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Conserved domains on  [gi|2164597233|gb|UGS91405|]
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malonate decarboxylase subunit alpha [Ralstonia wenshanensis]

Protein Classification

acyl CoA:acetate/3-ketoacid CoA transferase( domain architecture ID 11468716)

acyl CoA:acetate/3-ketoacid CoA transferase similar to Escherichia coli acetate CoA-transferase YdiF, which has broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YdiF COG4670
Acyl CoA:acetate/3-ketoacid CoA transferase [Lipid transport and metabolism];
1-547 0e+00

Acyl CoA:acetate/3-ketoacid CoA transferase [Lipid transport and metabolism];


:

Pssm-ID: 443707 [Multi-domain]  Cd Length: 511  Bit Score: 755.03  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164597233   1 MQVITADEAARLVQPEWTVACAGFVGAGHAEAVTHALERRFLATGEPRDLTLVYSAGQGDRATRGVNHFGNPGMTRCVVG 80
Cdd:COG4670     1 SKIISAEEAAALIKDGDTVATSGFVGAGVPEELLKALEERFLETGHPRDLTLIHAAGQGDGKGRGLDHLAHEGLVKRVIG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164597233  81 GHWRSATRLADLALAEQCDAFNLPQGVLTHLYRAIAGGKPGVLTKMGLHTFVDPrteldaRYHGGAINARAKAAraagta 160
Cdd:COG4670    81 GHWGLSPKLQKLAVENKIEAYNLPQGVISHLFREIAAGRPGVLTKVGLGTFVDP------RLEGGKLNERTTED------ 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164597233 161 sWVEYERFRGEDYLFYPSFPLHCVFLRGTAADPRGNISTHEEAFHHELLAMAQAARNSGGIVIAQVRRLVDRHD-NLQAI 239
Cdd:COG4670   149 -LVELVEIDGEEYLFYKAFPIDVALIRGTTADEDGNLSMEHEALTLEVLAIAQAAKNSGGIVIAQVERIVKRGSlHPKDV 227

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164597233 240 HVPGILVDYVVVADDEtEHQMTFGEAFNPTYIrpwqGEaIQLKEDAIEASEaletsqhgaLDARTLVQRRAVLELMAqqP 319
Cdd:COG4670   228 KVPGILVDYVVVAPPE-DHMQTFSTQYNPAYS----GE-IRVPLSSLPPLP---------LDERKVIARRAAMELRP--G 290

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164597233 320 RVVNLGVGMPAAVGALAEQEGARG-FTLTVEAGPIGGTPADGLSFGASAYPEAVVDQPAQFDFYEGGGIDLAILGLAELD 398
Cdd:COG4670   291 AVVNLGIGIPEGVAAVAAEEGISDlITLTVESGPIGGVPAGGLDFGAAVNAEAIIDQPDQFDFYDGGGLDIAFLGFAQVD 370

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164597233 399 GAGNVNVSLFGeggdTVVAGVGGFINITQSARSVVFMGTLTAGGLQVEAEDGKLRIVREGRLKKIVPAVSHLTFNGEYAA 478
Cdd:COG4670   371 RHGNVNVSKFG----GRIAGCGGFINITQNAKKVVFCGTFTAGGLKVEVEDGKLRILQEGKIKKFVKKVEQITFSGKYAR 446

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2164597233 479 QSGIPVRYVTERAVFEMRDDGhgtrrLTLTEIAPGIDLQRDVLNQCAAEVAVATDLREMDARIFRRGAM 547
Cdd:COG4670   447 ERGQEVLYVTERAVFELTPEG-----LELTEIAPGIDLERDILAQMEFRPIIADDLKLMDARIFRDEPM 510
 
Name Accession Description Interval E-value
YdiF COG4670
Acyl CoA:acetate/3-ketoacid CoA transferase [Lipid transport and metabolism];
1-547 0e+00

Acyl CoA:acetate/3-ketoacid CoA transferase [Lipid transport and metabolism];


Pssm-ID: 443707 [Multi-domain]  Cd Length: 511  Bit Score: 755.03  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164597233   1 MQVITADEAARLVQPEWTVACAGFVGAGHAEAVTHALERRFLATGEPRDLTLVYSAGQGDRATRGVNHFGNPGMTRCVVG 80
Cdd:COG4670     1 SKIISAEEAAALIKDGDTVATSGFVGAGVPEELLKALEERFLETGHPRDLTLIHAAGQGDGKGRGLDHLAHEGLVKRVIG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164597233  81 GHWRSATRLADLALAEQCDAFNLPQGVLTHLYRAIAGGKPGVLTKMGLHTFVDPrteldaRYHGGAINARAKAAraagta 160
Cdd:COG4670    81 GHWGLSPKLQKLAVENKIEAYNLPQGVISHLFREIAAGRPGVLTKVGLGTFVDP------RLEGGKLNERTTED------ 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164597233 161 sWVEYERFRGEDYLFYPSFPLHCVFLRGTAADPRGNISTHEEAFHHELLAMAQAARNSGGIVIAQVRRLVDRHD-NLQAI 239
Cdd:COG4670   149 -LVELVEIDGEEYLFYKAFPIDVALIRGTTADEDGNLSMEHEALTLEVLAIAQAAKNSGGIVIAQVERIVKRGSlHPKDV 227

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164597233 240 HVPGILVDYVVVADDEtEHQMTFGEAFNPTYIrpwqGEaIQLKEDAIEASEaletsqhgaLDARTLVQRRAVLELMAqqP 319
Cdd:COG4670   228 KVPGILVDYVVVAPPE-DHMQTFSTQYNPAYS----GE-IRVPLSSLPPLP---------LDERKVIARRAAMELRP--G 290

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164597233 320 RVVNLGVGMPAAVGALAEQEGARG-FTLTVEAGPIGGTPADGLSFGASAYPEAVVDQPAQFDFYEGGGIDLAILGLAELD 398
Cdd:COG4670   291 AVVNLGIGIPEGVAAVAAEEGISDlITLTVESGPIGGVPAGGLDFGAAVNAEAIIDQPDQFDFYDGGGLDIAFLGFAQVD 370

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164597233 399 GAGNVNVSLFGeggdTVVAGVGGFINITQSARSVVFMGTLTAGGLQVEAEDGKLRIVREGRLKKIVPAVSHLTFNGEYAA 478
Cdd:COG4670   371 RHGNVNVSKFG----GRIAGCGGFINITQNAKKVVFCGTFTAGGLKVEVEDGKLRILQEGKIKKFVKKVEQITFSGKYAR 446

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2164597233 479 QSGIPVRYVTERAVFEMRDDGhgtrrLTLTEIAPGIDLQRDVLNQCAAEVAVATDLREMDARIFRRGAM 547
Cdd:COG4670   447 ERGQEVLYVTERAVFELTPEG-----LELTEIAPGIDLERDILAQMEFRPIIADDLKLMDARIFRDEPM 510
CoA_trans smart00882
Coenzyme A transferase; Coenzyme A (CoA) transferases belong to an evolutionary conserved ...
 5-250 2.54e-41

Coenzyme A transferase; Coenzyme A (CoA) transferases belong to an evolutionary conserved family of enzymes catalyzing the reversible transfer of CoA from one carboxylic acid to another. They have been identified in many prokaryotes and in mammalian tissues. The bacterial enzymes are heterodimer of two subunits (A and B) of about 25 Kd each while eukaryotic SCOT consist of a single chain which is colinear with the two bacterial subunits.


Pssm-ID: 214882 [Multi-domain]  Cd Length: 212  Bit Score: 148.12  E-value: 2.54e-41
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164597233    5 TADEAARLVQPEWTVACAGFVGAGHAEAVTHALERRFlatgePRDLTLVYSAGQGdratrGVNHFGNPGMTRCVVGGHWR 84
Cdd:smart00882   1 SAAEAAREIKDGDTVALGGFGGLPTPAALILALIRQG-----PKDLTLISENGGL-----GLGLLAGEGDVKKIIAGHVG 70

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164597233   85 SATRLADLALAEQCDAFNLPQGVLTHLYRAIAGGKPGVLTKMGLHTFVDPrteldaRYHGGAINarakaaraagtaswve 164
Cdd:smart00882  71 LTPLLGRLYFDGEIESFLLPQGGLADRLRAGAAGVPGFGTLAGLGTDVDP------RYEGGKVR---------------- 128

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164597233  165 yERFRGEDYLFYPSFPLHCVFLRGTAADPRGNISTHEEAFHHELLAMAQAARNsggiVIAQVRRLVDR---HDNLQAIHV 241
Cdd:smart00882 129 -PFGMGGAYLLVPAIRPDVALIRAHTADEFGNLVYEKEATSCGLPLTAAAAKK----VIVQVEEIVDLgvlDPDPVRLLI 203


                   ....*....
gi 2164597233  242 PGILVDYVV 250
Cdd:smart00882 204 PGVLVDAVV 212
CoA_trans pfam01144
Coenzyme A transferase;
3-252 1.66e-10

Coenzyme A transferase;


Pssm-ID: 395909 [Multi-domain]  Cd Length: 216  Bit Score: 61.16  E-value: 1.66e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164597233   3 VITADEA-ARLVQPEWTVACAGFVGAGHAEAVTHALERRFlatgePRDLTLVysagQGDRATRGVNHFGNPGMTRCVVGG 81
Cdd:pfam01144   1 VESAAEAvAKEIKDGMTVNVGGFGLIGIPETLIAALARSG-----VKDLTVI----SNEAGVLGLGPLLLNGSVKKVIAS 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164597233  82 HWRSA--TRLADLALAEQCDAFNLPQGvlTHLYRAIAGG----KPGVLTKMGLHTFVDPRTELDAryhggainarakaar 155
Cdd:pfam01144  72 YGGETanPEFGRQYFSGELEFELWPQG--GLADRLRAGGagipFEGFLTNTGIGTYVAPKKRVPG--------------- 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164597233 156 aagtaswveyerFRGEDYLFYPSFPLHCVFLRGTAADPRGNISTHEEAFHHELLAMAQAARnsggIVIAQVRRLVDRHDN 235
Cdd:pfam01144 135 ------------FGGAMYLLEPALRADVALIKASKADGEGNLVFRTTAPNFNGPAVAAAAK----VTILEVEEIVEKGEL 198

                         250
                  ....*....|....*...
gi 2164597233 236 L-QAIHVPGILVDYVVVA 252
Cdd:pfam01144 199 LpLTVHTPGVLVDAVVEA 216
 
Name Accession Description Interval E-value
YdiF COG4670
Acyl CoA:acetate/3-ketoacid CoA transferase [Lipid transport and metabolism];
1-547 0e+00

Acyl CoA:acetate/3-ketoacid CoA transferase [Lipid transport and metabolism];


Pssm-ID: 443707 [Multi-domain]  Cd Length: 511  Bit Score: 755.03  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164597233   1 MQVITADEAARLVQPEWTVACAGFVGAGHAEAVTHALERRFLATGEPRDLTLVYSAGQGDRATRGVNHFGNPGMTRCVVG 80
Cdd:COG4670     1 SKIISAEEAAALIKDGDTVATSGFVGAGVPEELLKALEERFLETGHPRDLTLIHAAGQGDGKGRGLDHLAHEGLVKRVIG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164597233  81 GHWRSATRLADLALAEQCDAFNLPQGVLTHLYRAIAGGKPGVLTKMGLHTFVDPrteldaRYHGGAINARAKAAraagta 160
Cdd:COG4670    81 GHWGLSPKLQKLAVENKIEAYNLPQGVISHLFREIAAGRPGVLTKVGLGTFVDP------RLEGGKLNERTTED------ 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164597233 161 sWVEYERFRGEDYLFYPSFPLHCVFLRGTAADPRGNISTHEEAFHHELLAMAQAARNSGGIVIAQVRRLVDRHD-NLQAI 239
Cdd:COG4670   149 -LVELVEIDGEEYLFYKAFPIDVALIRGTTADEDGNLSMEHEALTLEVLAIAQAAKNSGGIVIAQVERIVKRGSlHPKDV 227

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164597233 240 HVPGILVDYVVVADDEtEHQMTFGEAFNPTYIrpwqGEaIQLKEDAIEASEaletsqhgaLDARTLVQRRAVLELMAqqP 319
Cdd:COG4670   228 KVPGILVDYVVVAPPE-DHMQTFSTQYNPAYS----GE-IRVPLSSLPPLP---------LDERKVIARRAAMELRP--G 290

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164597233 320 RVVNLGVGMPAAVGALAEQEGARG-FTLTVEAGPIGGTPADGLSFGASAYPEAVVDQPAQFDFYEGGGIDLAILGLAELD 398
Cdd:COG4670   291 AVVNLGIGIPEGVAAVAAEEGISDlITLTVESGPIGGVPAGGLDFGAAVNAEAIIDQPDQFDFYDGGGLDIAFLGFAQVD 370

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164597233 399 GAGNVNVSLFGeggdTVVAGVGGFINITQSARSVVFMGTLTAGGLQVEAEDGKLRIVREGRLKKIVPAVSHLTFNGEYAA 478
Cdd:COG4670   371 RHGNVNVSKFG----GRIAGCGGFINITQNAKKVVFCGTFTAGGLKVEVEDGKLRILQEGKIKKFVKKVEQITFSGKYAR 446

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2164597233 479 QSGIPVRYVTERAVFEMRDDGhgtrrLTLTEIAPGIDLQRDVLNQCAAEVAVATDLREMDARIFRRGAM 547
Cdd:COG4670   447 ERGQEVLYVTERAVFELTPEG-----LELTEIAPGIDLERDILAQMEFRPIIADDLKLMDARIFRDEPM 510
CoA_trans smart00882
Coenzyme A transferase; Coenzyme A (CoA) transferases belong to an evolutionary conserved ...
 5-250 2.54e-41

Coenzyme A transferase; Coenzyme A (CoA) transferases belong to an evolutionary conserved family of enzymes catalyzing the reversible transfer of CoA from one carboxylic acid to another. They have been identified in many prokaryotes and in mammalian tissues. The bacterial enzymes are heterodimer of two subunits (A and B) of about 25 Kd each while eukaryotic SCOT consist of a single chain which is colinear with the two bacterial subunits.


Pssm-ID: 214882 [Multi-domain]  Cd Length: 212  Bit Score: 148.12  E-value: 2.54e-41
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164597233    5 TADEAARLVQPEWTVACAGFVGAGHAEAVTHALERRFlatgePRDLTLVYSAGQGdratrGVNHFGNPGMTRCVVGGHWR 84
Cdd:smart00882   1 SAAEAAREIKDGDTVALGGFGGLPTPAALILALIRQG-----PKDLTLISENGGL-----GLGLLAGEGDVKKIIAGHVG 70

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164597233   85 SATRLADLALAEQCDAFNLPQGVLTHLYRAIAGGKPGVLTKMGLHTFVDPrteldaRYHGGAINarakaaraagtaswve 164
Cdd:smart00882  71 LTPLLGRLYFDGEIESFLLPQGGLADRLRAGAAGVPGFGTLAGLGTDVDP------RYEGGKVR---------------- 128

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164597233  165 yERFRGEDYLFYPSFPLHCVFLRGTAADPRGNISTHEEAFHHELLAMAQAARNsggiVIAQVRRLVDR---HDNLQAIHV 241
Cdd:smart00882 129 -PFGMGGAYLLVPAIRPDVALIRAHTADEFGNLVYEKEATSCGLPLTAAAAKK----VIVQVEEIVDLgvlDPDPVRLLI 203


                   ....*....
gi 2164597233  242 PGILVDYVV 250
Cdd:smart00882 204 PGVLVDAVV 212
AtoA COG2057
Acyl-CoA:acetate/3-ketoacid CoA transferase, beta subunit [Lipid transport and metabolism];
321-539 1.54e-26

Acyl-CoA:acetate/3-ketoacid CoA transferase, beta subunit [Lipid transport and metabolism];


Pssm-ID: 441660  Cd Length: 235  Bit Score: 107.94  E-value: 1.54e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164597233 321 VVNLGVGMPAAVGALAEQEGARGFTLTVEAGPIGGTPA-------DGLSFGASaypEAVVDQPAQFDFYEGGGIDLAILG 393
Cdd:COG2057    21 VVNLGIGLPTLAANLAPLTHAPDVTLQSENGLLGPGPAplpgsvgDPDLINAG---KQFFDSADSFAMIRGGHIDVGFLG 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164597233 394 LAELDGAGNVNVSLFG--EGGDTVVAGVGGFINITQSARSVVFMGTLTAgglqveaedgklrivregrlKKIVPAVSHLT 471
Cdd:COG2057    98 AAQVDRYGNLNNWMIGdyDKPGKRLPGMGGAMDLAAGAKRVIVVMEHSK--------------------RKFVEKCDLLT 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2164597233 472 FNGEYAAqsgiPVRYVTERAVFEMRDDGhgtrRLTLTEIAPGIDLQrDVLNQCAAEVAVATDLREMDA 539
Cdd:COG2057   158 GPGVVDG----PRRVITDLAVFDFDPEK----GLVLRELHPGVTVE-EVQENTGFELIVADDVPETPP 216
AtoD COG1788
Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid transport and metabolism];
1-252 1.34e-13

Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid transport and metabolism];


Pssm-ID: 441394  Cd Length: 226  Bit Score: 70.11  E-value: 1.34e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164597233   1 MQVITADEAARLVQPEWTVACAGFVGAGHAEAVTHALERRflatgEPRDLTLV-YSAGQGD-----RAtrgvnhfgnpGM 74
Cdd:COG1788     3 KVVISLAEAVADVKDGMTIAIGGFGLCGIPMALIDELIRQ-----GVKDLTLIsNNAGVDGlglliGA----------GQ 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164597233  75 TRCVVGGHWR---SATRLADLALAEQCDAFNLPQGVLTHLYRAIAGGKPGVLTKMGLHTFVdprteldARYHggainara 151
Cdd:COG1788    68 VKKVIASYVGgvgLNPEFRRAVEAGELEVELVPQGTLAERLRAGGAGLPFFPTRTGLGTDV-------AEGK-------- 132

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164597233 152 kaaraagtaswvEYERFRGEDYLFYPSFPLHCVFLRGTAADPRGNIsTHEEAFHHELLAMAQAARnsggIVIAQVRRLVD 231
Cdd:COG1788   133 ------------ETREIDGEEYVLEPALRADVALIHAQKADRAGNL-VYRGTARNFNPLMAMAAK----RVIVEVEEIVE 195

                         250       260
                  ....*....|....*....|...
gi 2164597233 232 rHDNL--QAIHVPGILVDYVVVA 252
Cdd:COG1788   196 -VGELdpDAVVTPGIFVDAVVEV 217
CoA_trans pfam01144
Coenzyme A transferase;
3-252 1.66e-10

Coenzyme A transferase;


Pssm-ID: 395909 [Multi-domain]  Cd Length: 216  Bit Score: 61.16  E-value: 1.66e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164597233   3 VITADEA-ARLVQPEWTVACAGFVGAGHAEAVTHALERRFlatgePRDLTLVysagQGDRATRGVNHFGNPGMTRCVVGG 81
Cdd:pfam01144   1 VESAAEAvAKEIKDGMTVNVGGFGLIGIPETLIAALARSG-----VKDLTVI----SNEAGVLGLGPLLLNGSVKKVIAS 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164597233  82 HWRSA--TRLADLALAEQCDAFNLPQGvlTHLYRAIAGG----KPGVLTKMGLHTFVDPRTELDAryhggainarakaar 155
Cdd:pfam01144  72 YGGETanPEFGRQYFSGELEFELWPQG--GLADRLRAGGagipFEGFLTNTGIGTYVAPKKRVPG--------------- 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164597233 156 aagtaswveyerFRGEDYLFYPSFPLHCVFLRGTAADPRGNISTHEEAFHHELLAMAQAARnsggIVIAQVRRLVDRHDN 235
Cdd:pfam01144 135 ------------FGGAMYLLEPALRADVALIKASKADGEGNLVFRTTAPNFNGPAVAAAAK----VTILEVEEIVEKGEL 198

                         250
                  ....*....|....*...
gi 2164597233 236 L-QAIHVPGILVDYVVVA 252
Cdd:pfam01144 199 LpLTVHTPGVLVDAVVEA 216
CoA_trans smart00882
Coenzyme A transferase; Coenzyme A (CoA) transferases belong to an evolutionary conserved ...
 321-520 1.10e-04

Coenzyme A transferase; Coenzyme A (CoA) transferases belong to an evolutionary conserved family of enzymes catalyzing the reversible transfer of CoA from one carboxylic acid to another. They have been identified in many prokaryotes and in mammalian tissues. The bacterial enzymes are heterodimer of two subunits (A and B) of about 25 Kd each while eukaryotic SCOT consist of a single chain which is colinear with the two bacterial subunits.


Pssm-ID: 214882 [Multi-domain]  Cd Length: 212  Bit Score: 43.73  E-value: 1.10e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164597233  321 VVNLGVGMP-----AAVGALAEQeGARGFTLTVEAGPIG-GTPADGLSFG---ASAYPEAVVDQPAQFD-----FY--EG 384
Cdd:smart00882  14 TVALGGFGGlptpaALILALIRQ-GPKDLTLISENGGLGlGLLAGEGDVKkiiAGHVGLTPLLGRLYFDgeiesFLlpQG 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2164597233  385 GGIDLAILGLAELDGAGNVN-----VSLFGEGGDTVVAGVGG-FINITQSARSVVFMGTLTAGglqveaEDGKLRIVREG 458
Cdd:smart00882  93 GLADRLRAGAAGVPGFGTLAglgtdVDPRYEGGKVRPFGMGGaYLLVPAIRPDVALIRAHTAD------EFGNLVYEKEA 166

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2164597233  459 RlkkivpavsHLTFN--GEYAAQSGIPVRYVTERAVFEMRDDGHgtrrltlteIAPGIDLQRDV 520
Cdd:smart00882 167 T---------SCGLPltAAAAKKVIVQVEEIVDLGVLDPDPVRL---------LIPGVLVDAVV 212
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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