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Conserved domains on  [gi|2340759888|gb|UZT99230|]
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(2Fe-2S)-binding protein [Chryseobacterium fluminis]

Protein Classification

(2Fe-2S)-binding protein( domain architecture ID 11449880)

(2Fe-2S)-binding protein is the small subunit of a dehydrogenase or oxidoreductase enzyme complex such as carbon monoxide dehydrogenase and isoquinoline 1-oxidoreductase; contains a a 2Fe-2S ferredoxin-type domain which binds 2Fe-2S clusters

Gene Ontology:  GO:0046872|GO:0051536|GO:0051537
PubMed:  11734195
SCOP:  3000113

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CutS COG2080
Aldehyde, CO, or xanthine dehydrogenase, Fe-S subunit, CoxS/CutS family [Energy production and ...
 6-154 1.05e-86

Aldehyde, CO, or xanthine dehydrogenase, Fe-S subunit, CoxS/CutS family [Energy production and conversion]; Aldehyde, CO, or xanthine dehydrogenase, Fe-S subunit, CoxS/CutS family is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


:

Pssm-ID: 441683 [Multi-domain]  Cd Length: 155  Bit Score: 250.39  E-value: 1.05e-86
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2340759888   6 KQSITLKVNGKEHHLEVLPWVSLLDALRENLHFTGTKKGCDHGQCGACTVLIDGKRVLSCLSLCVMKTDAEITTIEGISD 85
Cdd:COG2080     1 MMMITLTVNGKPVEVDVDPDTPLLDVLRDDLGLTGTKFGCGHGQCGACTVLVDGKAVRSCLTLAVQADGKEITTIEGLAE 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2340759888  86 GENLHPVQQAFIDHDAFQCGYCTPGQICSAVGLLSEGKAKTREEVQDLMSGNLCRCGANRGIINAVMSV 154
Cdd:COG2080    81 DGELHPLQQAFIEHGALQCGYCTPGMIMAAVALLDENPNPTEEEIREALSGNLCRCTGYVRIVRAVKRA 149
 
Name Accession Description Interval E-value
CutS COG2080
Aldehyde, CO, or xanthine dehydrogenase, Fe-S subunit, CoxS/CutS family [Energy production and ...
 6-154 1.05e-86

Aldehyde, CO, or xanthine dehydrogenase, Fe-S subunit, CoxS/CutS family [Energy production and conversion]; Aldehyde, CO, or xanthine dehydrogenase, Fe-S subunit, CoxS/CutS family is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 441683 [Multi-domain]  Cd Length: 155  Bit Score: 250.39  E-value: 1.05e-86
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2340759888   6 KQSITLKVNGKEHHLEVLPWVSLLDALRENLHFTGTKKGCDHGQCGACTVLIDGKRVLSCLSLCVMKTDAEITTIEGISD 85
Cdd:COG2080     1 MMMITLTVNGKPVEVDVDPDTPLLDVLRDDLGLTGTKFGCGHGQCGACTVLVDGKAVRSCLTLAVQADGKEITTIEGLAE 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2340759888  86 GENLHPVQQAFIDHDAFQCGYCTPGQICSAVGLLSEGKAKTREEVQDLMSGNLCRCGANRGIINAVMSV 154
Cdd:COG2080    81 DGELHPLQQAFIEHGALQCGYCTPGMIMAAVALLDENPNPTEEEIREALSGNLCRCTGYVRIVRAVKRA 149
PRK11433 PRK11433
aldehyde oxidoreductase 2Fe-2S subunit; Provisional
 9-154 2.46e-73

aldehyde oxidoreductase 2Fe-2S subunit; Provisional


Pssm-ID: 236910 [Multi-domain]  Cd Length: 217  Bit Score: 218.87  E-value: 2.46e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2340759888   9 ITLKVNGKEHHLEVLPWVSLLDALRENLHFTGTKKGCDHGQCGACTVLIDGKRVLSCLSLCVMKTDAEITTIEGISDGEN 88
Cdd:PRK11433   52 VTLKVNGKTEQLEVDTRTTLLDALREHLHLTGTKKGCDHGQCGACTVLVNGRRLNACLTLAVMHQGAEITTIEGLGSPDN 131

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2340759888  89 LHPVQQAFIDHDAFQCGYCTPGQICSAVGLLSEGKAK---------------TREEVQDLMSGNLCRCGANRGIINAVMS 153
Cdd:PRK11433  132 LHPMQAAFVKHDGFQCGYCTPGQICSSVAVLKEIKDGipshvtvdltaapelTADEIRERMSGNICRCGAYSNILEAIED 211


                  .
gi 2340759888 154 V 154
Cdd:PRK11433  212 V 212
glyceraldDH_gamma NF041020
glyceraldehyde dehydrogenase subunit gamma;
6-156 4.29e-54

glyceraldehyde dehydrogenase subunit gamma;


Pssm-ID: 468949 [Multi-domain]  Cd Length: 162  Bit Score: 168.05  E-value: 4.29e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2340759888   6 KQSITLKVNGKEHHLEVLPWVSLLDALRENLHFTGTKKGCDHGQCGACTVLIDGKRVLSCLSLCVMKTDAEITTIEGISD 85
Cdd:NF041020    8 KVKIRVKVNGVWYEAEVEPRKLLVHFLRDDLGFTGTHVGCDTSTCGACTVIMNGKSVKSCTVLAVQADGAEITTIEGLSK 87

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2340759888  86 GENLHPVQQAFIDHDAFQCGYCTPGQICSAVGLLSEGKAKTREEVQDLMSGNLCRCGANRGIINAVMSVKQ 156
Cdd:NF041020   88 DGKLHPIQEAFWENHALQCGYCTPGMIMQAYFLLKENPNPTEEEIRDGIHGNLCRCTGYQNIVKAVKEASQ 158
pucE TIGR03198
xanthine dehydrogenase E subunit; This gene has been characterized in B. subtilis as the ...
 6-151 6.16e-43

xanthine dehydrogenase E subunit; This gene has been characterized in B. subtilis as the Iron-sulfur cluster binding-subunit of xanthine dehydrogenase (pucE), acting in conjunction with pucC, the FAD-binding subunit and pucD, the molybdopterin binding subunit. The more common XDH complex (GenProp0640) includes the xdhA gene as the Fe-S cluster binding component.


Pssm-ID: 132242 [Multi-domain]  Cd Length: 151  Bit Score: 139.60  E-value: 6.16e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2340759888   6 KQSITLKVNGKEHHLEVLPWVSLLDALRENLHFTGTKKGCDHGQCGACTVLIDGKRVLSCLSLCVMKTDAEITTIEGISD 85
Cdd:TIGR03198   1 KEQFRFTVNGQAWEVAAVPTTRLSDLLRKELQLTGTKVSCGIGRCGACSVLIDGKLANACLTMAYQADGHEITTIEGIAE 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2340759888  86 GEnLHPVQQAFIDHDAFQCGYCTPGQICSAVGLLSEGKAKTREEVQDLMSGNLCRCGANRGIINAV 151
Cdd:TIGR03198  81 NE-LDPCQTAFLEEGGFQCGYCTPGMVVALKALFRETPQPSDEDMEEGLSGNLCRCTGYGGIIRSA 145
Fer2_2 pfam01799
[2Fe-2S] binding domain;
79-151 1.48e-34

[2Fe-2S] binding domain;


Pssm-ID: 460336 [Multi-domain]  Cd Length: 73  Bit Score: 115.61  E-value: 1.48e-34
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2340759888  79 TIEGISDGENlHPVQQAFIDHDAFQCGYCTPGQICSAVGLLSEGKAKTRE-EVQDLMSGNLCRCGANRGIINAV 151
Cdd:pfam01799   1 TIEGLAESGG-EPVQQAFAEAGAVQCGYCTPGMIMSAYALLERNPPPPTEaEIREALSGNLCRCTGYRRIVDAV 73
fer2 cd00207
2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in ...
 9-78 5.67e-07

2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis and ferredoxins, which participate in redox chains (from bacteria to mammals). Fold is ismilar to thioredoxin.


Pssm-ID: 238126 [Multi-domain]  Cd Length: 84  Bit Score: 45.08  E-value: 5.67e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2340759888   9 ITLKVNGKEHHLEVLPWVSLLDALRENLHftGTKKGCDHGQCGACTVLID------------------GKRVLSClsLCV 70
Cdd:cd00207     1 VTINVPGSGVEVEVPEGETLLDAAREAGI--DIPYSCRAGACGTCKVEVVegevdqsdpslldeeeaeGGYVLAC--QTR 76


                  ....*...
gi 2340759888  71 MKTDAEIT 78
Cdd:cd00207    77 VTDGLVIE 84
 
Name Accession Description Interval E-value
CutS COG2080
Aldehyde, CO, or xanthine dehydrogenase, Fe-S subunit, CoxS/CutS family [Energy production and ...
 6-154 1.05e-86

Aldehyde, CO, or xanthine dehydrogenase, Fe-S subunit, CoxS/CutS family [Energy production and conversion]; Aldehyde, CO, or xanthine dehydrogenase, Fe-S subunit, CoxS/CutS family is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 441683 [Multi-domain]  Cd Length: 155  Bit Score: 250.39  E-value: 1.05e-86
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2340759888   6 KQSITLKVNGKEHHLEVLPWVSLLDALRENLHFTGTKKGCDHGQCGACTVLIDGKRVLSCLSLCVMKTDAEITTIEGISD 85
Cdd:COG2080     1 MMMITLTVNGKPVEVDVDPDTPLLDVLRDDLGLTGTKFGCGHGQCGACTVLVDGKAVRSCLTLAVQADGKEITTIEGLAE 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2340759888  86 GENLHPVQQAFIDHDAFQCGYCTPGQICSAVGLLSEGKAKTREEVQDLMSGNLCRCGANRGIINAVMSV 154
Cdd:COG2080    81 DGELHPLQQAFIEHGALQCGYCTPGMIMAAVALLDENPNPTEEEIREALSGNLCRCTGYVRIVRAVKRA 149
PRK11433 PRK11433
aldehyde oxidoreductase 2Fe-2S subunit; Provisional
 9-154 2.46e-73

aldehyde oxidoreductase 2Fe-2S subunit; Provisional


Pssm-ID: 236910 [Multi-domain]  Cd Length: 217  Bit Score: 218.87  E-value: 2.46e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2340759888   9 ITLKVNGKEHHLEVLPWVSLLDALRENLHFTGTKKGCDHGQCGACTVLIDGKRVLSCLSLCVMKTDAEITTIEGISDGEN 88
Cdd:PRK11433   52 VTLKVNGKTEQLEVDTRTTLLDALREHLHLTGTKKGCDHGQCGACTVLVNGRRLNACLTLAVMHQGAEITTIEGLGSPDN 131

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2340759888  89 LHPVQQAFIDHDAFQCGYCTPGQICSAVGLLSEGKAK---------------TREEVQDLMSGNLCRCGANRGIINAVMS 153
Cdd:PRK11433  132 LHPMQAAFVKHDGFQCGYCTPGQICSSVAVLKEIKDGipshvtvdltaapelTADEIRERMSGNICRCGAYSNILEAIED 211


                  .
gi 2340759888 154 V 154
Cdd:PRK11433  212 V 212
glyceraldDH_gamma NF041020
glyceraldehyde dehydrogenase subunit gamma;
6-156 4.29e-54

glyceraldehyde dehydrogenase subunit gamma;


Pssm-ID: 468949 [Multi-domain]  Cd Length: 162  Bit Score: 168.05  E-value: 4.29e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2340759888   6 KQSITLKVNGKEHHLEVLPWVSLLDALRENLHFTGTKKGCDHGQCGACTVLIDGKRVLSCLSLCVMKTDAEITTIEGISD 85
Cdd:NF041020    8 KVKIRVKVNGVWYEAEVEPRKLLVHFLRDDLGFTGTHVGCDTSTCGACTVIMNGKSVKSCTVLAVQADGAEITTIEGLSK 87

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2340759888  86 GENLHPVQQAFIDHDAFQCGYCTPGQICSAVGLLSEGKAKTREEVQDLMSGNLCRCGANRGIINAVMSVKQ 156
Cdd:NF041020   88 DGKLHPIQEAFWENHALQCGYCTPGMIMQAYFLLKENPNPTEEEIRDGIHGNLCRCTGYQNIVKAVKEASQ 158
XdhA COG4630
Xanthine dehydrogenase, Fe-S cluster and FAD-binding subunit XdhA [Nucleotide transport and ...
 9-154 3.14e-45

Xanthine dehydrogenase, Fe-S cluster and FAD-binding subunit XdhA [Nucleotide transport and metabolism];


Pssm-ID: 443668 [Multi-domain]  Cd Length: 476  Bit Score: 154.14  E-value: 3.14e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2340759888   9 ITLKVNGKEHHLEVL-PWVSLLDALRENLHFTGTKKGCDHGQCGACTVLI----DGKRVL----SCLSLCVMKTDAEITT 79
Cdd:COG4630     1 IRFLLNGELVELSDVpPTTTLLDWLREDRGLTGTKEGCAEGDCGACTVVVgeldDGGLRYravnACILFLPQLDGKALVT 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2340759888  80 IEGISDGE-NLHPVQQAFIDHDAFQCGYCTPGQICSAVGLLSEGKAKTREEVQDLMSGNLCRCGANRGIINAVMSV 154
Cdd:COG4630    81 VEGLAGPDgALHPVQQAMVDHHGSQCGFCTPGFVMSLFALYERGPAPDRADIEDALSGNLCRCTGYRPIIDAARAM 156
pucE TIGR03198
xanthine dehydrogenase E subunit; This gene has been characterized in B. subtilis as the ...
 6-151 6.16e-43

xanthine dehydrogenase E subunit; This gene has been characterized in B. subtilis as the Iron-sulfur cluster binding-subunit of xanthine dehydrogenase (pucE), acting in conjunction with pucC, the FAD-binding subunit and pucD, the molybdopterin binding subunit. The more common XDH complex (GenProp0640) includes the xdhA gene as the Fe-S cluster binding component.


Pssm-ID: 132242 [Multi-domain]  Cd Length: 151  Bit Score: 139.60  E-value: 6.16e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2340759888   6 KQSITLKVNGKEHHLEVLPWVSLLDALRENLHFTGTKKGCDHGQCGACTVLIDGKRVLSCLSLCVMKTDAEITTIEGISD 85
Cdd:TIGR03198   1 KEQFRFTVNGQAWEVAAVPTTRLSDLLRKELQLTGTKVSCGIGRCGACSVLIDGKLANACLTMAYQADGHEITTIEGIAE 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2340759888  86 GEnLHPVQQAFIDHDAFQCGYCTPGQICSAVGLLSEGKAKTREEVQDLMSGNLCRCGANRGIINAV 151
Cdd:TIGR03198  81 NE-LDPCQTAFLEEGGFQCGYCTPGMVVALKALFRETPQPSDEDMEEGLSGNLCRCTGYGGIIRSA 145
4hydroxCoAred TIGR03193
4-hydroxybenzoyl-CoA reductase, gamma subunit; 4-hydroxybenzoyl-CoA reductase converts ...
 9-151 1.82e-40

4-hydroxybenzoyl-CoA reductase, gamma subunit; 4-hydroxybenzoyl-CoA reductase converts 4-hydroxybenzoyl-CoA to benzoyl-CoA, a common intermediate in the degradation of aromatic compounds. This protein family represents the gamma chain of this three-subunit enzyme.


Pssm-ID: 132237 [Multi-domain]  Cd Length: 148  Bit Score: 133.08  E-value: 1.82e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2340759888   9 ITLKVNGKEHHLEVLPWVSLLDALRENLHFTGTKKGCDHGQCGACTVLIDGKRVLSCLSLCVMKTDAEITTIEGISDGEN 88
Cdd:TIGR03193   2 LRLTVNGRWREDAVADNMLLVDYLRDTVGLTGTKQGCDGGECGACTVLVDGRPRLACSTLAHRVAGRKVETVEGLATNGR 81

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2340759888  89 LHPVQQAFIDHDAFQCGYCTPGQICSAVGLLSEGKAKTREEVQDLMSGNLCRCGANRGIINAV 151
Cdd:TIGR03193  82 LSRLQQAFHERLGTQCGFCTPGMIMAAEALLRRNPSPSRDEIRAALAGNLCRCTGYVKIIESV 144
PRK09908 PRK09908
xanthine dehydrogenase iron sulfur-binding subunit XdhC;
8-151 4.94e-37

xanthine dehydrogenase iron sulfur-binding subunit XdhC;


Pssm-ID: 182139 [Multi-domain]  Cd Length: 159  Bit Score: 124.64  E-value: 4.94e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2340759888   8 SITLKVNGKEHHLEVLPWVSLLDALRENlHFTGTKKGCDHGQCGACTVLIDGKRVLSCLSLCVMKTDAEITTIEGISDGE 87
Cdd:PRK09908    8 TIECTINGMPFQLHAAPGTPLSELLREQ-GLLSVKQGCCVGECGACTVLVDGTAIDSCLYLAAWAEGKEIRTLEGEAKGG 86

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2340759888  88 NLHPVQQAFIDHDAFQCGYCTPGQICSAVGLLSEGKAK--TREEVQDLMSGNLCRCGANRGIINAV 151
Cdd:PRK09908   87 KLSHVQQAYAKSGAVQCGFCTPGLIMATTAMLAKPREKplTITEIRRGLAGNLCRCTGYQMIVNTV 152
xanthine_xdhA TIGR02963
xanthine dehydrogenase, small subunit; Members of this protein family are the small subunit ...
 9-150 5.25e-36

xanthine dehydrogenase, small subunit; Members of this protein family are the small subunit (or, in eukaryotes, the N-terminal domain) of xanthine dehydrogenase, an enzyme of purine catabolism via urate. The small subunit contains both an FAD and a 2Fe-2S cofactor. Aldehyde oxidase (retinal oxidase) appears to have arisen as a neofunctionalization among xanthine dehydrogenases in eukaryotes and [Purines, pyrimidines, nucleosides, and nucleotides, Other]


Pssm-ID: 274365 [Multi-domain]  Cd Length: 467  Bit Score: 129.32  E-value: 5.25e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2340759888   9 ITLKVNGKEHHLE-VLPWVSLLDALRENLHFTGTKKGCDHGQCGACTVLI----DGKRVL-----SCLS-LCVMKTDAeI 77
Cdd:TIGR02963   1 IRFFLNGETVTLSdVDPTRTLLDYLREDAGLTGTKEGCAEGDCGACTVVVgelvDGGKLRyrsvnACIQfLPSLDGKA-V 79

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2340759888  78 TTIEGI--SDGEnLHPVQQAFIDHDAFQCGYCTPGQICSAVGLLSEGKAKTREEVQDLMSGNLCRCGANRGIINA 150
Cdd:TIGR02963  80 VTVEDLrqPDGR-LHPVQQAMVECHGSQCGFCTPGFVMSLYALYKNSPAPSRADIEDALQGNLCRCTGYRPILDA 153
Fer2_2 pfam01799
[2Fe-2S] binding domain;
79-151 1.48e-34

[2Fe-2S] binding domain;


Pssm-ID: 460336 [Multi-domain]  Cd Length: 73  Bit Score: 115.61  E-value: 1.48e-34
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2340759888  79 TIEGISDGENlHPVQQAFIDHDAFQCGYCTPGQICSAVGLLSEGKAKTRE-EVQDLMSGNLCRCGANRGIINAV 151
Cdd:pfam01799   1 TIEGLAESGG-EPVQQAFAEAGAVQCGYCTPGMIMSAYALLERNPPPPTEaEIREALSGNLCRCTGYRRIVDAV 73
Se_dep_XDH TIGR03311
selenium-dependent xanthine dehydrogenase; Members of this protein resemble conventional ...
 13-151 1.68e-32

selenium-dependent xanthine dehydrogenase; Members of this protein resemble conventional xanthine dehydrogenase enzymes, which depend on molybdenum cofactor - molybdopterin bound to molybdate with two sulfur atoms as ligands. But all members of this family occur in species that contain markers for the biosynthesis of enzymes with a selenium-containing form of molybdenum cofactor. The member of this family from Enterococcus faecalis has been shown to act as a xanthine dehydrogenenase, and its activity if dependent on SelD (selenophosphate synthase), selenium, and molybdenum. [Purines, pyrimidines, nucleosides, and nucleotides, Other]


Pssm-ID: 132354 [Multi-domain]  Cd Length: 848  Bit Score: 121.49  E-value: 1.68e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2340759888  13 VNGKEhhLEVLPWVSLLDALRENLHFTGTKKGCDHGQCGACTVLIDGKRVLSCLSLCVMKTDAEITTIEGISDGENlHPV 92
Cdd:TIGR03311   5 VNGRE--VDVNEEKKLLEFLREDLRLTGVKNGCGEGACGACTVIVNGKAVRACRFTTAKLAGKEITTVEGLTEREK-DVY 81

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2340759888  93 QQAFIDHDAFQCGYCTPGQICSAVGLLSEGKAKTREEVQDLMSGNLCRCGANRGIINAV 151
Cdd:TIGR03311  82 AWAFAKAGAVQCGFCIPGMVISAKALLDKNPNPTEAEIKKALKGNICRCTGYVKIIKAV 140
mam_aldehyde_ox TIGR02969
aldehyde oxidase; Members of this family are mammalian aldehyde oxidase (EC 1.2.3.1) isozymes, ...
 13-150 2.65e-28

aldehyde oxidase; Members of this family are mammalian aldehyde oxidase (EC 1.2.3.1) isozymes, closely related to xanthine dehydrogenase/oxidase.


Pssm-ID: 132014 [Multi-domain]  Cd Length: 1330  Bit Score: 109.33  E-value: 2.65e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2340759888   13 VNGKEH-HLEVLPWVSLLDALRENLHFTGTKKGCDHGQCGACTVLID-----GKRVL-----SCLSLCVMKTDAEITTIE 81
Cdd:TIGR02969    7 VNGRKVvEKNVDPETMLLPYLRKKLRLTGTKYGCGGGGCGACTVMISrynpsTKSIRhhpvnACLTPICSLYGAAVTTVE 86

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2340759888   82 GI-SDGENLHPVQQAFIDHDAFQCGYCTPGQICSAVGLLSEGKAKTREEVQDLMSGNLCRCGANRGIINA 150
Cdd:TIGR02969   87 GIgSTRTRLHPVQERIAKCHGTQCGFCTPGMVMSMYALLRNHPEPTLDQLTDALGGNLCRCTGYRPIIDA 156
PLN02906 PLN02906
xanthine dehydrogenase
 27-150 3.65e-28

xanthine dehydrogenase


Pssm-ID: 215491 [Multi-domain]  Cd Length: 1319  Bit Score: 109.02  E-value: 3.65e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2340759888   27 SLLDALREnLHFTGTKKGCDHGQCGACTVLI-----DGKRVL-----SCLSlCVMKTDA-EITTIEGISDGE-NLHPVQQ 94
Cdd:PLN02906     3 TLLEYLRD-LGLTGTKLGCGEGGCGACTVMVshydrKTGKCVhyavnACLA-PLYSVEGmHVITVEGIGNRRdGLHPVQE 80

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2340759888   95 AFIDHDAFQCGYCTPGQICSAVGLL-SEGKAKTREEVQDLMSGNLCRCGANRGIINA 150
Cdd:PLN02906    81 ALASMHGSQCGFCTPGFIMSMYALLrSSKTPPTEEQIEECLAGNLCRCTGYRPILDA 137
PLN00192 PLN00192
aldehyde oxidase
 4-153 6.08e-26

aldehyde oxidase


Pssm-ID: 215096 [Multi-domain]  Cd Length: 1344  Bit Score: 102.87  E-value: 6.08e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2340759888    4 TGKQSITLKVNGKEHHLE-VLPWVSLLDALRENLHFTGTKKGCDHGQCGACTVLI----------DGKRVLSCLSLCVMK 72
Cdd:PLN00192     1 SSNMSLVFAVNGERFELSsVDPSTTLLEFLRTQTPFKSVKLGCGEGGCGACVVLLskydpvldqvEDFTVSSCLTLLCSV 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2340759888   73 TDAEITTIEGISDGEN-LHPVQQAFIDHDAFQCGYCTPGQICSAVGLLSEGKAKTRE------------EVQDLMSGNLC 139
Cdd:PLN00192    81 NGCSITTSEGLGNSKDgFHPIHKRFAGFHASQCGFCTPGMCISLFSALVNADKTDRPeppsgfskltvvEAEKAVSGNLC 160

                          170
                   ....*....|....
gi 2340759888  140 RCGANRGIINAVMS 153
Cdd:PLN00192   161 RCTGYRPIVDACKS 174
PRK09800 PRK09800
putative hypoxanthine oxidase; Provisional
 8-140 2.14e-10

putative hypoxanthine oxidase; Provisional


Pssm-ID: 182084 [Multi-domain]  Cd Length: 956  Bit Score: 57.92  E-value: 2.14e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2340759888   8 SITLKVNGKEHHLEVLPWvsllDALRENLHFTG--TKKGCDHGQ--CGACTVLIDGKRVLSCLSLCVMKTDAEITTIEGI 83
Cdd:PRK09800    2 IIHFTLNGAPQELTVNPG----ENVQKLLFNMGmhSVRNSDDGFgfAGSDAIIFNGNIVNASLLIAAQLEKADIRTAESL 77

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2340759888  84 SDGENLHPVQQAFIDHDAFQCGYCTPGQICSAVGLLSEGKAKTREEVQDLMSGNLCR 140
Cdd:PRK09800   78 GKWNELSLVQQAMVDVGVVQSGYNDPAAALIITDLLDRIAAPTREEIDDALSGLFSR 134
fer2 cd00207
2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in ...
 9-78 5.67e-07

2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis and ferredoxins, which participate in redox chains (from bacteria to mammals). Fold is ismilar to thioredoxin.


Pssm-ID: 238126 [Multi-domain]  Cd Length: 84  Bit Score: 45.08  E-value: 5.67e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2340759888   9 ITLKVNGKEHHLEVLPWVSLLDALRENLHftGTKKGCDHGQCGACTVLID------------------GKRVLSClsLCV 70
Cdd:cd00207     1 VTINVPGSGVEVEVPEGETLLDAAREAGI--DIPYSCRAGACGTCKVEVVegevdqsdpslldeeeaeGGYVLAC--QTR 76


                  ....*...
gi 2340759888  71 MKTDAEIT 78
Cdd:cd00207    77 VTDGLVIE 84
Fer2_3 pfam13085
2Fe-2S iron-sulfur cluster binding domain; The 2Fe-2S ferredoxin family have a general core ...
 17-102 7.38e-06

2Fe-2S iron-sulfur cluster binding domain; The 2Fe-2S ferredoxin family have a general core structure consisting of beta(2)-alpha-beta(2) which abeta-grasp type fold. The domain is around one hundred amino acids with four conserved cysteine residues to which the 2Fe-2S cluster is ligated.


Pssm-ID: 432963 [Multi-domain]  Cd Length: 107  Bit Score: 42.61  E-value: 7.38e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2340759888  17 EHHLEVLPWVSLLDAL---REN----LHFtgtKKGCDHGQCGACTVLIDGKRVLSCLSLcVMKTDAEITTIEGISDgenl 89
Cdd:pfam13085  20 EYEVPYEEGMTVLDALnkiKEEqdptLAF---RRSCREGICGSCAMNINGKPRLACKTL-IDDLLGQDITLEPLPG---- 91

                          90
                  ....*....|....
gi 2340759888  90 HPVQQAFI-DHDAF 102
Cdd:pfam13085  92 FPVIRDLVvDRSAF 105
Fer2 pfam00111
2Fe-2S iron-sulfur cluster binding domain;
11-67 6.99e-05

2Fe-2S iron-sulfur cluster binding domain;


Pssm-ID: 395061 [Multi-domain]  Cd Length: 77  Bit Score: 39.43  E-value: 6.99e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2340759888  11 LKVNGKEHHLEVLPWVS-LLDALRENLhfTGTKKGCDHGQCGACTVLIDGKRVLSCLS 67
Cdd:pfam00111   1 VTINGKGVTIEVPDGETtLLDAAEEAG--IDIPYSCRGGGCGTCAVKVLEGEDQSDQS 56
PRK12576 PRK12576
succinate dehydrogenase/fumarate reductase iron-sulfur subunit;
16-102 7.20e-05

succinate dehydrogenase/fumarate reductase iron-sulfur subunit;


Pssm-ID: 237143 [Multi-domain]  Cd Length: 279  Bit Score: 41.66  E-value: 7.20e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2340759888  16 KEHHLEVLPWVSLLDALR----ENLHFTGTKKGCDHGQCGACTVLIDGKRVLSCLSLC--VMKTDAEITTIEGIsdgENL 89
Cdd:PRK12576   25 QEYKVKVDRFTQVTEALRrikeEQDPTLSYRASCHMAVCGSCGMKINGEPRLACKTLVldVAKKYNSVITIEPM---DYF 101

                          90
                  ....*....|...
gi 2340759888  90 HPVQQAFIDHDAF 102
Cdd:PRK12576  102 KVVKDLIVDFDEF 114
PRK06259 PRK06259
succinate dehydrogenase/fumarate reductase iron-sulfur subunit; Provisional
 16-65 1.05e-03

succinate dehydrogenase/fumarate reductase iron-sulfur subunit; Provisional


Pssm-ID: 235756 [Multi-domain]  Cd Length: 486  Bit Score: 38.45  E-value: 1.05e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2340759888  16 KEHHLEVLPWVSLLDALR-------ENLHFtgtKKGCDHGQCGACTVLIDGKRVLSC 65
Cdd:PRK06259   21 ESYEVPVKEGMTVLDALEyinktydANIAF---RSSCRAGQCGSCAVTINGEPVLAC 74
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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