DNA-binding transcriptional dual regulator of siderophore biosynthesis and transport [Vibrio tapetis subsp. tapetis]
transcriptional repressor( domain architecture ID 10793271)
transcriptional repressor such as ferric uptake regulators, iron-dependent, DNA-binding repressors and activators involved in iron metabolism, other metalloregulatory proteins, or the peroxide-responsive repressor PerR
List of domain hits
Name | Accession | Description | Interval | E-value | |||
fur | PRK09462 | ferric uptake regulator; Provisional |
1-148 | 3.76e-106 | |||
ferric uptake regulator; Provisional : Pssm-ID: 236527 Cd Length: 148 Bit Score: 298.95 E-value: 3.76e-106
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Name | Accession | Description | Interval | E-value | |||
fur | PRK09462 | ferric uptake regulator; Provisional |
1-148 | 3.76e-106 | |||
ferric uptake regulator; Provisional Pssm-ID: 236527 Cd Length: 148 Bit Score: 298.95 E-value: 3.76e-106
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FUR | pfam01475 | Ferric uptake regulator family; This family includes metal ion uptake regulator proteins, that ... |
10-130 | 1.25e-56 | |||
Ferric uptake regulator family; This family includes metal ion uptake regulator proteins, that bind to the operator DNA and controls transcription of metal ion-responsive genes. This family is also known as the FUR family. Pssm-ID: 426280 Cd Length: 121 Bit Score: 172.81 E-value: 1.25e-56
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Fur | COG0735 | Fe2+ or Zn2+ uptake regulation protein Fur/Zur [Inorganic ion transport and metabolism]; |
6-135 | 2.97e-53 | |||
Fe2+ or Zn2+ uptake regulation protein Fur/Zur [Inorganic ion transport and metabolism]; Pssm-ID: 440498 Cd Length: 140 Bit Score: 164.74 E-value: 2.97e-53
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Fur_like | cd07153 | Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, ... |
18-133 | 1.81e-45 | |||
Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Ferric uptake regulator (Fur) and related metalloregulatory proteins are iron-dependent, DNA-binding repressors and activators mainly involved in iron metabolism. A general model for Fur repression under iron-rich conditions is that activated Fur (a dimer having one Fe2+ coordinated per monomer) binds to specific DNA sequences (Fur boxes) in the promoter region of iron-responsive genes, hindering access of RNA polymerase, and repressing transcription. Positive regulation by Fur can be direct or indirect, as in the Fur repression of an anti-sense regulatory small RNA. Some members sense metal ions other than Fe2+. For example, the zinc uptake regulator (Zur) responds to Zn2+, the manganese uptake regulator (Mur) responds to Mn2+, and the nickel uptake regulator (Nur) responds to Ni2+. Other members sense signals other than metal ions. For example, PerR, a metal-dependent sensor of hydrogen peroxide. PerR regulates DNA-binding activity through metal-based protein oxidation, and co-ordinates Mn2+ or Fe2+ at its regulatory site. Fur family proteins contain an N-terminal winged-helix DNA-binding domain followed by a dimerization domain; this CD spans both those domains. Pssm-ID: 133478 [Multi-domain] Cd Length: 116 Bit Score: 144.26 E-value: 1.81e-45
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Name | Accession | Description | Interval | E-value | |||
fur | PRK09462 | ferric uptake regulator; Provisional |
1-148 | 3.76e-106 | |||
ferric uptake regulator; Provisional Pssm-ID: 236527 Cd Length: 148 Bit Score: 298.95 E-value: 3.76e-106
|
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FUR | pfam01475 | Ferric uptake regulator family; This family includes metal ion uptake regulator proteins, that ... |
10-130 | 1.25e-56 | |||
Ferric uptake regulator family; This family includes metal ion uptake regulator proteins, that bind to the operator DNA and controls transcription of metal ion-responsive genes. This family is also known as the FUR family. Pssm-ID: 426280 Cd Length: 121 Bit Score: 172.81 E-value: 1.25e-56
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Fur | COG0735 | Fe2+ or Zn2+ uptake regulation protein Fur/Zur [Inorganic ion transport and metabolism]; |
6-135 | 2.97e-53 | |||
Fe2+ or Zn2+ uptake regulation protein Fur/Zur [Inorganic ion transport and metabolism]; Pssm-ID: 440498 Cd Length: 140 Bit Score: 164.74 E-value: 2.97e-53
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Fur_like | cd07153 | Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, ... |
18-133 | 1.81e-45 | |||
Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Ferric uptake regulator (Fur) and related metalloregulatory proteins are iron-dependent, DNA-binding repressors and activators mainly involved in iron metabolism. A general model for Fur repression under iron-rich conditions is that activated Fur (a dimer having one Fe2+ coordinated per monomer) binds to specific DNA sequences (Fur boxes) in the promoter region of iron-responsive genes, hindering access of RNA polymerase, and repressing transcription. Positive regulation by Fur can be direct or indirect, as in the Fur repression of an anti-sense regulatory small RNA. Some members sense metal ions other than Fe2+. For example, the zinc uptake regulator (Zur) responds to Zn2+, the manganese uptake regulator (Mur) responds to Mn2+, and the nickel uptake regulator (Nur) responds to Ni2+. Other members sense signals other than metal ions. For example, PerR, a metal-dependent sensor of hydrogen peroxide. PerR regulates DNA-binding activity through metal-based protein oxidation, and co-ordinates Mn2+ or Fe2+ at its regulatory site. Fur family proteins contain an N-terminal winged-helix DNA-binding domain followed by a dimerization domain; this CD spans both those domains. Pssm-ID: 133478 [Multi-domain] Cd Length: 116 Bit Score: 144.26 E-value: 1.81e-45
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Blast search parameters | ||||
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