|
Name |
Accession |
Description |
Interval |
E-value |
| murB |
PRK00046 |
UDP-N-acetylmuramate dehydrogenase; |
1-349 |
0e+00 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 234593 [Multi-domain] Cd Length: 334 Bit Score: 543.20 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 1 MLVENNVALQPLNSFGIAARAQRFARVRSEADLTGLMNGPDWAA-PVFVLGGGSNLVITGDIKALVLKVDIPGRRLVEET 79
Cdd:PRK00046 1 MQLQMNHSLKPLNTFGIDARARHLVEAESEEQLLEALADARAAGlPVLVLGGGSNVLFTEDFDGTVLLNRIKGIEVLSED 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 80 AKGWVVEAGAGENWHQFVAWTLVQGWPGLENLALIPGSVGASPVQNIGAYGVELQDRFHSLDAIDLQSGRAFTLDAAQCG 159
Cdd:PRK00046 81 DDAWYLHVGAGENWHDLVLWTLQQGMPGLENLALIPGTVGAAPIQNIGAYGVELKDVCDYVEALDLATGEFVRLSAAECR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 160 FGYRDSVFKHvptdarsfGLAGRALITRVRFLLPKPWKPVLGYLDLERKMAetgiHTPDAQQIFDWVVAIRRAKLPDPAV 239
Cdd:PRK00046 161 FGYRDSIFKH--------EYPDRYAITAVGFRLPKQWQPVLDYGDLARLDP----DTVTAQDVFDAVCAIRRSKLPDPKV 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 240 IGNAGSFFKNPTVTPEQCADIIARDPKVVHYPMPDGSIKLAAGWLIDACGWKGKSVGNAAVYEKQALVLVNRGGpshpCT 319
Cdd:PRK00046 229 LGNAGSFFKNPVVSAEQFEALLAQYPDIPHYPQADGSVKLAAGWLIDQCGLKGFQIGGAAVHEKQALVLVNYGN----AT 304
|
330 340 350
....*....|....*....|....*....|
gi 2116813794 320 GGEVMTLAKAIQTSVYERFGIRLEPEPVVV 349
Cdd:PRK00046 305 GADVLALARHIQQDVREKFGVELEPEPRFI 334
|
|
| MurB |
COG0812 |
UDP-N-acetylenolpyruvoylglucosamine reductase [Cell wall/membrane/envelope biogenesis]; ... |
7-349 |
2.97e-119 |
|
UDP-N-acetylenolpyruvoylglucosamine reductase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylenolpyruvoylglucosamine reductase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440574 [Multi-domain] Cd Length: 279 Bit Score: 345.46 E-value: 2.97e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 7 VALQPLNSFGIAARAQRFARVRSEADLTGLMNGPDWAA-PVFVLGGGSNLVITGD-IKALVLKV-DIPGRRLVEetakGW 83
Cdd:COG0812 1 EPLAPHTTFRIGGPADLLVEPASEEELAALLRAAREAGlPVLVLGGGSNLLVRDDgFDGLVIRLgRLKGIEVDD----GV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 84 VVEAGAGENWHQFVAWTLVQGWPGLENLALIPGSVGASPVQNIGAYGVELQDRFHSLDAIDlQSGRAFTLDAAQCGFGYR 163
Cdd:COG0812 77 LVTAGAGENWHDLVRFALEAGLSGLEFLAGIPGTVGGAPVMNAGAYGGEIKDVLESVEVLD-RTGEVRTLSAEECGFGYR 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 164 DSVFKHvptdarsfglaGRALITRVRFLLPKpwkpvlgyldlerkmaetgiHTPDA-QQIFDWVVAIRRAKlpDPAVIGN 242
Cdd:COG0812 156 DSIFKR-----------ERYIILSVTFRLKK--------------------GDPAEiAAVMDAVLAIRRSK--QPLELPS 202
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 243 AGSFFKNPtvtpeqcadiiardpkvvhypmPDGSiklaAGWLIDACGWKGKSVGNAAVYEKQALVLVNRGGpshpCTGGE 322
Cdd:COG0812 203 AGSFFKNP----------------------PGDS----AGWLIEQAGLKGYRIGGAQVSEKHANFLVNRGG----ATAAD 252
|
330 340
....*....|....*....|....*..
gi 2116813794 323 VMTLAKAIQTSVYERFGIRLEPEPVVV 349
Cdd:COG0812 253 VLALIEEVQARVKEKFGVELEPEVRII 279
|
|
| murB |
TIGR00179 |
UDP-N-acetylenolpyruvoylglucosamine reductase; This model describes MurB, ... |
9-345 |
1.66e-73 |
|
UDP-N-acetylenolpyruvoylglucosamine reductase; This model describes MurB, UDP-N-acetylenolpyruvoylglucosamine reductase, which is also called UDP-N-acetylmuramate dehydrogenase. It is part of the pathway for the biosynthesis of the UDP-N-acetylmuramoyl-pentapeptide that is a precursor of bacterial peptidoglycan. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 272945 [Multi-domain] Cd Length: 284 Bit Score: 229.26 E-value: 1.66e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 9 LQPLNSFGIAARAQRFARVRSEADLTGLMngpDWAA----PVFVLGGGSNLVITGDIKALVLKVDIPGRRLVEEtaKGWV 84
Cdd:TIGR00179 1 LAEFTTYKIGGNARHIVCPESIEQLVNVL---DNAKeedqPLLILGEGSNLLILDDGRGGVIINLGKGIDIEDD--EGEY 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 85 VEAGAGENWHQFVAWTLVQGWPGLENLALIPGSVGASPVQNIGAYGVELQDRFHSLDaIDLQSGRAFTLDAAQCGFGYRD 164
Cdd:TIGR00179 76 VHVGGGENWHKLVKYALKNGLSGLEFLAGIPGTVGGAVIMNAGAYGVEISEVLVYAT-ILLATGKTEWLTNEQLGFGYRT 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 165 SVFKHvptdarsfglagraliTRVRFLLPKPWKPVLGYldleRKMAETGIHTpdAQQIFDWVVAIRRAKLPDPavigNAG 244
Cdd:TIGR00179 155 SIFQH----------------KYVGLVLKAEFQLTLGF----GTRLDPETIT--AQQVFNKVCRMRTSHYPDP----NAG 208
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 245 SFFKNPTVTPeqcadiiardpkvvhypmpdgsiklaAGWLIDACGWKGKSVGNAAVYEKQALVLVNRGGpshpCTGGEVM 324
Cdd:TIGR00179 209 SFFKNPSPNH--------------------------AGRLIEECGLKGYQIGGAAVSKQHANFLVNIDN----AKSEDVL 258
|
330 340
....*....|....*....|.
gi 2116813794 325 TLAKAIQTSVYERFGIRLEPE 345
Cdd:TIGR00179 259 DLIEHVKAEVGEKYGILLEPE 279
|
|
| MurB_C |
pfam02873 |
UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Members of this family are ... |
222-349 |
8.96e-40 |
|
UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Members of this family are UDP-N-acetylenolpyruvoylglucosamine reductase enzymes EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan.
Pssm-ID: 460730 [Multi-domain] Cd Length: 99 Bit Score: 135.94 E-value: 8.96e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 222 IFDWVVAIRRAKL-PDPAVIGNAGSFFKNPtvtpeqcadiiardpkvvhypmpdgsIKLAAGWLIDACGWKGKSVGNAAV 300
Cdd:pfam02873 1 IRAAMLELRRRRLaKQPLDPPSAGSFFKNP--------------------------VGHSAGWLIEQAGLKGYRIGGAQV 54
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 2116813794 301 YEKQALVLVNRGGpshpCTGGEVMTLAKAIQTSVYERFGIRLEPEPVVV 349
Cdd:pfam02873 55 SEKHANFLVNTGG----ATAADVLALIEEVRERVKEKFGVELEPEVRII 99
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| murB |
PRK00046 |
UDP-N-acetylmuramate dehydrogenase; |
1-349 |
0e+00 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 234593 [Multi-domain] Cd Length: 334 Bit Score: 543.20 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 1 MLVENNVALQPLNSFGIAARAQRFARVRSEADLTGLMNGPDWAA-PVFVLGGGSNLVITGDIKALVLKVDIPGRRLVEET 79
Cdd:PRK00046 1 MQLQMNHSLKPLNTFGIDARARHLVEAESEEQLLEALADARAAGlPVLVLGGGSNVLFTEDFDGTVLLNRIKGIEVLSED 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 80 AKGWVVEAGAGENWHQFVAWTLVQGWPGLENLALIPGSVGASPVQNIGAYGVELQDRFHSLDAIDLQSGRAFTLDAAQCG 159
Cdd:PRK00046 81 DDAWYLHVGAGENWHDLVLWTLQQGMPGLENLALIPGTVGAAPIQNIGAYGVELKDVCDYVEALDLATGEFVRLSAAECR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 160 FGYRDSVFKHvptdarsfGLAGRALITRVRFLLPKPWKPVLGYLDLERKMAetgiHTPDAQQIFDWVVAIRRAKLPDPAV 239
Cdd:PRK00046 161 FGYRDSIFKH--------EYPDRYAITAVGFRLPKQWQPVLDYGDLARLDP----DTVTAQDVFDAVCAIRRSKLPDPKV 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 240 IGNAGSFFKNPTVTPEQCADIIARDPKVVHYPMPDGSIKLAAGWLIDACGWKGKSVGNAAVYEKQALVLVNRGGpshpCT 319
Cdd:PRK00046 229 LGNAGSFFKNPVVSAEQFEALLAQYPDIPHYPQADGSVKLAAGWLIDQCGLKGFQIGGAAVHEKQALVLVNYGN----AT 304
|
330 340 350
....*....|....*....|....*....|
gi 2116813794 320 GGEVMTLAKAIQTSVYERFGIRLEPEPVVV 349
Cdd:PRK00046 305 GADVLALARHIQQDVREKFGVELEPEPRFI 334
|
|
| MurB |
COG0812 |
UDP-N-acetylenolpyruvoylglucosamine reductase [Cell wall/membrane/envelope biogenesis]; ... |
7-349 |
2.97e-119 |
|
UDP-N-acetylenolpyruvoylglucosamine reductase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylenolpyruvoylglucosamine reductase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440574 [Multi-domain] Cd Length: 279 Bit Score: 345.46 E-value: 2.97e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 7 VALQPLNSFGIAARAQRFARVRSEADLTGLMNGPDWAA-PVFVLGGGSNLVITGD-IKALVLKV-DIPGRRLVEetakGW 83
Cdd:COG0812 1 EPLAPHTTFRIGGPADLLVEPASEEELAALLRAAREAGlPVLVLGGGSNLLVRDDgFDGLVIRLgRLKGIEVDD----GV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 84 VVEAGAGENWHQFVAWTLVQGWPGLENLALIPGSVGASPVQNIGAYGVELQDRFHSLDAIDlQSGRAFTLDAAQCGFGYR 163
Cdd:COG0812 77 LVTAGAGENWHDLVRFALEAGLSGLEFLAGIPGTVGGAPVMNAGAYGGEIKDVLESVEVLD-RTGEVRTLSAEECGFGYR 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 164 DSVFKHvptdarsfglaGRALITRVRFLLPKpwkpvlgyldlerkmaetgiHTPDA-QQIFDWVVAIRRAKlpDPAVIGN 242
Cdd:COG0812 156 DSIFKR-----------ERYIILSVTFRLKK--------------------GDPAEiAAVMDAVLAIRRSK--QPLELPS 202
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 243 AGSFFKNPtvtpeqcadiiardpkvvhypmPDGSiklaAGWLIDACGWKGKSVGNAAVYEKQALVLVNRGGpshpCTGGE 322
Cdd:COG0812 203 AGSFFKNP----------------------PGDS----AGWLIEQAGLKGYRIGGAQVSEKHANFLVNRGG----ATAAD 252
|
330 340
....*....|....*....|....*..
gi 2116813794 323 VMTLAKAIQTSVYERFGIRLEPEPVVV 349
Cdd:COG0812 253 VLALIEEVQARVKEKFGVELEPEVRII 279
|
|
| murB |
TIGR00179 |
UDP-N-acetylenolpyruvoylglucosamine reductase; This model describes MurB, ... |
9-345 |
1.66e-73 |
|
UDP-N-acetylenolpyruvoylglucosamine reductase; This model describes MurB, UDP-N-acetylenolpyruvoylglucosamine reductase, which is also called UDP-N-acetylmuramate dehydrogenase. It is part of the pathway for the biosynthesis of the UDP-N-acetylmuramoyl-pentapeptide that is a precursor of bacterial peptidoglycan. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 272945 [Multi-domain] Cd Length: 284 Bit Score: 229.26 E-value: 1.66e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 9 LQPLNSFGIAARAQRFARVRSEADLTGLMngpDWAA----PVFVLGGGSNLVITGDIKALVLKVDIPGRRLVEEtaKGWV 84
Cdd:TIGR00179 1 LAEFTTYKIGGNARHIVCPESIEQLVNVL---DNAKeedqPLLILGEGSNLLILDDGRGGVIINLGKGIDIEDD--EGEY 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 85 VEAGAGENWHQFVAWTLVQGWPGLENLALIPGSVGASPVQNIGAYGVELQDRFHSLDaIDLQSGRAFTLDAAQCGFGYRD 164
Cdd:TIGR00179 76 VHVGGGENWHKLVKYALKNGLSGLEFLAGIPGTVGGAVIMNAGAYGVEISEVLVYAT-ILLATGKTEWLTNEQLGFGYRT 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 165 SVFKHvptdarsfglagraliTRVRFLLPKPWKPVLGYldleRKMAETGIHTpdAQQIFDWVVAIRRAKLPDPavigNAG 244
Cdd:TIGR00179 155 SIFQH----------------KYVGLVLKAEFQLTLGF----GTRLDPETIT--AQQVFNKVCRMRTSHYPDP----NAG 208
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 245 SFFKNPTVTPeqcadiiardpkvvhypmpdgsiklaAGWLIDACGWKGKSVGNAAVYEKQALVLVNRGGpshpCTGGEVM 324
Cdd:TIGR00179 209 SFFKNPSPNH--------------------------AGRLIEECGLKGYQIGGAAVSKQHANFLVNIDN----AKSEDVL 258
|
330 340
....*....|....*....|.
gi 2116813794 325 TLAKAIQTSVYERFGIRLEPE 345
Cdd:TIGR00179 259 DLIEHVKAEVGEKYGILLEPE 279
|
|
| murB |
PRK13903 |
UDP-N-acetylmuramate dehydrogenase; |
6-349 |
2.77e-73 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 237552 [Multi-domain] Cd Length: 363 Bit Score: 231.00 E-value: 2.77e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 6 NVALQPLNSFGIAARAQRFARVRSEADLTGLMNGPDWAA-PVFVLGGGSNLVITGDIKAL-VLKVDIPGRRLVEETAkgw 83
Cdd:PRK13903 18 DVPLAPLTTLRVGGPARRLVTCTSTEELVAAVRELDAAGePLLVLGGGSNLVIADDGFDGtVVRVATRGVTVDCGGG--- 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 84 VVEAGAGENWHQFVAWTLVQGWPGLENLALIPGSVGASPVQNIGAYGVELQDRFHSLDAIDLQSGRAFTLDAAQCGFGYR 163
Cdd:PRK13903 95 LVRAEAGAVWDDVVARTVEAGLGGLECLSGIPGSAGATPVQNVGAYGQEVSDTITRVRLLDRRTGEVRWVPAADLGFGYR 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 164 DSVFKHvptdarsfglAGRALITRVRF-LLPKPWKPVLGYLDLERKM-AETGIHTPdAQQIFDWVVAIRRAK--LPDPA- 238
Cdd:PRK13903 175 TSVLKH----------SDRAVVLEVEFqLDPSGLSAPLRYGELARALgVEPGERVP-PAAVREAVLALRAGKgmVLDPAd 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 239 -VIGNAGSFFKNPTVTPEQCADIIAR-----DPKVVHYPMPDGSIKLAAGWLID----ACGWKGKSvGNAAVYEKQALVL 308
Cdd:PRK13903 244 hDTWSAGSFFTNPVVSPAVAERLAARvaerlGDPVPRYPAGDGGVKLSAAWLIEragfGKGYPGGG-APARLSTKHTLAL 322
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 2116813794 309 VNRGGpshpCTGGEVMTLAKAIQTSVYERFGIRLEPEPVVV 349
Cdd:PRK13903 323 TNRGG----ATTADLVALAREVRDGVRDAFGVTLVPEPVLV 359
|
|
| murB |
PRK13905 |
UDP-N-acetylmuramate dehydrogenase; |
6-345 |
1.71e-49 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 237553 [Multi-domain] Cd Length: 298 Bit Score: 167.60 E-value: 1.71e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 6 NVALQPLNSFGIAARAQRFARVRSEADLTGLMNG-PDWAAPVFVLGGGSNLVIT-GDIKALVLKVdipGRRLVEETAKGW 83
Cdd:PRK13905 16 NEPLARYTSFRVGGPADYLVEPADIEDLQEFLKLlKENNIPVTVLGNGSNLLVRdGGIRGVVIRL---GKGLNEIEVEGN 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 84 VVEAGAGENwHQFVAWTLV-QGWPGLENLALIPGSVGASPVQNIGAYGVELQDRFHSLDAIDlQSGRAFTLDAAQCGFGY 162
Cdd:PRK13905 93 RITAGAGAP-LIKLARFAAeAGLSGLEFAAGIPGTVGGAVFMNAGAYGGETADVLESVEVLD-RDGEIKTLSNEELGFGY 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 163 RDSVFKhvptdarsfglAGRALITRVRFLLPKpwkpvlG-YLDLERKMAEtgihtpdaqqifdwVVAIRRAKLP--DPav 239
Cdd:PRK13905 171 RHSALQ-----------EEGLIVLSATFQLEP------GdKEEIKARMDE--------------LLARREATQPleYP-- 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 240 igNAGSFFKNPTVtpeqcadiiardpkvvHYpmpdgsiklaAGWLIDACGWKGKSVGNAAVYEKQALVLVNRGGpshpCT 319
Cdd:PRK13905 218 --SAGSVFKNPPG----------------HF----------AGKLIEEAGLKGYRIGGAQVSEKHANFIINTGG----AT 265
|
330 340
....*....|....*....|....*.
gi 2116813794 320 GGEVMTLAKAIQTSVYERFGIRLEPE 345
Cdd:PRK13905 266 AADIEDLIEHVQKTVKEKFGVELEWE 291
|
|
| MurB_C |
pfam02873 |
UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Members of this family are ... |
222-349 |
8.96e-40 |
|
UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Members of this family are UDP-N-acetylenolpyruvoylglucosamine reductase enzymes EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan.
Pssm-ID: 460730 [Multi-domain] Cd Length: 99 Bit Score: 135.94 E-value: 8.96e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 222 IFDWVVAIRRAKL-PDPAVIGNAGSFFKNPtvtpeqcadiiardpkvvhypmpdgsIKLAAGWLIDACGWKGKSVGNAAV 300
Cdd:pfam02873 1 IRAAMLELRRRRLaKQPLDPPSAGSFFKNP--------------------------VGHSAGWLIEQAGLKGYRIGGAQV 54
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 2116813794 301 YEKQALVLVNRGGpshpCTGGEVMTLAKAIQTSVYERFGIRLEPEPVVV 349
Cdd:pfam02873 55 SEKHANFLVNTGG----ATAADVLALIEEVRERVKEKFGVELEPEVRII 99
|
|
| PRK14649 |
PRK14649 |
UDP-N-acetylmuramate dehydrogenase; |
9-349 |
7.52e-25 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 173112 [Multi-domain] Cd Length: 295 Bit Score: 102.23 E-value: 7.52e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 9 LQPLNSFGIAARAQRFARVRSEADLTGLMNgpdWAA----PVFVLGGGSNLVITGD-IKALVLKVDIPGRRLVE--ETAK 81
Cdd:PRK14649 9 LAPYTSWRIGGPARYFVEPTTPDEAIAAAA---WAEqrqlPLFWLGGGSNLLVRDEgFDGLVARYRGQRWELHEhgDTAE 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 82 GWVvEAGAGenwhqfVAWTL----VQGWPGLENLALIPGSVGASPVQNIGAYGVELQDRFHSLDAIdLQSGRAFTLDAAQ 157
Cdd:PRK14649 86 VWV-EAGAP------MAGTArrlaAQGWAGLEWAEGLPGTIGGAIYGNAGCYGGDTATVLIRAWLL-LNGSECVEWSVHD 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 158 CGFGYRDSVFKHVPTDarsfGLAGR-ALITRVRFLLPKPwKPVLgyldLERKMAETGihtpdaqqifdwvvAIRRAKLPD 236
Cdd:PRK14649 158 FAYGYRTSVLKQLRAD----GITWRpPLVLAARFRLHRD-DPTA----LAARMEAIA--------------AERKQKTPA 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 237 PAvigNAGSFFKNPTVTpeqcadiiardpkvvhypmpdgsiklAAGWLIDACGWKGKSVGNAAVYEKQALVLVNRGGpsh 316
Cdd:PRK14649 215 GS---SCGSVFKNPPGD--------------------------SAGRLIEAAGLKGTRIGDAEIATRHANYIINLGG--- 262
|
330 340 350
....*....|....*....|....*....|...
gi 2116813794 317 pCTGGEVMTLAKAIQTSVYERFGIRLEPEPVVV 349
Cdd:PRK14649 263 -ARAADILRLIDLARTRVLAQFGIELELEVRII 294
|
|
| PRK14651 |
PRK14651 |
UDP-N-acetylmuramate dehydrogenase; |
7-345 |
5.98e-18 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 237776 [Multi-domain] Cd Length: 273 Bit Score: 82.56 E-value: 5.98e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 7 VALQPLNSFGIAARAQRFArVRSEADLTGLMNgpdwaAPVFVLGGGSNLVITGD-IKALVLKVdipGRRLVEETAKGWVv 85
Cdd:PRK14651 7 VPLARYTTLGVGGPAELWT-VETHEQLAEATE-----APYRVLGGGSNLLVSDAgVPERVIRL---GGEFAEWDLDGWV- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 86 eaGAGENWHQFVAWTLVQGWPGLENLALIPGSVGASPVQNIGAYGVELQDRFHSLDAidLQSGRAFTLDAAQCGFGYRDS 165
Cdd:PRK14651 77 --GGGVPLPGLVRRAARLGLSGLEGLVGIPAQVGGAVKMNAGTRFGEMADALHTVEI--VHDGGFHQYSPDELGFGYRHS 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 166 vfkhvptdarsfGLAGRALITRVRF-LLPKPWKPVLgyldleRKMAEtgihtpdaqqifdwVVAIRRAKlPDPAvigNAG 244
Cdd:PRK14651 153 ------------GLPPGHVVTRVRLkLRPSTPEAVL------AKMAL--------------VDAARKGQ-PKKK---SAG 196
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 245 SFFKNPtvtpeqcadiiardPKVvhypmpdgsiklAAGWLIDACGWKGKSVGNAAVYEKQALVLVNRGGpshpCTGGEVM 324
Cdd:PRK14651 197 CAFKNP--------------PGD------------SAGRLIDEAGLKGTRVGDAMISPEHGNFIVNLGG----ATAADVH 246
|
330 340
....*....|....*....|.
gi 2116813794 325 TLAKAIQtsvyERFGIRLEPE 345
Cdd:PRK14651 247 ALLRRVR----ARVGLPLELE 263
|
|
| FAD_binding_4 |
pfam01565 |
FAD binding domain; This family consists of various enzymes that use FAD as a co-factor, most ... |
21-144 |
6.09e-17 |
|
FAD binding domain; This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. One of the enzymes Vanillyl-alcohol oxidase (VAO) has a solved structure, the alignment includes the FAD binding site, called the PP-loop, between residues 99-110. The FAD molecule is covalently bound in the known structure, however the residue that links to the FAD is not in the alignment. VAO catalyzes the oxidation of a wide variety of substrates, ranging form aromatic amines to 4-alkylphenols. Other members of this family include D-lactate dehydrogenase, this enzyme catalyzes the conversion of D-lactate to pyruvate using FAD as a co-factor; mitomycin radical oxidase, this enzyme oxidizes the reduced form of mitomycins and is involved in mitomycin resistance. This family includes MurB an UDP-N-acetylenolpyruvoylglucosamine reductase enzyme EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan.
Pssm-ID: 426326 [Multi-domain] Cd Length: 139 Bit Score: 76.47 E-value: 6.09e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 21 AQRFARVRSEADLTGLMNgpdWAA----PVFVLGGGSNLV-ITGDIKALVLKVDiPGRRLVEETAKGWVVEAGAGENWHQ 95
Cdd:pfam01565 1 PAAVVLPESEEEVAAIVR---LANenglPVLPRGGGSSLLgGAVQTGGIVLDLS-RLNGILEIDPEDGTATVEAGVTLGD 76
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 2116813794 96 FVAWTLVQG-WPGLENLALIPGSVGASPVQNIGAYGVELQ----DRFHSLDAID 144
Cdd:pfam01565 77 LVRALAAKGlLLGLDPGSGIPGTVGGAIATNAGGYGSEKYgltrDNVLGLEVVL 130
|
|
| PRK14653 |
PRK14653 |
UDP-N-acetylmuramate dehydrogenase; |
85-345 |
1.72e-16 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 237778 [Multi-domain] Cd Length: 297 Bit Score: 78.72 E-value: 1.72e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 85 VEAGAGENWHQFVAWTLVQGWPGLENLALIPGSVGASPVQNIGAYGVELQDRFHSLDAIDlqSGRAFTLDAAQCGFGYRD 164
Cdd:PRK14653 95 IICESGLSLKKLCLVAAKNGLSGFENAYGIPGSVGGAVYMNAGAYGWETAENIVEVVAYD--GKKIIRLGKNEIKFSYRN 172
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 165 SVFKHvptdarsfglAGRALITRVRFLLPKPWKpvlgYLDLERkMAETGIHTPDAQqifdwvvairraklpdPAVIGNAG 244
Cdd:PRK14653 173 SIFKE----------EKDLIILRVTFKLKKGNK----NEIYNL-MLETMKKRVEKQ----------------PLEFPSAG 221
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 245 SFFKNPTvtpeqcadiiardpkvvhypmPDgsikLAAGWLIDACGWKGKSVGNAAVYEKQALVLVNRGGpshpCTGGEVM 324
Cdd:PRK14653 222 SVFKRPR---------------------KD----FYVGSAIEKLGLKGFSIGGAQISEKHAGFIINYNN----AKAEDVL 272
|
250 260
....*....|....*....|.
gi 2116813794 325 TLAKAIQTSVYERFGIRLEPE 345
Cdd:PRK14653 273 KLIEYVKDKIYENYNVELETE 293
|
|
| PRK14652 |
PRK14652 |
UDP-N-acetylmuramate dehydrogenase; |
9-345 |
1.02e-14 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 237777 [Multi-domain] Cd Length: 302 Bit Score: 73.75 E-value: 1.02e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 9 LQPLNSFGIAARAQRFARVRSEADLTGLMNGP-DWAAPVFVLGGGSN-LVITGDIKALVLKvdIPGRrLVEETAKGWVVE 86
Cdd:PRK14652 24 LAPRTAVRVGGPADLLVRPADPDALSALLRAVrELGVPLSILGGGANtLVADAGVRGVVLR--LPQD-FPGESTDGGRLV 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 87 AGAGENWHQFVAWTLVQGWPGLENLALIPGSVGASPVQNIGAYGVELQDRFHSLDaIDLQSGRAFtLDAAQCGFGYRDSv 166
Cdd:PRK14652 101 LGAGAPISRLPARAHAHGLVGMEFLAGIPGTLGGAVAMNAGTKLGEMKDVVTAVE-LATADGAGF-VPAAALGYAYRTC- 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 167 fkhvptdarsfGLAGRALITRVRFLLPKPwkpvlgyldlerkmaetgiHTPDAQQIFDWVVAIRRAKlpDPAVIGNAGSF 246
Cdd:PRK14652 178 -----------RLPPGAVITRVEVRLRPG-------------------DVAASEALMRADRERRRRT--QPLDRPTFGST 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 247 FKNPtvtPEQcadiiardpkvvhypmpdgsiklAAGWLIDACGWKGKSVGNAAVYEKQALVLVNRGGpshpCTGGEVMTL 326
Cdd:PRK14652 226 FTNP---PGD-----------------------YAGRLVEAVGLKGHRVGGAIWSPVHANFVTNLGG----ATARDVLAL 275
|
330
....*....|....*....
gi 2116813794 327 AKAIQTSVYERFGIRLEPE 345
Cdd:PRK14652 276 VRLARARVKERFGIALETE 294
|
|
| murB |
PRK13904 |
UDP-N-acetylmuramate dehydrogenase; |
107-349 |
4.23e-12 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 184384 [Multi-domain] Cd Length: 257 Bit Score: 65.33 E-value: 4.23e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 107 GLENLALIPGSVGASPVQNIGAYGVELqdrFHSLDAIDLQSGRaftLDAAQCGFGYRDSVFKHVptdarsfglagralIT 186
Cdd:PRK13904 91 GFEFLGKLPGTLGGLVKMNAGLKEYEI---SNNLESICTNGGW---IEKEDIGFGYRSSGINGV--------------IL 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 187 RVRFLLPKPWKPVLgyLDLERKMaetgihtpdaqqifdwvvairRAKLPDPAvigNAGSFFKNPtvtpeqcadiiardpk 266
Cdd:PRK13904 151 EARFKKTHGFDEEL--LEAFKSM---------------------RKNQPKGP---SFGSCFKNP---------------- 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 267 VVHYpmpdgsiklaAGWLIDACGWKGKSVGNAAVYEKQALVLVNRGGPSHpCTGGEVMTLAKAiqtSVYERFGIRLEPEP 346
Cdd:PRK13904 189 KGDY----------AGRLIEAVGLKGYCKGGAGFSEEHANFLVNLGGATF-EDALDLIELAKK---RVLEEFGINLEEEV 254
|
...
gi 2116813794 347 VVV 349
Cdd:PRK13904 255 IIL 257
|
|
| PRK12436 |
PRK12436 |
UDP-N-acetylmuramate dehydrogenase; |
45-345 |
7.29e-12 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 171497 [Multi-domain] Cd Length: 305 Bit Score: 65.42 E-value: 7.29e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 45 PVFVLGGGSNLVIT-GDIKALVLKVdipgRRLVEETAKGWVVEAGAGENWHQFVAWTLVQGWPGLENLALIPGSVGASPV 123
Cdd:PRK12436 62 PVTFLGNGSNVIIKdGGIRGITVSL----IHITGVTVTGTTIVAQCGAAIIDVSRIALDHNLTGLEFACGIPGSVGGALY 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 124 QNIGAYGVELQdrFHSLDAIDL-QSGRAFTLDAAQCGFGYRDSVFKHvptdarsfglaGRALITRVRFLLPKPwkpvlGY 202
Cdd:PRK12436 138 MNAGAYGGEIS--FVLTEAVVMtGDGELRTLTKEAFEFGYRKSVFAN-----------NHYIILEARFELEEG-----VY 199
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 203 LDLERKMaetgihtpdaqqifDWVVAIRRAKLPdpavignagsfFKNPTvtpeqCADIIARDPKvvHYpmpdgsiklaAG 282
Cdd:PRK12436 200 EEIKAKM--------------DDLTFKRESKQP-----------LEYPS-----CGSVFKRPPN--NF----------AG 237
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2116813794 283 WLIDACGWKGKSVGNAAVYEKQALVLVNRGGPshpcTGGEVMTLAKAIQTSVYERFGIRLEPE 345
Cdd:PRK12436 238 KLIQESGLQGKRIGGVEVSLKHAGFMVNVDNG----TAQDYIDLIHFVQKTVEEKFGVKLERE 296
|
|
| PRK14648 |
PRK14648 |
UDP-N-acetylmuramate dehydrogenase; |
2-345 |
2.84e-11 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 173111 [Multi-domain] Cd Length: 354 Bit Score: 63.97 E-value: 2.84e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 2 LVENNVALQPLNSFGIAARAQRFARVRSEADLTGLMNGPDWA-APVFVLGGGSNLVITGD-IKALVLKVDiPGRRLVEET 79
Cdd:PRK14648 11 ITRRNVPLAERCSFRIGGAAQFWAEPRSCTQLRALIEEAQRArIPLSLIGGGSNVLIADEgVPGLMLSLR-RFRSLHTQT 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 80 AK--GWVVEAGAGENWHQFVAWTLVQGWPGLENLALIPGSVGASPVQNIGAYGVELQDRFHSLDAIDLQSGRA------- 150
Cdd:PRK14648 90 QRdgSVLVHAGAGLPVAALLAFCAHHALRGLETFAGLPGSVGGAAYMNARCYGRAIADCFHSARTLVLHPVRSrakelpe 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 151 -------------------FTLDAAQCGF------GYRDSVFKHvPTDARSFglAGRALITRVRFLLpKPWKPVLGYLDL 205
Cdd:PRK14648 170 vrknaqdkrgeclgldggpFTCSSFQTVFaragdwGYKRSPFQS-PHGVELH--AGRRLILSLCVRL-TPGNPAQIRKHM 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 206 ERKMAETgihtpdaqqifdwvvaIRRAKLPDPAvignAGSFFKNptvtpeqcadiiardpkvvhypmpDGSIKLAAGWLI 285
Cdd:PRK14648 246 QEKIADR----------------ISKGQFRFPS----AGSAFKN------------------------NPAFGKPSGILI 281
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 286 DACGWKGKSVGNAAVYEKQALVLVNRGGpshpCTGGEVMTLAKAIQTSVYERFGIRLEPE 345
Cdd:PRK14648 282 EEAGLRGTSCGAAQVAPWHGNLIINTGN----ATAHQVRTLLRVVRQRVFETHGVWLERE 337
|
|
| murB |
PRK13906 |
UDP-N-acetylmuramate dehydrogenase; |
45-345 |
6.55e-07 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 184386 [Multi-domain] Cd Length: 307 Bit Score: 50.20 E-value: 6.55e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 45 PVFVLGGGSNLVI-TGDIKALVLKVDIPGRRLVEETAkgwvVEAGAGENWHQFVAWTLVQGWPGLENLALIPGSVGASPV 123
Cdd:PRK13906 62 PVTYLGNGSNIIIrEGGIRGIVISLLSLDHIEVSDDA----IIAGSGAAIIDVSRVARDYALTGLEFACGIPGSIGGAVY 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 124 QNIGAYGVELQDRFHSLDAIDlQSGRAFTLDAAQCGFGYRDSVF--KHVPTDARSFGLAGralitrvrfllpkpwkpvlG 201
Cdd:PRK13906 138 MNAGAYGGEVKDCIDYALCVN-EQGSLIKLTTKELELDYRNSIIqkEHLVVLEAAFTLAP-------------------G 197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2116813794 202 YLDlerkmaetgihtpDAQQIFDWVVAIRRAKLPdpavignagsfFKNPTvtpeqCADIIARDPKvvHYpmpdgsiklaA 281
Cdd:PRK13906 198 KMT-------------EIQAKMDDLTERRESKQP-----------LEYPS-----CGSVFQRPPG--HF----------A 236
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2116813794 282 GWLIDACGWKGKSVGNAAVYEKQA--LVLVNRGgpshpcTGGEVMTLAKAIQTSVYERFGIRLEPE 345
Cdd:PRK13906 237 GKLIQDSNLQGHRIGGVEVSTKHAgfMVNVDNG------TATDYENLIHYVQKTVKEKFGIELNRE 296
|
|
| |
