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Conserved domains on  [gi|1462843241|emb|SXF32750|]
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nitrate/sulfonate/bicarbonate ABC transporter ATPase [Klebsiella variicola]

Protein Classification

P-loop NTPase family protein( domain architecture ID 1562424)

P-loop NTPase (nucleoside triphosphate hydrolase) family protein contains two conserved sequence signatures, the Walker A motif (the P-loop proper) and Walker B motif which bind, respectively, the beta and gamma phosphate moieties of the bound nucleotide (typically ATP or GTP), and a Mg(2+) cation

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TauB super family cl43334
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ...
 1-138 2.10e-58

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];


The actual alignment was detected with superfamily member COG1116:

Pssm-ID: 440733 [Multi-domain]  Cd Length: 260  Bit Score: 181.44  E-value: 2.10e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   1 MDMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERvinTRSMLLVT 80
Cdd:COG1116   120 RELLELVGLAGFEDAYPHQLSGGMRQRVAIARALANDPEVLLMDEPFGALDALTRERLQDELLRLWQET---GKTVLFVT 196

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1462843241  81 HSVEEAVMLSDRVCLLGGLPSTITDTFDIDIKR----NQRTKESISSLVEKISTTLNERIAA 138
Cdd:COG1116   197 HDVDEAVFLADRVVVLSARPGRIVEEIDVDLPRprdrELRTSPEFAALRAEILDLLREEAER 258
 
Name Accession Description Interval E-value
TauB COG1116
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ...
 1-138 2.10e-58

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440733 [Multi-domain]  Cd Length: 260  Bit Score: 181.44  E-value: 2.10e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   1 MDMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERvinTRSMLLVT 80
Cdd:COG1116   120 RELLELVGLAGFEDAYPHQLSGGMRQRVAIARALANDPEVLLMDEPFGALDALTRERLQDELLRLWQET---GKTVLFVT 196

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1462843241  81 HSVEEAVMLSDRVCLLGGLPSTITDTFDIDIKR----NQRTKESISSLVEKISTTLNERIAA 138
Cdd:COG1116   197 HDVDEAVFLADRVVVLSARPGRIVEEIDVDLPRprdrELRTSPEFAALRAEILDLLREEAER 258
ABC_NrtD_SsuB_transporters cd03293
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...
 1-111 9.81e-56

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213260 [Multi-domain]  Cd Length: 220  Bit Score: 173.43  E-value: 9.81e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   1 MDMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEErviNTRSMLLVT 80
Cdd:cd03293   113 EELLELVGLSGFENAYPHQLSGGMRQRVALARALAVDPDVLLLDEPFSALDALTREQLQEELLDIWRE---TGKTVLLVT 189

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1462843241  81 HSVEEAVMLSDRVCLLGGLPSTITDTFDIDI 111
Cdd:cd03293   190 HDIDEAVFLADRVVVLSARPGRIVAEVEVDL 220
tauB PRK11248
taurine ABC transporter ATP-binding subunit;
2-124 1.36e-32

taurine ABC transporter ATP-binding subunit;


Pssm-ID: 183056 [Multi-domain]  Cd Length: 255  Bit Score: 115.18  E-value: 1.36e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEErviNTRSMLLVTH 81
Cdd:PRK11248  111 QMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGALDAFTREQMQTLLLKLWQE---TGKQVLLITH 187

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1462843241  82 SVEEAVMLSDRVCLLGGLPSTITDTFDIDIKRNQRTKESISSL 124
Cdd:PRK11248  188 DIEEAVFMATELVLLSPGPGRVVERLPLNFARRFVAGESSRSI 230
ntrCD TIGR01184
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ...
 2-113 6.19e-31

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]


Pssm-ID: 130252 [Multi-domain]  Cd Length: 230  Bit Score: 110.25  E-value: 6.19e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEErviNTRSMLLVTH 81
Cdd:TIGR01184  97 EHIALVGLTEAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDALTRGNLQEELMQIWEE---HRVTVLMVTH 173

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1462843241  82 SVEEAVMLSDRVCLLGGLP-STITDTFDIDIKR 113
Cdd:TIGR01184 174 DVDEALLLSDRVVMLTNGPaANIGQILEVPFPR 206
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
2-96 3.17e-19

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 79.20  E-value: 3.17e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTgnklRQDLIELWEERVINTRSMLLVTH 81
Cdd:NF040873  102 DALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTGLDAES----RERIIALLAEEHARGATVVVVTH 177

                          90
                  ....*....|....*
gi 1462843241  82 SvEEAVMLSDRVCLL 96
Cdd:NF040873  178 D-LELVRRADPCVLL 191
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 2-48 1.09e-11

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 58.43  E-value: 1.09e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1462843241   2 DMLDLIGLTGYEK----AYPRELSGGMRQRVGFARALAVEPDLLLMDEPFS 48
Cdd:pfam00005 100 EALEKLGLGDLADrpvgERPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
2-96 2.00e-06

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 45.50  E-value: 2.00e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNklrqdliELWEE---RVINTRSMLL 78
Cdd:NF000106  127 ELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRN-------EVWDEvrsMVRDGATVLL 199

                          90
                  ....*....|....*...
gi 1462843241  79 VTHSVEEAVMLSDRVCLL 96
Cdd:NF000106  200 TTQYMEEAEQLAHELTVI 217
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
2-51 1.42e-05

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 43.19  E-value: 1.42e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALD 51
Cdd:NF033858  380 EMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTSGVD 429
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
20-46 8.20e-05

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 41.26  E-value: 8.20e-05
                          10        20
                  ....*....|....*....|....*..
gi 1462843241  20 LSGGMRQRVGFARALAVEPDLLLMDEP 46
Cdd:NF033858  137 LSGGMKQKLGLCCALIHDPDLLILDEP 163
 
Name Accession Description Interval E-value
TauB COG1116
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ...
 1-138 2.10e-58

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440733 [Multi-domain]  Cd Length: 260  Bit Score: 181.44  E-value: 2.10e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   1 MDMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERvinTRSMLLVT 80
Cdd:COG1116   120 RELLELVGLAGFEDAYPHQLSGGMRQRVAIARALANDPEVLLMDEPFGALDALTRERLQDELLRLWQET---GKTVLFVT 196

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1462843241  81 HSVEEAVMLSDRVCLLGGLPSTITDTFDIDIKR----NQRTKESISSLVEKISTTLNERIAA 138
Cdd:COG1116   197 HDVDEAVFLADRVVVLSARPGRIVEEIDVDLPRprdrELRTSPEFAALRAEILDLLREEAER 258
ABC_NrtD_SsuB_transporters cd03293
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...
 1-111 9.81e-56

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213260 [Multi-domain]  Cd Length: 220  Bit Score: 173.43  E-value: 9.81e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   1 MDMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEErviNTRSMLLVT 80
Cdd:cd03293   113 EELLELVGLSGFENAYPHQLSGGMRQRVALARALAVDPDVLLLDEPFSALDALTREQLQEELLDIWRE---TGKTVLLVT 189

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1462843241  81 HSVEEAVMLSDRVCLLGGLPSTITDTFDIDI 111
Cdd:cd03293   190 HDIDEAVFLADRVVVLSARPGRIVAEVEVDL 220
TauB COG4525
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
2-124 1.38e-39

ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443596 [Multi-domain]  Cd Length: 262  Bit Score: 133.45  E-value: 1.38e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEErviNTRSMLLVTH 81
Cdd:COG4525   117 ELLALVGLADFARRRIWQLSGGMRQRVGIARALAADPRFLLMDEPFGALDALTREQMQELLLDVWQR---TGKGVFLITH 193

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1462843241  82 SVEEAVMLSDRVCLLGGLPSTITDTFDIDIKRNQRTKESISSL 124
Cdd:COG4525   194 SVEEALFLATRLVVMSPGPGRIVERLELDFSRRFLAGEDARAI 236
CysA COG1118
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ...
 1-96 1.78e-37

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440735 [Multi-domain]  Cd Length: 348  Bit Score: 130.27  E-value: 1.78e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   1 MDMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVINTrsmLLVT 80
Cdd:COG1118   115 EELLELVQLEGLADRYPSQLSGGQRQRVALARALAVEPEVLLLDEPFGALDAKVRKELRRWLRRLHDELGGTT---VFVT 191

                          90
                  ....*....|....*.
gi 1462843241  81 HSVEEAVMLSDRVCLL 96
Cdd:COG1118   192 HDQEEALELADRVVVM 207
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 1-96 9.82e-36

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 125.60  E-value: 9.82e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   1 MDMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVIntrSMLLVT 80
Cdd:COG3842   117 AELLELVGLEGLADRYPHQLSGGQQQRVALARALAPEPRVLLLDEPLSALDAKLREEMREELRRLQRELGI---TFIYVT 193

                          90
                  ....*....|....*.
gi 1462843241  81 HSVEEAVMLSDRVCLL 96
Cdd:COG3842   194 HDQEEALALADRIAVM 209
ABC_Carb_Solutes_like cd03259
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...
 1-96 3.65e-34

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213226 [Multi-domain]  Cd Length: 213  Bit Score: 118.01  E-value: 3.65e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   1 MDMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVIntrSMLLVT 80
Cdd:cd03259   112 RELLELVGLEGLLNRYPHELSGGQQQRVALARALAREPSLLLLDEPLSALDAKLREELREELKELQRELGI---TTIYVT 188

                          90
                  ....*....|....*.
gi 1462843241  81 HSVEEAVMLSDRVCLL 96
Cdd:cd03259   189 HDQEEALALADRIAVM 204
ProV COG4175
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ...
 1-96 1.31e-32

ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443334 [Multi-domain]  Cd Length: 389  Bit Score: 118.28  E-value: 1.31e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   1 MDMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERvinTRSMLLVT 80
Cdd:COG4175   145 REALELVGLAGWEDSYPDELSGGMQQRVGLARALATDPDILLMDEAFSALDPLIRREMQDELLELQAKL---KKTIVFIT 221

                          90
                  ....*....|....*.
gi 1462843241  81 HSVEEAVMLSDRVCLL 96
Cdd:COG4175   222 HDLDEALRLGDRIAIM 237
tauB PRK11248
taurine ABC transporter ATP-binding subunit;
2-124 1.36e-32

taurine ABC transporter ATP-binding subunit;


Pssm-ID: 183056 [Multi-domain]  Cd Length: 255  Bit Score: 115.18  E-value: 1.36e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEErviNTRSMLLVTH 81
Cdd:PRK11248  111 QMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGALDAFTREQMQTLLLKLWQE---TGKQVLLITH 187

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1462843241  82 SVEEAVMLSDRVCLLGGLPSTITDTFDIDIKRNQRTKESISSL 124
Cdd:PRK11248  188 DIEEAVFMATELVLLSPGPGRVVERLPLNFARRFVAGESSRSI 230
ABC_Pro_Gly_Betaine cd03294
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ...
 1-96 3.00e-32

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213261 [Multi-domain]  Cd Length: 269  Bit Score: 114.66  E-value: 3.00e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   1 MDMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERvinTRSMLLVT 80
Cdd:cd03294   142 AEALELVGLEGWEHKYPDELSGGMQQRVGLARALAVDPDILLMDEAFSALDPLIRREMQDELLRLQAEL---QKTIVFIT 218

                          90
                  ....*....|....*.
gi 1462843241  81 HSVEEAVMLSDRVCLL 96
Cdd:cd03294   219 HDLDEALRLGDRIAIM 234
OpuBA COG1125
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ...
 1-96 5.15e-32

ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440742 [Multi-domain]  Cd Length: 306  Bit Score: 114.80  E-value: 5.15e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   1 MDMLDLIGL--TGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEErvINtRSMLL 78
Cdd:COG1125   116 DELLELVGLdpEEYRDRYPHELSGGQQQRVGVARALAADPPILLMDEPFGALDPITREQLQDELLRLQRE--LG-KTIVF 192

                          90
                  ....*....|....*...
gi 1462843241  79 VTHSVEEAVMLSDRVCLL 96
Cdd:COG1125   193 VTHDIDEALKLGDRIAVM 210
ntrCD TIGR01184
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ...
 2-113 6.19e-31

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]


Pssm-ID: 130252 [Multi-domain]  Cd Length: 230  Bit Score: 110.25  E-value: 6.19e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEErviNTRSMLLVTH 81
Cdd:TIGR01184  97 EHIALVGLTEAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDALTRGNLQEELMQIWEE---HRVTVLMVTH 173

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1462843241  82 SVEEAVMLSDRVCLLGGLP-STITDTFDIDIKR 113
Cdd:TIGR01184 174 DVDEALLLSDRVVMLTNGPaANIGQILEVPFPR 206
ABC_OpuCA_Osmoprotection cd03295
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...
 2-98 2.65e-30

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213262 [Multi-domain]  Cd Length: 242  Bit Score: 108.93  E-value: 2.65e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGL--TGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERvinTRSMLLV 79
Cdd:cd03295   116 ELLALVGLdpAEFADRYPHELSGGQQQRVGVARALAADPPLLLMDEPFGALDPITRDQLQEEFKRLQQEL---GKTIVFV 192

                          90
                  ....*....|....*....
gi 1462843241  80 THSVEEAVMLSDRVCLLGG 98
Cdd:cd03295   193 THDIDEAFRLADRIAIMKN 211
ABC_CysA_sulfate_importer cd03296
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...
 1-96 1.14e-28

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213263 [Multi-domain]  Cd Length: 239  Bit Score: 104.73  E-value: 1.14e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   1 MDMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVINTrsmLLVT 80
Cdd:cd03296   118 HELLKLVQLDWLADRYPAQLSGGQRQRVALARALAVEPKVLLLDEPFGALDAKVRKELRRWLRRLHDELHVTT---VFVT 194

                          90
                  ....*....|....*.
gi 1462843241  81 HSVEEAVMLSDRVCLL 96
Cdd:cd03296   195 HDQEEALEVADRVVVM 210
ABC_ModC_molybdenum_transporter cd03297
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...
 3-96 1.43e-28

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213264 [Multi-domain]  Cd Length: 214  Bit Score: 103.91  E-value: 1.43e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   3 MLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVIntrSMLLVTHS 82
Cdd:cd03297   115 LLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDRALRLQLLPELKQIKKNLNI---PVIFVTHD 191

                          90
                  ....*....|....
gi 1462843241  83 VEEAVMLSDRVCLL 96
Cdd:cd03297   192 LSEAEYLADRIVVM 205
ABC_PotA_N cd03300
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...
 1-96 9.32e-27

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213267 [Multi-domain]  Cd Length: 232  Bit Score: 99.62  E-value: 9.32e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   1 MDMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIftgnKLRQDL-IELweeRVINTR---SM 76
Cdd:cd03300   112 AEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPKVLLLDEPLGALDL----KLRKDMqLEL---KRLQKElgiTF 184

                          90       100
                  ....*....|....*....|
gi 1462843241  77 LLVTHSVEEAVMLSDRVCLL 96
Cdd:cd03300   185 VFVTHDQEEALTMSDRIAVM 204
ABC_Class3 cd03229
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...
 20-96 6.09e-25

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213196 [Multi-domain]  Cd Length: 178  Bit Score: 93.41  E-value: 6.09e-25
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1462843241  20 LSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVIntrSMLLVTHSVEEAVMLSDRVCLL 96
Cdd:cd03229   101 LSGGQQQRVALARALAMDPDVLLLDEPTSALDPITRREVRALLKSLQAQLGI---TVVLVTHDLDEAARLADRVVVL 174
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
2-96 7.51e-25

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 94.75  E-value: 7.51e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERvintRSMLLVTH 81
Cdd:COG1131   114 ELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPELLILDEPTSGLDPEARRELWELLRELAAEG----KTVLLSTH 189

                          90
                  ....*....|....*
gi 1462843241  82 SVEEAVMLSDRVCLL 96
Cdd:COG1131   190 YLEEAERLCDRVAII 204
ABC_Org_Solvent_Resistant cd03261
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...
 4-97 8.31e-25

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213228 [Multi-domain]  Cd Length: 235  Bit Score: 94.49  E-value: 8.31e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   4 LDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLrQDLIELWEERVINTrsMLLVTHSV 83
Cdd:cd03261   121 LEAVGLRGAEDLYPAELSGGMKKRVALARALALDPELLLYDEPTAGLDPIASGVI-DDLIRSLKKELGLT--SIMVTHDL 197

                          90
                  ....*....|....
gi 1462843241  84 EEAVMLSDRVCLLG 97
Cdd:cd03261   198 DTAFAIADRIAVLY 211
ThiQ COG3840
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
2-96 2.16e-24

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];


Pssm-ID: 443051 [Multi-domain]  Cd Length: 232  Bit Score: 93.28  E-value: 2.16e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFtgnkLRQDLIELWEERVINTR-SMLLVT 80
Cdd:COG3840   112 QALERVGLAGLLDRLPGQLSGGQRQRVALARCLVRKRPILLLDEPFSALDPA----LRQEMLDLVDELCRERGlTVLMVT 187

                          90
                  ....*....|....*.
gi 1462843241  81 HSVEEAVMLSDRVCLL 96
Cdd:COG3840   188 HDPEDAARIADRVLLV 203
MlaF COG1127
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...
 1-96 2.99e-24

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440744 [Multi-domain]  Cd Length: 241  Bit Score: 93.12  E-value: 2.99e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   1 MDMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLrQDLIelweeRVINTR---SML 77
Cdd:COG1127   123 LEKLELVGLPGAADKMPSELSGGMRKRVALARALALDPEILLYDEPTAGLDPITSAVI-DELI-----RELRDElglTSV 196

                          90
                  ....*....|....*....
gi 1462843241  78 LVTHSVEEAVMLSDRVCLL 96
Cdd:COG1127   197 VVTHDLDSAFAIADRVAVL 215
PRK10851 PRK10851
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
1-97 2.89e-23

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;


Pssm-ID: 182778 [Multi-domain]  Cd Length: 353  Bit Score: 92.84  E-value: 2.89e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   1 MDMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVINTrsmLLVT 80
Cdd:PRK10851  118 TQLLEMVQLAHLADRYPAQLSGGQKQRVALARALAVEPQILLLDEPFGALDAQVRKELRRWLRQLHEELKFTS---VFVT 194

                          90
                  ....*....|....*..
gi 1462843241  81 HSVEEAVMLSDRVCLLG 97
Cdd:PRK10851  195 HDQEEAMEVADRVVVMS 211
MalK COG3839
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ...
 2-96 4.66e-23

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];


Pssm-ID: 443050 [Multi-domain]  Cd Length: 352  Bit Score: 92.06  E-value: 4.66e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEErvINTrSMLLVTH 81
Cdd:COG3839   116 EAAELLGLEDLLDRKPKQLSGGQRQRVALGRALVREPKVFLLDEPLSNLDAKLRVEMRAEIKRLHRR--LGT-TTIYVTH 192

                          90
                  ....*....|....*
gi 1462843241  82 SVEEAVMLSDRVCLL 96
Cdd:COG3839   193 DQVEAMTLADRIAVM 207
ABC_MJ0796_LolCDE_FtsE cd03255
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...
 3-96 5.25e-23

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.


Pssm-ID: 213222 [Multi-domain]  Cd Length: 218  Bit Score: 89.47  E-value: 5.25e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   3 MLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERviNTrSMLLVTHS 82
Cdd:cd03255   124 LLERVGLGDRLNHYPSELSGGQQQRVAIARALANDPKIILADEPTGNLDSETGKEVMELLRELNKEA--GT-TIVVVTHD 200

                          90
                  ....*....|....
gi 1462843241  83 vEEAVMLSDRVCLL 96
Cdd:cd03255   201 -PELAEYADRIIEL 213
ModC COG4148
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ...
 2-96 1.16e-22

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443319 [Multi-domain]  Cd Length: 358  Bit Score: 90.93  E-value: 1.16e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDiftgNKLRQDLIELWeERVINTRS--MLLV 79
Cdd:COG4148   116 EVVELLGIGHLLDRRPATLSGGERQRVAIGRALLSSPRLLLMDEPLAALD----LARKAEILPYL-ERLRDELDipILYV 190

                          90
                  ....*....|....*..
gi 1462843241  80 THSVEEAVMLSDRVCLL 96
Cdd:COG4148   191 SHSLDEVARLADHVVLL 207
ssuB PRK11247
aliphatic sulfonates transport ATP-binding subunit; Provisional
 4-96 1.30e-22

aliphatic sulfonates transport ATP-binding subunit; Provisional


Pssm-ID: 183055 [Multi-domain]  Cd Length: 257  Bit Score: 89.35  E-value: 1.30e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   4 LDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLrQDLIE-LWEERVIntrSMLLVTHS 82
Cdd:PRK11247  118 LAAVGLADRANEWPAALSGGQKQRVALARALIHRPGLLLLDEPLGALDALTRIEM-QDLIEsLWQQHGF---TVLLVTHD 193

                          90
                  ....*....|....
gi 1462843241  83 VEEAVMLSDRVCLL 96
Cdd:PRK11247  194 VSEAVAMADRVLLI 207
EcfA2 COG1122
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...
 2-96 1.59e-22

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];


Pssm-ID: 440739 [Multi-domain]  Cd Length: 230  Bit Score: 88.54  E-value: 1.59e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVintrSMLLVTH 81
Cdd:COG1122   117 EALELVGLEHLADRPPHELSGGQKQRVAIAGVLAMEPEVLVLDEPTAGLDPRGRRELLELLKRLNKEGK----TVIIVTH 192

                          90
                  ....*....|....*
gi 1462843241  82 SVEEAVMLSDRVCLL 96
Cdd:COG1122   193 DLDLVAELADRVIVL 207
ABC_ModC_like cd03299
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ...
 16-96 1.60e-22

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213266 [Multi-domain]  Cd Length: 235  Bit Score: 88.55  E-value: 1.60e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  16 YPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEErviNTRSMLLVTHSVEEAVMLSDRVCL 95
Cdd:cd03299   126 KPETLSGGEQQRVAIARALVVNPKILLLDEPFSALDVRTKEKLREELKKIRKE---FGVTVLHVTHDFEEAWALADKVAI 202


                  .
gi 1462843241  96 L 96
Cdd:cd03299   203 M 203
potA TIGR01187
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ...
 1-98 1.77e-22

spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 162242 [Multi-domain]  Cd Length: 325  Bit Score: 90.25  E-value: 1.77e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   1 MDMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVINTrsmLLVT 80
Cdd:TIGR01187  82 LEALRLVQLEEFADRKPHQLSGGQQQRVALARALVFKPKILLLDEPLSALDKKLRDQMQLELKTIQEQLGITF---VFVT 158

                          90
                  ....*....|....*...
gi 1462843241  81 HSVEEAVMLSDRVCLLGG 98
Cdd:TIGR01187 159 HDQEEAMTMSDRIAIMRK 176
PRK10070 PRK10070
proline/glycine betaine ABC transporter ATP-binding protein ProV;
1-96 3.22e-22

proline/glycine betaine ABC transporter ATP-binding protein ProV;


Pssm-ID: 182221 [Multi-domain]  Cd Length: 400  Bit Score: 90.48  E-value: 3.22e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   1 MDMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELweeRVINTRSMLLVT 80
Cdd:PRK10070  146 LDALRQVGLENYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPLIRTEMQDELVKL---QAKHQRTIVFIS 222

                          90
                  ....*....|....*.
gi 1462843241  81 HSVEEAVMLSDRVCLL 96
Cdd:PRK10070  223 HDLDEAMRIGDRIAIM 238
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
 2-96 4.38e-22

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 90.35  E-value: 4.38e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGL-TGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVIntrSMLLVT 80
Cdd:COG1123   386 ELLERVGLpPDLADRYPHELSGGQRQRVAIARALALEPKLLILDEPTSALDVSVQAQILNLLRDLQRELGL---TYLFIS 462

                          90
                  ....*....|....*.
gi 1462843241  81 HSVEEAVMLSDRVCLL 96
Cdd:COG1123   463 HDLAVVRYIADRVAVM 478
ABC_HisP_GlnQ cd03262
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ...
 1-98 5.39e-22

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.


Pssm-ID: 213229 [Multi-domain]  Cd Length: 213  Bit Score: 86.81  E-value: 5.39e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   1 MDMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDiftgNKLRQDLIELWEERVINTRSMLLVT 80
Cdd:cd03262   117 LELLEKVGLADKADAYPAQLSGGQQQRVAIARALAMNPKVMLFDEPTSALD----PELVGEVLDVMKDLAEEGMTMVVVT 192

                          90
                  ....*....|....*...
gi 1462843241  81 HSVEEAVMLSDRVCLLGG 98
Cdd:cd03262   193 HEMGFAREVADRVIFMDD 210
ABC_NikE_OppD_transporters cd03257
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...
 1-93 6.65e-22

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.


Pssm-ID: 213224 [Multi-domain]  Cd Length: 228  Bit Score: 86.79  E-value: 6.65e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   1 MDMLDLIGL-TGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVIntrSMLLV 79
Cdd:cd03257   126 LLLLVGVGLpEEVLNRYPHELSGGQRQRVAIARALALNPKLLIADEPTSALDVSVQAQILDLLKKLQEELGL---TLLFI 202

                          90
                  ....*....|....
gi 1462843241  80 THSVEEAVMLSDRV 93
Cdd:cd03257   203 THDLGVVAKIADRV 216
ABC_MetN_methionine_transporter cd03258
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...
 2-96 8.76e-22

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213225 [Multi-domain]  Cd Length: 233  Bit Score: 86.87  E-value: 8.76e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVIntrSMLLVTH 81
Cdd:cd03258   123 ELLELVGLEDKADAYPAQLSGGQKQRVGIARALANNPKVLLCDEATSALDPETTQSILALLRDINRELGL---TIVLITH 199

                          90
                  ....*....|....*
gi 1462843241  82 SVEEAVMLSDRVCLL 96
Cdd:cd03258   200 EMEVVKRICDRVAVM 214
ABC_ATPase cd00267
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...
 19-96 9.92e-22

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213179 [Multi-domain]  Cd Length: 157  Bit Score: 84.60  E-value: 9.92e-22
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1462843241  19 ELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERvintRSMLLVTHSVEEAVMLSDRVCLL 96
Cdd:cd00267    80 QLSGGQRQRVALARALLLNPDLLLLDEPTSGLDPASRERLLELLRELAEEG----RTVIIVTHDPELAELAADRVIVL 153
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
 2-96 1.28e-21

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 89.19  E-value: 1.28e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVIntrSMLLVTH 81
Cdd:COG1123   125 ELLEAVGLERRLDRYPHQLSGGQRQRVAIAMALALDPDLLIADEPTTALDVTTQAEILDLLRELQRERGT---TVLLITH 201

                          90
                  ....*....|....*
gi 1462843241  82 SVEEAVMLSDRVCLL 96
Cdd:COG1123   202 DLGVVAEIADRVVVM 216
ZnuC COG1121
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 1-98 2.04e-21

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440738 [Multi-domain]  Cd Length: 245  Bit Score: 85.91  E-value: 2.04e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   1 MDMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTgnklRQDLIELWEERVINTRSMLLVT 80
Cdd:COG1121   121 DEALERVGLEDLADRPIGELSGGQQQRVLLARALAQDPDLLLLDEPFAGVDAAT----EEALYELLRELRREGKTILVVT 196

                          90
                  ....*....|....*...
gi 1462843241  81 HSVEEAVMLSDRVCLLGG 98
Cdd:COG1121   197 HDLGAVREYFDRVLLLNR 214
DppD COG0444
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 2-93 4.03e-21

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440213 [Multi-domain]  Cd Length: 320  Bit Score: 86.26  E-value: 4.03e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGLTGYE---KAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALD------IFtgnklrqDLI-ELWEERVI 71
Cdd:COG0444   130 ELLERVGLPDPErrlDRYPHELSGGMRQRVMIARALALEPKLLIADEPTTALDvtiqaqIL-------NLLkDLQRELGL 202

                          90       100
                  ....*....|....*....|..
gi 1462843241  72 ntrSMLLVTHSVEEAVMLSDRV 93
Cdd:COG0444   203 ---AILFITHDLGVVAEIADRV 221
ABC_DR_subfamily_A cd03230
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...
 9-96 6.39e-21

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213197 [Multi-domain]  Cd Length: 173  Bit Score: 82.83  E-value: 6.39e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   9 LTGYEKAyprELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTgnklRQDLIELWEERVINTRSMLLVTHSVEEAVM 88
Cdd:cd03230    88 LTVRENL---KLSGGMKQRLALAQALLHDPELLILDEPTSGLDPES----RREFWELLRELKKEGKTILLSSHILEEAER 160


                  ....*...
gi 1462843241  89 LSDRVCLL 96
Cdd:cd03230   161 LCDRVAIL 168
AbcC COG1135
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
1-51 6.98e-21

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440750 [Multi-domain]  Cd Length: 339  Bit Score: 85.90  E-value: 6.98e-21
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1462843241   1 MDMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALD 51
Cdd:COG1135   122 AELLELVGLSDKADAYPSQLSGGQKQRVGIARALANNPKVLLCDEATSALD 172
ABC_cobalt_CbiO_domain1 cd03225
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...
 2-96 9.27e-21

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213192 [Multi-domain]  Cd Length: 211  Bit Score: 83.67  E-value: 9.27e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERvintRSMLLVTH 81
Cdd:cd03225   117 EALELVGLEGLRDRSPFTLSGGQKQRVAIAGVLAMDPDILLLDEPTAGLDPAGRRELLELLKKLKAEG----KTIIIVTH 192

                          90
                  ....*....|....*
gi 1462843241  82 SVEEAVMLSDRVCLL 96
Cdd:cd03225   193 DLDLLLELADRVIVL 207
ABC_PstB_phosphate_transporter cd03260
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...
 4-96 1.67e-20

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).


Pssm-ID: 213227 [Multi-domain]  Cd Length: 227  Bit Score: 83.38  E-value: 1.67e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   4 LDLIGLTGYEK--AYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVIntrsmLLVTH 81
Cdd:cd03260   124 LRKAALWDEVKdrLHALGLSGGQQQRLCLARALANEPEVLLLDEPTSALDPISTAKIEELIAELKKEYTI-----VIVTH 198

                          90
                  ....*....|....*
gi 1462843241  82 SVEEAVMLSDRVCLL 96
Cdd:cd03260   199 NMQQAARVADRTAFL 213
anch_rpt_ABC TIGR03771
anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ...
 2-98 2.37e-20

anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ATP-binding cassette subunit of binding protein-dependent ABC transporter complex that strictly co-occurs with TIGR03769. TIGRFAMs model TIGR03769 describes a protein domain that occurs singly or as one of up to three repeats in proteins of a number of Actinobacteria, including Propionibacterium acnes KPA171202. The TIGR03769 domain occurs both in an adjacent gene for the substrate-binding protein and in additional (often nearby) proteins, often with LPXTG-like sortase recognition signals. Homologous ATP-binding subunits outside the scope of this family include manganese transporter MntA in Synechocystis sp. PCC 6803 and chelated iron transporter subunits. The function of this transporter complex is unknown. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 163483 [Multi-domain]  Cd Length: 223  Bit Score: 82.98  E-value: 2.37e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTgnklRQDLIELWEERVINTRSMLLVTH 81
Cdd:TIGR03771  96 DALRRVGLTELADRPVGELSGGQRQRVLVARALATRPSVLLLDEPFTGLDMPT----QELLTELFIELAGAGTAILMTTH 171

                          90
                  ....*....|....*..
gi 1462843241  82 SVEEAVMLSDRVCLLGG 98
Cdd:TIGR03771 172 DLAQAMATCDRVVLLNG 188
LolD COG1136
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
1-93 2.66e-20

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440751 [Multi-domain]  Cd Length: 227  Bit Score: 82.78  E-value: 2.66e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   1 MDMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERvinTRSMLLVT 80
Cdd:COG1136   126 RELLERVGLGDRLDHRPSQLSGGQQQRVAIARALVNRPKLILADEPTGNLDSKTGEEVLELLRELNREL---GTTIVMVT 202

                          90
                  ....*....|...
gi 1462843241  81 HSvEEAVMLSDRV 93
Cdd:COG1136   203 HD-PELAARADRV 214
NatA COG4555
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ...
 2-96 2.98e-20

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 443618 [Multi-domain]  Cd Length: 243  Bit Score: 82.98  E-value: 2.98e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERvintRSMLLVTH 81
Cdd:COG4555   115 ELIELLGLEEFLDRRVGELSTGMKKKVALARALVHDPKVLLLDEPTNGLDVMARRLLREILRALKKEG----KTVLFSSH 190

                          90
                  ....*....|....*
gi 1462843241  82 SVEEAVMLSDRVCLL 96
Cdd:COG4555   191 IMQEVEALCDRVVIL 205
PRK11264 PRK11264
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
 3-93 3.59e-20

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional


Pssm-ID: 183063 [Multi-domain]  Cd Length: 250  Bit Score: 82.88  E-value: 3.59e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   3 MLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERvintRSMLLVTHS 82
Cdd:PRK11264  128 LLAKVGLAGKETSYPRRLSGGQQQRVAIARALAMRPEVILFDEPTSALDPELVGEVLNTIRQLAQEK----RTMVIVTHE 203

                          90
                  ....*....|.
gi 1462843241  83 VEEAVMLSDRV 93
Cdd:PRK11264  204 MSFARDVADRA 214
ABC_Metallic_Cations cd03235
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...
 4-98 4.72e-20

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.


Pssm-ID: 213202 [Multi-domain]  Cd Length: 213  Bit Score: 81.81  E-value: 4.72e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   4 LDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDiftgNKLRQDLIELWEERVINTRSMLLVTHSV 83
Cdd:cd03235   117 LERVGLSELADRQIGELSGGQQQRVLLARALVQDPDLLLLDEPFAGVD----PKTQEDIYELLRELRREGMTILVVTHDL 192

                          90
                  ....*....|....*
gi 1462843241  84 EEAVMLSDRVCLLGG 98
Cdd:cd03235   193 GLVLEYFDRVLLLNR 207
GlnQ COG1126
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ...
 1-96 5.20e-20

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440743 [Multi-domain]  Cd Length: 239  Bit Score: 81.96  E-value: 5.20e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   1 MDMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALD-IFTGNKLrqDLI-ELWEERvintRSMLL 78
Cdd:COG1126   118 MELLERVGLADKADAYPAQLSGGQQQRVAIARALAMEPKVMLFDEPTSALDpELVGEVL--DVMrDLAKEG----MTMVV 191

                          90
                  ....*....|....*...
gi 1462843241  79 VTHSVEEAVMLSDRVCLL 96
Cdd:COG1126   192 VTHEMGFAREVADRVVFM 209
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
2-96 3.17e-19

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 79.20  E-value: 3.17e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTgnklRQDLIELWEERVINTRSMLLVTH 81
Cdd:NF040873  102 DALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTGLDAES----RERIIALLAEEHARGATVVVVTH 177

                          90
                  ....*....|....*
gi 1462843241  82 SvEEAVMLSDRVCLL 96
Cdd:NF040873  178 D-LELVRRADPCVLL 191
ABC_ThiQ_thiamine_transporter cd03298
ATP-binding cassette domain of the thiamine transport system; Part of the ...
 7-96 4.32e-19

ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213265 [Multi-domain]  Cd Length: 211  Bit Score: 79.07  E-value: 4.32e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   7 IGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVIntrSMLLVTHSVEEA 86
Cdd:cd03298   116 VGLAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAALDPALRAEMLDLVLDLHAETKM---TVLMVTHQPEDA 192

                          90
                  ....*....|
gi 1462843241  87 VMLSDRVCLL 96
Cdd:cd03298   193 KRLAQRVVFL 202
DppF COG1124
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 2-96 5.09e-19

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440741 [Multi-domain]  Cd Length: 248  Bit Score: 79.85  E-value: 5.09e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGLT-GYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTgnklrQDLI-----ELWEERVIntrS 75
Cdd:COG1124   120 ELLEQVGLPpSFLDRYPHQLSGGQRQRVAIARALILEPELLLLDEPTSALDVSV-----QAEIlnllkDLREERGL---T 191

                          90       100
                  ....*....|....*....|.
gi 1462843241  76 MLLVTHSVEEAVMLSDRVCLL 96
Cdd:COG1124   192 YLFVSHDLAVVAHLCDRVAVM 212
YnjD COG4136
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ...
 1-86 6.25e-19

ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];


Pssm-ID: 443311 [Multi-domain]  Cd Length: 211  Bit Score: 78.68  E-value: 6.25e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   1 MDMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDiftgNKLRQDLIELWEERVINTR-SMLLV 79
Cdd:COG4136   115 EQALEEAGLAGFADRDPATLSGGQRARVALLRALLAEPRALLLDEPFSKLD----AALRAQFREFVFEQIRQRGiPALLV 190


                  ....*..
gi 1462843241  80 THSVEEA 86
Cdd:COG4136   191 THDEEDA 197
FepC COG1120
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...
 1-113 6.71e-19

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];


Pssm-ID: 440737 [Multi-domain]  Cd Length: 254  Bit Score: 79.32  E-value: 6.71e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   1 MDMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIftGNKLR-QDLI-ELWEERvinTRSMLL 78
Cdd:COG1120   119 EEALERTGLEHLADRPVDELSGGERQRVLIARALAQEPPLLLLDEPTSHLDL--AHQLEvLELLrRLARER---GRTVVM 193

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1462843241  79 VTHSVEEAVMLSDRVCLL--GGL-----------PSTITDTFDIDIKR 113
Cdd:COG1120   194 VLHDLNLAARYADRLVLLkdGRIvaqgppeevltPELLEEVYGVEARV 241
modC PRK11144
molybdenum ABC transporter ATP-binding protein ModC;
5-96 1.10e-18

molybdenum ABC transporter ATP-binding protein ModC;


Pssm-ID: 182993 [Multi-domain]  Cd Length: 352  Bit Score: 80.30  E-value: 1.10e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   5 DLIGLTGYE---KAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEErvINTrSMLLVTH 81
Cdd:PRK11144  111 KIVALLGIEpllDRYPGSLSGGEKQRVAIGRALLTAPELLLMDEPLASLDLPRKRELLPYLERLARE--INI-PILYVSH 187

                          90
                  ....*....|....*
gi 1462843241  82 SVEEAVMLSDRVCLL 96
Cdd:PRK11144  188 SLDEILRLADRVVVL 202
glnQ PRK09493
glutamine ABC transporter ATP-binding protein GlnQ;
1-86 1.10e-18

glutamine ABC transporter ATP-binding protein GlnQ;


Pssm-ID: 181906 [Multi-domain]  Cd Length: 240  Bit Score: 78.60  E-value: 1.10e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   1 MDMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDiftgNKLRQDLIELWEERVINTRSMLLVT 80
Cdd:PRK09493  118 RELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKPKLMLFDEPTSALD----PELRHEVLKVMQDLAEEGMTMVIVT 193


                  ....*.
gi 1462843241  81 HSVEEA 86
Cdd:PRK09493  194 HEIGFA 199
FtsE COG2884
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
1-81 1.79e-18

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442130 [Multi-domain]  Cd Length: 223  Bit Score: 77.79  E-value: 1.79e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   1 MDMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPfsaldifTGN---KLRQDLIELWEErvINTR--S 75
Cdd:COG2884   119 REVLDLVGLSDKAKALPHELSGGEQQRVAIARALVNRPELLLADEP-------TGNldpETSWEIMELLEE--INRRgtT 189


                  ....*.
gi 1462843241  76 MLLVTH 81
Cdd:COG2884   190 VLIATH 195
ABC_MalK_N cd03301
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...
 5-96 2.96e-18

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.


Pssm-ID: 213268 [Multi-domain]  Cd Length: 213  Bit Score: 76.91  E-value: 2.96e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   5 DLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVINTrsmLLVTHSVE 84
Cdd:cd03301   116 ELLQIEHLLDRKPKQLSGGQRQRVALGRAIVREPKVFLMDEPLSNLDAKLRVQMRAELKRLQQRLGTTT---IYVTHDQV 192

                          90
                  ....*....|..
gi 1462843241  85 EAVMLSDRVCLL 96
Cdd:cd03301   193 EAMTMADRIAVM 204
ABC_Iron-Siderophores_B12_Hemin cd03214
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...
 4-98 3.85e-18

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.


Pssm-ID: 213181 [Multi-domain]  Cd Length: 180  Bit Score: 75.93  E-value: 3.85e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   4 LDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIftGNKLRqdLIELWEERVINT-RSMLLVTHS 82
Cdd:cd03214    82 LELLGLAHLADRPFNELSGGERQRVLLARALAQEPPILLLDEPTSHLDI--AHQIE--LLELLRRLARERgKTVVMVLHD 157

                          90
                  ....*....|....*.
gi 1462843241  83 VEEAVMLSDRVCLLGG 98
Cdd:cd03214   158 LNLAARYADRVILLKD 173
thiQ PRK10771
thiamine ABC transporter ATP-binding protein ThiQ;
2-92 9.56e-18

thiamine ABC transporter ATP-binding protein ThiQ;


Pssm-ID: 182716 [Multi-domain]  Cd Length: 232  Bit Score: 76.16  E-value: 9.56e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDiftgNKLRQDLIELWEErVINTR--SMLLV 79
Cdd:PRK10771  112 AIARQMGIEDLLARLPGQLSGGQRQRVALARCLVREQPILLLDEPFSALD----PALRQEMLTLVSQ-VCQERqlTLLMV 186

                          90
                  ....*....|...
gi 1462843241  80 THSVEEAVMLSDR 92
Cdd:PRK10771  187 SHSLEDAARIAPR 199
modC_ABC TIGR02142
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ...
 3-96 9.75e-18

molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]


Pssm-ID: 131197 [Multi-domain]  Cd Length: 354  Bit Score: 77.46  E-value: 9.75e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   3 MLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIftgnKLRQDLIELWEERVINTR-SMLLVTH 81
Cdd:TIGR02142 115 VIELLGIGHLLGRLPGRLSGGEKQRVAIGRALLSSPRLLLMDEPLAALDD----PRKYEILPYLERLHAEFGiPILYVSH 190

                          90
                  ....*....|....*
gi 1462843241  82 SVEEAVMLSDRVCLL 96
Cdd:TIGR02142 191 SLQEVLRLADRVVVL 205
AppF COG4608
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ...
 2-51 2.53e-17

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443658 [Multi-domain]  Cd Length: 329  Bit Score: 76.31  E-value: 2.53e-17
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1462843241   2 DMLDLIGL-TGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALD 51
Cdd:COG4608   139 ELLELVGLrPEHADRYPHEFSGGQRQRIGIARALALNPKLIVCDEPVSALD 189
potG PRK11607
putrescine ABC transporter ATP-binding subunit PotG;
2-96 4.53e-17

putrescine ABC transporter ATP-binding subunit PotG;


Pssm-ID: 183226 [Multi-domain]  Cd Length: 377  Bit Score: 76.03  E-value: 4.53e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWeERVINTRSMllVTH 81
Cdd:PRK11607  132 EMLGLVHMQEFAKRKPHQLSGGQRQRVALARSLAKRPKLLLLDEPMGALDKKLRDRMQLEVVDIL-ERVGVTCVM--VTH 208

                          90
                  ....*....|....*
gi 1462843241  82 SVEEAVMLSDRVCLL 96
Cdd:PRK11607  209 DQEEAMTMAGRIAIM 223
ABC_subfamily_A cd03263
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...
 3-96 8.44e-17

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.


Pssm-ID: 213230 [Multi-domain]  Cd Length: 220  Bit Score: 73.31  E-value: 8.44e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   3 MLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNklrqdliELWE--ERVINTRSMLLVT 80
Cdd:cd03263   117 LLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPSVLLLDEPTSGLDPASRR-------AIWDliLEVRKGRSIILTT 189

                          90
                  ....*....|....*.
gi 1462843241  81 HSVEEAVMLSDRVCLL 96
Cdd:cd03263   190 HSMDEAEALCDRIAIM 205
ABC_drug_resistance_like cd03264
ABC-type multidrug transport system, ATPase component; The biological function of this family ...
 3-96 1.01e-16

ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213231 [Multi-domain]  Cd Length: 211  Bit Score: 73.00  E-value: 1.01e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   3 MLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVIntrsmLLVTHS 82
Cdd:cd03264   114 VLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPSILIVDEPTAGLDPEERIRFRNLLSELGEDRIV-----ILSTHI 188

                          90
                  ....*....|....
gi 1462843241  83 VEEAVMLSDRVCLL 96
Cdd:cd03264   189 VEDVESLCNQVAVL 202
ABC_Mj1267_LivG_branched cd03219
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...
 1-93 2.17e-16

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).


Pssm-ID: 213186 [Multi-domain]  Cd Length: 236  Bit Score: 72.47  E-value: 2.17e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   1 MDMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIftgnKLRQDLIELWEERVINTRSMLLVT 80
Cdd:cd03219   125 EELLERVGLADLADRPAGELSYGQQRRLEIARALATDPKLLLLDEPAAGLNP----EETEELAELIRELRERGITVLLVE 200

                          90
                  ....*....|....
gi 1462843241  81 HSVeEAVM-LSDRV 93
Cdd:cd03219   201 HDM-DVVMsLADRV 213
PhnC COG3638
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ...
 1-93 3.26e-16

ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 442855 [Multi-domain]  Cd Length: 249  Bit Score: 72.40  E-value: 3.26e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   1 MDMLDLIGLTgyEKAYPR--ELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVIntrSMLL 78
Cdd:COG3638   128 LEALERVGLA--DKAYQRadQLSGGQQQRVAIARALVQEPKLILADEPVASLDPKTARQVMDLLRRIAREDGI---TVVV 202

                          90
                  ....*....|....*
gi 1462843241  79 VTHSVEEAVMLSDRV 93
Cdd:COG3638   203 NLHQVDLARRYADRI 217
PstB COG1117
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 19-93 4.33e-16

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440734 [Multi-domain]  Cd Length: 258  Bit Score: 71.99  E-value: 4.33e-16
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1462843241  19 ELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLrQDLI-ELWEERVIntrsmLLVTHSVEEAVMLSDRV 93
Cdd:COG1117   154 GLSGGQQQRLCIARALAVEPEVLLMDEPTSALDPISTAKI-EELIlELKKDYTI-----VIVTHNMQQAARVSDYT 223
LivG COG0411
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ...
 1-96 4.54e-16

ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];


Pssm-ID: 440180 [Multi-domain]  Cd Length: 257  Bit Score: 71.99  E-value: 4.54e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   1 MDMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALdiftGNKLRQDLIE----LWEERVIntrSM 76
Cdd:COG0411   134 EELLERVGLADRADEPAGNLSYGQQRRLEIARALATEPKLLLLDEPAAGL----NPEETEELAElirrLRDERGI---TI 206

                          90       100
                  ....*....|....*....|.
gi 1462843241  77 LLVTHSVeEAVM-LSDRVCLL 96
Cdd:COG0411   207 LLIEHDM-DLVMgLADRIVVL 226
CcmA COG4133
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ...
 2-51 5.33e-16

ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443308 [Multi-domain]  Cd Length: 206  Bit Score: 70.97  E-value: 5.33e-16
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALD 51
Cdd:COG4133   114 EALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSPAPLWLLDEPFTALD 163
thiQ TIGR01277
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ...
 7-96 5.71e-16

thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]


Pssm-ID: 130344 [Multi-domain]  Cd Length: 213  Bit Score: 71.05  E-value: 5.71e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   7 IGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDiftgNKLRQDLI----ELWEERvinTRSMLLVTHS 82
Cdd:TIGR01277 116 VGIADYLDRLPEQLSGGQRQRVALARCLVRPNPILLLDEPFSALD----PLLREEMLalvkQLCSER---QRTLLMVTHH 188

                          90
                  ....*....|....
gi 1462843241  83 VEEAVMLSDRVCLL 96
Cdd:TIGR01277 189 LSDARAIASQIAVV 202
FetA COG4619
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
18-96 5.78e-16

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443661 [Multi-domain]  Cd Length: 209  Bit Score: 71.00  E-value: 5.78e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  18 RELSGGMRQRVGFARALAVEPDLLLMDEPFSALDifTGNKLR-QDLIELWEERviNTRSMLLVTHSVEEAVMLSDRVCLL 96
Cdd:COG4619   129 ERLSGGERQRLALIRALLLQPDVLLLDEPTSALD--PENTRRvEELLREYLAE--EGRAVLWVSHDPEQIERVADRVLTL 204
PRK14239 PRK14239
phosphate transporter ATP-binding protein; Provisional
 20-92 6.65e-16

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184585 [Multi-domain]  Cd Length: 252  Bit Score: 71.35  E-value: 6.65e-16
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1462843241  20 LSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEErvintRSMLLVTHSVEEAVMLSDR 92
Cdd:PRK14239  149 LSGGQQQRVCIARVLATSPKIILLDEPTSALDPISAGKIEETLLGLKDD-----YTMLLVTRSMQQASRISDR 216
PRK10619 PRK10619
histidine ABC transporter ATP-binding protein HisP;
4-96 6.86e-16

histidine ABC transporter ATP-binding protein HisP;


Pssm-ID: 182592 [Multi-domain]  Cd Length: 257  Bit Score: 71.54  E-value: 6.86e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   4 LDLIGLTGYEKA-YPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDI-FTGNKLR--QDLIElweerviNTRSMLLV 79
Cdd:PRK10619  136 LAKVGIDERAQGkYPVHLSGGQQQRVSIARALAMEPEVLLFDEPTSALDPeLVGEVLRimQQLAE-------EGKTMVVV 208

                          90
                  ....*....|....*..
gi 1462843241  80 THSVEEAVMLSDRVCLL 96
Cdd:PRK10619  209 THEMGFARHVSSHVIFL 225
PRK14267 PRK14267
phosphate ABC transporter ATP-binding protein; Provisional
 14-96 7.06e-16

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184596 [Multi-domain]  Cd Length: 253  Bit Score: 71.41  E-value: 7.06e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  14 KAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVIntrsmLLVTHSVEEAVMLSDRV 93
Cdd:PRK14267  144 NDYPSNLSGGQRQRLVIARALAMKPKILLMDEPTANIDPVGTAKIEELLFELKKEYTI-----VLVTHSPAQAARVSDYV 218


                  ...
gi 1462843241  94 CLL 96
Cdd:PRK14267  219 AFL 221
metN PRK11153
DL-methionine transporter ATP-binding subunit; Provisional
 4-98 8.06e-16

DL-methionine transporter ATP-binding subunit; Provisional


Pssm-ID: 236863 [Multi-domain]  Cd Length: 343  Bit Score: 72.14  E-value: 8.06e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   4 LDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTgnklRQDLIELWEErvINTR---SMLLVT 80
Cdd:PRK11153  125 LELVGLSDKADRYPAQLSGGQKQRVAIARALASNPKVLLCDEATSALDPAT----TRSILELLKD--INRElglTIVLIT 198

                          90
                  ....*....|....*...
gi 1462843241  81 HSVEEAVMLSDRVCLLGG 98
Cdd:PRK11153  199 HEMDVVKRICDRVAVIDA 216
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
1-96 1.28e-15

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 71.90  E-value: 1.28e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   1 MDMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIftgnKLRQDL-IELWE-ERVINTrSMLL 78
Cdd:PRK09452  126 MEALRMVQLEEFAQRKPHQLSGGQQQRVAIARAVVNKPKVLLLDESLSALDY----KLRKQMqNELKAlQRKLGI-TFVF 200

                          90
                  ....*....|....*...
gi 1462843241  79 VTHSVEEAVMLSDRVCLL 96
Cdd:PRK09452  201 VTHDQEEALTMSDRIVVM 218
fbpC PRK11432
ferric ABC transporter ATP-binding protein;
4-93 1.81e-15

ferric ABC transporter ATP-binding protein;


Pssm-ID: 183133 [Multi-domain]  Cd Length: 351  Bit Score: 71.29  E-value: 1.81e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   4 LDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVINTrsmLLVTHSV 83
Cdd:PRK11432  121 LELVDLAGFEDRYVDQISGGQQQRVALARALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITS---LYVTHDQ 197

                          90
                  ....*....|
gi 1462843241  84 EEAVMLSDRV 93
Cdd:PRK11432  198 SEAFAVSDTV 207
YbbA COG4181
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ...
 2-86 1.81e-15

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443338 [Multi-domain]  Cd Length: 233  Bit Score: 70.16  E-value: 1.81e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERviNTrSMLLVTH 81
Cdd:COG4181   129 ALLERVGLGHRLDHYPAQLSGGEQQRVALARAFATEPAILFADEPTGNLDAATGEQIIDLLFELNRER--GT-TLVLVTH 205


                  ....*
gi 1462843241  82 SVEEA 86
Cdd:COG4181   206 DPALA 210
ModF COG1119
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ...
 1-112 2.00e-15

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];


Pssm-ID: 440736 [Multi-domain]  Cd Length: 250  Bit Score: 70.11  E-value: 2.00e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   1 MDMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERvinTRSMLLVT 80
Cdd:COG1119   124 RELLELLGLAHLADRPFGTLSQGEQRRVLIARALVKDPELLILDEPTAGLDLGARELLLALLDKLAAEG---APTLVLVT 200

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1462843241  81 HSVEE-------AVMLSD-RVCLLGGLPSTITD-----TFDIDIK 112
Cdd:COG1119   201 HHVEEippgithVLLLKDgRVVAAGPKEEVLTSenlseAFGLPVE 245
ABC_phnC TIGR02315
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ...
 1-105 2.33e-15

phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]


Pssm-ID: 131368 [Multi-domain]  Cd Length: 243  Bit Score: 70.02  E-value: 2.33e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   1 MDMLDLIGLTgyEKAYPR--ELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVIntrSMLL 78
Cdd:TIGR02315 127 LSALERVGLA--DKAYQRadQLSGGQQQRVAIARALAQQPDLILADEPIASLDPKTSKQVMDYLKRINKEDGI---TVII 201

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1462843241  79 VTHSVEEAVMLSDRVCLLG-------GLPSTITD 105
Cdd:TIGR02315 202 NLHQVDLAKKYADRIVGLKageivfdGAPSELDD 235
ABC_PhnC_transporter cd03256
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ...
 4-93 2.43e-15

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213223 [Multi-domain]  Cd Length: 241  Bit Score: 69.90  E-value: 2.43e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   4 LDLIGLTgyEKAYPR--ELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVIntrSMLLVTH 81
Cdd:cd03256   129 LERVGLL--DKAYQRadQLSGGQQQRVAIARALMQQPKLILADEPVASLDPASSRQVMDLLKRINREEGI---TVIVSLH 203

                          90
                  ....*....|..
gi 1462843241  82 SVEEAVMLSDRV 93
Cdd:cd03256   204 QVDLAREYADRI 215
ABCC_MRP_Like cd03228
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ...
 20-96 4.07e-15

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213195 [Multi-domain]  Cd Length: 171  Bit Score: 67.79  E-value: 4.07e-15
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1462843241  20 LSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLielweERVINTRSMLLVTHSVeEAVMLSDRVCLL 96
Cdd:cd03228    97 LSGGQRQRIAIARALLRDPPILILDEATSALDPETEALILEAL-----RALAKGKTVIVIAHRL-STIRDADRIIVL 167
YhaQ COG4152
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 1-96 6.09e-15

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443322 [Multi-domain]  Cd Length: 298  Bit Score: 69.37  E-value: 6.09e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   1 MDMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEerviNTRSMLLVT 80
Cdd:COG4152   111 DEWLERLGLGDRANKKVEELSKGNQQKVQLIAALLHDPELLILDEPFSGLDPVNVELLKDVIRELAA----KGTTVIFSS 186

                          90
                  ....*....|....*....
gi 1462843241  81 H---SVEEavmLSDRVCLL 96
Cdd:COG4152   187 HqmeLVEE---LCDRIVII 202
ABC_putative_ATPase cd03269
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...
 2-96 8.02e-15

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213236 [Multi-domain]  Cd Length: 210  Bit Score: 68.08  E-value: 8.02e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEerviNTRSMLLVTH 81
Cdd:cd03269   111 EWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPELLILDEPFSGLDPVNVELLKDVIRELAR----AGKTVILSTH 186

                          90
                  ....*....|....*
gi 1462843241  82 SVEEAVMLSDRVCLL 96
Cdd:cd03269   187 QMELVEELCDRVLLL 201
ECF_ATPase_1 TIGR04520
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
 4-96 8.11e-15

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275313 [Multi-domain]  Cd Length: 268  Bit Score: 68.61  E-value: 8.11e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   4 LDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDiftgNKLRQDLIE----LWEERVIntrSMLLV 79
Cdd:TIGR04520 121 LKLVGMEDFRDREPHLLSGGQKQRVAIAGVLAMRPDIIILDEATSMLD----PKGRKEVLEtirkLNKEEGI---TVISI 193

                          90
                  ....*....|....*..
gi 1462843241  80 THSVEEAVMlSDRVCLL 96
Cdd:TIGR04520 194 THDMEEAVL-ADRVIVM 209
LolD_lipo_ex TIGR02211
lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ...
 1-86 8.55e-15

lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ABC transporter family (pfam00005). LolD is involved in localization of lipoproteins in some bacteria. It works with a transmembrane protein LolC, which in some species is a paralogous pair LolC and LolE. Depending on whether the residue immediately following the new, modified N-terminal Cys residue, the nascent lipoprotein may be carried further by LolA and LolB to the outer membrane, or remain at the inner membrane. The top scoring proteins excluded by this model include homologs from the archaeal genus Methanosarcina. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 131266 [Multi-domain]  Cd Length: 221  Bit Score: 68.15  E-value: 8.55e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   1 MDMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELweERVINTrSMLLVT 80
Cdd:TIGR02211 123 YEMLEKVGLEHRINHRPSELSGGERQRVAIARALVNQPSLVLADEPTGNLDNNNAKIIFDLMLEL--NRELNT-SFLVVT 199


                  ....*.
gi 1462843241  81 HSVEEA 86
Cdd:TIGR02211 200 HDLELA 205
drrA TIGR01188
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin ...
 2-138 2.20e-14

daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other]


Pssm-ID: 130256 [Multi-domain]  Cd Length: 302  Bit Score: 67.80  E-value: 2.20e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVintrSMLLVTH 81
Cdd:TIGR01188 107 ELLELFELGEAADRPVGTYSGGMRRRLDIAASLIHQPDVLFLDEPTTGLDPRTRRAIWDYIRALKEEGV----TILLTTH 182

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1462843241  82 SVEEAVMLSDRVCLL-----------GGLPSTIT-DTFDIDIKRNQRTKESISSLVEKISTTLNERIAA 138
Cdd:TIGR01188 183 YMEEADKLCDRIAIIdhgriiaegtpEELKRRLGkDTLESRPRDIQSLKVEVSMLIAELGETGLGLLAV 251
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 2-94 2.29e-14

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 68.56  E-value: 2.29e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGLTGYE---KAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTgnklrQ----DLI-ELWEERVInt 73
Cdd:COG4172   136 ELLERVGIPDPErrlDAYPHQLSGGQRQRVMIAMALANEPDLLIADEPTTALDVTV-----QaqilDLLkDLQRELGM-- 208

                          90       100
                  ....*....|....*....|....
gi 1462843241  74 rSMLLVTHS---VEEavmLSDRVC 94
Cdd:COG4172   209 -ALLLITHDlgvVRR---FADRVA 228
ABCC_MRP_domain1 cd03250
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ...
 20-96 3.61e-14

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213217 [Multi-domain]  Cd Length: 204  Bit Score: 65.95  E-value: 3.61e-14
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1462843241  20 LSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLI--ELWEERvinTRsmLLVTHSVeEAVMLSDRVCLL 96
Cdd:cd03250   128 LSGGQKQRISLARAVYSDADIYLLDDPLSAVDAHVGRHIFENCIlgLLLNNK---TR--ILVTHQL-QLLPHADQIVVL 200
artP PRK11124
arginine transporter ATP-binding subunit; Provisional
 1-93 4.85e-14

arginine transporter ATP-binding subunit; Provisional


Pssm-ID: 182980 [Multi-domain]  Cd Length: 242  Bit Score: 66.19  E-value: 4.85e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   1 MDMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVintrSMLLVT 80
Cdd:PRK11124  123 EKLLERLRLKPYADRFPLHLSGGQQQRVAIARALMMEPQVLLFDEPTAALDPEITAQIVSIIRELAETGI----TQVIVT 198

                          90
                  ....*....|...
gi 1462843241  81 HSVEEAVMLSDRV 93
Cdd:PRK11124  199 HEVEVARKTASRV 211
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 16-51 6.01e-14

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 67.40  E-value: 6.01e-14
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1462843241  16 YPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALD 51
Cdd:COG4172   422 YPHEFSGGQRQRIAIARALILEPKLLVLDEPTSALD 457
ugpC PRK11650
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
17-93 8.08e-14

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;


Pssm-ID: 236947 [Multi-domain]  Cd Length: 356  Bit Score: 66.79  E-value: 8.08e-14
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1462843241  17 PRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIftgnKLR-QDLIELWE-ERVINTRSmLLVTHSVEEAVMLSDRV 93
Cdd:PRK11650  132 PRELSGGQRQRVAMGRAIVREPAVFLFDEPLSNLDA----KLRvQMRLEIQRlHRRLKTTS-LYVTHDQVEAMTLADRV 205
ABC_DrrA cd03265
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...
 2-96 9.96e-14

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213232 [Multi-domain]  Cd Length: 220  Bit Score: 65.08  E-value: 9.96e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEErviNTRSMLLVTH 81
Cdd:cd03265   114 ELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPEVLFLDEPTIGLDPQTRAHVWEYIEKLKEE---FGMTILLTTH 190

                          90
                  ....*....|....*
gi 1462843241  82 SVEEAVMLSDRVCLL 96
Cdd:cd03265   191 YMEEAEQLCDRVAII 205
ArtP COG4161
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
1-96 1.34e-13

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443326 [Multi-domain]  Cd Length: 242  Bit Score: 65.03  E-value: 1.34e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   1 MDMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVintrSMLLVT 80
Cdd:COG4161   123 MKLLARLRLTDKADRFPLHLSGGQQQRVAIARALMMEPQVLLFDEPTAALDPEITAQVVEIIRELSQTGI----TQVIVT 198

                          90
                  ....*....|....*.
gi 1462843241  81 HSVEEAVMLSDRVCLL 96
Cdd:COG4161   199 HEVEFARKVASQVVYM 214
PRK11000 PRK11000
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
17-98 1.40e-13

maltose/maltodextrin ABC transporter ATP-binding protein MalK;


Pssm-ID: 182893 [Multi-domain]  Cd Length: 369  Bit Score: 66.21  E-value: 1.40e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  17 PRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELwEERVinTRSMLLVTHSVEEAVMLSDRVCLL 96
Cdd:PRK11000  131 PKALSGGQRQRVAIGRTLVAEPSVFLLDEPLSNLDAALRVQMRIEISRL-HKRL--GRTMIYVTHDQVEAMTLADKIVVL 207


                  ..
gi 1462843241  97 GG 98
Cdd:PRK11000  208 DA 209
PRK14243 PRK14243
phosphate transporter ATP-binding protein; Provisional
 20-91 1.85e-13

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184588 [Multi-domain]  Cd Length: 264  Bit Score: 65.19  E-value: 1.85e-13
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1462843241  20 LSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVIntrsmLLVTHSVEEAVMLSD 91
Cdd:PRK14243  152 LSGGQQQRLCIARAIAVQPEVILMDEPCSALDPISTLRIEELMHELKEQYTI-----IIVTHNMQQAARVSD 218
CydC COG4987
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ...
 18-97 1.91e-13

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444011 [Multi-domain]  Cd Length: 569  Bit Score: 65.94  E-value: 1.91e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  18 RELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEErvintRSMLLVTH--SVEEAVmlsDRVCL 95
Cdd:COG4987   470 RRLSGGERRRLALARALLRDAPILLLDEPTEGLDAATEQALLADLLEALAG-----RTVLLITHrlAGLERM---DRILV 541


                  ..
gi 1462843241  96 LG 97
Cdd:COG4987   542 LE 543
ABC_Carb_Monos_I cd03216
First domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 20-96 2.30e-13

First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213183 [Multi-domain]  Cd Length: 163  Bit Score: 63.22  E-value: 2.30e-13
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1462843241  20 LSGGMRQRVGFARALAVEPDLLLMDEPFSALDiftgNKLRQDLIELWEERVINTRSMLLVTHSVEEAVMLSDRVCLL 96
Cdd:cd03216    83 LSVGERQMVEIARALARNARLLILDEPTAALT----PAEVERLFKVIRRLRAQGVAVIFISHRLDEVFEIADRVTVL 155
cbiO PRK13640
energy-coupling factor transporter ATPase;
2-135 2.30e-13

energy-coupling factor transporter ATPase;


Pssm-ID: 184200 [Multi-domain]  Cd Length: 282  Bit Score: 64.82  E-value: 2.30e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEErviNTRSMLLVTH 81
Cdd:PRK13640  126 DVLADVGMLDYIDSEPANLSGGQKQRVAIAGILAVEPKIIILDESTSMLDPAGKEQILKLIRKLKKK---NNLTVISITH 202

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1462843241  82 SVEEAVMLSDRVCLLGGlpSTITDTFDIDIKRNQRTKESIS---SLVEKISTTLNER 135
Cdd:PRK13640  203 DIDEANMADQVLVLDDG--KLLAQGSPVEIFSKVEMLKEIGldiPFVYKLKNKLKEK 257
L_ocin_972_ABC TIGR03608
putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly ...
 4-93 3.85e-13

putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly wide distribution consists of a polypeptide related to the lactococcin 972 (see TIGR01653) and multiple-membrane-spanning putative immunity protein (see TIGR01654). This model represents a small clade within the ABC transporters that regularly are found adjacent to these bacteriocin system gene pairs and are likely serve as export proteins. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]


Pssm-ID: 188353 [Multi-domain]  Cd Length: 206  Bit Score: 63.40  E-value: 3.85e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   4 LDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDiftgNKLRQDLIELWEERVINTRSMLLVTHSV 83
Cdd:TIGR03608 119 LEKVGLNLKLKQKIYELSGGEQQRVALARAILKPPPLILADEPTGSLD----PKNRDEVLDLLLELNDEGKTIIIVTHDP 194

                          90
                  ....*....|
gi 1462843241  84 EEAVMlSDRV 93
Cdd:TIGR03608 195 EVAKQ-ADRV 203
PRK13537 PRK13537
nodulation factor ABC transporter ATP-binding protein NodI;
18-96 5.09e-13

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237420 [Multi-domain]  Cd Length: 306  Bit Score: 64.06  E-value: 5.09e-13
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1462843241  18 RELSGGMRQRVGFARALAVEPDLLLMDEPFSALDiftgNKLRQDLIELWEERVINTRSMLLVTHSVEEAVMLSDRVCLL 96
Cdd:PRK13537  137 GELSGGMKRRLTLARALVNDPDVLVLDEPTTGLD----PQARHLMWERLRSLLARGKTILLTTHFMEEAERLCDRLCVI 211
PRK14258 PRK14258
phosphate ABC transporter ATP-binding protein; Provisional
 19-125 7.81e-13

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184593 [Multi-domain]  Cd Length: 261  Bit Score: 63.52  E-value: 7.81e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  19 ELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLrQDLIElwEERVINTRSMLLVTHSVEEAVMLSDRVCLLGG 98
Cdd:PRK14258  150 DLSGGQQQRLCIARALAVKPKVLLMDEPCFGLDPIASMKV-ESLIQ--SLRLRSELTMVIVSHNLHQVSRLSDFTAFFKG 226

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1462843241  99 LPSTITDTFDIDIKR-------NQRTKESISSLV 125
Cdd:PRK14258  227 NENRIGQLVEFGLTKkifnsphDSRTREYVLSRL 260
cbiO PRK13639
cobalt transporter ATP-binding subunit; Provisional
 1-128 1.56e-12

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184199 [Multi-domain]  Cd Length: 275  Bit Score: 62.79  E-value: 1.56e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   1 MDMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVintrSMLLVT 80
Cdd:PRK13639  119 KEALKAVGMEGFENKPPHHLSGGQKKRVAIAGILAMKPEIIVLDEPTSGLDPMGASQIMKLLYDLNKEGI----TIIIST 194

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1462843241  81 HSVEEAVMLSDRVCLL-------GGLPSTITDtfDIDIKRNQRTK-ESISSLVEKI 128
Cdd:PRK13639  195 HDVDLVPVYADKVYVMsdgkiikEGTPKEVFS--DIETIRKANLRlPRVAHLIEIL 248
oppD PRK09473
oligopeptide transporter ATP-binding component; Provisional
 14-93 1.73e-12

oligopeptide transporter ATP-binding component; Provisional


Pssm-ID: 181888 [Multi-domain]  Cd Length: 330  Bit Score: 62.82  E-value: 1.73e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  14 KAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELweERVINTrSMLLVTHSVEEAVMLSDRV 93
Cdd:PRK09473  156 KMYPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNEL--KREFNT-AIIMITHDLGVVAGICDKV 232
SunT COG2274
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...
 20-96 1.77e-12

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];


Pssm-ID: 441875 [Multi-domain]  Cd Length: 711  Bit Score: 63.31  E-value: 1.77e-12
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1462843241  20 LSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLielweERVINTRSMLLVTHSvEEAVMLSDRVCLL 96
Cdd:COG2274   612 LSGGQRQRLAIARALLRNPRILILDEATSALDAETEAIILENL-----RRLLKGRTVIIIAHR-LSTIRLADRIIVL 682
lolD PRK11629
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
1-93 2.04e-12

lipoprotein-releasing ABC transporter ATP-binding protein LolD;


Pssm-ID: 183244 [Multi-domain]  Cd Length: 233  Bit Score: 61.76  E-value: 2.04e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   1 MDMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELweeRVINTRSMLLVT 80
Cdd:PRK11629  127 LEMLAAVGLEHRANHRPSELSGGERQRVAIARALVNNPRLVLADEPTGNLDARNADSIFQLLGEL---NRLQGTAFLVVT 203

                          90
                  ....*....|...
gi 1462843241  81 HSVEEAVMLSDRV 93
Cdd:PRK11629  204 HDLQLAKRMSRQL 216
ABC_FtsE cd03292
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...
 1-97 2.42e-12

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages


Pssm-ID: 213259 [Multi-domain]  Cd Length: 214  Bit Score: 61.27  E-value: 2.42e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   1 MDMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKlrqdLIELWEErvINTR--SMLL 78
Cdd:cd03292   118 PAALELVGLSHKHRALPAELSGGEQQRVAIARAIVNSPTILIADEPTGNLDPDTTWE----IMNLLKK--INKAgtTVVV 191

                          90
                  ....*....|....*....
gi 1462843241  79 VTHSVEEAVMLSDRVCLLG 97
Cdd:cd03292   192 ATHAKELVDTTRHRVIALE 210
PRK11831 PRK11831
phospholipid ABC transporter ATP-binding protein MlaF;
1-91 2.94e-12

phospholipid ABC transporter ATP-binding protein MlaF;


Pssm-ID: 236997 [Multi-domain]  Cd Length: 269  Bit Score: 61.70  E-value: 2.94e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   1 MDMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVIntrSMLLVT 80
Cdd:PRK11831  125 MMKLEAVGLRGAAKLMPSELSGGMARRAALARAIALEPDLIMFDEPFVGQDPITMGVLVKLISELNSALGV---TCVVVS 201

                          90
                  ....*....|.
gi 1462843241  81 HSVEEAVMLSD 91
Cdd:PRK11831  202 HDVPEVLSIAD 212
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
 14-93 3.15e-12

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 62.42  E-value: 3.15e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  14 KAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEErvINTrSMLLVTHSVEEAVMLSDRV 93
Cdd:PRK15134  151 TDYPHQLSGGERQRVMIAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQQE--LNM-GLLFITHNLSIVRKLADRV 227
PRK13536 PRK13536
nodulation factor ABC transporter ATP-binding protein NodI;
19-96 4.57e-12

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237419 [Multi-domain]  Cd Length: 340  Bit Score: 61.77  E-value: 4.57e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  19 ELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTgnklrQDLIelWEE-RVINTR--SMLLVTHSVEEAVMLSDRVCL 95
Cdd:PRK13536  172 DLSGGMKRRLTLARALINDPQLLILDEPTTGLDPHA-----RHLI--WERlRSLLARgkTILLTTHFMEEAERLCDRLCV 244


                  .
gi 1462843241  96 L 96
Cdd:PRK13536  245 L 245
CydD COG4988
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ...
 20-96 5.85e-12

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444012 [Multi-domain]  Cd Length: 563  Bit Score: 61.70  E-value: 5.85e-12
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1462843241  20 LSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEErvintRSMLLVTHSvEEAVMLSDRVCLL 96
Cdd:COG4988   474 LSGGQAQRLALARALLRDAPLLLLDEPTAHLDAETEAEILQALRRLAKG-----RTVILITHR-LALLAQADRILVL 544
PRK15079 PRK15079
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
 16-93 6.77e-12

oligopeptide ABC transporter ATP-binding protein OppF; Provisional


Pssm-ID: 185037 [Multi-domain]  Cd Length: 331  Bit Score: 61.26  E-value: 6.77e-12
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1462843241  16 YPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVIntrSMLLVTHSVEEAVMLSDRV 93
Cdd:PRK15079  158 YPHEFSGGQCQRIGIARALILEPKLIICDEPVSALDVSIQAQVVNLLQQLQREMGL---SLIFIAHDLAVVKHISDRV 232
dppF PRK11308
dipeptide transporter ATP-binding subunit; Provisional
 2-52 6.88e-12

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 236898 [Multi-domain]  Cd Length: 327  Bit Score: 61.13  E-value: 6.88e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1462843241   2 DMLDLIGL-TGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDI 52
Cdd:PRK11308  136 AMMAKVGLrPEHYDRYPHMFSGGQRQRIAIARALMLDPDVVVADEPVSALDV 187
ABC_BcrA_bacitracin_resist cd03268
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ...
 4-98 7.56e-12

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.


Pssm-ID: 213235 [Multi-domain]  Cd Length: 208  Bit Score: 59.92  E-value: 7.56e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   4 LDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEErvinTRSMLLVTHSV 83
Cdd:cd03268   111 LDVVGLKDSAKKKVKGFSLGMKQRLGIALALLGNPDLLILDEPTNGLDPDGIKELRELILSLRDQ----GITVLISSHLL 186

                          90
                  ....*....|....*
gi 1462843241  84 EEAVMLSDRVCLLGG 98
Cdd:cd03268   187 SEIQKVADRIGIINK 201
cbiO PRK13643
energy-coupling factor transporter ATPase;
2-108 1.05e-11

energy-coupling factor transporter ATPase;


Pssm-ID: 184203 [Multi-domain]  Cd Length: 288  Bit Score: 60.52  E-value: 1.05e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGLTG--YEKAyPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDiftgNKLRQDLIELWEERVINTRSMLLV 79
Cdd:PRK13643  126 EKLEMVGLADefWEKS-PFELSGGQMRRVAIAGILAMEPEVLVLDEPTAGLD----PKARIEMMQLFESIHQSGQTVVLV 200

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1462843241  80 THSVEEAVMLSDRVCLLG-------GLPSTITDTFD 108
Cdd:PRK13643  201 THLMDDVADYADYVYLLEkghiiscGTPSDVFQEVD 236
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 2-48 1.09e-11

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 58.43  E-value: 1.09e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1462843241   2 DMLDLIGLTGYEK----AYPRELSGGMRQRVGFARALAVEPDLLLMDEPFS 48
Cdd:pfam00005 100 EALEKLGLGDLADrpvgERPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
nickel_nikD TIGR02770
nickel import ATP-binding protein NikD; This family represents the NikD subunit of a ...
 14-96 1.16e-11

nickel import ATP-binding protein NikD; This family represents the NikD subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. NikD and NikE are homologous. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131817 [Multi-domain]  Cd Length: 230  Bit Score: 59.69  E-value: 1.16e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  14 KAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVIntrSMLLVTHSVEEAVMLSDRV 93
Cdd:TIGR02770 120 KKYPFQLSGGMLQRVMIALALLLEPPFLIADEPTTDLDVVNQARVLKLLRELRQLFGT---GILLITHDLGVVARIADEV 196


                  ...
gi 1462843241  94 CLL 96
Cdd:TIGR02770 197 AVM 199
PRK14271 PRK14271
phosphate ABC transporter ATP-binding protein; Provisional
 17-96 1.17e-11

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172759 [Multi-domain]  Cd Length: 276  Bit Score: 60.11  E-value: 1.17e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  17 PRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLrQDLIELWEERVintrSMLLVTHSVEEAVMLSDRVCLL 96
Cdd:PRK14271  161 PFRLSGGQQQLLCLARTLAVNPEVLLLDEPTSALDPTTTEKI-EEFIRSLADRL----TVIIVTHNLAQAARISDRAALF 235
ABCC_bacteriocin_exporters cd03245
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...
 18-93 1.28e-11

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.


Pssm-ID: 213212 [Multi-domain]  Cd Length: 220  Bit Score: 59.53  E-value: 1.28e-11
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1462843241  18 RELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLielweERVINTRSMLLVTHsveEAVMLS--DRV 93
Cdd:cd03245   139 RGLSGGQRQAVALARALLNDPPILLLDEPTSAMDMNSEERLKERL-----RQLLGDKTLIIITH---RPSLLDlvDRI 208
PRK14247 PRK14247
phosphate ABC transporter ATP-binding protein; Provisional
 19-96 1.29e-11

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172735 [Multi-domain]  Cd Length: 250  Bit Score: 59.93  E-value: 1.29e-11
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1462843241  19 ELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVIntrsmLLVTHSVEEAVMLSDRVCLL 96
Cdd:PRK14247  146 KLSGGQQQRLCIARALAFQPEVLLADEPTANLDPENTAKIESLFLELKKDMTI-----VLVTHFPQQAARISDYVAFL 218
cbiO PRK13634
cobalt transporter ATP-binding subunit; Provisional
 3-96 1.43e-11

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237454 [Multi-domain]  Cd Length: 290  Bit Score: 60.03  E-value: 1.43e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   3 MLDLIGLT-GYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDiftgNKLRQDLIELWE----ERVINTrsmL 77
Cdd:PRK13634  128 MIELVGLPeELLARSPFELSGGQMRRVAIAGVLAMEPEVLVLDEPTAGLD----PKGRKEMMEMFYklhkEKGLTT---V 200

                          90
                  ....*....|....*....
gi 1462843241  78 LVTHSVEEAVMLSDRVCLL 96
Cdd:PRK13634  201 LVTHSMEDAARYADQIVVM 219
PRK10908 PRK10908
cell division ATP-binding protein FtsE;
4-83 1.47e-11

cell division ATP-binding protein FtsE;


Pssm-ID: 182829 [Multi-domain]  Cd Length: 222  Bit Score: 59.50  E-value: 1.47e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   4 LDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDiftgNKLRQDLIELWEE--RVINTrsMLLVTH 81
Cdd:PRK10908  122 LDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKPAVLLADEPTGNLD----DALSEGILRLFEEfnRVGVT--VLMATH 195


                  ..
gi 1462843241  82 SV 83
Cdd:PRK10908  196 DI 197
ABC_cobalt_CbiO_domain2 cd03226
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ...
 4-98 1.57e-11

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213193 [Multi-domain]  Cd Length: 205  Bit Score: 59.19  E-value: 1.57e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   4 LDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDifTGNKlrQDLIELWEERVINTRSMLLVTHSV 83
Cdd:cd03226   111 LKDLDLYALKERHPLSLSGGQKQRLAIAAALLSGKDLLIFDEPTSGLD--YKNM--ERVGELIRELAAQGKAVIVITHDY 186

                          90
                  ....*....|....*
gi 1462843241  84 EEAVMLSDRVCLLGG 98
Cdd:cd03226   187 EFLAKVCDRVLLLAN 201
ABC_NatA_sodium_exporter cd03266
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...
 19-96 2.08e-11

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.


Pssm-ID: 213233 [Multi-domain]  Cd Length: 218  Bit Score: 58.92  E-value: 2.08e-11
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1462843241  19 ELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEErvinTRSMLLVTHSVEEAVMLSDRVCLL 96
Cdd:cd03266   136 GFSTGMRQKVAIARALVHDPPVLLLDEPTTGLDVMATRALREFIRQLRAL----GKCILFSTHIMQEVERLCDRVVVL 209
cbiO PRK13650
energy-coupling factor transporter ATPase;
4-104 2.09e-11

energy-coupling factor transporter ATPase;


Pssm-ID: 184209 [Multi-domain]  Cd Length: 279  Bit Score: 59.36  E-value: 2.09e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   4 LDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDiftgNKLRQDLIELWEE-RVINTRSMLLVTHS 82
Cdd:PRK13650  125 LELVGMQDFKEREPARLSGGQKQRVAIAGAVAMRPKIIILDEATSMLD----PEGRLELIKTIKGiRDDYQMTVISITHD 200

                          90       100
                  ....*....|....*....|....
gi 1462843241  83 VEEaVMLSDRVCLL--GGLPSTIT 104
Cdd:PRK13650  201 LDE-VALSDRVLVMknGQVESTST 223
cbiO PRK13632
cobalt transporter ATP-binding subunit; Provisional
 7-134 2.28e-11

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237452 [Multi-domain]  Cd Length: 271  Bit Score: 59.23  E-value: 2.28e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   7 IGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERvinTRSMLLVTHSVEEA 86
Cdd:PRK13632  130 VGMEDYLDKEPQNLSGGQKQRVAIASVLALNPEIIIFDESTSMLDPKGKREIKKIMVDLRKTR---KKTLISITHDMDEA 206

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1462843241  87 VmLSDRVCLLG-------GLPSTITDTFDI--DIKRNQRTKESISSLVEKISTTLNE 134
Cdd:PRK13632  207 I-LADKVIVFSegkliaqGKPKEILNNKEIleKAKIDSPFIYKLSKKLKGIDPTYNE 262
COG4559 COG4559
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
4-52 2.84e-11

ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443620 [Multi-domain]  Cd Length: 258  Bit Score: 58.97  E-value: 2.84e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1462843241   4 LDLIGLTGY-EKAYPrELSGGMRQRVGFARALA-------VEPDLLLMDEPFSALDI 52
Cdd:COG4559   118 LALVGLAHLaGRSYQ-TLSGGEQQRVQLARVLAqlwepvdGGPRWLFLDEPTSALDL 173
CydD TIGR02857
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ...
 17-96 3.17e-11

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD


Pssm-ID: 274323 [Multi-domain]  Cd Length: 529  Bit Score: 59.61  E-value: 3.17e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  17 PRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLielweERVINTRSMLLVTHSvEEAVMLSDRVCLL 96
Cdd:TIGR02857 456 GAGLSGGQAQRLALARAFLRDAPLLLLDEPTAHLDAETEAEVLEAL-----RALAQGRTVLLVTHR-LALAALADRIVVL 529
PRK14246 PRK14246
phosphate ABC transporter ATP-binding protein; Provisional
 19-96 3.17e-11

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172734 [Multi-domain]  Cd Length: 257  Bit Score: 58.91  E-value: 3.17e-11
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1462843241  19 ELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVIntrsmLLVTHSVEEAVMLSDRVCLL 96
Cdd:PRK14246  153 QLSGGQQQRLTIARALALKPKVLLMDEPTSMIDIVNSQAIEKLITELKNEIAI-----VIVSHNPQQVARVADYVAFL 225
ABC_KpsT_Wzt cd03220
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...
 18-96 3.35e-11

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.


Pssm-ID: 213187 [Multi-domain]  Cd Length: 224  Bit Score: 58.31  E-value: 3.35e-11
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1462843241  18 RELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEerviNTRSMLLVTHSVEEAVMLSDRVCLL 96
Cdd:cd03220   141 KTYSSGMKARLAFAIATALEPDILLIDEVLAVGDAAFQEKCQRRLRELLK----QGKTVILVSHDPSSIKRLCDRALVL 215
FtsE TIGR02673
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC ...
 2-97 5.49e-11

cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC transporter ATP-binding protein family. This protein, and its permease partner FtsX, localize to the division site. In a number of species, the ftsEX gene pair is located next to FtsY, the signal recognition particle-docking protein. [Cellular processes, Cell division]


Pssm-ID: 131721 [Multi-domain]  Cd Length: 214  Bit Score: 57.64  E-value: 5.49e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPfsaldifTGN---KLRQDLIELWEERVINTRSMLL 78
Cdd:TIGR02673 120 AALRQVGLEHKADAFPEQLSGGEQQRVAIARAIVNSPPLLLADEP-------TGNldpDLSERILDLLKRLNKRGTTVIV 192

                          90
                  ....*....|....*....
gi 1462843241  79 VTHSVEEAVMLSDRVCLLG 97
Cdd:TIGR02673 193 ATHDLSLVDRVAHRVIILD 211
TagH COG1134
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...
 21-96 7.56e-11

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440749 [Multi-domain]  Cd Length: 245  Bit Score: 57.78  E-value: 7.56e-11
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1462843241  21 SGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEErvinTRSMLLVTHSVEEAVMLSDRVCLL 96
Cdd:COG1134   148 SSGMRARLAFAVATAVDPDILLVDEVLAVGDAAFQKKCLARIRELRES----GRTVIFVSHSMGAVRRLCDRAIWL 219
dppD PRK11022
dipeptide transporter ATP-binding subunit; Provisional
 1-81 9.00e-11

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 182906 [Multi-domain]  Cd Length: 326  Bit Score: 57.83  E-value: 9.00e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   1 MDMLDLIGLTGYEK---AYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVIntrSML 77
Cdd:PRK11022  132 IDLLNQVGIPDPASrldVYPHQLSGGMSQRVMIAMAIACRPKLLIADEPTTALDVTIQAQIIELLLELQQKENM---ALV 208


                  ....
gi 1462843241  78 LVTH 81
Cdd:PRK11022  209 LITH 212
cbiO PRK13631
cobalt transporter ATP-binding subunit; Provisional
 17-96 9.14e-11

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237451 [Multi-domain]  Cd Length: 320  Bit Score: 57.94  E-value: 9.14e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  17 PRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDiftgNKLRQDLIELWEERVINTRSMLLVTHSVEEAVMLSDRVCLL 96
Cdd:PRK13631  174 PFGLSGGQKRRVAIAGILAIQPEILIFDEPTAGLD----PKGEHEMMQLILDAKANNKTVFVITHTMEHVLEVADEVIVM 249
LptB COG1137
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ...
 20-96 9.78e-11

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440752 [Multi-domain]  Cd Length: 240  Bit Score: 57.35  E-value: 9.78e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  20 LSGGMRQRVGFARALAVEPDLLLMDEPF------SALDIftgnklrQDLIELWEERVIntrSMLLVTHSVEEAVMLSDRV 93
Cdd:COG1137   137 LSGGERRRVEIARALATNPKFILLDEPFagvdpiAVADI-------QKIIRHLKERGI---GVLITDHNVRETLGICDRA 206


                  ...
gi 1462843241  94 CLL 96
Cdd:COG1137   207 YII 209
hmuV PRK13548
hemin importer ATP-binding subunit; Provisional
 2-52 1.31e-10

hemin importer ATP-binding subunit; Provisional


Pssm-ID: 237422 [Multi-domain]  Cd Length: 258  Bit Score: 57.09  E-value: 1.31e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1462843241   2 DMLDLIGLTGYEKAYPRELSGGMRQRVGFARALA------VEPDLLLMDEPFSALDI 52
Cdd:PRK13548  117 AALAQVDLAHLAGRDYPQLSGGEQQRVQLARVLAqlwepdGPPRWLLLDEPTSALDL 173
cbiO PRK13637
energy-coupling factor transporter ATPase;
4-103 1.38e-10

energy-coupling factor transporter ATPase;


Pssm-ID: 237455 [Multi-domain]  Cd Length: 287  Bit Score: 57.36  E-value: 1.38e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   4 LDLIGLT--GYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDiftgNKLRQDLIELWEE-RVINTRSMLLVT 80
Cdd:PRK13637  127 MNIVGLDyeDYKDKSPFELSGGQKRRVAIAGVVAMEPKILILDEPTAGLD----PKGRDEILNKIKElHKEYNMTIILVS 202

                          90       100       110
                  ....*....|....*....|....*....|
gi 1462843241  81 HSVEEAVMLSDRV-------CLLGGLPSTI 103
Cdd:PRK13637  203 HSMEDVAKLADRIivmnkgkCELQGTPREV 232
ABCC_SUR1_N cd03290
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ...
 20-84 1.40e-10

ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213257 [Multi-domain]  Cd Length: 218  Bit Score: 56.57  E-value: 1.40e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1462843241  20 LSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQD-LIELWEErviNTRSMLLVTHSVE 84
Cdd:cd03290   141 LSGGQRQRICVARALYQNTNIVFLDDPFSALDIHLSDHLMQEgILKFLQD---DKRTLVLVTHKLQ 203
btuD PRK09536
corrinoid ABC transporter ATPase; Reviewed
 19-108 1.67e-10

corrinoid ABC transporter ATPase; Reviewed


Pssm-ID: 236554 [Multi-domain]  Cd Length: 402  Bit Score: 57.54  E-value: 1.67e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  19 ELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIftgNKLRQDLiELWEERVINTRSMLLVTHSVEEAVMLSDRVCLL-- 96
Cdd:PRK09536  139 SLSGGERQRVLLARALAQATPVLLLDEPTASLDI---NHQVRTL-ELVRRLVDDGKTAVAAIHDLDLAARYCDELVLLad 214

                          90       100
                  ....*....|....*....|...
gi 1462843241  97 GGL-----------PSTITDTFD 108
Cdd:PRK09536  215 GRVraagppadvltADTLRAAFD 237
MdlB COG1132
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
20-96 1.80e-10

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];


Pssm-ID: 440747 [Multi-domain]  Cd Length: 579  Bit Score: 57.48  E-value: 1.80e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  20 LSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLielweERVINTRSMLLVTH---SVEEAvmlsDRVCLL 96
Cdd:COG1132   477 LSGGQRQRIAIARALLKDPPILILDEATSALDTETEALIQEAL-----ERLMKGRTTIVIAHrlsTIRNA----DRILVL 547
ABC_TM1139_LivF_branched cd03224
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...
 20-96 2.24e-10

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.


Pssm-ID: 213191 [Multi-domain]  Cd Length: 222  Bit Score: 56.29  E-value: 2.24e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  20 LSGGMRQRVGFARALAVEPDLLLMDEPFSAL------DIFtgnklrQDLIELWEERVintrSMLLVTHSVEEAVMLSDRV 93
Cdd:cd03224   133 LSGGEQQMLAIARALMSRPKLLLLDEPSEGLapkiveEIF------EAIRELRDEGV----TILLVEQNARFALEIADRA 202


                  ...
gi 1462843241  94 CLL 96
Cdd:cd03224   203 YVL 205
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
 1-107 2.54e-10

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 57.12  E-value: 2.54e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   1 MDMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVIntrSMLLVT 80
Cdd:TIGR03269 150 VDLIEMVQLSHRITHIARDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKASGI---SMVLTS 226

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1462843241  81 HSVEEAVMLSDRVCLLG-------GLPSTITDTF 107
Cdd:TIGR03269 227 HWPEVIEDLSDKAIWLEngeikeeGTPDEVVAVF 260
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
 16-51 2.86e-10

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 56.64  E-value: 2.86e-10
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1462843241  16 YPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALD 51
Cdd:PRK15134  422 YPAEFSGGQRQRIAIARALILKPSLIILDEPTSSLD 457
PRK13651 PRK13651
cobalt transporter ATP-binding subunit; Provisional
 2-93 3.46e-10

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184210 [Multi-domain]  Cd Length: 305  Bit Score: 56.25  E-value: 3.46e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGL-TGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIfTGNKlrqDLIELWEERVINTRSMLLVT 80
Cdd:PRK13651  147 KYIELVGLdESYLQRSPFELSGGQKRRVALAGILAMEPDFLVFDEPTAGLDP-QGVK---EILEIFDNLNKQGKTIILVT 222

                          90
                  ....*....|...
gi 1462843241  81 HSVEEAVMLSDRV 93
Cdd:PRK13651  223 HDLDNVLEWTKRT 235
PRK10584 PRK10584
putative ABC transporter ATP-binding protein YbbA; Provisional
 2-98 3.71e-10

putative ABC transporter ATP-binding protein YbbA; Provisional


Pssm-ID: 182569 [Multi-domain]  Cd Length: 228  Bit Score: 55.56  E-value: 3.71e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEErviNTRSMLLVTH 81
Cdd:PRK10584  129 ALLEQLGLGKRLDHLPAQLSGGEQQRVALARAFNGRPDVLFADEPTGNLDRQTGDKIADLLFSLNRE---HGTTLILVTH 205

                          90
                  ....*....|....*..
gi 1462843241  82 SVEEAVMLSDRVCLLGG 98
Cdd:PRK10584  206 DLQLAARCDRRLRLVNG 222
phnK PRK11701
phosphonate C-P lyase system protein PhnK; Provisional
 17-93 4.45e-10

phosphonate C-P lyase system protein PhnK; Provisional


Pssm-ID: 183280 [Multi-domain]  Cd Length: 258  Bit Score: 55.70  E-value: 4.45e-10
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1462843241  17 PRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVIntrSMLLVTHSVEEAVMLSDRV 93
Cdd:PRK11701  149 PTTFSGGMQQRLQIARNLVTHPRLVFMDEPTGGLDVSVQARLLDLLRGLVRELGL---AVVIVTHDLAVARLLAHRL 222
nikE PRK10419
nickel ABC transporter ATP-binding protein NikE;
3-113 4.90e-10

nickel ABC transporter ATP-binding protein NikE;


Pssm-ID: 236689 [Multi-domain]  Cd Length: 268  Bit Score: 55.46  E-value: 4.90e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   3 MLDLIGLT-GYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVIntrSMLLVTH 81
Cdd:PRK10419  134 MLRAVDLDdSVLDKRPPQLSGGQLQRVCLARALAVEPKLLILDEAVSNLDLVLQAGVIRLLKKLQQQFGT---ACLFITH 210

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1462843241  82 S---VE---EAVMLSDRVCLLGGLPSTITDTFDIDIKR 113
Cdd:PRK10419  211 DlrlVErfcQRVMVMDNGQIVETQPVGDKLTFSSPAGR 248
CydC TIGR02868
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ...
 20-82 5.83e-10

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.


Pssm-ID: 274331 [Multi-domain]  Cd Length: 530  Bit Score: 55.83  E-value: 5.83e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1462843241  20 LSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVIntrsmLLVTHS 82
Cdd:TIGR02868 472 LSGGERQRLALARALLADAPILLLDEPTEHLDAETADELLEDLLAALSGRTV-----VLITHH 529
cbiO PRK13645
energy-coupling factor transporter ATPase;
2-96 5.98e-10

energy-coupling factor transporter ATPase;


Pssm-ID: 184204 [Multi-domain]  Cd Length: 289  Bit Score: 55.40  E-value: 5.98e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGL-TGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDiftgNKLRQDLIELWEERVIN-TRSMLLV 79
Cdd:PRK13645  132 ELLKLVQLpEDYVKRSPFELSGGQKRRVALAGIIAMDGNTLVLDEPTGGLD----PKGEEDFINLFERLNKEyKKRIIMV 207

                          90
                  ....*....|....*..
gi 1462843241  80 THSVEEAVMLSDRVCLL 96
Cdd:PRK13645  208 THNMDQVLRIADEVIVM 224
ABCC_ATM1_transporter cd03253
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ...
 20-96 6.81e-10

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213220 [Multi-domain]  Cd Length: 236  Bit Score: 54.93  E-value: 6.81e-10
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1462843241  20 LSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLielweERVINTRSMLLVTHSVEEaVMLSDRVCLL 96
Cdd:cd03253   138 LSGGEKQRVAIARAILKNPPILLLDEATSALDTHTEREIQAAL-----RDVSKGRTTIVIAHRLST-IVNADKIIVL 208
cbiO PRK13635
energy-coupling factor ABC transporter ATP-binding protein;
2-96 8.06e-10

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184195 [Multi-domain]  Cd Length: 279  Bit Score: 55.02  E-value: 8.06e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDiftgNKLRQDLIELweERVINTRSMLLV-- 79
Cdd:PRK13635  123 QALRQVGMEDFLNREPHRLSGGQKQRVAIAGVLALQPDIIILDEATSMLD----PRGRREVLET--VRQLKEQKGITVls 196

                          90
                  ....*....|....*...
gi 1462843241  80 -THSVEEAVMlSDRVCLL 96
Cdd:PRK13635  197 iTHDLDEAAQ-ADRVIVM 213
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 18-81 8.45e-10

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 55.46  E-value: 8.45e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1462843241  18 RELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIftgnklrqDLIElWEERVINTR--SMLLVTH 81
Cdd:COG0488   151 SELSGGWRRRVALARALLSEPDLLLLDEPTNHLDL--------ESIE-WLEEFLKNYpgTVLVVSH 207
cbiO PRK13649
energy-coupling factor transporter ATPase;
4-103 8.59e-10

energy-coupling factor transporter ATPase;


Pssm-ID: 184208 [Multi-domain]  Cd Length: 280  Bit Score: 55.14  E-value: 8.59e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   4 LDLIGLTG--YEKAyPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDiftgNKLRQDLIELWEERVINTRSMLLVTH 81
Cdd:PRK13649  129 LALVGISEslFEKN-PFELSGGQMRRVAIAGILAMEPKILVLDEPTAGLD----PKGRKELMTLFKKLHQSGMTIVLVTH 203

                          90       100
                  ....*....|....*....|....*....
gi 1462843241  82 SVEEAVMLSDRV-------CLLGGLPSTI 103
Cdd:PRK13649  204 LMDDVANYADFVyvlekgkLVLSGKPKDI 232
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
 16-96 1.02e-09

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 55.25  E-value: 1.02e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  16 YPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQdLIELWEERVinTRSMLLVTHSVEEAVMLSDRVCL 95
Cdd:PRK10261  165 YPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQ-LIKVLQKEM--SMGVIFITHDMGVVAEIADRVLV 241


                  .
gi 1462843241  96 L 96
Cdd:PRK10261  242 M 242
ABC_NatA_like cd03267
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...
 18-97 1.79e-09

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.


Pssm-ID: 213234 [Multi-domain]  Cd Length: 236  Bit Score: 53.88  E-value: 1.79e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  18 RELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVIntrSMLLVTHSVEEAVMLSDRVCLLG 97
Cdd:cd03267   152 RQLSLGQRMRAEIAAALLHEPEILFLDEPTIGLDVVAQENIRNFLKEYNRERGT---TVLLTSHYMKDIEALARRVLVID 228
SapF COG4167
ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];
16-81 1.81e-09

ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];


Pssm-ID: 443328 [Multi-domain]  Cd Length: 265  Bit Score: 54.07  E-value: 1.81e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1462843241  16 YPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVIntrSMLLVTH 81
Cdd:COG4167   146 YPHMLSSGQKQRVALARALILQPKIIIADEALAALDMSVRSQIINLMLELQEKLGI---SYIYVSQ 208
PRK15056 PRK15056
manganese/iron ABC transporter ATP-binding protein;
19-106 1.81e-09

manganese/iron ABC transporter ATP-binding protein;


Pssm-ID: 185016 [Multi-domain]  Cd Length: 272  Bit Score: 54.12  E-value: 1.81e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  19 ELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEErvinTRSMLLVTHSVEEAVMLSDRVCLLGG 98
Cdd:PRK15056  142 ELSGGQKKRVFLARAIAQQGQVILLDEPFTGVDVKTEARIISLLRELRDE----GKTMLVSTHNLGSVTEFCDYTVMVKG 217

                          90
                  ....*....|
gi 1462843241  99 --LPSTITDT 106
Cdd:PRK15056  218 tvLASGPTET 227
CP_lyasePhnK TIGR02323
phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P ...
 17-93 1.90e-09

phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated complex. This protein (PhnK) and the adjacent-encoded PhnL resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this complex rather than part of a transporter per se. [Central intermediary metabolism, Phosphorus compounds]


Pssm-ID: 188208 [Multi-domain]  Cd Length: 253  Bit Score: 54.07  E-value: 1.90e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1462843241  17 PRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIftgnKLRQDLIELWEERVINTR-SMLLVTHSVEEAVMLSDRV 93
Cdd:TIGR02323 146 PRAFSGGMQQRLQIARNLVTRPRLVFMDEPTGGLDV----SVQARLLDLLRGLVRDLGlAVIIVTHDLGVARLLAQRL 219
PhnL COG4778
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ...
 15-93 2.02e-09

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];


Pssm-ID: 443809 [Multi-domain]  Cd Length: 229  Bit Score: 53.59  E-value: 2.02e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  15 AYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDiftgNKLRQDLIELWEERVINTRSMLLVTHsvEEAVM--LSDR 92
Cdd:COG4778   148 LPPATFSGGEQQRVNIARGFIADPPLLLLDEPTASLD----AANRAVVVELIEEAKARGTAIIGIFH--DEEVReaVADR 221


                  .
gi 1462843241  93 V 93
Cdd:COG4778   222 V 222
ABC_YhbG cd03218
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...
 2-96 2.14e-09

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.


Pssm-ID: 213185 [Multi-domain]  Cd Length: 232  Bit Score: 53.70  E-value: 2.14e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLrQDLIELWEERVIntrSMLLVTH 81
Cdd:cd03218   116 ELLEEFHITHLRKSKASSLSGGERRRVEIARALATNPKFLLLDEPFAGVDPIAVQDI-QKIIKILKDRGI---GVLITDH 191

                          90
                  ....*....|....*
gi 1462843241  82 SVEEAVMLSDRVCLL 96
Cdd:cd03218   192 NVRETLSITDRAYII 206
YddA COG4178
ABC-type uncharacterized transport system, permease and ATPase components [General function ...
 13-51 2.20e-09

ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];


Pssm-ID: 443337 [Multi-domain]  Cd Length: 571  Bit Score: 54.04  E-value: 2.20e-09
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1462843241  13 EKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALD 51
Cdd:COG4178   479 EADWDQVLSLGEQQRLAFARLLLHKPDWLFLDEATSALD 517
ABCC_TAP cd03248
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ...
 19-86 2.48e-09

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.


Pssm-ID: 213215 [Multi-domain]  Cd Length: 226  Bit Score: 53.24  E-value: 2.48e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1462843241  19 ELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIElWEERvintRSMLLVTH---SVEEA 86
Cdd:cd03248   150 QLSGGQKQRVAIARALIRNPQVLILDEATSALDAESEQQVQQALYD-WPER----RTVLVIAHrlsTVERA 215
ABC_RNaseL_inhibitor_domain1 cd03236
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 19-101 2.88e-09

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213203 [Multi-domain]  Cd Length: 255  Bit Score: 53.52  E-value: 2.88e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  19 ELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIftgnKLRQDLIELWEERVINTRSMLLVTHSVEEAVMLSDRVCLLGG 98
Cdd:cd03236   139 QLSGGELQRVAIAAALARDADFYFFDEPSSYLDI----KQRLNAARLIRELAEDDNYVLVVEHDLAVLDYLSDYIHCLYG 214


                  ...
gi 1462843241  99 LPS 101
Cdd:cd03236   215 EPG 217
cbiO PRK13648
cobalt transporter ATP-binding subunit; Provisional
 2-103 3.83e-09

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184207 [Multi-domain]  Cd Length: 269  Bit Score: 53.22  E-value: 3.83e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDligltgYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDiftgNKLRQDLIELWEE-RVINTRSMLLVT 80
Cdd:PRK13648  131 DMLE------RADYEPNALSGGQKQRVAIAGVLALNPSVIILDEATSMLD----PDARQNLLDLVRKvKSEHNITIISIT 200

                          90       100       110
                  ....*....|....*....|....*....|
gi 1462843241  81 HSVEEAvMLSDRVCLLG-------GLPSTI 103
Cdd:PRK13648  201 HDLSEA-MEADHVIVMNkgtvykeGTPTEI 229
ABC_RNaseL_inhibitor_domain2 cd03237
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 18-101 3.92e-09

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213204 [Multi-domain]  Cd Length: 246  Bit Score: 52.80  E-value: 3.92e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  18 RELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIftgnklrqdlielwEERVINTR-----------SMLLVTHSVEEA 86
Cdd:cd03237   114 PELSGGELQRVAIAACLSKDADIYLLDEPSAYLDV--------------EQRLMASKvirrfaennekTAFVVEHDIIMI 179

                          90
                  ....*....|....*
gi 1462843241  87 VMLSDRVCLLGGLPS 101
Cdd:cd03237   180 DYLADRLIVFEGEPS 194
ABC_Carb_Monos_II cd03215
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 17-94 4.21e-09

Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213182 [Multi-domain]  Cd Length: 182  Bit Score: 52.05  E-value: 4.21e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1462843241  17 PRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVintrSMLLVTHSVEEAVMLSDRVC 94
Cdd:cd03215   102 SSLLSGGNQQKVVLARWLARDPRVLILDEPTRGVDVGAKAEIYRLIRELADAGK----AVLLISSELDELLGLCDRIL 175
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
 16-96 6.13e-09

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 52.94  E-value: 6.13e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  16 YPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVIntrSMLLVTHSVEEAVMLSDRVCL 95
Cdd:PRK10261  460 YPHEFSGGQRQRICIARALALNPKVIIADEAVSALDVSIRGQIINLLLDLQRDFGI---AYLFISHDMAVVERISHRVAV 536


                  .
gi 1462843241  96 L 96
Cdd:PRK10261  537 M 537
ABCF_EF-3 cd03221
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ...
 15-81 6.33e-09

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.


Pssm-ID: 213188 [Multi-domain]  Cd Length: 144  Bit Score: 50.91  E-value: 6.33e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1462843241  15 AYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELweervinTRSMLLVTH 81
Cdd:cd03221    66 GYFEQLSGGEKMRLALAKLLLENPNLLLLDEPTNHLDLESIEALEEALKEY-------PGTVILVSH 125
ABCD_peroxisomal_ALDP cd03223
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ...
 15-60 6.54e-09

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).


Pssm-ID: 213190 [Multi-domain]  Cd Length: 166  Bit Score: 51.39  E-value: 6.54e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1462843241  15 AYP--RELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQ 60
Cdd:cd03223    85 IYPwdDVLSGGEQQRLAFARLLLHKPKFVFLDEATSALDEESEDRLYQ 132
cbiO PRK13641
energy-coupling factor transporter ATPase;
17-96 6.61e-09

energy-coupling factor transporter ATPase;


Pssm-ID: 237456 [Multi-domain]  Cd Length: 287  Bit Score: 52.52  E-value: 6.61e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  17 PRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDiftgNKLRQDLIELWEERVINTRSMLLVTHSVEEAVMLSDRVCLL 96
Cdd:PRK13641  143 PFELSGGQMRRVAIAGVMAYEPEILCLDEPAAGLD----PEGRKEMMQLFKDYQKAGHTVILVTHNMDDVAEYADDVLVL 218
PRK13633 PRK13633
energy-coupling factor transporter ATPase;
2-93 7.85e-09

energy-coupling factor transporter ATPase;


Pssm-ID: 237453 [Multi-domain]  Cd Length: 280  Bit Score: 52.40  E-value: 7.85e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDiftgNKLRQDLIELWEErvINTRS---MLL 78
Cdd:PRK13633  127 ESLKKVGMYEYRRHAPHLLSGGQKQRVAIAGILAMRPECIIFDEPTAMLD----PSGRREVVNTIKE--LNKKYgitIIL 200

                          90
                  ....*....|....*
gi 1462843241  79 VTHSVEEAVMlSDRV 93
Cdd:PRK13633  201 ITHYMEEAVE-ADRI 214
ABCC_cytochrome_bd cd03247
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ...
 18-96 8.12e-09

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.


Pssm-ID: 213214 [Multi-domain]  Cd Length: 178  Bit Score: 51.16  E-value: 8.12e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  18 RELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVIntrsmLLVTH---SVEEAvmlsDRVC 94
Cdd:cd03247    97 RRFSGGERQRLALARILLQDAPIVLLDEPTVGLDPITERQLLSLIFEVLKDKTL-----IWITHhltGIEHM----DKIL 167


                  ..
gi 1462843241  95 LL 96
Cdd:cd03247   168 FL 169
ccmA TIGR01189
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ...
 2-51 8.51e-09

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]


Pssm-ID: 273491 [Multi-domain]  Cd Length: 198  Bit Score: 51.59  E-value: 8.51e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALD 51
Cdd:TIGR01189 110 DALAAVGLTGFEDLPAAQLSAGQQRRLALARLWLSRRPLWILDEPTTALD 159
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
 16-96 1.07e-08

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 52.11  E-value: 1.07e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  16 YPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEErvINtRSMLLVTHSVEEAVMLSDRVCL 95
Cdd:TIGR03269 424 YPDELSEGERHRVALAQVLIKEPRIVILDEPTGTMDPITKVDVTHSILKAREE--ME-QTFIIVSHDMDFVLDVCDRAAL 500


                  .
gi 1462843241  96 L 96
Cdd:TIGR03269 501 M 501
cbiO PRK13644
energy-coupling factor transporter ATPase;
7-128 1.37e-08

energy-coupling factor transporter ATPase;


Pssm-ID: 106587 [Multi-domain]  Cd Length: 274  Bit Score: 51.53  E-value: 1.37e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   7 IGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEErvinTRSMLLVTHSVEEa 86
Cdd:PRK13644  124 IGLEKYRHRSPKTLSGGQGQCVALAGILTMEPECLIFDEVTSMLDPDSGIAVLERIKKLHEK----GKTIVYITHNLEE- 198

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 1462843241  87 VMLSDRVCL-------LGGLPSTITDtfDIDIKRNQRTKESISSLVEKI 128
Cdd:PRK13644  199 LHDADRIIVmdrgkivLEGEPENVLS--DVSLQTLGLTPPSLIELAENL 245
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
 20-83 1.70e-08

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 51.87  E-value: 1.70e-08
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1462843241   20 LSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIElwEERVINTRSMLLVTHSV 83
Cdd:TIGR00957  761 LSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGKHIFEHVIG--PEGVLKNKTRILVTHGI 822
ABCC_Protease_Secretion cd03246
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...
 20-96 2.91e-08

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.


Pssm-ID: 213213 [Multi-domain]  Cd Length: 173  Bit Score: 49.91  E-value: 2.91e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1462843241  20 LSGGMRQRVGFARALAVEPDLLLMDEPFSALDIfTGNKLRQDLIELWEERVInTRsmLLVTHSvEEAVMLSDRVCLL 96
Cdd:cd03246    97 LSGGQRQRLGLARALYGNPRILVLDEPNSHLDV-EGERALNQAIAALKAAGA-TR--IVIAHR-PETLASADRILVL 168
ABCC_Hemolysin cd03252
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...
 20-96 3.04e-08

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.


Pssm-ID: 213219 [Multi-domain]  Cd Length: 237  Bit Score: 50.56  E-value: 3.04e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1462843241  20 LSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLielweERVINTRSMLLVTHSVeEAVMLSDRVCLL 96
Cdd:cd03252   139 LSGGQRQRIAIARALIHNPRILIFDEATSALDYESEHAIMRNM-----HDICAGRTVIIIAHRL-STVKNADRIIVM 209
nikD PRK10418
nickel transporter ATP-binding protein NikD; Provisional
 14-93 3.31e-08

nickel transporter ATP-binding protein NikD; Provisional


Pssm-ID: 236688 [Multi-domain]  Cd Length: 254  Bit Score: 50.47  E-value: 3.31e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  14 KAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLrQDLIelweERVINTRS--MLLVTHSVEEAVMLSD 91
Cdd:PRK10418  135 KLYPFEMSGGMLQRMMIALALLCEAPFIIADEPTTDLDVVAQARI-LDLL----ESIVQKRAlgMLLVTHDMGVVARLAD 209


                  ..
gi 1462843241  92 RV 93
Cdd:PRK10418  210 DV 211
PRK11174 PRK11174
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 20-85 3.92e-08

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236870 [Multi-domain]  Cd Length: 588  Bit Score: 50.61  E-value: 3.92e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1462843241  20 LSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWeerviNTRSMLLVTHSVEE 85
Cdd:PRK11174  486 LSVGQAQRLALARALLQPCQLLLLDEPTASLDAHSEQLVMQALNAAS-----RRQTTLMVTHQLED 546
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
 20-96 4.51e-08

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 50.68  E-value: 4.51e-08
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1462843241   20 LSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTgnklRQDLIELWEERVINTRSMLLVTHSVEEaVMLSDRVCLL 96
Cdd:TIGR01271  549 LSGGQRARISLARAVYKDADLYLLDSPFTHLDVVT----EKEIFESCLCKLMSNKTRILVTSKLEH-LKKADKILLL 620
type_I_sec_PrtD TIGR01842
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ...
 20-81 4.73e-08

type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 200134 [Multi-domain]  Cd Length: 544  Bit Score: 50.42  E-value: 4.73e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1462843241  20 LSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVIntrsMLLVTH 81
Cdd:TIGR01842 455 LSGGQRQRIALARALYGDPKLVVLDEPNSNLDEEGEQALANAIKALKARGIT----VVVITH 512
NHLM_micro_ABC1 TIGR03796
NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein; This protein describes ...
 18-51 6.25e-08

NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein; This protein describes a multidomain ABC transporter subunit that is one of three protein families associated with some regularity with a distinctive family of putative bacteriocins. It includes a bacteriocin-processing peptidase domain at the N-terminus. Model TIGR03793 describes a conserved propeptide region for this bacteriocin family, unusual because it shows obvious homology a region of the enzyme nitrile hydratase up to the classic Gly-Gly cleavage motif. This family is therefore predicted to be a subunit of a bacteriocin processing and export system characteristic to this system that we designate NHLM, Nitrile Hydratase Leader Microcin. [Transport and binding proteins, Amino acids, peptides and amines, Cellular processes, Biosynthesis of natural products]


Pssm-ID: 274788 [Multi-domain]  Cd Length: 710  Bit Score: 49.94  E-value: 6.25e-08
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1462843241  18 RELSGGMRQRVGFARALAVEPDLLLMDEPFSALD 51
Cdd:TIGR03796 614 ANLSGGQRQRLEIARALVRNPSILILDEATSALD 647
LivF COG0410
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ...
 20-96 6.72e-08

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];


Pssm-ID: 440179 [Multi-domain]  Cd Length: 236  Bit Score: 49.21  E-value: 6.72e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  20 LSGGMRQRVGFARALAVEPDLLLMDEPFSAL------DIFtgnklrqDLIelweeRVINTR--SMLLVTHSVEEAVMLSD 91
Cdd:COG0410   137 LSGGEQQMLAIGRALMSRPKLLLLDEPSLGLapliveEIF-------EII-----RRLNREgvTILLVEQNARFALEIAD 204


                  ....*
gi 1462843241  92 RVCLL 96
Cdd:COG0410   205 RAYVL 209
ABCC_CFTR1 cd03291
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ...
 20-96 6.92e-08

ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213258 [Multi-domain]  Cd Length: 282  Bit Score: 49.86  E-value: 6.92e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1462843241  20 LSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTgnklRQDLIELWEERVINTRSMLLVTHSVEEaVMLSDRVCLL 96
Cdd:cd03291   160 LSGGQRARISLARAVYKDADLYLLDSPFGYLDVFT----EKEIFESCVCKLMANKTRILVTSKMEH-LKKADKILIL 231
ABCG_EPDR cd03213
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...
 18-96 7.03e-08

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.


Pssm-ID: 213180 [Multi-domain]  Cd Length: 194  Bit Score: 49.09  E-value: 7.03e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  18 RELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEErvinTRSMLLVTHSV-EEAVMLSDRVCLL 96
Cdd:cd03213   110 RGLSGGERKRVSIALELVSNPSLLFLDEPTSGLDSSSALQVMSLLRRLADT----GRTIICSIHQPsSEIFELFDKLLLL 185
ABC_CcmA_heme_exporter cd03231
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ...
 2-51 7.85e-08

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.


Pssm-ID: 213198 [Multi-domain]  Cd Length: 201  Bit Score: 49.03  E-value: 7.85e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALD 51
Cdd:cd03231   108 EALARVGLNGFEDRPVAQLSAGQQRRVALARLLLSGRPLWILDEPTTALD 157
PRK13657 PRK13657
glucan ABC transporter ATP-binding protein/ permease;
18-69 8.03e-08

glucan ABC transporter ATP-binding protein/ permease;


Pssm-ID: 184214 [Multi-domain]  Cd Length: 588  Bit Score: 49.57  E-value: 8.03e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1462843241  18 RELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEER 69
Cdd:PRK13657  470 RQLSGGERQRLAIARALLKDPPILILDEATSALDVETEAKVKAALDELMKGR 521
ArpD COG4618
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ...
 20-51 9.24e-08

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443660 [Multi-domain]  Cd Length: 563  Bit Score: 49.36  E-value: 9.24e-08
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1462843241  20 LSGGMRQRVGFARALAVEPDLLLMDEPFSALD 51
Cdd:COG4618   468 LSGGQRQRIGLARALYGDPRLVVLDEPNSNLD 499
PLN03073 PLN03073
ABC transporter F family; Provisional
 18-52 9.31e-08

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 49.47  E-value: 9.31e-08
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1462843241  18 RELSGGMRQRVGFARALAVEPDLLLMDEPFSALDI 52
Cdd:PLN03073  343 KTFSGGWRMRIALARALFIEPDLLLLDEPTNHLDL 377
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
18-101 9.37e-08

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 49.42  E-value: 9.37e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  18 RELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIftgnklrqdlielwEERVINTR-----------SMLLVTHSVEEA 86
Cdd:PRK13409  452 KDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDV--------------EQRLAVAKairriaeereaTALVVDHDIYMI 517

                          90
                  ....*....|....*
gi 1462843241  87 VMLSDRVCLLGGLPS 101
Cdd:PRK13409  518 DYISDRLMVFEGEPG 532
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
 2-54 1.07e-07

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 49.56  E-value: 1.07e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1462843241   2 DMLDLIGLTGYEKAypRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFT 54
Cdd:PRK11147  141 EVLAQLGLDPDAAL--SSLSGGWLRKAALGRALVSNPDVLLLDEPTNHLDIET 191
ABCG_White cd03234
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...
 18-65 1.52e-07

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.


Pssm-ID: 213201 [Multi-domain]  Cd Length: 226  Bit Score: 48.42  E-value: 1.52e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1462843241  18 RELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIEL 65
Cdd:cd03234   142 KGISGGERRRVSIAVQLLWDPKVLILDEPTSGLDSFTALNLVSTLSQL 189
ABC_MTABC3_MDL1_MDL2 cd03249
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ...
 19-51 1.68e-07

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.


Pssm-ID: 213216 [Multi-domain]  Cd Length: 238  Bit Score: 48.30  E-value: 1.68e-07
                          10        20        30
                  ....*....|....*....|....*....|...
gi 1462843241  19 ELSGGMRQRVGFARALAVEPDLLLMDEPFSALD 51
Cdd:cd03249   139 QLSGGQKQRIAIARALLRNPKILLLDEATSALD 171
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
 16-93 1.93e-07

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 48.87  E-value: 1.93e-07
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1462843241   16 YPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERvinTRSMLLVTHSVeEAVMLSDRV 93
Cdd:PTZ00265  1355 YGKSLSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLIEKTIVDIKDKA---DKTIITIAHRI-ASIKRSDKI 1428
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
18-93 2.28e-07

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 48.48  E-value: 2.28e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1462843241  18 RELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIftGNKlrQDLIELWEERVINTRSMLLVTHSVEEAVMLSDRV 93
Cdd:COG1129   393 GNLSGGNQQKVVLAKWLATDPKVLILDEPTRGIDV--GAK--AEIYRLIRELAAEGKAVIVISSELPELLGLSDRI 464
cbiO PRK13647
cobalt transporter ATP-binding subunit; Provisional
 2-96 2.66e-07

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237457 [Multi-domain]  Cd Length: 274  Bit Score: 47.81  E-value: 2.66e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEErvinTRSMLLVTH 81
Cdd:PRK13647  121 EALKAVRMWDFRDKPPYHLSYGQKKRVAIAGVLAMDPDVIVLDEPMAYLDPRGQETLMEILDRLHNQ----GKTVIVATH 196

                          90
                  ....*....|....*
gi 1462843241  82 SVEEAVMLSDRVCLL 96
Cdd:PRK13647  197 DVDLAAEWADQVIVL 211
CeuD COG4604
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ...
 2-111 3.28e-07

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443654 [Multi-domain]  Cd Length: 252  Bit Score: 47.39  E-value: 3.28e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERvinTRSMLLVTH 81
Cdd:COG4604   118 EAIAYLDLEDLADRYLDELSGGQRQRAFIAMVLAQDTDYVLLDEPLNNLDMKHSVQMMKLLRRLADEL---GKTVVIVLH 194

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1462843241  82 SVEEAVMLSDRVCLL--GGL-----------PSTITDTFDIDI 111
Cdd:COG4604   195 DINFASCYADHIVAMkdGRVvaqgtpeeiitPEVLSDIYDTDI 237
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 3-96 3.94e-07

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 48.09  E-value: 3.94e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241    3 MLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIelweeRVINTRSMLLVTHS 82
Cdd:TIGR01257 1045 MLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEPTSGVDPYSRRSIWDLLL-----KYRSGRTIIMSTHH 1119

                           90
                   ....*....|....
gi 1462843241   83 VEEAVMLSDRVCLL 96
Cdd:TIGR01257 1120 MDEADLLGDRIAII 1133
PRK13538 PRK13538
cytochrome c biogenesis heme-transporting ATPase CcmA;
4-51 4.77e-07

cytochrome c biogenesis heme-transporting ATPase CcmA;


Pssm-ID: 184125 [Multi-domain]  Cd Length: 204  Bit Score: 46.72  E-value: 4.77e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1462843241   4 LDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALD 51
Cdd:PRK13538  114 LAQVGLAGFEDVPVRQLSAGQQRRVALARLWLTRAPLWILDEPFTAID 161
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 18-100 4.89e-07

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 47.47  E-value: 4.89e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  18 RELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIftgnklrqdlielwEERVINTR-----------SMLLVTHSVEEA 86
Cdd:COG1245   454 KDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDV--------------EQRLAVAKairrfaenrgkTAMVVDHDIYLI 519

                          90
                  ....*....|....
gi 1462843241  87 VMLSDRVCLLGGLP 100
Cdd:COG1245   520 DYISDRLMVFEGEP 533
ABCC_MsbA cd03251
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ...
 20-69 5.52e-07

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213218 [Multi-domain]  Cd Length: 234  Bit Score: 46.84  E-value: 5.52e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1462843241  20 LSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEER 69
Cdd:cd03251   139 LSGGQRQRIAIARALLKDPPILILDEATSALDTESERLVQAALERLMKNR 188
PRK13543 PRK13543
heme ABC exporter ATP-binding protein CcmA;
4-52 5.90e-07

heme ABC exporter ATP-binding protein CcmA;


Pssm-ID: 184129 [Multi-domain]  Cd Length: 214  Bit Score: 46.77  E-value: 5.90e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1462843241   4 LDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDI 52
Cdd:PRK13543  122 LAIVGLAGYEDTLVRQLSAGQKKRLALARLWLSPAPLWLLDEPYANLDL 170
cbiO PRK13652
cobalt transporter ATP-binding subunit; Provisional
 4-51 6.25e-07

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 172200 [Multi-domain]  Cd Length: 277  Bit Score: 47.11  E-value: 6.25e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1462843241   4 LDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALD 51
Cdd:PRK13652  122 LHMLGLEELRDRVPHHLSGGEKKRVAIAGVIAMEPQVLVLDEPTAGLD 169
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
 18-93 9.78e-07

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 46.58  E-value: 9.78e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1462843241  18 RELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVintrSMLLVTHSVEEAVMLSDRV 93
Cdd:PRK15439  402 RTLSGGNQQKVLIAKCLEASPQLLIVDEPTRGVDVSARNDIYQLIRSIAAQNV----AVLFISSDLEEIEQMADRV 473
PRK15112 PRK15112
peptide ABC transporter ATP-binding protein SapF;
16-93 1.03e-06

peptide ABC transporter ATP-binding protein SapF;


Pssm-ID: 185067 [Multi-domain]  Cd Length: 267  Bit Score: 46.32  E-value: 1.03e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1462843241  16 YPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVIntrSMLLVTHSVEEAVMLSDRV 93
Cdd:PRK15112  146 YPHMLAPGQKQRLGLARALILRPKVIIADEALASLDMSMRSQLINLMLELQEKQGI---SYIYVTQHLGMMKHISDQV 220
3a01208 TIGR00958
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
 20-81 1.04e-06

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273363 [Multi-domain]  Cd Length: 711  Bit Score: 46.64  E-value: 1.04e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1462843241  20 LSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQdlielWEERviNTRSMLLVTH 81
Cdd:TIGR00958 618 LSGGQKQRIAIARALVRKPRVLILDEATSALDAECEQLLQE-----SRSR--ASRTVLLIAH 672
SapD COG4170
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
14-96 1.34e-06

ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];


Pssm-ID: 443330 [Multi-domain]  Cd Length: 331  Bit Score: 46.05  E-value: 1.34e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  14 KAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELweeRVINTRSMLLVTHSVEEAVMLSDRV 93
Cdd:COG4170   153 NSYPHELTEGECQKVMIAMAIANQPRLLIADEPTNAMESTTQAQIFRLLARL---NQLQGTSILLISHDLESISQWADTI 229


                  ...
gi 1462843241  94 CLL 96
Cdd:COG4170   230 TVL 232
ABC_RNaseL_inhibitor cd03222
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ...
 19-101 1.60e-06

ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213189 [Multi-domain]  Cd Length: 177  Bit Score: 45.26  E-value: 1.60e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  19 ELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEErviNTRSMLLVTHSVEEAVMLSDRVCLLGG 98
Cdd:cd03222    71 DLSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNAARAIRRLSEE---GKKTALVVEHDLAVLDYLSDRIHVFEG 147


                  ...
gi 1462843241  99 LPS 101
Cdd:cd03222   148 EPG 150
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
2-96 2.00e-06

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 45.50  E-value: 2.00e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNklrqdliELWEE---RVINTRSMLL 78
Cdd:NF000106  127 ELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRN-------EVWDEvrsMVRDGATVLL 199

                          90
                  ....*....|....*...
gi 1462843241  79 VTHSVEEAVMLSDRVCLL 96
Cdd:NF000106  200 TTQYMEEAEQLAHELTVI 217
PRK10895 PRK10895
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
 18-92 2.24e-06

lipopolysaccharide ABC transporter ATP-binding protein; Provisional


Pssm-ID: 182817 [Multi-domain]  Cd Length: 241  Bit Score: 45.27  E-value: 2.24e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1462843241  18 RELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQdLIELWEERVIntrSMLLVTHSVEEAVMLSDR 92
Cdd:PRK10895  136 QSLSGGERRRVEIARALAANPKFILLDEPFAGVDPISVIDIKR-IIEHLRDSGL---GVLITDHNVRETLAVCER 206
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
 20-79 2.43e-06

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 45.39  E-value: 2.43e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  20 LSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTgnklRQDLIELWEErvINTRSMLLV 79
Cdd:PRK10938  136 LSTGETRKTLLCQALMSEPDLLILDEPFDGLDVAS----RQQLAELLAS--LHQSGITLV 189
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
18-93 2.57e-06

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 45.39  E-value: 2.57e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  18 RELSGGMRQRVGFARALAVEPDLLLMDEPFSALDiftgnklRQDLIELWeeRVINT-----RSMLLVTHSVEEAVMLSDR 92
Cdd:COG1129   139 GDLSVAQQQLVEIARALSRDARVLILDEPTASLT-------EREVERLF--RIIRRlkaqgVAIIYISHRLDEVFEIADR 209


                  .
gi 1462843241  93 V 93
Cdd:COG1129   210 V 210
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 18-101 2.67e-06

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 45.16  E-value: 2.67e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  18 RELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIF---TGNKLRQDLIElweerviNTRSMLLVTHSVeeAV--MLSDR 92
Cdd:COG1245   211 SELSGGELQRVAIAAALLRDADFYFFDEPSSYLDIYqrlNVARLIRELAE-------EGKYVLVVEHDL--AIldYLADY 281


                  ....*....
gi 1462843241  93 VCLLGGLPS 101
Cdd:COG1245   282 VHILYGEPG 290
MsbA_lipidA TIGR02203
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ...
 20-96 3.07e-06

lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]


Pssm-ID: 131258 [Multi-domain]  Cd Length: 571  Bit Score: 45.09  E-value: 3.07e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  20 LSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLielweERVINTRSMLLVTH---SVEEAvmlsDRVCLL 96
Cdd:TIGR02203 470 LSGGQRQRLAIARALLKDAPILILDEATSALDNESERLVQAAL-----ERLMQGRTTLVIAHrlsTIEKA----DRIVVM 540
PTZ00243 PTZ00243
ABC transporter; Provisional
 20-98 3.26e-06

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 45.15  E-value: 3.26e-06
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1462843241   20 LSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIelweERVINTRSMLLVTHSVeEAVMLSDRVCLLGG 98
Cdd:PTZ00243   783 LSGGQKARVSLARAVYANRDVYLLDDPLSALDAHVGERVVEECF----LGALAGKTRVLATHQV-HVVPRADYVVALGD 856
ABCC_Glucan_exporter_like cd03254
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ...
 20-69 3.61e-06

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213221 [Multi-domain]  Cd Length: 229  Bit Score: 44.52  E-value: 3.61e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1462843241  20 LSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEER 69
Cdd:cd03254   140 LSQGERQLLAIARAMLRDPKILILDEATSNIDTETEKLIQEALEKLMKGR 189
fecE PRK11231
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
19-110 4.21e-06

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;


Pssm-ID: 183044 [Multi-domain]  Cd Length: 255  Bit Score: 44.62  E-value: 4.21e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  19 ELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFtgnklRQ-DLIELWEERVINTRSMLLVTHSVEEAVMLSDRVCLL- 96
Cdd:PRK11231  138 DLSGGQRQRAFLAMVLAQDTPVVLLDEPTTYLDIN-----HQvELMRLMRELNTQGKTVVTVLHDLNQASRYCDHLVVLa 212

                          90       100
                  ....*....|....*....|....*.
gi 1462843241  97 -GGL-----------PSTITDTFDID 110
Cdd:PRK11231  213 nGHVmaqgtpeevmtPGLLRTVFDVE 238
PRK10575 PRK10575
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
2-52 4.98e-06

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;


Pssm-ID: 182561 [Multi-domain]  Cd Length: 265  Bit Score: 44.39  E-value: 4.98e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1462843241   2 DMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDI 52
Cdd:PRK10575  130 EAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDI 180
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
18-101 5.61e-06

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 44.41  E-value: 5.61e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  18 RELSGGMRQRVGFARALAVEPDLLLMDEPFSALDI---FTGNKLRQDLIElweervinTRSMLLVTHSVeeAV--MLSDR 92
Cdd:PRK13409  211 SELSGGELQRVAIAAALLRDADFYFFDEPTSYLDIrqrLNVARLIRELAE--------GKYVLVVEHDL--AVldYLADN 280


                  ....*....
gi 1462843241  93 VCLLGGLPS 101
Cdd:PRK13409  281 VHIAYGEPG 289
3a01204 TIGR00955
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...
 6-96 5.74e-06

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273361 [Multi-domain]  Cd Length: 617  Bit Score: 44.27  E-value: 5.74e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   6 LIGLTGYEKAypreLSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERvintRSMLLVTHSVEE 85
Cdd:TIGR00955 157 RIGVPGRVKG----LSGGERKRLAFASELLTDPPLLFCDEPTSGLDSFMAYSVVQVLKGLAQKG----KTIICTIHQPSS 228

                          90
                  ....*....|..
gi 1462843241  86 AVM-LSDRVCLL 96
Cdd:TIGR00955 229 ELFeLFDKIILM 240
PRK15093 PRK15093
peptide ABC transporter ATP-binding protein SapD;
14-96 5.86e-06

peptide ABC transporter ATP-binding protein SapD;


Pssm-ID: 185049 [Multi-domain]  Cd Length: 330  Bit Score: 44.41  E-value: 5.86e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  14 KAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEErviNTRSMLLVTHSVEEAVMLSDRV 93
Cdd:PRK15093  153 RSFPYELTEGECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLTRLNQN---NNTTILLISHDLQMLSQWADKI 229


                  ...
gi 1462843241  94 CLL 96
Cdd:PRK15093  230 NVL 232
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 20-81 6.16e-06

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 44.16  E-value: 6.16e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1462843241  20 LSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELweervinTRSMLLVTH 81
Cdd:TIGR03719 162 LSGGERRRVALCRLLLSKPDMLLLDEPTNHLDAESVAWLERHLQEY-------PGTVVAVTH 216
ATM1 COG5265
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ...
 20-54 6.38e-06

ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444078 [Multi-domain]  Cd Length: 605  Bit Score: 44.43  E-value: 6.38e-06
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1462843241  20 LSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFT 54
Cdd:COG5265   495 LSGGEKQRVAIARTLLKNPPILIFDEATSALDSRT 529
PRK11160 PRK11160
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 18-96 7.43e-06

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236865 [Multi-domain]  Cd Length: 574  Bit Score: 44.05  E-value: 7.43e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  18 RELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEErvintRSMLLVTHSVEE-AVMlsDRVCLL 96
Cdd:PRK11160  474 RQLSGGEQRRLGIARALLHDAPLLLLDEPTEGLDAETERQILELLAEHAQN-----KTVLMITHRLTGlEQF--DRICVM 546
ABC_FeS_Assembly cd03217
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ...
 20-81 8.55e-06

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.


Pssm-ID: 213184 [Multi-domain]  Cd Length: 200  Bit Score: 43.28  E-value: 8.55e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1462843241  20 LSGGMRQRVGFARALAVEPDLLLMDEPFSALDIfTGNKLRQDLIELWEERvinTRSMLLVTH 81
Cdd:cd03217   105 FSGGEKKRNEILQLLLLEPDLAILDEPDSGLDI-DALRLVAEVINKLREE---GKSVLIITH 162
PhnK COG1101
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 20-92 1.13e-05

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 440718 [Multi-domain]  Cd Length: 264  Bit Score: 43.15  E-value: 1.13e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1462843241  20 LSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKlrqdLIELWEERV----INTrsmLLVTHSVEEAVMLSDR 92
Cdd:COG1101   149 LSGGQRQALSLLMATLTKPKLLLLDEHTAALDPKTAAL----VLELTEKIVeennLTT---LMVTHNMEQALDYGNR 218
PRK10535 PRK10535
macrolide ABC transporter ATP-binding protein/permease MacB;
2-81 1.20e-05

macrolide ABC transporter ATP-binding protein/permease MacB;


Pssm-ID: 182528 [Multi-domain]  Cd Length: 648  Bit Score: 43.56  E-value: 1.20e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEErvinTRSMLLVTH 81
Cdd:PRK10535  127 ELLQRLGLEDRVEYQPSQLSGGQQQRVSIARALMNGGQVILADEPTGALDSHSGEEVMAILHQLRDR----GHTVIIVTH 202
MK0520 COG2401
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ...
 14-81 1.26e-05

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];


Pssm-ID: 441957 [Multi-domain]  Cd Length: 222  Bit Score: 43.02  E-value: 1.26e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1462843241  14 KAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVIntrSMLLVTH 81
Cdd:COG2401   131 LRRFKELSTGQKFRFRLALLLAERPKLLVIDEFCSHLDRQTAKRVARNLQKLARRAGI---TLVVATH 195
cbiO PRK13646
energy-coupling factor transporter ATPase;
17-93 1.29e-05

energy-coupling factor transporter ATPase;


Pssm-ID: 184205 [Multi-domain]  Cd Length: 286  Bit Score: 43.23  E-value: 1.29e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1462843241  17 PRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDiftgNKLRQDLIELWEE-RVINTRSMLLVTHSVEEAVMLSDRV 93
Cdd:PRK13646  143 PFQMSGGQMRKIAIVSILAMNPDIIVLDEPTAGLD----PQSKRQVMRLLKSlQTDENKTIILVSHDMNEVARYADEV 216
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
2-51 1.42e-05

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 43.19  E-value: 1.42e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALD 51
Cdd:NF033858  380 EMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTSGVD 429
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 7-96 1.49e-05

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 43.46  E-value: 1.49e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241    7 IGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEErvinTRSMLLVTHSVEEA 86
Cdd:TIGR01257 2058 LGLSLYADRLAGTYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNTIVSIIRE----GRAVVLTSHSMEEC 2133

                           90
                   ....*....|
gi 1462843241   87 VMLSDRVCLL 96
Cdd:TIGR01257 2134 EALCTRLAIM 2143
ABCC_MRP_domain2 cd03244
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ...
 20-96 1.50e-05

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213211 [Multi-domain]  Cd Length: 221  Bit Score: 42.87  E-value: 1.50e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  20 LSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQdlielweerVINT----RSMLLVTHSVeEAVMLSDRVCL 95
Cdd:cd03244   140 LSVGQRQLLCLARALLRKSKILVLDEATASVDPETDALIQK---------TIREafkdCTVLTIAHRL-DTIIDSDRILV 209


                  .
gi 1462843241  96 L 96
Cdd:cd03244   210 L 210
PLN03211 PLN03211
ABC transporter G-25; Provisional
 7-65 1.76e-05

ABC transporter G-25; Provisional


Pssm-ID: 215634 [Multi-domain]  Cd Length: 659  Bit Score: 42.94  E-value: 1.76e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1462843241   7 IGLTGYEK-----AYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIEL 65
Cdd:PLN03211  189 LGLTKCENtiignSFIRGISGGERKRVSIAHEMLINPSLLILDEPTSGLDATAAYRLVLTLGSL 252
PRK10789 PRK10789
SmdA family multidrug ABC transporter permease/ATP-binding protein;
20-71 2.18e-05

SmdA family multidrug ABC transporter permease/ATP-binding protein;


Pssm-ID: 182732 [Multi-domain]  Cd Length: 569  Bit Score: 42.78  E-value: 2.18e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1462843241  20 LSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVI 71
Cdd:PRK10789  452 LSGGQKQRISIARALLLNAEILILDDALSAVDGRTEHQILHNLRQWGEGRTV 503
cbiO PRK13642
energy-coupling factor transporter ATPase;
7-96 2.27e-05

energy-coupling factor transporter ATPase;


Pssm-ID: 184202 [Multi-domain]  Cd Length: 277  Bit Score: 42.39  E-value: 2.27e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   7 IGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVIntrSMLLVTHSVEEA 86
Cdd:PRK13642  128 VNMLDFKTREPARLSGGQKQRVAVAGIIALRPEIIILDESTSMLDPTGRQEIMRVIHEIKEKYQL---TVLSITHDLDEA 204

                          90
                  ....*....|
gi 1462843241  87 VMlSDRVCLL 96
Cdd:PRK13642  205 AS-SDRILVM 213
PRK11176 PRK11176
lipid A ABC transporter ATP-binding protein/permease MsbA;
20-74 2.28e-05

lipid A ABC transporter ATP-binding protein/permease MsbA;


Pssm-ID: 183016 [Multi-domain]  Cd Length: 582  Bit Score: 42.70  E-value: 2.28e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1462843241  20 LSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEER---VINTR 74
Cdd:PRK11176  481 LSGGQRQRIAIARALLRDSPILILDEATSALDTESERAIQAALDELQKNRtslVIAHR 538
cbiO PRK13636
cobalt transporter ATP-binding subunit; Provisional
 20-93 2.38e-05

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184196 [Multi-domain]  Cd Length: 283  Bit Score: 42.53  E-value: 2.38e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1462843241  20 LSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVIntrSMLLVTHSVEEAVMLSDRV 93
Cdd:PRK13636  142 LSFGQKKRVAIAGVLVMEPKVLVLDEPTAGLDPMGVSEIMKLLVEMQKELGL---TIIIATHDIDIVPLYCDNV 212
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
 19-81 2.58e-05

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 42.57  E-value: 2.58e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1462843241  19 ELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIftgNKLRqdlielWEERVINTRS--MLLVTH 81
Cdd:PRK15064  155 EVAPGWKLRVLLAQALFSNPDILLLDEPTNNLDI---NTIR------WLEDVLNERNstMIIISH 210
PRK10247 PRK10247
putative ABC transporter ATP-binding protein YbbL; Provisional
 19-85 2.58e-05

putative ABC transporter ATP-binding protein YbbL; Provisional


Pssm-ID: 182331 [Multi-domain]  Cd Length: 225  Bit Score: 42.01  E-value: 2.58e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1462843241  19 ELSGGMRQRVGFARALAVEPDLLLMDEPFSALDifTGNKLR-QDLI-ELWEERVIntrSMLLVTHSVEE 85
Cdd:PRK10247  137 ELSGGEKQRISLIRNLQFMPKVLLLDEITSALD--ESNKHNvNEIIhRYVREQNI---AVLWVTHDKDE 200
PRK09984 PRK09984
phosphonate ABC transporter ATP-binding protein;
4-96 2.62e-05

phosphonate ABC transporter ATP-binding protein;


Pssm-ID: 182182 [Multi-domain]  Cd Length: 262  Bit Score: 42.31  E-value: 2.62e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   4 LDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVIntrSMLLVTHSV 83
Cdd:PRK09984  137 LTRVGMVHFAHQRVSTLSGGQQQRVAIARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNDGI---TVVVTLHQV 213

                          90
                  ....*....|...
gi 1462843241  84 EEAVMLSDRVCLL 96
Cdd:PRK09984  214 DYALRYCERIVAL 226
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
 20-51 2.66e-05

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 42.41  E-value: 2.66e-05
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1462843241  20 LSGGMRQRVGFARALAVEPDLLLMDEPFSALD 51
Cdd:PRK11819  164 LSGGERRRVALCRLLLEKPDMLLLDEPTNHLD 195
PLN03130 PLN03130
ABC transporter C family member; Provisional
 20-51 3.35e-05

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 42.42  E-value: 3.35e-05
                           10        20        30
                   ....*....|....*....|....*....|..
gi 1462843241   20 LSGGMRQRVGFARALAVEPDLLLMDEPFSALD 51
Cdd:PLN03130   741 ISGGQKQRVSMARAVYSNSDVYIFDDPLSALD 772
PRK10253 PRK10253
iron-enterobactin ABC transporter ATP-binding protein;
20-68 4.44e-05

iron-enterobactin ABC transporter ATP-binding protein;


Pssm-ID: 182336 [Multi-domain]  Cd Length: 265  Bit Score: 41.51  E-value: 4.44e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1462843241  20 LSGGMRQRVGFARALAVEPDLLLMDEPFSALDIftgnKLRQDLIELWEE 68
Cdd:PRK10253  144 LSGGQRQRAWIAMVLAQETAIMLLDEPTTWLDI----SHQIDLLELLSE 188
PRK13539 PRK13539
cytochrome c biogenesis protein CcmA; Provisional
 18-64 4.72e-05

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 237421 [Multi-domain]  Cd Length: 207  Bit Score: 41.40  E-value: 4.72e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 1462843241  18 RELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIfTGNKLRQDLIE 64
Cdd:PRK13539  126 GYLSAGQKRRVALARLLVSNRPIWILDEPTAALDA-AAVALFAELIR 171
PLN03232 PLN03232
ABC transporter C family member; Provisional
 20-51 7.49e-05

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 41.50  E-value: 7.49e-05
                           10        20        30
                   ....*....|....*....|....*....|..
gi 1462843241   20 LSGGMRQRVGFARALAVEPDLLLMDEPFSALD 51
Cdd:PLN03232   741 ISGGQKQRVSMARAVYSNSDIYIFDDPLSALD 772
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
20-46 8.20e-05

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 41.26  E-value: 8.20e-05
                          10        20
                  ....*....|....*....|....*..
gi 1462843241  20 LSGGMRQRVGFARALAVEPDLLLMDEP 46
Cdd:NF033858  137 LSGGMKQKLGLCCALIHDPDLLILDEP 163
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
 1-86 1.08e-04

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 40.77  E-value: 1.08e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   1 MDMLDLIGLTGYEKAYP-RELSGGMRQRVGFARALAVEPDLLLMDEPFSALDiftgnKLRQDLIELWEERVI-NTRSMLL 78
Cdd:PRK10938  382 QQWLDILGIDKRTADAPfHSLSWGQQRLALIVRALVKHPTLLILDEPLQGLD-----PLNRQLVRRFVDVLIsEGETQLL 456


                  ....*....
gi 1462843241  79 -VTHSVEEA 86
Cdd:PRK10938  457 fVSHHAEDA 465
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
 19-51 1.13e-04

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 40.78  E-value: 1.13e-04
                           10        20        30
                   ....*....|....*....|....*....|...
gi 1462843241   19 ELSGGMRQRVGFARALAVEPDLLLMDEPFSALD 51
Cdd:PTZ00265   579 KLSGGQKQRISIARAIIRNPKILILDEATSSLD 611
znuC PRK09544
high-affinity zinc transporter ATPase; Reviewed
 18-95 1.36e-04

high-affinity zinc transporter ATPase; Reviewed


Pssm-ID: 181939 [Multi-domain]  Cd Length: 251  Bit Score: 40.10  E-value: 1.36e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1462843241  18 RELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIfTGNKLRQDLIElwEERVINTRSMLLVTHSVEEAVMLSDRV-CL 95
Cdd:PRK09544  119 QKLSGGETQRVLLARALLNRPQLLVLDEPTQGVDV-NGQVALYDLID--QLRRELDCAVLMVSHDLHLVMAKTDEVlCL 194
tagH PRK13545
teichoic acids export protein ATP-binding subunit; Provisional
 21-85 1.78e-04

teichoic acids export protein ATP-binding subunit; Provisional


Pssm-ID: 184130 [Multi-domain]  Cd Length: 549  Bit Score: 40.26  E-value: 1.78e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1462843241  21 SGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEerviNTRSMLLVTHSVEE 85
Cdd:PRK13545  145 SSGMKSRLGFAISVHINPDILVIDEALSVGDQTFTKKCLDKMNEFKE----QGKTIFFISHSLSQ 205
cbiO PRK13638
energy-coupling factor ABC transporter ATP-binding protein;
2-96 1.85e-04

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184198 [Multi-domain]  Cd Length: 271  Bit Score: 39.99  E-value: 1.85e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   2 DMLDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDiftgNKLRQDLIELWEERVINTRSMLLVTH 81
Cdd:PRK13638  119 EALTLVDAQHFRHQPIQCLSHGQKKRVAIAGALVLQARYLLLDEPTAGLD----PAGRTQMIAIIRRIVAQGNHVIISSH 194

                          90
                  ....*....|....*
gi 1462843241  82 SVEEAVMLSDRVCLL 96
Cdd:PRK13638  195 DIDLIYEISDAVYVL 209
PLN03073 PLN03073
ABC transporter F family; Provisional
 20-91 2.07e-04

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 39.84  E-value: 2.07e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1462843241  20 LSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVINTRSMLLVTHSVEEAVMLSD 91
Cdd:PLN03073  628 LSGGQKSRVAFAKITFKKPHILLLDEPSNHLDLDAVEALIQGLVLFQGGVLMVSHDEHLISGSVDELWVVSE 699
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 18-54 2.12e-04

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 39.66  E-value: 2.12e-04
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 1462843241  18 RELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFT 54
Cdd:COG0488   431 GVLSGGEKARLALAKLLLSPPNVLLLDEPTNHLDIET 467
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 18-93 2.18e-04

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 39.62  E-value: 2.18e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1462843241  18 RELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVintrSMLLVTHSVEEAVMLSDRV 93
Cdd:COG3845   401 RSLSGGNQQKVILARELSRDPKLLIAAQPTRGLDVGAIEFIHQRLLELRDAGA----AVLLISEDLDEILALSDRI 472
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
 20-97 2.19e-04

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 39.81  E-value: 2.19e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1462843241  20 LSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVintrSMLLVTHSVEEAVMLSDRVCLLG 97
Cdd:TIGR02633 404 LSGGNQQKAVLAKMLLTNPRVLILDEPTRGVDVGAKYEIYKLINQLAQEGV----AIIVVSSELAEVLGLSDRVLVIG 477
hmuV PRK13547
heme ABC transporter ATP-binding protein;
20-96 2.29e-04

heme ABC transporter ATP-binding protein;


Pssm-ID: 184132 [Multi-domain]  Cd Length: 272  Bit Score: 39.42  E-value: 2.29e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  20 LSGGMRQRVGFARALA---------VEPDLLLMDEPFSALDIFTGNKLR---QDLIELWEERVintrsmLLVTHSVEEAV 87
Cdd:PRK13547  146 LSGGELARVQFARVLAqlwpphdaaQPPRYLLLDEPTAALDLAHQHRLLdtvRRLARDWNLGV------LAIVHDPNLAA 219


                  ....*....
gi 1462843241  88 MLSDRVCLL 96
Cdd:PRK13547  220 RHADRIAML 228
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 19-54 2.62e-04

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 39.53  E-value: 2.62e-04
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1462843241  19 ELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFT 54
Cdd:TIGR03719 443 QLSGGERNRVHLAKTLKSGGNVLLLDEPTNDLDVET 478
livG PRK11300
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
 4-93 2.91e-04

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional


Pssm-ID: 183080 [Multi-domain]  Cd Length: 255  Bit Score: 39.20  E-value: 2.91e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241   4 LDLIGLTGYEKAYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVIntrSMLLVTHSV 83
Cdd:PRK11300  138 LERVGLLEHANRQAGNLAYGQQRRLEIARCMVTQPEILMLDEPAAGLNPKETKELDELIAELRNEHNV---TVLLIEHDM 214

                          90
                  ....*....|
gi 1462843241  84 EEAVMLSDRV 93
Cdd:PRK11300  215 KLVMGISDRI 224
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
 18-52 3.18e-04

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 39.38  E-value: 3.18e-04
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1462843241  18 RELSGGMRQRVGFARALAVEPDLLLMDEPFSALDI 52
Cdd:PRK10636  148 SDFSGGWRMRLNLAQALICRSDLLLLDEPTNHLDL 182
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
 20-93 3.78e-04

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 39.22  E-value: 3.78e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1462843241  20 LSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQdLIELWEERVIntrSMLLVTHSVEEAVMLSDRV 93
Cdd:PRK10762  396 LSGGNQQKVAIARGLMTRPKVLILDEPTRGVDVGAKKEIYQ-LINQFKAEGL---SIILVSSEMPEVLGMSDRI 465
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
 18-81 4.78e-04

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 38.78  E-value: 4.78e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1462843241  18 RELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTgnklrqdlIELWEERVIN-TRSMLLVTH 81
Cdd:PRK11147  439 KALSGGERNRLLLARLFLKPSNLLILDEPTNDLDVET--------LELLEELLDSyQGTVLLVSH 495
BtuD COG4138
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ...
 20-52 6.17e-04

ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];


Pssm-ID: 443313 [Multi-domain]  Cd Length: 248  Bit Score: 38.28  E-value: 6.17e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1462843241  20 LSGGMRQRVGFARAL-----AVEPD--LLLMDEPFSALDI 52
Cdd:COG4138   127 LSGGEWQRVRLAAVLlqvwpTINPEgqLLLLDEPMNSLDV 166
ABCG_PDR_domain2 cd03232
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ...
 15-51 6.54e-04

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213199 [Multi-domain]  Cd Length: 192  Bit Score: 37.99  E-value: 6.54e-04
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 1462843241  15 AYPRELSGGMRQRVGFARALAVEPDLLLMDEPFSALD 51
Cdd:cd03232   104 ALLRGLSVEQRKRLTIGVELAAKPSILFLDEPTSGLD 140
livF PRK11614
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
20-92 1.04e-03

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;


Pssm-ID: 183231 [Multi-domain]  Cd Length: 237  Bit Score: 37.55  E-value: 1.04e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1462843241  20 LSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVintrSMLLVTHSVEEAVMLSDR 92
Cdd:PRK11614  138 MSGGEQQMLAIGRALMSQPRLLLLDEPSLGLAPIIIQQIFDTIEQLREQGM----TIFLVEQNANQALKLADR 206
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
19-109 1.17e-03

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 37.84  E-value: 1.17e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  19 ELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEErvinTRSMLLVTHSVEEAVMLSDRVCLL-- 96
Cdd:PRK09700  409 ELSGGNQQKVLISKWLCCCPEVIIFDEPTRGIDVGAKAEIYKVMRQLADD----GKVILMVSSELPEIITVCDRIAVFce 484

                          90
                  ....*....|...
gi 1462843241  97 GGLPSTITDTFDI 109
Cdd:PRK09700  485 GRLTQILTNRDDM 497
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 15-93 1.60e-03

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 37.31  E-value: 1.60e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  15 AYPRELSGGMRQRVGFARALAVEPDLLLMDEP------------FSALDiftgnKLRQDlielweervinTRSMLLVTHS 82
Cdd:COG3845   137 AKVEDLSVGEQQRVEILKALYRGARILILDEPtavltpqeadelFEILR-----RLAAE-----------GKSIIFITHK 200

                          90
                  ....*....|.
gi 1462843241  83 VEEAVMLSDRV 93
Cdd:COG3845   201 LREVMAIADRV 211
ABC_Class2 cd03227
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ...
 20-81 1.62e-03

ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.


Pssm-ID: 213194 [Multi-domain]  Cd Length: 162  Bit Score: 36.57  E-value: 1.62e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1462843241  20 LSGGMRQRVGFARALA----VEPDLLLMDEPFSALDIFTGNKlrqdLIELWEERVINTRSMLLVTH 81
Cdd:cd03227    78 LSGGEKELSALALILAlaslKPRPLYILDEIDRGLDPRDGQA----LAEAILEHLVKGAQVIVITH 139
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
 19-54 2.60e-03

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 36.64  E-value: 2.60e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1462843241  19 ELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFT 54
Cdd:PRK11819  445 VLSGGERNRLHLAKTLKQGGNVLLLDEPTNDLDVET 480
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
18-93 2.90e-03

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 36.43  E-value: 2.90e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1462843241  18 RELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERVintrSMLLVTHSVEEAVMLSDRV 93
Cdd:PRK11288  395 MNLSGGNQQKAILGRWLSEDMKVILLDEPTRGIDVGAKHEIYNVIYELAAQGV----AVLFVSSDLPEVLGVADRI 466
PRK03695 PRK03695
vitamin B12-transporter ATPase; Provisional
 20-113 3.01e-03

vitamin B12-transporter ATPase; Provisional


Pssm-ID: 235150 [Multi-domain]  Cd Length: 248  Bit Score: 36.06  E-value: 3.01e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  20 LSGGMRQRVGFARA-LAVEPD------LLLMDEPFSALDIFTGNKLRQDLIELWEErvinTRSMLLVTHSVEEAVMLSDR 92
Cdd:PRK03695  127 LSGGEWQRVRLAAVvLQVWPDinpagqLLLLDEPMNSLDVAQQAALDRLLSELCQQ----GIAVVMSSHDLNHTLRHADR 202

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1462843241  93 VCLL--GGL-----------PSTITDTFDIDIKR 113
Cdd:PRK03695  203 VWLLkqGKLlasgrrdevltPENLAQVFGVNFRR 236
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
 20-127 3.31e-03

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 36.25  E-value: 3.31e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1462843241  20 LSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEErvinTRSMLLVTHSVEEAVMLSDRVCLLG-G 98
Cdd:PRK10982  392 LSGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKFEIYQLIAELAKK----DKGIIIISSEMPELLGITDRILVMSnG 467

                          90       100
                  ....*....|....*....|....*....
gi 1462843241  99 LPSTITDTfdidikrNQRTKESISSLVEK 127
Cdd:PRK10982  468 LVAGIVDT-------KTTTQNEILRLASL 489
PRK13546 PRK13546
teichoic acids export ABC transporter ATP-binding subunit TagH;
18-85 5.29e-03

teichoic acids export ABC transporter ATP-binding subunit TagH;


Pssm-ID: 184131 [Multi-domain]  Cd Length: 264  Bit Score: 35.56  E-value: 5.29e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1462843241  18 RELSGGMRQRVGFARALAVEPDLLLMDEPFSALDIFTGNKLRQDLIELWEERvintRSMLLVTHSVEE 85
Cdd:PRK13546  142 KKYSSGMRAKLGFSINITVNPDILVIDEALSVGDQTFAQKCLDKIYEFKEQN----KTIFFVSHNLGQ 205
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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