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Conserved domains on  [gi|2156602196|gb|UFN56798|]
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NAD(P)H-hydrate dehydratase [Microbulbifer celer]

Protein Classification

carbohydrate kinase family protein( domain architecture ID 1008582)

carbohydrate kinase family protein similar to bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, allowing the repair of both epimers of NAD(P)HX

CATH:  3.40.1190.20|3.40.50.10260
EC:  5.1.99.6
Gene Ontology:  GO:0005524|GO:0052857
PubMed:  21994945

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
PRK10565 super family cl32537
putative carbohydrate kinase; Provisional
 7-502 3.36e-115

putative carbohydrate kinase; Provisional


The actual alignment was detected with superfamily member PRK10565:

Pssm-ID: 182554 [Multi-domain]  Cd Length: 508  Bit Score: 349.36  E-value: 3.36e-115
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196   7 TGATAPQKLYTAAAVQELDRLLISQQQIPGLTLMKRAGRAAFDRLRAHWPEVNRIQVFCGGGNNGGDGYVIAGLAAQRKL 86
Cdd:PRK10565    9 NPVSIPHSVWPADDIRRGEREAADALGLTLYELMLRAGEAAFQVARSAYPDARHWLVLCGHGNNGGDGYVVARLAQAAGI 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196  87 PVVVYTAVSPEKLTGDALEAyRFAEREGATMVSDlAELSTADGNAVLVDALLGTGFSGELRAPVDTAVAHINASAAPVLA 166
Cdd:PRK10565   89 DVTLLAQESDKPLPEEAALA-REAWLNAGGEIHA-ADIVWPESVDLIVDALLGTGLRQAPREPYAALIDQANAHPAPVVA 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 167 VDIPSGLNADSGAA-GEAVQADLTVTFIGRKTGLYLGRGPALTGEVIFDDLSASDTVYHKvPAHLHRFDGGSLEQ-LPVR 244
Cdd:PRK10565  167 LDIPSGLLAETGATpGAVINADHTVTFIALKPGLLTGKARDVVGQLHFDSLGLDSWLAGQ-EAPIQRFDAEQLSQwLKPR 245

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 245 AADSYKNQFGHVMVVGGDHGYGGAALMASEAAARAGAGLVSLASRPEHVAAALTRCPEVMARPVvSGQELEPLLELPSVI 324
Cdd:PRK10565  246 RPTSHKGDHGRLLIIGGDHGTAGAIRMAGEAALRSGAGLVRVLTRSENIAPLLTARPELMVHEL-TPDSLEESLEWADVV 324

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 325 AVGPGLGQSPWSEQLLARAGRTEAALVLDADALNILAggrvLAGVQRDDWVLTPHIGEAARLLNTSKAEVVTDPVAAARA 404
Cdd:PRK10565  325 VIGPGLGQQEWGKKALQKVENFRKPMLWDADALNLLA----INPDKRHNRVITPHPGEAARLLGCSVAEIESDRLLSARR 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 405 IQQKFSGVVILKGAGTLIA-HADGVDLINSGNPGMASGGMGDLLTGVIAALIAQGMTLPAAARLAVWLHGEAGNRAAAEG 483
Cdd:PRK10565  401 LVKRYGGVVVLKGAGTVIAaEPDALAIIDVGNAGMASGGMGDVLSGIIGALLGQKLSPYDAACAGCVAHGAAADVLAARF 480

                         490
                  ....*....|....*....
gi 2156602196 484 GQRGLLATDLLSHIRRLVD 502
Cdd:PRK10565  481 GTRGMLATDLFSTLQRIVN 499
 
Name Accession Description Interval E-value
PRK10565 PRK10565
putative carbohydrate kinase; Provisional
 7-502 3.36e-115

putative carbohydrate kinase; Provisional


Pssm-ID: 182554 [Multi-domain]  Cd Length: 508  Bit Score: 349.36  E-value: 3.36e-115
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196   7 TGATAPQKLYTAAAVQELDRLLISQQQIPGLTLMKRAGRAAFDRLRAHWPEVNRIQVFCGGGNNGGDGYVIAGLAAQRKL 86
Cdd:PRK10565    9 NPVSIPHSVWPADDIRRGEREAADALGLTLYELMLRAGEAAFQVARSAYPDARHWLVLCGHGNNGGDGYVVARLAQAAGI 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196  87 PVVVYTAVSPEKLTGDALEAyRFAEREGATMVSDlAELSTADGNAVLVDALLGTGFSGELRAPVDTAVAHINASAAPVLA 166
Cdd:PRK10565   89 DVTLLAQESDKPLPEEAALA-REAWLNAGGEIHA-ADIVWPESVDLIVDALLGTGLRQAPREPYAALIDQANAHPAPVVA 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 167 VDIPSGLNADSGAA-GEAVQADLTVTFIGRKTGLYLGRGPALTGEVIFDDLSASDTVYHKvPAHLHRFDGGSLEQ-LPVR 244
Cdd:PRK10565  167 LDIPSGLLAETGATpGAVINADHTVTFIALKPGLLTGKARDVVGQLHFDSLGLDSWLAGQ-EAPIQRFDAEQLSQwLKPR 245

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 245 AADSYKNQFGHVMVVGGDHGYGGAALMASEAAARAGAGLVSLASRPEHVAAALTRCPEVMARPVvSGQELEPLLELPSVI 324
Cdd:PRK10565  246 RPTSHKGDHGRLLIIGGDHGTAGAIRMAGEAALRSGAGLVRVLTRSENIAPLLTARPELMVHEL-TPDSLEESLEWADVV 324

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 325 AVGPGLGQSPWSEQLLARAGRTEAALVLDADALNILAggrvLAGVQRDDWVLTPHIGEAARLLNTSKAEVVTDPVAAARA 404
Cdd:PRK10565  325 VIGPGLGQQEWGKKALQKVENFRKPMLWDADALNLLA----INPDKRHNRVITPHPGEAARLLGCSVAEIESDRLLSARR 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 405 IQQKFSGVVILKGAGTLIA-HADGVDLINSGNPGMASGGMGDLLTGVIAALIAQGMTLPAAARLAVWLHGEAGNRAAAEG 483
Cdd:PRK10565  401 LVKRYGGVVVLKGAGTVIAaEPDALAIIDVGNAGMASGGMGDVLSGIIGALLGQKLSPYDAACAGCVAHGAAADVLAARF 480

                         490
                  ....*....|....*....
gi 2156602196 484 GQRGLLATDLLSHIRRLVD 502
Cdd:PRK10565  481 GTRGMLATDLFSTLQRIVN 499
Nnr2 COG0063
NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain [Nucleotide transport ...
 241-501 2.02e-89

NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain [Nucleotide transport and metabolism];


Pssm-ID: 439833  Cd Length: 280  Bit Score: 275.08  E-value: 2.02e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 241 LPVRAADSYKNQFGHVMVVGGDHGYGGAALMASEAAARAGAGLVSLASRPEHVAAALTRCPEVMARPVVSGQELEPLLEL 320
Cdd:COG0063    14 LPPRPPDSHKGSRGHVLVIGGSRGYPGAAVLAARAALRAGAGLVTVAVPESAAPAVAAALPELMVIPLPEEDELLELLER 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 321 PSVIAVGPGLGQSPWSEQLLARA-GRTEAALVLDADALNILAGGRVLAGVQRDDWVLTPHIGEAARLLNTSKAEVVTDPV 399
Cdd:COG0063    94 ADAVVIGPGLGRDEETRELLRALlEAADKPLVLDADALNLLAEDPELLAALPAPTVLTPHPGEFARLLGCSVAEIQADRL 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 400 AAARAIQQKFSGVVILKGAGTLIAHADGVDLIN-SGNPGMASGGMGDLLTGVIAALIAQGMTLPAAARLAVWLHGEAGNR 478
Cdd:COG0063   174 EAAREAAKRYGAVVVLKGAGTVIAAPDGRVYINpTGNPGLATAGSGDVLAGIIAGLLAQGLDPFEAAAAGVYLHGLAGDL 253

                         250       260
                  ....*....|....*....|...
gi 2156602196 479 AAAEGGqRGLLATDLLSHIRRLV 501
Cdd:COG0063   254 AAEERG-RGLLASDLIEALPAAL 275
YXKO-related cd01171
B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of ...
 246-498 3.05e-73

B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily.


Pssm-ID: 238576  Cd Length: 254  Bit Score: 232.50  E-value: 3.05e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 246 ADSYKNQFGHVMVVGGDHGYGGAALMASEAAARAGAGLVSLASRPEHVAAALTRCPEVMARPV--VSGQELEPLLELPSV 323
Cdd:cd01171     1 PDSHKGSRGRVLVIGGSRGYTGAAYLAALAALRAGAGLVTVATPPEAAAVIKSYSPELMVHPLleTDIEELLELLERADA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 324 IAVGPGLGQSPWSEQLLARAGRTEAALVLDADALNILAGGRVLAgVQRDDWVLTPHIGEAARLLNTSKAEVVTDPVAAAR 403
Cdd:cd01171    81 VVIGPGLGRDEEAAEILEKALAKDKPLVLDADALNLLADEPSLI-KRYGPVVLTPHPGEFARLLGALVEEIQADRLAAAR 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 404 AIQQKFSGVVILKGAGTLIAHADGVDLINS-GNPGMASGGMGDLLTGVIAALIAQGMTLPAAARLAVWLHGEAGNRAAAE 482
Cdd:cd01171   160 EAAAKLGATVVLKGAVTVIADPDGRVYVNPtGNPGLATGGSGDVLAGIIAALLAQGLSPLEAAALAVYLHGLAGDLAAKK 239

                         250
                  ....*....|....*.
gi 2156602196 483 GGqRGLLATDLLSHIR 498
Cdd:cd01171   240 KG-AGLTAADLVAEIP 254
yjeF_cterm TIGR00196
yjeF C-terminal region, hydroxyethylthiazole kinase-related; E. coli yjeF has full-length ...
 236-502 1.56e-53

yjeF C-terminal region, hydroxyethylthiazole kinase-related; E. coli yjeF has full-length orthologs in a number of species, all of unknown function. However, yeast YNL200C is homologous and corresponds to the N-terminal region while yeast YKL151C and B. subtilis yxkO correspond to this C-terminal region only. The present model may hit hydroxyethylthiazole kinase, an enzyme associated with thiamine biosynthesis. [Unknown function, General]


Pssm-ID: 272955  Cd Length: 270  Bit Score: 181.43  E-value: 1.56e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 236 GSLEQLPVRAADSYKNQFGHVMVVGGDHGYGGAALMASEAAARAGAGLVSLASRPEHVAAALTRCPEVMARPV-VSGQEL 314
Cdd:TIGR00196   7 GDLLTLPLRDPNSHKGQYGRVLIIGGSDDYSGAPLLAALAALRAGAGLVTVAAPENVITLINSVSPELIVHRLmWKVDED 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 315 EPLLELPSVIAVGPGLGQSPWSEQLLARAGRTEAALVLDADALNILAGGRVLAGvqrdDWVLTPHIGEAARLLNtsKAEV 394
Cdd:TIGR00196  87 EELLERYDVVVIGPGLGQDPSFKKAVEEVLELDKPVVLDADALNLLTYNQKREG----EVILTPHPGEFKRLLG--VNEI 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 395 VTDPVAAARAIQQKFSGVVILKGAGTLIAHADGVDLINS-GNPGMASGGMGDLLTGVIAALIAQGMTLPAAARLAVWLHG 473
Cdd:TIGR00196 161 QGDRLEAAQDIAQKLQAVVVLKGAADVIAAPDGDLWINKtGNAALAKGGTGDVLAGLIGGLLAQNLDPFDAACNAAFAHG 240

                         250       260
                  ....*....|....*....|....*....
gi 2156602196 474 EAGNRAAAEGGQRGLLATDLLSHIRRLVD 502
Cdd:TIGR00196 241 LAGDLALKNHGAYGLTALDLIEKIPRVCK 269
Carb_kinase pfam01256
Carbohydrate kinase; This family is related to pfam02110 and pfam00294 implying that it also ...
 256-499 7.06e-45

Carbohydrate kinase; This family is related to pfam02110 and pfam00294 implying that it also is a carbohydrate kinase. (personal obs Yeats C).


Pssm-ID: 396007  Cd Length: 242  Bit Score: 157.53  E-value: 7.06e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 256 VMVVGGDHGYGGAALMASEAAARAGAGLVSLASRPEHVAAALTRCPEVMARPVVSGQELEPLLELPSVIAVGPGLGQSPW 335
Cdd:pfam01256   1 VLVIGGSKDYTGAPLLAALAALRSGAGLVSVATDSEAIAVLKSPLPEVMVHPLPETSSILEKLSRYDAVVIGPGLGRDEK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 336 SEQLLARAGRTEAALVLDADALNILAGGRVLAGvQRDDWVLTPHIGEAARLLNTSKAeVVTDPVAAARAIQQKFSGVVIL 415
Cdd:pfam01256  81 GKAALEEVLAKDCPLVIDADALNLLAINNEKPA-REGPTVLTPHPGEFERLCGLAGI-LGDDRLEAARELAQKLNGTILL 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 416 KGAGTLIA-HADGVDLINSGNPGMASGGMGDLLTGVIAALIAQGMTLPAAARLAVWLHGEAGNRAAAEGGqRGLLATDLL 494
Cdd:pfam01256 159 KGNVTVIAaPGGEVWINSTGNSALAKGGSGDVLAGLIGGLLAQNEDPYDAAIAAAWLHGAASDLAAENHG-VYMLPTLLS 237


                  ....*
gi 2156602196 495 SHIRR 499
Cdd:pfam01256 238 KIIPR 242
 
Name Accession Description Interval E-value
PRK10565 PRK10565
putative carbohydrate kinase; Provisional
 7-502 3.36e-115

putative carbohydrate kinase; Provisional


Pssm-ID: 182554 [Multi-domain]  Cd Length: 508  Bit Score: 349.36  E-value: 3.36e-115
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196   7 TGATAPQKLYTAAAVQELDRLLISQQQIPGLTLMKRAGRAAFDRLRAHWPEVNRIQVFCGGGNNGGDGYVIAGLAAQRKL 86
Cdd:PRK10565    9 NPVSIPHSVWPADDIRRGEREAADALGLTLYELMLRAGEAAFQVARSAYPDARHWLVLCGHGNNGGDGYVVARLAQAAGI 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196  87 PVVVYTAVSPEKLTGDALEAyRFAEREGATMVSDlAELSTADGNAVLVDALLGTGFSGELRAPVDTAVAHINASAAPVLA 166
Cdd:PRK10565   89 DVTLLAQESDKPLPEEAALA-REAWLNAGGEIHA-ADIVWPESVDLIVDALLGTGLRQAPREPYAALIDQANAHPAPVVA 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 167 VDIPSGLNADSGAA-GEAVQADLTVTFIGRKTGLYLGRGPALTGEVIFDDLSASDTVYHKvPAHLHRFDGGSLEQ-LPVR 244
Cdd:PRK10565  167 LDIPSGLLAETGATpGAVINADHTVTFIALKPGLLTGKARDVVGQLHFDSLGLDSWLAGQ-EAPIQRFDAEQLSQwLKPR 245

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 245 AADSYKNQFGHVMVVGGDHGYGGAALMASEAAARAGAGLVSLASRPEHVAAALTRCPEVMARPVvSGQELEPLLELPSVI 324
Cdd:PRK10565  246 RPTSHKGDHGRLLIIGGDHGTAGAIRMAGEAALRSGAGLVRVLTRSENIAPLLTARPELMVHEL-TPDSLEESLEWADVV 324

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 325 AVGPGLGQSPWSEQLLARAGRTEAALVLDADALNILAggrvLAGVQRDDWVLTPHIGEAARLLNTSKAEVVTDPVAAARA 404
Cdd:PRK10565  325 VIGPGLGQQEWGKKALQKVENFRKPMLWDADALNLLA----INPDKRHNRVITPHPGEAARLLGCSVAEIESDRLLSARR 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 405 IQQKFSGVVILKGAGTLIA-HADGVDLINSGNPGMASGGMGDLLTGVIAALIAQGMTLPAAARLAVWLHGEAGNRAAAEG 483
Cdd:PRK10565  401 LVKRYGGVVVLKGAGTVIAaEPDALAIIDVGNAGMASGGMGDVLSGIIGALLGQKLSPYDAACAGCVAHGAAADVLAARF 480

                         490
                  ....*....|....*....
gi 2156602196 484 GQRGLLATDLLSHIRRLVD 502
Cdd:PRK10565  481 GTRGMLATDLFSTLQRIVN 499
Nnr2 COG0063
NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain [Nucleotide transport ...
 241-501 2.02e-89

NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain [Nucleotide transport and metabolism];


Pssm-ID: 439833  Cd Length: 280  Bit Score: 275.08  E-value: 2.02e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 241 LPVRAADSYKNQFGHVMVVGGDHGYGGAALMASEAAARAGAGLVSLASRPEHVAAALTRCPEVMARPVVSGQELEPLLEL 320
Cdd:COG0063    14 LPPRPPDSHKGSRGHVLVIGGSRGYPGAAVLAARAALRAGAGLVTVAVPESAAPAVAAALPELMVIPLPEEDELLELLER 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 321 PSVIAVGPGLGQSPWSEQLLARA-GRTEAALVLDADALNILAGGRVLAGVQRDDWVLTPHIGEAARLLNTSKAEVVTDPV 399
Cdd:COG0063    94 ADAVVIGPGLGRDEETRELLRALlEAADKPLVLDADALNLLAEDPELLAALPAPTVLTPHPGEFARLLGCSVAEIQADRL 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 400 AAARAIQQKFSGVVILKGAGTLIAHADGVDLIN-SGNPGMASGGMGDLLTGVIAALIAQGMTLPAAARLAVWLHGEAGNR 478
Cdd:COG0063   174 EAAREAAKRYGAVVVLKGAGTVIAAPDGRVYINpTGNPGLATAGSGDVLAGIIAGLLAQGLDPFEAAAAGVYLHGLAGDL 253

                         250       260
                  ....*....|....*....|...
gi 2156602196 479 AAAEGGqRGLLATDLLSHIRRLV 501
Cdd:COG0063   254 AAEERG-RGLLASDLIEALPAAL 275
Nnr1 COG0062
NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate epimerase domain [Nucleotide transport and ...
 14-501 2.26e-80

NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate epimerase domain [Nucleotide transport and metabolism];


Pssm-ID: 439832 [Multi-domain]  Cd Length: 499  Bit Score: 259.03  E-value: 2.26e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196  14 KLYTAAAVQELDRLLISQQQIPGLTLMKRAGRAAFDRLRAHWP-EVNRIQVFCgggnnggdgYVIAGLAAQRKLPVVVYT 92
Cdd:COG0062     2 KLLTAAQMRALDRAAIEALGIPGLVLMERAGRAVARAIRRRFPsAARRVLVLCgpgnnggdgLVAARLLAEAGYNVTVFL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196  93 AVSPEKLTGDALEAYRFAEREGATMVSDLAELSTADGNAVLVDALLGTGFSGELRAPVDTAVAHINASAAPVLAVDIPSG 172
Cdd:COG0062    82 LGDPEKLSGDAAANLERLKAAGIPILELDDELPELAEADLIVDALFGTGLSRPLRGPYAELIEAINASGAPVLAVDIPSG 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 173 LNADSGAA-GEAVQADLTVTFIGRKTGLYLGRGPALTGEVIFDDLSASDTVYHKVPAHLHRFDGGSLEQLPVRAADSYKN 251
Cdd:COG0062   162 LDADTGEVlGAAVRADLTVTFGAPKPGLLLGPGRDYCGELVVADIGIGIPAAAEAPAALLLLADLLALLLPPRRRSHHKG 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 252 QFGHVMVVGGDHGYGGAALMASEAAARAGAGLVSLASRPEHVAAALTRCPEVMARPVVSGQELEPLLELPSVIAVGPGLG 331
Cdd:COG0062   242 GGGGVLVIGGGGGGGGAAAAAAAAAAAAGGGLVVLAVPPAAAAALLAALPEAMALALDDDEELLLLLAAAVVVAGGGGGG 321

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 332 QSPWSEQLLARAGRTEAALVLDADALNILAggrvLAGVQRDDWVLTPHIGEAARLLNTSKAEVVTDPVAAARAIQQKFSG 411
Cdd:COG0062   322 GGGAGGGLLLLLLLLLLLLVLLAAALLLLL----ALAAALLLLLLLPPPLAAALLLLRLLTELLELRAAAAALLAAAAAA 397

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 412 VVILKGAGTLIAHADGVDLINSGNPGMASGGMGDLLTGVIAALIAQGMTLPAAARLAVWLHGEAGNRAAAEGGQRGLLAT 491
Cdd:COG0062   398 AAVAAAAVVAGAAGVVVVAAAGGGGGGGGGGGGGGGGGGGGGGGGGGGLLAGAAAAAAAAAAAAAAAAAAAAAAAALAAA 477

                         490
                  ....*....|
gi 2156602196 492 DLLSHIRRLV 501
Cdd:COG0062   478 LLAAAAALIA 487
YXKO-related cd01171
B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of ...
 246-498 3.05e-73

B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily.


Pssm-ID: 238576  Cd Length: 254  Bit Score: 232.50  E-value: 3.05e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 246 ADSYKNQFGHVMVVGGDHGYGGAALMASEAAARAGAGLVSLASRPEHVAAALTRCPEVMARPV--VSGQELEPLLELPSV 323
Cdd:cd01171     1 PDSHKGSRGRVLVIGGSRGYTGAAYLAALAALRAGAGLVTVATPPEAAAVIKSYSPELMVHPLleTDIEELLELLERADA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 324 IAVGPGLGQSPWSEQLLARAGRTEAALVLDADALNILAGGRVLAgVQRDDWVLTPHIGEAARLLNTSKAEVVTDPVAAAR 403
Cdd:cd01171    81 VVIGPGLGRDEEAAEILEKALAKDKPLVLDADALNLLADEPSLI-KRYGPVVLTPHPGEFARLLGALVEEIQADRLAAAR 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 404 AIQQKFSGVVILKGAGTLIAHADGVDLINS-GNPGMASGGMGDLLTGVIAALIAQGMTLPAAARLAVWLHGEAGNRAAAE 482
Cdd:cd01171   160 EAAAKLGATVVLKGAVTVIADPDGRVYVNPtGNPGLATGGSGDVLAGIIAALLAQGLSPLEAAALAVYLHGLAGDLAAKK 239

                         250
                  ....*....|....*.
gi 2156602196 483 GGqRGLLATDLLSHIR 498
Cdd:cd01171   240 KG-AGLTAADLVAEIP 254
yjeF_cterm TIGR00196
yjeF C-terminal region, hydroxyethylthiazole kinase-related; E. coli yjeF has full-length ...
 236-502 1.56e-53

yjeF C-terminal region, hydroxyethylthiazole kinase-related; E. coli yjeF has full-length orthologs in a number of species, all of unknown function. However, yeast YNL200C is homologous and corresponds to the N-terminal region while yeast YKL151C and B. subtilis yxkO correspond to this C-terminal region only. The present model may hit hydroxyethylthiazole kinase, an enzyme associated with thiamine biosynthesis. [Unknown function, General]


Pssm-ID: 272955  Cd Length: 270  Bit Score: 181.43  E-value: 1.56e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 236 GSLEQLPVRAADSYKNQFGHVMVVGGDHGYGGAALMASEAAARAGAGLVSLASRPEHVAAALTRCPEVMARPV-VSGQEL 314
Cdd:TIGR00196   7 GDLLTLPLRDPNSHKGQYGRVLIIGGSDDYSGAPLLAALAALRAGAGLVTVAAPENVITLINSVSPELIVHRLmWKVDED 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 315 EPLLELPSVIAVGPGLGQSPWSEQLLARAGRTEAALVLDADALNILAGGRVLAGvqrdDWVLTPHIGEAARLLNtsKAEV 394
Cdd:TIGR00196  87 EELLERYDVVVIGPGLGQDPSFKKAVEEVLELDKPVVLDADALNLLTYNQKREG----EVILTPHPGEFKRLLG--VNEI 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 395 VTDPVAAARAIQQKFSGVVILKGAGTLIAHADGVDLINS-GNPGMASGGMGDLLTGVIAALIAQGMTLPAAARLAVWLHG 473
Cdd:TIGR00196 161 QGDRLEAAQDIAQKLQAVVVLKGAADVIAAPDGDLWINKtGNAALAKGGTGDVLAGLIGGLLAQNLDPFDAACNAAFAHG 240

                         250       260
                  ....*....|....*....|....*....
gi 2156602196 474 EAGNRAAAEGGQRGLLATDLLSHIRRLVD 502
Cdd:TIGR00196 241 LAGDLALKNHGAYGLTALDLIEKIPRVCK 269
Carb_kinase pfam01256
Carbohydrate kinase; This family is related to pfam02110 and pfam00294 implying that it also ...
 256-499 7.06e-45

Carbohydrate kinase; This family is related to pfam02110 and pfam00294 implying that it also is a carbohydrate kinase. (personal obs Yeats C).


Pssm-ID: 396007  Cd Length: 242  Bit Score: 157.53  E-value: 7.06e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 256 VMVVGGDHGYGGAALMASEAAARAGAGLVSLASRPEHVAAALTRCPEVMARPVVSGQELEPLLELPSVIAVGPGLGQSPW 335
Cdd:pfam01256   1 VLVIGGSKDYTGAPLLAALAALRSGAGLVSVATDSEAIAVLKSPLPEVMVHPLPETSSILEKLSRYDAVVIGPGLGRDEK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 336 SEQLLARAGRTEAALVLDADALNILAGGRVLAGvQRDDWVLTPHIGEAARLLNTSKAeVVTDPVAAARAIQQKFSGVVIL 415
Cdd:pfam01256  81 GKAALEEVLAKDCPLVIDADALNLLAINNEKPA-REGPTVLTPHPGEFERLCGLAGI-LGDDRLEAARELAQKLNGTILL 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 416 KGAGTLIA-HADGVDLINSGNPGMASGGMGDLLTGVIAALIAQGMTLPAAARLAVWLHGEAGNRAAAEGGqRGLLATDLL 494
Cdd:pfam01256 159 KGNVTVIAaPGGEVWINSTGNSALAKGGSGDVLAGLIGGLLAQNEDPYDAAIAAAWLHGAASDLAAENHG-VYMLPTLLS 237


                  ....*
gi 2156602196 495 SHIRR 499
Cdd:pfam01256 238 KIIPR 242
YjeF_N pfam03853
YjeF-related protein N-terminus; YjeF-N domain is a novel version of the Rossmann fold with a ...
 36-198 2.15e-35

YjeF-related protein N-terminus; YjeF-N domain is a novel version of the Rossmann fold with a set of catalytic residues and structural features that are different from the conventional dehydrogenases. YjeF-N domain is fused to Ribokinases in bacteria (YjeF), where they may be phosphatases, and to divergent Sm and the FDF domain in eukaryotes (Dcp3p and FLJ21128), where they may be involved in decapping and catalyze hydrolytic RNA-processing reactions.


Pssm-ID: 427546 [Multi-domain]  Cd Length: 168  Bit Score: 129.65  E-value: 2.15e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196  36 GLTLMKRAGRAAFDRLRAHW-PEVNRIQVFCGGGNNGGDGYVIAGLAAQRKLPVVVYTAVSPEKLTGDALEAYRFAEREG 114
Cdd:pfam03853   1 SAVLMENAGRAAARVLKALLsPAGPKVLILCGPGNNGGDGLAAARHLANRGAKVTVLLLGPEEKLSEDARRQLDLFKKLG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 115 ---ATMVSDLAELSTADGNAVLVDALLGTGFSGELRAPVDTAVAHINASAAPVLAVDIPSGLNADSGA-AGEAVQADLTV 190
Cdd:pfam03853  81 gkiVTDNPDEDLEKLLSPVDLIIDALLGTGLSGPLRGEYAALIEWINQSGAPVLAVDIPSGLDADTGAvLGTAVRADHTV 160


                  ....*...
gi 2156602196 191 TFIGRKTG 198
Cdd:pfam03853 161 TFGAPKPG 168
yjeF_nterm TIGR00197
yjeF N-terminal region; The protein region corresponding to this model shows no clear homology ...
 14-216 2.20e-31

yjeF N-terminal region; The protein region corresponding to this model shows no clear homology to any protein of known function. This model is built on yeast protein YNL200C and the N-terminal regions of E. coli yjeF and its orthologs in various species. The C-terminal region of yjeF and its orthologs shows similarity to hydroxyethylthiazole kinase (thiM) and other enzymes involved in thiamine biosynthesis. Yeast YKL151C and B. subtilis yxkO match the yjeF C-terminal domain but lack this region. [Unknown function, General]


Pssm-ID: 272956 [Multi-domain]  Cd Length: 205  Bit Score: 120.21  E-value: 2.20e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196  14 KLYTAAAVQELDRLLISQQQIPGLTLMKRAGRAAFDRLRAHWPEVNRIQVFCGGGNNGGDGYVIAGLAAQRKLPVVVYTA 93
Cdd:TIGR00197   1 KVVVSPKDMAIDKENAEYLGLTLDLLMENAGKAVAQAVLQAYPLAGHVIIFCGPGNNGGDGFVVARHLKGFGVEVFLLKK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196  94 VSPEKLTGDALEAYRFAeREGATMVSDLAELSTADGNaVLVDALLGTGFSGELRAPVDTAVAHINASAAPVLAVDIPSGL 173
Cdd:TIGR00197  81 EKRIECTEQAEVNLKAL-KVGGISIDEGNLVKPEDCD-VIIDAILGTGFKGKLREPFKTIVESINELPAPIVSVDIPSGL 158

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 2156602196 174 NADSGA-AGEAVQADLTVTFIGRKTGLYLGRgPALTGEVIFDDL 216
Cdd:TIGR00197 159 DVDTGAiEGPAVNADLTITFHAIKPCLLSDR-ADVTGELKVGGI 201
PLN03050 PLN03050
pyridoxine (pyridoxamine) 5'-phosphate oxidase; Provisional
 109-198 5.63e-09

pyridoxine (pyridoxamine) 5'-phosphate oxidase; Provisional


Pssm-ID: 215551 [Multi-domain]  Cd Length: 246  Bit Score: 56.81  E-value: 5.63e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 109 FAEREGATMVSDLAELSTADgnaVLVDALLGTGFSGELRAPVDTAVAHIN---ASAAPVLAVDIPSGLNADSG-AAGEAV 184
Cdd:PLN03050  117 FVQAIGGTNDSSKPLETTYD---VIVDAIFGFSFHGAPRAPFDTLLAQMVqqqKSPPPIVSVDVPSGWDVDEGdVSGTGM 193

                          90
                  ....*....|....
gi 2156602196 185 QADLTVTFIGRKTG 198
Cdd:PLN03050  194 RPDVLVSLTAPKLS 207
THZ_kinase cd01170
4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the ...
 390-494 1.39e-08

4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine and 1-deoxy-D-xylulose-5-phosphate.


Pssm-ID: 238575 [Multi-domain]  Cd Length: 242  Bit Score: 55.62  E-value: 1.39e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 390 SKAEVVTDPVAAARAIQQKFSGVVILKGAGTLIAHADGVDLINSGNPGMAS-GGMGDLLTGVIAALIAQGMTLPAAARLA 468
Cdd:cd01170   133 SSSSDEEDALELAKALARKYGAVVVVTGEVDYITDGERVVVVKNGHPLLTKiTGTGCLLGAVIAAFLAVGDDPLEAAVSA 212

                          90       100
                  ....*....|....*....|....*.
gi 2156602196 469 VWLHGEAGNRAAAEGGQRGLLATDLL 494
Cdd:cd01170   213 VLVYGIAGELAAERAKGPGSFRVALL 238
PRK09355 PRK09355
hydroxyethylthiazole kinase; Validated
 392-482 1.69e-07

hydroxyethylthiazole kinase; Validated


Pssm-ID: 236477 [Multi-domain]  Cd Length: 263  Bit Score: 52.50  E-value: 1.69e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 392 AEVVTDPVAAARAIQQKFSGVVILKGAGTLIAHADGVDLINSGNPGMAS-GGMGDLLTGVIAALIAQGMTLPAAARLAVW 470
Cdd:PRK09355  139 TDGSADAVEIAKAAAKKYGTVVVVTGEVDYITDGERVVSVHNGHPLMTKvTGTGCLLSAVVAAFAAVEKDYLEAAAAACA 218

                          90
                  ....*....|..
gi 2156602196 471 LHGEAGNRAAAE 482
Cdd:PRK09355  219 VYGIAGELAAER 230
PLN03049 PLN03049
pyridoxine (pyridoxamine) 5'-phosphate oxidase; Provisional
 39-205 6.41e-06

pyridoxine (pyridoxamine) 5'-phosphate oxidase; Provisional


Pssm-ID: 215550 [Multi-domain]  Cd Length: 462  Bit Score: 48.69  E-value: 6.41e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196  39 LMKRAGRAAFDRLRAHWP--EVNRIQVFCGGGNNGGDgyviaGLAAQRKL------PVVVYTAVSPEKL-TG--DALEAY 107
Cdd:PLN03049   38 LMELAGLSVASAIAEVYSpsEYRRVLALCGPGNNGGD-----GLVAARHLhhfgykPSICYPKRTDKPLyNGlvTQLESL 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 108 RFAEREGATMVSDLAelSTADgnaVLVDALLGTGFSGELRAPVDTAVAHINASAA--PVLAVDIPSGLNADSG-AAGEAV 184
Cdd:PLN03049  113 SVPFLSVEDLPSDLS--SQFD---IVVDAMFGFSFHGAPRPPFDDLIQKLVRAAGppPIVSVDIPSGWHVEEGdVNGEGL 187

                         170       180
                  ....*....|....*....|.
gi 2156602196 185 QADLTVTFIGRKTGLYLGRGP 205
Cdd:PLN03049  188 KPDMLVSLTAPKLCAKMFKGP 208
ThiD COG0351
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase [Coenzyme transport and metabolism]; ...
 375-468 7.85e-06

Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase [Coenzyme transport and metabolism]; Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase is part of the Pathway/BioSystem: Thiamine biosynthesis


Pssm-ID: 440120 [Multi-domain]  Cd Length: 254  Bit Score: 47.34  E-value: 7.85e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 375 VLTPHIGEAARLLNTsKAEVVTDPVAAARAIQQKFSGVVILKGAgtliaHADG---VDL--------------INSGNpg 437
Cdd:COG0351   129 VVTPNLPEAEALLGI-EITTLDDMREAAKALLELGAKAVLVKGG-----HLPGdeaVDVlydgdgvrefsaprIDTGN-- 200

                          90       100       110
                  ....*....|....*....|....*....|.
gi 2156602196 438 maSGGMGDLLTGVIAALIAQGMTLPAAARLA 468
Cdd:COG0351   201 --THGTGCTLSSAIAALLAKGLDLEEAVREA 229
PLN02898 PLN02898
HMP-P kinase/thiamin-monophosphate pyrophosphorylase
 311-468 8.48e-06

HMP-P kinase/thiamin-monophosphate pyrophosphorylase


Pssm-ID: 215486 [Multi-domain]  Cd Length: 502  Bit Score: 48.23  E-value: 8.48e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 311 GQELEPLLELPSVIAVGPGLGQSPWSEQLLARAGRTEAALVLDADALNILAGGRVLAG-----VQRDDW-----VLTPHI 380
Cdd:PLN02898   67 AEQLKSVLSDMPVDVVKTGMLPSAEIVKVLCQALKEFPVKALVVDPVMVSTSGDVLAGpsilsALREELlplatIVTPNV 146

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 381 GEAARLLNTSKAEVVTDPVAAARAIQQKFSGVVILKGaGTLIAHADGVDLINSGNpGMAS-----------GGMGDLLTG 449
Cdd:PLN02898  147 KEASALLGGDPLETVADMRSAAKELHKLGPRYVLVKG-GHLPDSLDAVDVLYDGT-EFHElrssriktrntHGTGCTLAS 224

                         170
                  ....*....|....*....
gi 2156602196 450 VIAALIAQGMTLPAAARLA 468
Cdd:PLN02898  225 CIAAELAKGSDMLSAVKVA 243
PRK06427 PRK06427
bifunctional hydroxy-methylpyrimidine kinase/ hydroxy-phosphomethylpyrimidine kinase; Reviewed
 375-468 1.93e-05

bifunctional hydroxy-methylpyrimidine kinase/ hydroxy-phosphomethylpyrimidine kinase; Reviewed


Pssm-ID: 180561 [Multi-domain]  Cd Length: 266  Bit Score: 46.27  E-value: 1.93e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 375 VLTPHIGEAARLLNTSKAEVVTDPVAAARAIQQKFSGVVILKGaGTLIAHADGVDLINSGN----------PGMASGGMG 444
Cdd:PRK06427  136 LITPNLPEAEALTGLPIADTEDEMKAAARALHALGCKAVLIKG-GHLLDGEESVDWLFDGEgeerfsapriPTKNTHGTG 214

                          90       100
                  ....*....|....*....|....
gi 2156602196 445 DLLTGVIAALIAQGMTLPAAARLA 468
Cdd:PRK06427  215 CTLSAAIAAELAKGASLLDAVQTA 238
Phos_pyr_kin pfam08543
Phosphomethylpyrimidine kinase; This enzyme EC:2.7.4.7 is part of the Thiamine pyrophosphate ...
 375-468 8.31e-05

Phosphomethylpyrimidine kinase; This enzyme EC:2.7.4.7 is part of the Thiamine pyrophosphate (TPP) synthesis pathway, TPP is an essential cofactor for many enzymes.


Pssm-ID: 430062 [Multi-domain]  Cd Length: 246  Bit Score: 44.01  E-value: 8.31e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 375 VLTPHIGEAARLLNTsKAEVVTDPVAAARAIQQKFSGVVILKGAGTLIAHADGVDL--------------INSGNpgmaS 440
Cdd:pfam08543 122 LITPNLPEAEALTGR-KIKTLEDMKEAAKKLLALGAKAVLIKGGHLEGEEAVVTDVlydgggfytleaprIPTKN----T 196

                          90       100
                  ....*....|....*....|....*...
gi 2156602196 441 GGMGDLLTGVIAALIAQGMTLPAAARLA 468
Cdd:pfam08543 197 HGTGCTLSAAIAANLAKGLSLPEAVREA 224
PTZ00347 PTZ00347
phosphomethylpyrimidine kinase; Provisional
 375-469 3.12e-03

phosphomethylpyrimidine kinase; Provisional


Pssm-ID: 240375 [Multi-domain]  Cd Length: 504  Bit Score: 39.95  E-value: 3.12e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2156602196 375 VLTPHIGEAARLLNTSKAEVVTDPVAAARAIQQKFSGVVILKGAGTLIAHADGVDL----------------INSGNpgm 438
Cdd:PTZ00347  363 IITPNIPEAERILGRKEITGVYEARAAAQALAQYGSRYVLVKGGHDLIDPEACRDVlydrekdrfyeftanrIATIN--- 439

                          90       100       110
                  ....*....|....*....|....*....|.
gi 2156602196 439 aSGGMGDLLTGVIAALIAQGMTLPAAARLAV 469
Cdd:PTZ00347  440 -THGTGCTLASAISSFLARGYTVPDAVERAI 469
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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