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Conserved domains on  [gi|2324333523|gb|UYX79567|]
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DNA gyrase subunit A, partial [Klebsiella variicola]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK05560 super family cl35335
DNA gyrase subunit A; Validated
 1-99 5.33e-83

DNA gyrase subunit A; Validated


The actual alignment was detected with superfamily member PRK05560:

Pssm-ID: 235502 [Multi-domain]  Cd Length: 805  Bit Score: 256.88  E-value: 5.33e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2324333523   1 MAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTERIPDVMPTKIPNLLVNGA 80
Cdd:PRK05560   89 MAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARMSKIAHELLADIDKETVDFVPNYDGSEQEPTVLPARFPNLLVNGS 168

                          90
                  ....*....|....*....
gi 2324333523  81 SGIAVGMATNIPPHNLTEV 99
Cdd:PRK05560  169 SGIAVGMATNIPPHNLGEV 187
 
Name Accession Description Interval E-value
PRK05560 PRK05560
DNA gyrase subunit A; Validated
 1-99 5.33e-83

DNA gyrase subunit A; Validated


Pssm-ID: 235502 [Multi-domain]  Cd Length: 805  Bit Score: 256.88  E-value: 5.33e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2324333523   1 MAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTERIPDVMPTKIPNLLVNGA 80
Cdd:PRK05560   89 MAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARMSKIAHELLADIDKETVDFVPNYDGSEQEPTVLPARFPNLLVNGS 168

                          90
                  ....*....|....*....
gi 2324333523  81 SGIAVGMATNIPPHNLTEV 99
Cdd:PRK05560  169 SGIAVGMATNIPPHNLGEV 187
GyrA COG0188
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair];
1-99 1.02e-80

DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair];


Pssm-ID: 439958 [Multi-domain]  Cd Length: 804  Bit Score: 250.73  E-value: 1.02e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2324333523   1 MAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTERIPDVMPTKIPNLLVNGA 80
Cdd:COG0188    94 MAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARLAKIAEELLADIDKDTVDFVPNYDGSEQEPTVLPARFPNLLVNGS 173

                          90
                  ....*....|....*....
gi 2324333523  81 SGIAVGMATNIPPHNLTEV 99
Cdd:COG0188   174 SGIAVGMATNIPPHNLGEV 192
gyrA TIGR01063
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). ...
 1-99 4.69e-70

DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). Two apparently independently arising families, one in the Proteobacteria and one in Gram-positive lineages, are both designated toposisomerase IV. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273423 [Multi-domain]  Cd Length: 800  Bit Score: 222.57  E-value: 4.69e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2324333523   1 MAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTERIPDVMPTKIPNLLVNGA 80
Cdd:TIGR01063  85 MAQDFSLRYPLVDGQGNFGSIDGDPPAAMRYTEARLTKIAEELLRDIDKETVDFVPNYDGSEQEPTVLPSRFPNLLVNGS 164

                          90
                  ....*....|....*....
gi 2324333523  81 SGIAVGMATNIPPHNLTEV 99
Cdd:TIGR01063 165 SGIAVGMATNIPPHNLGEI 183
TOP4c cd00187
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), ...
 1-99 4.02e-67

DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes in DNA topology by catalysing the concerted breakage and rejoining of DNA strands during normal cellular growth.


Pssm-ID: 238111 [Multi-domain]  Cd Length: 445  Bit Score: 207.42  E-value: 4.02e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2324333523   1 MAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTERIPDVMPTKIPNLLVNGA 80
Cdd:cd00187    63 MAQDFSNNIPLLDPQGNFGSRDGDDAAAMRYTETRLSPIARLLLPDIDDPTVDFVPNYDGQEVEPEVLPPIFPNLLVNGS 142

                          90
                  ....*....|....*....
gi 2324333523  81 SGIAVGMATNIPPHNLTEV 99
Cdd:cd00187   143 SGIAVGMATNIPPHNLREV 161
TOP4c smart00434
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC
 1-99 1.14e-63

DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC


Pssm-ID: 214660 [Multi-domain]  Cd Length: 444  Bit Score: 198.56  E-value: 1.14e-63
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2324333523    1 MAQPFSLRYMLVDGQGNFGSI-DGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTERIPDVMPTKIPNLLVNG 79
Cdd:smart00434  82 MAQDFSNNYPLLDGQGNFGSRlDGDDAAAMRYTETRLSPLARLLLPDIDKDTVDFVPNYDGQEIEPTVLPPIIPNLLVNG 161

                           90       100
                   ....*....|....*....|
gi 2324333523   80 ASGIAVGMATNIPPHNLTEV 99
Cdd:smart00434 162 SSGIAVGMATNIPPHNLREV 181
DNA_topoisoIV pfam00521
DNA gyrase/topoisomerase IV, subunit A;
1-99 6.03e-61

DNA gyrase/topoisomerase IV, subunit A;


Pssm-ID: 459843 [Multi-domain]  Cd Length: 432  Bit Score: 191.23  E-value: 6.03e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2324333523   1 MAQPFSLRYMLVDGQGNFGS-IDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTERIPDVMPTKIPNLLVNG 79
Cdd:pfam00521  60 MAQDFVGNIPLLDGQGNFGSrIDGDKDAAMRYTETRLSKIARELFPDIDDDTVDYVPNYDGTEVEPTVLPPIIPNLLVNG 139

                          90       100
                  ....*....|....*....|
gi 2324333523  80 ASGIAVGMATNIPPHNLTEV 99
Cdd:pfam00521 140 AEGIAVGMATNIPPHNLREI 159
 
Name Accession Description Interval E-value
PRK05560 PRK05560
DNA gyrase subunit A; Validated
 1-99 5.33e-83

DNA gyrase subunit A; Validated


Pssm-ID: 235502 [Multi-domain]  Cd Length: 805  Bit Score: 256.88  E-value: 5.33e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2324333523   1 MAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTERIPDVMPTKIPNLLVNGA 80
Cdd:PRK05560   89 MAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARMSKIAHELLADIDKETVDFVPNYDGSEQEPTVLPARFPNLLVNGS 168

                          90
                  ....*....|....*....
gi 2324333523  81 SGIAVGMATNIPPHNLTEV 99
Cdd:PRK05560  169 SGIAVGMATNIPPHNLGEV 187
GyrA COG0188
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair];
1-99 1.02e-80

DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair];


Pssm-ID: 439958 [Multi-domain]  Cd Length: 804  Bit Score: 250.73  E-value: 1.02e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2324333523   1 MAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTERIPDVMPTKIPNLLVNGA 80
Cdd:COG0188    94 MAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARLAKIAEELLADIDKDTVDFVPNYDGSEQEPTVLPARFPNLLVNGS 173

                          90
                  ....*....|....*....
gi 2324333523  81 SGIAVGMATNIPPHNLTEV 99
Cdd:COG0188   174 SGIAVGMATNIPPHNLGEV 192
gyrA TIGR01063
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). ...
 1-99 4.69e-70

DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). Two apparently independently arising families, one in the Proteobacteria and one in Gram-positive lineages, are both designated toposisomerase IV. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273423 [Multi-domain]  Cd Length: 800  Bit Score: 222.57  E-value: 4.69e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2324333523   1 MAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTERIPDVMPTKIPNLLVNGA 80
Cdd:TIGR01063  85 MAQDFSLRYPLVDGQGNFGSIDGDPPAAMRYTEARLTKIAEELLRDIDKETVDFVPNYDGSEQEPTVLPSRFPNLLVNGS 164

                          90
                  ....*....|....*....
gi 2324333523  81 SGIAVGMATNIPPHNLTEV 99
Cdd:TIGR01063 165 SGIAVGMATNIPPHNLGEI 183
PRK05561 PRK05561
DNA topoisomerase 4 subunit A;
1-99 7.32e-68

DNA topoisomerase 4 subunit A;


Pssm-ID: 235503 [Multi-domain]  Cd Length: 742  Bit Score: 215.74  E-value: 7.32e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2324333523   1 MAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTERIPDVMPTKIPNLLVNGA 80
Cdd:PRK05561   94 MAQDFSYRYPLVDGQGNFGSIDGDPAAAMRYTEARLSPIAELLLEEIDEGTVDFVPNFDGTLKEPTVLPARFPNLLLNGA 173

                          90
                  ....*....|....*....
gi 2324333523  81 SGIAVGMATNIPPHNLTEV 99
Cdd:PRK05561  174 TGIAVGMATDIPPHNLREV 192
TOP4c cd00187
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), ...
 1-99 4.02e-67

DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes in DNA topology by catalysing the concerted breakage and rejoining of DNA strands during normal cellular growth.


Pssm-ID: 238111 [Multi-domain]  Cd Length: 445  Bit Score: 207.42  E-value: 4.02e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2324333523   1 MAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTERIPDVMPTKIPNLLVNGA 80
Cdd:cd00187    63 MAQDFSNNIPLLDPQGNFGSRDGDDAAAMRYTETRLSPIARLLLPDIDDPTVDFVPNYDGQEVEPEVLPPIFPNLLVNGS 142

                          90
                  ....*....|....*....
gi 2324333523  81 SGIAVGMATNIPPHNLTEV 99
Cdd:cd00187   143 SGIAVGMATNIPPHNLREV 161
TOP4c smart00434
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC
 1-99 1.14e-63

DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC


Pssm-ID: 214660 [Multi-domain]  Cd Length: 444  Bit Score: 198.56  E-value: 1.14e-63
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2324333523    1 MAQPFSLRYMLVDGQGNFGSI-DGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTERIPDVMPTKIPNLLVNG 79
Cdd:smart00434  82 MAQDFSNNYPLLDGQGNFGSRlDGDDAAAMRYTETRLSPLARLLLPDIDKDTVDFVPNYDGQEIEPTVLPPIIPNLLVNG 161

                           90       100
                   ....*....|....*....|
gi 2324333523   80 ASGIAVGMATNIPPHNLTEV 99
Cdd:smart00434 162 SSGIAVGMATNIPPHNLREV 181
DNA_topoisoIV pfam00521
DNA gyrase/topoisomerase IV, subunit A;
1-99 6.03e-61

DNA gyrase/topoisomerase IV, subunit A;


Pssm-ID: 459843 [Multi-domain]  Cd Length: 432  Bit Score: 191.23  E-value: 6.03e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2324333523   1 MAQPFSLRYMLVDGQGNFGS-IDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTERIPDVMPTKIPNLLVNG 79
Cdd:pfam00521  60 MAQDFVGNIPLLDGQGNFGSrIDGDKDAAMRYTETRLSKIARELFPDIDDDTVDYVPNYDGTEVEPTVLPPIIPNLLVNG 139

                          90       100
                  ....*....|....*....|
gi 2324333523  80 ASGIAVGMATNIPPHNLTEV 99
Cdd:pfam00521 140 AEGIAVGMATNIPPHNLREI 159
PRK13979 PRK13979
DNA topoisomerase IV subunit A; Provisional
 1-99 6.14e-51

DNA topoisomerase IV subunit A; Provisional


Pssm-ID: 237576 [Multi-domain]  Cd Length: 957  Bit Score: 171.06  E-value: 6.14e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2324333523   1 MAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTERIPDVMPTKIPNLLVNGA 80
Cdd:PRK13979   97 LAQDFTTRMPLIDGHGNWGSIDGDSAAAMRYTEARLTPIAMEMLRDIDKDVVNMVDNYSDSEKEPEVLPARYPNLLVNGA 176

                          90
                  ....*....|....*....
gi 2324333523  81 SGIAVGMATNIPPHNLTEV 99
Cdd:PRK13979  177 FGIAVGLATNIPPHNLKEV 195
parC_Gneg TIGR01062
DNA topoisomerase IV, A subunit, proteobacterial; Operationally, topoisomerase IV is a type II ...
 1-99 1.76e-46

DNA topoisomerase IV, A subunit, proteobacterial; Operationally, topoisomerase IV is a type II topoisomerase required for the decatenation of chromosome segregation. Not every bacterium has both a topo II and a topo IV. The topo IV families of the Gram-positive bacteria and the Gram-negative bacteria appear not to represent a single clade among the type II topoisomerases, and are represented by separate models for this reason. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 130134 [Multi-domain]  Cd Length: 735  Bit Score: 157.76  E-value: 1.76e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2324333523   1 MAQPFSLRYMLVDGQGNFGSIDG-DSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTERIPDVMPTKIPNLLVNG 79
Cdd:TIGR01062  85 MAQPFSYRYPLVDGQGNWGAPDDpKSFAAMRYTESRLSKISELLLEELGQGTVDFRPNFDGTLLEPVILPARLPNILLNG 164

                          90       100
                  ....*....|....*....|
gi 2324333523  80 ASGIAVGMATNIPPHNLTEV 99
Cdd:TIGR01062 165 TTGIAVGMATDIPPHNLHEL 184
PRK09631 PRK09631
DNA topoisomerase IV subunit A; Provisional
 10-99 1.75e-28

DNA topoisomerase IV subunit A; Provisional


Pssm-ID: 236598 [Multi-domain]  Cd Length: 635  Bit Score: 107.10  E-value: 1.75e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2324333523  10 MLVDGQGNFGSI-DGDSAAAMRYTEIRLAKIAHELMadLEKETVDFVDNYDGTERIPDVMPTKIPNLLVNGASGIAVGMA 88
Cdd:PRK09631   84 LFIDKQGNFGNLfTGDPASAARYIECRLTPLAKEVL--YNKEITEYEPSYDGRNNEPLCLPAKIPVILIQGAEGIAVGMA 161

                          90
                  ....*....|.
gi 2324333523  89 TNIPPHNLTEV 99
Cdd:PRK09631  162 TKILPHNFNEI 172
PRK09630 PRK09630
DNA topoisomerase IV subunit A; Provisional
 11-99 8.62e-25

DNA topoisomerase IV subunit A; Provisional


Pssm-ID: 170022  Cd Length: 479  Bit Score: 96.12  E-value: 8.62e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2324333523  11 LVDGQGNFGS-IDGDSAAAMRYTEIRLAKIAHELMadLEKETVDFVDNYDGTERIPDVMPTKIPNLLVNGASGIAVGMAT 89
Cdd:PRK09630   85 LIDTQGNFGNpLTGDPHAAARYIEARLSPLAKEVL--FNTDLMTFHDSYDGREKEPDILPAKLPLLLLHGVDGIAVGMTT 162

                          90
                  ....*....|
gi 2324333523  90 NIPPHNLTEV 99
Cdd:PRK09630  163 KIFPHNFCEL 172
PRK12758 PRK12758
DNA gyrase/topoisomerase IV subunit A;
10-98 8.47e-23

DNA gyrase/topoisomerase IV subunit A;


Pssm-ID: 237192 [Multi-domain]  Cd Length: 869  Bit Score: 90.83  E-value: 8.47e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2324333523  10 MLVDGQGNFGSI-DGDSAAAMRYTEIRLAKIAHELMadLEKETVDFVDNYDGTERIPDVMPTKIPNLLVNGASGIAVGMA 88
Cdd:PRK12758  103 LLIDTQGNWGNIlTGDGAAAPRYIEARLSKFALEVV--FNPKTTEWQLSYDGRKKEPVTLPVKFPLLLAQGAEGIAVGLS 180

                          90
                  ....*....|
gi 2324333523  89 TNIPPHNLTE 98
Cdd:PRK12758  181 TKILPHNFNE 190
52 PHA02592
DNA topisomerase II medium subunit; Provisional
 1-99 2.36e-18

DNA topisomerase II medium subunit; Provisional


Pssm-ID: 222896 [Multi-domain]  Cd Length: 439  Bit Score: 78.17  E-value: 2.36e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2324333523   1 MAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLakiaHELMADLEKETvDFVDNYDGTERIPDV--MPTkIPNLLVN 78
Cdd:PHA02592   87 MANTWNNNIPLLDGQGNFGSRLVQKAAAARYIFARV----HDNFRKIYKDE-DLAPVHEDPEHIPPAfyLPI-IPMVLLN 160

                          90       100
                  ....*....|....*....|.
gi 2324333523  79 GASGIAVGMATNIPPHNLTEV 99
Cdd:PHA02592  161 GVSGIATGYATNILPHSPKSV 181
PTZ00108 PTZ00108
DNA topoisomerase 2-like protein; Provisional
 1-95 4.16e-12

DNA topoisomerase 2-like protein; Provisional


Pssm-ID: 240271 [Multi-domain]  Cd Length: 1388  Bit Score: 60.45  E-value: 4.16e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2324333523    1 MAQPF----SLRYMLVDGQgnFGS--IDGDSAAAMRYTEIRLAKIA----HElmADleketvDFVDNY---DGTERIPD- 66
Cdd:PTZ00108   738 MAQNFvgsnNINLLYPCGQ--FGSrlQGGKDHAAARYIFTKLSKITryifPE--ED------DPILDYledDGQSVEPFy 807

                           90       100
                   ....*....|....*....|....*....
gi 2324333523   67 VMPTkIPNLLVNGASGIAVGMATNIPPHN 95
Cdd:PTZ00108   808 YVPI-IPMVLVNGAEGIGTGFSTSIPNYN 835
PLN03128 PLN03128
DNA topoisomerase 2; Provisional
 1-99 1.30e-09

DNA topoisomerase 2; Provisional


Pssm-ID: 215593 [Multi-domain]  Cd Length: 1135  Bit Score: 53.17  E-value: 1.30e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2324333523    1 MAQPF--SLRYMLVDGQGNFGS--IDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNyDGTERIPD-VMPTkIPNL 75
Cdd:PLN03128   731 MAQDFvgSNNINLLTPSGQFGTrlQGGKDAASARYIFTRLSPITRALFPKDDDVLLNYLNE-DGQSIEPEwYCPI-IPMV 808

                           90       100
                   ....*....|....*....|....
gi 2324333523   76 LVNGASGIAVGMATNIPPHNLTEV 99
Cdd:PLN03128   809 LVNGSEGIGTGWSTFIPNYNPRDI 832
PLN03237 PLN03237
DNA topoisomerase 2; Provisional
 1-95 4.83e-08

DNA topoisomerase 2; Provisional


Pssm-ID: 215641 [Multi-domain]  Cd Length: 1465  Bit Score: 49.09  E-value: 4.83e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2324333523    1 MAQPF----SLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNyDGTERIPD-VMPTkIPNL 75
Cdd:PLN03237   756 MAQDFvgsnNINLLLPNGQFGTRLQGGKDHASARYIFTRLSPITRFLFPKDDDILLDYLNE-DGQSIEPTwYMPI-IPTV 833

                           90       100
                   ....*....|....*....|
gi 2324333523   76 LVNGASGIAVGMATNIPPHN 95
Cdd:PLN03237   834 LVNGAEGIGTGWSTFIPNYN 853
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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