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Conserved domains on  [gi|1633525015|gb|TKH21154|]
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DUF11 domain-containing protein, partial [Bacillus cereus]

Protein Classification

DUF11 domain-containing protein( domain architecture ID 12855254)

DUF11 domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
B_ant_repeat TIGR01451
conserved repeat domain; This model represents the conserved region of about 53 amino acids ...
4-55 2.27e-10

conserved repeat domain; This model represents the conserved region of about 53 amino acids shared between regions, usually repeated, of proteins from a small number of phylogenetically distant prokaryotes. Examples include a 132-residue region found repeated in three of the five longest proteins of Bacillus anthracis, a 131-residue repeat in a cell wall-anchored protein of Enterococcus faecalis, and a 120-residue repeat in Methanobacterium thermoautotrophicum. A similar region is found in some Chlamydial outer membrane proteins.


:

Pssm-ID: 273634 [Multi-domain]  Cd Length: 53  Bit Score: 53.77  E-value: 2.27e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1633525015   4 KSVDKTFATIGDTISYTITLNNPGNVTSQNIIFTDILPDGTTFISGTLTNDS 55
Cdd:TIGR01451   1 KTVDKTVATIGDTITYTITVTNNGNVPATNVVVTDILPAGTTFVSNSVTVNG 52
DUF11 super family cl47654
Domain of unknown function DUF11; A domain of unknown function found in multiple copies in ...
4-108 5.21e-08

Domain of unknown function DUF11; A domain of unknown function found in multiple copies in several archaebacterial proteins. Conserved N-terminal lysine and C-terminal asparagine with central asp/glu suggests that many of these domain may contain an isopeptide bond. In Methanothermobacter sp. CaT2, a DUF11-containing repeat hypothetical protein encoded by MTCT_1020 plays a key role as a membrane-bound adhesion protein in the aggregation of CaT2. DUF11-containing repeat domains are not involved in aggregation, but may be important for stabilizing the surface cell wall structures of CaT2.


The actual alignment was detected with superfamily member pfam01345:

Pssm-ID: 460168 [Multi-domain]  Cd Length: 114  Bit Score: 49.14  E-value: 5.21e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1633525015   4 KSVDKTFATIGDTISYTITLNNPGNVTSQNIIFTDILPDGTTFISGTltndsGTQQIGNPASGI-QIGNINPNGTAVISL 82
Cdd:pfam01345   6 KTVDNTTPNVGDTVTFTITVTNNGPSDATGVVVTDTLPAGLTFVSAT-----ASQGTYDSATGIwTIGSLAVGASATLTI 80
                          90       100
                  ....*....|....*....|....*.
gi 1633525015  83 NVLVTNIPSINPISNFSSIQFEHVID 108
Cdd:pfam01345  81 TATVNTAGTITNTATVTSSTFDPNLS 106
B_ant_repeat super family cl47127
conserved repeat domain; This model represents the conserved region of about 53 amino acids ...
136-188 1.01e-03

conserved repeat domain; This model represents the conserved region of about 53 amino acids shared between regions, usually repeated, of proteins from a small number of phylogenetically distant prokaryotes. Examples include a 132-residue region found repeated in three of the five longest proteins of Bacillus anthracis, a 131-residue repeat in a cell wall-anchored protein of Enterococcus faecalis, and a 120-residue repeat in Methanobacterium thermoautotrophicum. A similar region is found in some Chlamydial outer membrane proteins.


The actual alignment was detected with superfamily member TIGR01451:

Pssm-ID: 273634 [Multi-domain]  Cd Length: 53  Bit Score: 36.05  E-value: 1.01e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1633525015 136 KSVDKSIISVGDTLTYTTTITNTGNTPATNITFTSAIPASTTFIPDSVTINGI 188
Cdd:TIGR01451   1 KTVDKTVATIGDTITYTITVTNNGNVPATNVVVTDILPAGTTFVSNSVTVNGV 53
 
Name Accession Description Interval E-value
B_ant_repeat TIGR01451
conserved repeat domain; This model represents the conserved region of about 53 amino acids ...
4-55 2.27e-10

conserved repeat domain; This model represents the conserved region of about 53 amino acids shared between regions, usually repeated, of proteins from a small number of phylogenetically distant prokaryotes. Examples include a 132-residue region found repeated in three of the five longest proteins of Bacillus anthracis, a 131-residue repeat in a cell wall-anchored protein of Enterococcus faecalis, and a 120-residue repeat in Methanobacterium thermoautotrophicum. A similar region is found in some Chlamydial outer membrane proteins.


Pssm-ID: 273634 [Multi-domain]  Cd Length: 53  Bit Score: 53.77  E-value: 2.27e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1633525015   4 KSVDKTFATIGDTISYTITLNNPGNVTSQNIIFTDILPDGTTFISGTLTNDS 55
Cdd:TIGR01451   1 KTVDKTVATIGDTITYTITVTNNGNVPATNVVVTDILPAGTTFVSNSVTVNG 52
DUF11 pfam01345
Domain of unknown function DUF11; A domain of unknown function found in multiple copies in ...
4-108 5.21e-08

Domain of unknown function DUF11; A domain of unknown function found in multiple copies in several archaebacterial proteins. Conserved N-terminal lysine and C-terminal asparagine with central asp/glu suggests that many of these domain may contain an isopeptide bond. In Methanothermobacter sp. CaT2, a DUF11-containing repeat hypothetical protein encoded by MTCT_1020 plays a key role as a membrane-bound adhesion protein in the aggregation of CaT2. DUF11-containing repeat domains are not involved in aggregation, but may be important for stabilizing the surface cell wall structures of CaT2.


Pssm-ID: 460168 [Multi-domain]  Cd Length: 114  Bit Score: 49.14  E-value: 5.21e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1633525015   4 KSVDKTFATIGDTISYTITLNNPGNVTSQNIIFTDILPDGTTFISGTltndsGTQQIGNPASGI-QIGNINPNGTAVISL 82
Cdd:pfam01345   6 KTVDNTTPNVGDTVTFTITVTNNGPSDATGVVVTDTLPAGLTFVSAT-----ASQGTYDSATGIwTIGSLAVGASATLTI 80
                          90       100
                  ....*....|....*....|....*.
gi 1633525015  83 NVLVTNIPSINPISNFSSIQFEHVID 108
Cdd:pfam01345  81 TATVNTAGTITNTATVTSSTFDPNLS 106
B_ant_repeat TIGR01451
conserved repeat domain; This model represents the conserved region of about 53 amino acids ...
136-188 1.01e-03

conserved repeat domain; This model represents the conserved region of about 53 amino acids shared between regions, usually repeated, of proteins from a small number of phylogenetically distant prokaryotes. Examples include a 132-residue region found repeated in three of the five longest proteins of Bacillus anthracis, a 131-residue repeat in a cell wall-anchored protein of Enterococcus faecalis, and a 120-residue repeat in Methanobacterium thermoautotrophicum. A similar region is found in some Chlamydial outer membrane proteins.


Pssm-ID: 273634 [Multi-domain]  Cd Length: 53  Bit Score: 36.05  E-value: 1.01e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1633525015 136 KSVDKSIISVGDTLTYTTTITNTGNTPATNITFTSAIPASTTFIPDSVTINGI 188
Cdd:TIGR01451   1 KTVDKTVATIGDTITYTITVTNNGNVPATNVVVTDILPAGTTFVSNSVTVNGV 53
 
Name Accession Description Interval E-value
B_ant_repeat TIGR01451
conserved repeat domain; This model represents the conserved region of about 53 amino acids ...
4-55 2.27e-10

conserved repeat domain; This model represents the conserved region of about 53 amino acids shared between regions, usually repeated, of proteins from a small number of phylogenetically distant prokaryotes. Examples include a 132-residue region found repeated in three of the five longest proteins of Bacillus anthracis, a 131-residue repeat in a cell wall-anchored protein of Enterococcus faecalis, and a 120-residue repeat in Methanobacterium thermoautotrophicum. A similar region is found in some Chlamydial outer membrane proteins.


Pssm-ID: 273634 [Multi-domain]  Cd Length: 53  Bit Score: 53.77  E-value: 2.27e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1633525015   4 KSVDKTFATIGDTISYTITLNNPGNVTSQNIIFTDILPDGTTFISGTLTNDS 55
Cdd:TIGR01451   1 KTVDKTVATIGDTITYTITVTNNGNVPATNVVVTDILPAGTTFVSNSVTVNG 52
DUF11 pfam01345
Domain of unknown function DUF11; A domain of unknown function found in multiple copies in ...
4-108 5.21e-08

Domain of unknown function DUF11; A domain of unknown function found in multiple copies in several archaebacterial proteins. Conserved N-terminal lysine and C-terminal asparagine with central asp/glu suggests that many of these domain may contain an isopeptide bond. In Methanothermobacter sp. CaT2, a DUF11-containing repeat hypothetical protein encoded by MTCT_1020 plays a key role as a membrane-bound adhesion protein in the aggregation of CaT2. DUF11-containing repeat domains are not involved in aggregation, but may be important for stabilizing the surface cell wall structures of CaT2.


Pssm-ID: 460168 [Multi-domain]  Cd Length: 114  Bit Score: 49.14  E-value: 5.21e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1633525015   4 KSVDKTFATIGDTISYTITLNNPGNVTSQNIIFTDILPDGTTFISGTltndsGTQQIGNPASGI-QIGNINPNGTAVISL 82
Cdd:pfam01345   6 KTVDNTTPNVGDTVTFTITVTNNGPSDATGVVVTDTLPAGLTFVSAT-----ASQGTYDSATGIwTIGSLAVGASATLTI 80
                          90       100
                  ....*....|....*....|....*.
gi 1633525015  83 NVLVTNIPSINPISNFSSIQFEHVID 108
Cdd:pfam01345  81 TATVNTAGTITNTATVTSSTFDPNLS 106
B_ant_repeat TIGR01451
conserved repeat domain; This model represents the conserved region of about 53 amino acids ...
136-188 1.01e-03

conserved repeat domain; This model represents the conserved region of about 53 amino acids shared between regions, usually repeated, of proteins from a small number of phylogenetically distant prokaryotes. Examples include a 132-residue region found repeated in three of the five longest proteins of Bacillus anthracis, a 131-residue repeat in a cell wall-anchored protein of Enterococcus faecalis, and a 120-residue repeat in Methanobacterium thermoautotrophicum. A similar region is found in some Chlamydial outer membrane proteins.


Pssm-ID: 273634 [Multi-domain]  Cd Length: 53  Bit Score: 36.05  E-value: 1.01e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1633525015 136 KSVDKSIISVGDTLTYTTTITNTGNTPATNITFTSAIPASTTFIPDSVTINGI 188
Cdd:TIGR01451   1 KTVDKTVATIGDTITYTITVTNNGNVPATNVVVTDILPAGTTFVSNSVTVNGV 53
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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