|
Name |
Accession |
Description |
Interval |
E-value |
| recA |
PRK09354 |
recombinase A; Provisional |
5-221 |
3.05e-159 |
|
recombinase A; Provisional
Pssm-ID: 236476 [Multi-domain] Cd Length: 349 Bit Score: 443.85 E-value: 3.05e-159
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 5 ANLSAEKGKALAAALAQIEKQFGKGSIMRLGDGEVEaDIQVVSTGSLGLDIALGVGGLPRGRVIEIYGPESSGKTTLTLQ 84
Cdd:PRK09354 1 MAMDEEKQKALEAALKQIEKQFGKGSIMRLGDDAAM-DVEVISTGSLALDIALGIGGLPRGRIVEIYGPESSGKTTLALH 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 85 VVAEMQKLGGTCAFIDAEHALDVGYASKLGVSVPELLISQPDTGEQALEIADALVRSGSIDLIIIDSVAALVPKAEIEGE 164
Cdd:PRK09354 80 AIAEAQKAGGTAAFIDAEHALDPVYAKKLGVDIDNLLVSQPDTGEQALEIADTLVRSGAVDLIVVDSVAALVPKAEIEGE 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1735425040 165 MGDSLPGLQARLMSQALRKLTGTIKRTNCTVIFINQIRMKIGVMFGNPETTTGGNAL 221
Cdd:PRK09354 160 MGDSHVGLQARLMSQALRKLTGNISKSNTTVIFINQIREKIGVMFGNPETTTGGNAL 216
|
|
| RecA |
COG0468 |
RecA/RadA recombinase [Replication, recombination and repair]; |
8-221 |
2.42e-154 |
|
RecA/RadA recombinase [Replication, recombination and repair];
Pssm-ID: 440236 [Multi-domain] Cd Length: 351 Bit Score: 431.52 E-value: 2.42e-154
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 8 SAEKGKALAAALAQIEKQFGKGSIMRLGDGEVEaDIQVVSTGSLGLDIALGVGGLPRGRVIEIYGPESSGKTTLTLQVVA 87
Cdd:COG0468 7 SSEKEKALEAALSQIEKQFGKGSIMRLGDKARQ-DVEVISTGSLALDIALGVGGLPRGRIVEIYGPESSGKTTLALHAIA 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 88 EMQKLGGTCAFIDAEHALDVGYASKLGVSVPELLISQPDTGEQALEIADALVRSGSIDLIIIDSVAALVPKAEIEGEMGD 167
Cdd:COG0468 86 EAQKAGGIAAFIDAEHALDPEYAKKLGVDIDNLLVSQPDTGEQALEIAETLVRSGAVDLIVVDSVAALVPKAEIEGEMGD 165
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1735425040 168 SLPGLQARLMSQALRKLTGTIKRTNCTVIFINQIRMKIGVMFGNPETTTGGNAL 221
Cdd:COG0468 166 SHVGLQARLMSQALRKLTGAISKSNTTVIFINQLREKIGVMFGNPETTTGGNAL 219
|
|
| RecA |
pfam00154 |
recA bacterial DNA recombination protein; RecA is a DNA-dependent ATPase and functions in DNA ... |
21-221 |
1.33e-140 |
|
recA bacterial DNA recombination protein; RecA is a DNA-dependent ATPase and functions in DNA repair systems. RecA protein catalyzes an ATP-dependent DNA strand-exchange reaction that is the central step in the repair of dsDNA breaks by homologous recombination.
Pssm-ID: 425488 [Multi-domain] Cd Length: 262 Bit Score: 393.69 E-value: 1.33e-140
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 21 QIEKQFGKGSIMRLGDGEVEaDIQVVSTGSLGLDIALGVGGLPRGRVIEIYGPESSGKTTLTLQVVAEMQKLGGTCAFID 100
Cdd:pfam00154 9 QIEKQFGKGSIMKLGDEKKL-DVETISTGSLALDIALGIGGYPKGRIIEIYGPESSGKTTLALHAIAEAQKAGGTAAFID 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 101 AEHALDVGYASKLGVSVPELLISQPDTGEQALEIADALVRSGSIDLIIIDSVAALVPKAEIEGEMGDSLPGLQARLMSQA 180
Cdd:pfam00154 88 AEHALDPVYAKKLGVDIDNLLVSQPDTGEQALEIADMLVRSGAIDLIVVDSVAALVPKAEIEGEMGDSHVGLQARLMSQA 167
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 1735425040 181 LRKLTGTIKRTNCTVIFINQIRMKIGVMFGNPETTTGGNAL 221
Cdd:pfam00154 168 LRKLTGSISKSNTTVIFINQIREKIGVMFGNPETTTGGRAL 208
|
|
| tigrfam_recA |
TIGR02012 |
protein RecA; This model describes orthologs of the recA protein. RecA promotes hybridization ... |
10-221 |
8.04e-139 |
|
protein RecA; This model describes orthologs of the recA protein. RecA promotes hybridization of homolgous regions of DNA. A segment of ssDNA can be hybridized to another ssDNA region, or to a dsDNA region. ATP is hydrolyzed in the process. Part of the SOS respones, it is regulated by LexA via autocatalytic cleavage. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 162659 [Multi-domain] Cd Length: 321 Bit Score: 391.35 E-value: 8.04e-139
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 10 EKGKALAAALAQIEKQFGKGSIMRLGDGEVEaDIQVVSTGSLGLDIALGVGGLPRGRVIEIYGPESSGKTTLTLQVVAEM 89
Cdd:TIGR02012 1 DKQKALEAALAQIEKQFGKGSIMRLGEKTVM-DVETISTGSLALDLALGVGGLPKGRIIEIYGPESSGKTTLALHAIAEA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 90 QKLGGTCAFIDAEHALDVGYASKLGVSVPELLISQPDTGEQALEIADALVRSGSIDLIIIDSVAALVPKAEIEGEMGDSL 169
Cdd:TIGR02012 80 QKAGGTAAFIDAEHALDPVYARKLGVDIDNLLVSQPDTGEQALEIAETLVRSGAVDIIVVDSVAALVPKAEIEGEMGDSH 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1735425040 170 PGLQARLMSQALRKLTGTIKRTNCTVIFINQIRMKIGVMFGNPETTTGGNAL 221
Cdd:TIGR02012 160 VGLQARLMSQALRKLTGALSKSNTTAIFINQIREKIGVMFGNPETTTGGNAL 211
|
|
| RecA |
cd00983 |
recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ... |
42-221 |
4.00e-128 |
|
recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange.
Pssm-ID: 410863 [Multi-domain] Cd Length: 235 Bit Score: 360.72 E-value: 4.00e-128
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 42 DIQVVSTGSLGLDIALGVGGLPRGRVIEIYGPESSGKTTLTLQVVAEMQKLGGTCAFIDAEHALDVGYASKLGVSVPELL 121
Cdd:cd00983 1 DVEVIPTGSLSLDIALGIGGLPRGRIIEIYGPESSGKTTLALHAIAEAQKLGGTAAFIDAEHALDPEYAKKLGVDIDNLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 122 ISQPDTGEQALEIADALVRSGSIDLIIIDSVAALVPKAEIEGEMGDSLPGLQARLMSQALRKLTGTIKRTNCTVIFINQI 201
Cdd:cd00983 81 VSQPDTGEQALEIADTLIRSGAVDLIVVDSVAALVPKAEIEGEMGDSHVGLQARLMSQALRKLTGSLSKSKTTVIFINQL 160
|
170 180
....*....|....*....|
gi 1735425040 202 RMKIGVMFGNPETTTGGNAL 221
Cdd:cd00983 161 REKIGVMFGNPETTTGGNAL 180
|
|
| recA |
PRK09519 |
intein-containing recombinase RecA; |
8-221 |
3.08e-97 |
|
intein-containing recombinase RecA;
Pssm-ID: 77219 [Multi-domain] Cd Length: 790 Bit Score: 299.70 E-value: 3.08e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 8 SAEKGKALAAALAQIEKQFGKGSIMRLGDgEVEADIQVVSTGSLGLDIALGVGGLPRGRVIEIYGPESSGKTTLTLQVVA 87
Cdd:PRK09519 4 TPDREKALELAVAQIEKSYGKGSVMRLGD-EARQPISVIPTGSIALDVALGIGGLPRGRVIEIYGPESSGKTTVALHAVA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 88 EMQKLGGTCAFIDAEHALDVGYASKLGVSVPELLISQPDTGEQALEIADALVRSGSIDLIIIDSVAALVPKAEIEGEMGD 167
Cdd:PRK09519 83 NAQAAGGVAAFIDAEHALDPDYAKKLGVDTDSLLVSQPDTGEQALEIADMLIRSGALDIVVIDSVAALVPRAELEGEMGD 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1735425040 168 SLPGLQARLMSQALRKLTGTIKRTNCTVIFINQIRMKIGVMFGNPETTTGGNAL 221
Cdd:PRK09519 163 SHVGLQARLMSQALRKMTGALNNSGTTAIFINQLRDKIGVMFGSPETTTGGKAL 216
|
|
| RecA-like |
cd01393 |
RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ... |
65-221 |
1.56e-47 |
|
RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange. While prokaryotes have a single RecA protein, eukaryotes have multiple RecA homologs such as Rad51, DMC1 and Rad55/57. Archaea have the RecA-like homologs RadA and RadB.
Pssm-ID: 410881 [Multi-domain] Cd Length: 185 Bit Score: 154.82 E-value: 1.56e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 65 GRVIEIYGPESSGKTTLTLQVVAEMQKLGGTCAFIDAEHALDVGYA-----------SKLGVSVPELLISQPDTGEQALE 133
Cdd:cd01393 1 GKITEIYGPPGSGKTQLALQLAANALLLGGGVVWIDTEGAFPPSRLvqileaspsseLELAEALSRLLYFRPPDTLAHLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 134 IADALVRSGS----IDLIIIDSVAALVPKAEIEGEMGDSLPGLQARLMSQALRKLTGTIKRTNCTVIFINQIRMKIGVMF 209
Cdd:cd01393 81 ALDSLPESLFpppnTSLVVVDSVSALFRKAFPRGGDGDSSSSLRARLLSQLARALQKLAAQFNLAVVVTNQVTTKIRGGS 160
|
170
....*....|...
gi 1735425040 210 G-NPETTTGGNAL 221
Cdd:cd01393 161 GaSLVPPALGNTW 173
|
|
| archRadB |
cd01394 |
archaeal RadB; The archaeal protein RadB shares similarity RadA, the archaeal functional ... |
46-206 |
1.10e-17 |
|
archaeal RadB; The archaeal protein RadB shares similarity RadA, the archaeal functional homologue to the bacterial RecA. The precise function of RadB is unclear.
Pssm-ID: 410882 [Multi-domain] Cd Length: 216 Bit Score: 78.12 E-value: 1.10e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 46 VSTGSLGLDIALGvGGLPRGRVIEIYGPESSGKTTLTLQVVAEMQKLGGTCAFIDAEhALDVGYASKLGVSVPE-----L 120
Cdd:cd01394 1 LSTGSKSLDSLLG-GGVERGTITQIYGPPGSGKTNICLQLAVEAAKQGKKVVYIDTE-GLSPERFQQIAGERFEsiasnI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 121 LISQP-DTGEQALEIADA--LVRSGSIDLIIIDSVAALVpKAEiegEMGDSlpGLQARLMSQaLRKLTGTIKRTNCTVIF 197
Cdd:cd01394 79 IVFEPySFDEQGVAIQEAekLLKSDKVDLVVVDSATALY-RLE---LGDDS--EANRELSRQ-MSKLLSIARKYDIPVVI 151
|
....*....
gi 1735425040 198 INQIRMKIG 206
Cdd:cd01394 152 TNQVYSDID 160
|
|
| RAD55 |
COG0467 |
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms]; |
46-213 |
4.95e-15 |
|
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms];
Pssm-ID: 440235 [Multi-domain] Cd Length: 221 Bit Score: 71.10 E-value: 4.95e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 46 VSTGSLGLDIALGvGGLPRGRVIEIYGPESSGKTTLTLQVVAEMQKLGGTCAFIDAEHALD--VGYASKLGVSVPELL-- 121
Cdd:COG0467 2 VPTGIPGLDELLG-GGLPRGSSTLLSGPPGTGKTTLALQFLAEGLRRGEKGLYVSFEESPEqlLRRAESLGLDLEEYIes 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 122 -------ISQPDTGEQALEIADAL---VRSGSIDLIIIDSVAALVpkaeiegemgDSLPGLQARLmsQALRKLTGTIKRT 191
Cdd:COG0467 81 gllriidLSPEELGLDLEELLARLreaVEEFGAKRVVIDSLSGLL----------LALPDPERLR--EFLHRLLRYLKKR 148
|
170 180
....*....|....*....|..
gi 1735425040 192 NCTVIFINQIRMKIGVMFGNPE 213
Cdd:COG0467 149 GVTTLLTSETGGLEDEATEGGL 170
|
|
| radB |
PRK09361 |
DNA repair and recombination protein RadB; Provisional |
43-206 |
5.99e-13 |
|
DNA repair and recombination protein RadB; Provisional
Pssm-ID: 236482 [Multi-domain] Cd Length: 225 Bit Score: 65.27 E-value: 5.99e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 43 IQVVSTGSLGLDIALGvGGLPRGRVIEIYGPESSGKTTLTLQVVAEMQKLGGTCAFIDAEhALDVGYASKLGVSVPE--- 119
Cdd:PRK09361 2 DERLPTGCKMLDELLG-GGFERGTITQIYGPPGSGKTNICLQLAVEAAKNGKKVIYIDTE-GLSPERFKQIAGEDFEell 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 120 --LLISQP-DTGEQALEIADA--LVRSgSIDLIIIDSVAALVpKAEIEGEMGDSLpgLQARLMSQaLRKLTGTIKRTNCT 194
Cdd:PRK09361 80 snIIIFEPsSFEEQSEAIRKAekLAKE-NVGLIVLDSATSLY-RLELEDEEDNSK--LNRELGRQ-LTHLLKLARKHDLA 154
|
170
....*....|..
gi 1735425040 195 VIFINQIRMKIG 206
Cdd:PRK09361 155 VVITNQVYSDID 166
|
|
| XRCC3 |
cd19491 |
XRCC3 recombinase; XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells ... |
53-201 |
1.09e-12 |
|
XRCC3 recombinase; XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells 3) recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. XRCC3, together with the other RAD51 paralogs, RAD51B, RAD51C, RAD51D, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410899 [Multi-domain] Cd Length: 250 Bit Score: 65.01 E-value: 1.09e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 53 LDIALGvGGLPRGRVIEIYGPESSGKTTLTLQVVAEMQ------KLGGTCAFIDAEHAL----------------DVGYA 110
Cdd:cd19491 1 LDELLG-GGIPVGGITEIAGESGAGKTQLCLQLALTVQlprelgGLGGGAVYICTESSFpskrlqqlasslpkryHLEKA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 111 SKLGVSVPELLISQPDTGEQAL-EIADALVRSGSIDLIIIDSVAALVpKAEIEGEMGDSLpgLQARLMSQALRKLTGTIK 189
Cdd:cd19491 80 KNFLDNIFVEHVADLETLEHCLnYQLPALLERGPIRLVVIDSIAALF-RSEFDTSRSDLV--ERAKYLRRLADHLKRLAD 156
|
170
....*....|..
gi 1735425040 190 RTNCTVIFINQI 201
Cdd:cd19491 157 KYNLAVVVVNQV 168
|
|
| recomb_radB |
TIGR02237 |
DNA repair and recombination protein RadB; This family consists exclusively of archaeal RadB ... |
53-206 |
1.57e-12 |
|
DNA repair and recombination protein RadB; This family consists exclusively of archaeal RadB protein, a homolog of bacterial RecA (TIGR02012), eukaryotic RAD51 (TIGR02239) and DMC1 (TIGR02238), and archaeal RadA (TIGR02236).
Pssm-ID: 274047 [Multi-domain] Cd Length: 209 Bit Score: 63.97 E-value: 1.57e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 53 LDIALGvGGLPRGRVIEIYGPESSGKTTLTLQVVAEMQKLGGTCAFIDAEhALDVGYASKLGVSVPELLISQ------PD 126
Cdd:TIGR02237 1 IDELLG-GGVERGTITQIYGPPGSGKTNICMILAVNAARQGKKVVYIDTE-GLSPERFKQIAEDRPERALSNfivfevFD 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 127 TGEQALEIADA--LVRSGSIDLIIIDSVAALVpKAEIEGEMGDSLPGLQARlmsqaLRKLTGTIKRTNCTVIFINQIRMK 204
Cdd:TIGR02237 79 FDEQGVAIQKTskFIDRDSASLVVVDSFTALY-RLELSDDRISRNRELARQ-----LTLLLSLARKKNLAVVITNQVYTD 152
|
..
gi 1735425040 205 IG 206
Cdd:TIGR02237 153 VN 154
|
|
| COG4544 |
COG4544 |
Uncharacterized conserved protein [Function unknown]; |
33-150 |
5.41e-12 |
|
Uncharacterized conserved protein [Function unknown];
Pssm-ID: 443609 [Multi-domain] Cd Length: 230 Bit Score: 62.64 E-value: 5.41e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 33 RLGDGEVEADIQVVSTGSLGLDIALGVGGLPRGRVIEIYGPE-SSGKTTLTLQVVAEMQKLGGTCAFIDAEHALdvgYA- 110
Cdd:COG4544 16 WRGEGLAAAARAVLPTGFAALDAALPGGGLPRGALHEILGPApGIGELGLLLPLLARLAQAGGPVLWIAPPYDL---YAp 92
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 1735425040 111 --SKLGVSVPELLISQPDTGEQALEIADALVRSGSIDLIIID 150
Cdd:COG4544 93 glAAAGLDPERLLLVRARRPADALWAAEEALRSGACGAVVAW 134
|
|
| Rad51B |
cd19493 |
RAD51B recombinase; RAD51B recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
54-206 |
6.69e-12 |
|
RAD51B recombinase; RAD51B recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51B, together with the other RAD51 paralogs, RAD51C, RAD51D, XRCC3, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410901 [Multi-domain] Cd Length: 222 Bit Score: 62.34 E-value: 6.69e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 54 DIALGvGGLPRGRVIEIYGPESSGKT----TLTLQVVAEMQK--LGGTCAFIDAEHALDVGYASKLGVS-VPELLISQPD 126
Cdd:cd19493 1 DTALA-GGLPLGAITEITGASGSGKTqfalTLASSAAMPARKggLDGGVLYIDTESKFSAERLAEIAEArFPEAFSGFME 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 127 TGEQALEIAD--ALVRSGSID-------------------LIIIDSVAALVPKaeiegEMGDSLPGLQARlmSQALRKLT 185
Cdd:cd19493 80 ENERAEEMLKrvAVVRVTTLAqllerlpnleehilssgvrLVVIDSIAALVRR-----EFGGSDGEVTER--HNALAREA 152
|
170 180
....*....|....*....|....*
gi 1735425040 186 GTIKRT----NCTVIFINQIRMKIG 206
Cdd:cd19493 153 SSLKRLaeefRIAVLVTNQATTHFG 177
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
64-206 |
1.23e-11 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 60.46 E-value: 1.23e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 64 RGRVIEIYGPESSGKTTLTLQVVAEMQKLGGTCAFIDAEHALDVGYASKLGVSVPELLISqpDTGEQALEIADALVRSGS 143
Cdd:smart00382 1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIYIDGEDILEEVLDQLLLIIVGGKKAS--GSGELRLRLALALARKLK 78
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1735425040 144 IDLIIIDSVAALVPKAEiegemgdslpgLQARLMSQALRKLTGTIKRTNCTVIFINQIRMKIG 206
Cdd:smart00382 79 PDVLILDEITSLLDAEQ-----------EALLLLLEELRLLLLLKSEKNLTVILTTNDEKDLG 130
|
|
| radA |
PRK04301 |
DNA repair and recombination protein RadA; Validated |
42-221 |
6.67e-11 |
|
DNA repair and recombination protein RadA; Validated
Pssm-ID: 235273 [Multi-domain] Cd Length: 317 Bit Score: 60.66 E-value: 6.67e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 42 DIQVVSTGSLGLDIALGvGGLPRGRVIEIYGPESSGKTTLTLQVVAEMQK------LGGTCAFIDAEHALD----VGYAS 111
Cdd:PRK04301 80 NVGKITTGSKELDELLG-GGIETQSITEFYGEFGSGKTQICHQLAVNVQLpeekggLEGKAVYIDTEGTFRperiEQMAE 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 112 KLGVSVPELL-----ISQPDTGEQAL--EIADALVRSG-SIDLIIIDSVAALVpKAEIEGEmgDSLPGLQARLMSQ--AL 181
Cdd:PRK04301 159 ALGLDPDEVLdnihvARAYNSDHQMLlaEKAEELIKEGeNIKLVIVDSLTAHF-RAEYVGR--GNLAERQQKLNKHlhDL 235
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 1735425040 182 RKLTGTIkrtNCTVIFINQIRMKIGVMFGNPETTTGGNAL 221
Cdd:PRK04301 236 LRLADLY---NAAVVVTNQVMARPDAFFGDPTQPIGGHIL 272
|
|
| KaiC-like |
cd01124 |
Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. ... |
46-202 |
7.14e-11 |
|
Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.
Pssm-ID: 410869 [Multi-domain] Cd Length: 222 Bit Score: 59.58 E-value: 7.14e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 46 VSTGSLGLDIALGvGGLPRGRVIEIYGPESSGKTTLTLQVVAEMQKLGGTCAFIDAE--------HALDVGYASKLGVSV 117
Cdd:cd01124 1 VKTGIPGLDELLG-GGIPKGSVTLLTGGPGTGKTLFGLQFLYAGAKNGEPGLFFTFEesperllrNAKSFGWDFDEMEDE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 118 PELLISQPDTGEQALEIADAL-------VRSGSIDLIIIDSVAALvpkaeiegemgdSLPGLQARLMSQALRKLTGTIKR 190
Cdd:cd01124 80 GKLIIVDAPPTEAGRFSLDELlsrilsiIKSFKAKRVVIDSLSGL------------RRAKEDQMRARRIVIALLNELRA 147
|
170
....*....|..
gi 1735425040 191 TNCTVIFINQIR 202
Cdd:cd01124 148 AGVTTIFTSEMR 159
|
|
| archRadA |
cd19515 |
archaeal recombinase Rad51/RadA; This group includes the archaeal protein RadA which is a ... |
46-221 |
1.79e-10 |
|
archaeal recombinase Rad51/RadA; This group includes the archaeal protein RadA which is a homolog of Rad51. RAD51 recombinase plays an essential role in DNA repair by homologous recombination (HR)
Pssm-ID: 410923 [Multi-domain] Cd Length: 233 Bit Score: 58.53 E-value: 1.79e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 46 VSTGSLGLDIALGvGGLPRGRVIEIYGPESSGKTTLTLQVVAEMQK------LGGTCAFIDAEHALD----VGYASKLGV 115
Cdd:cd19515 1 ISTGSKELDKLLG-GGIETQAITEVFGEFGSGKTQLCHQLAVNVQLppeeggLNGKAVYIDTENTFRperiMQMAKALGL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 116 SVPELL-----ISQPDTGEQAL---EIADALVRSGSIDLIIIDSVAALVpKAEIEGEmgDSLPGLQARLmSQALRKLTGT 187
Cdd:cd19515 80 DPDEVLdniyvARAYNSNHQMLlveKAEDLIKEGNNIKLLIVDSLTSHF-RAEYVGR--GTLAERQQKL-NKHLHDLHRL 155
|
170 180 190
....*....|....*....|....*....|....
gi 1735425040 188 IKRTNCTVIFINQIRMKIGVMFGNPETTTGGNAL 221
Cdd:cd19515 156 ADLYNIAVLVTNQVMAKPDAFFGDPTQAIGGHIL 189
|
|
| Rad51 |
pfam08423 |
Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ... |
46-221 |
2.87e-10 |
|
Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ATPase RecA protein.
Pssm-ID: 462471 [Multi-domain] Cd Length: 255 Bit Score: 58.47 E-value: 2.87e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 46 VSTGSLGLDIALGvGGLPRGRVIEIYGPESSGKTTL--TLQVVA----EMQKLGGTCAFIDAEHALD----VGYASKLGV 115
Cdd:pfam08423 19 ITTGSKELDKLLG-GGIETGSITEIFGEFRTGKTQLchTLCVTCqlplEMGGGEGKALYIDTEGTFRperlVAIAERYGL 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 116 SVPELLISQP-------DTGEQALEIADALVRSGSIDLIIIDSVAALVpKAEIEGEmGDslpgLQARLM--SQALRKLTG 186
Cdd:pfam08423 98 DPEDVLDNVAyaraynsEHQMQLLQQAAAMMSESRFALLIVDSATALY-RTDFSGR-GE----LAERQQhlAKFLRTLQR 171
|
170 180 190
....*....|....*....|....*....|....*....
gi 1735425040 187 TIKRTNCTVIFINQIRMKIG---VMF-GNPETTTGGNAL 221
Cdd:pfam08423 172 LADEFGVAVVITNQVVAQVDgaaGMFsGDPKKPIGGHIM 210
|
|
| RepA |
COG3598 |
RecA-family ATPase [Replication, recombination and repair]; |
62-198 |
4.88e-10 |
|
RecA-family ATPase [Replication, recombination and repair];
Pssm-ID: 442817 [Multi-domain] Cd Length: 313 Bit Score: 57.99 E-value: 4.88e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 62 LPRGRVIEIYGPESSGKTTLTLQVVAEMQK----LG-----GTCAFIDAE----------HALDVGYASKLGVSVPELLI 122
Cdd:COG3598 10 LPEGGVTLLAGPPGTGKSFLALQLAAAVAAggpwLGrrvppGKVLYLAAEddrgelrrrlKALGADLGLPFADLDGRLRL 89
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1735425040 123 SQPDTGEQALEIADAL---VRSGSIDLIIIDSVAALVPKAEIEGEmgdslpglQARLMSQALRKLtgtIKRTNCTVIFI 198
Cdd:COG3598 90 LSLAGDLDDTDDLEALeraIEEEGPDLVVIDPLARVFGGDENDAE--------EMRAFLNPLDRL---AERTGAAVLLV 157
|
|
| RadA_SMS_N |
cd01121 |
bacterial RadA DNA repair protein; Sms or bacterial RadA is a DNA repair protein that plays a ... |
32-198 |
2.62e-09 |
|
bacterial RadA DNA repair protein; Sms or bacterial RadA is a DNA repair protein that plays a role in recombination and recombinational repair of DNA damaged by UV radiation, X-rays, and chemical agent and is responsible for the stabilization or processing of branched DNA molecules.
Pssm-ID: 410866 [Multi-domain] Cd Length: 268 Bit Score: 55.62 E-value: 2.62e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 32 MRLGDGEVEaDIQVVSTGSLGLDIALGvGGLPRGRVIEIYGPESSGKTTLTLQVVAEMQKLGGTCAFIDAEHALD--VGY 109
Cdd:cd01121 51 LPLSDVEAE-EEERISTGIGELDRVLG-GGLVPGSVVLIGGDPGIGKSTLLLQVAARLAQRGGKVLYVSGEESLSqiKLR 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 110 ASKLGVSVPELLIsqpdTGEQALEIADALVRSGSIDLIIIDSVAALVPKAEiegemgDSLPG--LQARLMSQALRKLTgt 187
Cdd:cd01121 129 AERLGLGSDNLYL----LAETNLEAILAEIEELKPSLVVIDSIQTVYSPEL------TSSPGsvSQVRECAAELLRLA-- 196
|
170
....*....|.
gi 1735425040 188 iKRTNCTVIFI 198
Cdd:cd01121 197 -KETGIPVFLV 206
|
|
| ATPase |
pfam06745 |
KaiC; This family is in the P-loop NTPase superfamily and is found in archaea, bacteria and ... |
46-203 |
4.91e-09 |
|
KaiC; This family is in the P-loop NTPase superfamily and is found in archaea, bacteria and eukaryotes. More than one copy is sometimes found in each protein. This family includes KaiC, which is one of the Kai proteins among which direct protein-protein association may be a critical process in the generation of circadian rhythms in cyanobacteria.
Pssm-ID: 429095 [Multi-domain] Cd Length: 231 Bit Score: 54.56 E-value: 4.91e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 46 VSTGSLGLDIALGvGGLPRGRVIEIYGPESSGKTTLTLQ-VVAEMQKLGGTCAFIDA-EHALDV-GYASKLGVSVPELL- 121
Cdd:pfam06745 1 VKTGIPGLDEILK-GGFPEGRVVLITGGPGTGKTIFGLQfLYNGALKYGEPGVFVTLeEPPEDLrENARSFGWDLEKLEe 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 122 --------ISQPDTGEQALEIADAL----------VRSGSIDLIIIDSVAALvpkAEIEGEMgdslpglQARlmsQALRK 183
Cdd:pfam06745 80 egklaiidASTSGIGIAEVEDRFDLeelierlreaIREIGAKRVVIDSITTL---FYLLKPA-------VAR---EILRR 146
|
170 180
....*....|....*....|
gi 1735425040 184 LTGTIKRTNCTVIFINQIRM 203
Cdd:pfam06745 147 LKRVLKGLGVTAIFTSEKPS 166
|
|
| Rad51_DMC1_archRadA |
cd01123 |
recombinase Rad51, DMC1, and archaeal RadA; This group of recombinases includes the eukaryotic ... |
46-221 |
6.86e-09 |
|
recombinase Rad51, DMC1, and archaeal RadA; This group of recombinases includes the eukaryotic proteins RAD51, RAD55/57 and the meiosis-specific protein DMC1, and the archaeal protein RadA. They are closely related to the bacterial RecA group. Rad51 proteins catalyze a similar recombination reaction as RecA, using ATP-dependent DNA binding activity and a DNA-dependent ATPase. However, this reaction is less efficient and requires accessory proteins such as RAD55/57 .
Pssm-ID: 410868 [Multi-domain] Cd Length: 234 Bit Score: 54.07 E-value: 6.86e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 46 VSTGSLGLDIALGvGGLPRGRVIEIYGPESSGKTTL------TLQVVAEMQKLGGTCAFIDAEHALD----VGYASKLGV 115
Cdd:cd01123 1 ITTGSKELDKLLG-GGIETGSITEMFGEFRTGKTQLchtlavTCQLPIDRGGGEGKAIYIDTEGTFRperlRAIAQRFGL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 116 SVPELLIS-------QPDTGEQALEIADALVRSGSIDLIIIDSVAALVpKAEIEGEmGDslpgLQARLM--SQALRKLTG 186
Cdd:cd01123 80 DPDDVLDNvayarafNSDHQTQLLDQAAAMMVESRFKLLIVDSATALY-RTDYSGR-GE----LSARQMhlAKFLRMLQR 153
|
170 180 190
....*....|....*....|....*....|....*...
gi 1735425040 187 TIKRTNCTVIFINQIRMKIG---VMFGNPETTTGGNAL 221
Cdd:cd01123 154 LADEFGVAVVVTNQVVAQVDgamMFAADPKKPIGGNIL 191
|
|
| XRCC2 |
cd19490 |
XRCC2 recombinase; XRCC2 (X-ray repair complementing defective repair in Chinese hamster cells ... |
65-206 |
1.45e-08 |
|
XRCC2 recombinase; XRCC2 (X-ray repair complementing defective repair in Chinese hamster cells 2) recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. XRCC2, together with the other RAD51 paralogs, RAD51B, RAD51C, RAD51D, and XRCC3, helps recruit RAD51 to the break site.
Pssm-ID: 410898 [Multi-domain] Cd Length: 226 Bit Score: 53.12 E-value: 1.45e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 65 GRVIEIYGPESSGKTTLTLQVVA-----------EMQKLGGTCAFIDAEHALDVgyaSKLgVSVPELLISQ-------PD 126
Cdd:cd19490 1 GDVIEITGPSGSGKTELLYHLAArcilpsswggvPLGGLEAAVVFIDTDGRFDI---LRL-RSILEARIRAaiqaansSD 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 127 TGEQALEIADA------LVRSGSID-----------------------LIIIDSVAALVPKAEIEGEMGDSLPGLQARLM 177
Cdd:cd19490 77 DEEDVEEIAREclqrlhIFRCHSSLqllatllslenyllslsanpelgLLLIDSISAFYWQDRFSAELARAAPLLQEAAL 156
|
170 180 190
....*....|....*....|....*....|..
gi 1735425040 178 ---SQALRKLTgtiKRTNCTVIFINQIRMKIG 206
Cdd:cd19490 157 raiLRELRRLR---RRFQLVVIATKQALFPGK 185
|
|
| Rad51C |
cd19492 |
RAD51C recombinase; RAD51C recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
65-206 |
1.59e-08 |
|
RAD51C recombinase; RAD51C recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51C, together with the other RAD51 paralogs, RAD51B, RAD51D, XRCC3, and XRCC2, helps recruit RAD51 to the break site. Additionally, RAD51C acts as a mediator in the early steps of DNA damage signaling.
Pssm-ID: 410900 [Multi-domain] Cd Length: 172 Bit Score: 52.23 E-value: 1.59e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 65 GRVIEIYGPESSGKTTLTLQVVAEMQ------KLGGTCAFIDAE-----HALDV-GYASKLGV--SVPELLISQPDtgeq 130
Cdd:cd19492 1 GKITEICGVPGVGKTQLCMQLAVNVQipkcfgGLAGEAIYIDTEgsfniHYFRVhDYVELLALinSLPKFLEDHPK---- 76
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1735425040 131 aleiadalvrsgsIDLIIIDSVAALVpKAEIEGemgdslPGLQARLMSQALRKLTGTIKRTNCTVIFINQIRMKIG 206
Cdd:cd19492 77 -------------VKLIVVDSIAFPF-RHDFDD------LAQRTRLLNGLAQLLHSLARQHNLAVVLTNQVTTKIS 132
|
|
| KaiC-like_N |
cd19488 |
N-terminal domain of KaiC family protein; uncharacterized subfamily; KaiC is a circadian clock ... |
46-99 |
4.18e-07 |
|
N-terminal domain of KaiC family protein; uncharacterized subfamily; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.
Pssm-ID: 410896 [Multi-domain] Cd Length: 225 Bit Score: 48.88 E-value: 4.18e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 1735425040 46 VSTGSLGLDIALGvGGLPRGRVIEIYGPESSGKTTLTLQVVAEMQKLGGTCAFI 99
Cdd:cd19488 1 ISTGIPGLDDILR-GGLPPRRLYLVEGAPGTGKTTLALQFLLEGAANGETGLYI 53
|
|
| RecA-like_superfamily |
cd01120 |
RecA-like_NTPases; RecA-like NTPases. This superfamily includes the NTP binding domain of F1 ... |
68-221 |
5.15e-07 |
|
RecA-like_NTPases; RecA-like NTPases. This superfamily includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410865 [Multi-domain] Cd Length: 119 Bit Score: 47.11 E-value: 5.15e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 68 IEIYGPESSGKTTLTLQVVAEMQKLGGTCAFIDAehaLDVgyasklgvsvpellisqpdtgeqALEIADALVRSGSIDLI 147
Cdd:cd01120 1 ILITGPPGSGKTTLLLQFAEQALLSDEPVIFISF---LDT-----------------------ILEAIEDLIEEKKLDII 54
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1735425040 148 IIDSVAALVPKaeiegemgdsLPGLQARLMSQALRKLTGTIKRTNCTVIFINQIRMKIGVMFGNPETTTGGNAL 221
Cdd:cd01120 55 IIDSLSSLARA----------SQGDRSSELLEDLAKLLRAARNTGITVIATIHSDKFDIDRGGSSNDERLLKSL 118
|
|
| Rad51 |
cd19513 |
RAD51D recombinase; RAD51 recombinase plays an essential role in DNA repair by homologous ... |
46-219 |
9.35e-07 |
|
RAD51D recombinase; RAD51 recombinase plays an essential role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51 is recruited to the break site with the help of its paralogs, RAD51D, RAD51B, RAD51C, XRCC3, and XRCC2, where it forms long helical polymers which wrap around the ssDNA tail at the break which leads to pairing and strand invasion.
Pssm-ID: 410921 [Multi-domain] Cd Length: 235 Bit Score: 48.08 E-value: 9.35e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 46 VSTGSLGLDIALGvGGLPRGRVIEIYGPESSGKTTL------TLQVVAEMQKLGGTCAFIDAEHALD----VGYASKLGV 115
Cdd:cd19513 1 ITTGSKELDKLLG-GGIETGSITELFGEFRTGKTQLchtlavTCQLPIDQGGGEGKALYIDTEGTFRperlLAIAERYGL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 116 SVPELLIS-------QPDTGEQALEIADALVRSGSIDLIIIDSVAALVpKAEIEGEmGDslpgLQARLM--SQALRKLTG 186
Cdd:cd19513 80 NGEDVLDNvayarayNTDHQMQLLIQASAMMAESRYALLIVDSATALY-RTDYSGR-GE----LSARQMhlAKFLRMLQR 153
|
170 180 190
....*....|....*....|....*....|....*.
gi 1735425040 187 TIKRTNCTVIFINQIRMKI--GVMF-GNPETTTGGN 219
Cdd:cd19513 154 LADEFGVAVVITNQVVAQVdgAAMFaGDPKKPIGGN 189
|
|
| AAA_25 |
pfam13481 |
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins. |
62-198 |
9.79e-07 |
|
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins.
Pssm-ID: 463892 [Multi-domain] Cd Length: 193 Bit Score: 47.38 E-value: 9.79e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 62 LPRGRVIEIYGPESSGKTTLTLQVVAEM-----------QKLGGTCAFIDAE----------HALDVGYASK---LGVSV 117
Cdd:pfam13481 30 LPAGGLGLLAGAPGTGKTTLALDLAAAVatgkpwlggprVPEQGKVLYVSAEgpadelrrrlRAAGADLDLParlLFLSL 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 118 PELL-ISQPDTGEQAL-----EIADALVRSGSIDLIIIDSVAALVPkaeiegemGDSLPGLQARLMSQALRKLtgtIKRT 191
Cdd:pfam13481 110 VESLpLFFLDRGGPLLdadvdALEAALEEVEDPDLVVIDPLARALG--------GDENSNSDVGRLVKALDRL---ARRT 178
|
....*..
gi 1735425040 192 NCTVIFI 198
Cdd:pfam13481 179 GATVLLV 185
|
|
| DMC1 |
cd19514 |
homologous-pairing protein DMC1; DMC1 has a central role in homologous recombination in ... |
46-221 |
1.92e-06 |
|
homologous-pairing protein DMC1; DMC1 has a central role in homologous recombination in meiosis. It assembles at the sites of programmed DNA double-strand breaks and carries out a search for allelic DNA sequences located on homologous chromatids. It forms octameric rings.
Pssm-ID: 410922 [Multi-domain] Cd Length: 236 Bit Score: 46.97 E-value: 1.92e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 46 VSTGSLGLDIALGvGGLPRGRVIEIYGPESSGKTTL--TLQVVAEM-QKLGGTC---AFIDAEHALD----VGYASKLGV 115
Cdd:cd19514 1 ISTGSTELDKLLG-GGIESMSITEVFGEFRTGKTQLshTLCVTAQLpGSMGGGGgkvAYIDTEGTFRpdriRPIAERFGV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 116 S----VPELLISQPDTGEQALEIADAL----VRSGSIDLIIIDSVAALVpKAEI--EGEMGDSlpglQARLmSQALRKLT 185
Cdd:cd19514 80 DhdavLDNILYARAYTSEHQMELLDYVaakfHEEAVFRLLIIDSIMALF-RVDFsgRGELAER----QQKL-AQMLSRLQ 153
|
170 180 190
....*....|....*....|....*....|....*....
gi 1735425040 186 GTIKRTNCTVIFINQIRMKIG--VMF-GNPETTTGGNAL 221
Cdd:cd19514 154 KISEEYNVAVFITNQVTADPGaaMTFqADPKKPIGGHIL 192
|
|
| PLN03187 |
PLN03187 |
meiotic recombination protein DMC1 homolog; Provisional |
23-221 |
2.78e-06 |
|
meiotic recombination protein DMC1 homolog; Provisional
Pssm-ID: 215620 [Multi-domain] Cd Length: 344 Bit Score: 47.08 E-value: 2.78e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 23 EKQFGKGSIMRLGDGEVEADIQVVSTGSLGLDIALGvGGLPRGRVIEIYGPESSGKTTL--TLQVVAEM-QKLGGTC--- 96
Cdd:PLN03187 85 EKLLNQGFITGSDALLKRKSVVRITTGSQALDELLG-GGIETRCITEAFGEFRSGKTQLahTLCVTTQLpTEMGGGNgkv 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 97 AFIDAEHALD----VGYASKLGVS----VPELLISQPDTGEQ---ALEIADALVRSGSIDLIIIDSVAALVPKAEI-EGE 164
Cdd:PLN03187 164 AYIDTEGTFRpdriVPIAERFGMDadavLDNIIYARAYTYEHqynLLLGLAAKMAEEPFRLLIVDSVIALFRVDFTgRGE 243
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1735425040 165 MGDSlpglQARLmSQALRKLTGTIKRTNCTVIFINQIRMKIG--VMFGNPETTTGGNAL 221
Cdd:PLN03187 244 LAER----QQKL-AQMLSRLTKIAEEFNVAVYMTNQVIADPGggMFISDPKKPAGGHVL 297
|
|
| recomb_RAD51 |
TIGR02239 |
DNA repair protein RAD51; This eukaryotic sequence family consists of RAD51, a protein ... |
41-219 |
7.09e-06 |
|
DNA repair protein RAD51; This eukaryotic sequence family consists of RAD51, a protein involved in DNA homologous recombination and repair. It is similar in sequence the exclusively meiotic recombinase DMC1 (TIGR02238), to archaeal families RadA (TIGR02236) and RadB (TIGR02237), and to bacterial RecA (TIGR02012).
Pssm-ID: 274048 [Multi-domain] Cd Length: 316 Bit Score: 45.87 E-value: 7.09e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 41 ADIQVVSTGSLGLDIALGvGGLPRGRVIEIYGPESSGKTTL------TLQVVAEMQKLGGTCAFIDAEHALD----VGYA 110
Cdd:TIGR02239 73 QEVIQLTTGSKELDKLLG-GGIETGSITEIFGEFRTGKTQLchtlavTCQLPIDQGGGEGKALYIDTEGTFRperlLAIA 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 111 SKLGVSVPELLIS-------QPDTGEQALEIADALVRSGSIDLIIIDSVAALVpKAEIEGEmGDslpgLQARLMSQA--L 181
Cdd:TIGR02239 152 ERYGLNPEDVLDNvayarayNTDHQLQLLQQAAAMMSESRFALLIVDSATALY-RTDFSGR-GE----LSARQMHLArfL 225
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1735425040 182 RKLTGTIKRTNCTVIFINQIRMKI---GVMF-GNPETTTGGN 219
Cdd:TIGR02239 226 RSLQRLADEFGVAVVITNQVVAQVdgaGSMFaGDPKKPIGGN 267
|
|
| PLN03186 |
PLN03186 |
DNA repair protein RAD51 homolog; Provisional |
42-201 |
8.59e-06 |
|
DNA repair protein RAD51 homolog; Provisional
Pssm-ID: 178728 [Multi-domain] Cd Length: 342 Bit Score: 45.49 E-value: 8.59e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 42 DIQVVSTGSLGLDIALGvGGLPRGRVIEIYGPESSGKTTL--TLQVVAEM--QKLGGT--CAFIDAEhaldvgyasklGV 115
Cdd:PLN03186 101 EIIQITTGSRELDKILE-GGIETGSITEIYGEFRTGKTQLchTLCVTCQLplDQGGGEgkAMYIDTE-----------GT 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 116 SVPELLISQPD----TGEQALE-IADA-----------LVRSGSI------DLIIIDSVAALVpKAEIEGEmGDslpgLQ 173
Cdd:PLN03186 169 FRPQRLIQIAErfglNGADVLEnVAYArayntdhqselLLEAASMmaetrfALMIVDSATALY-RTEFSGR-GE----LS 242
|
170 180 190
....*....|....*....|....*....|
gi 1735425040 174 AR--LMSQALRKLTGTIKRTNCTVIFINQI 201
Cdd:PLN03186 243 ARqmHLGKFLRSLQRLADEFGVAVVITNQV 272
|
|
| recomb_DMC1 |
TIGR02238 |
meiotic recombinase Dmc1; This model describes DMC1, a subfamily of a larger family of DNA ... |
45-221 |
5.29e-05 |
|
meiotic recombinase Dmc1; This model describes DMC1, a subfamily of a larger family of DNA repair and recombination proteins. It is eukaryotic only and most closely related to eukaryotic RAD51. It also resembles archaeal RadA (TIGR02236) and RadB (TIGR02237) and bacterial RecA (TIGR02012). It has been characterized for human as a recombinase active only in meiosis.
Pssm-ID: 131292 [Multi-domain] Cd Length: 313 Bit Score: 43.23 E-value: 5.29e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 45 VVSTGSLGLDIALGvGGLPRGRVIEIYGPESSGKTTL--TLQVVA----EMQKLGGTCAFIDAE--------HALDVGYA 110
Cdd:TIGR02238 77 KITTGSQALDGILG-GGIESMSITEVFGEFRCGKTQLshTLCVTAqlprEMGGGNGKVAYIDTEgtfrpdriRAIAERFG 155
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 111 SKLGVSVPELLISQPDTGEQALEIAD---ALVRSGSIDLIIIDSVAALVpKAEIEGEmgDSLPGLQARLmSQALRKLTGT 187
Cdd:TIGR02238 156 VDPDAVLDNILYARAYTSEHQMELLDylaAKFSEEPFRLLIVDSIMALF-RVDFSGR--GELSERQQKL-AQMLSRLNKI 231
|
170 180 190
....*....|....*....|....*....|....*..
gi 1735425040 188 IKRTNCTVIFINQIRMKIG--VMF-GNPETTTGGNAL 221
Cdd:TIGR02238 232 SEEFNVAVFVTNQVQADPGatMTFiADPKKPIGGHVL 268
|
|
| ATPase_2 |
pfam01637 |
ATPase domain predominantly from Archaea; This family contain a conserved P-loop motif that is ... |
67-156 |
6.12e-05 |
|
ATPase domain predominantly from Archaea; This family contain a conserved P-loop motif that is involved in binding ATP. There are eukaryote members as well as archaeal members in this family.
Pssm-ID: 376582 [Multi-domain] Cd Length: 222 Bit Score: 42.69 E-value: 6.12e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 67 VIEIYGPESSGKTTLTLQVVAEMQKLGGTCAFIDA-----EHALDVGYASK-----LGVSVPELLISQPDTGEQALEIA- 135
Cdd:pfam01637 22 IYVIYGPEGCGKTALLRESIENLLDLGYYVIYYDPlrryfISKLDRFEEVRrlaeaLGIAVPKAELEESKLAFLAIELLl 101
|
90 100
....*....|....*....|.
gi 1735425040 136 DALVRSGSIDLIIIDSVAALV 156
Cdd:pfam01637 102 EALKRRGKKIAIIIDEVQQAI 122
|
|
| AAA_24 |
pfam13479 |
AAA domain; This AAA domain is found in a wide variety of presumed phage proteins. |
64-198 |
1.13e-04 |
|
AAA domain; This AAA domain is found in a wide variety of presumed phage proteins.
Pssm-ID: 433243 Cd Length: 199 Bit Score: 41.54 E-value: 1.13e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 64 RGRVIEIYGPESSGKTTLTLQvvaemqkLGGTcAFIDAEHALDVGYASKLGVSVPELliSQPDTGEQALEIADALVRsgS 143
Cdd:pfam13479 1 KKLKILIYGPSGIGKTTFAKT-------LPKP-LFLDTEKGSKALDGDRFPDIVIRD--SWQDFLDAIDELTAAELA--D 68
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1735425040 144 IDLIIIDSVAALV-----------PKAEIEGEMGDSLP-GLQARLMSQALRKLTGTIKrtncTVIFI 198
Cdd:pfam13479 69 YKTIVIDTVDWLErlclayickqnGKGSSIEDGGYGKGyGELGEEFRRLLDALQELGK----NVIFT 131
|
|
| PTZ00035 |
PTZ00035 |
Rad51 protein; Provisional |
46-221 |
1.28e-04 |
|
Rad51 protein; Provisional
Pssm-ID: 185407 [Multi-domain] Cd Length: 337 Bit Score: 41.91 E-value: 1.28e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 46 VSTGSLGLDIALGvGGLPRGRVIEIYGPESSGKTTL--TLQVVA----EMQKLGGTCAFIDAEHALD----VGYASKLGV 115
Cdd:PTZ00035 100 ITTGSTQLDKLLG-GGIETGSITELFGEFRTGKTQLchTLCVTCqlpiEQGGGEGKVLYIDTEGTFRperiVQIAERFGL 178
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 116 SVPELL----ISQPDTGEQALEI---ADALVRSGSIDLIIIDSVAALVpKAEIEGEmGDslpgLQARLM--SQALRKLTG 186
Cdd:PTZ00035 179 DPEDVLdniaYARAYNHEHQMQLlsqAAAKMAEERFALLIVDSATALF-RVDYSGR-GE----LAERQQhlGKFLRALQK 252
|
170 180 190
....*....|....*....|....*....|....*...
gi 1735425040 187 TIKRTNCTVIFINQIRMKIG---VMFGNPETTTGGNAL 221
Cdd:PTZ00035 253 LADEFNVAVVITNQVMADVDgasMFVADPKKPIGGHII 290
|
|
| FlaH |
COG2874 |
Archaellum biogenesis ATPase ArlH/FlaH [Cell motility]; |
46-156 |
1.51e-03 |
|
Archaellum biogenesis ATPase ArlH/FlaH [Cell motility];
Pssm-ID: 442121 Cd Length: 230 Bit Score: 38.27 E-value: 1.51e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 46 VSTGSLGLDIALGvGGLPRGRVIEIYGPESSGKTTLTLQVVAEMQKLGGTCAFIDAEHA----LDVGYASKLGVS----- 116
Cdd:COG2874 3 ISTGNDELDKRLG-GGIPLGSLVLIEGENGTGKSVLSQQFAYGALENGLSVTYISTELTtkefIKQMKSLSYDISdyllr 81
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 1735425040 117 -----VPELLISQPDTGEQALEIADALVRSGSI-----DLIIIDSVAALV 156
Cdd:COG2874 82 grllfLPVHPLGFEWNSKQRKDLLKRLMKYIASnlweaDVIIIDSLSALL 131
|
|
| Rad51D |
cd19489 |
RAD51D recombinase; RAD51D recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
60-156 |
1.84e-03 |
|
RAD51D recombinase; RAD51D recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51D, together with the other RAD51 paralogs, RAD51B, RAD51C, XRCC3, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410897 [Multi-domain] Cd Length: 209 Bit Score: 38.00 E-value: 1.84e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 60 GGLPRGRVIEIYGPESSGKTTLTLQVVAEM-QKLGGTCAFIDAEHALdvgYASKLGvsvpELLISQPDTGEQALEIADAL 138
Cdd:cd19489 2 GGLRTGEITELVGESSSGKTQLCLTAAANVaSRSGQNVLYIDTKSSF---SARRLA----QILKSRAQDAEEIDKALQRI 74
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 1735425040 139 --VR-------------------------SGSIDLIIIDSVAALV 156
Cdd:cd19489 75 rvVRvfdpyelldlleelrntlsqqqenlYSRLKLVIIDSLSALI 119
|
|
| Grc3 |
COG1341 |
Polynucleotide 5'-kinase, involved in rRNA processing [Translation, ribosomal structure and ... |
63-108 |
3.19e-03 |
|
Polynucleotide 5'-kinase, involved in rRNA processing [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440952 Cd Length: 353 Bit Score: 37.69 E-value: 3.19e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 1735425040 63 PRGRVIEIYGPESSGKTTLTLQVVAEMQKLGGTCAFIDAehalDVG 108
Cdd:COG1341 33 SGPGRIMVLGPVDSGKSTLTTLLANKLLAEGLKVAIIDA----DVG 74
|
|
| PRK06067 |
PRK06067 |
flagellar accessory protein FlaH; Validated |
40-162 |
3.55e-03 |
|
flagellar accessory protein FlaH; Validated
Pssm-ID: 180381 Cd Length: 234 Bit Score: 37.26 E-value: 3.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 40 EADIQVVSTGSLGLDIALGvGGLPRGRVIEIYGPESSGKTTLTLQVVAEMQKLGGTCAFIDAEH------------ALDV 107
Cdd:PRK06067 1 EGKKEIISTGNEELDRKLG-GGIPFPSLILIEGDHGTGKSVLSQQFVYGALKQGKKVYVITTENtsksylkqmesvKIDI 79
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1735425040 108 ------GYASKLGVSVPELLISqPDTGEQALEIADALVRSGSIDLIIIDSVAALVPKAEIE 162
Cdd:PRK06067 80 sdfflwGYLRIFPLNTEGFEWN-STLANKLLELIIEFIKSKREDVIIIDSLTIFATYAEED 139
|
|
| RecA-like_NVL_r2-like |
cd19530 |
second of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL ... |
56-196 |
6.82e-03 |
|
second of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL exists in two forms with N-terminal extensions of different lengths in mammalian cells. NVL has two alternatively spliced isoforms, a short form, NVL1, and a long form, NVL2. NVL2, the major species, is mainly present in the nucleolus, whereas NVL1 is nucleoplasmic. Each has an N-terminal domain, followed by two tandem ATPase domains; this subfamily includes the first of the two ATPase domains. NVL2 is involved in the biogenesis of the 60S ribosome subunit by associating specifically with ribosome protein L5 and modulating the function of DOB1. NVL2 is also required for telomerase assembly and the regulation of telomerase activity, and is involved in pre-rRNA processing. The role of NVL1 is unclear. This RecA-like_NVL_r1-like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410938 [Multi-domain] Cd Length: 161 Bit Score: 35.93 E-value: 6.82e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735425040 56 ALGVGgLPRGrvIEIYGPESSGKTTLTLQVVAEMQklggtcafidaehaldvgyASKLGVSVPELLISQPDTGEQALEIA 135
Cdd:cd19530 24 ALGID-LPTG--VLLYGPPGCGKTLLAKAVANESG-------------------ANFISVKGPELLNKYVGESERAVRQV 81
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1735425040 136 DALVRSGSIDLIIIDSVAALVPKaeiegeMGDSLPGLQARLMSQALRKLTGTIKRTNCTVI 196
Cdd:cd19530 82 FQRARASAPCVIFFDEVDALVPK------RGDGGSWASERVVNQLLTEMDGLEERSNVFVI 136
|
|
| |
