASDAKAALELFIEIAKelkaegklPDFSAWAASAQERkgslqRRTHFDDIPLKPQ-------RVYEEMNKAF 384
Cdd:PRK08199 314 VYRPDLAIVADPAAFAAALAALEP--------PASPAWAEWTAAA-----HADYLAWSAPLPGpgavqlgEVMAWLRERL 380
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 385 GPETryVTTIGLSQIAAaqFLHVYRPRNWINcGQAGP----LGWTIPAAIGAATAEPETPIVALSGDYDFQFMIEELAVA 460
Cdd:PRK08199 381 PADA--IITNGAGNYAT--WLHRFFRFRRYR-TQLAPtsgsMGYGLPAAIAAKLLFPERTVVAFAGDGCFLMNGQELATA 455
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 461 AQHKVPYVHVLVNNAYLGLIRQAQgglginfE-------VNLEFENintpelcvygVDHVKVAEGLGVKAIRVTDPDKLG 533
Cdd:PRK08199 456 VQYGLPIIVIVVNNGMYGTIRMHQ-------EreypgrvSGTDLTN----------PDFAALARAYGGHGETVERTEDFA 518
|
570 580
....*....|....*....|
gi 2429932465 534 EAFEEakklAQEFQVPVVVE 553
Cdd:PRK08199 519 PAFER----ALASGKPALIE 534
|
|
| PRK06154 |
PRK06154 |
thiamine pyrophosphate-requiring protein; |
4-563 |
1.16e-69 |
|
thiamine pyrophosphate-requiring protein;
Pssm-ID: 235718 [Multi-domain] Cd Length: 565 Bit Score: 235.09 E-value: 1.16e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 4 MTAAAAAVEILKIEGVSQAFGVPgaaINPFYrELKNVGGIGHTLARHVEGASHMAEGYTRAKAG-NIGVCIGTSGPAGTD 82
Cdd:PRK06154 20 MKVAEAVAEILKEEGVELLFGFP---VNELF-DAAAAAGIRPVIARTERVAVHMADGYARATSGeRVGVFAVQYGPGAEN 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 83 MITGLYSAIADSIPILCITGQAPVSKLHKE-DFQAvdiASIAGPVTKKATTVLEAAQVPGVFQEAFHLMRSGRPGPVLID 161
Cdd:PRK06154 96 AFGGVAQAYGDSVPVLFLPTGYPRGSTDVApNFES---LRNYRHITKWCEQVTLPDEVPELMRRAFTRLRNGRPGPVVLE 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 162 LPIDVQLTEIEFDPETYAPLPVYKPRATRAQAAKALGFLLESQRPLIVAGGGIINADASDLLVEFAELVGVPVISTLMGW 241
Cdd:PRK06154 173 LPVDVLAEELDELPLDHRPSRRSRPGADPVEVVEAAALLLAAERPVIYAGQGVLYAQATPELKELAELLEIPVMTTLNGK 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 242 GTIPDDHQLAAGMVGV----QTAHrygnatFL-ESDFVFGIGNRWAnrHTGYNLdAYTKGRTFVHVDIEPTQLGKIFAPD 316
Cdd:PRK06154 253 SAFPEDHPLALGSGGRarpaTVAH------FLrEADVLFGIGCSLT--RSYYGL-PMPEGKTIIHSTLDDADLNKDYPID 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 317 FGIASDAKAALELFIEIAKE--LKAEGKLPDFSA-WAASAQERKGSLQRRTHFDDIPLKPQRVYEEMNKAFGPETRYVT- 392
Cdd:PRK06154 324 HGLVGDAALVLKQMIEELRRrvGPDRGRAQQVAAeIEAVRAAWLAKWMPKLTSDSTPINPYRVVWELQHAVDIKTVIITh 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 393 TIGLSQIAAAQFLHVYRPRNWINCGQAGPLGWTIPAAIGAATAEPETPIVALSGDYDFQFMIEELAVAAQHKVPYVHVLV 472
Cdd:PRK06154 404 DAGSPRDQLSPFYVASRPGSYLGWGKTTQLGYGLGLAMGAKLARPDALVINLWGDAAFGMTGMDFETAVRERIPILTILL 483
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 473 NNAYLGlirqaqgglGINFEVNLEFENINTPELcvyGVDHVKVAEGLGVKAIRVTDPDKLGEAFEEAKKLAQEFQvPVVV 552
Cdd:PRK06154 484 NNFSMG---------GYDKVMPVSTTKYRATDI---SGDYAAIARALGGYGERVEDPEMLVPALLRALRKVKEGT-PALL 550
|
570
....*....|.
gi 2429932465 553 EAILERITNIA 563
Cdd:PRK06154 551 EVITSEETALS 561
|
|
| PRK06112 |
PRK06112 |
acetolactate synthase catalytic subunit; Validated |
2-557 |
4.15e-69 |
|
acetolactate synthase catalytic subunit; Validated
Pssm-ID: 235700 [Multi-domain] Cd Length: 578 Bit Score: 234.27 E-value: 4.15e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 2 PRMTAAAAAVEILKIEGVSQAFG--VPGAAInpFYRELKNVGGIGHtlaRHVEGASHMAEGYTRAkAGNIGVCIGTSGPA 79
Cdd:PRK06112 12 LNGTVAHAIARALKRHGVEQIFGqsLPSALF--LAAEAIGIRQIAY---RTENAGGAMADGYARV-SGKVAVVTAQNGPA 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 80 GTDMITGLYSAIADSIPILCITGQAPVSKLHKEDFQAVDIASIAGPVTKKATTVLEAAQVPGVFQEAFHLMRSGRPGPVL 159
Cdd:PRK06112 86 ATLLVAPLAEALKASVPIVALVQDVNRDQTDRNAFQELDHIALFQSCTKWVRRVTVAERIDDYVDQAFTAATSGRPGPVV 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 160 IDLPIDVQLTEIEF----DPETYAPLPVYKPRATRAQAAKALGFLLESQRPLIVAGGGIINADASDLLVEFAELVGVPVI 235
Cdd:PRK06112 166 LLLPADLLTAAAAApaapRSNSLGHFPLDRTVPAPQRLAEAASLLAQAQRPVVVAGGGVHISGASAALAALQSLAGLPVA 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 236 STLMGWGTIPDDHQLAAGMV----GVQTAHRYGNATFLESDFVFGIGNRwANRHTGYNLDAYTKGRTFVHVDIEPTQLGK 311
Cdd:PRK06112 246 TTNMGKGAVDETHPLSLGVVgslmGPRSPGRHLRDLVREADVVLLVGTR-TNQNGTDSWSLYPEQAQYIHIDVDGEEVGR 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 312 IFAPdFGIASDAKAALELFIEIAKELKAEGKLPDFSAWAAS-AQERKGSLQRRTHF---DDIPLKPQRVYEEMNKAFGPE 387
Cdd:PRK06112 325 NYEA-LRLVGDARLTLAALTDALRGRDLAARAGRRAALEPAiAAGREAHREDSAPValsDASPIRPERIMAELQAVLTGD 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 388 TRYVTTIGLSQIAAAQFLHVYRP--RNWINCGQAGpLGWTIPAAIGAATAEPETPIVALSGDYDFQFMIEELAVAAQHKV 465
Cdd:PRK06112 404 TIVVADASYSSIWVANFLTARRAgmRFLTPRGLAG-LGWGVPMAIGAKVARPGAPVICLVGDGGFAHVWAELETARRMGV 482
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 466 PYVHVLVNNAYLGLIRQAQGGLGINFEVNLEFEnintpelcvyGVDHVKVAEGLGVKAIRVTDPDKLGEAFEEAKKLaqe 545
Cdd:PRK06112 483 PVTIVVLNNGILGFQKHAETVKFGTHTDACHFA----------AVDHAAIARACGCDGVRVEDPAELAQALAAAMAA--- 549
|
570
....*....|..
gi 2429932465 546 fQVPVVVEAILE 557
Cdd:PRK06112 550 -PGPTLIEVITD 560
|
|
| PRK07525 |
PRK07525 |
sulfoacetaldehyde acetyltransferase; Validated |
1-558 |
1.20e-59 |
|
sulfoacetaldehyde acetyltransferase; Validated
Pssm-ID: 236042 [Multi-domain] Cd Length: 588 Bit Score: 208.70 E-value: 1.20e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 1 MPRMTAAAAAVEILKIEGVSQAFGVPGAAINPFyRELKNVGGIGHTLARHVEGASHMAEGYTRAkAGNIGVCIGTSGPAG 80
Cdd:PRK07525 3 KMKMTPSEAFVETLQAHGITHAFGIIGSAFMDA-SDLFPPAGIRFIDVAHEQNAGHMADGYTRV-TGRMGMVIGQNGPGI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 81 TDMITGLYSAIADSIPILCITGQAPVSKLHKEDFQAVDIASIAGPVTKKATTVLEAAQVPGVFQEAFHLMRSGRpGPVLI 160
Cdd:PRK07525 81 TNFVTAVATAYWAHTPVVLVTPQAGTKTIGQGGFQEAEQMPMFEDMTKYQEEVRDPSRMAEVLNRVFDKAKRES-GPAQI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 161 DLPIDVQLTEIefDPETYAPLPVYKPRATRAQAAKALGFLLESQRPLIVAGGGIINADASDLLVEFAELVGVPVISTLMG 240
Cdd:PRK07525 160 NIPRDYFYGVI--DVEIPQPVRLERGAGGEQSLAEAAELLSEAKFPVILSGAGVVLSDAIEECKALAERLDAPVACGYLH 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 241 WGTIPDDHQLAAGMVGVQTAhRYGNATFLESDFVFGIGNRWANRHT--GYNLDAYTKGRTFVHVDIEPTQLGKIFAPDFG 318
Cdd:PRK07525 238 NDAFPGSHPLWVGPLGYNGS-KAAMELIAKADVVLALGTRLNPFGTlpQYGIDYWPKDAKIIQVDINPDRIGLTKKVSVG 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 319 IASDAKAAlelfieiAKELKAegKLPDFSAWAASAQERKGSLQRR-----------THFDDIP---------------LK 372
Cdd:PRK07525 317 ICGDAKAV-------ARELLA--RLAERLAGDAGREERKALIAAEksaweqelsswDHEDDDPgtdwneeararkpdyMH 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 373 PQRVYEEMNKAFGPETRYVTTIG-LSQIAAAqFLHVYRPRNWINCGQAGPLGWTIPAAIGAATAEPETPIVALSGDYDFQ 451
Cdd:PRK07525 388 PRQALREIQKALPEDAIVSTDIGnNCSIANS-YLRFEKGRKYLAPGSFGNCGYAFPAIIGAKIACPDRPVVGFAGDGAWG 466
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 452 FMIEELAVAAQHKVPYVHVLVNNAYLGLIRQAQGGLginFEVNLEFENINTPelcvygVDHVKVAEGLGVKAIRVTDPDK 531
Cdd:PRK07525 467 ISMNEVMTAVRHNWPVTAVVFRNYQWGAEKKNQVDF---YNNRFVGTELDNN------VSYAGIAEAMGAEGVVVDTQEE 537
|
570 580
....*....|....*....|....*..
gi 2429932465 532 LGEAFEEAKKlAQEFQVPVVVEAILER 558
Cdd:PRK07525 538 LGPALKRAID-AQNEGKTTVIEIMCNQ 563
|
|
| PRK06457 |
PRK06457 |
pyruvate dehydrogenase; Provisional |
5-557 |
9.39e-51 |
|
pyruvate dehydrogenase; Provisional
Pssm-ID: 180570 [Multi-domain] Cd Length: 549 Bit Score: 183.88 E-value: 9.39e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 5 TAAAAAVEILKIEGVSQAFGVPGAAINPFYRELKNvGGIGHTLARHVEGAShMAEGYTRAKAGNIGVCIGTSGPAGTDMI 84
Cdd:PRK06457 3 SVAEVIIRVLEDNGIQRIYGIPGDSIDPLVDAIRK-SKVKYVQVRHEEGAA-LAASVEAKITGKPSACMGTSGPGSIHLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 85 TGLYSAIADSIPILCITGQAPVSKLHKEDFQAVDIASIAGPVTKKATTVLEAAQVPGVFQEAFHLMRSGRpGPVLIDLPI 164
Cdd:PRK06457 81 NGLYDAKMDHAPVIALTGQVESDMIGHDYFQEVNLTKLFDDVAVFNQILINPENAEYIIRRAIREAISKR-GVAHINLPV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 165 DVQLTEIEFDPETYAPLPVYKpraTRAQAAKALGFLLESQRPLIVAGGGIInaDASDLLVEFAELVGVPVISTLMGWGTI 244
Cdd:PRK06457 160 DILRKSSEYKGSKNTEVGKVK---YSIDFSRAKELIKESEKPVLLIGGGTR--GLGKEINRFAEKIGAPIIYTLNGKGIL 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 245 PDDHQLAAGMVG-------VQTAHRYGNATFLESDFVFGignrwanrhTGYNLDAytkgrTFVHVDIEPTQLGKIFAPDF 317
Cdd:PRK06457 235 PDLDPKVMGGIGllgtkpsIEAMDKADLLIMLGTSFPYV---------NFLNKSA-----KVIQVDIDNSNIGKRLDVDL 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 318 GIASDAKAALELFIEIAKELKAEGKLPDFSAWAASAQERKGSLqrrthfdDIPLKPQRVYEEMNKAFGPETRYVTTIGLS 397
Cdd:PRK06457 301 SYPIPVAEFLNIDIEEKSDKFYEELKGKKEDWLDSISKQENSL-------DKPMKPQRVAYIVSQKCKKDAVIVTDTGNV 373
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 398 QIAAAQFLHVYRPRNWINCGQAGPLGWTIPAAIGAATA-EPETPIVALSGDYDFQFMIEELAVAAQHKVPYVHVLVNNAY 476
Cdd:PRK06457 374 TMWTARHFRASGEQTFIFSAWLGSMGIGVPGSVGASFAvENKRQVISFVGDGGFTMTMMELITAKKYDLPVKIIIYNNSK 453
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 477 LGLIRqaqgglginfevnLEFENINTPELCV--YGVDHVKVAEGLGVKAIRVTDPDKLGEAFEEAKklaqEFQVPVVVEA 554
Cdd:PRK06457 454 LGMIK-------------FEQEVMGYPEWGVdlYNPDFTKIAESIGFKGFRLEEPKEAEEIIEEFL----NTKGPAVLDA 516
|
...
gi 2429932465 555 ILE 557
Cdd:PRK06457 517 IVD 519
|
|
| TPP_PYR_POX_like |
cd07035 |
Pyrimidine (PYR) binding domain of POX and related proteins; Thiamine pyrophosphate (TPP ... |
9-164 |
1.69e-50 |
|
Pyrimidine (PYR) binding domain of POX and related proteins; Thiamine pyrophosphate (TPP family), pyrimidine (PYR) binding domain of pyruvate oxidase (POX) and related protiens subfamily. The PYR domain is found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. TPP binds in the cleft formed by a PYR domain and a PP domain. The PYR domain, binds the aminopyrimidine ring of TPP, the PP domain binds the diphosphate residue. A polar interaction between the conserved glutamate of the PYR domain and the N1' of the TPP aminopyrimidine ring is shared by most TPP-dependent enzymes, and participates in the activation of TPP. For glyoxylate carboligase, which belongs to this subfamily, but lacks this conserved glutamate, the rate of the initial TPP activation step is reduced but the ensuing steps of the enzymic reaction proceed efficiently. The PYR and PP domains have a common fold, but do not share strong sequence conservation. The PP domain is not included in this sub-family. Most TPP-dependent enzymes have the PYR and PP domains on the same subunit although these domains can be alternatively arranged in the primary structure. TPP-dependent enzymes are multisubunit proteins, the smallest catalytic unit being a dimer-of-active sites, for many the active sites lie between PP and PYR domains on different subunits. POX decarboxylates pyruvate, producing hydrogen peroxide and the energy-storage metabolite acetylphosphate. This subfamily includes pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC catalyzes the conversion of pyruvate to acetaldehyde and CO2 in alcoholic fermentation. IPDC plays a role in the indole-3-pyruvic acid (IPA) pathway in plants and various plant-associated bacteria, it catalyzes the decarboxylation of IPA to IAA. This subfamily also includes the large catalytic subunit of acetohydroxyacid synthase (AHAS). AHAS catalyzes the condensation of two molecules of pyruvate to give the acetohydroxyacid, 2-acetolactate, a precursor of the branched chain amino acids, valine and leucine. AHAS also catalyzes the condensation of pyruvate and 2-ketobutyrate to form 2-aceto-2-hydroxybutyrate in isoleucine biosynthesis. Methanococcus jannaschii sulfopyruvate decarboxylase (MjComDE) and phosphonopyruvate decarboxylase (PpyrDc) also belong to this subfamily. PpyrDc is a homotrimeric enzyme having the PP and PYR domains tandemly arranged on the same subunit. It functions in the biosynthesis of C-P compounds such as bialaphos tripeptide in Streptomyces hygroscopicus. MjComDE is a dodecamer having the PYR and PP domains on different subunits, it has six alpha (PYR/ComD) subunits and six beta (PP/ComE) subunits. MjComDE catalyzes the decarboxylation of sulfopyruvic acid to sulfoacetaldehyde in the coenzyme M pathway.
Pssm-ID: 132918 [Multi-domain] Cd Length: 155 Bit Score: 171.18 E-value: 1.69e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 9 AAVEILKIEGVSQAFGVPGAAINPFYRELKNvGGIGHTLARHVEGASHMAEGYTRAKaGNIGVCIGTSGPAGTDMITGLY 88
Cdd:cd07035 2 ALVEALKAEGVDHVFGVPGGAILPLLDALAR-SGIRYILVRHEQGAVGMADGYARAT-GKPGVVLVTSGPGLTNAVTGLA 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2429932465 89 SAIADSIPILCITGQAPVSKLHKEDFQAVDIASIAGPVTKKATTVLEAAQVPGVFQEAFHLMRSGRPGPVLIDLPI 164
Cdd:cd07035 80 NAYLDSIPLLVITGQRPTAGEGRGAFQEIDQVALFRPITKWAYRVTSPEEIPEALRRAFRIALSGRPGPVALDLPK 155
|
|
| PRK08617 |
PRK08617 |
acetolactate synthase AlsS; |
4-553 |
1.31e-48 |
|
acetolactate synthase AlsS;
Pssm-ID: 236312 [Multi-domain] Cd Length: 552 Bit Score: 177.74 E-value: 1.31e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 4 MTAAAAAVEILKIEGVSQAFGVPGAAINPFYRELKNvGGIGHTLARHVEGASHMAEGYTRAkAGNIGVCIGTSGPAGTDM 83
Cdd:PRK08617 5 KYGADLVVDSLINQGVKYVFGIPGAKIDRVFDALED-SGPELIVTRHEQNAAFMAAAIGRL-TGKPGVVLVTSGPGVSNL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 84 ITGLYSAIADSIPILCITGQAPVSKLHKEDFQAVDIASIAGPVTKKATTVLEAAQVPGVFQEAFHLMRSGRPGPVLIDLP 163
Cdd:PRK08617 83 ATGLVTATAEGDPVVAIGGQVKRADRLKRTHQSMDNVALFRPITKYSAEVQDPDNLSEVLANAFRAAESGRPGAAFVSLP 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 164 IDVQLTEIEFDPETYAPLPVYKPrATRAQAAKALGFLLESQRPLIVAGGGIINADASDLLVEFAELVGVPVISTLMGWGT 243
Cdd:PRK08617 163 QDVVDAPVTSKAIAPLSKPKLGP-ASPEDINYLAELIKNAKLPVLLLGMRASSPEVTAAIRRLLERTNLPVVETFQAAGV 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 244 IPDDHQ-LAAGMVGV---QTahryGNATFLESDFVFGIgnrwanrhtGYNLDAY-------TKGRTFVHVDIEPTQLGKI 312
Cdd:PRK08617 242 ISRELEdHFFGRVGLfrnQP----GDELLKKADLVITI---------GYDPIEYeprnwnsEGDATIIHIDVLPAEIDNY 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 313 FAPDfgiasdakaaLELFIEIAKELKAEGKLPDFSAWAASAQERKGSLQRRTHFDDIP--------LKPQRVYEEMNKAF 384
Cdd:PRK08617 309 YQPE----------RELIGDIAATLDLLAEKLDGLSLSPQSLEILEELRAQLEELAERparleegaVHPLRIIRALQDIV 378
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 385 GPETRYVTTIGLSQIAAAQFLHVYRPRNW-INCGQAgPLGWTIPAAIGAATAEPETPIVALSGDYDFQFMIEELAVAAQH 463
Cdd:PRK08617 379 TDDTTVTVDVGSHYIWMARYFRSYEPRHLlFSNGMQ-TLGVALPWAIAAALVRPGKKVVSVSGDGGFLFSAMELETAVRL 457
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 464 KVPYVHVL-VNNAYlglirqaqgglginfevNL-EFEnintpELCVYG---------VDHVKVAEGLGVKAIRVTDPDKL 532
Cdd:PRK08617 458 KLNIVHIIwNDGHY-----------------NMvEFQ-----EEMKYGrssgvdfgpVDFVKYAESFGAKGLRVTSPDEL 515
|
570 580
....*....|....*....|.
gi 2429932465 533 GEAFEEAkkLAQEfqVPVVVE 553
Cdd:PRK08617 516 EPVLREA--LATD--GPVVID 532
|
|
| PRK05858 |
PRK05858 |
acetolactate synthase; |
2-539 |
3.33e-47 |
|
acetolactate synthase;
Pssm-ID: 235629 [Multi-domain] Cd Length: 542 Bit Score: 173.75 E-value: 3.33e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 2 PRMTAAAAAVEILKIEGVSQAFGVPGAAINPFYRELKNvGGIGHTLARHVEGASHMAEGY---TRAKagniGVCIGTSGP 78
Cdd:PRK05858 3 QTGHAGRLAARRLKAHGVDTMFTLSGGHLFPLYDGARE-EGIRLIDVRHEQTAAFAAEAWaklTRVP----GVAVLTAGP 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 79 AGTDMITGLYSAIADSIPILCITGQAPVSKLHKEDFQAVDIASIAGPVTKKATTVLEAAQVPGVFQEAFHLMRSGRPGPV 158
Cdd:PRK05858 78 GVTNGMSAMAAAQFNQSPLVVLGGRAPALRWGMGSLQEIDHVPFVAPVTKFAATAQSAENAGRLVDQALQAAVTPHRGPV 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 159 LIDLPIDVQLTEIEFD--PETYAPLPVyKPRATRAQAAKALGFLLESQRPLIVAGGGIINADASDLLVEFAELVGVPVIS 236
Cdd:PRK05858 158 FVDFPMDHAFSMADDDgrPGALTELPA-GPTPDPDALARAAGLLAEAQRPVIMAGTDVWWGHAEAALLRLAEELGIPVLM 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 237 TLMGWGTIPDDHQLAAGmvgvqtahRYGNATFLESDFVFGIGNRWANRhTGYNLdaYTKGRTFVHVDIEPTQLGKIFAPD 316
Cdd:PRK05858 237 NGMGRGVVPADHPLAFS--------RARGKALGEADVVLVVGVPMDFR-LGFGV--FGGTAQLVHVDDAPPQRAHHRPVA 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 317 FGIASDAKAALELFIEiakelkAEGKLPDFSAW-------AASAQERKGSLQRRthfDDIPLKPQRVYEEMNKAFGPETR 389
Cdd:PRK05858 306 AGLYGDLSAILSALAG------AGGDRTDHQGWieelrtaETAARARDAAELAD---DRDPIHPMRVYGELAPLLDRDAI 376
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 390 YVTTIGLSQIAAAQFLHVYRPRNWINCGQAGPLGWTIPAAIGAATAEPETPIVALSGDYDFQFMIEELAVAAQHKVPYVH 469
Cdd:PRK05858 377 VIGDGGDFVSYAGRYIDPYRPGCWLDPGPFGCLGTGPGYALAARLARPSRQVVLLQGDGAFGFSLMDVDTLVRHNLPVVS 456
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 470 VLVNNAYLGLIRQaqgglginfevnlefenintPELCVYGVDHV----------KVAEGLGVKAIRVTDPDKLGEAFEEA 539
Cdd:PRK05858 457 VIGNNGIWGLEKH--------------------PMEALYGYDVAadlrpgtrydEVVRALGGHGELVTVPAELGPALERA 516
|
|
| PRK07064 |
PRK07064 |
thiamine pyrophosphate-binding protein; |
5-553 |
6.51e-47 |
|
thiamine pyrophosphate-binding protein;
Pssm-ID: 180820 [Multi-domain] Cd Length: 544 Bit Score: 172.87 E-value: 6.51e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 5 TAAAAAVEILKIEGVSQAFGVPGAAINPFYRELKNVGGIGHTLARHVEGASHMAEGYTRAKaGNIGVCIGTSGPAGTDMI 84
Cdd:PRK07064 4 TVGELIAAFLEQCGVKTAFGVISIHNMPILDAIGRRGKIRFVPARGEAGAVNMADAHARVS-GGLGVALTSTGTGAGNAA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 85 TGLYSAIADSIPILCITGQ-------APVSKLHkedfQAVDIASIAGPVTKKATTVLEAAQVPGVFQEAFHLMRSGRPGP 157
Cdd:PRK07064 83 GALVEALTAGTPLLHITGQietpyldQDLGYIH----EAPDQLTMLRAVSKAAFRVRSAETALATIREAVRVALTAPTGP 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 158 VLIDLPIDVQLTEIEFdPETYAPLPVYKPRATRAQAAKALGFLLESQRPLIVAGGGIINADAsdllvEFAELV--GVPVI 235
Cdd:PRK07064 159 VSVEIPIDIQAAEIEL-PDDLAPVHVAVPEPDAAAVAELAERLAAARRPLLWLGGGARHAGA-----EVKRLVdlGFGVV 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 236 STLMGWGTIPDDHQLAAGMVGVQTAhryGNATFLESDFVFGIGNRWANRHTG-YNLDAytkGRTFVHVDIEPTQLGKIFA 314
Cdd:PRK07064 233 TSTQGRGVVPEDHPASLGAFNNSAA---VEALYKTCDLLLVVGSRLRGNETLkYSLAL---PRPLIRVDADAAADGRGYP 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 315 PDFGIASDAKAALELFIEiakelKAEGKLPDFSAWAASAQERKgsLQRRTHFDDiPLKPQRVY-EEMNKAFGPETRYVTT 393
Cdd:PRK07064 307 NDLFVHGDAARVLARLAD-----RLEGRLSVDPAFAADLRAAR--EAAVADLRK-GLGPYAKLvDALRAALPRDGNWVRD 378
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 394 IGLSQIA-AAQFLHVYRPRNWINcGQAGPLGWTIPAAIGAATAEPETPIVALSGDYDFQFMIEELAVAAQHKVPYVHVLV 472
Cdd:PRK07064 379 VTISNSTwGNRLLPIFEPRANVH-ALGGGIGQGLAMAIGAALAGPGRKTVGLVGDGGLMLNLGELATAVQENANMVIVLM 457
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 473 NNAYLGLIRQAQGGlgiNFEVNLEFENINTPelcvygvDHVKVAEGLGVKAIRVTDPDKLGEAFEEAkkLAqeFQVPVVV 552
Cdd:PRK07064 458 NDGGYGVIRNIQDA---QYGGRRYYVELHTP-------DFALLAASLGLPHWRVTSADDFEAVLREA--LA--KEGPVLV 523
|
.
gi 2429932465 553 E 553
Cdd:PRK07064 524 E 524
|
|
| TPP_enzyme_N |
pfam02776 |
Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; |
6-172 |
3.18e-46 |
|
Thiamine pyrophosphate enzyme, N-terminal TPP binding domain;
Pssm-ID: 460690 [Multi-domain] Cd Length: 169 Bit Score: 160.48 E-value: 3.18e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 6 AAAAAVEILKIEGVSQAFGVPGAAINPFYRELKNVGGIGHTLARHVEGASHMAEGYTRAKaGNIGVCIGTSGPAGTDMIT 85
Cdd:pfam02776 1 GAEALADVLKALGVDTVFGVPGGHILPLLDALAKSPGIRYVLTRHEQGAAFAADGYARAT-GKPGVVLVTSGPGATNALT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 86 GLYSAIADSIPILCITGQAPVSKLHKEDFQA-VDIASIAGPVTKKATTVLEAAQVPGVFQEAFHLMRSGRPGPVLIDLPI 164
Cdd:pfam02776 80 GLANAYVDSVPLLVISGQRPRSLVGRGALQQeLDQLALFRPVTKWAVRVTSADEIPEVLRRAFRAALSGRPGPVYLEIPL 159
|
....*...
gi 2429932465 165 DVQLTEIE 172
Cdd:pfam02776 160 DVLLEEVD 167
|
|
| TPP_enzyme_C |
pfam02775 |
Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; |
394-554 |
2.14e-43 |
|
Thiamine pyrophosphate enzyme, C-terminal TPP binding domain;
Pssm-ID: 460689 [Multi-domain] Cd Length: 151 Bit Score: 151.97 E-value: 2.14e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 394 IGLSQIAAAQFLHVYRPRNWINCGQAGPLGWTIPAAIGAATAEPETPIVALSGDYDFQFMIEELAVAAQHKVPYVHVLVN 473
Cdd:pfam02775 2 IGCHQMWAAQYYRFRPPRRYLTSGGLGTMGYGLPAAIGAKLARPDRPVVAIAGDGGFQMNLQELATAVRYNLPITVVVLN 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 474 NAYLGLIRQAQGGLGINFEVNLEFENINtpelcvyGVDHVKVAEGLGVKAIRVTDPDKLGEAFEEAKklaqEFQVPVVVE 553
Cdd:pfam02775 82 NGGYGMTRGQQTPFGGGRYSGPSGKILP-------PVDFAKLAEAYGAKGARVESPEELEEALKEAL----EHDGPALID 150
|
.
gi 2429932465 554 A 554
Cdd:pfam02775 151 V 151
|
|
| TPP_enzymes |
cd00568 |
Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic ... |
375-555 |
1.86e-40 |
|
Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and the branched chain alpha-keto acid dehydrogenase complexes.
Pssm-ID: 238318 [Multi-domain] Cd Length: 168 Bit Score: 144.71 E-value: 1.86e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 375 RVYEEMNKAFGPETRYVTTIGLSQIAAAQFLHVYRPRNWINCGQAGPLGWTIPAAIGAATAEPETPIVALSGDYDFQFMI 454
Cdd:cd00568 1 RVLAALRAALPEDAIVVNDAGNSAYWAYRYLPLRRGRRFLTSTGFGAMGYGLPAAIGAALAAPDRPVVCIAGDGGFMMTG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 455 EELAVAAQHKVPYVHVLVNNAYLGLIRQAQGGLGINFEVNLEFENIntpelcvygvDHVKVAEGLGVKAIRVTDPDKLGE 534
Cdd:cd00568 81 QELATAVRYGLPVIVVVFNNGGYGTIRMHQEAFYGGRVSGTDLSNP----------DFAALAEAYGAKGVRVEDPEDLEA 150
|
170 180
....*....|....*....|.
gi 2429932465 535 AFEEakklAQEFQVPVVVEAI 555
Cdd:cd00568 151 ALAE----ALAAGGPALIEVK 167
|
|
| PRK08327 |
PRK08327 |
thiamine pyrophosphate-requiring protein; |
1-558 |
3.75e-40 |
|
thiamine pyrophosphate-requiring protein;
Pssm-ID: 236243 [Multi-domain] Cd Length: 569 Bit Score: 154.39 E-value: 3.75e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 1 MPRMTAAAAAVEILKIEGVSQAFGVPGAAINPFYRELKNVGGIGHTLAR-----HVEGASHMAEGYT----RAKAGNIGV 71
Cdd:PRK08327 4 LTMYTAAELFLELLKELGVDYIFINSGTDYPPIIEAKARARAAGRPLPEfvicpHEIVAISMAHGYAlvtgKPQAVMVHV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 72 CIGTSGPAGtdmitGLYSAIADSIPILCITGQAPVSKL----HKEDF-----QAVDIASIAGPVTKKATTVLEAAQVPGV 142
Cdd:PRK08327 84 DVGTANALG-----GVHNAARSRIPVLVFAGRSPYTEEgelgSRNTRihwtqEMRDQGGLVREYVKWDYEIRRGDQIGEV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 143 FQEAFHLMRSGRPGPVLIDLPIDVqLTEiEFDPETYAP---LPVYKPRATRAQAAKALGFLLESQRPLIVAGGGIINADA 219
Cdd:PRK08327 159 VARAIQIAMSEPKGPVYLTLPREV-LAE-EVPEVKADAgrqMAPAPPAPDPEDIARAAEMLAAAERPVIITWRAGRTAEG 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 220 SDLLVEFAELVGVPVISTLMGWGTIPDDHQLAAGMVGvqtahrygNATFLESDFVFGIGNR--WANRHTGYNLDAytkgr 297
Cdd:PRK08327 237 FASLRRLAEELAIPVVEYAGEVVNYPSDHPLHLGPDP--------RADLAEADLVLVVDSDvpWIPKKIRPDADA----- 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 298 TFVHVDIEPTQlGKI----FAPDFGIASDAKAALELFIEIAKELKAEGKLPDFSAWAASAQER-KGSLQRRTHF----DD 368
Cdd:PRK08327 304 RVIQIDVDPLK-SRIplwgFPCDLCIQADTSTALDQLEERLKSLASAERRRARRRRAAVRELRiRQEAAKRAEIerlkDR 382
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 369 IPLKPQRVYEEMNKAFGPETRYVTTIGlsqiAAAQFLHVYRPRNWINCGQAGPLGWTIPAAIGAATAEPETPIVALSGDY 448
Cdd:PRK08327 383 GPITPAYLSYCLGEVADEYDAIVTEYP----FVPRQARLNKPGSYFGDGSAGGLGWALGAALGAKLATPDRLVIATVGDG 458
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 449 DFQFMIEE--LAVAAQHKVPYVHVLVNNA-YL------------GLIRQAQGGLGINFEVNLEFEnintpelcvygvdhv 513
Cdd:PRK08327 459 SFIFGVPEaaHWVAERYGLPVLVVVFNNGgWLavkeavlevypeGYAARKGTFPGTDFDPRPDFA--------------- 523
|
570 580 590 600
....*....|....*....|....*....|....*....|....*
gi 2429932465 514 KVAEGLGVKAIRVTDPDKLGEAFEEAKKLAQEFQVPVVVEAILER 558
Cdd:PRK08327 524 KIAEAFGGYGERVEDPEELKGALRRALAAVRKGRRSAVLDVIVDR 568
|
|
| TPP_AHAS |
cd02015 |
Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding ... |
371-562 |
3.07e-39 |
|
Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the acetohydroxyacid, 2-acetolactate. 2-Acetolactate is the precursor of the branched chain amino acids, valine and leucine. AHAS also catalyzes the condensation of pyruvate and 2-ketobutyrate to form 2-aceto-2-hydroxybutyrate in isoleucine biosynthesis. In addition to requiring TPP and a divalent metal ion as cofactors, AHAS requires FAD.
Pssm-ID: 238973 [Multi-domain] Cd Length: 186 Bit Score: 141.87 E-value: 3.07e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 371 LKPQRVYEEMNKAFGPETRYVTTIGLSQIAAAQFLHVYRPRNWINCGQAGPLGWTIPAAIGAATAEPETPIVALSGDYDF 450
Cdd:cd02015 1 IKPQEVIKELSELTPGDAIVTTDVGQHQMWAAQYYRFKKPRSWLTSGGLGTMGFGLPAAIGAKVARPDKTVICIDGDGSF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 451 QFMIEELAVAAQHKVPYVHVLVNNAYLGLIRQAQgglginfevNLEFENINTPELCVYGVDHVKVAEGLGVKAIRVTDPD 530
Cdd:cd02015 81 QMNIQELATAAQYNLPVKIVILNNGSLGMVRQWQ---------ELFYEGRYSHTTLDSNPDFVKLAEAYGIKGLRVEKPE 151
|
170 180 190
....*....|....*....|....*....|..
gi 2429932465 531 KLGEAFEEAKklaqEFQVPVVVEAILERITNI 562
Cdd:cd02015 152 ELEAALKEAL----ASDGPVLLDVLVDPEENV 179
|
|
| TPP_enzyme_M |
pfam00205 |
Thiamine pyrophosphate enzyme, central domain; The central domain of TPP enzymes contains a ... |
194-328 |
6.95e-38 |
|
Thiamine pyrophosphate enzyme, central domain; The central domain of TPP enzymes contains a 2-fold Rossman fold.
Pssm-ID: 425523 [Multi-domain] Cd Length: 137 Bit Score: 136.54 E-value: 6.95e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 194 AKALGFLLESQRPLIVAGGGIINADASDLLVEFAELVGVPVISTLMGWGTIPDDHQLAAGMVGVqTAHRYGNATFLESDF 273
Cdd:pfam00205 2 EKAAELLKKAKRPVILAGGGVRRSGASEELRELAEKLGIPVVTTLMGKGAFPEDHPLYLGMLGM-HGTPAANEALEEADL 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 2429932465 274 VFGIGNRWANRHTGYNLDAYTKGRTFVHVDIEPTQLGKIFAPDFGIASDAKAALE 328
Cdd:pfam00205 81 VLAVGARFDDIRTTGKLPEFAPDAKIIHIDIDPAEIGKNYPVDVPIVGDAKETLE 135
|
|
| PRK09124 |
PRK09124 |
ubiquinone-dependent pyruvate dehydrogenase; |
5-576 |
1.91e-36 |
|
ubiquinone-dependent pyruvate dehydrogenase;
Pssm-ID: 181661 [Multi-domain] Cd Length: 574 Bit Score: 143.59 E-value: 1.91e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 5 TAAAAAVEILKIEGVSQAFGVPGAAINPFYRELKNVGGIGHTLARHVEGAShMAEGYTRAKAGNIGVCIGTSGPAGTDMI 84
Cdd:PRK09124 4 TVADYIAKTLEQAGVKRIWGVTGDSLNGLSDSLRRMGTIEWMHTRHEEVAA-FAAGAEAQLTGELAVCAGSCGPGNLHLI 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 85 TGLYSAIADSIPILCITGQAPVSKLHKEDFQAVDIASIAGPVTKKATTVLEAAQVPGVFQEAfhlMRS--GRPGPVLIDL 162
Cdd:PRK09124 83 NGLFDCHRNHVPVLAIAAHIPSSEIGSGYFQETHPQELFRECSHYCELVSNPEQLPRVLAIA---MRKaiLNRGVAVVVL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 163 PIDVQLTEIEFDPE---TYAPLPVYKPRATRAQAAKALgfLLESQRPLIVAGGGIinADASDLLVEFAELVGVPVISTLM 239
Cdd:PRK09124 160 PGDVALKPAPERATphwYHAPQPVVTPAEEELRKLAAL--LNGSSNITLLCGSGC--AGAHDELVALAETLKAPIVHALR 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 240 GWGTIPDDHQLAAGMVGVqTAHRYGNATFLESDFVFGIGNRWANRhtgynlDAYTKGRTFVHVDIEPTQLGKIFAPDFGI 319
Cdd:PRK09124 236 GKEHVEYDNPYDVGMTGL-IGFSSGYHAMMNCDTLLMLGTDFPYR------QFYPTDAKIIQIDINPGSLGRRSPVDLGL 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 320 ASDAKAALELFIEIAKELKAEGKLPDFSAWAASAQERKGSLQRRTHfDDIPLKPQRVYEEMNKAFGPETRYVTTIGLSQI 399
Cdd:PRK09124 309 VGDVKATLAALLPLLEEKTDRKFLDKALEHYRKARKGLDDLAVPSD-GGKPIHPQYLARQISEFAADDAIFTCDVGTPTV 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 400 AAAQFLHVYRPRNWINCGQAGPLGWTIPAAIGAATAEPETPIVALSGDYDFQFMIEELAVAAQHKVPYVHVLVNNAYLGL 479
Cdd:PRK09124 388 WAARYLKMNGKRRLLGSFNHGSMANAMPQALGAQAAHPGRQVVALSGDGGFSMLMGDFLSLVQLKLPVKIVVFNNSVLGF 467
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 480 IRQAQGGLGInFEVNLEFENintpelcvygVDHVKVAEGLGVKAIRVTDPDKLGEAFEEAkkLAQefQVPVVVEAILERi 559
Cdd:PRK09124 468 VAMEMKAGGY-LTDGTDLHN----------PDFAAIAEACGITGIRVEKASELDGALQRA--FAH--DGPALVDVVTAK- 531
|
570
....*....|....*..
gi 2429932465 560 TNIAMSKTVDMSDVTEF 576
Cdd:PRK09124 532 QELAMPPQIKLEQAKGF 548
|
|
| PRK09259 |
PRK09259 |
putative oxalyl-CoA decarboxylase; Validated |
11-539 |
3.94e-35 |
|
putative oxalyl-CoA decarboxylase; Validated
Pssm-ID: 236433 [Multi-domain] Cd Length: 569 Bit Score: 139.74 E-value: 3.94e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 11 VEILKIEGVSQAFGVPGAAINPFYReLKNVGGIGHTLARHVEGASHMA--EGYTRAKAGnigVCIGTSGPAGTDMITGLY 88
Cdd:PRK09259 17 IDALKLNGIDTIYGVVGIPITDLAR-LAQAEGIRYIGFRHEQSAGNAAaaAGFLTQKPG---VCLTVSAPGFLNGLTALA 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 89 SAIADSIPILCITGQA--PVSKLHKEDFQAVDIASIAGPVTKKATTVLEAAQVPGVFQEAFHLMRSGRPGPVLIDLPIDV 166
Cdd:PRK09259 93 NATTNCFPMIMISGSSerEIVDLQQGDYEELDQLNAAKPFCKAAFRVNRAEDIGIGVARAIRTAVSGRPGGVYLDLPAKV 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 167 QLTEIEFDPetyAPLPVYK-----PRATRAQAA--KALGFLLESQRPLIVAGGGIINADASDLLVEFAELVGVPVISTLM 239
Cdd:PRK09259 173 LAQTMDADE---ALTSLVKvvdpaPAQLPAPEAvdRALDLLKKAKRPLIILGKGAAYAQADEQIREFVEKTGIPFLPMSM 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 240 GWGTIPDDHQLAAGmvgvqtAHRygNATFLESDFVFGIGNR--WanrhtgynLDAYTKGRT------FVHVDIEPTQLG- 310
Cdd:PRK09259 250 AKGLLPDTHPQSAA------AAR--SLALANADVVLLVGARlnW--------LLSHGKGKTwgadkkFIQIDIEPQEIDs 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 311 --KIFAPDFG-IASDAKAALElfieiakELKAEGKLPDfSAWAASAQERK----GSLQRRTHFDDIPLKPQRVYEEMNKA 383
Cdd:PRK09259 314 nrPIAAPVVGdIGSVMQALLA-------GLKQNTFKAP-AEWLDALAERKeknaAKMAEKLSTDTQPMNFYNALGAIRDV 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 384 F--GPETrYVTTIGLSQIAAAQ-FLHVYRPRNWINCGQAGPLGWTIPAAIGAATaEPETPIVALSGDYDFQFMIEELAVA 460
Cdd:PRK09259 386 LkeNPDI-YLVNEGANTLDLARnIIDMYKPRHRLDCGTWGVMGIGMGYAIAAAV-ETGKPVVAIEGDSAFGFSGMEVETI 463
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2429932465 461 AQHKVPYVHVLVNNaylglirqaqGGLGINFEVNLEFENINTPELCVYGVDHVKVAEGLGVKAIRVTDPDKLGEAFEEA 539
Cdd:PRK09259 464 CRYNLPVTVVIFNN----------GGIYRGDDVNLSGAGDPSPTVLVHHARYDKMMEAFGGVGYNVTTPDELRHALTEA 532
|
|
| PRK06546 |
PRK06546 |
pyruvate dehydrogenase; Provisional |
4-568 |
6.67e-35 |
|
pyruvate dehydrogenase; Provisional
Pssm-ID: 180614 [Multi-domain] Cd Length: 578 Bit Score: 138.97 E-value: 6.67e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 4 MTAAAAAVEILKIEGVSQAFGVPGAAINPFYRELKNVGGIGHTLARHVEGASHMAEgytrAKA---GNIGVCIGTSGPAG 80
Cdd:PRK06546 3 KTVAEQLVEQLVAAGVKRIYGIVGDSLNPIVDAVRRTGGIEWVHVRHEEAAAFAAA----AEAqltGKLAVCAGSCGPGN 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 81 TDMITGLYSAIADSIPILCITGQAPVSKLHKEDFQAVDIASIAGPVTKKATTVLEAAQVPGVFQEAF-HLMrsGRPGPVL 159
Cdd:PRK06546 79 LHLINGLYDAHRSGAPVLAIASHIPSAQIGSGFFQETHPDRLFVECSGYCEMVSSAEQAPRVLHSAIqHAV--AGGGVSV 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 160 IDLPIDVQLTEIefdPETYAPLPVYKPRAT----RAQAAKALGFLLESQRPLIVAGGGIinADASDLLVEFAELVGVPVI 235
Cdd:PRK06546 157 VTLPGDIADEPA---PEGFAPSVISPRRPTvvpdPAEVRALADAINEAKKVTLFAGAGV--RGAHAEVLALAEKIKAPVG 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 236 STLMGWGTIPDDHQLAAGMVGVQTahrYGNAT--FLESDFVFGIGnrwanrhTGYNLDAYTKGRTFVHVDIEPTQLGKIF 313
Cdd:PRK06546 232 HSLRGKEWIQYDNPFDVGMSGLLG---YGAAHeaMHEADLLILLG-------TDFPYDQFLPDVRTAQVDIDPEHLGRRT 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 314 APDFGIASDAKAALELFIEIAKELKAEGKLPDFSAWAASAQERKGSLQRRTHFDDIPLKPQRVYEEMNKAFGPETRYVTT 393
Cdd:PRK06546 302 RVDLAVHGDVAETIRALLPLVKEKTDRRFLDRMLKKHARKLEKVVGAYTRKVEKHTPIHPEYVASILDELAADDAVFTVD 381
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 394 IGLSQIAAAQFLHVYRPRNWINCGQAGPLGWTIPAAIGAATAEPETPIVALSGDYDFQFMIEELAVAAQHKVPYVHVLVN 473
Cdd:PRK06546 382 TGMCNVWAARYITPNGRRRVIGSFRHGSMANALPHAIGAQLADPGRQVISMSGDGGLSMLLGELLTVKLYDLPVKVVVFN 461
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 474 NAYLGLirqaqgglginfeVNLEFENINTPElcvYGVDH-----VKVAEGLGVKAIRVTDPDKLGEAFEEAkkLAqeFQV 548
Cdd:PRK06546 462 NSTLGM-------------VKLEMLVDGLPD---FGTDHppvdyAAIAAALGIHAVRVEDPKDVRGALREA--FA--HPG 521
|
570 580 590
....*....|....*....|....*....|....*
gi 2429932465 549 PVVVEAILE--------RIT-------NIAMSKTV 568
Cdd:PRK06546 522 PALVDVVTDpnalsippTITgeqvkgfALAASKTV 556
|
|
| PRK08273 |
PRK08273 |
thiamine pyrophosphate protein; Provisional |
18-555 |
3.79e-34 |
|
thiamine pyrophosphate protein; Provisional
Pssm-ID: 181344 [Multi-domain] Cd Length: 597 Bit Score: 136.96 E-value: 3.79e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 18 GVSQAFGVPGAAINPFYRELKNVGG-IGHTLARHVEGASHMAEGYtrAK-AGNIGVCIGTSGPAGTDMITGLYSAIADSI 95
Cdd:PRK08273 17 GVRRVFGYPGDGINGLLGALGRADDkPEFVQARHEEMAAFMAVAH--AKfTGEVGVCLATSGPGAIHLLNGLYDAKLDHV 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 96 PILCITGQAPVSKLHKEDFQAVDIASIAGPVTKK-ATTVLEAAQVPGVFQEAFHLMRSGRpGPVLIDLPIDVQltEIEFD 174
Cdd:PRK08273 95 PVVAIVGQQARAALGGHYQQEVDLQSLFKDVAGAfVQMVTVPEQLRHLVDRAVRTALAER-TVTAVILPNDVQ--ELEYE 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 175 PETYA----------PLPVYKPRATRAQAAKALgfLLESQRPLIVAGGGIinADASDLLVEFAELVGVPVISTLMGWGTI 244
Cdd:PRK08273 172 PPPHAhgtvhsgvgyTRPRVVPYDEDLRRAAEV--LNAGRKVAILVGAGA--LGATDEVIAVAERLGAGVAKALLGKAAL 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 245 PDDHQL---AAGMVGVQTAHRYGNatflESDFVFGIGNRWAnrhtgYN--LDAYTKGRTfVHVDIEPTQLGKIFAPDFGI 319
Cdd:PRK08273 248 PDDLPWvtgSIGLLGTKPSYELMR----ECDTLLMVGSSFP-----YSefLPKEGQARG-VQIDIDGRMLGLRYPMEVNL 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 320 ASDAKAALELFIEIAKELKAEGKLPDFSAWAASAQErkgSLQRRTHFDDIPLKPQRVYEEMNKAFgPETRYVTtiGLSQI 399
Cdd:PRK08273 318 VGDAAETLRALLPLLERKKDRSWRERIEKWVARWWE---TLEARAMVPADPVNPQRVFWELSPRL-PDNAILT--ADSGS 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 400 AAAQFLHVYRPRNWINCGQAGPL---GWTIPAAIGAATAEPETPIVALSGDYDFQfM--IEELAVAAQH----KVPYVHV 470
Cdd:PRK08273 392 CANWYARDLRMRRGMMASLSGTLatmGPAVPYAIAAKFAHPDRPVIALVGDGAMQ-MngMAELITVAKYwrqwSDPRLIV 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 471 LV-NNAYLGLI---RQAQGGLGInFEvnlefENINTPElcvygVDHVKVAEGLGVKAIRVTDPDKLGEAFEEAkkLAQEf 546
Cdd:PRK08273 471 LVlNNRDLNQVtweQRVMEGDPK-FE-----ASQDLPD-----VPYARFAELLGLKGIRVDDPEQLGAAWDEA--LAAD- 536
|
....*....
gi 2429932465 547 qVPVVVEAI 555
Cdd:PRK08273 537 -RPVVLEVK 544
|
|
| PRK07092 |
PRK07092 |
benzoylformate decarboxylase; Reviewed |
1-557 |
9.78e-34 |
|
benzoylformate decarboxylase; Reviewed
Pssm-ID: 235931 [Multi-domain] Cd Length: 530 Bit Score: 135.08 E-value: 9.78e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 1 MPRMTAAAAAV--------EILKIEGVSQAFGVPGAAINPFYRELKNvgGIGHTLARHVEGASHMAEGYTRAkAGNIGVc 72
Cdd:PRK07092 1 MPKATAPAAAMttvrdatiDLLRRFGITTVFGNPGSTELPFLRDFPD--DFRYVLGLQEAVVVGMADGYAQA-TGNAAF- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 73 IGTSGPAGTDMITG-LYSAIADSIPILCITGQAPVSKLHKEDF-QAVDIASIAGPVTKKATTVLEAAQVPGVFQEAFHLM 150
Cdd:PRK07092 77 VNLHSAAGVGNAMGnLFTAFKNHTPLVITAGQQARSILPFEPFlAAVQAAELPKPYVKWSIEPARAEDVPAAIARAYHIA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 151 RSGRPGPVLIDLPIDvqlteiEFDPETyAPLPVYK-------PRATRAQAAKALGfllESQRPLIVAGGGIINADASDLL 223
Cdd:PRK07092 157 MQPPRGPVFVSIPYD------DWDQPA-EPLPARTvssavrpDPAALARLGDALD---AARRPALVVGPAVDRAGAWDDA 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 224 VEFAELVGVPV-ISTLMGWGTIPDDHQLAAGmvgVQTAHRYG-NATFLESDFVFGIG---NRWANRHTGYNLDAytkGRT 298
Cdd:PRK07092 227 VRLAERHRAPVwVAPMSGRCSFPEDHPLFAG---FLPASREKiSALLDGHDLVLVIGapvFTYHVEGPGPHLPE---GAE 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 299 FVHVDIEPtqLGKIFAPdFGIA--SDAKAALELFIEIAKELK--AEGKLPDFSAWAASAQerkgslqrrthfddiPLKPQ 374
Cdd:PRK07092 301 LVQLTDDP--GEAAWAP-MGDAivGDIRLALRDLLALLPPSArpAPPARPMPPPAPAPGE---------------PLSVA 362
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 375 RVYEEMNKAFGPETRYVTTIGLSQIAAAQFLHVYRPRNWINcGQAGPLGWTIPAAIGAATAEPETPIVALSGDYDFQFMI 454
Cdd:PRK07092 363 FVLQTLAALRPADAIVVEEAPSTRPAMQEHLPMRRQGSFYT-MASGGLGYGLPAAVGVALAQPGRRVIGLIGDGSAMYSI 441
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 455 EELAVAAQHKVPYVHVLVNNAYLGLIRQAQGGLGINfevnlefeniNTPELCVYGVDHVKVAEGLGVKAIRVTDPDKLGE 534
Cdd:PRK07092 442 QALWSAAQLKLPVTFVILNNGRYGALRWFAPVFGVR----------DVPGLDLPGLDFVALARGYGCEAVRVSDAAELAD 511
|
570 580
....*....|....*....|...
gi 2429932465 535 AFEEAkkLAQEfqVPVVVEAILE 557
Cdd:PRK07092 512 ALARA--LAAD--GPVLVEVEVA 530
|
|
| PDC1 |
COG3961 |
TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase [Carbohydrate ... |
11-558 |
1.12e-31 |
|
TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase [Carbohydrate transport and metabolism, Coenzyme transport and metabolism, General function prediction only]; TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase is part of the Pathway/BioSystem: Pyruvate oxidation
Pssm-ID: 443161 [Multi-domain] Cd Length: 545 Bit Score: 129.12 E-value: 1.12e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 11 VEILKIEGVSQAFGVPGAAINPFYRELKNVGGIghtlaRHV----E-GASHMAEGYTRAKaGnIGVCIGTSGPAGTDMIT 85
Cdd:COG3961 12 LDRLAELGIRHIFGVPGDYNLPFLDAIEAHPGI-----RWVgccnElNAGYAADGYARVN-G-LGALVTTYGVGELSAIN 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 86 GLYSAIADSIPILCITGqAPVSK-------LH----KEDFQAVdiASIAGPVTKkATTVLEA----AQVPGVFQEAFHLM 150
Cdd:COG3961 85 GIAGAYAERVPVVHIVG-APGTRaqrrgplLHhtlgDGDFDHF--LRMFEEVTV-AQAVLTPenaaAEIDRVLAAALREK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 151 RsgrpgPVLIDLPIDVQLTEIEfdpETYAPLPVYKPRATRAQAAKALG----FLLESQRPLIVAGGGIINADASDLLVEF 226
Cdd:COG3961 161 R-----PVYIELPRDVADAPIE---PPEAPLPLPPPASDPAALAAAVAaaaeRLAKAKRPVILAGVEVHRFGLQEELLAL 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 227 AELVGVPVISTLMGWGTIPDDHQLAAGMVGVQTAHRYGNATFLESDFVFGIGNRWanrhTGYNLDAYT----KGRTfvhV 302
Cdd:COG3961 233 AEKTGIPVATTLLGKSVLDESHPQFIGTYAGAASSPEVREYVENADCVLCLGVVF----TDTNTGGFTaqldPERT---I 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 303 DIEPTQL---GKIFAPdfgiasdakAALELFIEiakELKAegKLPDFSAWAASAQERKGSLQRRthfDDIPLKPQRVYEE 379
Cdd:COG3961 306 DIQPDSVrvgGHIYPG---------VSLADFLE---ALAE--LLKKRSAPLPAPAPPPPPPPAA---PDAPLTQDRLWQR 368
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 380 MNKAFGPETRYVTTIGLSQIAAAqFLHVYRPRNWINCGQAGPLGWTIPAAIGAATAEPETPIVALSGDYDFQFMIEELAV 459
Cdd:COG3961 369 LQAFLDPGDIVVADTGTSLFGAA-DLRLPEGATFIAQPLWGSIGYTLPAALGAALAAPDRRVILLVGDGAFQLTAQELST 447
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 460 AAQHKVPYVHVLVNNaylglirqaqGGLGInfEVNLEFENIntpelcVYGV----DHVKVAEGLG---VKAIRVTDPDKL 532
Cdd:COG3961 448 MLRYGLKPIIFVLNN----------DGYTI--ERAIHGPDG------PYNDianwDYAKLPEAFGggnALGFRVTTEGEL 509
|
570 580
....*....|....*....|....*.
gi 2429932465 533 GEAFEEAKKLAQEfqvPVVVEAILER 558
Cdd:COG3961 510 EEALAAAEANTDR---LTLIEVVLDK 532
|
|
| TPP_POX |
cd02014 |
Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; ... |
370-558 |
5.20e-31 |
|
Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates pyruvate, producing hydrogen peroxide and the energy-storage metabolite acetylphosphate. It requires FAD in addition to TPP and a divalent cation as cofactors.
Pssm-ID: 238972 [Multi-domain] Cd Length: 178 Bit Score: 118.79 E-value: 5.20e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 370 PLKPQRVYEEMNKAFGPETRYVTTIGLSQIAAAQFLHVYRPRNWINCGQAGPLGWTIPAAIGAATAEPETPIVALSGDYD 449
Cdd:cd02014 1 PIHPERVAAELNKRAPDDAIFTIDVGNVTVWAARHLRMNGKQRFILSGLLATMGNGLPGAIAAKLAYPDRQVIALSGDGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 450 FQFMIEELAVAAQHKVPYVHVLVNNAYLGLIR--QAQGGLgINFEVNLefenintpelcvYGVDHVKVAEGLGVKAIRVT 527
Cdd:cd02014 81 FAMLMGDLITAVKYNLPVIVVVFNNSDLGFIKweQEVMGQ-PEFGVDL------------PNPDFAKIAEAMGIKGIRVE 147
|
170 180 190
....*....|....*....|....*....|.
gi 2429932465 528 DPDKLGEAFEEAKKLaqefQVPVVVEAILER 558
Cdd:cd02014 148 DPDELEAALDEALAA----DGPVVIDVVTDP 174
|
|
| TPP_PYR_POX |
cd07039 |
Pyrimidine (PYR) binding domain of POX; Thiamine pyrophosphate (TPP family), pyrimidine (PYR) ... |
5-167 |
8.10e-29 |
|
Pyrimidine (PYR) binding domain of POX; Thiamine pyrophosphate (TPP family), pyrimidine (PYR) binding domain of pyruvate oxidase (POX) subfamily. The PYR domain is found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. TPP binds in the cleft formed by a PYR domain and a PP domain. The PYR domain, binds the aminopyrimidine ring of TPP, the PP domain binds the diphosphate residue. The PYR and PP domains have a common fold, but do not share strong sequence conservation. The PP domain is not included in this sub-family. Most TPP-dependent enzymes have the PYR and PP domains on the same subunit although these domains can be alternatively arranged in the primary structure. TPP-dependent enzymes are multisubunit proteins, the smallest catalytic unit being a dimer-of-active sites. Lactobacillus plantarum POX is a homotetramer (dimer-of-homodimers), having two active sites per homodimer lying between PYR and PP domains of different subunits. POX decarboxylates pyruvate, producing hydrogen peroxide and the energy-storage metabolite acetylphosphate.
Pssm-ID: 132922 [Multi-domain] Cd Length: 164 Bit Score: 112.26 E-value: 8.10e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 5 TAAAAAVEILKIEGVSQAFGVPGAAINPFYRELKNVGGIGHTLARHVEGASHMAEGYtrAK-AGNIGVCIGTSGPAGTDM 83
Cdd:cd07039 1 TVADVIVETLENWGVKRVYGIPGDSINGLMDALRREGKIEFIQVRHEEAAAFAASAE--AKlTGKLGVCLGSSGPGAIHL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 84 ITGLYSAIADSIPILCITGQAPVSKLHKEDFQAVDIASIAGPVTKKATTVLEAAQVPGVFQEAfhlMRS--GRPGPVLID 161
Cdd:cd07039 79 LNGLYDAKRDRAPVLAIAGQVPTDELGTDYFQEVDLLALFKDVAVYNETVTSPEQLPELLDRA---IRTaiAKRGVAVLI 155
|
....*.
gi 2429932465 162 LPIDVQ 167
Cdd:cd07039 156 LPGDVQ 161
|
|
| TPP_Xsc_like |
cd02013 |
Thiamine pyrophosphate (TPP) family, Xsc-like subfamily, TPP-binding module; composed of ... |
370-558 |
8.53e-22 |
|
Thiamine pyrophosphate (TPP) family, Xsc-like subfamily, TPP-binding module; composed of proteins similar to Alcaligenes defragrans sulfoacetaldehyde acetyltransferase (Xsc). Xsc plays a key role in the degradation of taurine, catalyzing the desulfonation of 2-sulfoacetaldehyde into sulfite and acetyl phosphate. This enzyme requires TPP and divalent metal ions for activity.
Pssm-ID: 238971 [Multi-domain] Cd Length: 196 Bit Score: 93.34 E-value: 8.53e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 370 PLKPQRVYEEMNKAFgPETRYVTT-IGLSQIAAAQFLHVYRPRNWINCGQAGPLGWTIPAAIGAATAEPETPIVALSGDY 448
Cdd:cd02013 3 PMHPRQVLRELEKAM-PEDAIVSTdIGNICSVANSYLRFEKPRSFIAPLSFGNCGYALPAIIGAKAAAPDRPVVAIAGDG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 449 DFQFMIEELAVAAQHKVPYVHVLVNNAYLGLIRQAQGGLGINFEVNLEFENINtpelcvygvdHVKVAEGLGVKAIRVTD 528
Cdd:cd02013 82 AWGMSMMEIMTAVRHKLPVTAVVFRNRQWGAEKKNQVDFYNNRFVGTELESES----------FAKIAEACGAKGITVDK 151
|
170 180 190
....*....|....*....|....*....|
gi 2429932465 529 PDKLGEAFEEAKKLAQEFQvPVVVEAILER 558
Cdd:cd02013 152 PEDVGPALQKAIAMMAEGK-TTVIEIVCDQ 180
|
|
| TPP_enzyme_PYR |
cd06586 |
Pyrimidine (PYR) binding domain of thiamine pyrophosphate (TPP)-dependent enzymes; Thiamine ... |
8-163 |
2.02e-21 |
|
Pyrimidine (PYR) binding domain of thiamine pyrophosphate (TPP)-dependent enzymes; Thiamine pyrophosphate (TPP) family, pyrimidine (PYR) binding domain; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. TPP binds in the cleft formed by a PYR domain and a PP domain. The PYR domain, binds the aminopyrimidine ring of TPP, the PP domain binds the diphosphate residue. A polar interaction between the conserved glutamate of the PYR domain and the N1' of the TPP aminopyrimidine ring is shared by most TPP-dependent enzymes, and participates in the activation of TPP. The PYR and PP domains have a common fold, but do not share strong sequence conservation. The PP domain is not included in this group. Most TPP-dependent enzymes have the PYR and PP domains on the same subunit although these domains can be alternatively arranged in the primary structure. In the case of 2-oxoisovalerate dehydrogenase (2OXO), sulfopyruvate decarboxylase (ComDE), and the E1 component of human pyruvate dehydrogenase complex (E1- PDHc) the PYR and PP domains appear on different subunits. TPP-dependent enzymes are multisubunit proteins, the smallest catalytic unit being a dimer-of-active sites. For many of these enzymes the active sites lie between PP and PYR domains on different subunits. However, for the homodimeric enzymes 1-deoxy-D-xylulose 5-phosphate synthase (DXS) and Desulfovibrio africanus pyruvate:ferredoxin oxidoreductase (PFOR), each active site lies at the interface of the PYR and PP domains from the same subunit.
Pssm-ID: 132915 [Multi-domain] Cd Length: 154 Bit Score: 90.87 E-value: 2.02e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 8 AAAVEILKIEGVSQAFGVPGAAINPFYRELKNVGGIGHTLARHVEGASHMAEGYtrAKAGNIGVCIGTSGPAGTDMITGL 87
Cdd:cd06586 1 AAFAEVLTAWGVRHVFGYPGDEISSLLDALREGDKRIIDTVIHELGAAGAAAGY--ARAGGPPVVIVTSGTGLLNAINGL 78
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2429932465 88 YSAIADSIPILCITGQAPVSKLHKEDFQAVDIASIAGPVTKKATTVLEAAQVPGVFQEAFHLMRSGrPGPVLIDLP 163
Cdd:cd06586 79 ADAAAEHLPVVFLIGARGISAQAKQTFQSMFDLGMYRSIPEANISSPSPAELPAGIDHAIRTAYAS-QGPVVVRLP 153
|
|
| TPP_BFDC |
cd02002 |
Thiamine pyrophosphate (TPP) family, BFDC subfamily, TPP-binding module; composed of proteins ... |
373-556 |
4.95e-20 |
|
Thiamine pyrophosphate (TPP) family, BFDC subfamily, TPP-binding module; composed of proteins similar to Pseudomonas putida benzoylformate decarboxylase (BFDC). P. putida BFDC plays a role in the mandelate pathway, catalyzing the conversion of benzoylformate to benzaldehyde and carbon dioxide. This enzyme is dependent on TPP and a divalent metal cation as cofactors.
Pssm-ID: 238960 [Multi-domain] Cd Length: 178 Bit Score: 87.65 E-value: 4.95e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 373 PQRVYEEMNKAFGPETRYVTTIGLSQIAAAQFLHVYRPRNWINCGqAGPLGWTIPAAIGAATAEPETPIVALSGDYDFQF 452
Cdd:cd02002 3 PEYLAAALAAALPEDAIIVDEAVTNGLPLRDQLPLTRPGSYFTLR-GGGLGWGLPAAVGAALANPDRKVVAIIGDGSFMY 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 453 MIEELAVAAQHKVP-YVHVLVNNAYLGL----IRQAQGGLGINFEVNLEFENintPELcvygvDHVKVAEGLGVKAIRVT 527
Cdd:cd02002 82 TIQALWTAARYGLPvTVVILNNRGYGALrsflKRVGPEGPGENAPDGLDLLD---PGI-----DFAAIAKAFGVEAERVE 153
|
170 180
....*....|....*....|....*....
gi 2429932465 528 DPDKLGEAFEEAKklaqEFQVPVVVEAIL 556
Cdd:cd02002 154 TPEELDEALREAL----AEGGPALIEVVV 178
|
|
| TPP_BZL_OCoD_HPCL |
cd02004 |
Thiamine pyrophosphate (TPP) family, BZL_OCoD_HPCL subfamily, TPP-binding module; composed of ... |
373-557 |
6.62e-20 |
|
Thiamine pyrophosphate (TPP) family, BZL_OCoD_HPCL subfamily, TPP-binding module; composed of proteins similar to benzaldehyde lyase (BZL), oxalyl-CoA decarboxylase (OCoD) and 2-hydroxyphytanoyl-CoA lyase (2-HPCL). Pseudomonas fluorescens biovar I BZL cleaves the acyloin linkage of benzoin producing 2 molecules of benzaldehyde and enabling the Pseudomonas to grow on benzoin as the sole carbon and energy source. OCoD has a role in the detoxification of oxalate, catalyzing the decarboxylation of oxalyl-CoA to formate. 2-HPCL is a peroxisomal enzyme which plays a role in the alpha-oxidation of 3-methyl-branched fatty acids, catalyzing the cleavage of 2-hydroxy-3-methylacyl-CoA into formyl-CoA and a 2-methyl-branched fatty aldehyde. All these enzymes depend on Mg2+ and TPP for activity.
Pssm-ID: 238962 [Multi-domain] Cd Length: 172 Bit Score: 87.20 E-value: 6.62e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 373 PQRVYEEMNKAFGPETRYVTTIGLSQIAAAQFLHVYRPRNWINCGQAGPLGWTIPAAIGAATAEPETPIVALSGDYDFQF 452
Cdd:cd02004 1 PYRVLHELQEALPDDAIIVSDGGNTMDWARYILRPRKPRHRLDAGTFGTLGVGLGYAIAAALARPDKRVVLVEGDGAFGF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 453 MIEELAVAAQHKVPYVHVLVNNaylglirqaqGGLGINFEVNLEFENINTPELC-VYGVDHVKVAEGLGVKAIRVTDPDK 531
Cdd:cd02004 81 SGMELETAVRYNLPIVVVVGNN----------GGWYQGLDGQQLSYGLGLPVTTlLPDTRYDLVAEAFGGKGELVTTPEE 150
|
170 180
....*....|....*....|....*.
gi 2429932465 532 LGEAFEEAKKLAQefqvPVVVEAILE 557
Cdd:cd02004 151 LKPALKRALASGK----PALINVIID 172
|
|
| TPP_ALS |
cd02010 |
Thiamine pyrophosphate (TPP) family, Acetolactate synthase (ALS) subfamily, TPP-binding module; ... |
373-553 |
5.61e-19 |
|
Thiamine pyrophosphate (TPP) family, Acetolactate synthase (ALS) subfamily, TPP-binding module; composed of proteins similar to Klebsiella pneumoniae ALS, a catabolic enzyme required for butanediol fermentation. ALS catalyzes the conversion of 2 molecules of pyruvate to acetolactate and carbon dioxide. ALS does not contain FAD, and requires TPP and a divalent metal cation for activity.
Pssm-ID: 238968 [Multi-domain] Cd Length: 177 Bit Score: 84.65 E-value: 5.61e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 373 PQRVYEEMNKAFGPETRYVTTIGLSQIAAAQFLHVYRPRN-WINCGQAgPLGWTIPAAIGAATAEPETPIVALSGDYDFQ 451
Cdd:cd02010 1 PQRIVHDLRAVMGDDDIVLLDVGAHKIWMARYYRTYAPNTcLISNGLA-TMGVALPGAIGAKLVYPDRKVVAVSGDGGFM 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 452 FMIEELAVAAQHKVPYVH-VLVNNAYlGLIR-QAQGGLGINFEVnlEFENIntpelcvygvDHVKVAEGLGVKAIRVTDP 529
Cdd:cd02010 80 MNSQELETAVRLKIPLVVlIWNDNGY-GLIKwKQEKEYGRDSGV--DFGNP----------DFVKYAESFGAKGYRIESA 146
|
170 180
....*....|....*....|....
gi 2429932465 530 DKLGEAFEEAkkLAQEfqVPVVVE 553
Cdd:cd02010 147 DDLLPVLERA--LAAD--GVHVID 166
|
|
| TPP_IolD |
cd02003 |
Thiamine pyrophosphate (TPP) family, IolD subfamily, TPP-binding module; composed of proteins ... |
422-541 |
4.76e-16 |
|
Thiamine pyrophosphate (TPP) family, IolD subfamily, TPP-binding module; composed of proteins similar to Rhizobium leguminosarum bv. viciae IolD. IolD plays an important role in myo-inositol catabolism.
Pssm-ID: 238961 [Multi-domain] Cd Length: 205 Bit Score: 76.96 E-value: 4.76e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 422 LGWTIPAAIGAATAEPETPIVALSGDYDFQFMIEELAVAAQHKVPYVHVLVNNAYLGLIRQAQGGLGI-NFevNLEFENI 500
Cdd:cd02003 50 MGYEIAAGLGAKLAKPDREVYVLVGDGSYLMLHSEIVTAVQEGLKIIIVLFDNHGFGCINNLQESTGSgSF--GTEFRDR 127
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 2429932465 501 NTPELCVYG----VDHVKVAEGLGVKAIRVTDPDKLGEAFEEAKK 541
Cdd:cd02003 128 DQESGQLDGallpVDFAANARSLGARVEKVKTIEELKAALAKAKA 172
|
|
| TPP_PDC_IPDC |
cd02005 |
Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of ... |
370-558 |
9.10e-10 |
|
Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of pyruvate to acetaldehyde and CO2. It is able to utilize other 2-oxo acids as substrates. In plants and various plant-associated bacteria, IPDC plays a role in the indole-3-pyruvic acid (IPA) pathway, a tryptophan-dependent biosynthetic route to indole-3-acetaldehyde (IAA). IPDC catalyzes the decarboxylation of IPA to IAA. Both PDC and IPDC depend on TPP and Mg2+ as cofactors.
Pssm-ID: 238963 [Multi-domain] Cd Length: 183 Bit Score: 58.31 E-value: 9.10e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 370 PLKPQRVYEEMNKAFGPETRYVTTIGLSQIAAAQFLHvyrPRN--WINCGQAGPLGWTIPAAIGAATAEPETPIVALSGD 447
Cdd:cd02005 1 PLTQARLWQQVQNFLKPNDILVAETGTSWFGALDLKL---PKGtrFISQPLWGSIGYSVPAALGAALAAPDRRVILLVGD 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 448 YDFQFMIEELAVAAQHKVPYVHVLVNNAYLGLIRQAQGGlginfevNLEFENINTpelcvygVDHVKVAEGLG----VKA 523
Cdd:cd02005 78 GSFQMTVQELSTMIRYGLNPIIFLINNDGYTIERAIHGP-------EASYNDIAN-------WNYTKLPEVFGggggGLS 143
|
170 180 190
....*....|....*....|....*....|....*
gi 2429932465 524 IRVTDPDKLGEAFEEAKKLAqefQVPVVVEAILER 558
Cdd:cd02005 144 FRVKTEGELDEALKDALFNR---DKLSLIEVILPK 175
|
|
| PRK12474 |
PRK12474 |
hypothetical protein; Provisional |
1-556 |
1.16e-09 |
|
hypothetical protein; Provisional
Pssm-ID: 139002 [Multi-domain] Cd Length: 518 Bit Score: 61.04 E-value: 1.16e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 1 MPRMTAAAAAVEILKIEGVSQAFGVPGAAINPFYRELKNVGGIGHTLARHVEGASHMAEGYTRAkAGNIGVCIGTSGPAG 80
Cdd:PRK12474 2 GQTMNGADSVVDTLLNCGVEVCFANPGTSEMHFVAALDRVPRMRPVLCLFEGVVTGAADGYGRI-AGKPAVTLLHLGPGL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 81 TDMITGLYSAIADSIPILCITGQAPVSKLHKEDFQAVDIASIAGPVTKKATTVLEAAQVPGVFQEAFHLMRSGRPGPVLI 160
Cdd:PRK12474 81 ANGLANLHNARRAASPIVNIVGDHAVEHLQYDAPLTSDIDGFARPVSRWVHRSASAGAVDSDVARAVQAAQSAPGGIATL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 161 DLPIDVQLTEIEFdpeTYAPLPVYKPRATRAQAAKALGFLLESQRP--LIVAGGGIINADasdllVEFAELVGVPVISTL 238
Cdd:PRK12474 161 IMPADVAWNEAAY---AAQPLRGIGPAPVAAETVERIAALLRNGKKsaLLLRGSALRGAP-----LEAAGRIQAKTGVRL 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 239 MGWGTIPDDhQLAAGMVGV---QTAHRYGNATFLESDFVFGIGNRWANRHTGY-NLDAY--TKGRTFVHVdIEPTQLGKI 312
Cdd:PRK12474 233 YCDTFAPRI-ERGAGRVPIeriPYFHEQITAFLKDVEQLVLVGAKPPVSFFAYpGKPSWgaPPGCEIVYL-AQPDEDLAQ 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 313 FAPDFGIASDAKAALELFIEIAKELKAEGKLPDFSAWAASAQErkgslqrrthfddipLKPQRVY-EEMNKAFGPetryv 391
Cdd:PRK12474 311 ALQDLADAVDAPAEPAARTPLALPALPKGALNSLGVAQLIAHR---------------TPDQAIYaDEALTSGLF----- 370
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 392 ttigLSQIAAAQFLHVYRPRNwincgqAGPLGWTIPAAIGAATAEPETPIVALSGDYDFQFMIEELAVAAQHKVPYVHVL 471
Cdd:PRK12474 371 ----FDMSYDRARPHTHLPLT------GGSIGQGLPLAAGAAVAAPDRKVVCPQGDGGAAYTMQALWTMARENLDVTVVI 440
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 472 VNN---AYLG--LIRQAQGGLGINFEVNLEFENintPELcvygvDHVKVAEGLGVKAIRVTDPDKLGEAFEEAkkLAQef 546
Cdd:PRK12474 441 FANrsyAILNgeLQRVGAQGAGRNALSMLDLHN---PEL-----NWMKIAEGLGVEASRATTAEEFSAQYAAA--MAQ-- 508
|
570
....*....|
gi 2429932465 547 QVPVVVEAIL 556
Cdd:PRK12474 509 RGPRLIEAMI 518
|
|
| PRK07586 |
PRK07586 |
acetolactate synthase large subunit; |
409-539 |
3.11e-09 |
|
acetolactate synthase large subunit;
Pssm-ID: 236063 [Multi-domain] Cd Length: 514 Bit Score: 59.47 E-value: 3.11e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 409 RPRNWI-NCGqaGPLGWTIPAAIGAATAEPETPIVALSGDYDFQFMIEELAVAAQHKVPYVHVLVNN-AYLGL-IRQAQG 485
Cdd:PRK07586 375 APHDWLtLTG--GAIGQGLPLATGAAVACPDRKVLALQGDGSAMYTIQALWTQARENLDVTTVIFANrAYAILrGELARV 452
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 2429932465 486 GLGINFEVNLEFENINTPELcvygvDHVKVAEGLGVKAIRVTDPDKLGEAFEEA 539
Cdd:PRK07586 453 GAGNPGPRALDMLDLDDPDL-----DWVALAEGMGVPARRVTTAEEFADALAAA 501
|
|
| TPP_IOR_alpha |
cd02008 |
Thiamine pyrophosphate (TPP) family, IOR-alpha subfamily, TPP-binding module; composed of ... |
373-552 |
1.37e-05 |
|
Thiamine pyrophosphate (TPP) family, IOR-alpha subfamily, TPP-binding module; composed of proteins similar to indolepyruvate ferredoxin oxidoreductase (IOR) alpha subunit. IOR catalyzes the oxidative decarboxylation of arylpyruvates, such as indolepyruvate or phenylpyruvate, which are generated by the transamination of aromatic amino acids, to the corresponding aryl acetyl-CoA.
Pssm-ID: 238966 [Multi-domain] Cd Length: 178 Bit Score: 45.73 E-value: 1.37e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 373 PQR-VYEEMNKAFGPETRYVTTIGLSQIAAAQflhvyrPRNWIN-CGQagpLGWTIPAAIGAATAEPETPIVALSGDYDF 450
Cdd:cd02008 11 PHRpSFYALRKAFKKDSIVSGDIGCYTLGALP------PLNAIDtCTC---MGASIGVAIGMAKASEDKKVVAVIGDSTF 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 451 QFM-IEELAVAAQHKVPYVHVLVNNAYLGLI-RQAQGGLGINfevNLEFENIntpelcvygVDHVKVAEGLGVKAIRVTD 528
Cdd:cd02008 82 FHSgILGLINAVYNKANITVVILDNRTTAMTgGQPHPGTGKT---LTEPTTV---------IDIEALVRAIGVKRVVVVD 149
|
170 180
....*....|....*....|....
gi 2429932465 529 PDKLGEAFEEAKKLAQEFQVPVVV 552
Cdd:cd02008 150 PYDLKAIREELKEALAVPGVSVII 173
|
|
| TPP_PYR_PDC_IPDC_like |
cd07038 |
Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase ... |
11-164 |
1.79e-05 |
|
Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Thiamine pyrophosphate (TPP family), pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC) subfamily. The PYR domain is found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. TPP binds in the cleft formed by a PYR domain and a PP domain. The PYR domain, binds the aminopyrimidine ring of TPP, the PP domain binds the diphosphate residue. The PYR and PP domains have a common fold, but do not share strong sequence conservation. The PP domain is not included in this sub-family. Most TPP-dependent enzymes have the PYR and PP domains on the same subunit although these domains can be alternatively arranged in the primary structure. TPP-dependent enzymes are multisubunit proteins, the smallest catalytic unit being a dimer-of-active sites, for many the active sites lie between PP and PYR domains on different subunits. PDC catalyzes the conversion of pyruvate to acetaldehyde and CO2 in alcoholic fermentation. IPDC plays a role in the indole-3-pyruvic acid (IPA) pathway in plants and various plant-associated bacteria, it catalyzes the decarboxylation of IPA to IAA. Also belonging to this group is Mycobacterium tuberculosis alpha-keto acid decarboxylase (MtKDC) which participates in amino acid degradation via the Ehrlich pathway, and Lactococcus lactis branched-chain keto acid decarboxylase (KdcA) an enzyme identified as being involved in cheese ripening, which exhibits a very broad substrate range in the decarboxylation and carboligation reactions.
Pssm-ID: 132921 [Multi-domain] Cd Length: 162 Bit Score: 45.18 E-value: 1.79e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 11 VEILKIEGVSQAFGVPGAAINPFYRELKNVGGIghtlaRHVE-----GASHMAEGYTRAKAgnIGVCIGTSGPAGTDMIT 85
Cdd:cd07038 4 LERLKQLGVKHVFGVPGDYNLPLLDAIEENPGL-----RWVGncnelNAGYAADGYARVKG--LGALVTTYGVGELSALN 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 86 GLYSAIADSIPILCITGQAPVS----------KLHKEDFQAvdIASIAGPVTkKATTVLE-----AAQVPGVFQEAFHLM 150
Cdd:cd07038 77 GIAGAYAEHVPVVHIVGAPSTKaqasglllhhTLGDGDFDV--FLKMFEEIT-CAAARLTdpenaAEEIDRVLRTALRES 153
|
170
....*....|....
gi 2429932465 151 RsgrpgPVLIDLPI 164
Cdd:cd07038 154 R-----PVYIEIPR 162
|
|
| TPP_PYR_MenD |
cd07037 |
Pyrimidine (PYR) binding domain of ... |
8-164 |
1.36e-04 |
|
Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1-carboxylate synthase (MenD) and related proteins; Thiamine pyrophosphate (TPP family), pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1-carboxylate (SEPHCHC) synthase (MenD) subfamily. The PYR domain is found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. TPP binds in the cleft formed by a PYR domain and a PP domain. The PYR domain, binds the aminopyrimidine ring of TPP, the PP domain binds the diphosphate residue. The PYR and PP domains have a common fold, but do not share strong sequence conservation. The PP domain is not included in this sub-family. Most TPP-dependent enzymes have the PYR and PP domains on the same subunit although these domains can be alternatively arranged in the primary structure. TPP-dependent enzymes are multisubunit proteins, the smallest catalytic unit being a dimer-of-active sites. Escherichia coli MenD (EcMenD) is a homotetramer (dimer-of-homodimers), having two active sites per homodimer lying between PYR and PP domains of different subunits. EcMenD catalyzes a Stetter-like conjugate addition of alpha-ketoglutarate to isochorismate, leading to the formation of SEPHCHC and carbon dioxide, this addition is the first committed step in the biosynthesis of vitamin K2 (menaquinone).
Pssm-ID: 132920 [Multi-domain] Cd Length: 162 Bit Score: 42.49 E-value: 1.36e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 8 AAAVEILKIEGVSQAFGVPGAAINPFYRELKNVGGIghTLARHVE--GASHMAEGYTRAkAGNIGVCIGTSGPAGTDmit 85
Cdd:cd07037 1 QALVEELKRLGVRDVVISPGSRSAPLALAAAEHPEF--RLHVRVDerSAAFFALGLAKA-SGRPVAVVCTSGTAVAN--- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2429932465 86 gLYSAIA----DSIPILCITGQAPVSKLHKEDFQAVDIASIAGPVTKKATTV------LEAAQVPGVFQEAFHLMRSGRP 155
Cdd:cd07037 75 -LLPAVVeayySGVPLLVLTADRPPELRGTGANQTIDQVGLFGDYVRWSVDLpppeddDDLWYLLRLANRAVLEALSAPP 153
|
....*....
gi 2429932465 156 GPVLIDLPI 164
Cdd:cd07037 154 GPVHLNLPF 162
|
|
| |
