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Conserved domains on  [gi|1795718394|emb|VTP05558|]
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Alpha-D-kanosaminyltransferase [Mycobacterium kansasii]

Protein Classification

GT2 and GT4_PimA-like domain-containing protein( domain architecture ID 11440408)

GT2 and GT4_PimA-like domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GT4_PimA-like cd03801
phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 ...
 331-667 4.31e-45

phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.


:

Pssm-ID: 340831 [Multi-domain]  Cd Length: 366  Bit Score: 165.02  E-value: 4.31e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 331 IVIVTNRL--VYGGAERQKALLATELDRRGYPVTIVCVQRFGPLINEIPHSVRVVRQPWWAPIVDIPA------GPAVLI 402
Cdd:cd03801     2 ILLLSPELppPVGGAERHVRELARALAARGHDVTVLTPADPGEPPEELEDGVIVPLLPSLAALLRARRllrelrPLLRLR 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 403 SGD----TNTETGFATLWRAAAKSRRWLVAAHIPPEDNRPIYSRPLTAAMRRADGFIVLAQRH--------WEMLTAHHR 470
Cdd:cd03801    82 KFDvvhaHGLLAALLAALLALLLGAPLVVTLHGAEPGRLLLLLAAERRLLARAEALLRRADAViavsealrDELRALGGI 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 471 LGGRRFVAPNGVAAAGDPAPPIRGVGQPPH---LVMLSRIVEHKNPHLLVEALAGLTEMR--WRLSIFG-DGPDRERLQA 544
Cdd:cd03801   162 PPEKIVVIPNGVDLERFSPPLRRKLGIPPDrpvLLFVGRLSPRKGVDLLLEALAKLLRRGpdVRLVIVGgDGPLRAELEE 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 545 RTpAELRDRVQWRGWSAGP--GPALADADLLCVPSRSEAFPLVILEAMAWAVPVAASAVCAVPEMLDFGRAGFVVEPVSV 622
Cdd:cd03801   242 LE-LGLGDRVRFLGFVPDEelPALYAAADVFVLPSRYEGFGLVVLEAMAAGLPVVATDVGGLPEVVEDGEGGLVVPPDDV 320

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*
gi 1795718394 623 SGWREQLAKILADPAALPSVGRRGFERMQQHYTVAAMADAYLDAI 667
Cdd:cd03801   321 EALADALLRLLADPELRARLGRAARERVAERFSWERVAERLLDLY 365
WcaE COG1216
Glycosyltransferase, GT2 family [Carbohydrate transport and metabolism];
25-276 3.60e-19

Glycosyltransferase, GT2 family [Carbohydrate transport and metabolism];


:

Pssm-ID: 440829 [Multi-domain]  Cd Length: 202  Bit Score: 86.20  E-value: 3.60e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394  25 SLAVLIVSCKNHDGLQTCLHSVAEH-LPKLPVYVYDSrgGGRPGREELVA--RHPAVHWVSGPVSRGFAAAFNTLVTHAP 101
Cdd:COG1216     4 KVSVVIPTYNRPELLRRCLESLLAQtYPPFEVIVVDN--GSTDGTAELLAalAFPRVRVIRNPENLGFAAARNLGLRAAG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 102 SDtDLLLLHADARVRgpltrtrellrrpwvaavspmvcddtapgrPPWdiaarrqtlIRALVAAAgysdslrgmpispry 181
Cdd:COG1216    82 GD-YLLFLDDDTVVE------------------------------PDW---------LERLLAAA--------------- 106

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 182 arqppesqsiegclgatCLAISRTAWNAIGGFDEEFFRYGEAADWQNRARAAGWRILLADEVgadrgnRVTgadaHVTGS 261
Cdd:COG1216   107 -----------------CLLIRREVFEEVGGFDERFFLYGEDVDLCLRLRKAGYRIVYVPDA------VVY----HLGGA 159

                         250
                  ....*....|....*
gi 1795718394 262 THEGAVAAAQHDRNR 276
Cdd:COG1216   160 SSGPLLRAYYLGRNR 174
 
Name Accession Description Interval E-value
GT4_PimA-like cd03801
phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 ...
 331-667 4.31e-45

phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.


Pssm-ID: 340831 [Multi-domain]  Cd Length: 366  Bit Score: 165.02  E-value: 4.31e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 331 IVIVTNRL--VYGGAERQKALLATELDRRGYPVTIVCVQRFGPLINEIPHSVRVVRQPWWAPIVDIPA------GPAVLI 402
Cdd:cd03801     2 ILLLSPELppPVGGAERHVRELARALAARGHDVTVLTPADPGEPPEELEDGVIVPLLPSLAALLRARRllrelrPLLRLR 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 403 SGD----TNTETGFATLWRAAAKSRRWLVAAHIPPEDNRPIYSRPLTAAMRRADGFIVLAQRH--------WEMLTAHHR 470
Cdd:cd03801    82 KFDvvhaHGLLAALLAALLALLLGAPLVVTLHGAEPGRLLLLLAAERRLLARAEALLRRADAViavsealrDELRALGGI 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 471 LGGRRFVAPNGVAAAGDPAPPIRGVGQPPH---LVMLSRIVEHKNPHLLVEALAGLTEMR--WRLSIFG-DGPDRERLQA 544
Cdd:cd03801   162 PPEKIVVIPNGVDLERFSPPLRRKLGIPPDrpvLLFVGRLSPRKGVDLLLEALAKLLRRGpdVRLVIVGgDGPLRAELEE 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 545 RTpAELRDRVQWRGWSAGP--GPALADADLLCVPSRSEAFPLVILEAMAWAVPVAASAVCAVPEMLDFGRAGFVVEPVSV 622
Cdd:cd03801   242 LE-LGLGDRVRFLGFVPDEelPALYAAADVFVLPSRYEGFGLVVLEAMAAGLPVVATDVGGLPEVVEDGEGGLVVPPDDV 320

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*
gi 1795718394 623 SGWREQLAKILADPAALPSVGRRGFERMQQHYTVAAMADAYLDAI 667
Cdd:cd03801   321 EALADALLRLLADPELRARLGRAARERVAERFSWERVAERLLDLY 365
Glyco_trans_1_4 pfam13692
Glycosyl transferases group 1;
498-635 6.94e-29

Glycosyl transferases group 1;


Pssm-ID: 463957 [Multi-domain]  Cd Length: 138  Bit Score: 111.83  E-value: 6.94e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 498 PPHLVMLSRIVE-HKNPHLLVEALAGL--TEMRWRLSIFGDGPDRErLQARTpAELRDRVQWRGWSAGPGPALADADLLC 574
Cdd:pfam13692   1 RPVILFVGRLHPnVKGVDYLLEAVPLLrkRDNDVRLVIVGDGPEEE-LEELA-AGLEDRVIFTGFVEDLAELLAAADVFV 78

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1795718394 575 VPSRSEAFPLVILEAMAWAVPVAASAVCAVPEMLDfGRAGFVVEPVSVSGWREQLAKILAD 635
Cdd:pfam13692  79 LPSLYEGFGLKLLEAMAAGLPVVATDVGGIPELVD-GENGLLVPPGDPEALAEAILRLLED 138
RfaB COG0438
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ...
 566-671 8.06e-26

Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440207 [Multi-domain]  Cd Length: 123  Bit Score: 102.76  E-value: 8.06e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 566 ALADADLLCVPSRSEAFPLVILEAMAWAVPVAASAVCAVPEMLDFGRAGFVVEPVSVSGWREQLAKILADPAALPSVGRR 645
Cdd:COG0438    17 LLAAADVFVLPSRSEGFGLVLLEAMAAGLPVIATDVGGLPEVIEDGETGLLVPPGDPEALAEAILRLLEDPELRRRLGEA 96

                          90       100
                  ....*....|....*....|....*.
gi 1795718394 646 GFERMQQHYTVAAMADAYLDAIDAVL 671
Cdd:COG0438    97 ARERAEERFSWEAIAERLLALYEELL 122
WcaE COG1216
Glycosyltransferase, GT2 family [Carbohydrate transport and metabolism];
25-276 3.60e-19

Glycosyltransferase, GT2 family [Carbohydrate transport and metabolism];


Pssm-ID: 440829 [Multi-domain]  Cd Length: 202  Bit Score: 86.20  E-value: 3.60e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394  25 SLAVLIVSCKNHDGLQTCLHSVAEH-LPKLPVYVYDSrgGGRPGREELVA--RHPAVHWVSGPVSRGFAAAFNTLVTHAP 101
Cdd:COG1216     4 KVSVVIPTYNRPELLRRCLESLLAQtYPPFEVIVVDN--GSTDGTAELLAalAFPRVRVIRNPENLGFAAARNLGLRAAG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 102 SDtDLLLLHADARVRgpltrtrellrrpwvaavspmvcddtapgrPPWdiaarrqtlIRALVAAAgysdslrgmpispry 181
Cdd:COG1216    82 GD-YLLFLDDDTVVE------------------------------PDW---------LERLLAAA--------------- 106

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 182 arqppesqsiegclgatCLAISRTAWNAIGGFDEEFFRYGEAADWQNRARAAGWRILLADEVgadrgnRVTgadaHVTGS 261
Cdd:COG1216   107 -----------------CLLIRREVFEEVGGFDERFFLYGEDVDLCLRLRKAGYRIVYVPDA------VVY----HLGGA 159

                         250
                  ....*....|....*
gi 1795718394 262 THEGAVAAAQHDRNR 276
Cdd:COG1216   160 SSGPLLRAYYLGRNR 174
GT_2_like_c cd04186
Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse ...
 28-240 8.52e-15

Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.


Pssm-ID: 133029 [Multi-domain]  Cd Length: 166  Bit Score: 72.59  E-value: 8.52e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394  28 VLIVSCKNHDGLQTCLHSVAEHLPK-LPVYVYDSrgGGRPGREELVARH-PAVHWVSGPVSRGFAAAFNTLVTHAPSDTd 105
Cdd:cd04186     1 IIIVNYNSLEYLKACLDSLLAQTYPdFEVIVVDN--ASTDGSVELLRELfPEVRLIRNGENLGFGAGNNQGIREAKGDY- 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 106 LLLLHADARVRGP--LTRTRELLRRPWVAAVSPMVCddtapgrppwdiaarrqtliralvaaagysdslrgmpispryar 183
Cdd:cd04186    78 VLLLNPDTVVEPGalLELLDAAEQDPDVGIVGPKVS-------------------------------------------- 113

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1795718394 184 qppesqsieGClgatCLAISRTAWNAIGGFDEEFFRYGEAADWQNRARAAGWRILLA 240
Cdd:cd04186   114 ---------GA----FLLVRREVFEEVGGFDEDFFLYYEDVDLCLRARLAGYRVLYV 157
PLN02871 PLN02871
UDP-sulfoquinovose:DAG sulfoquinovosyltransferase
 496-651 4.79e-13

UDP-sulfoquinovose:DAG sulfoquinovosyltransferase


Pssm-ID: 215469 [Multi-domain]  Cd Length: 465  Bit Score: 71.67  E-value: 4.79e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 496 GQP--PHLVMLSRIVEHKNPHLLVEALAGLTEMRwrLSIFGDGPDRERLQ---ARTPAELRDRVQWRGWSAgpgpALADA 570
Cdd:PLN02871  259 GEPekPLIVYVGRLGAEKNLDFLKRVMERLPGAR--LAFVGDGPYREELEkmfAGTPTVFTGMLQGDELSQ----AYASG 332

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 571 DLLCVPSRSEAFPLVILEAMAWAVPVAASAVCAVPEML---DFGRAGFVVEPVSVSGWREQLAKILADPAALPSVGRRGF 647
Cdd:PLN02871  333 DVFVMPSESETLGFVVLEAMASGVPVVAARAGGIPDIIppdQEGKTGFLYTPGDVDDCVEKLETLLADPELRERMGAAAR 412


                  ....
gi 1795718394 648 ERMQ 651
Cdd:PLN02871  413 EEVE 416
PelF NF038011
GT4 family glycosyltransferase PelF; Proteins of this family are components of the ...
 567-663 1.43e-07

GT4 family glycosyltransferase PelF; Proteins of this family are components of the exopolysaccharide Pel transporter. It has been reported that PelF is a soluble glycosyltransferase that uses UDP-glucose as the substrate for the synthesis of exopolysaccharide Pel, whereas PelG is a Wzx-like and PST family exopolysaccharide transporter.


Pssm-ID: 411604 [Multi-domain]  Cd Length: 489  Bit Score: 54.55  E-value: 1.43e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 567 LADADLLCVPSRSEAFPLVILEAMAWAVPVAASAVCAVPEML--------DFGRAGFVVEPVSVSGWREQLAKILADPAA 638
Cdd:NF038011  381 LPQVGLMVLSSISEALPLVVLEAFAAGVPVVTTDVGSCRQLIegldeedrALGAAGEVVAIADPQALARAALDLLRDPQR 460

                          90       100
                  ....*....|....*....|....*
gi 1795718394 639 LPSVGRRGFERMQQHYTVAAMADAY 663
Cdd:NF038011  461 WQAAQAAGLARVERYYTEELMFDRY 485
 
Name Accession Description Interval E-value
GT4_PimA-like cd03801
phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 ...
 331-667 4.31e-45

phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.


Pssm-ID: 340831 [Multi-domain]  Cd Length: 366  Bit Score: 165.02  E-value: 4.31e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 331 IVIVTNRL--VYGGAERQKALLATELDRRGYPVTIVCVQRFGPLINEIPHSVRVVRQPWWAPIVDIPA------GPAVLI 402
Cdd:cd03801     2 ILLLSPELppPVGGAERHVRELARALAARGHDVTVLTPADPGEPPEELEDGVIVPLLPSLAALLRARRllrelrPLLRLR 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 403 SGD----TNTETGFATLWRAAAKSRRWLVAAHIPPEDNRPIYSRPLTAAMRRADGFIVLAQRH--------WEMLTAHHR 470
Cdd:cd03801    82 KFDvvhaHGLLAALLAALLALLLGAPLVVTLHGAEPGRLLLLLAAERRLLARAEALLRRADAViavsealrDELRALGGI 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 471 LGGRRFVAPNGVAAAGDPAPPIRGVGQPPH---LVMLSRIVEHKNPHLLVEALAGLTEMR--WRLSIFG-DGPDRERLQA 544
Cdd:cd03801   162 PPEKIVVIPNGVDLERFSPPLRRKLGIPPDrpvLLFVGRLSPRKGVDLLLEALAKLLRRGpdVRLVIVGgDGPLRAELEE 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 545 RTpAELRDRVQWRGWSAGP--GPALADADLLCVPSRSEAFPLVILEAMAWAVPVAASAVCAVPEMLDFGRAGFVVEPVSV 622
Cdd:cd03801   242 LE-LGLGDRVRFLGFVPDEelPALYAAADVFVLPSRYEGFGLVVLEAMAAGLPVVATDVGGLPEVVEDGEGGLVVPPDDV 320

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*
gi 1795718394 623 SGWREQLAKILADPAALPSVGRRGFERMQQHYTVAAMADAYLDAI 667
Cdd:cd03801   321 EALADALLRLLADPELRARLGRAARERVAERFSWERVAERLLDLY 365
GT4_GT28_WabH-like cd03811
family 4 and family 28 glycosyltransferases similar to Klebsiella WabH; This family is most ...
 331-656 4.03e-38

family 4 and family 28 glycosyltransferases similar to Klebsiella WabH; This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core.


Pssm-ID: 340839 [Multi-domain]  Cd Length: 351  Bit Score: 144.81  E-value: 4.03e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 331 IVIVTNRLVYGGAERQKALLATELDRRGYPVTIVCvqRFGPLINEIPHSVRVVRQPWWAPIVDIPAG------------- 397
Cdd:cd03811     2 ILFVIPSLSGGGAERVLLNLANALDKRGYDVTLVL--LRDEGDLDKQLNGDVKLIRLLIRVLKLIKLgllkailklkril 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 398 ----PAVLISGDtntetGFATLWRAAAKSRRWLVAAHI---PPEDNRPIYSRPLTAAM-RRADGFIVLAQrhwEMLTAHH 469
Cdd:cd03811    80 krakPDVVISFL-----GFATYIVAKLAAARSKVIAWIhssLSKLYYLKKKLLLKLKLyKKADKIVCVSK---GIKEDLI 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 470 RLGGRR----FVAPNGV------AAAGDPAPPIRGvgQPPHLVMLSRIVEHKNPHLLVEALAGLTEMR--WRLSIFGDGP 537
Cdd:cd03811   152 RLGPSPpekiEVIYNPIdidrirALAKEPILNEPE--DGPVILAVGRLDPQKGHDLLIEAFAKLRKKYpdVKLVILGDGP 229

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 538 DRERLQARtpAE---LRDRVQWRGWSAGPGPALADADLLCVPSRSEAFPLVILEAMAWAVPVAASAVCAVPEMLDFGRAG 614
Cdd:cd03811   230 LREELEKL--AKelgLAERVIFLGFQSNPYPYLKKADLFVLSSRYEGFPNVLLEAMALGTPVVSTDCPGPREILDDGENG 307

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....
gi 1795718394 615 FVVEPVSVSGWREQLAKILADP--AALPSVGRRGFERMQQHYTV 656
Cdd:cd03811   308 LLVPDGDAAALAGILAALLQKKldAALRERLAKAQEAVFREYTI 351
GT4_AmsD-like cd03820
amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most ...
 331-652 1.40e-32

amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. AmSD in Erwinia amylovora has been shown to be involved in the biosynthesis of amylovoran, the acidic exopolysaccharide acting as a virulence factor. This enzyme may be responsible for the formation of galactose alpha-1,6 linkages in amylovoran.


Pssm-ID: 340847 [Multi-domain]  Cd Length: 351  Bit Score: 128.89  E-value: 1.40e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 331 IVIV-TNRLVYGGAERQKALLATELDRRGYPVTIVCV-QRFGPLINEIPHSVRVV---------RQPWWAPIVDIPA--- 396
Cdd:cd03820     2 IAIViPSISNAGGAERVAINLANHLAKKGYDVTIISLdSAEKPPFYELDDNIKIKnlgdrkyshFKLLLKYFKKVRRlrk 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 397 -----GPAVLISGDTNTETGFATLWRAAaksrRWLVAAHIPPEdNRPIYSRPLTA---AMRRADGFIVLAQRHWEmltAH 468
Cdd:cd03820    82 ylknnKPDVVISFRTSLLTFLALIGLKS----KLIVWEHNNYE-AYNKGLRRLLLrrlLYKRADKIVVLTEADKL---KK 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 469 HRLGGRRFVA-PNgvaaagdPAPPIRGVGQPP----HLVMLSRIVEHKNPHLLVEALAGLTEMR--WRLSIFGDGPDRER 541
Cdd:cd03820   154 YKQPNSNVVViPN-------PLSFPSEEPSTNlkskRILAVGRLTYQKGFDLLIEAWALIAKKHpdWKLRIYGDGPEREE 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 542 LQAR-TPAELRDRVQWRGWSAGPGPALADADLLCVPSRSEAFPLVILEAMAWAVPVAASAVCAVP-EMLDFGRAGFVVEP 619
Cdd:cd03820   227 LEKLiDKLGLEDRVKLLGPTKNIAEEYANSSIFVLSSRYEGFPMVLLEAMAYGLPIISFDCPTGPsEIIEDGENGLLVPN 306

                         330       340       350
                  ....*....|....*....|....*....|...
gi 1795718394 620 VSVSGWREQLAKILADPAALPSVGRRGFERMQQ 652
Cdd:cd03820   307 GDVDALAEALLRLMEDEELRKKMGKNARKNAER 339
Glyco_trans_1_4 pfam13692
Glycosyl transferases group 1;
498-635 6.94e-29

Glycosyl transferases group 1;


Pssm-ID: 463957 [Multi-domain]  Cd Length: 138  Bit Score: 111.83  E-value: 6.94e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 498 PPHLVMLSRIVE-HKNPHLLVEALAGL--TEMRWRLSIFGDGPDRErLQARTpAELRDRVQWRGWSAGPGPALADADLLC 574
Cdd:pfam13692   1 RPVILFVGRLHPnVKGVDYLLEAVPLLrkRDNDVRLVIVGDGPEEE-LEELA-AGLEDRVIFTGFVEDLAELLAAADVFV 78

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1795718394 575 VPSRSEAFPLVILEAMAWAVPVAASAVCAVPEMLDfGRAGFVVEPVSVSGWREQLAKILAD 635
Cdd:pfam13692  79 LPSLYEGFGLKLLEAMAAGLPVVATDVGGIPELVD-GENGLLVPPGDPEALAEAILRLLED 138
Glycos_transf_1 pfam00534
Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease ...
 498-649 1.37e-28

Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family.


Pssm-ID: 425737 [Multi-domain]  Cd Length: 158  Bit Score: 111.98  E-value: 1.37e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 498 PPHLVMLSRIVEHKNPHLLVEALAGLTEMR--WRLSIFGDGPDRERLQARTPA-ELRDRVQWRGWSAGPGPA--LADADL 572
Cdd:pfam00534   2 KKIILFVGRLEPEKGLDLLIKAFALLKEKNpnLKLVIAGDGEEEKRLKKLAEKlGLGDNVIFLGFVSDEDLPelLKIADV 81

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1795718394 573 LCVPSRSEAFPLVILEAMAWAVPVAASAVCAVPEMLDFGRAGFVVEPVSVSGWREQLAKILADPAALPSVGRRGFER 649
Cdd:pfam00534  82 FVLPSRYEGFGIVLLEAMACGLPVIASDVGGPPEVVKDGETGFLVKPNNAEALAEAIDKLLEDEELRERLGENARKR 158
GT4_CapM-like cd03808
capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This ...
 331-664 7.32e-27

capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. CapM in Staphylococcus aureus is required for the synthesis of type 1 capsular polysaccharides.


Pssm-ID: 340837 [Multi-domain]  Cd Length: 358  Bit Score: 112.69  E-value: 7.32e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 331 IVIVTNrlVYGGAERQKALLATELDRRGYPVTIVC-VQRFGP----LINEIPHSVRVVRQPWwAPIVDIPA--------- 396
Cdd:cd03808     2 ILFIVN--VDGGFQSFRLPLIKALVKKGYEVHVIApDGDKLSdelkELGVKVIDIPILRRGI-NPLKDLKAlfklykllk 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 397 --GPAVLISGDTNTETgFATLWRAAAKSRRWLVAAH------IPPEDNRPIYSRPLTAAMRRADGFIVLAQ--RHwEMLT 466
Cdd:cd03808    79 keKPDIVHCHTPKPGI-LGRLAARLAGVPKVIYTVHglgfvfTEGKLLRLLYLLLEKLALLFTDKVIFVNEddRD-LAIK 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 467 AHHRLGGRRFVAP-NGVAAAGDPAPPIRGVGQPPHLVMLSRIVEHKNPHLLVEALAGLTEM--RWRLSIFGDGPDRERLQ 543
Cdd:cd03808   157 KGIIKKKKTVLIPgSGVDLDRFQYSPESLPSEKVVFLFVARLLKDKGIDELIEAAKILKKKgpNVRFLLVGDGELENPSE 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 544 ART-PAELRDRVQWRGWSAGPGPALADADLLCVPSRSEAFPLVILEAMAWAVPVAASAVCAVPEMLDFGRAGFVVEPVSV 622
Cdd:cd03808   237 ILIeKLGLEGRIEFLGFRSDVPELLAESDVFVLPSYREGLPRSLLEAMAAGRPVITTDVPGCRELVIDGVNGFLVPPGDV 316

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|..
gi 1795718394 623 SGWREQLAKILADPAALPSVGRRGFERMQQHYTVAAMADAYL 664
Cdd:cd03808   317 EALADAIEKLIEDPELRKEMGEAARKRVEEKFDEEKVVNKLL 358
RfaB COG0438
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ...
 566-671 8.06e-26

Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440207 [Multi-domain]  Cd Length: 123  Bit Score: 102.76  E-value: 8.06e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 566 ALADADLLCVPSRSEAFPLVILEAMAWAVPVAASAVCAVPEMLDFGRAGFVVEPVSVSGWREQLAKILADPAALPSVGRR 645
Cdd:COG0438    17 LLAAADVFVLPSRSEGFGLVLLEAMAAGLPVIATDVGGLPEVIEDGETGLLVPPGDPEALAEAILRLLEDPELRRRLGEA 96

                          90       100
                  ....*....|....*....|....*.
gi 1795718394 646 GFERMQQHYTVAAMADAYLDAIDAVL 671
Cdd:COG0438    97 ARERAEERFSWEAIAERLLALYEELL 122
GT4_UGDG-like cd03817
UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins; This family is most ...
 331-649 1.32e-24

UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (EC 2.4.1.337, UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1,2-diacylglycerol forming 3-D-glucosyl-1,2-diacylglycerol.


Pssm-ID: 340844 [Multi-domain]  Cd Length: 372  Bit Score: 106.21  E-value: 1.32e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 331 IVIVTNrlVY----GGAERQKALLATELDRRGYPVTIVCVQRFGPLINEIPHSVRVVRQPWWAP---IVDIPAGPAVLIS 403
Cdd:cd03817     2 IAIFTD--TYlpqvNGVATSVRNLARALEKRGHEVYVITPSDPGAEDEEEVVRYRSFSIPIRKYhrqHIPFPFKKAVIDR 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 404 GD--------TNTE--TGFATLwRAAAKSRRWLVAA-HIPPED----------NRPIYSRPLTAAM-RRADGFIVLAQRH 461
Cdd:cd03817    80 IKelgpdiihTHTPfsLGKLGL-RIARKLKIPIVHTyHTMYEDylhyipkgklLVKAVVRKLVRRFyNHTDAVIAPSEKI 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 462 WEMLTAHHrLGGRRFVAPNGV------AAAGDPAPPIRGVGQ-PPHLVMLSRIVEHKNPHLLVEALAGL-TEMRWRLSIF 533
Cdd:cd03817   159 KDTLREYG-VKGPIEVIPNGIdldkfeKPLNTEERRKLGLPPdEPILLYVGRLAKEKNIDFLLRAFAELkKEPNIKLVIV 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 534 GDGPDRERLQAR-TPAELRDRVQWRGW--SAGPGPALADADLLCVPSRSEAFPLVILEAMAWAVPVAASAVCAVPEMLDF 610
Cdd:cd03817   238 GDGPEREELKELaRELGLADKVIFTGFvpREELPEYYKAADLFVFASTTETQGLVYLEAMAAGLPVVAAKDPAASELVED 317

                         330       340       350
                  ....*....|....*....|....*....|....*....
gi 1795718394 611 GRAGFVVEPVSVSgWREQLAKILADPAALPSVGRRGFER 649
Cdd:cd03817   318 GENGFLFEPNDET-LAEKLLHLRENLELLRKLSKNAEIS 355
GT4_WlbH-like cd03798
Bordetella parapertussis WlbH and similar proteins; This family is most closely related to the ...
 331-670 6.71e-24

Bordetella parapertussis WlbH and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Staphylococcus aureus CapJ may be involved in capsule polysaccharide biosynthesis. WlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core (band B), generates band A LPS.


Pssm-ID: 340828 [Multi-domain]  Cd Length: 376  Bit Score: 104.00  E-value: 6.71e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 331 IVIVT----NRLVYGGAERQKALLaTELDRRGYPVTIVCVQRFGPLI-----------NEIPHSVRVVRQPWWAPIVDIP 395
Cdd:cd03798     1 VLILTniypNANSPGRGIFVRRQV-RALSRRGVDVEVLAPAPWGPAAarllrkllgeaVPPRDGRRLLPLKPRLRLLAPL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 396 AGPAV-------------LISGDTNTETGFATLWRAAAKSRRWLVAAH---IPPEDNRPIYSRPLTAAMRRADGFIVLAQ 459
Cdd:cd03798    80 RAPSLakllkrrrrgppdLIHAHFAYPAGFAAALLARLYGVPYVVTEHgsdINVFPPRSLLRKLLRWALRRAARVIAVSK 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 460 RHWEMLTAHHRLGGRRFVAPNGVaaagDPA---PPIRGVGQPP-HLVMLS--RIVEHKNPHLLVEALAGLTEMRWRLS-- 531
Cdd:cd03798   160 ALAEELVALGVPRDRVDVIPNGV----DPArfqPEDRGLGLPLdAFVILFvgRLIPRKGIDLLLEAFARLAKARPDVVll 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 532 IFGDGPDRERLQA-RTPAELRDRVQWRGW-SAGPGPA-LADADLLCVPSRSEAFPLVILEAMAWAVPVAASAVCAVPEML 608
Cdd:cd03798   236 IVGDGPLREALRAlAEDLGLGDRVTFTGRlPHEQVPAyYRACDVFVLPSRHEGFGLVLLEAMACGLPVVATDVGGIPEVV 315

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1795718394 609 DFGRAGFVVEPVSVSGWREQLAKILADPaALPSVGRRGFERMQQHYTVAAMADAYLDAIDAV 670
Cdd:cd03798   316 GDPETGLLVPPGDADALAAALRRALAEP-YLRELGEAARARVAERFSWVKAADRIAAAYRDV 376
GT4_WbnK-like cd03807
Shigella dysenteriae WbnK and similar proteins; This family is most closely related to the GT4 ...
 331-665 2.99e-23

Shigella dysenteriae WbnK and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. WbnK in Shigella dysenteriae has been shown to be involved in the type 7 O-antigen biosynthesis.


Pssm-ID: 340836 [Multi-domain]  Cd Length: 362  Bit Score: 102.01  E-value: 2.99e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 331 IVIVTNRLVYGGAERQKALLATELDRRGYPVTIVCVQRFGPLINEIPHS-VRVV----------------------RQP- 386
Cdd:cd03807     2 VAHVITGLNVGGAETMLLRLLEHMDKSRFEHVVISLTGDGVLGEELLAAgVPVVclglssgkdpgvllrlaklirkRNPd 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 387 ---WWAPIVDIPAGPAVLISGDTNTETGF--ATLWRAAAKSRRWLvAAHIPPEDNRPIYSRPLTAAMRRADGFivlaqrh 461
Cdd:cd03807    82 vvhTWMYHADLIGGLAAKLAGGVKVIWSVrsSNIPQRLTRLVRKL-CLLLSKFSPATVANSSAVAEFHQEQGY------- 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 462 wemltAHHRLGgrrfVAPNGV------AAAGDPAPPIRGVGQP---PHLVMLSRIVEHKNPHLLVEALAGLTEMR--WRL 530
Cdd:cd03807   154 -----AKNKIV----VIYNGIdlfklsPDDASRARARRRLGLAedrRVIGIVGRLHPVKDHSDLLRAAALLVETHpdLRL 224

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 531 SIFGDGPDRERLQA-RTPAELRDRVQWRGWSAGPGPALADADLLCVPSRSEAFPLVILEAMAWAVPVAASAVCAVPEMLD 609
Cdd:cd03807   225 LLVGRGPERPNLERlLLELGLEDRVHLLGERSDVPALLPAMDIFVLSSRTEGFPNALLEAMACGLPVVATDVGGAAELVD 304

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1795718394 610 FGrAGFVVEPVSVSGWREQLAKILADPAALPSVGRRGFERMQQHYTVAAMADAYLD 665
Cdd:cd03807   305 DG-TGFLVPAGDPQALADAIRALLEDPEKRARLGRAARERIANEFSIDAMVRRYET 359
GT4_sucrose_synthase cd03800
sucrose-phosphate synthase and similar proteins; This family is most closely related to the ...
 446-665 8.66e-22

sucrose-phosphate synthase and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. The sucrose-phosphate synthases in this family may be unique to plants and photosynthetic bacteria. This enzyme catalyzes the synthesis of sucrose 6-phosphate from fructose 6-phosphate and uridine 5'-diphosphate-glucose, a key regulatory step of sucrose metabolism. The activity of this enzyme is regulated by phosphorylation and moderated by the concentration of various metabolites and light.


Pssm-ID: 340830 [Multi-domain]  Cd Length: 398  Bit Score: 98.08  E-value: 8.66e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 446 AAMRRADGFIVLAQRHWEMLTAHHRLGGRRF-VAPNGVAA-----AGDPAPPIRGVGQPPH---LVMLSRIVEHKNPHLL 516
Cdd:cd03800   159 QILEAADRVIASTPQEADELISLYGADPSRInVVPPGVDLerffpVDRAEARRARLLLPPDkpvVLALGRLDPRKGIDTL 238

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 517 VEALAGLTEMRW--RLSIFGdGPDRERLQARTPA--------ELRDRVQWRGwsAGPGPALAD----ADLLCVPSRSEAF 582
Cdd:cd03800   239 VRAFAQLPELRElaNLVLVG-GPSDDPLSMDREElaelaeelGLIDRVRFPG--RVSRDDLPElyraADVFVVPSLYEPF 315

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 583 PLVILEAMAWAVPVAASAVCAVPEMLDFGRAGFVVEPVSVSGWREQLAKILADPAALPSVGRRGFERMQQHYTVAAMADA 662
Cdd:cd03800   316 GLTAIEAMACGTPVVATAVGGLQDIVRDGRTGLLVDPHDPEALAAALRRLLDDPALWQRLSRAGLERARAHYTWESVADQ 395


                  ...
gi 1795718394 663 YLD 665
Cdd:cd03800   396 LLT 398
GT4_Bme6-like cd03821
Brucella melitensis Bme6 and similar proteins; This family is most closely related to the GT4 ...
 421-665 5.20e-21

Brucella melitensis Bme6 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Bme6 in Brucella melitensis has been shown to be involved in the biosynthesis of a polysaccharide.


Pssm-ID: 340848 [Multi-domain]  Cd Length: 377  Bit Score: 95.51  E-value: 5.20e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 421 KSRRWLVAAHIppednrpIYSRPLTAAmrraDGFIVLAQRHWEMLtahHRLG--GRRFVAPNGV-----AAAGDPAPPIR 493
Cdd:cd03821   134 KHWKKRIALHL-------IERRNLNNA----ALVHFTSEQEADEL---RRFGlePPIAVIPNGVdipefDPGLRDRRKHN 199

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 494 GVGQPPHLVMLSRIVEHKNPHLLVEALAGLTE--MRWRLSIFGDGPDRERLQARTPAE--LRDRVQWRGWSAGP--GPAL 567
Cdd:cd03821   200 GLEDRRIILFLGRIHPKKGLDLLIRAARKLAEqgRDWHLVIAGPDDGAYPAFLQLQSSlgLGDRVTFTGPLYGEakWALY 279

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 568 ADADLLCVPSRSEAFPLVILEAMAWAVPVAASAVCAVPEMLDFGrAGFVVEPvSVSGWREQLAKILADPAALPSVG--RR 645
Cdd:cd03821   280 ASADLFVLPSYSENFGNVVAEALACGLPVVITDKCGLSELVEAG-CGVVVDP-NVSSLAEALAEALRDPADRKRLGemAR 357

                         250       260
                  ....*....|....*....|
gi 1795718394 646 GFERMQQHYTVAAMADAYLD 665
Cdd:cd03821   358 RARQVEENFSWEAVAGQLGE 377
GT4_ExpE7-like cd03823
glycosyltransferase ExpE7 and similar proteins; This family is most closely related to the GT4 ...
 340-665 9.22e-21

glycosyltransferase ExpE7 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ExpE7 in Sinorhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucans (exopolysaccharide II).


Pssm-ID: 340850 [Multi-domain]  Cd Length: 357  Bit Score: 94.32  E-value: 9.22e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 340 YGGAERQKALLATELDRRGYPVTIVCVQRFGPLINEIPHSVRVVRQ-PWWAPIVDIPAGPAVLISGD------------- 405
Cdd:cd03823    14 VGGAEISVHDLAEALVAEGHEVAVLTAGVGPPGQATVARSVVRYRRaPDETLPLALKRRGYELFETYnpglrrllarlle 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 406 --------TNTETGFAT-LWRAAAK-SRRWLVAAHippeDNRPIYSRPltaAMRRADGFIVLAQRHWeMLTAHHRLGG-- 473
Cdd:cd03823    94 dfrpdvvhTHNLSGLGAsLLDAARDlGIPVVHTLH----DYWLLCPRQ---FLFKKGGDAVLAPSRF-TANLHEANGLfs 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 474 -RRFVAPNGVAAAGDPAPPIRGVGQPPHLVMLSRIVEHKNPHLLVEALAGLTEMRWRLSIFGDGPD--RERLQARTPAEL 550
Cdd:cd03823   166 aRISVIPNAVEPDLAPPPRRRPGTERLRFGYIGRLTEEKGIDLLVEAFKRLPREDIELVIAGHGPLsdERQIEGGRRIAF 245

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 551 RDRVQWrgwsAGPGPALADADLLCVPSR-SEAFPLVILEAMAWAVPVAASAVCAVPEMLDFGRAGFVVEPVSVSGWREQL 629
Cdd:cd03823   246 LGRVPT----DDIKDFYEKIDVLVVPSIwPEPFGLVVREAIAAGLPVIASDLGGIAELIQPGVNGLLFAPGDAEDLAAAM 321

                         330       340       350
                  ....*....|....*....|....*....|....*.
gi 1795718394 630 AKILADPAALPSVGRRGFERMQQHYTVAAMADAYLD 665
Cdd:cd03823   322 RRLLTDPALLERLRAGAEPPRSTESQAEEYLKLYRD 357
GT4_WavL-like cd03819
Vibrio cholerae WavL and similar sequences; This family is most closely related to the GT4 ...
 331-638 1.20e-19

Vibrio cholerae WavL and similar sequences; This family is most closely related to the GT4 family of glycosyltransferases. WavL in Vibrio cholerae has been shown to be involved in the biosynthesis of the lipopolysaccharide core.


Pssm-ID: 340846 [Multi-domain]  Cd Length: 345  Bit Score: 90.88  E-value: 1.20e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 331 IVIVTNRLVYGGAERQKALLATELDRRGYPVTIVC-----VQRFGPLINEIP-HSVRVVRQPWWAPIVDIPAG---PAVL 401
Cdd:cd03819     1 ILMLTPALEIGGAETYILDLARALAERGHRVLVVTaggplLPRLRQIGIGLPgLKVPLLRALLGNVRLARLIRrerIDLI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 402 isgDTNTetgFATLWRAAAKSRRW----------LVAAHIPPEDNRpiysrplTAAMRRADGFI-VLAQRHWEMLTAHHR 470
Cdd:cd03819    81 ---HAHS---RAPAWLGWLASRLTgvplvttvhgSYLATYHPKDFA-------LAVRARGDRVIaVSELVRDHLIEALGV 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 471 LGGRRFVAPNGV-------AAAGDPAPPIRGVGQPPHLVMLSRIVEHKNPHLLVEALAGLTEMR-WRLSIFGDGPDRERL 542
Cdd:cd03819   148 DPERIRVIPNGVdtdrfppEAEAEERAQLGLPEGKPVVGYVGRLSPEKGWLLLVDAAAELKDEPdFRLLVAGDGPERDEI 227

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 543 QAR-TPAELRDRVQWRGWSAGPGPALADADLLCVPSRSEAFPLVILEAMAWAVPVAASAVCAVPEMLDFGRAGFVVEPVS 621
Cdd:cd03819   228 RRLvERLGLRDRVTFTGFREDVPAALAASDVVVLPSLHEEFGRVALEAMACGTPVVATDVGGAREIVVHGRTGLLVPPGD 307

                         330
                  ....*....|....*..
gi 1795718394 622 VSGWREQLAKILADPAA 638
Cdd:cd03819   308 AEALADAIRAAKLLPEA 324
GT4-like cd03813
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family ...
 446-663 2.57e-19

glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.


Pssm-ID: 340841 [Multi-domain]  Cd Length: 474  Bit Score: 91.24  E-value: 2.57e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 446 AAMRRADGFIVLAQ--RHWEMltahhRLGG---RRFVAPNGV-AAAGDPAPPIRGVGQPPHLVMLSRIVEHKNPHLLVEA 519
Cdd:cd03813   240 LAYQQADKIISLYEgnRRRQI-----RLGAdpdKTRVIPNGIdIQRFAPAREERPEKEPPVVGLVGRVVPIKDVKTFIRA 314

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 520 LAGLTEMR--WRLSIFG---DGPD--RERLQARTPAELRDRVQWRGWsAGPGPALADADLLCVPSRSEAFPLVILEAMAW 592
Cdd:cd03813   315 FKLVRRAMpdAEGWLIGpedEDPEyaQECKRLVASLGLENKVKFLGF-QNIKEYYPKLGLLVLTSISEGQPLVILEAMAS 393

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1795718394 593 AVPVAASAVCAVPEML-----DFGRAGFVVEPVSVSGWREQLAKILADPAALPSVGRRGFERMQQHYTVAAMADAY 663
Cdd:cd03813   394 GVPVVATDVGSCRELIygaddALGQAGLVVPPADPEALAEALIKLLRDPELRQAFGEAGRKRVEKYYTLEGMIDSY 469
WcaE COG1216
Glycosyltransferase, GT2 family [Carbohydrate transport and metabolism];
25-276 3.60e-19

Glycosyltransferase, GT2 family [Carbohydrate transport and metabolism];


Pssm-ID: 440829 [Multi-domain]  Cd Length: 202  Bit Score: 86.20  E-value: 3.60e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394  25 SLAVLIVSCKNHDGLQTCLHSVAEH-LPKLPVYVYDSrgGGRPGREELVA--RHPAVHWVSGPVSRGFAAAFNTLVTHAP 101
Cdd:COG1216     4 KVSVVIPTYNRPELLRRCLESLLAQtYPPFEVIVVDN--GSTDGTAELLAalAFPRVRVIRNPENLGFAAARNLGLRAAG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 102 SDtDLLLLHADARVRgpltrtrellrrpwvaavspmvcddtapgrPPWdiaarrqtlIRALVAAAgysdslrgmpispry 181
Cdd:COG1216    82 GD-YLLFLDDDTVVE------------------------------PDW---------LERLLAAA--------------- 106

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 182 arqppesqsiegclgatCLAISRTAWNAIGGFDEEFFRYGEAADWQNRARAAGWRILLADEVgadrgnRVTgadaHVTGS 261
Cdd:COG1216   107 -----------------CLLIRREVFEEVGGFDERFFLYGEDVDLCLRLRKAGYRIVYVPDA------VVY----HLGGA 159

                         250
                  ....*....|....*
gi 1795718394 262 THEGAVAAAQHDRNR 276
Cdd:COG1216   160 SSGPLLRAYYLGRNR 174
GT4_MtfB-like cd03809
glycosyltransferases MtfB, WbpX, and similar proteins; This family is most closely related to ...
 331-665 2.37e-18

glycosyltransferases MtfB, WbpX, and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. MtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the previously synthesized polysaccharide.


Pssm-ID: 340838 [Multi-domain]  Cd Length: 362  Bit Score: 87.03  E-value: 2.37e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 331 IVIVTNRLV--YGGAERQKALLATELDRRGYPVTIVCVQ----------RFGPLINEIPHSVRVVRQPWW----APIVDI 394
Cdd:cd03809     2 ILIDGRSLAqrLTGIGRYTRELLKALAKNDPDESVLAVPplpgellrllREYPELSLGVIKIKLWRELALlrwlQILLPK 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 395 PAGPAVLISgdtnteTGFATLWRAaaKSRRWLVAAH--IP-------PEDNRPIYSRPLTAAMRRADGFIVLAQ--RHwE 463
Cdd:cd03809    82 KDKPDLLHS------PHNTAPLLL--KGCPQVVTIHdlIPlrypeffPKRFRLYYRLLLPISLRRADAIITVSEatRD-D 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 464 MLtahHRLGGRRF---VAPNGVAAAGDPAPP-----IRGVGQPPHLVMLSRIVEHKNPHLLVEALAGLTE--MRWRLSIF 533
Cdd:cd03809   153 II---KFYGVPPEkivVIPLGVDPSFFPPESaavliAKYLLPEPYFLYVGTLEPRKNHERLLKAFALLKKqgGDLKLVIV 229

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 534 G--DGPDRERLQARTPAELRDRVQWRGW-SAGPGPAL-ADADLLCVPSRSEAFPLVILEAMAWAVPVAASAVCAVPEMLd 609
Cdd:cd03809   230 GgkGWEDEELLDLVKKLGLGGRVRFLGYvSDEDLPALyRGARAFVFPSLYEGFGLPVLEAMACGTPVIASNISVLPEVA- 308

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1795718394 610 fGRAGFVVEPVSVSGWREQLAKILADPAALPSVGRRGFERMQQhYTVAAMADAYLD 665
Cdd:cd03809   309 -GDAALYFDPLDPESIADAILRLLEDPSLREELIRKGLERAKK-FSWEKTAEKTLE 362
Glycosyltransferase_GTB-type cd01635
glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases ...
 500-617 1.84e-17

glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


Pssm-ID: 340816 [Multi-domain]  Cd Length: 235  Bit Score: 82.07  E-value: 1.84e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 500 HLVMLSRIVEHKNPHLLVEALAGL--TEMRWRLSIFGDGPDRERLQARTPAE-LRDRVQWRGWSAGPGPA---LADADLL 573
Cdd:cd01635   112 DKVSVGRLVPEKGIDLLLEALALLkaRLPDLVLVLVGGGGEREEEEALAAALgLLERVVIIGGLVDDEVLellLAAADVF 191

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1795718394 574 CVPSRSEAFPLVILEAMAWAVPVAASAVCAVPEMLDFGRAGFVV 617
Cdd:cd01635   192 VLPSRSEGFGLVLLEAMAAGKPVIATDVGGIPEFVVDGENGLLV 235
GT4-like cd03814
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family ...
 499-653 7.79e-17

glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family of glycosyltransferases and includes a sequence annotated as alpha-D-mannose-alpha(1-6)phosphatidyl myo-inositol monomannoside transferase from Bacillus halodurans. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria and eukaryotes.


Pssm-ID: 340842 [Multi-domain]  Cd Length: 365  Bit Score: 82.73  E-value: 7.79e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 499 PHLVMLSRIVEHKNPHLLVEA-LAGLTEMRWRLSIFGDGPDRERLQARTPaelrdRVQWRGWSAGP--GPALADADLLCV 575
Cdd:cd03814   199 PLLLYVGRLAPEKNLEALLDAdLPLAASPPVRLVVVGDGPARAELEARGP-----DVIFTGFLTGEelARAYASADVFVF 273

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1795718394 576 PSRSEAFPLVILEAMAWAVPVAASAVCAVPEMLDFGRAGFVVEPVSVSGWREQLAKILADPAALPSVGRRGFERMQQH 653
Cdd:cd03814   274 PSRTETFGLVVLEAMASGLPVVAADAGGPRDIVRPGGTGALVEPGDAAAFAAALRALLEDPELRRRMAARARAEAERY 351
GT4-like cd05844
glycosyltransferase family 4 proteins; Glycosyltransferases catalyze the transfer of sugar ...
 440-654 3.57e-16

glycosyltransferase family 4 proteins; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to glycosyltransferase family 4 (GT4). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


Pssm-ID: 340860 [Multi-domain]  Cd Length: 365  Bit Score: 80.57  E-value: 3.57e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 440 YSRPLTAAMRRADGFIVLAQRHWEMLTAHHRLGGRRFVAPNGVaaagDPAP--PIRGVGQPPHLVMLSRIVEHKNPHLLV 517
Cdd:cd05844   133 FQRHRRALQRPAALFVAVSGFIRDRLLARGLPAERIHVHYIGI----DPAKfaPRDPAERAPTILFVGRLVEKKGCDVLI 208

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 518 EALAGLTEM--RWRLSIFGDGPDRERLQARtpAELRDRVQWRGWSAGP--GPALADADLLCVPS------RSEAFPLVIL 587
Cdd:cd05844   209 EAFRRLAARhpTARLVIAGDGPLRPALQAL--AAALGRVRFLGALPHAevQDWMRRAEIFCLPSvtaasgDSEGLGIVLL 286

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1795718394 588 EAMAWAVPVAASAVCAVPEMLDFGRAGFVVEPVSVSGWREQLAKILADPAALPSVGRRGFERMQQHY 654
Cdd:cd05844   287 EAAACGVPVVSSRHGGIPEAILDGETGFLVPEGDVDALADALQALLADRALADRMGGAARAFVCEQF 353
GT4_WcaC-like cd03825
putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins; This family ...
 446-665 4.10e-16

putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Escherichia coli WcaC has been predicted to function in colanic acid biosynthesis. WcfI in Bacteroides fragilis has been shown to be involved in the capsular polysaccharide biosynthesis.


Pssm-ID: 340851 [Multi-domain]  Cd Length: 364  Bit Score: 80.45  E-value: 4.10e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 446 AAMRRADGFIVLAQRhW--EMLTAHHRLGGRR-FVAPNGV-------AAAGDpAPPIRGVGQPPHLV-MLSRIVEH--KN 512
Cdd:cd03825   132 EALAKKRLTIVAPSR-WlaDMVRRSPLLKGLPvVVIPNGIdteifapVDKAK-ARKRLGIPQDKKVIlFGAESVTKprKG 209

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 513 PHLLVEALAGL-TEMRWRLSIFG-DGPDRERL--QARTPAELRDRVQWRGWsagpgpaLADADLLCVPSRSEAFPLVILE 588
Cdd:cd03825   210 FDELIEALKLLaTKDDLLLVVFGkNDPQIVILpfDIISLGYIDDDEQLVDI-------YSAADLFVHPSLADNLPNTLLE 282

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1795718394 589 AMAWAVPVAASAVCAVPEMLDFGRAGFVVEPVSVSGWREQLAKILADPAALPSVGRRGFERMQQHYTVAAMADAYLD 665
Cdd:cd03825   283 AMACGTPVVAFDTGGSPEIVQHGVTGYLVPPGDVQALAEAIEWLLANPKERESLGERARALAENHFDQRVQAQRYLE 359
GT4_AviGT4-like cd03802
UDP-Glc:tetrahydrobiopterin alpha-glucosyltransferase and similar proteins; This family is ...
 340-670 5.52e-16

UDP-Glc:tetrahydrobiopterin alpha-glucosyltransferase and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. aviGT4 in Streptomyces viridochromogenes has been shown to be involved in biosynthesis of oligosaccharide antibiotic avilamycin A. Inactivation of aviGT4 resulted in a mutant that accumulated a novel avilamycin derivative lacking the terminal eurekanate residue.


Pssm-ID: 340832 [Multi-domain]  Cd Length: 333  Bit Score: 79.64  E-value: 5.52e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 340 YGGAERQKALLATELDRRGYPVTIVC---VQRFGPLINEIPHSVRVVRQPWWAPIVDIPAGPAVLISGDT----NTETGF 412
Cdd:cd03802    17 YGGTELVVSALTEGLVRRGHEVTLFApgdSHTSAPLVAVIPRALRLDPIPQESKLAELLEALEVQLRASDfdviHNHSYD 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 413 ATLWRAAAKSRRWLVAAHIPPE-DNRPIYSRPltaaMRRADGFIVLAQRhwemltAHHRLGGRRFVAPNGVaaagDPAPP 491
Cdd:cd03802    97 WLPPFAPLIGTPFVTTLHGPSIpPSLAIYAAE----PPVNYVSISDAQR------AATPPIDYLTVVHNGL----DPADY 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 492 IRGVGQPPHLVMLSRIVEHKNPHLLVEALAGLtemRWRLSIFGDGPDRERLQARTPAELRDRVQWRGWSAGP--GPALAD 569
Cdd:cd03802   163 RFQPDPEDYLAFLGRIAPEKGLEDAIRVARRA---GLPLKIAGKVRDEDYFYYLQEPLPGPRIEFIGEVGHDekQELLGG 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 570 ADLLCVPSR-SEAFPLVILEAMAWAVPVAASAVCAVPEMLDFGRAGFVVEPVsvsgwrEQLAKILADPAALPSVGRRgfE 648
Cdd:cd03802   240 ARALLFPINwDEPFGLVMIEAMACGTPVIAYRRGGLPEVIQHGETGFLVDSV------EEMAEAIANIDRIDRAACR--R 311

                         330       340
                  ....*....|....*....|..
gi 1795718394 649 RMQQHYTVAAMADAYLDAIDAV 670
Cdd:cd03802   312 YAEDRFSAARMADRYEALYRKV 333
GT4_WbuB-like cd03794
Escherichia coli WbuB and similar proteins; This family is most closely related to the GT1 ...
 350-664 7.93e-16

Escherichia coli WbuB and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. WbuB in E. coli is involved in the biosynthesis of the O26 O-antigen. It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase.


Pssm-ID: 340825 [Multi-domain]  Cd Length: 391  Bit Score: 80.08  E-value: 7.93e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 350 LATELDRRGYPVTIVCVQRFGPLINEIPHSVRVVRQpwwAPIVDIPAGPavliSGDTNTETGFATLWRAAAKSRRWLVAA 429
Cdd:cd03794    23 LAKELVRRGHEVTVLTPSPNYPLGRIFAGATETKDG---IRVIRVKLGP----IKKNGLIRRLLNYLSFALAALLKLLVR 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 430 HIPPeDNRPIYSRPLTAAM------------------------------------------------RRADGFIVLAQRH 461
Cdd:cd03794    96 EERP-DVIIAYSPPITLGLaalllkklrgapfildvrdlwpeslialgvlkkgsllkllkklerklyRLADAIIVLSPGL 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 462 WEMLTAHHRLGGRRFVAPNGVAAAGDPAPPIRGVGQPPHL-----VMLSRIVEHK-NPHLLVEALAGLTEM-RWRLSIFG 534
Cdd:cd03794   175 KEYLLRKGVPKEKIIVIPNWADLEEFKPPPKDELRKKLGLddkfvVVYAGNIGKAqGLETLLEAAERLKRRpDIRFLFVG 254

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 535 DGPDRERLQARTPAELRDRVQWRGWsaGP----GPALADADLLCVPSRSE-----AFPLVILEAMAWAVPVAASAVCAVP 605
Cdd:cd03794   255 DGDEKERLKELAKARGLDNVTFLGR--VPkeevPELLSAADVGLVPLKDNpanrgSSPSKLFEYMAAGKPILASDDGGSD 332

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1795718394 606 EMLDFGRAGFVVEPVSVSGWREQLAKILADPAALPSVGRRGFERMQQHYTVAAMADAYL 664
Cdd:cd03794   333 LAVEINGCGLVVEPGDPEALADAILELLDDPELRRAMGENGRELAEEKFSREKLADRLL 391
GT4_BshA-like cd04962
N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA and similar proteins; This family is most ...
 529-666 1.48e-15

N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.


Pssm-ID: 340859 [Multi-domain]  Cd Length: 370  Bit Score: 78.93  E-value: 1.48e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 529 RLSIFGDGPDRERlqARTPAE---LRDRVQWRGWSAGPGPALADADLLCVPSRSEAFPLVILEAMAWAVPVAASAVCAVP 605
Cdd:cd04962   228 KLLLVGDGPERVP--AEELARelgVEDRVLFLGKQDDVEELLSIADLFLLPSEKESFGLAALEAMACGVPVVSSNAGGIP 305

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1795718394 606 EMLDFGRAGFVVEPVSVSGWREQLAKILADPAALPSVGRRGFERMQQHYTVAAMADAYLDA 666
Cdd:cd04962   306 EVVKHGETGFLSDVGDVDAMAKSALSILEDDELYNRMGRAARKRAAERFDPERIVPQYEAY 366
GT4_WfcD-like cd03795
Escherichia coli alpha-1,3-mannosyltransferase WfcD and similar proteins; This family is most ...
 504-660 3.59e-15

Escherichia coli alpha-1,3-mannosyltransferase WfcD and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP-linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria and eukaryotes.


Pssm-ID: 340826 [Multi-domain]  Cd Length: 355  Bit Score: 77.31  E-value: 3.59e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 504 LSRIVEHKNPHLLVEALAGLtemRWRLSIFGDGPDRERLQARTPAELRDRVQWRGwsagpgpALAD---------ADLLC 574
Cdd:cd03795   197 IGRLVYYKGLDYLIEAAQYL---NYPIVIGGEGPLKPDLEAQIELNLLDNVKFLG-------RVDDeekviylhlCDVFV 266

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 575 VPS--RSEAFPLVILEAMAWAVPVAASAV-CAVPEMLDFGRAGFVVEPVSVSGWREQLAKILADPAALPSVGRRGFERMQ 651
Cdd:cd03795   267 FPSvlRSEAFGIVLLEAMMCGKPVISTNIgTGVPYVNNNGETGLVVPPKDPDALAEAIDKLLSDEELRESYGENAKKRFE 346


                  ....*....
gi 1795718394 652 QHYTVAAMA 660
Cdd:cd03795   347 ELFTAEKMK 355
GT_2_like_c cd04186
Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse ...
 28-240 8.52e-15

Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.


Pssm-ID: 133029 [Multi-domain]  Cd Length: 166  Bit Score: 72.59  E-value: 8.52e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394  28 VLIVSCKNHDGLQTCLHSVAEHLPK-LPVYVYDSrgGGRPGREELVARH-PAVHWVSGPVSRGFAAAFNTLVTHAPSDTd 105
Cdd:cd04186     1 IIIVNYNSLEYLKACLDSLLAQTYPdFEVIVVDN--ASTDGSVELLRELfPEVRLIRNGENLGFGAGNNQGIREAKGDY- 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 106 LLLLHADARVRGP--LTRTRELLRRPWVAAVSPMVCddtapgrppwdiaarrqtliralvaaagysdslrgmpispryar 183
Cdd:cd04186    78 VLLLNPDTVVEPGalLELLDAAEQDPDVGIVGPKVS-------------------------------------------- 113

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1795718394 184 qppesqsieGClgatCLAISRTAWNAIGGFDEEFFRYGEAADWQNRARAAGWRILLA 240
Cdd:cd04186   114 ---------GA----FLLVRREVFEEVGGFDEDFFLYYEDVDLCLRARLAGYRVLYV 157
PLN02871 PLN02871
UDP-sulfoquinovose:DAG sulfoquinovosyltransferase
 496-651 4.79e-13

UDP-sulfoquinovose:DAG sulfoquinovosyltransferase


Pssm-ID: 215469 [Multi-domain]  Cd Length: 465  Bit Score: 71.67  E-value: 4.79e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 496 GQP--PHLVMLSRIVEHKNPHLLVEALAGLTEMRwrLSIFGDGPDRERLQ---ARTPAELRDRVQWRGWSAgpgpALADA 570
Cdd:PLN02871  259 GEPekPLIVYVGRLGAEKNLDFLKRVMERLPGAR--LAFVGDGPYREELEkmfAGTPTVFTGMLQGDELSQ----AYASG 332

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 571 DLLCVPSRSEAFPLVILEAMAWAVPVAASAVCAVPEML---DFGRAGFVVEPVSVSGWREQLAKILADPAALPSVGRRGF 647
Cdd:PLN02871  333 DVFVMPSESETLGFVVLEAMASGVPVVAARAGGIPDIIppdQEGKTGFLYTPGDVDDCVEKLETLLADPELRERMGAAAR 412


                  ....
gi 1795718394 648 ERMQ 651
Cdd:PLN02871  413 EEVE 416
GT4_AmsK-like cd03799
Erwinia amylovora AmsK and similar proteins; This is a family of GT4 glycosyltransferases ...
 496-654 6.15e-13

Erwinia amylovora AmsK and similar proteins; This is a family of GT4 glycosyltransferases found specifically in certain bacteria. AmsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor.


Pssm-ID: 340829 [Multi-domain]  Cd Length: 350  Bit Score: 70.56  E-value: 6.15e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 496 GQPPHLVMLSRIVEHKNPHLLVEALAGLTEM--RWRLSIFGDGPDRERLQ-ARTPAELRDRVQWRGWSAGPG--PALADA 570
Cdd:cd03799   172 DGKIRILTVGRLTEKKGLEYAIEAVAKLAQKypNIEYQIIGDGDLKEQLQqLIQELNIGDCVKLLGWKPQEEiiEILDEA 251

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 571 DLLCVPSRS------EAFPLVILEAMAWAVPVAASAVCAVPEMLDFGRAGFVVEPVSVSGWREQLAKILADPAALPSVGR 644
Cdd:cd03799   252 DIFIAPSVTaadgdqDGPPNTLKEAMAMGLPVISTEHGGIPELVEDGVSGFLVPERDAEAIAEKLTYLIEHPAIWPEMGK 331

                         170
                  ....*....|
gi 1795718394 645 RGFERMQQHY 654
Cdd:cd03799   332 AGRARVEEEY 341
PRK09922 PRK09922
lipopolysaccharide 1,6-galactosyltransferase;
491-634 1.16e-10

lipopolysaccharide 1,6-galactosyltransferase;


Pssm-ID: 182148 [Multi-domain]  Cd Length: 359  Bit Score: 63.58  E-value: 1.16e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 491 PIRGVGQPPHLVMLSRIV--EHKNPHLLVEALAgLTEMRWRLSIFGDGPDRERLQART-PAELRDRVQWRGWSAGPGPAL 567
Cdd:PRK09922  173 PPPERDKPAVFLYVGRLKfeGQKNVKELFDGLS-QTTGEWQLHIIGDGSDFEKCKAYSrELGIEQRIIWHGWQSQPWEVV 251

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1795718394 568 AD----ADLLCVPSRSEAFPLVILEAMAWAVP-VAASAVCAVPEMLDFGRAGFVVEPVSVSGWREQLAKILA 634
Cdd:PRK09922  252 QQkiknVSALLLTSKFEGFPMTLLEAMSYGIPcISSDCMSGPRDIIKPGLNGELYTPGNIDEFVGKLNKVIS 323
GT4_GtfA-like cd04949
accessory Sec system glycosyltransferase GtfA and similar proteins; This family is most ...
 448-596 6.45e-08

accessory Sec system glycosyltransferase GtfA and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases and is named after gtfA in Streptococcus gordonii, where it plays a role in the O-linked glycosylation of GspB, a cell surface glycoprotein involved in platelet binding. In general glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in bacteria.


Pssm-ID: 340855 [Multi-domain]  Cd Length: 328  Bit Score: 55.00  E-value: 6.45e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 448 MRRADGFIVLAQRHWEMLTAHHRLGGRRFVAPNGVAAAGDPapPIRGVGQPPHLVM-LSRIVEHKNPHLLVEALAGLTEM 526
Cdd:cd04949   111 LNKYDAIIVSTEQQKQDLSERFNKYPPIFTIPVGYVDQLDT--AESNHERKSNKIItISRLAPEKQLDHLIEAVAKAVKK 188

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1795718394 527 RWRLS--IFGDGPDRERLQARTPA-ELRDRVQWRGWSAGPGPALADADLLCVPSRSEAFPLVILEAMAWAVPV 596
Cdd:cd04949   189 VPEITldIYGYGEEREKLKKLIEElHLEDNVFLKGYHSNLDQEYQDAYLSLLTSQMEGFGLTLMEAIGHGLPV 261
PelF NF038011
GT4 family glycosyltransferase PelF; Proteins of this family are components of the ...
 567-663 1.43e-07

GT4 family glycosyltransferase PelF; Proteins of this family are components of the exopolysaccharide Pel transporter. It has been reported that PelF is a soluble glycosyltransferase that uses UDP-glucose as the substrate for the synthesis of exopolysaccharide Pel, whereas PelG is a Wzx-like and PST family exopolysaccharide transporter.


Pssm-ID: 411604 [Multi-domain]  Cd Length: 489  Bit Score: 54.55  E-value: 1.43e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 567 LADADLLCVPSRSEAFPLVILEAMAWAVPVAASAVCAVPEML--------DFGRAGFVVEPVSVSGWREQLAKILADPAA 638
Cdd:NF038011  381 LPQVGLMVLSSISEALPLVVLEAFAAGVPVVTTDVGSCRQLIegldeedrALGAAGEVVAIADPQALARAALDLLRDPQR 460

                          90       100
                  ....*....|....*....|....*
gi 1795718394 639 LPSVGRRGFERMQQHYTVAAMADAY 663
Cdd:NF038011  461 WQAAQAAGLARVERYYTEELMFDRY 485
GT5_Glycogen_synthase_DULL1-like cd03791
Glycogen synthase GlgA and similar proteins; This family is most closely related to the GT5 ...
 499-665 4.49e-07

Glycogen synthase GlgA and similar proteins; This family is most closely related to the GT5 family of glycosyltransferases. Glycogen synthase (EC:2.4.1.21) catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family includes starch synthases of plants, such as DULL1 in Zea mays and glycogen synthases of various organisms.


Pssm-ID: 340822 [Multi-domain]  Cd Length: 474  Bit Score: 52.95  E-value: 4.49e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 499 PHLVMLSRIVEHKNPHLLVEALAGLTEMRWRLSIFGDGPDR-ERLQARTPAELRDRVqwRGWsAGPGPAL-----ADADL 572
Cdd:cd03791   295 PLFGFVGRLTEQKGVDLILDALPELLEEGGQLVVLGSGDPEyEQAFRELAERYPGKV--AVV-IGFDEALahriyAGADF 371

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 573 LCVPSRSEAFPLVILEAMAW-AVPVaasaVCA-------VPEMLDFGRA--GFVVEPVSVSGWREQLAKILA---DPAAL 639
Cdd:cd03791   372 FLMPSRFEPCGLVQMYAMRYgTLPI----VRRtggladtVFDYDPETGEgtGFVFEDYDAEALLAALRRALAlyrNPELW 447

                         170       180
                  ....*....|....*....|....*.
gi 1795718394 640 PSVGRRGferMQQHYTVAAMADAYLD 665
Cdd:cd03791   448 RKLQKNA---MKQDFSWDKSAKEYLE 470
GT4_WbaZ-like cd03804
mannosyltransferase WbaZ and similar proteins; This family is most closely related to the GT4 ...
 502-626 6.32e-07

mannosyltransferase WbaZ and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. WbaZ in Salmonella enterica has been shown to possess mannosyltransferase activity.


Pssm-ID: 340833 [Multi-domain]  Cd Length: 356  Bit Score: 51.90  E-value: 6.32e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 502 VMLSRIVEHKNPHLLVEALaglTEMRWRLSIFGDGPDRERLQARTpaelRDRVQWRGWSagpgPALADADLLcvpSRSEA 581
Cdd:cd03804   203 LTASRLVPYKRIDLAVEAF---NELPKRLVVIGDGPDLDRLRAMA----SPNVEFLGYQ----PDEVLKELL---SKARA 268

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1795718394 582 --------FPLVILEAMAWAVPVAAsavcavpemldFGRAGfVVEPVS--VSGWR 626
Cdd:cd03804   269 fvfaaeedFGIVPVEAQACGTPVIA-----------FGKGG-ALETVRpgPTGIL 311
GT4_WbdM_like cd04951
LPS/UnPP-GlcNAc-Gal a-1,4-glucosyltransferase WbdM and similar proteins; This family is most ...
 506-621 3.16e-05

LPS/UnPP-GlcNAc-Gal a-1,4-glucosyltransferase WbdM and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases and is named after WbdM in Escherichia coli. In general glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in bacteria.


Pssm-ID: 340857 [Multi-domain]  Cd Length: 360  Bit Score: 46.67  E-value: 3.16e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 506 RIVEHKNPHLLVEALAGL--TEMRWRLSIFGDGPDRERLQaRTPAE--LRDRVQWRGWSAGPGPALADADLLCVPSRSEA 581
Cdd:cd04951   196 RLTEAKDYPNLLLAISELilSKNDFKLLIAGDGPLRNELE-RLICNlnLVDRVILLGQISNISEYYNAADLFVLSSEWEG 274

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1795718394 582 FPLVILEAMAWAVPVAASAVCAVPEMLdfGRAGFVVePVS 621
Cdd:cd04951   275 FGLVVAEAMACERPVVATDAGGVAEVV--GDHNYVV-PVS 311
GT4_AmsK-like cd04946
amylovoran biosynthesis glycosyltransferase AmsK and similar proteins; This family is most ...
 500-616 8.34e-05

amylovoran biosynthesis glycosyltransferase AmsK and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. AmsK is involved in the biosynthesis of amylovoran, which functions as a virulence factor. It functions as a glycosyl transferase which transfers galactose from UDP-galactose to a lipid-linked amylovoran-subunit precursor. The members of this family are found mainly in bacteria and Archaea.


Pssm-ID: 340854 [Multi-domain]  Cd Length: 401  Bit Score: 45.53  E-value: 8.34e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 500 HLVMLSRIVEHKNPHLLVEALAGLTEMRWRLSI----FGDGPDRERLQARTPAELRD-RVQWRGWSAGPGpALA-----D 569
Cdd:cd04946   226 RLVSCSSIVPVKRIDLIIETLNSLCVAHPSICIswthIGGGPLKERLEKLAENKLENvKVNFTGEVSNKE-VKQlykenD 304

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1795718394 570 ADLLCVPSRSEAFPLVILEAMAWAVPVAASAVCAVPEMLDFGRAGFV 616
Cdd:cd04946   305 VDVFVNVSESEGIPVSIMEAISFGIPVIATNVGGTREIVENETNGLL 351
Glyco_trans_1_2 pfam13524
Glycosyl transferases group 1;
573-665 1.64e-04

Glycosyl transferases group 1;


Pssm-ID: 433281 [Multi-domain]  Cd Length: 93  Bit Score: 41.05  E-value: 1.64e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 573 LCVPSRSEAFPLVILEAMAWAVPVAASAVCAVPEMLDFGRAGFVVEpvSVSGWREQLAKILADPAALPSVGRRGFERMQQ 652
Cdd:pfam13524   3 LNPSRRPDSPNMRVFEAAACGAPLLTDRTPGLEELFEPGEEILLYR--DPEELAEKIRYLLEHPEERRAIAAAGRERVLA 80

                          90
                  ....*....|...
gi 1795718394 653 HYTVAAMADAYLD 665
Cdd:pfam13524  81 EHTYAHRAEQLLD 93
PRK15179 PRK15179
Vi polysaccharide biosynthesis protein TviE; Provisional
 506-668 1.93e-04

Vi polysaccharide biosynthesis protein TviE; Provisional


Pssm-ID: 185101 [Multi-domain]  Cd Length: 694  Bit Score: 44.64  E-value: 1.93e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 506 RIVEHKNPHLLVEALAGLTEMR--WRLSIFGDGPDRERLQArTPAELR--DRVQWRGWSAGPGPALADADLLCVPSRSEA 581
Cdd:PRK15179  525 RVDDNKRPFLWVEAAQRFAASHpkVRFIMVGGGPLLESVRE-FAQRLGmgERILFTGLSRRVGYWLTQFNAFLLLSRFEG 603

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 582 FPLVILEAMAWAVPVAASAVCAVPEMLDFGRAGFVVEPVSVSG--WREQLAKILADPAALPSVGRRGFERMQQHYTVAAM 659
Cdd:PRK15179  604 LPNVLIEAQFSGVPVVTTLAGGAGEAVQEGVTGLTLPADTVTApdVAEALARIHDMCAADPGIARKAADWASARFSLNQM 683


                  ....*....
gi 1795718394 660 ADAYLDAID 668
Cdd:PRK15179  684 IASTVRCYQ 692
GT4_trehalose_phosphorylase cd03792
trehalose phosphorylase and similar proteins; Trehalose phosphorylase (TP) reversibly ...
 577-668 2.23e-04

trehalose phosphorylase and similar proteins; Trehalose phosphorylase (TP) reversibly catalyzes trehalose synthesis and degradation from alpha-glucose-1-phosphate (alpha-Glc-1-P) and glucose. The catalyzing activity includes the phosphorolysis of trehalose, which produce alpha-Glc-1-P and glucose, and the subsequent synthesis of trehalose. This family is most closely related to the GT4 family of glycosyltransferases.


Pssm-ID: 340823 [Multi-domain]  Cd Length: 378  Bit Score: 43.85  E-value: 2.23e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 577 SRSEAFPLVILEAMAWAVPVAASAVCAVPEMLDFGRAGFVVEpvSVSGWREQLAKILADPAALPSVGRRGFERMQQHYTV 656
Cdd:cd03792   287 STREGFGLTVSEALWKGKPVIATPAGGIPLQVIDGETGFLVN--SVEGAAVRILRLLTDPELRRKMGLAAREHVRDNFLI 364

                          90
                  ....*....|..
gi 1795718394 657 AAMADAYLDAID 668
Cdd:cd03792   365 TGNLRAWLYLIA 376
GT2_RfbF_like cd02526
RfbF is a putative dTDP-rhamnosyl transferase; Shigella flexneri RfbF protein is a putative ...
 87-243 2.56e-04

RfbF is a putative dTDP-rhamnosyl transferase; Shigella flexneri RfbF protein is a putative dTDP-rhamnosyl transferase. dTDP rhamnosyl transferases of Shigella flexneri add rhamnose sugars to N-acetyl-glucosamine in the O-antigen tetrasaccharide repeat. Lipopolysaccharide O antigens are important virulence determinants for many bacteria. The variations of sugar composition, the sequence of the sugars and the linkages in the O antigen provide structural diversity of the O antigen.


Pssm-ID: 133017 [Multi-domain]  Cd Length: 237  Bit Score: 43.04  E-value: 2.56e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394  87 RGFAAAFNTLVTHAPSD--TDLLLLHADAR-----VRGPLTRTRELLRRPWVAAVSPMVCDdtapgrppwdiaaRRQTLI 159
Cdd:cd02526    58 LGIAKALNIGIKAALENgaDYVLLFDQDSVpppdmVEKLLAYKILSDKNSNIGAVGPRIID-------------RRTGEN 124

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 160 RALVAAAGYSDslrgmPISPRYARQPPESQSI--EGCLgatclaISRTAWNAIGGFDEEFFRYGEAADWQNRARAAGWRI 237
Cdd:cd02526   125 SPGVRKSGYKL-----RIQKEGEEGLKEVDFLitSGSL------ISLEALEKVGGFDEDLFIDYVDTEWCLRARSKGYKI 193


                  ....*.
gi 1795718394 238 LLADEV 243
Cdd:cd02526   194 YVVPDA 199
PRK15484 PRK15484
lipopolysaccharide N-acetylglucosaminyltransferase;
570-636 5.32e-04

lipopolysaccharide N-acetylglucosaminyltransferase;


Pssm-ID: 185381 [Multi-domain]  Cd Length: 380  Bit Score: 42.85  E-value: 5.32e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1795718394 570 ADLLCVPSR-SEAFPLVILEAMAWAVPVAASAVCAVPEMLDFGRAGF-VVEPVSVSGWREQLAKILADP 636
Cdd:PRK15484  277 ADLVVVPSQvEEAFCMVAVEAMAAGKPVLASTKGGITEFVLEGITGYhLAEPMTSDSIISDINRTLADP 345
Succinoglycan_BP_ExoA cd02525
ExoA is involved in the biosynthesis of succinoglycan; Succinoglycan Biosynthesis Protein ExoA ...
 29-242 7.68e-04

ExoA is involved in the biosynthesis of succinoglycan; Succinoglycan Biosynthesis Protein ExoA catalyzes the formation of a beta-1,3 linkage of the second sugar (glucose) of the succinoglycan with the galactose on the lipid carrie. Succinoglycan is an acidic exopolysaccharide that is important for invasion of the nodules. Succinoglycan is a high-molecular-weight polymer composed of repeating octasaccharide units. These units are synthesized on membrane-bound isoprenoid lipid carriers, beginning with galactose followed by seven glucose molecules, and modified by the addition of acetate, succinate, and pyruvate. ExoA is a membrane protein with a transmembrance domain at c-terminus.


Pssm-ID: 133016 [Multi-domain]  Cd Length: 249  Bit Score: 41.83  E-value: 7.68e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394  29 LIVSCKN-HDGLQTCLHSVAE---HLPKLPVYVYDsrGGGRPGREELV----ARHPAVHWVSGPvSRGFAAAFNTLVTHA 100
Cdd:cd02525     4 IIIPVRNeEKYIEELLESLLNqsyPKDLIEIIVVD--GGSTDGTREIVqeyaAKDPRIRLIDNP-KRIQSAGLNIGIRNS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 101 PSDtdlLLLHADARVRGP---LTRTRELLRRPWVAAVSpmvcddtapGrpPWDIAARRQTLIRALVAaagySDSLRGMPI 177
Cdd:cd02525    81 RGD---IIIRVDAHAVYPkdyILELVEALKRTGADNVG---------G--PMETIGESKFQKAIAVA----QSSPLGSGG 142

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1795718394 178 SPRyaRQPPESQ--SIEGCLGAtclaISRTAWNAIGGFDEEFFRyGEAADWQNRARAAGWRILLADE 242
Cdd:cd02525   143 SAY--RGGAVKIgyVDTVHHGA----YRREVFEKVGGFDESLVR-NEDAELNYRLRKAGYKIWLSPD 202
GlgA COG0297
Glycogen synthase [Carbohydrate transport and metabolism];
501-665 8.06e-04

Glycogen synthase [Carbohydrate transport and metabolism];


Pssm-ID: 440066 [Multi-domain]  Cd Length: 476  Bit Score: 42.39  E-value: 8.06e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 501 LVMLSRIVEHKNPHLLVEALAGLTEMRWRLSIFGDGpDRE------RLQARTPaelrDRVqwrgwSAGPG--PALAD--- 569
Cdd:COG0297   298 IGMVSRLTEQKGLDLLLEALDELLEEDVQLVVLGSG-DPEyeeafrELAARYP----GRV-----AVYIGydEALAHriy 367

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 570 --ADLLCVPSRSEAFPLVILEAMAW-AVPVA------ASAVcaVPEMLDFGRA-GFVVEPVSVSGWREQLAKILA---DP 636
Cdd:COG0297   368 agADFFLMPSRFEPCGLNQMYALRYgTVPIVrrtgglADTV--IDYNEATGEGtGFVFDEYTAEALLAAIRRALAlyrDP 445

                         170       180
                  ....*....|....*....|....*....
gi 1795718394 637 AALPSVGRRGferMQQHYTVAAMADAYLD 665
Cdd:COG0297   446 EAWRKLQRNA---MKQDFSWEKSAKEYLE 471
Glyco_transf_4 pfam13439
Glycosyltransferase Family 4;
341-482 2.33e-03

Glycosyltransferase Family 4;


Pssm-ID: 463877 [Multi-domain]  Cd Length: 169  Bit Score: 39.44  E-value: 2.33e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 341 GGAERQKALLATELDRRGYPVTIVCVQRFGPLINEIPHSVRVVRQPWWA---PIVDIPAGPAV----------LISGDTN 407
Cdd:pfam13439   1 GGVERYVLELARALARRGHEVTVVTPGGPGPLAEEVVRVVRVPRVPLPLpprLLRSLAFLRRLrrllrrerpdVVHAHSP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 408 TETGFATLWRAAAKSRRWLVAAHIPPEDNRPIYSRP----------LTAAMRRADGFIVLAQRHWEMLTAHHRLGGRR-F 476
Cdd:pfam13439  81 FPLGLAALAARLRLGIPLVVTYHGLFPDYKRLGARLsplrrllrrlERRLLRRADRVIAVSEAVADELRRLYGVPPEKiR 160


                  ....*.
gi 1795718394 477 VAPNGV 482
Cdd:pfam13439 161 VIPNGV 166
GT4_ALG2-like cd03805
alpha-1,3/1,6-mannosyltransferase ALG2 and similar proteins; This family is most closely ...
 572-661 3.35e-03

alpha-1,3/1,6-mannosyltransferase ALG2 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ALG2, a 1,3-mannosyltransferase, in yeast catalyzes the mannosylation of Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. A deficiency of this enzyme causes an abnormal accumulation of Man1GlcNAc2-PP-dolichol and Man2GlcNAc2-PP-dolichol, which is associated with a type of congenital disorders of glycosylation (CDG), designated CDG-Ii, in humans.


Pssm-ID: 340834 [Multi-domain]  Cd Length: 392  Bit Score: 40.26  E-value: 3.35e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 572 LLCVPSRsEAFPLVILEAMAWAVPVAASAVCAVPEMLDFGRAGFVVEPVSVSgWREQLAKILADPAALPSVGRRGFERMQ 651
Cdd:cd03805   303 LLYTPSN-EHFGIVPLEAMYAGKPVIACNSGGPLETVVEGVTGFLCEPTPEA-FAEAMLKLANDPDLADRMGAAGRKRVK 380

                          90
                  ....*....|
gi 1795718394 652 QHYTVAAMAD 661
Cdd:cd03805   381 EKFSREAFAE 390
GT4_ExpC-like cd03818
Rhizobium meliloti ExpC and similar proteins; This family is most closely related to the GT4 ...
 586-665 5.40e-03

Rhizobium meliloti ExpC and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ExpC in Rhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucan (exopolysaccharide II).


Pssm-ID: 340845 [Multi-domain]  Cd Length: 396  Bit Score: 39.65  E-value: 5.40e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1795718394 586 ILEAMAWAVPVAASAVCAVPEMLDFGRAGFVVEPVSVSGWREQLAKILADPAALPSVGRRGFERMQQHYTVAAMADAYLD 665
Cdd:cd03818   317 LLEAMACGCPVIGSDTAPVREVIRDGRNGLLVDFFDPDALAAAVLELLEDPDRAAALRRAARRTVERSDSLDVCLARYLA 396
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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