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Conserved domains on  [gi|1460644627|emb|SXF43396|]
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FAD-dependent pyridine nucleotide-disulfide oxidoreductase [Klebsiella variicola]

Protein Classification

NAD(P)/FAD-dependent oxidoreductase( domain architecture ID 11441299)

NAD(P)/FAD-dependent oxidoreductase catalyzes the transfer of electrons from one molecule, the electron donor or reductant, to another molecule, the electron acceptor or oxidant; similar to sulfide:quinone oxidoreductase which catalyzes the oxidation of hydrogen sulfide using quinone as the electron acceptor

EC:  1.6.-.-
Gene Ontology:  GO:0003954|GO:0006116
PubMed:  15590775|28181562

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
Ndh COG1252
NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];
18-416 3.32e-155

NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];


:

Pssm-ID: 440864 [Multi-domain]  Cd Length: 386  Bit Score: 444.19  E-value: 3.32e-155
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627  18 LELATQLGKKLGrhKKAKITLVDRNHSHLWKPLLHEVATGSLDEGVDALSYLAHARNHGFQFQLGSVVDINREGKTITLg 97
Cdd:COG1252    14 LEAARRLRKKLG--GDAEVTLIDPNPYHLFQPLLPEVAAGTLSPDDIAIPLRELLRRAGVRFIQGEVTGIDPEARTVTL- 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627  98 elrnEKGellvaeRKLPYDTLVMALGSTSNDFNTPGVKENCIFLDNPHQARRFHQEMLNLFLKYSANlganGKVNIAIVG 177
Cdd:COG1252    91 ----ADG------RTLSYDYLVIATGSVTNFFGIPGLAEHALPLKTLEDALALRERLLAAFERAERR----RLLTIVVVG 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 178 GGATGVELSAELHNAVKQLHSYgyKGLTNEALNVTLVEAGERILPALPPRISGAAHNELTKLGVRVLTQTMVTSADAGGL 257
Cdd:COG1252   157 GGPTGVELAGELAELLRKLLRY--PGIDPDKVRITLVEAGPRILPGLGEKLSEAAEKELEKRGVEVHTGTRVTEVDADGV 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 258 HTKDGEYIEADLMVWAAGIKAPDFMKEIGgLETNRINQLVVEPTLQTTRDADIFAIGDCASCARPEGGFVPPRAQAAHQM 337
Cdd:COG1252   235 TLEDGEEIPADTVIWAAGVKAPPLLADLG-LPTDRRGRVLVDPTLQVPGHPNVFAIGDCAAVPDPDGKPVPKTAQAAVQQ 313

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1460644627 338 ATCALNNILAQMKGKPLKAYTYKDHGSLVSLSNYSTVGSLMGnlmrgsMMVEGRIARFVYISLYRMHQIALHGYFKTGL 416
Cdd:COG1252   314 AKVLAKNIAALLRGKPLKPFRYRDKGCLASLGRGAAVADVGG------LKLSGFLAWLLKRAIHLYFLPGFRGRLRVLL 386
 
Name Accession Description Interval E-value
Ndh COG1252
NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];
18-416 3.32e-155

NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];


Pssm-ID: 440864 [Multi-domain]  Cd Length: 386  Bit Score: 444.19  E-value: 3.32e-155
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627  18 LELATQLGKKLGrhKKAKITLVDRNHSHLWKPLLHEVATGSLDEGVDALSYLAHARNHGFQFQLGSVVDINREGKTITLg 97
Cdd:COG1252    14 LEAARRLRKKLG--GDAEVTLIDPNPYHLFQPLLPEVAAGTLSPDDIAIPLRELLRRAGVRFIQGEVTGIDPEARTVTL- 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627  98 elrnEKGellvaeRKLPYDTLVMALGSTSNDFNTPGVKENCIFLDNPHQARRFHQEMLNLFLKYSANlganGKVNIAIVG 177
Cdd:COG1252    91 ----ADG------RTLSYDYLVIATGSVTNFFGIPGLAEHALPLKTLEDALALRERLLAAFERAERR----RLLTIVVVG 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 178 GGATGVELSAELHNAVKQLHSYgyKGLTNEALNVTLVEAGERILPALPPRISGAAHNELTKLGVRVLTQTMVTSADAGGL 257
Cdd:COG1252   157 GGPTGVELAGELAELLRKLLRY--PGIDPDKVRITLVEAGPRILPGLGEKLSEAAEKELEKRGVEVHTGTRVTEVDADGV 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 258 HTKDGEYIEADLMVWAAGIKAPDFMKEIGgLETNRINQLVVEPTLQTTRDADIFAIGDCASCARPEGGFVPPRAQAAHQM 337
Cdd:COG1252   235 TLEDGEEIPADTVIWAAGVKAPPLLADLG-LPTDRRGRVLVDPTLQVPGHPNVFAIGDCAAVPDPDGKPVPKTAQAAVQQ 313

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1460644627 338 ATCALNNILAQMKGKPLKAYTYKDHGSLVSLSNYSTVGSLMGnlmrgsMMVEGRIARFVYISLYRMHQIALHGYFKTGL 416
Cdd:COG1252   314 AKVLAKNIAALLRGKPLKPFRYRDKGCLASLGRGAAVADVGG------LKLSGFLAWLLKRAIHLYFLPGFRGRLRVLL 386
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 30-338 1.30e-56

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 188.68  E-value: 1.30e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627  30 RHKKAKITLV-DRNHSHLWKPLLHEVATGSLDEGVDAL---SYLAHARNHGFQFQLG-------SVVDINREGKTITLGE 98
Cdd:pfam07992  20 AQLGGKVTLIeDEGTCPYGGCVLSKALLGAAEAPEIASlwaDLYKRKEEVVKKLNNGievllgtEVVSIDPGAKKVVLEE 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627  99 LRNEKGEllvaerKLPYDTLVMALGSTSNDFNTPGVKENCIFL-DNPHQARRFHQEMLNLflkysanlgangkvNIAIVG 177
Cdd:pfam07992 100 LVDGDGE------TITYDRLVIATGARPRLPPIPGVELNVGFLvRTLDSAEALRLKLLPK--------------RVVVVG 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 178 GGATGVELSAELHNAVKQlhsygykgltnealnVTLVEAGERILPALPPRISGAAHNELTKLGVRVLTQTMVTSADAGG- 256
Cdd:pfam07992 160 GGYIGVELAAALAKLGKE---------------VTLIEALDRLLRAFDEEISAALEKALEKNGVEVRLGTSVKEIIGDGd 224

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 257 ---LHTKDGEYIEADLMVWAAGIKAPDFMKEIGGLETNRINQLVVEPTLQTTRDaDIFAIGDCascarpeGGFVPPRAQA 333
Cdd:pfam07992 225 gveVILKDGTEIDADLVVVAIGRRPNTELLEAAGLELDERGGIVVDEYLRTSVP-GIYAAGDC-------RVGGPELAQN 296


                  ....*
gi 1460644627 334 AHQMA 338
Cdd:pfam07992 297 AVAQG 301
PTZ00318 PTZ00318
NADH dehydrogenase-like protein; Provisional
 31-401 3.64e-47

NADH dehydrogenase-like protein; Provisional


Pssm-ID: 185553 [Multi-domain]  Cd Length: 424  Bit Score: 167.25  E-value: 3.64e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627  31 HKKAKITLVD-RNHsHLWKPLLHEVATGSLdEGVDALSYLAHARNH-GFQFQLGSVVDINREGKTITLGELRNEKGELlV 108
Cdd:PTZ00318   31 PKKYNITVISpRNH-MLFTPLLPQTTTGTL-EFRSICEPVRPALAKlPNRYLRAVVYDVDFEEKRVKCGVVSKSNNAN-V 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 109 AERKLPYDTLVMALGSTSNDFNTPGVKENCIFLDNPHQARRFHQEMLNLFLKysANLG------ANGKVNIAIVGGGATG 182
Cdd:PTZ00318  108 NTFSVPYDKLVVAHGARPNTFNIPGVEERAFFLKEVNHARGIRKRIVQCIER--ASLPttsveeRKRLLHFVVVGGGPTG 185

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 183 VELSAELHNAVKQLHSYGYKGLTNEAlNVTLVEAGERILPALPPRISGAAHNELTKLGVRVLTQTMVTSADAGGLHTKDG 262
Cdd:PTZ00318  186 VEFAAELADFFRDDVRNLNPELVEEC-KVTVLEAGSEVLGSFDQALRKYGQRRLRRLGVDIRTKTAVKEVLDKEVVLKDG 264

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 263 EYIEADLMVWAAGIKAPDFMKEIGGLETNRiNQLVVEPTLQTTRDADIFAIGDCASCarpEGGFVPPRAQAAHQMATCAL 342
Cdd:PTZ00318  265 EVIPTGLVVWSTGVGPGPLTKQLKVDKTSR-GRISVDDHLRVKPIPNVFALGDCAAN---EERPLPTLAQVASQQGVYLA 340

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 343 NNILAQMKGKPL-KAYTYKDHGSLVSLSNYSTVGSLmgnlmrGSMMVEGRIARFVYISLY 401
Cdd:PTZ00318  341 KEFNNELKGKPMsKPFVYRSLGSLAYLGNYSAIVQL------GAFDLSGFKALLFWRSAY 394
Nterm_to_SelD TIGR03169
pyridine nucleotide-disulfide oxidoreductase family protein; Members of this protein family ...
 72-391 2.77e-40

pyridine nucleotide-disulfide oxidoreductase family protein; Members of this protein family include N-terminal sequence regions of (probable) bifunctional proteins whose C-terminal sequences are SelD, or selenide,water dikinase, the selenium donor protein necessary for selenium incorporation into protein (as selenocysteine), tRNA (as 2-selenouridine), or both. However, some members of this family occur in species that do not show selenium incorporation, and the function of this protein family is unknown.


Pssm-ID: 274465  Cd Length: 364  Bit Score: 147.35  E-value: 2.77e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627  72 ARNHGFQFQLGSVVDINREGKTITLgelrnEKGellvaeRKLPYDTLVMALGSTSNDFNTPGVKENCI-------FLDNP 144
Cdd:TIGR03169  64 ARFAGARLILDRAIGLDLAAKQVIC-----AGR------PPIAYDVLSIDIGSTPALPDVPGFAEHAIpakplgqFAQRW 132

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 145 HQarrfhqemlnlflkYSANLGANGKVNIAIVGGGATGVELSAELHNAVKQLHSygykgltneALNVTLVEAGERILPAL 224
Cdd:TIGR03169 133 QR--------------FLERAKPQQPPRIAVIGGGAAGVELALAMAHRLRQLGR---------NAEVTLIDRGNVLLPGH 189

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 225 PPRISGAAHNELTKLGVRVLTQTMVTSADAGGLHTKDGEYIEADLMVWAAGIKAPDFMKEIGgLETNRINQLVVEPTLQT 304
Cdd:TIGR03169 190 NARVRRRLERALQERGVTLHLGATVAEVTADAVRLEDGQTLPADFTFWATGARPPGWLAESG-LALDEDGFIRVGPTLQS 268

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 305 TRDADIFAIGDCAScarpeggFVP-PRAQA---AHQMATCALNNILAQMKGKPLKAYT-YKDHGSLVSLSNYSTVGSlmg 379
Cdd:TIGR03169 269 LSHPDIFAAGDCAH-------LVHaPRPKAgvfAVRQAPVLAENLRAALTGGPLRPYRpQSDYLKLISTGDKSAVAS--- 338

                         330
                  ....*....|..
gi 1460644627 380 nlmRGSMMVEGR 391
Cdd:TIGR03169 339 ---RGGLAFSGA 347
 
Name Accession Description Interval E-value
Ndh COG1252
NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];
18-416 3.32e-155

NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];


Pssm-ID: 440864 [Multi-domain]  Cd Length: 386  Bit Score: 444.19  E-value: 3.32e-155
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627  18 LELATQLGKKLGrhKKAKITLVDRNHSHLWKPLLHEVATGSLDEGVDALSYLAHARNHGFQFQLGSVVDINREGKTITLg 97
Cdd:COG1252    14 LEAARRLRKKLG--GDAEVTLIDPNPYHLFQPLLPEVAAGTLSPDDIAIPLRELLRRAGVRFIQGEVTGIDPEARTVTL- 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627  98 elrnEKGellvaeRKLPYDTLVMALGSTSNDFNTPGVKENCIFLDNPHQARRFHQEMLNLFLKYSANlganGKVNIAIVG 177
Cdd:COG1252    91 ----ADG------RTLSYDYLVIATGSVTNFFGIPGLAEHALPLKTLEDALALRERLLAAFERAERR----RLLTIVVVG 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 178 GGATGVELSAELHNAVKQLHSYgyKGLTNEALNVTLVEAGERILPALPPRISGAAHNELTKLGVRVLTQTMVTSADAGGL 257
Cdd:COG1252   157 GGPTGVELAGELAELLRKLLRY--PGIDPDKVRITLVEAGPRILPGLGEKLSEAAEKELEKRGVEVHTGTRVTEVDADGV 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 258 HTKDGEYIEADLMVWAAGIKAPDFMKEIGgLETNRINQLVVEPTLQTTRDADIFAIGDCASCARPEGGFVPPRAQAAHQM 337
Cdd:COG1252   235 TLEDGEEIPADTVIWAAGVKAPPLLADLG-LPTDRRGRVLVDPTLQVPGHPNVFAIGDCAAVPDPDGKPVPKTAQAAVQQ 313

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1460644627 338 ATCALNNILAQMKGKPLKAYTYKDHGSLVSLSNYSTVGSLMGnlmrgsMMVEGRIARFVYISLYRMHQIALHGYFKTGL 416
Cdd:COG1252   314 AKVLAKNIAALLRGKPLKPFRYRDKGCLASLGRGAAVADVGG------LKLSGFLAWLLKRAIHLYFLPGFRGRLRVLL 386
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 30-338 1.30e-56

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 188.68  E-value: 1.30e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627  30 RHKKAKITLV-DRNHSHLWKPLLHEVATGSLDEGVDAL---SYLAHARNHGFQFQLG-------SVVDINREGKTITLGE 98
Cdd:pfam07992  20 AQLGGKVTLIeDEGTCPYGGCVLSKALLGAAEAPEIASlwaDLYKRKEEVVKKLNNGievllgtEVVSIDPGAKKVVLEE 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627  99 LRNEKGEllvaerKLPYDTLVMALGSTSNDFNTPGVKENCIFL-DNPHQARRFHQEMLNLflkysanlgangkvNIAIVG 177
Cdd:pfam07992 100 LVDGDGE------TITYDRLVIATGARPRLPPIPGVELNVGFLvRTLDSAEALRLKLLPK--------------RVVVVG 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 178 GGATGVELSAELHNAVKQlhsygykgltnealnVTLVEAGERILPALPPRISGAAHNELTKLGVRVLTQTMVTSADAGG- 256
Cdd:pfam07992 160 GGYIGVELAAALAKLGKE---------------VTLIEALDRLLRAFDEEISAALEKALEKNGVEVRLGTSVKEIIGDGd 224

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 257 ---LHTKDGEYIEADLMVWAAGIKAPDFMKEIGGLETNRINQLVVEPTLQTTRDaDIFAIGDCascarpeGGFVPPRAQA 333
Cdd:pfam07992 225 gveVILKDGTEIDADLVVVAIGRRPNTELLEAAGLELDERGGIVVDEYLRTSVP-GIYAAGDC-------RVGGPELAQN 296


                  ....*
gi 1460644627 334 AHQMA 338
Cdd:pfam07992 297 AVAQG 301
PTZ00318 PTZ00318
NADH dehydrogenase-like protein; Provisional
 31-401 3.64e-47

NADH dehydrogenase-like protein; Provisional


Pssm-ID: 185553 [Multi-domain]  Cd Length: 424  Bit Score: 167.25  E-value: 3.64e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627  31 HKKAKITLVD-RNHsHLWKPLLHEVATGSLdEGVDALSYLAHARNH-GFQFQLGSVVDINREGKTITLGELRNEKGELlV 108
Cdd:PTZ00318   31 PKKYNITVISpRNH-MLFTPLLPQTTTGTL-EFRSICEPVRPALAKlPNRYLRAVVYDVDFEEKRVKCGVVSKSNNAN-V 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 109 AERKLPYDTLVMALGSTSNDFNTPGVKENCIFLDNPHQARRFHQEMLNLFLKysANLG------ANGKVNIAIVGGGATG 182
Cdd:PTZ00318  108 NTFSVPYDKLVVAHGARPNTFNIPGVEERAFFLKEVNHARGIRKRIVQCIER--ASLPttsveeRKRLLHFVVVGGGPTG 185

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 183 VELSAELHNAVKQLHSYGYKGLTNEAlNVTLVEAGERILPALPPRISGAAHNELTKLGVRVLTQTMVTSADAGGLHTKDG 262
Cdd:PTZ00318  186 VEFAAELADFFRDDVRNLNPELVEEC-KVTVLEAGSEVLGSFDQALRKYGQRRLRRLGVDIRTKTAVKEVLDKEVVLKDG 264

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 263 EYIEADLMVWAAGIKAPDFMKEIGGLETNRiNQLVVEPTLQTTRDADIFAIGDCASCarpEGGFVPPRAQAAHQMATCAL 342
Cdd:PTZ00318  265 EVIPTGLVVWSTGVGPGPLTKQLKVDKTSR-GRISVDDHLRVKPIPNVFALGDCAAN---EERPLPTLAQVASQQGVYLA 340

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 343 NNILAQMKGKPL-KAYTYKDHGSLVSLSNYSTVGSLmgnlmrGSMMVEGRIARFVYISLY 401
Cdd:PTZ00318  341 KEFNNELKGKPMsKPFVYRSLGSLAYLGNYSAIVQL------GAFDLSGFKALLFWRSAY 394
Nterm_to_SelD TIGR03169
pyridine nucleotide-disulfide oxidoreductase family protein; Members of this protein family ...
 72-391 2.77e-40

pyridine nucleotide-disulfide oxidoreductase family protein; Members of this protein family include N-terminal sequence regions of (probable) bifunctional proteins whose C-terminal sequences are SelD, or selenide,water dikinase, the selenium donor protein necessary for selenium incorporation into protein (as selenocysteine), tRNA (as 2-selenouridine), or both. However, some members of this family occur in species that do not show selenium incorporation, and the function of this protein family is unknown.


Pssm-ID: 274465  Cd Length: 364  Bit Score: 147.35  E-value: 2.77e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627  72 ARNHGFQFQLGSVVDINREGKTITLgelrnEKGellvaeRKLPYDTLVMALGSTSNDFNTPGVKENCI-------FLDNP 144
Cdd:TIGR03169  64 ARFAGARLILDRAIGLDLAAKQVIC-----AGR------PPIAYDVLSIDIGSTPALPDVPGFAEHAIpakplgqFAQRW 132

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 145 HQarrfhqemlnlflkYSANLGANGKVNIAIVGGGATGVELSAELHNAVKQLHSygykgltneALNVTLVEAGERILPAL 224
Cdd:TIGR03169 133 QR--------------FLERAKPQQPPRIAVIGGGAAGVELALAMAHRLRQLGR---------NAEVTLIDRGNVLLPGH 189

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 225 PPRISGAAHNELTKLGVRVLTQTMVTSADAGGLHTKDGEYIEADLMVWAAGIKAPDFMKEIGgLETNRINQLVVEPTLQT 304
Cdd:TIGR03169 190 NARVRRRLERALQERGVTLHLGATVAEVTADAVRLEDGQTLPADFTFWATGARPPGWLAESG-LALDEDGFIRVGPTLQS 268

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 305 TRDADIFAIGDCAScarpeggFVP-PRAQA---AHQMATCALNNILAQMKGKPLKAYT-YKDHGSLVSLSNYSTVGSlmg 379
Cdd:TIGR03169 269 LSHPDIFAAGDCAH-------LVHaPRPKAgvfAVRQAPVLAENLRAALTGGPLRPYRpQSDYLKLISTGDKSAVAS--- 338

                         330
                  ....*....|..
gi 1460644627 380 nlmRGSMMVEGR 391
Cdd:TIGR03169 339 ---RGGLAFSGA 347
FadH2 COG0446
NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase ...
 30-355 2.18e-37

NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase [Lipid transport and metabolism];


Pssm-ID: 440215 [Multi-domain]  Cd Length: 322  Bit Score: 138.41  E-value: 2.18e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627  30 RHKKAKITLVDRNHSH------LWKPLLHEVATgsldegVDALSYLAHA--RNHGFQFQLGS-VVDINREGKTITLgelr 100
Cdd:COG0446     2 LGPDAEITVIEKGPHHsyqpcgLPYYVGGGIKD------PEDLLVRTPEsfERKGIDVRTGTeVTAIDPEAKTVTL---- 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 101 nEKGEllvaerKLPYDTLVMALGSTSNDFNTPGVKENCIF-LDNPHQARRFHQEMLNlflkysanlgANGKvNIAIVGGG 179
Cdd:COG0446    72 -RDGE------TLSYDKLVLATGARPRPPPIPGLDLPGVFtLRTLDDADALREALKE----------FKGK-RAVVIGGG 133

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 180 ATGVELSAELHNAvkqlhsygykGLtnealNVTLVEAGERILPALPPRISGAAHNELTKLGVRVLTQTMVTSADAGG--- 256
Cdd:COG0446   134 PIGLELAEALRKR----------GL-----KVTLVERAPRLLGVLDPEMAALLEEELREHGVELRLGETVVAIDGDDkva 198

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 257 LHTKDGEYIEADLMVWAAGIkAPDFmkEIG---GLETNRINQLVVEPTLQtTRDADIFAIGDCASCARPEGG--FVPPRA 331
Cdd:COG0446   199 VTLTDGEEIPADLVVVAPGV-RPNT--ELAkdaGLALGERGWIKVDETLQ-TSDPDVYAAGDCAEVPHPVTGktVYIPLA 274

                         330       340
                  ....*....|....*....|....
gi 1460644627 332 QAAHQMATCALNNILaqmkGKPLK 355
Cdd:COG0446   275 SAANKQGRVAAENIL----GGPAP 294
NirB COG1251
NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];
48-346 1.04e-34

NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];


Pssm-ID: 440863 [Multi-domain]  Cd Length: 402  Bit Score: 132.96  E-value: 1.04e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627  48 KPLLHEVATGSLDEGVDALSYLAHARNHGFQFQLGS-VVDINREGKTITLgelrnEKGEllvaerKLPYDTLVMALGSTS 126
Cdd:COG1251    42 RPPLSKVLAGETDEEDLLLRPADFYEENGIDLRLGTrVTAIDRAARTVTL-----ADGE------TLPYDKLVLATGSRP 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 127 NDFNTPGV-KENCIFLDNPHQARRFHQEMlnlflkysanlgANGKvNIAIVGGGATGVELSAELHNAvkqlhsyGYKglt 205
Cdd:COG1251   111 RVPPIPGAdLPGVFTLRTLDDADALRAAL------------APGK-RVVVIGGGLIGLEAAAALRKR-------GLE--- 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 206 nealnVTLVEAGERILP-ALPPRISGAAHNELTKLGVRVLTQTMVTS----ADAGGLHTKDGEYIEADLMVWAAGIKaP- 279
Cdd:COG1251   168 -----VTVVERAPRLLPrQLDEEAGALLQRLLEALGVEVRLGTGVTEiegdDRVTGVRLADGEELPADLVVVAIGVR-Pn 241

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 280 -DFMKEIGgLETNR-InqlVVEPTLQTTrDADIFAIGDCASCA-RPEGGFVPPRAQAAHQMATCALNNIL 346
Cdd:COG1251   242 tELARAAG-LAVDRgI---VVDDYLRTS-DPDIYAAGDCAEHPgPVYGRRVLELVAPAYEQARVAAANLA 306
Lpd COG1249
Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex ...
 173-348 1.84e-19

Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase [Energy production and conversion]; Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase is part of the Pathway/BioSystem: Glycine cleavagePyruvate oxidation


Pssm-ID: 440861 [Multi-domain]  Cd Length: 456  Bit Score: 90.15  E-value: 1.84e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 173 IAIVGGGATGVEL-SAelhnavkqLHSYGYKgltnealnVTLVEAGERILPALPPRISGAAHNELTKLGVRVLTQTMVTS 251
Cdd:COG1249   171 LVVIGGGYIGLEFaQI--------FARLGSE--------VTLVERGDRLLPGEDPEISEALEKALEKEGIDILTGAKVTS 234

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 252 ADAGG----LHTKDG---EYIEADLMVWAAGIKApdFMKEIG----GLETNRINQLVVEPTLQTTrDADIFAIGDCAsca 320
Cdd:COG1249   235 VEKTGdgvtVTLEDGggeEAVEADKVLVATGRRP--NTDGLGleaaGVELDERGGIKVDEYLRTS-VPGIYAIGDVT--- 308

                         170       180
                  ....*....|....*....|....*...
gi 1460644627 321 rpeGGfvPPRAQAAHQMATCALNNILAQ 348
Cdd:COG1249   309 ---GG--PQLAHVASAEGRVAAENILGK 331
PRK04965 PRK04965
NADH:flavorubredoxin reductase NorW;
84-348 6.44e-19

NADH:flavorubredoxin reductase NorW;


Pssm-ID: 179902 [Multi-domain]  Cd Length: 377  Bit Score: 87.66  E-value: 6.44e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627  84 VVDINREGKTITlgelrnekgellVAERKLPYDTLVMALGSTSndFNTPGVKENCIFLDNPHQARRFHQEMLnlflkysa 163
Cdd:PRK04965   81 VTDIDAEAQVVK------------SQGNQWQYDKLVLATGASA--FVPPIPGRELMLTLNSQQEYRAAETQL-------- 138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 164 nlgANGKvNIAIVGGGATGVELSAELHNAVKQlhsygykgltnealnVTLVEAGERILPAL-PPRISGAAHNELTKLGVR 242
Cdd:PRK04965  139 ---RDAQ-RVLVVGGGLIGTELAMDLCRAGKA---------------VTLVDNAASLLASLmPPEVSSRLQHRLTEMGVH 199

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 243 VLTQTMV---TSADAG-GLHTKDGEYIEADLMVWAAGIKAPDFMKEIGGLETNRinQLVVEPTLQTTrDADIFAIGDCAS 318
Cdd:PRK04965  200 LLLKSQLqglEKTDSGiRATLDSGRSIEVDAVIAAAGLRPNTALARRAGLAVNR--GIVVDSYLQTS-APDIYALGDCAE 276

                         250       260       270
                  ....*....|....*....|....*....|
gi 1460644627 319 CarpeGGFVPPRAQAAHQMATCALNNILAQ 348
Cdd:PRK04965  277 I----NGQVLPFLQPIQLSAMALAKNLLGQ 302
nitri_red_nirB TIGR02374
nitrite reductase [NAD(P)H], large subunit; [Central intermediary metabolism, Nitrogen ...
 50-357 2.53e-18

nitrite reductase [NAD(P)H], large subunit; [Central intermediary metabolism, Nitrogen metabolism]


Pssm-ID: 162827 [Multi-domain]  Cd Length: 785  Bit Score: 87.58  E-value: 2.53e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627  50 LLHEVATGSLDEGVDALSYLAHARNHGFQFQLG-SVVDINREGKTItlgelrnekgeLLVAERKLPYDTLVMALGSTSND 128
Cdd:TIGR02374  42 LLSSVLQGEADLDDITLNSKDWYEKHGITLYTGeTVIQIDTDQKQV-----------ITDAGRTLSYDKLILATGSYPFI 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 129 FNTPGV-KENCifldnpHQARRFH--QEMLNlflkysanlGANGKVNIAIVGGGATGVELSaelhnavkqlhsygyKGLT 205
Cdd:TIGR02374 111 LPIPGAdKKGV------YVFRTIEdlDAIMA---------MAQRFKKAAVIGGGLLGLEAA---------------VGLQ 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 206 NEALNVTLVEAGERILPALPPRISGAA-HNELTKLGVRVLTQT----MVTSADAGGLHTKDGEYIEADLMVWAAGIKAPD 280
Cdd:TIGR02374 161 NLGMDVSVIHHAPGLMAKQLDQTAGRLlQRELEQKGLTFLLEKdtveIVGATKADRIRFKDGSSLEADLIVMAAGIRPND 240

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1460644627 281 FMKEIGGLETNRinQLVVEPTLQTTrDADIFAIGDCASCARPEGGFVPPraqaAHQMATCALNNILaqmkGKPLKAY 357
Cdd:TIGR02374 241 ELAVSAGIKVNR--GIIVNDSMQTS-DPDIYAVGECAEHNGRVYGLVAP----LYEQAKVLADHIC----GVECEEY 306
PRK09564 PRK09564
coenzyme A disulfide reductase; Reviewed
 84-318 1.48e-14

coenzyme A disulfide reductase; Reviewed


Pssm-ID: 181958 [Multi-domain]  Cd Length: 444  Bit Score: 75.08  E-value: 1.48e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627  84 VVDINREGKTITLGELRNEKgellvaERKLPYDTLVMALGSTSNdfnTPGVKEncIFLDNPHQARRFH--QEMLNLFLKY 161
Cdd:PRK09564   79 VVKVDAKNKTITVKNLKTGS------IFNDTYDKLMIATGARPI---IPPIKN--INLENVYTLKSMEdgLALKELLKDE 147

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 162 SanlgangKVNIAIVGGGATGVELSAELHNAVKqlhsygykgltnealNVTLVEAGERILP-ALPPRISGAAHNELTKLG 240
Cdd:PRK09564  148 E-------IKNIVIIGAGFIGLEAVEAAKHLGK---------------NVRIIQLEDRILPdSFDKEITDVMEEELRENG 205

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 241 VRVLTQTMVTSADAG----GLHTKDGEYiEADLMVWAAGIK-APDFMKEiGGLETNRINQLVVEPTLQTTrDADIFAIGD 315
Cdd:PRK09564  206 VELHLNEFVKSLIGEdkveGVVTDKGEY-EADVVIVATGVKpNTEFLED-TGLKTLKNGAIIVDEYGETS-IENIYAAGD 282


                  ...
gi 1460644627 316 CAS 318
Cdd:PRK09564  283 CAT 285
PRK06416 PRK06416
dihydrolipoamide dehydrogenase; Reviewed
 173-315 1.08e-11

dihydrolipoamide dehydrogenase; Reviewed


Pssm-ID: 235798 [Multi-domain]  Cd Length: 462  Bit Score: 66.32  E-value: 1.08e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 173 IAIVGGGATGVEL-SAelhnavkqlhsygYKGLTNEalnVTLVEAGERILPALPPRISGAAHNELTKLGVRVLTQTMVTS 251
Cdd:PRK06416  175 LVVIGGGYIGVEFaSA-------------YASLGAE---VTIVEALPRILPGEDKEISKLAERALKKRGIKIKTGAKAKK 238

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1460644627 252 ADAGG----LHTKDG---EYIEADLMVWAAGIkAPDfMKEIG----GLETNRiNQLVVEPTLQTTrDADIFAIGD 315
Cdd:PRK06416  239 VEQTDdgvtVTLEDGgkeETLEADYVLVAVGR-RPN-TENLGleelGVKTDR-GFIEVDEQLRTN-VPNIYAIGD 309
PRK06292 PRK06292
dihydrolipoamide dehydrogenase; Validated
 173-316 2.04e-11

dihydrolipoamide dehydrogenase; Validated


Pssm-ID: 235774 [Multi-domain]  Cd Length: 460  Bit Score: 65.58  E-value: 2.04e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 173 IAIVGGGATGVEL-SAelhnavkqLHSYGYKgltnealnVTLVEAGERILPALPPRISGAAHNELTKlGVRVLTQTMVTS 251
Cdd:PRK06292  172 LAVIGGGVIGLELgQA--------LSRLGVK--------VTVFERGDRILPLEDPEVSKQAQKILSK-EFKIKLGAKVTS 234

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1460644627 252 ADAGG-----LHTKDGE--YIEADLMVWAAGIKA--PDFMKEIGGLETNRINQLVVEPTLQTTrDADIFAIGDC 316
Cdd:PRK06292  235 VEKSGdekveELEKGGKteTIEADYVLVATGRRPntDGLGLENTGIELDERGRPVVDEHTQTS-VPGIYAAGDV 307
Pyr_redox pfam00070
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 172-256 9.24e-11

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 425450 [Multi-domain]  Cd Length: 80  Bit Score: 57.60  E-value: 9.24e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 172 NIAIVGGGATGVELSAELHNAVKQlhsygykgltnealnVTLVEAGERILPALPPRISGAAHNELTKLGVRVLTQTMVTS 251
Cdd:pfam00070   1 RVVVVGGGYIGLELAGALARLGSK---------------VTVVERRDRLLPGFDPEIAKILQEKLEKNGIEFLLNTTVEA 65


                  ....*
gi 1460644627 252 ADAGG 256
Cdd:pfam00070  66 IEGNG 70
GltD COG0493
NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport ...
 73-318 1.77e-10

NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport and metabolism, General function prediction only]; NADPH-dependent glutamate synthase beta chain or related oxidoreductase is part of the Pathway/BioSystem: Glutamine biosynthesis


Pssm-ID: 440259 [Multi-domain]  Cd Length: 434  Bit Score: 62.46  E-value: 1.77e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627  73 RNHGFQFQLGSVVdinreGKTITLGELRNEkgellvaerklpYDTLVMALGST-SNDFNTPGvkENcifLDNPHQArrfh 151
Cdd:COG0493   182 EALGVEFRTNVEV-----GKDITLDELLEE------------FDAVFLATGAGkPRDLGIPG--ED---LKGVHSA---- 235

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 152 qemlNLFLKySANLG-------ANGKvNIAIVGGGATGVelsaelhNAVKQLHSYGykgltneALNVTLV---------- 214
Cdd:COG0493   236 ----MDFLT-AVNLGeapdtilAVGK-RVVVIGGGNTAM-------DCARTALRLG-------AESVTIVyrrtreempa 295

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 215 ----------EAGERILPALPPRISGAAHNELTklGVRVLTQTMVTSADAGGLHTKDGE----YIEADLMVWAAGIKA-P 279
Cdd:COG0493   296 skeeveealeEGVEFLFLVAPVEIIGDENGRVT--GLECVRMELGEPDESGRRRPVPIEgsefTLPADLVILAIGQTPdP 373

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 1460644627 280 DFMKEIGGLETNRINQLVVEP-TLQTTRDaDIFAIGDCAS 318
Cdd:COG0493   374 SGLEEELGLELDKRGTIVVDEeTYQTSLP-GVFAGGDAVR 412
PRK14989 PRK14989
nitrite reductase subunit NirD; Provisional
 75-348 2.56e-10

nitrite reductase subunit NirD; Provisional


Pssm-ID: 184951 [Multi-domain]  Cd Length: 847  Bit Score: 62.44  E-value: 2.56e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627  75 HGFQFQLGS-VVDINREGKTItlgelRNEKGellvaeRKLPYDTLVMALGSTSNdfnTPGVKenciflDNPHQARRFHQE 153
Cdd:PRK14989   72 HGIKVLVGErAITINRQEKVI-----HSSAG------RTVFYDKLIMATGSYPW---IPPIK------GSETQDCFVYRT 131

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 154 MLNL-FLKYSANLGANGkvniAIVGGGATGVELSAelhnAVKQLhsygykGLTNEALNVTLVEAGERilpaLPPRISGAA 232
Cdd:PRK14989  132 IEDLnAIEACARRSKRG----AVVGGGLLGLEAAG----ALKNL------GVETHVIEFAPMLMAEQ----LDQMGGEQL 193

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 233 HNELTKLGVRVLTQTMVTSADAGG------LHTKDGEYIEADLMVWAAGIKAPDFMKEIGGLETNRINQLVVEPTLQTTr 306
Cdd:PRK14989  194 RRKIESMGVRVHTSKNTLEIVQEGvearktMRFADGSELEVDFIVFSTGIRPQDKLATQCGLAVAPRGGIVINDSCQTS- 272

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 1460644627 307 DADIFAIGDCASCARPEGGFVPPraqaAHQMATCALNNILAQ 348
Cdd:PRK14989  273 DPDIYAIGECASWNNRVFGLVAP----GYKMAQVAVDHLLGS 310
PRK09754 PRK09754
phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional
 78-324 3.10e-10

phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional


Pssm-ID: 170080 [Multi-domain]  Cd Length: 396  Bit Score: 61.48  E-value: 3.10e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627  78 QFQLGSVVDInREGKTI-TLGelRNEKGELLVAERKLPYDTLVMALGSTSNDFNT-PGVKENCIFLDNPHQARRFHQEMl 155
Cdd:PRK09754   66 NWWQENNVHL-HSGVTIkTLG--RDTRELVLTNGESWHWDQLFIATGAAARPLPLlDALGERCFTLRHAGDAARLREVL- 141

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 156 nlflkysanlgANGKvNIAIVGGGATGVELSAElhnavkqlhsygykgLTNEALNVTLVEAGERIL-PALPPRISGAAHN 234
Cdd:PRK09754  142 -----------QPER-SVVIVGAGTIGLELAAS---------------ATQRRCKVTVIELAATVMgRNAPPPVQRYLLQ 194

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 235 ELTKLGVRVLTQTMVTSADAGG---LHTKDGEYIEADLMVWAAGIKAPDFMKEIGGLETNriNQLVVEPTLQTTrDADIF 311
Cdd:PRK09754  195 RHQQAGVRILLNNAIEHVVDGEkveLTLQSGETLQADVVIYGIGISANDQLAREANLDTA--NGIVIDEACRTC-DPAIF 271

                         250
                  ....*....|...
gi 1460644627 312 AIGDCASCARPEG 324
Cdd:PRK09754  272 AGGDVAITRLDNG 284
PRK06116 PRK06116
glutathione reductase; Validated
 173-316 2.79e-08

glutathione reductase; Validated


Pssm-ID: 235701 [Multi-domain]  Cd Length: 450  Bit Score: 55.55  E-value: 2.79e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 173 IAIVGGGATGVELSAELHnavkqlhsygykGLTNEalnVTLVEAGERILPALPPRISGAAHNELTKLGVRVLTQTMVTSA 252
Cdd:PRK06116  170 VAVVGAGYIAVEFAGVLN------------GLGSE---THLFVRGDAPLRGFDPDIRETLVEEMEKKGIRLHTNAVPKAV 234

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1460644627 253 DAGG-----LHTKDGEYIEADLMVWAAGiKAP---DFMKEIGGLETNRINQLVVEpTLQTTRDADIFAIGDC 316
Cdd:PRK06116  235 EKNAdgsltLTLEDGETLTVDCLIWAIG-REPntdGLGLENAGVKLNEKGYIIVD-EYQNTNVPGIYAVGDV 304
PRK05249 PRK05249
Si-specific NAD(P)(+) transhydrogenase;
173-315 3.12e-07

Si-specific NAD(P)(+) transhydrogenase;


Pssm-ID: 235373 [Multi-domain]  Cd Length: 461  Bit Score: 52.47  E-value: 3.12e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 173 IAIVGGGATGVElsaelhnavkqlhsY-------GYKgltnealnVTLVEAGERILPALPPRISGAAHNELTKLGVRVLT 245
Cdd:PRK05249  178 LIIYGAGVIGCE--------------YasifaalGVK--------VTLINTRDRLLSFLDDEISDALSYHLRDSGVTIRH 235

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1460644627 246 QTMVTSADAGG----LHTKDGEYIEADLMVWAAG-IKAPDFMK-EIGGLETNRINQLVVEPTLQTTRDaDIFAIGD 315
Cdd:PRK05249  236 NEEVEKVEGGDdgviVHLKSGKKIKADCLLYANGrTGNTDGLNlENAGLEADSRGQLKVNENYQTAVP-HIYAVGD 310
PRK06370 PRK06370
FAD-containing oxidoreductase;
173-316 2.87e-06

FAD-containing oxidoreductase;


Pssm-ID: 235787 [Multi-domain]  Cd Length: 463  Bit Score: 49.43  E-value: 2.87e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 173 IAIVGGGATGVELSaelhnavkqlhsYGYKGLTNEalnVTLVEAGERILPALPPRISGAAHNELTKLGVRVLTQTMVTSA 252
Cdd:PRK06370  174 LVIIGGGYIGLEFA------------QMFRRFGSE---VTVIERGPRLLPREDEDVAAAVREILEREGIDVRLNAECIRV 238

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1460644627 253 --DAGGL-----HTKDGEYIEADLMVWAAGiKAP---DFMKEIGGLETNRINQLVVEPTLQTTRDaDIFAIGDC 316
Cdd:PRK06370  239 erDGDGIavgldCNGGAPEITGSHILVAVG-RVPntdDLGLEAAGVETDARGYIKVDDQLRTTNP-GIYAAGDC 310
TrxB COG0492
Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];
70-318 1.50e-05

Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440258 [Multi-domain]  Cd Length: 305  Bit Score: 46.65  E-value: 1.50e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627  70 AHARNHGFQFQLGSVVDINREGKTITLgelRNEKGELLVAerklpyDTLVMALGSTSNDFNTPGVKE-------NCIFLD 142
Cdd:COG0492    65 EQAERFGAEILLEEVTSVDKDDGPFRV---TTDDGTEYEA------KAVIIATGAGPRKLGLPGEEEfegrgvsYCATCD 135

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 143 NPhqarrfhqemlnlFLKysanlganGKvNIAIVGGGATGVELSAElhnavkqlhsygykgLTNEALNVTLVEAGERIlp 222
Cdd:COG0492   136 GF-------------FFR--------GK-DVVVVGGGDSALEEALY---------------LTKFASKVTLIHRRDEL-- 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 223 alpprisGAAHNELTKL----GVRVLTQTMVTSADAGGL-------HTKDGE--YIEADLMVWAAGIKAP-DFMKEIgGL 288
Cdd:COG0492   177 -------RASKILVERLranpKIEVLWNTEVTEIEGDGRvegvtlkNVKTGEekELEVDGVFVAIGLKPNtELLKGL-GL 248

                         250       260       270
                  ....*....|....*....|....*....|
gi 1460644627 289 ETNRINQLVVEPTLQTTRDAdIFAIGDCAS 318
Cdd:COG0492   249 ELDEDGYIVVDEDMETSVPG-VFAAGDVRD 277
PRK12771 PRK12771
putative glutamate synthase (NADPH) small subunit; Provisional
 240-321 3.39e-04

putative glutamate synthase (NADPH) small subunit; Provisional


Pssm-ID: 237198 [Multi-domain]  Cd Length: 564  Bit Score: 42.94  E-value: 3.39e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 240 GVRVLTQTMVTSADAGGLHTKDGEY--IEADLMVWAAGiKAPD--FMKEIGGLETNRiNQLVVEPTLQTTRDADIFAIGD 315
Cdd:PRK12771  340 GLRVITVEKMELDEDGRPSPVTGEEetLEADLVVLAIG-QDIDsaGLESVPGVEVGR-GVVQVDPNFMMTGRPGVFAGGD 417


                  ....*.
gi 1460644627 316 CASCAR 321
Cdd:PRK12771  418 MVPGPR 423
PRK12770 PRK12770
putative glutamate synthase subunit beta; Provisional
 173-315 1.40e-03

putative glutamate synthase subunit beta; Provisional


Pssm-ID: 237197 [Multi-domain]  Cd Length: 352  Bit Score: 40.74  E-value: 1.40e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 173 IAIVGGGATGVE--LSAELHNAVKQLHSYgyKGLTNEA------LNvTLVEAG----ERILPAlppRISGaahnELTKLG 240
Cdd:PRK12770  175 VVVVGAGLTAVDaaLEAVLLGAEKVYLAY--RRTINEApagkyeIE-RLIARGveflELVTPV---RIIG----EGRVEG 244

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 241 VRvLTQTMVTSADAGGLH----TKDGEY-IEADLMVWAAG-IKAPDFMKEIGGLETNRINQLVVEPTLQTTRdADIFAIG 314
Cdd:PRK12770  245 VE-LAKMRLGEPDESGRPrpvpIPGSEFvLEADTVVFAIGeIPTPPFAKECLGIELNRKGEIVVDEKHMTSR-EGVFAAG 322


                  .
gi 1460644627 315 D 315
Cdd:PRK12770  323 D 323
PRK13748 PRK13748
putative mercuric reductase; Provisional
 222-316 2.94e-03

putative mercuric reductase; Provisional


Pssm-ID: 184298 [Multi-domain]  Cd Length: 561  Bit Score: 39.75  E-value: 2.94e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 222 PALPPRISGAAHNEltklGVRVLTQTMVTS-ADAGG---LHTKDGEyIEADLMVWAAGiKAPDFMK---EIGGLETNRIN 294
Cdd:PRK13748  310 PAIGEAVTAAFRAE----GIEVLEHTQASQvAHVDGefvLTTGHGE-LRADKLLVATG-RAPNTRSlalDAAGVTVNAQG 383

                          90       100
                  ....*....|....*....|..
gi 1460644627 295 QLVVEPTLQTTRdADIFAIGDC 316
Cdd:PRK13748  384 AIVIDQGMRTSV-PHIYAAGDC 404
TrxB COG0492
Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];
173-278 3.09e-03

Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440258 [Multi-domain]  Cd Length: 305  Bit Score: 39.33  E-value: 3.09e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 173 IAIVGGGATGveLSAelhnAVkqlhsygYKGLTNeaLNVTLVEAGE---------RI--LPALPPRISGA-----AHNEL 236
Cdd:COG0492     3 VVIIGAGPAG--LTA----AI-------YAARAG--LKTLVIEGGEpggqlattkEIenYPGFPEGISGPelaerLREQA 67

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1460644627 237 TKLGVRVLTqTMVTSADAGG----LHTKDGEYIEADLMVWAAGIKA 278
Cdd:COG0492    68 ERFGAEILL-EEVTSVDKDDgpfrVTTDDGTEYEAKAVIIATGAGP 112
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
187-286 4.76e-03

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 39.12  E-value: 4.76e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 187 AELHNAVKQLHSYGYKgltnealnVTLVEAGE--RILPAL-PPRISGAAHNE-----------------LTKLGVRVLTQ 246
Cdd:COG0665   100 AALRAEAEALRALGLP--------VELLDAAElrEREPGLgSPDYAGGLYDPddghvdpaklvralaraARAAGVRIREG 171

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1460644627 247 TMVTSADAGG-----LHTKDGEyIEADLMVWAAGIKAPDFMKEIG 286
Cdd:COG0665   172 TPVTGLEREGgrvtgVRTERGT-VRADAVVLAAGAWSARLLPMLG 215
PRK08010 PRK08010
pyridine nucleotide-disulfide oxidoreductase; Provisional
 173-315 6.08e-03

pyridine nucleotide-disulfide oxidoreductase; Provisional


Pssm-ID: 181196 [Multi-domain]  Cd Length: 441  Bit Score: 38.84  E-value: 6.08e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1460644627 173 IAIVGGGATGVELSAELHNavkqlhsYGYKgltnealnVTLVEAGERILPALPPRISGAAHNELTKLGVRVL----TQTM 248
Cdd:PRK08010  161 LGILGGGYIGVEFASMFAN-------FGSK--------VTILEAASLFLPREDRDIADNIATILRDQGVDIIlnahVERI 225

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1460644627 249 VTSADAGGLHTKDGEYIeADLMVWAAGIK--APDFMKEIGGLETNRINQLVVEPTLQTTRDaDIFAIGD 315
Cdd:PRK08010  226 SHHENQVQVHSEHAQLA-VDALLIASGRQpaTASLHPENAGIAVNERGAIVVDKYLHTTAD-NIWAMGD 292
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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