NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2271350946|gb|UTM45830|]
View 

class II aldolase/adducin family protein [Glutamicibacter mysorens]

Protein Classification

class II aldolase/adducin family protein( domain architecture ID 10000749)

class II aldolase/adducin family protein similar to L-fuculose phosphate aldolase, which catalyzes the reversible aldol cleavage of L-fuculose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
AraD COG0235
5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar ...
 6-219 1.70e-44

5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation) [Amino acid transport and metabolism, Carbohydrate transport and metabolism]; 5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation) is part of the Pathway/BioSystem: Urea cycle


:

Pssm-ID: 440005 [Multi-domain]  Cd Length: 208  Bit Score: 148.44  E-value: 1.70e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271350946   6 YQKERHQIALACRVLAARGLADGILGHISYRVKDDLILVRCRGVnerGLGYTEAQDIRLVDLDGNPasaqeLDGWKVPN- 84
Cdd:COG0235     3 EEELREELAAAGRRLARRGLVDGTAGNISVRLDDDRFLITPSGV---DFGELTPEDLVVVDLDGNV-----VEGDLKPSs 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271350946  85 ELPLHAAVLRKHLEVQSVVHAHPPTVVACDLAGIEIRPIigayDMPGAKLAAAGVPVHPrSVLIRNQRLAEEMVESMHDK 164
Cdd:COG0235    75 ETPLHLAIYRARPDVGAVVHTHSPYATALSALGEPLPPL----EQTEAAAFLGDVPVVP-YAGPGTEELAEAIAEALGDR 149

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2271350946 165 PVVLLRGHGMTSAAASVEQAVLQAISVNVIATLSLeIVSAGGQLQDISQEDMAEL 219
Cdd:COG0235   150 PAVLLRNHGVVVWGKDLAEAFDRAEVLEEAARIQL-LALALGGPLVLSDEEIDKL 203
 
Name Accession Description Interval E-value
AraD COG0235
5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar ...
 6-219 1.70e-44

5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation) [Amino acid transport and metabolism, Carbohydrate transport and metabolism]; 5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation) is part of the Pathway/BioSystem: Urea cycle


Pssm-ID: 440005 [Multi-domain]  Cd Length: 208  Bit Score: 148.44  E-value: 1.70e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271350946   6 YQKERHQIALACRVLAARGLADGILGHISYRVKDDLILVRCRGVnerGLGYTEAQDIRLVDLDGNPasaqeLDGWKVPN- 84
Cdd:COG0235     3 EEELREELAAAGRRLARRGLVDGTAGNISVRLDDDRFLITPSGV---DFGELTPEDLVVVDLDGNV-----VEGDLKPSs 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271350946  85 ELPLHAAVLRKHLEVQSVVHAHPPTVVACDLAGIEIRPIigayDMPGAKLAAAGVPVHPrSVLIRNQRLAEEMVESMHDK 164
Cdd:COG0235    75 ETPLHLAIYRARPDVGAVVHTHSPYATALSALGEPLPPL----EQTEAAAFLGDVPVVP-YAGPGTEELAEAIAEALGDR 149

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2271350946 165 PVVLLRGHGMTSAAASVEQAVLQAISVNVIATLSLeIVSAGGQLQDISQEDMAEL 219
Cdd:COG0235   150 PAVLLRNHGVVVWGKDLAEAFDRAEVLEEAARIQL-LALALGGPLVLSDEEIDKL 203
Aldolase_II pfam00596
Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and ...
 12-191 7.56e-38

Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and adducins which have not been ascribed any enzymatic function.


Pssm-ID: 459862 [Multi-domain]  Cd Length: 178  Bit Score: 130.36  E-value: 7.56e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271350946  12 QIALACRVLAARGLADGILGHISYRVKDDLILVRCRGVNERGLgytEAQDIRLVDLDGNPASaqelDGWKVPNELPLHAA 91
Cdd:pfam00596   2 ELAAAGRLLARRGLVEGTGGNISVRLPGDGFLITPSGVDFGEL---TPEDLVVVDLDGNVVE----GGLKPSSETPLHLA 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271350946  92 VLRKHLEVQSVVHAHPPTVVACDLAGIEIRPIigayDMPGAKLAAAGVPVHPRSVLiRNQRLAEEMVESM-HDKPVVLLR 170
Cdd:pfam00596  75 IYRARPDAGAVVHTHSPYATALSLAKEGLPPI----TQEAADFLGGDIPIIPYYTP-GTEELGERIAEALgGDRKAVLLR 149

                         170       180
                  ....*....|....*....|.
gi 2271350946 171 GHGMTSAAASVEQAVLQAISV 191
Cdd:pfam00596 150 NHGLLVWGKTLEEAFYLAEEL 170
Aldolase_II smart01007
Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and ...
 13-195 6.34e-32

Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and adducins which have not been ascribed any enzymatic function.


Pssm-ID: 214970 [Multi-domain]  Cd Length: 185  Bit Score: 115.43  E-value: 6.34e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271350946   13 IALACRVLAARGLADGILGHISYRVKD-DLILVRCRGVNergLGYTEAQDIRLVDLDGNPASAQelDGWKVPNELPLHAA 91
Cdd:smart01007   1 LAAACRLLARRGLVEGTGGNISARVGEeDLFLITPSGVD---FGELTASDLVVVDLDGNVVEGG--GGPKPSSETPLHLA 75

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271350946   92 VLRKHLEVQSVVHAHPPTVVACDLAGIEIRPIIgaYDMPGAKLaAAGVPVHP--RSVLIRNQ---RLAEEMVESMHDKPV 166
Cdd:smart01007  76 IYRARPDVGAVVHTHSPYATALAALGKPLPLLP--TEQAAAFL-GGEIPYAPyaGPGTELAEegaELAEALAEALPDRPA 152

                          170       180
                   ....*....|....*....|....*....
gi 2271350946  167 VLLRGHGMTSAAASVEQAVLQAISVNVIA 195
Cdd:smart01007 153 VLLRNHGLLVWGKTLEEAFDLAEELEEAA 181
Aldolase_II cd00398
Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes ...
 12-219 3.96e-17

Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). Class II enzymes are further divided into two sub-classes A and B. This family includes class II A aldolases and adducins which has not been ascribed any enzymatic function. Members of this class are primarily bacterial and eukaryotic in origin and include L-fuculose-1-phosphate, L-rhamnulose-1-phosphate aldolases and L-ribulose-5-phosphate 4-epimerases. They all share the ability to promote carbon-carbon bond cleavage and stabilize enolate intermediates using divalent cations.


Pssm-ID: 238232 [Multi-domain]  Cd Length: 209  Bit Score: 77.02  E-value: 3.96e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271350946  12 QIALACRVLAARGLADGILGHISYRVKDDLILVrcrgVNERGLGYTE--AQDIRLVDLDGnpasaQELDGWKVPNELPLH 89
Cdd:cd00398     6 KIIAACLLLDLYGWVTGTGGNVSARDRDRGYFL----ITPSGVDYEEmtASDLVVVDAQG-----KVVEGKKPSSETPLH 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271350946  90 AAVLRKHLEVQSVVHAHPPTVVACDLAGIEIRPIIGayDMPGAKLaAAGVPVHPRSVL-----IRNQRLAEEMVESmhdk 164
Cdd:cd00398    77 LALYRARPDIGCIVHTHSTHATAVSQLKEGLIPAGH--TACAVYF-TGDIPCTPYMTPetgedEIGTQRALGFPNS---- 149

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2271350946 165 PVVLLRGHGMTSAAASVEQAVLQAISVNVIATLSLEIVSAGGQLQDISQEDMAEL 219
Cdd:cd00398   150 KAVLLRNHGLFAWGPTLDEAFHLAVVLEVAAEIQLKALSMGGQLPPISLELLNKE 204
PRK07090 PRK07090
class II aldolase/adducin domain protein; Provisional
 10-237 2.36e-14

class II aldolase/adducin domain protein; Provisional


Pssm-ID: 180832  Cd Length: 260  Bit Score: 70.44  E-value: 2.36e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271350946  10 RHQIALACRVLAARGLADGILGHISYRVKDDLILVRCRgvneRGLGYTE--AQDIRLVDLDGNPasaqeLDGWKVPNelP 87
Cdd:PRK07090   32 RQKLALTCRILFDAGHDSGLAGQITARAEAPGTYYTQR----LGLGFDEitASNLLLVDEDLNV-----LDGEGMPN--P 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271350946  88 ---LHAAVLRKHLEVQSVVHAHPPTVVAcdLAGIEIRPIIGAYDMPG-----AKLAA-AGVPVHprsvlirNQRlAEEMV 158
Cdd:PRK07090  101 anrFHSWIYRARPDVNCIIHTHPPHVAA--LSMLEVPLVVSHMDTCPlyddcAFLKDwPGVPVG-------NEE-GEIIS 170

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2271350946 159 ESMHDKPVVLLRGHGMTSAAASVEQAVLQAISVNVIATLSLeIVSAGGQLQDISQEDMAELPDLgsgfnTSTAWRHELA 237
Cdd:PRK07090  171 AALGDKRAILLSHHGQLVAGKSIEEACVLALLIERAARLQL-LAMAAGPIKPIPPELAREAHDW-----ISTPKRSAAT 243
 
Name Accession Description Interval E-value
AraD COG0235
5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar ...
 6-219 1.70e-44

5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation) [Amino acid transport and metabolism, Carbohydrate transport and metabolism]; 5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation) is part of the Pathway/BioSystem: Urea cycle


Pssm-ID: 440005 [Multi-domain]  Cd Length: 208  Bit Score: 148.44  E-value: 1.70e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271350946   6 YQKERHQIALACRVLAARGLADGILGHISYRVKDDLILVRCRGVnerGLGYTEAQDIRLVDLDGNPasaqeLDGWKVPN- 84
Cdd:COG0235     3 EEELREELAAAGRRLARRGLVDGTAGNISVRLDDDRFLITPSGV---DFGELTPEDLVVVDLDGNV-----VEGDLKPSs 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271350946  85 ELPLHAAVLRKHLEVQSVVHAHPPTVVACDLAGIEIRPIigayDMPGAKLAAAGVPVHPrSVLIRNQRLAEEMVESMHDK 164
Cdd:COG0235    75 ETPLHLAIYRARPDVGAVVHTHSPYATALSALGEPLPPL----EQTEAAAFLGDVPVVP-YAGPGTEELAEAIAEALGDR 149

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2271350946 165 PVVLLRGHGMTSAAASVEQAVLQAISVNVIATLSLeIVSAGGQLQDISQEDMAEL 219
Cdd:COG0235   150 PAVLLRNHGVVVWGKDLAEAFDRAEVLEEAARIQL-LALALGGPLVLSDEEIDKL 203
Aldolase_II pfam00596
Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and ...
 12-191 7.56e-38

Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and adducins which have not been ascribed any enzymatic function.


Pssm-ID: 459862 [Multi-domain]  Cd Length: 178  Bit Score: 130.36  E-value: 7.56e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271350946  12 QIALACRVLAARGLADGILGHISYRVKDDLILVRCRGVNERGLgytEAQDIRLVDLDGNPASaqelDGWKVPNELPLHAA 91
Cdd:pfam00596   2 ELAAAGRLLARRGLVEGTGGNISVRLPGDGFLITPSGVDFGEL---TPEDLVVVDLDGNVVE----GGLKPSSETPLHLA 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271350946  92 VLRKHLEVQSVVHAHPPTVVACDLAGIEIRPIigayDMPGAKLAAAGVPVHPRSVLiRNQRLAEEMVESM-HDKPVVLLR 170
Cdd:pfam00596  75 IYRARPDAGAVVHTHSPYATALSLAKEGLPPI----TQEAADFLGGDIPIIPYYTP-GTEELGERIAEALgGDRKAVLLR 149

                         170       180
                  ....*....|....*....|.
gi 2271350946 171 GHGMTSAAASVEQAVLQAISV 191
Cdd:pfam00596 150 NHGLLVWGKTLEEAFYLAEEL 170
Aldolase_II smart01007
Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and ...
 13-195 6.34e-32

Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and adducins which have not been ascribed any enzymatic function.


Pssm-ID: 214970 [Multi-domain]  Cd Length: 185  Bit Score: 115.43  E-value: 6.34e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271350946   13 IALACRVLAARGLADGILGHISYRVKD-DLILVRCRGVNergLGYTEAQDIRLVDLDGNPASAQelDGWKVPNELPLHAA 91
Cdd:smart01007   1 LAAACRLLARRGLVEGTGGNISARVGEeDLFLITPSGVD---FGELTASDLVVVDLDGNVVEGG--GGPKPSSETPLHLA 75

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271350946   92 VLRKHLEVQSVVHAHPPTVVACDLAGIEIRPIIgaYDMPGAKLaAAGVPVHP--RSVLIRNQ---RLAEEMVESMHDKPV 166
Cdd:smart01007  76 IYRARPDVGAVVHTHSPYATALAALGKPLPLLP--TEQAAAFL-GGEIPYAPyaGPGTELAEegaELAEALAEALPDRPA 152

                          170       180
                   ....*....|....*....|....*....
gi 2271350946  167 VLLRGHGMTSAAASVEQAVLQAISVNVIA 195
Cdd:smart01007 153 VLLRNHGLLVWGKTLEEAFDLAEELEEAA 181
Aldolase_II cd00398
Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes ...
 12-219 3.96e-17

Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). Class II enzymes are further divided into two sub-classes A and B. This family includes class II A aldolases and adducins which has not been ascribed any enzymatic function. Members of this class are primarily bacterial and eukaryotic in origin and include L-fuculose-1-phosphate, L-rhamnulose-1-phosphate aldolases and L-ribulose-5-phosphate 4-epimerases. They all share the ability to promote carbon-carbon bond cleavage and stabilize enolate intermediates using divalent cations.


Pssm-ID: 238232 [Multi-domain]  Cd Length: 209  Bit Score: 77.02  E-value: 3.96e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271350946  12 QIALACRVLAARGLADGILGHISYRVKDDLILVrcrgVNERGLGYTE--AQDIRLVDLDGnpasaQELDGWKVPNELPLH 89
Cdd:cd00398     6 KIIAACLLLDLYGWVTGTGGNVSARDRDRGYFL----ITPSGVDYEEmtASDLVVVDAQG-----KVVEGKKPSSETPLH 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271350946  90 AAVLRKHLEVQSVVHAHPPTVVACDLAGIEIRPIIGayDMPGAKLaAAGVPVHPRSVL-----IRNQRLAEEMVESmhdk 164
Cdd:cd00398    77 LALYRARPDIGCIVHTHSTHATAVSQLKEGLIPAGH--TACAVYF-TGDIPCTPYMTPetgedEIGTQRALGFPNS---- 149

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2271350946 165 PVVLLRGHGMTSAAASVEQAVLQAISVNVIATLSLEIVSAGGQLQDISQEDMAEL 219
Cdd:cd00398   150 KAVLLRNHGLFAWGPTLDEAFHLAVVLEVAAEIQLKALSMGGQLPPISLELLNKE 204
PRK07090 PRK07090
class II aldolase/adducin domain protein; Provisional
 10-237 2.36e-14

class II aldolase/adducin domain protein; Provisional


Pssm-ID: 180832  Cd Length: 260  Bit Score: 70.44  E-value: 2.36e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271350946  10 RHQIALACRVLAARGLADGILGHISYRVKDDLILVRCRgvneRGLGYTE--AQDIRLVDLDGNPasaqeLDGWKVPNelP 87
Cdd:PRK07090   32 RQKLALTCRILFDAGHDSGLAGQITARAEAPGTYYTQR----LGLGFDEitASNLLLVDEDLNV-----LDGEGMPN--P 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271350946  88 ---LHAAVLRKHLEVQSVVHAHPPTVVAcdLAGIEIRPIIGAYDMPG-----AKLAA-AGVPVHprsvlirNQRlAEEMV 158
Cdd:PRK07090  101 anrFHSWIYRARPDVNCIIHTHPPHVAA--LSMLEVPLVVSHMDTCPlyddcAFLKDwPGVPVG-------NEE-GEIIS 170

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2271350946 159 ESMHDKPVVLLRGHGMTSAAASVEQAVLQAISVNVIATLSLeIVSAGGQLQDISQEDMAELPDLgsgfnTSTAWRHELA 237
Cdd:PRK07090  171 AALGDKRAILLSHHGQLVAGKSIEEACVLALLIERAARLQL-LAMAAGPIKPIPPELAREAHDW-----ISTPKRSAAT 243
PRK06833 PRK06833
L-fuculose-phosphate aldolase;
5-219 5.24e-13

L-fuculose-phosphate aldolase;


Pssm-ID: 180717 [Multi-domain]  Cd Length: 214  Bit Score: 65.93  E-value: 5.24e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271350946   5 LYQKERHQIALACRVLAARGLADGILGHIS-YRVKDDLIlvrcrGVNERGLGYTE--AQDIRLVDLDGNpasaqELDGWK 81
Cdd:PRK06833    2 LLQKEREEIVAYGKKLISSGLTKGTGGNISiFNREQGLM-----AITPSGIDYFEikPEDIVIMDLDGK-----VVEGER 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271350946  82 VPN-ELPLHAAVLRKHLEVQSVVHAHPP--TVVAC---DLAGIEIRPIIGAYDMPGAKLAAAGVpvhprsvlirnQRLAE 155
Cdd:PRK06833   72 KPSsELDMHLIFYRNREDINAIVHTHSPyaTTLAClgwELPAVHYLIAVAGPNVRCAEYATFGT-----------KELAE 140

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2271350946 156 EMVESMHDKPVVLLRGHGMTSAAASVEQAVLQAISVNVIATLSLEIVSAGGQ--LQDISQEDMAEL 219
Cdd:PRK06833  141 NAFEAMEDRRAVLLANHGLLAGANNLKNAFNIAEEIEFCAEIYYQTKSIGEPklLPEDEMENMAEK 206
PRK08660 PRK08660
aldolase;
11-184 4.62e-11

aldolase;


Pssm-ID: 181527 [Multi-domain]  Cd Length: 181  Bit Score: 59.97  E-value: 4.62e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271350946  11 HQIALACRVLAARGLADGILGHISYRVKDDLILVRcRGVNergLGYTEAQDIRLVDLDGNpasaQELDGwKVPNELPLHA 90
Cdd:PRK08660    3 QEFARIGKKLFAHGLVSSHFGNISVRTGDGLLITR-TGSM---LDEITEGDVIEVGIDDD----GSVDP-LASSETPVHR 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271350946  91 AVLRkHLEVQSVVHAHPPTVVACDLAGIEIRPII--GAYDMPgaKLAAAGVPVHPRSvlirnqrLAEEMVESMHDKPVVL 168
Cdd:PRK08660   74 AIYR-RTSAKAIVHAHPPYAVALSLLEDEIVPLDseGLYFLG--TIPVVGGDIGSGE-------LAENVARALSEHKGVV 143

                         170
                  ....*....|....*.
gi 2271350946 169 LRGHGMTSAAASVEQA 184
Cdd:PRK08660  144 VRGHGTFAIGKTLEEA 159
PRK08333 PRK08333
aldolase;
23-197 1.45e-10

aldolase;


Pssm-ID: 181393 [Multi-domain]  Cd Length: 184  Bit Score: 58.68  E-value: 1.45e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271350946  23 RGLADGILGHISYRVkDDLILVRCRG--VNErglgYTEAQdIRLVDLDGNpasaqELDGWKVPNELPLHAAVLRKHLEVQ 100
Cdd:PRK08333   18 RGLTAAFGGNLSIRV-GNLVFIKATGsvMDE----LTREQ-VAVIDLNGN-----QLSSVRPSSEYRLHLAVYRNRPDVR 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271350946 101 SVVHAHPP-TVVACDLAGIEIrPIIgaydMPGAKLAAAGVPVHPrsvlIR---NQRLAEEMVESMHDKPVVLLRGHGMTS 176
Cdd:PRK08333   87 AIAHLHPPySIVASTLLEEEL-PII----TPEAELYLKKIPILP----FRpagSVELAEQVAEAMKEYDAVIMERHGIVT 157

                         170       180
                  ....*....|....*....|.
gi 2271350946 177 AAASVEQAVLQAISVNVIATL 197
Cdd:PRK08333  158 VGRSLREAFYKAELVEESAKL 178
PRK08130 PRK08130
putative aldolase; Validated
 7-185 6.63e-10

putative aldolase; Validated


Pssm-ID: 181241 [Multi-domain]  Cd Length: 213  Bit Score: 57.19  E-value: 6.63e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271350946   7 QKERHQIALACRVLAARGLADGILGHISYRVKDDLILVRCRGVNergLGYTEAQDIRLVDLDGNPASaqeldGWKVPNEL 86
Cdd:PRK08130    4 QALREEIVRLGRSLFQRGYTVGSAGNISARLDDGGWLVTPTGSC---LGRLDPARLSKVDADGNWLS-----GDKPSKEV 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271350946  87 PLHAAVLRKHLEVQSVVHAHPPTVVA--CdLAGIE----IRPIIGAYDMPGAKLAaagvpvhprsvLIRNQR-----LAE 155
Cdd:PRK08130   76 PLHRAIYRNNPECGAVVHLHSTHLTAlsC-LGGLDptnvLPPFTPYYVMRVGHVP-----------LIPYYRpgdpaIAE 143

                         170       180       190
                  ....*....|....*....|....*....|
gi 2271350946 156 EMVESMHDKPVVLLRGHGMTSAAASVEQAV 185
Cdd:PRK08130  144 ALAGLAARYRAVLLANHGPVVWGSSLEAAV 173
PRK06557 PRK06557
L-ribulose-5-phosphate 4-epimerase; Validated
 2-221 1.79e-09

L-ribulose-5-phosphate 4-epimerase; Validated


Pssm-ID: 235829 [Multi-domain]  Cd Length: 221  Bit Score: 56.17  E-value: 1.79e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271350946   2 TLDLYQKERHQIALACRVLAARGLADGILGHISYRVKD-DLILVRCRGVNerglgYTE--AQDIRLVDLDGNPasaqeLD 78
Cdd:PRK06557    4 VRAMVEKLREEVCKLHLELPKYGLVVWTSGNVSARDPGtDLVVIKPSGVS-----YDDltPEDMVVVDLDGNV-----VE 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271350946  79 GWKVPN-ELPLHAAVLRKHLEVQSVVHAHPPTVVACDLAGIEIRPIIGAYdmpgAKLAAAGVPVHPRSvLIRNQRLAEEM 157
Cdd:PRK06557   74 GDLKPSsDTASHLYVYRHMPDVGGVVHTHSTYATAWAARGEPIPCVLTAM----ADEFGGPIPVGPFA-LIGDEAIGKGI 148

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2271350946 158 VESM--HDKPVVLLRGHGMTSAAASVEQAVLQAISVNVIATlSLEIVSAGGQLQDISQEDMAELPD 221
Cdd:PRK06557  149 VETLkgGRSPAVLMQNHGVFTIGKDAEDAVKAAVMVEEVAR-TVHIARQLGEPIPIPQEEIDRLYD 213
PRK06486 PRK06486
aldolase;
10-184 6.15e-09

aldolase;


Pssm-ID: 235814  Cd Length: 262  Bit Score: 55.10  E-value: 6.15e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271350946  10 RHQIALACRVLAARGLADGILGHISYRV--KDDLILvrcrgVNERGLGYTE--AQDIRLVDLDGNPASAqelDGWKVPNE 85
Cdd:PRK06486   28 RVDLAACFRAAARHGLEEGICNHFSAVLpgHDDLFL-----VNPYGYAFSEitASDLLICDFDGNVLAG---RGEPEATA 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271350946  86 LPLHAAVLRKHLEVQSVVHAHPPTVVAcdLAGIEIRPIIgaydmpgaKLAAAGVPVHPRSVLIRN-------QRLAEEMV 158
Cdd:PRK06486  100 FFIHARIHRAIPRAKAAFHTHMPYATA--LSLTEGRPLT--------TLGQTALKFYGRTAVDEDynglaldAAEGDRIA 169

                         170       180
                  ....*....|....*....|....*.
gi 2271350946 159 ESMHDKPVVLLRGHGMTSAAASVEQA 184
Cdd:PRK06486  170 RAMGDADIVFLKNHGVMVCGPRIAEA 195
PRK09220 PRK09220
methylthioribulose 1-phosphate dehydratase;
11-184 8.80e-09

methylthioribulose 1-phosphate dehydratase;


Pssm-ID: 236415 [Multi-domain]  Cd Length: 204  Bit Score: 53.79  E-value: 8.80e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271350946  11 HQIALACRVLAARGLADGILGHISYRVKDDLILVRCRGVNERGLGyteAQDIRLVDLDGNPASAqeldGWKVPNELPLHA 90
Cdd:PRK09220    8 QQLIAAGRWIGARGWVPATSGNMSVRLDEQHCAITVSGKDKGSLT---AEDFLQVDIAGNAVPS----GRKPSAETLLHT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271350946  91 AVLRKHLEVQSVVHAHPP--TVVACDLAGIEIRpiIGAYDM----PGAK--LAAAGVPVHPRSVLIrnQRLAEEmVESMH 162
Cdd:PRK09220   81 QLYRLFPEIGAVLHTHSVnaTVLSRVEKSDALV--LEGYELqkafAGQTthETAVVVPIFDNDQDI--ARLAAR-VAPYL 155

                         170       180
                  ....*....|....*....|....*.
gi 2271350946 163 DKPVV----LLRGHGMTSAAASVEQA 184
Cdd:PRK09220  156 DAQPLrygyLIRGHGLYCWGRDMAEA 181
PRK07490 PRK07490
hypothetical protein; Provisional
 1-184 4.06e-08

hypothetical protein; Provisional


Pssm-ID: 236031 [Multi-domain]  Cd Length: 245  Bit Score: 52.41  E-value: 4.06e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271350946   1 MTLDLYQKERHQIALACRVLAARGLADGILGHISYRVKDD----LIlvrcrgvNERGLGYTEAQDIRLVDLDGNPASAQE 76
Cdd:PRK07490    3 MALSDEEQIRVDLAAAFRWIARLGMHEAVANHFSAAVSADgkqfLL-------NPKWKHFSRIRASDLLLLDADDPSTAE 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271350946  77 LDGWKVPNELPLHAAVLRKHLEVQSVVHAHPP--TVVACdLAGIEIRPIIG---------AYDM--PGAKLAAAGvpvhp 143
Cdd:PRK07490   76 RPDVPDATAWAIHGQIHRRLPHARCVMHVHSVyaTALAC-LADPTLPPIDQntarffnrvAVDTlyGGMALEEEG----- 149

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 2271350946 144 rsvlirnQRLAeemvESMHDKPVVLLRGHGMTSAAASVEQA 184
Cdd:PRK07490  150 -------ERLA----GLLGDKRRLLMGNHGVLVTGDTVAEA 179
mtnB PRK06754
methylthioribulose 1-phosphate dehydratase;
7-175 1.00e-06

methylthioribulose 1-phosphate dehydratase;


Pssm-ID: 180679 [Multi-domain]  Cd Length: 208  Bit Score: 48.12  E-value: 1.00e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271350946   7 QKERHQIALACRVLAARGLADGILGHISYRVKDDLI--LVRCRGVNERGlgyTEAQDIRLVDLDGNPASAQELdgwKVPN 84
Cdd:PRK06754    5 QRRWNELAEIKKELAARDWFPATSGNLSIKVSDDPLtfLVTASGKDKRK---TTPEDFLLVDHDGKPVEETEL---KPSA 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271350946  85 ELPLHAAVLRKhLEVQSVVHAHppTV---VACDLAG----IEIR--PIIGAYDMpGAKLAAAGVPVhprsvlIRN----Q 151
Cdd:PRK06754   79 ETLLHTHIYNN-TNAGCVLHVH--TVdnnVISELYGddgaVTFQgqEIIKALGI-WEENAEIHIPI------IENhadiP 148

                         170       180
                  ....*....|....*....|....*
gi 2271350946 152 RLAEEMVESMH-DKPVVLLRGHGMT 175
Cdd:PRK06754  149 TLAEEFAKHIQgDSGAVLIRNHGIT 173
PRK05874 PRK05874
L-fuculose-phosphate aldolase; Validated
 16-185 2.13e-06

L-fuculose-phosphate aldolase; Validated


Pssm-ID: 102036 [Multi-domain]  Cd Length: 217  Bit Score: 47.33  E-value: 2.13e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271350946  16 ACRVLAARGLADGILGHISYRVKDDLILVRCRGVNERGLgytEAQDIRLVDLDGNPASAQelDGWKVPNELPLHAAVLRK 95
Cdd:PRK05874   14 AAKDMLRRGLVEGTAGNISARRSDGNVVITPSSVDYAEM---LLHDLVLVDAGGAVLHAK--DGRSPSTELNLHLACYRA 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271350946  96 HLEVQSVVHAHPPTVVACDLAGIEIRPIIGAY------DMPGAKLAAAGVPvhprsvlirnqRLAEEMVESMHDKPVVLL 169
Cdd:PRK05874   89 FDDIGSVIHSHPVWATMFAVAHEPIPACIDEFaiycggDVRCTEYAASGTP-----------EVGRNAVRALEGRAAALI 157

                         170
                  ....*....|....*.
gi 2271350946 170 RGHGMTSAAASVEQAV 185
Cdd:PRK05874  158 ANHGLVAVGPRPDQVL 173
PRK06208 PRK06208
class II aldolase/adducin family protein;
5-215 8.79e-06

class II aldolase/adducin family protein;


Pssm-ID: 235743  Cd Length: 274  Bit Score: 45.75  E-value: 8.79e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271350946   5 LYQKERhqIALACRVLAARGLADGILGHISYRvkdDLILVRCRGVNERGL--GYTEAQDIRLVDLDGNPasaqeLDGWKV 82
Cdd:PRK06208   41 LHRKQR--LAAAFRLFARFGFDEGLAGHITAR---DPELPDHFWVNPLGVhfSQIKVSDLLLVDHDGEV-----VEGDRP 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271350946  83 PNE--LPLHAAVLRKHLEVQSVVHAH---------------PPTVVACdlAGIEIRPIIGAYdmpgaklaaAGVPVHPRS 145
Cdd:PRK06208  111 LNRaaFAIHSAIHEARPDVVAAAHTHstygkawstlgrpldPITQDAC--AFYEDHALFDDF---------TGVVVDTSE 179

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271350946 146 vlirNQRLAEemveSMHDKPVVLLRGHGMTSAAASVEQAVLQAISVNVIATLSLeIVSAGGQLQDISQED 215
Cdd:PRK06208  180 ----GRRIAA----ALGTHKAVILQNHGLLTVGPSVDAAAWWFIALERACQTQL-LAEAAGPPQPIDHET 240
PRK06357 PRK06357
hypothetical protein; Provisional
 5-107 5.86e-05

hypothetical protein; Provisional


Pssm-ID: 180541 [Multi-domain]  Cd Length: 216  Bit Score: 42.84  E-value: 5.86e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2271350946   5 LYQKERHQIALACRVLAARGLADGILGHISYRVKDDL----ILVRCRGVNERGLGYTEAQDIRLVDLDGNpasaQELDG- 79
Cdd:PRK06357    2 LFQKEREDLAKVVKTMFDRKETNAAGGNISVRMTAEKnkeyIIMTPTLMSEAKLCDLSPYQILVVDLNTG----EVIEGv 77

                          90       100
                  ....*....|....*....|....*...
gi 2271350946  80 WKVPNELPLHAAVLRKHLEVQSVVHAHP 107
Cdd:PRK06357   78 GRVTREINMHEAAYVANPKIKCVYHSHA 105
araD PRK08193
L-ribulose-5-phosphate 4-epimerase AraD;
53-125 3.48e-03

L-ribulose-5-phosphate 4-epimerase AraD;


Pssm-ID: 236181  Cd Length: 231  Bit Score: 37.51  E-value: 3.48e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2271350946  53 GLGYTE--AQDIRLVDLDGNpasaqELDGWKVPN-ELPLHAAVLRKHLEVQSVVHAHPPTVVACDLAGIEIrPIIG 125
Cdd:PRK08193   45 GVDYDKmtAEDMVVVDLEGN-----VVEGKLKPSsDTPTHLVLYKAFPEIGGIVHTHSRHATAWAQAGRDI-PALG 114
PRK03634 PRK03634
rhamnulose-1-phosphate aldolase; Provisional
 153-219 6.92e-03

rhamnulose-1-phosphate aldolase; Provisional


Pssm-ID: 179615 [Multi-domain]  Cd Length: 274  Bit Score: 36.89  E-value: 6.92e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2271350946 153 LAEEMVESMHDKPVVLLRGHGMTSAAASVEQAVLQAISVNVIATLSLEIVSAGGQLQDISQEDMAEL 219
Cdd:PRK03634  193 IGQATAEKMQKHDLVLWPKHGVFGSGPTLDEAFGLIDTAEKSAEIYVKVLSMGGMKQTITDEELIAL 259
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH