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Conserved domains on  [gi|1067578656|emb|SBN12588|]
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ABC transporter ATP-binding protein, iron related [Neisseria gonorrhoeae]

Protein Classification

ABC transporter ATP-binding protein( domain architecture ID 11467437)

ABC transporter ATP-binding protein is the ATPase catalytic subunit of an ATP transporter complex responsible for coupling the energy of ATP hydrolysis to the import of one or more from a variety of substrates including Fe(3+) ions and polyamines such as spermidine and putrescine

CATH:  3.40.50.300
EC:  7.-.-.-
Gene Ontology:  GO:0042626|GO:0140359|GO:0005524|GO:0016887
PubMed:  25750732|24638992
SCOP:  4003976
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 1-330 1.12e-139

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


:

Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 400.24  E-value: 1.12e-139
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   1 MTAALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRER 80
Cdd:COG3842     2 AMPALELENVSKRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDV----TGLPPEKR 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  81 RLGYLVQEGVLFPHLTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELI 160
Cdd:COG3842    78 NVGMVFQDYALFPHLTVAENVAFGLRMRGVPKAEIRARVAELLELVGLEGLADRYPHQLSGGQQQRVALARALAPEPRVL 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 161 LLDEPFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPADLDAALFIG 240
Cdd:COG3842   158 LLDEPLSALDAKLREEMREELRRLQRELGITFIYVTHDQEEALALADRIAVMNDGRIEQVGTPEEIYERPATRFVADFIG 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 241 EGIVFPAALNADGTADCRLG----RLPVQSGAPAGTRGTLLIRPEQFSLHPhSAPAASIHAVVLKTTPKARHTEISLRAG 316
Cdd:COG3842   238 EANLLPGTVLGDEGGGVRTGgrtlEVPADAGLAAGGPVTVAIRPEDIRLSP-EGPENGLPGTVEDVVFLGSHVRYRVRLG 316

                         330
                  ....*....|....*
gi 1067578656 317 Q-TVLTLNLPSAPTL 330
Cdd:COG3842   317 DgQELVVRVPNRAAL 331
 
Name Accession Description Interval E-value
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 1-330 1.12e-139

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 400.24  E-value: 1.12e-139
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   1 MTAALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRER 80
Cdd:COG3842     2 AMPALELENVSKRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDV----TGLPPEKR 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  81 RLGYLVQEGVLFPHLTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELI 160
Cdd:COG3842    78 NVGMVFQDYALFPHLTVAENVAFGLRMRGVPKAEIRARVAELLELVGLEGLADRYPHQLSGGQQQRVALARALAPEPRVL 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 161 LLDEPFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPADLDAALFIG 240
Cdd:COG3842   158 LLDEPLSALDAKLREEMREELRRLQRELGITFIYVTHDQEEALALADRIAVMNDGRIEQVGTPEEIYERPATRFVADFIG 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 241 EGIVFPAALNADGTADCRLG----RLPVQSGAPAGTRGTLLIRPEQFSLHPhSAPAASIHAVVLKTTPKARHTEISLRAG 316
Cdd:COG3842   238 EANLLPGTVLGDEGGGVRTGgrtlEVPADAGLAAGGPVTVAIRPEDIRLSP-EGPENGLPGTVEDVVFLGSHVRYRVRLG 316

                         330
                  ....*....|....*
gi 1067578656 317 Q-TVLTLNLPSAPTL 330
Cdd:COG3842   317 DgQELVVRVPNRAAL 331
ABC_Carb_Solutes_like cd03259
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...
 5-221 1.26e-109

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213226 [Multi-domain]  Cd Length: 213  Bit Score: 318.69  E-value: 1.26e-109
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRERRLGY 84
Cdd:cd03259     1 LELKGLSKTYGSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDV----TGVPPERRNIGM 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  85 LVQEGVLFPHLTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDE 164
Cdd:cd03259    77 VFQDYALFPHLTVAENIAFGLKLRGVPKAEIRARVRELLELVGLEGLLNRYPHELSGGQQQRVALARALAREPSLLLLDE 156

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1067578656 165 PFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTA 221
Cdd:cd03259   157 PLSALDAKLREELREELKELQRELGITTIYVTHDQEEALALADRIAVMNEGRIVQVG 213
PhnT2 TIGR03265
putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ...
 1-315 3.03e-100

putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ATP-binding protein is found in a number of genomes in operon-like contexts strongly suggesting a substrate specificity for 2-aminoethylphosphonate (2-AEP). The characterized PhnSTUV system is absent in the genomes in which this system is found. These genomes encode systems for the catabolism of 2-AEP, making the need for a 2-AEP-specific transporter likely. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274496 [Multi-domain]  Cd Length: 353  Bit Score: 300.03  E-value: 3.03e-100
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   1 MTAALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRER 80
Cdd:TIGR03265   1 SSPYLSIDNIRKRFGAFTALKDISLSVKKGEFVCLLGPSGCGKTTLLRIIAGLERQTAGTIYQGGRDI----TRLPPQKR 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  81 RLGYLVQEGVLFPHLTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELI 160
Cdd:TIGR03265  77 DYGIVFQSYALFPNLTVADNIAYGLKNRGMGRAEVAERVAELLDLVGLPGSERKYPGQLSGGQQQRVALARALATSPGLL 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 161 LLDEPFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPADLDAALFIG 240
Cdd:TIGR03265 157 LLDEPLSALDARVREHLRTEIRQLQRRLGVTTIMVTHDQEEALSMADRIVVMNHGVIEQVGTPQEIYRHPATPFVADFVG 236

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1067578656 241 EGIVFPAALNADGTADCRLGRLPV-QSGAPAGTRGTLLIRPEQFSLHPHSAPAASIHAVVLKTTPKARHTEISLRA 315
Cdd:TIGR03265 237 EVNWLPGTRGGGSRARVGGLTLACaPGLAQPGASVRLAVRPEDIRVSPAGNAANLLLARVEDMEFLGAFYRLRLRL 312
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
10-281 3.21e-88

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 269.89  E-value: 3.21e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  10 LSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRERRLGYLVQEG 89
Cdd:PRK09452   20 ISKSFDGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDI----THVPAENRHVNTVFQSY 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  90 VLFPHLTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSAL 169
Cdd:PRK09452   96 ALFPHMTVFENVAFGLRMQKTPAAEITPRVMEALRMVQLEEFAQRKPHQLSGGQQQRVAIARAVVNKPKVLLLDESLSAL 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 170 DEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPADLDAALFIGEGIVFPAAL 249
Cdd:PRK09452  176 DYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRIVVMRDGRIEQDGTPREIYEEPKNLFVARFIGEINIFDATV 255

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 1067578656 250 -----------NADGTaDCRL-GRLPVQsgapAGTRGTLLIRPE 281
Cdd:PRK09452  256 ierldeqrvraNVEGR-ECNIyVNFAVE----PGQKLHVLLRPE 294
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 20-167 1.17e-49

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 163.20  E-value: 1.17e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  20 LNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKntNLPVRERRLGYLVQEGVLFPHLTVYR 99
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDD--ERKSLRKEIGYVFQDPQLFPRLTVRE 78

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1067578656 100 NIAYGLGNGKGRTAQERQRIEAMLELTGISELA----GRYPHELSGGQQQRVALARALAPDPELILLDEPFS 167
Cdd:pfam00005  79 NLRLGLLLKGLSKREKDARAEEALEKLGLGDLAdrpvGERPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
ABC_ATP_DarD NF038007
darobactin export ABC transporter ATP-binding protein;
9-217 1.09e-45

darobactin export ABC transporter ATP-binding protein;


Pssm-ID: 411600 [Multi-domain]  Cd Length: 218  Bit Score: 155.26  E-value: 1.09e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   9 HLSKSFQnTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTI--FSKNTNLPVRERRLGYLV 86
Cdd:NF038007   11 YITKTIK-TKVLNHLNFSVEKGDFVSIMGPSGSGKSTLLNIIGMFDSLDSGSLTLAGKEVtnLSYSQKIILRRELIGYIF 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  87 QEGVLFPHLTVYRNIAYGLgngKGRTAQERQRIEAM---LELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLD 163
Cdd:NF038007   90 QSFNLIPHLSIFDNVALPL---KYRGVAKKERIERVnqvLNLFGIDNRRNHKPMQLSGGQQQRVAIARAMVSNPALLLAD 166

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1067578656 164 EPFSALDEQLRRQIREDMiAALRANGKSAVFVSHDrEEALQYADRIAVMKQGRI 217
Cdd:NF038007  167 EPTGNLDSKNARAVLQQL-KYINQKGTTIIMVTHS-DEASTYGNRIINMKDGKL 218
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
18-212 2.54e-38

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 135.05  E-value: 2.54e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  18 PVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKtifskntnlpvreRRLGYLVQEGVL---FPh 94
Cdd:NF040873    6 PVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRAGG-------------ARVAYVPQRSEVpdsLP- 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  95 LTVYRNIAYGLGNGKGR----TAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALD 170
Cdd:NF040873   72 LTVRDLVAMGRWARRGLwrrlTRDDRAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTGLD 151

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 1067578656 171 EQLRRQIReDMIAALRANGKSAVFVSHDREEALQyADRIAVM 212
Cdd:NF040873  152 AESRERII-ALLAEEHARGATVVVVTHDLELVRR-ADPCVLL 191
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
4-239 1.90e-23

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 101.74  E-value: 1.90e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   4 ALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKntnlpvRER--- 80
Cdd:NF033858    1 VARLEGVSHRYGKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVLGGDMADA------RHRrav 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  81 --RLGYLVQeGV---LFPHLTVYRNIA-----YGLGngkgrtAQER-QRIEAMLELTGISELAGRYPHELSGGQQQRVAL 149
Cdd:NF033858   75 cpRIAYMPQ-GLgknLYPTLSVFENLDffgrlFGQD------AAERrRRIDELLRATGLAPFADRPAGKLSGGMKQKLGL 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 150 ARALAPDPELILLDEPFSALDEQLRRQIREdMIAALRAN--GKSAVFVSHDREEALQYaDRIAVMKQGRILQTASPHELY 227
Cdd:NF033858  148 CCALIHDPDLLILDEPTTGVDPLSRRQFWE-LIDRIRAErpGMSVLVATAYMEEAERF-DWLVAMDAGRVLATGTPAELL 225

                         250
                  ....*....|....
gi 1067578656 228 RQ--PADLDAAlFI 239
Cdd:NF033858  226 ARtgADTLEAA-FI 238
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
9-240 2.94e-23

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 100.97  E-value: 2.94e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   9 HLSKSFQN-TPVlNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNtnLPVReRRLGYLVQ 87
Cdd:NF033858  271 GLTMRFGDfTAV-DHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQPVDAGD--IATR-RRVGYMSQ 346

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  88 EGVLFPHLTVYRNIA-----YGLGngkgrTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILL 162
Cdd:NF033858  347 AFSLYGELTVRQNLElharlFHLP-----AAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLIL 421

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 163 DEPFSALDEQLRRQIREDMIAALRaNGKSAVFVS-HDREEAlQYADRIAVMKQGRILQTASPHELY--RQPADLDAAlFI 239
Cdd:NF033858  422 DEPTSGVDPVARDMFWRLLIELSR-EDGVTIFIStHFMNEA-ERCDRISLMHAGRVLASDTPAALVaaRGAATLEEA-FI 498


                  .
gi 1067578656 240 G 240
Cdd:NF033858  499 A 499
GguA NF040905
sugar ABC transporter ATP-binding protein;
11-220 3.21e-19

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 88.31  E-value: 3.21e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  11 SKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAG------FEqpdsGEISLSGKTIFSKNTNlpvRERRLGY 84
Cdd:NF040905    8 TKTFPGVKALDDVNLSVREGEIHALCGENGAGKSTLMKVLSGvyphgsYE----GEILFDGEVCRFKDIR---DSEALGI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  85 LV--QEGVLFPHLTVYRNIAygLGNGKGRT-----AQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDP 157
Cdd:NF040905   81 VIihQELALIPYLSIAENIF--LGNERAKRgvidwNETNRRARELLAKVGLDESPDTLVTDIGVGKQQLVEIAKALSKDV 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1067578656 158 ELILLDEPFSALDEQLRRQIReDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQT 220
Cdd:NF040905  159 KLLILDEPTAALNEEDSAALL-DLLLELKAQGITSIIISHKLNEIRRVADSITVLRDGRTIET 220
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
116-303 8.37e-13

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 68.61  E-value: 8.37e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 116 RQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDEQLRRQIREDMIAALRaNGKSAVFV 195
Cdd:NF000106  122 RARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMVR-DGATVLLT 200

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 196 SHDREEALQYADRIAVMKQGRILQTASPHELYRQ------------PADLDAALfigeGIVFPAALN--ADGTADCRLG- 260
Cdd:NF000106  201 TQYMEEAEQLAHELTVIDRGRVIADGKVDELKTKvggrtlqirpahAAELDRMV----GAIAQAGLDgiAGATADHEDGv 276

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1067578656 261 -RLPV----QSGAPAGTRGTllirpEQFSLHPHSAPAASIHAVVLKTT 303
Cdd:NF000106  277 vNVPIvsdeQLSAVVGMLGE-----RGFTISGHQHPSAQL*EVFLAIT 319
GguA NF040905
sugar ABC transporter ATP-binding protein;
19-217 2.83e-11

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 64.43  E-value: 2.83e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  19 VLNDISLSLDPGEILFIIGASGCGKTTLLRCLAG--FEQPDSGEISLSGKTIFSKNTNLPVR-------ERRLGY-LVQE 88
Cdd:NF040905  275 VVDDVSLNVRRGEIVGIAGLMGAGRTELAMSVFGrsYGRNISGTVFKDGKEVDVSTVSDAIDaglayvtEDRKGYgLNLI 354

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  89 GvlfphlTVYRNI-AYGLG----------NGKGRTAQE---RQRIEAmlelTGISELAGRypheLSGGQQQRVALARALA 154
Cdd:NF040905  355 D------DIKRNItLANLGkvsrrgvideNEEIKVAEEyrkKMNIKT----PSVFQKVGN----LSGGNQQKVVLSKWLF 420

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1067578656 155 PDPELILLDEPFSALDEQLRRQIREdMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRI 217
Cdd:NF040905  421 TDPDVLILDEPTRGIDVGAKYEIYT-IINELAAEGKGVIVISSELPELLGMCDRIYVMNEGRI 482
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 29-201 3.42e-11

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 60.85  E-value: 3.42e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   29 PGEILFIIGASGCGKTTLLRCLAGFEQPDsgeislsGKTIFSKNTNlpvrerrlgylvqegvlfphltvyrniayglgng 108
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPP-------GGGVIYIDGE---------------------------------- 39

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  109 kgrtaqerqRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDEQLRRQIREDMIAAL--- 185
Cdd:smart00382  40 ---------DILEEVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLLEELRLlll 110

                          170
                   ....*....|....*...
gi 1067578656  186 --RANGKSAVFVSHDREE 201
Cdd:smart00382 111 lkSEKNLTVILTTNDEKD 128
 
Name Accession Description Interval E-value
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 1-330 1.12e-139

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 400.24  E-value: 1.12e-139
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   1 MTAALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRER 80
Cdd:COG3842     2 AMPALELENVSKRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDV----TGLPPEKR 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  81 RLGYLVQEGVLFPHLTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELI 160
Cdd:COG3842    78 NVGMVFQDYALFPHLTVAENVAFGLRMRGVPKAEIRARVAELLELVGLEGLADRYPHQLSGGQQQRVALARALAPEPRVL 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 161 LLDEPFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPADLDAALFIG 240
Cdd:COG3842   158 LLDEPLSALDAKLREEMREELRRLQRELGITFIYVTHDQEEALALADRIAVMNDGRIEQVGTPEEIYERPATRFVADFIG 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 241 EGIVFPAALNADGTADCRLG----RLPVQSGAPAGTRGTLLIRPEQFSLHPhSAPAASIHAVVLKTTPKARHTEISLRAG 316
Cdd:COG3842   238 EANLLPGTVLGDEGGGVRTGgrtlEVPADAGLAAGGPVTVAIRPEDIRLSP-EGPENGLPGTVEDVVFLGSHVRYRVRLG 316

                         330
                  ....*....|....*
gi 1067578656 317 Q-TVLTLNLPSAPTL 330
Cdd:COG3842   317 DgQELVVRVPNRAAL 331
CysA COG1118
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ...
 5-318 4.97e-121

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440735 [Multi-domain]  Cd Length: 348  Bit Score: 352.53  E-value: 4.97e-121
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFsknTNLPVRERRLGY 84
Cdd:COG1118     3 IEVRNISKRFGSFTLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLNGRDLF---TNLPPRERRVGF 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  85 LVQEGVLFPHLTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDE 164
Cdd:COG1118    80 VFQHYALFPHMTVAENIAFGLRVRPPSKAEIRARVEELLELVQLEGLADRYPSQLSGGQRQRVALARALAVEPEVLLLDE 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 165 PFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPADLDAALFIGEGIV 244
Cdd:COG1118   160 PFGALDAKVRKELRRWLRRLHDELGGTTVFVTHDQEEALELADRVVVMNQGRIEQVGTPDEVYDRPATPFVARFLGCVNV 239

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1067578656 245 FPAALnADGTADCRLGRLPVQSGAPAGTrGTLLIRPEQFSLHPHSAPAASIHAVVLKTTPKARHTEISLRAGQT 318
Cdd:COG1118   240 LRGRV-IGGQLEADGLTLPVAEPLPDGP-AVAGVRPHDIEVSREPEGENTFPATVARVSELGPEVRVELKLEDG 311
MalK COG3839
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ...
 3-347 9.64e-114

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];


Pssm-ID: 443050 [Multi-domain]  Cd Length: 352  Bit Score: 334.35  E-value: 9.64e-114
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   3 AALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRERRL 82
Cdd:COG3839     2 ASLELENVSKSYGGVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGGRDV----TDLPPKDRNI 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  83 GYLVQEGVLFPHLTVYRNIAYGLGNgKGRTAQER-QRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELIL 161
Cdd:COG3839    78 AMVFQSYALYPHMTVYENIAFPLKL-RKVPKAEIdRRVREAAELLGLEDLLDRKPKQLSGGQRQRVALGRALVREPKVFL 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 162 LDEPFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPADLDAALFIGE 241
Cdd:COG3839   157 LDEPLSNLDAKLRVEMRAEIKRLHRRLGTTTIYVTHDQVEAMTLADRIAVMNDGRIQQVGTPEELYDRPANLFVAGFIGS 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 242 G--IVFPAALNADG--TADCRLgRLPVQSGAPAGTRGTLLIRPEQFSLHPhsAPAASIHAVVLKTTPKARHTEISLRAGQ 317
Cdd:COG3839   237 PpmNLLPGTVEGGGvrLGGVRL-PLPAALAAAAGGEVTLGIRPEHLRLAD--EGDGGLEATVEVVEPLGSETLVHVRLGG 313

                         330       340       350
                  ....*....|....*....|....*....|
gi 1067578656 318 TVLTLNLPSAPTLSDGISAVLHLDGPALFF 347
Cdd:COG3839   314 QELVARVPGDTRLRPGDTVRLAFDPERLHL 343
ABC_Carb_Solutes_like cd03259
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...
 5-221 1.26e-109

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213226 [Multi-domain]  Cd Length: 213  Bit Score: 318.69  E-value: 1.26e-109
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRERRLGY 84
Cdd:cd03259     1 LELKGLSKTYGSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDV----TGVPPERRNIGM 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  85 LVQEGVLFPHLTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDE 164
Cdd:cd03259    77 VFQDYALFPHLTVAENIAFGLKLRGVPKAEIRARVRELLELVGLEGLLNRYPHELSGGQQQRVALARALAREPSLLLLDE 156

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1067578656 165 PFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTA 221
Cdd:cd03259   157 PLSALDAKLREELREELKELQRELGITTIYVTHDQEEALALADRIAVMNEGRIVQVG 213
PhnT2 TIGR03265
putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ...
 1-315 3.03e-100

putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ATP-binding protein is found in a number of genomes in operon-like contexts strongly suggesting a substrate specificity for 2-aminoethylphosphonate (2-AEP). The characterized PhnSTUV system is absent in the genomes in which this system is found. These genomes encode systems for the catabolism of 2-AEP, making the need for a 2-AEP-specific transporter likely. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274496 [Multi-domain]  Cd Length: 353  Bit Score: 300.03  E-value: 3.03e-100
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   1 MTAALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRER 80
Cdd:TIGR03265   1 SSPYLSIDNIRKRFGAFTALKDISLSVKKGEFVCLLGPSGCGKTTLLRIIAGLERQTAGTIYQGGRDI----TRLPPQKR 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  81 RLGYLVQEGVLFPHLTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELI 160
Cdd:TIGR03265  77 DYGIVFQSYALFPNLTVADNIAYGLKNRGMGRAEVAERVAELLDLVGLPGSERKYPGQLSGGQQQRVALARALATSPGLL 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 161 LLDEPFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPADLDAALFIG 240
Cdd:TIGR03265 157 LLDEPLSALDARVREHLRTEIRQLQRRLGVTTIMVTHDQEEALSMADRIVVMNHGVIEQVGTPQEIYRHPATPFVADFVG 236

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1067578656 241 EGIVFPAALNADGTADCRLGRLPV-QSGAPAGTRGTLLIRPEQFSLHPHSAPAASIHAVVLKTTPKARHTEISLRA 315
Cdd:TIGR03265 237 EVNWLPGTRGGGSRARVGGLTLACaPGLAQPGASVRLAVRPEDIRVSPAGNAANLLLARVEDMEFLGAFYRLRLRL 312
ABC_PotA_N cd03300
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...
 9-240 4.99e-93

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213267 [Multi-domain]  Cd Length: 232  Bit Score: 277.20  E-value: 4.99e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   9 HLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRERRLGYLVQE 88
Cdd:cd03300     5 NVSKFYGGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDI----TNLPPHKRPVNTVFQN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  89 GVLFPHLTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSA 168
Cdd:cd03300    81 YALFPHLTVFENIAFGLRLKKLPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPKVLLLDEPLGA 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1067578656 169 LDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPADLDAALFIG 240
Cdd:cd03300   161 LDLKLRKDMQLELKRLQKELGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGTPEEIYEEPANRFVADFIG 232
TauB COG1116
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ...
 1-217 1.54e-89

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440733 [Multi-domain]  Cd Length: 260  Bit Score: 269.27  E-value: 1.54e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   1 MTAALHIGHLSKSFQ----NTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNtnlp 76
Cdd:COG1116     4 AAPALELRGVSKRFPtgggGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDGKPVTGPG---- 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  77 vreRRLGYLVQEGVLFPHLTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPD 156
Cdd:COG1116    80 ---PDRGVVFQEPALLPWLTVLDNVALGLELRGVPKAERRERARELLELVGLAGFEDAYPHQLSGGMRQRVAIARALAND 156

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1067578656 157 PELILLDEPFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQ--GRI 217
Cdd:COG1116   157 PEVLLMDEPFGALDALTRERLQDELLRLWQETGKTVLFVTHDVDEAVFLADRVVVLSArpGRI 219
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
10-281 3.21e-88

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 269.89  E-value: 3.21e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  10 LSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRERRLGYLVQEG 89
Cdd:PRK09452   20 ISKSFDGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDI----THVPAENRHVNTVFQSY 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  90 VLFPHLTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSAL 169
Cdd:PRK09452   96 ALFPHMTVFENVAFGLRMQKTPAAEITPRVMEALRMVQLEEFAQRKPHQLSGGQQQRVAIARAVVNKPKVLLLDESLSAL 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 170 DEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPADLDAALFIGEGIVFPAAL 249
Cdd:PRK09452  176 DYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRIVVMRDGRIEQDGTPREIYEEPKNLFVARFIGEINIFDATV 255

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 1067578656 250 -----------NADGTaDCRL-GRLPVQsgapAGTRGTLLIRPE 281
Cdd:PRK09452  256 ierldeqrvraNVEGR-ECNIyVNFAVE----PGQKLHVLLRPE 294
ABC_NrtD_SsuB_transporters cd03293
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...
 5-220 4.20e-87

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213260 [Multi-domain]  Cd Length: 220  Bit Score: 261.64  E-value: 4.20e-87
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQN----TPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKtifskntnlPVRE- 79
Cdd:cd03293     1 LEVRNVSKTYGGgggaVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGE---------PVTGp 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  80 -RRLGYLVQEGVLFPHLTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPE 158
Cdd:cd03293    72 gPDRGYVFQQDALLPWLTVLDNVALGLELQGVPKAEARERAEELLELVGLSGFENAYPHQLSGGMRQRVALARALAVDPD 151

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1067578656 159 LILLDEPFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQ--GRILQT 220
Cdd:cd03293   152 VLLLDEPFSALDALTREQLQEELLDIWRETGKTVLLVTHDIDEAVFLADRVVVLSArpGRIVAE 215
OpuBA COG1125
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ...
 9-242 5.56e-83

ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440742 [Multi-domain]  Cd Length: 306  Bit Score: 254.24  E-value: 5.56e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   9 HLSKSFQN-TPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNtnlPVRERR-LGYLV 86
Cdd:COG1125     6 NVTKRYPDgTVAVDDLSLTIPAGEFTVLVGPSGCGKTTTLRMINRLIEPTSGRILIDGEDIRDLD---PVELRRrIGYVI 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  87 QEGVLFPHLTVYRNIA---YGLGNGKGRTaqeRQRIEAMLELTGI--SELAGRYPHELSGGQQQRVALARALAPDPELIL 161
Cdd:COG1125    83 QQIGLFPHMTVAENIAtvpRLLGWDKERI---RARVDELLELVGLdpEEYRDRYPHELSGGQQQRVGVARALAADPPILL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 162 LDEPFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPADLDAALFIGE 241
Cdd:COG1125   160 MDEPFGALDPITREQLQDELLRLQRELGKTIVFVTHDIDEALKLGDRIAVMREGRIVQYDTPEEILANPANDFVADFVGA 239


                  .
gi 1067578656 242 G 242
Cdd:COG1125   240 D 240
ABC_CysA_sulfate_importer cd03296
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...
 7-241 1.13e-82

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213263 [Multi-domain]  Cd Length: 239  Bit Score: 251.10  E-value: 1.13e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   7 IGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRERRLGYLV 86
Cdd:cd03296     5 VRNVSKRFGDFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDA----TDVPVQERNVGFVF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  87 QEGVLFPHLTVYRNIAYGLGNGKGRT----AQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILL 162
Cdd:cd03296    81 QHYALFRHMTVFDNVAFGLRVKPRSErppeAEIRAKVHELLKLVQLDWLADRYPAQLSGGQRQRVALARALAVEPKVLLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 163 DEPFSALDEQLRRQIRedmiAALR----ANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPADLDAALF 238
Cdd:cd03296   161 DEPFGALDAKVRKELR----RWLRrlhdELHVTTVFVTHDQEEALEVADRVVVMNKGRIEQVGTPDEVYDHPASPFVYSF 236


                  ...
gi 1067578656 239 IGE 241
Cdd:cd03296   237 LGE 239
GlnQ COG1126
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ...
 5-232 2.90e-79

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440743 [Multi-domain]  Cd Length: 239  Bit Score: 242.21  E-value: 2.90e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNTNLPVRERRLGY 84
Cdd:COG1126     2 IEIENLHKSFGDLEVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGEDLTDSKKDINKLRRKVGM 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  85 LVQEGVLFPHLTVYRNIAYGLGNGKGRTAQE-RQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLD 163
Cdd:COG1126    82 VFQQFNLFPHLTVLENVTLAPIKVKKMSKAEaEERAMELLERVGLADKADAYPAQLSGGQQQRVAIARALAMEPKVMLFD 161

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1067578656 164 EPFSALDEQLrrqIRE--DMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPAD 232
Cdd:COG1126   162 EPTSALDPEL---VGEvlDVMRDLAKEGMTMVVVTHEMGFAREVADRVVFMDGGRIVEEGPPEEFFENPQH 229
3a0106s01 TIGR00968
sulfate ABC transporter, ATP-binding protein; [Transport and binding proteins, Anions]
 7-241 1.38e-77

sulfate ABC transporter, ATP-binding protein; [Transport and binding proteins, Anions]


Pssm-ID: 130041 [Multi-domain]  Cd Length: 237  Bit Score: 238.16  E-value: 1.38e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   7 IGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRERRLGYLV 86
Cdd:TIGR00968   3 IANISKRFGSFQALDDVNLEVPTGSLVALLGPSGSGKSTLLRIIAGLEQPDSGRIRLNGQDA----TRVHARDRKIGFVF 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  87 QEGVLFPHLTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPF 166
Cdd:TIGR00968  79 QHYALFKHLTVRDNIAFGLEIRKHPKAKIKARVEELLELVQLEGLGDRYPNQLSGGQRQRVALARALAVEPQVLLLDEPF 158

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1067578656 167 SALDEQLRRQIRedmiAALRANGK----SAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPADLDAALFIGE 241
Cdd:TIGR00968 159 GALDAKVRKELR----SWLRKLHDevhvTTVFVTHDQEEAMEVADRIVVMSNGKIEQIGSPDEVYDHPANPFVMSFLGE 233
PRK10851 PRK10851
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
7-322 1.63e-77

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;


Pssm-ID: 182778 [Multi-domain]  Cd Length: 353  Bit Score: 241.91  E-value: 1.63e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   7 IGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRERRLGYLV 86
Cdd:PRK10851    5 IANIKKSFGRTQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDV----SRLHARDRKVGFVF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  87 QEGVLFPHLTVYRNIAYGLGNGKGR----TAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILL 162
Cdd:PRK10851   81 QHYALFRHMTVFDNIAFGLTVLPRRerpnAAAIKAKVTQLLEMVQLAHLADRYPAQLSGGQKQRVALARALAVEPQILLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 163 DEPFSALDEQLRRQIREdMIAALRANGK-SAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPADLDAALFIGE 241
Cdd:PRK10851  161 DEPFGALDAQVRKELRR-WLRQLHEELKfTSVFVTHDQEEAMEVADRVVVMSQGNIEQAGTPDQVWREPATRFVLEFMGE 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 242 -----GIVFPAALNAdGTADCRLGRLPVQSGapagtRGTLLIRPEQFSLHPHSAPAASIHAVVLKTTPKARHTEISLRA- 315
Cdd:PRK10851  240 vnrlqGTIRGGQFHV-GAHRWPLGYTPAYQG-----PVDLFLRPWEVDISRRTSLDSPLPVQVLEVSPKGHYWQLVVQPl 313


                  ....*....
gi 1067578656 316 --GQTVLTL 322
Cdd:PRK10851  314 gwYNEPLTV 322
ABC_OpuCA_Osmoprotection cd03295
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...
 9-242 2.93e-77

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213262 [Multi-domain]  Cd Length: 242  Bit Score: 237.20  E-value: 2.93e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   9 HLSKSFQN-TPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNtnlPVRERR-LGYLV 86
Cdd:cd03295     5 NVTKRYGGgKKAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEDIREQD---PVELRRkIGYVI 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  87 QEGVLFPHLTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGI--SELAGRYPHELSGGQQQRVALARALAPDPELILLDE 164
Cdd:cd03295    82 QQIGLFPHMTVEENIALVPKLLKWPKEKIRERADELLALVGLdpAEFADRYPHELSGGQQQRVGVARALAADPPLLLMDE 161

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1067578656 165 PFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPADLDAALFIGEG 242
Cdd:cd03295   162 PFGALDPITRDQLQEEFKRLQQELGKTIVFVTHDIDEAFRLADRIAIMKNGEIVQVGTPDEILRSPANDFVAEFVGAD 239
potG PRK11607
putrescine ABC transporter ATP-binding subunit PotG;
1-253 1.30e-76

putrescine ABC transporter ATP-binding subunit PotG;


Pssm-ID: 183226 [Multi-domain]  Cd Length: 377  Bit Score: 240.51  E-value: 1.30e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   1 MTAALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRER 80
Cdd:PRK11607   16 LTPLLEIRNLTKSFDGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVDL----SHVPPYQR 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  81 RLGYLVQEGVLFPHLTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELI 160
Cdd:PRK11607   92 PINMMFQSYALFPHMTVEQNIAFGLKQDKLPKAEIASRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVALARSLAKRPKLL 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 161 LLDEPFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPADLDAALFIG 240
Cdd:PRK11607  172 LLDEPMGALDKKLRDRMQLEVVDILERVGVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGEPEEIYEHPTTRYSAEFIG 251

                         250
                  ....*....|...
gi 1067578656 241 EGIVFPAALNADG 253
Cdd:PRK11607  252 SVNVFEGVLKERQ 264
potA TIGR01187
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ...
 35-285 3.78e-76

spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 162242 [Multi-domain]  Cd Length: 325  Bit Score: 237.39  E-value: 3.78e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  35 IIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRERRLGYLVQEGVLFPHLTVYRNIAYGLGNGKGRTAQ 114
Cdd:TIGR01187   1 LLGPSGCGKTTLLRLLAGFEQPDSGSIMLDGEDV----TNVPPHLRHINMVFQSYALFPHMTVEENVAFGLKMRKVPRAE 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 115 ERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDEQLRRQIREDMIAALRANGKSAVF 194
Cdd:TIGR01187  77 IKPRVLEALRLVQLEEFADRKPHQLSGGQQQRVALARALVFKPKILLLDEPLSALDKKLRDQMQLELKTIQEQLGITFVF 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 195 VSHDREEALQYADRIAVMKQGRILQTASPHELYRQPADLDAALFIGEGIVFPAA-LNADGTADCRLGRLPVQSGA----- 268
Cdd:TIGR01187 157 VTHDQEEAMTMSDRIAIMRKGKIAQIGTPEEIYEEPANLFVARFIGEINVFEATvIERKSEQVVLAGVEGRRCDIytdvp 236

                         250
                  ....*....|....*...
gi 1067578656 269 -PAGTRGTLLIRPEQFSL 285
Cdd:TIGR01187 237 vEKDQPLHVVLRPEKIVI 254
ABC_ModC_like cd03299
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ...
 5-244 7.15e-75

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213266 [Multi-domain]  Cd Length: 235  Bit Score: 231.07  E-value: 7.15e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQNTpVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRERRLGY 84
Cdd:cd03299     1 LKVENLSKDWKEF-KLKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKDI----TNLPPEKRDISY 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  85 LVQEGVLFPHLTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDE 164
Cdd:cd03299    76 VPQNYALFPHMTVYKNIAYGLKKRKVDKKEIERKVLEIAEMLGIDHLLNRKPETLSGGEQQRVAIARALVVNPKILLLDE 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 165 PFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPADLDAALFIGEGIV 244
Cdd:cd03299   156 PFSALDVRTKEKLREELKKIRKEFGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPEEVFKKPKNEFVAEFLGFNNI 235
ABC_ModC_molybdenum_transporter cd03297
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...
 20-219 1.42e-74

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213264 [Multi-domain]  Cd Length: 214  Bit Score: 229.49  E-value: 1.42e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  20 LNDISLSLD---PGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIF--SKNTNLPVRERRLGYLVQEGVLFPH 94
Cdd:cd03297    10 LPDFTLKIDfdlNEEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGTVLFdsRKKINLPPQQRKIGLVFQQYALFPH 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  95 LTVYRNIAYGLGngKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDEQLR 174
Cdd:cd03297    90 LNVRENLAFGLK--RKRNREDRISVDELLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDRALR 167

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1067578656 175 RQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQ 219
Cdd:cd03297   168 LQLLPELKQIKKNLNIPVIFVTHDLSEAEYLADRIVVMEDGRLQY 212
ABC_MalK_N cd03301
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...
 9-221 2.90e-74

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.


Pssm-ID: 213268 [Multi-domain]  Cd Length: 213  Bit Score: 228.68  E-value: 2.90e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   9 HLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRERRLGYLVQE 88
Cdd:cd03301     5 NVTKRFGNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDV----TDLPPKDRDIAMVFQN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  89 GVLFPHLTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSA 168
Cdd:cd03301    81 YALYPHMTVYDNIAFGLKLRKVPKDEIDERVREVAELLQIEHLLDRKPKQLSGGQRQRVALGRAIVREPKVFLMDEPLSN 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1067578656 169 LDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTA 221
Cdd:cd03301   161 LDAKLRVQMRAELKRLQQRLGTTTIYVTHDQVEAMTMADRIAVMNDGQIQQIG 213
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
 2-233 4.50e-74

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 237.88  E-value: 4.50e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   2 TAALHIGHLSKSF-----QNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLP 76
Cdd:COG1123   258 EPLLEVRNLSKRYpvrgkGGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGKDL----TKLS 333

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  77 VRE-----RRLGYLVQ--EGVLFPHLTVYRNIAYGLGN-GKGRTAQERQRIEAMLELTGIS-ELAGRYPHELSGGQQQRV 147
Cdd:COG1123   334 RRSlrelrRRVQMVFQdpYSSLNPRMTVGDIIAEPLRLhGLLSRAERRERVAELLERVGLPpDLADRYPHELSGGQRQRV 413

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 148 ALARALAPDPELILLDEPFSALDEQLRRQIReDMIAALRAN-GKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHEL 226
Cdd:COG1123   414 AIARALALEPKLLILDEPTSALDVSVQAQIL-NLLRDLQRElGLTYLFISHDLAVVRYIADRVAVMYDGRIVEDGPTEEV 492


                  ....*..
gi 1067578656 227 YRQPADL 233
Cdd:COG1123   493 FANPQHP 499
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
5-229 1.41e-73

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 227.64  E-value: 1.41e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNTNlpVReRRLGY 84
Cdd:COG1131     1 IEVRGLTKRYGDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVARDPAE--VR-RRIGY 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  85 LVQEGVLFPHLTVYRNIAYgLGNGKGRTAQE-RQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLD 163
Cdd:COG1131    78 VPQEPALYPDLTVRENLRF-FARLYGLPRKEaRERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPELLILD 156

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1067578656 164 EPFSALDEQLRRQIReDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQ 229
Cdd:COG1131   157 EPTSGLDPEARRELW-ELLRELAAEGKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDELKAR 221
EcfA2 COG1122
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...
 9-235 1.49e-73

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];


Pssm-ID: 440739 [Multi-domain]  Cd Length: 230  Bit Score: 227.22  E-value: 1.49e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   9 HLSKSFQN-TPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNTNlPVReRRLGYLVQ 87
Cdd:COG1122     5 NLSFSYPGgTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDITKKNLR-ELR-RKVGLVFQ 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  88 egvlFP-----HLTVYRNIAYGLGNgKGRTAQE-RQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELIL 161
Cdd:COG1122    83 ----NPddqlfAPTVEEDVAFGPEN-LGLPREEiRERVEEALELVGLEHLADRPPHELSGGQKQRVAIAGVLAMEPEVLV 157

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1067578656 162 LDEPFSALDEQLRRQIREdMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPADLDA 235
Cdd:COG1122   158 LDEPTAGLDPRGRRELLE-LLKRLNKEGKTVIIVTHDLDLVAELADRVIVLDDGRIVADGTPREVFSDYELLEE 230
MlaF COG1127
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...
 1-226 2.60e-73

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440744 [Multi-domain]  Cd Length: 241  Bit Score: 227.17  E-value: 2.60e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   1 MTAALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRE- 79
Cdd:COG1127     2 SEPMIEVRNLTKSFGDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQDI----TGLSEKEl 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  80 ----RRLGYLVQEGVLFPHLTVYRNIAYGLGNGKGRTAQE-RQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALA 154
Cdd:COG1127    78 yelrRRIGMLFQGGALFDSLTVFENVAFPLREHTDLSEAEiRELVLEKLELVGLPGAADKMPSELSGGMRKRVALARALA 157

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1067578656 155 PDPELILLDEPFSALDEQLRRQIrEDMIAALR-ANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHEL 226
Cdd:COG1127   158 LDPEILLYDEPTAGLDPITSAVI-DELIRELRdELGLTSVVVTHDLDSAFAIADRVAVLADGKIIAEGTPEEL 229
fbpC PRK11432
ferric ABC transporter ATP-binding protein;
9-342 2.25e-72

ferric ABC transporter ATP-binding protein;


Pssm-ID: 183133 [Multi-domain]  Cd Length: 351  Bit Score: 228.45  E-value: 2.25e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   9 HLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRERRLGYLVQE 88
Cdd:PRK11432   11 NITKRFGSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDV----THRSIQQRDICMVFQS 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  89 GVLFPHLTVYRNIAYGLgNGKGRTAQER-QRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFS 167
Cdd:PRK11432   87 YALFPHMSLGENVGYGL-KMLGVPKEERkQRVKEALELVDLAGFEDRYVDQISGGQQQRVALARALILKPKVLLFDEPLS 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 168 ALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPADLDAALFIGEGIVFPA 247
Cdd:PRK11432  166 NLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGSPQELYRQPASRFMASFMGDANIFPA 245

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 248 ALNADgTADCRLGRLP----VQSGAPAGTrGTLLIRPEQFSLHPHSAPA--ASIHAVVLkttpKARHTEISLR-AGQTVL 320
Cdd:PRK11432  246 TLSGD-YVDIYGYRLPrpaaFAFNLPDGE-CTVGVRPEAITLSEQGEESqrCTIKHVAY----MGPQYEVTVDwHGQELL 319

                         330       340
                  ....*....|....*....|....*
gi 1067578656 321 tLNLPSA---PTLSDGISAVLHLDG 342
Cdd:PRK11432  320 -LQVNATqlqPDLGEHYYLEIHPYG 343
ABC_Pro_Gly_Betaine cd03294
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ...
 10-232 4.39e-72

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213261 [Multi-domain]  Cd Length: 269  Bit Score: 225.22  E-value: 4.39e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  10 LSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTI--FSKNTNLPVRERRLGYLVQ 87
Cdd:cd03294    30 ILKKTGQTVGVNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQDIaaMSRKELRELRRKKISMVFQ 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  88 EGVLFPHLTVYRNIAYGLgNGKGRTAQER-QRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPF 166
Cdd:cd03294   110 SFALLPHRTVLENVAFGL-EVQGVPRAEReERAAEALELVGLEGWEHKYPDELSGGMQQRVGLARALAVDPDILLMDEAF 188

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1067578656 167 SALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPAD 232
Cdd:cd03294   189 SALDPLIRREMQDELLRLQAELQKTIVFITHDLDEALRLGDRIAIMKDGRLVQVGTPEEILTNPAN 254
PhnT TIGR03258
2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; This ATP-binding ...
 2-319 1.49e-71

2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; This ATP-binding component of an ABC transport system is found in Salmonella and Burkholderia lineages in the vicinity of enzymes for the breakdown of 2-aminoethylphosphonate.


Pssm-ID: 132302 [Multi-domain]  Cd Length: 362  Bit Score: 226.80  E-value: 1.49e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   2 TAALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPD--SGEISLSGKTIfsknTNLPVRE 79
Cdd:TIGR03258   3 CGGIRIDHLRVAYGANTVLDDLSLEIEAGELLALIGKSGCGKTTLLRAIAGFVKAAglTGRIAIADRDL----THAPPHK 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  80 RRLGYLVQEGVLFPHLTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPEL 159
Cdd:TIGR03258  79 RGLALLFQNYALFPHLKVEDNVAFGLRAQKMPKADIAERVADALKLVGLGDAAAHLPAQLSGGMQQRIAIARAIAIEPDV 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 160 ILLDEPFSALDEQLRRQIREDmIAAL--RANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPADLDAAL 237
Cdd:TIGR03258 159 LLLDEPLSALDANIRANMREE-IAALheELPELTILCVTHDQDDALTLADKAGIMKDGRLAAHGEPQALYDAPADGFAAE 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 238 FIGEGIVFPA----ALNADGTADCRLGRLPVQS---GAPAGTRGTLLIRPEQFSLHPHSAPAASIHAVV--LKTTPKARH 308
Cdd:TIGR03258 238 FLGAANILPAialgITEAPGLVDVSCGGAVIFAfgdGRHDGRDKLACIRPEHLALTPRPAGEGRFHATIasVEWHGAALH 317

                         330
                  ....*....|.
gi 1067578656 309 TEISLRAGQTV 319
Cdd:TIGR03258 318 LLCDLDAACDE 328
ABC_MJ0796_LolCDE_FtsE cd03255
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...
 5-217 2.13e-71

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.


Pssm-ID: 213222 [Multi-domain]  Cd Length: 218  Bit Score: 221.59  E-value: 2.13e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQN----TPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNTN--LPVR 78
Cdd:cd03255     1 IELKNLSKTYGGggekVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLSEKelAAFR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  79 ERRLGYLVQEGVLFPHLTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPE 158
Cdd:cd03255    81 RRHIGFVFQSFNLLPDLTALENVELPLLLAGVPKKERRERAEELLERVGLGDRLNHYPSELSGGQQQRVAIARALANDPK 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1067578656 159 LILLDEPFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEAlQYADRIAVMKQGRI 217
Cdd:cd03255   161 IILADEPTGNLDSETGKEVMELLRELNKEAGTTIVVVTHDPELA-EYADRIIELRDGKI 218
LolD COG1136
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
1-217 2.97e-71

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440751 [Multi-domain]  Cd Length: 227  Bit Score: 221.46  E-value: 2.97e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   1 MTAALHIGHLSKSFQN----TPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKN---- 72
Cdd:COG1136     1 MSPLLELRNLTKSYGTgegeVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISSLSerel 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  73 TNLpvRERRLGYLVQEGVLFPHLTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARA 152
Cdd:COG1136    81 ARL--RRRHIGFVFQFFNLLPELTALENVALPLLLAGVSRKERRERARELLERVGLGDRLDHRPSQLSGGQQQRVAIARA 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1067578656 153 LAPDPELILLDEPFSALDEQLRRQIREDMIAALRANGKSAVFVSHDrEEALQYADRIAVMKQGRI 217
Cdd:COG1136   159 LVNRPKLILADEPTGNLDSKTGEEVLELLRELNRELGTTIVMVTHD-PELAARADRVIRLRDGRI 222
ModC COG4148
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ...
 22-320 5.32e-71

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443319 [Multi-domain]  Cd Length: 358  Bit Score: 225.36  E-value: 5.32e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  22 DISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFS--KNTNLPVRERRLGYLVQEGVLFPHLTVYR 99
Cdd:COG4148    17 DVDFTLPGRGVTALFGPSGSGKTTLLRAIAGLERPDSGRIRLGGEVLQDsaRGIFLPPHRRRIGYVFQEARLFPHLSVRG 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 100 NIAYGLGNGkgRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDEQLRRQIRe 179
Cdd:COG4148    97 NLLYGRKRA--PRAERRISFDEVVELLGIGHLLDRRPATLSGGERQRVAIGRALLSSPRLLLMDEPLAALDLARKAEIL- 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 180 DMIAALRANGK-SAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPADLDAALFIGEGIVFPAAL----NADGT 254
Cdd:COG4148   174 PYLERLRDELDiPILYVSHSLDEVARLADHVVLLEQGRVVASGPLAEVLSRPDLLPLAGGEEAGSVLEATVaahdPDYGL 253

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1067578656 255 ADCRLG----RLPvQSGAPAGTRGTLLIRPEQFSLHPHSAPAASI----HAVVLKTTPKAR-HTEISLRAGQTVL 320
Cdd:COG4148   254 TRLALGggrlWVP-RLDLPPGTRVRVRIRARDVSLALEPPEGSSIlnilPGRVVEIEPADGgQVLVRLDLGGQTL 327
FepC COG1120
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...
 4-246 8.53e-71

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];


Pssm-ID: 440737 [Multi-domain]  Cd Length: 254  Bit Score: 221.07  E-value: 8.53e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   4 ALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRE--RR 81
Cdd:COG1120     1 MLEAENLSVGYGGRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDL----ASLSRRElaRR 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  82 LGYLVQEGVLFPHLTVYRNIAYG----LGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDP 157
Cdd:COG1120    77 IAYVPQEPPAPFGLTVRELVALGryphLGLFGRPSAEDREAVEEALERTGLEHLADRPVDELSGGERQRVLIARALAQEP 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 158 ELILLDEPFSALDeqLRRQIR-EDMIAAL-RANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHE---------L 226
Cdd:COG1120   157 PLLLLDEPTSHLD--LAHQLEvLELLRRLaRERGRTVVMVLHDLNLAARYADRLVLLKDGRIVAQGPPEEvltpelleeV 234

                         250       260
                  ....*....|....*....|
gi 1067578656 227 YRQPADLDAALFIGEGIVFP 246
Cdd:COG1120   235 YGVEARVIEDPVTGRPLVLP 254
ABC_Class3 cd03229
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...
 5-216 7.98e-70

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213196 [Multi-domain]  Cd Length: 178  Bit Score: 215.90  E-value: 7.98e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNTNLPVRERRLGY 84
Cdd:cd03229     1 LELKNVSKRYGQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLTDLEDELPPLRRRIGM 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  85 LVQEGVLFPHLTVYRNIAYGlgngkgrtaqerqrieamleltgiselagrypheLSGGQQQRVALARALAPDPELILLDE 164
Cdd:cd03229    81 VFQDFALFPHLTVLENIALG----------------------------------LSGGQQQRVALARALAMDPDVLLLDE 126

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1067578656 165 PFSALDEQLRRQIReDMIAALRAN-GKSAVFVSHDREEALQYADRIAVMKQGR 216
Cdd:cd03229   127 PTSALDPITRREVR-ALLKSLQAQlGITVVLVTHDLDEAARLADRVVVLRDGK 178
ABC_cobalt_CbiO_domain1 cd03225
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...
 9-216 1.26e-68

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213192 [Multi-domain]  Cd Length: 211  Bit Score: 214.25  E-value: 1.26e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   9 HLSKSF--QNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsKNTNLPVRERRLGYLV 86
Cdd:cd03225     4 NLSFSYpdGARPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDL--TKLSLKELRRKVGLVF 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  87 Q--EGVLFpHLTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDE 164
Cdd:cd03225    82 QnpDDQFF-GPTVEEEVAFGLENLGLPEEEIEERVEEALELVGLEGLRDRSPFTLSGGQKQRVAIAGVLAMDPDILLLDE 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1067578656 165 PFSALDEQLRRQIREdMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGR 216
Cdd:cd03225   161 PTAGLDPAGRRELLE-LLKKLKAEGKTIIIVTHDLDLLLELADRVIVLEDGK 211
ProV COG4175
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ...
 20-232 1.00e-67

ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443334 [Multi-domain]  Cd Length: 389  Bit Score: 217.66  E-value: 1.00e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  20 LNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTI--FSKNTNLPVRERRLGYLVQEGVLFPHLTV 97
Cdd:COG4175    43 VNDASFDVEEGEIFVIMGLSGSGKSTLVRCLNRLIEPTAGEVLIDGEDItkLSKKELRELRRKKMSMVFQHFALLPHRTV 122

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  98 YRNIAYGL---GNGKgrtAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDEQLR 174
Cdd:COG4175   123 LENVAFGLeiqGVPK---AERRERAREALELVGLAGWEDSYPDELSGGMQQRVGLARALATDPDILLMDEAFSALDPLIR 199

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1067578656 175 RQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPAD 232
Cdd:COG4175   200 REMQDELLELQAKLKKTIVFITHDLDEALRLGDRIAIMKDGRIVQIGTPEEILTNPAN 257
ABC_Org_Solvent_Resistant cd03261
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...
 9-226 1.26e-66

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213228 [Multi-domain]  Cd Length: 235  Bit Score: 209.67  E-value: 1.26e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   9 HLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIF--SKNTNLPVReRRLGYLV 86
Cdd:cd03261     5 GLTKSFGGRTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDISglSEAELYRLR-RRMGMLF 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  87 QEGVLFPHLTVYRNIAYGL-GNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEP 165
Cdd:cd03261    84 QSGALFDSLTVFENVAFPLrEHTRLSEEEIREIVLEKLEAVGLRGAEDLYPAELSGGMKKRVALARALALDPELLLYDEP 163

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1067578656 166 FSALDEQLRRQIrEDMIAAL-RANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHEL 226
Cdd:cd03261   164 TAGLDPIASGVI-DDLIRSLkKELGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGTPEEL 224
ABC_HisP_GlnQ cd03262
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ...
 5-217 1.29e-66

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.


Pssm-ID: 213229 [Multi-domain]  Cd Length: 213  Bit Score: 208.92  E-value: 1.29e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNTNLPVRERRLGY 84
Cdd:cd03262     1 IEIKNLHKSFGDFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKLTDDKKNINELRQKVGM 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  85 LVQEGVLFPHLTVYRNIAYGLGNGKGRTAQERQRI-EAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLD 163
Cdd:cd03262    81 VFQQFNLFPHLTVLENITLAPIKVKGMSKAEAEERaLELLEKVGLADKADAYPAQLSGGQQQRVAIARALAMNPKVMLFD 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1067578656 164 EPFSALDEQLRRQIrEDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRI 217
Cdd:cd03262   161 EPTSALDPELVGEV-LDVMKDLAEEGMTMVVVTHEMGFAREVADRVIFMDDGRI 213
ZnuC COG1121
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 1-217 4.91e-65

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440738 [Multi-domain]  Cd Length: 245  Bit Score: 206.09  E-value: 4.91e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   1 MTAALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNtnlpvreR 80
Cdd:COG1121     3 MMPAIELENLTVSYGGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGKPPRRAR-------R 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  81 RLGYLVQEGVL---FPhLTVYRNIAYGL----GNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARAL 153
Cdd:COG1121    76 RIGYVPQRAEVdwdFP-ITVRDVVLMGRygrrGLFRRPSRADREAVDEALERVGLEDLADRPIGELSGGQQQRVLLARAL 154

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1067578656 154 APDPELILLDEPFSALDEQLRRQIrEDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRI 217
Cdd:COG1121   155 AQDPDLLLLDEPFAGVDAATEEAL-YELLRELRREGKTILVVTHDLGAVREYFDRVLLLNRGLV 217
NatA COG4555
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ...
 9-238 9.42e-65

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 443618 [Multi-domain]  Cd Length: 243  Bit Score: 205.48  E-value: 9.42e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   9 HLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNtnlPVRERRLGYLVQE 88
Cdd:COG4555     6 NLSKKYGKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGEDVRKEP---REARRQIGVLPDE 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  89 GVLFPHLTVYRNIAYgLGNGKGRTAQE-RQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFS 167
Cdd:COG4555    83 RGLYDRLTVRENIRY-FAELYGLFDEElKKRIEELIELLGLEEFLDRRVGELSTGMKKKVALARALVHDPKVLLLDEPTN 161

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1067578656 168 ALDEQLRRQIREDmIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQ--PADLDAALF 238
Cdd:COG4555   162 GLDVMARRLLREI-LRALKKEGKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSLDELREEigEENLEDAFV 233
ugpC PRK11650
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
3-299 1.07e-64

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;


Pssm-ID: 236947 [Multi-domain]  Cd Length: 356  Bit Score: 208.93  E-value: 1.07e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   3 AALHIGHLSKSFQN-TPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRERR 81
Cdd:PRK11650    2 AGLKLQAVRKSYDGkTQVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWIGGRVV----NELEPADRD 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  82 LGYLVQEGVLFPHLTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELIL 161
Cdd:PRK11650   78 IAMVFQNYALYPHMSVRENMAYGLKIRGMPKAEIEERVAEAARILELEPLLDRKPRELSGGQRQRVAMGRAIVREPAVFL 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 162 LDEPFSALDEQLRRQIR-EdmIAAL-RANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPADLDAALFI 239
Cdd:PRK11650  158 FDEPLSNLDAKLRVQMRlE--IQRLhRRLKTTSLYVTHDQVEAMTLADRVVVMNGGVAEQIGTPVEVYEKPASTFVASFI 235

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1067578656 240 GEGIV--FPAALNADGTA---DCRL-GRLPVQSGAPAGTRGTLLIRPEQFSLHPHsapAASIHAVV 299
Cdd:PRK11650  236 GSPAMnlLDGRVSADGAAfelAGGIaLPLGGGYRQYAGRKLTLGIRPEHIALSSA---EGGVPLTV 298
DppF COG1124
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 4-230 1.26e-64

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440741 [Multi-domain]  Cd Length: 248  Bit Score: 205.04  E-value: 1.26e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   4 ALHIGHLSKSF----QNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsKNTNLPVRE 79
Cdd:COG1124     1 MLEVRNLSVSYgqggRRVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGRPV--TRRRRKAFR 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  80 RRLGYLVQ--EGVLFPHLTVYRNIAYGLgNGKGRTAQERqRIEAMLELTGI-SELAGRYPHELSGGQQQRVALARALAPD 156
Cdd:COG1124    79 RRVQMVFQdpYASLHPRHTVDRILAEPL-RIHGLPDREE-RIAELLEQVGLpPSFLDRYPHQLSGGQRQRVAIARALILE 156

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1067578656 157 PELILLDEPFSALDEQLRRQIReDMIAALRA-NGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQP 230
Cdd:COG1124   157 PELLLLDEPTSALDVSVQAEIL-NLLKDLREeRGLTYLFVSHDLAVVAHLCDRVAVMQNGRIVEELTVADLLAGP 230
proV TIGR01186
glycine betaine/L-proline transport ATP binding subunit; This model describes the glycine ...
 20-240 1.96e-64

glycine betaine/L-proline transport ATP binding subunit; This model describes the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Functionally, this transport system is involved in osmoregulation. Under conditions of stress, the organism recruits these transport system to accumulate glycine betaine and other solutes which offer osmo-protection. It has been demonstrated that glycine betaine uptake is accompanied by symport with sodium ions. The locus has been named variously as proU or opuA. A gene library from L.lactis functionally complements an E.coli proU mutant. The comlementing locus is similar to a opuA locus in B.sutlis. This clarifies the differences in nomenclature. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 130254 [Multi-domain]  Cd Length: 363  Bit Score: 208.55  E-value: 1.96e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  20 LNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIF--SKNTNLPVRERRLGYLVQEGVLFPHLTV 97
Cdd:TIGR01186   9 VNDADLAIAKGEIFVIMGLSGSGKSTTVRMLNRLIEPTAGQIFIDGENIMkqSPVELREVRRKKIGMVFQQFALFPHMTI 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  98 YRNIAYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDEQLRRQI 177
Cdd:TIGR01186  89 LQNTSLGPELLGWPEQERKEKALELLKLVGLEEYEHRYPDELSGGMQQRVGLARALAAEPDILLMDEAFSALDPLIRDSM 168

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1067578656 178 REDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPADLDAALFIG 240
Cdd:TIGR01186 169 QDELKKLQATLQKTIVFITHDLDEAIRIGDRIVIMKAGEIVQVGTPDEILRNPANEYVEEFIG 231
ABC_NikE_OppD_transporters cd03257
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...
 5-217 3.31e-64

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.


Pssm-ID: 213224 [Multi-domain]  Cd Length: 228  Bit Score: 203.51  E-value: 3.31e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQN----TPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNTN-LPVRE 79
Cdd:cd03257     2 LEVKNLSVSFPTgggsVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKLSRRlRKIRR 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  80 RRLGYLVQE--GVLFPHLTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGI---SELAGRYPHELSGGQQQRVALARALA 154
Cdd:cd03257    82 KEIQMVFQDpmSSLNPRMTIGEQIAEPLRIHGKLSKKEARKEAVLLLLVGVglpEEVLNRYPHELSGGQRQRVAIARALA 161

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1067578656 155 PDPELILLDEPFSALDEQLRRQIrEDMIAALRA-NGKSAVFVSHDREEALQYADRIAVMKQGRI 217
Cdd:cd03257   162 LNPKLLIADEPTSALDVSVQAQI-LDLLKKLQEeLGLTLLFITHDLGVVAKIADRVAVMYAGKI 224
ABC_DR_subfamily_A cd03230
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...
 5-217 1.09e-63

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213197 [Multi-domain]  Cd Length: 173  Bit Score: 199.93  E-value: 1.09e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNTNLPvreRRLGY 84
Cdd:cd03230     1 IEVRNLSKRYGKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIKKEPEEVK---RRIGY 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  85 LVQEGVLFPHLTVYRNIayglgngkgrtaqerqrieamleltgiselagryphELSGGQQQRVALARALAPDPELILLDE 164
Cdd:cd03230    78 LPEEPSLYENLTVRENL------------------------------------KLSGGMKQRLALAQALLHDPELLILDE 121

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1067578656 165 PFSALDEQLRRQIREdMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRI 217
Cdd:cd03230   122 PTSGLDPESRREFWE-LLRELKKEGKTILLSSHILEEAERLCDRVAILNNGRI 173
TauB COG4525
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
3-223 2.24e-63

ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443596 [Multi-domain]  Cd Length: 262  Bit Score: 202.40  E-value: 2.24e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   3 AALHIGHLSKSF----QNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSkntnlPVR 78
Cdd:COG4525     2 SMLTVRHVSVRYpgggQPQPALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITLDGVPVTG-----PGA 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  79 ERrlGYLVQEGVLFPHLTVYRNIAYGLG-NGKGRtAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDP 157
Cdd:COG4525    77 DR--GVVFQKDALLPWLNVLDNVAFGLRlRGVPK-AERRARAEELLALVGLADFARRRIWQLSGGMRQRVGIARALAADP 153

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1067578656 158 ELILLDEPFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMK--QGRILQTASP 223
Cdd:COG4525   154 RFLLMDEPFGALDALTREQMQELLLDVWQRTGKGVFLITHSVEEALFLATRLVVMSpgPGRIVERLEL 221
ThiQ COG3840
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
5-241 3.21e-63

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];


Pssm-ID: 443051 [Multi-domain]  Cd Length: 232  Bit Score: 201.14  E-value: 3.21e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQNTPVlnDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRERRLGY 84
Cdd:COG3840     2 LRLDDLTYRYGDFPL--RFDLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQDL----TALPPAERPVSM 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  85 LVQEGVLFPHLTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDE 164
Cdd:COG3840    76 LFQENNLFPHLTVAQNIGLGLRPGLKLTAEQRAQVEQALERVGLAGLLDRLPGQLSGGQRQRVALARCLVRKRPILLLDE 155

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1067578656 165 PFSALDEQLRRQIReDMIAALRAN-GKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPADLDAALFIGE 241
Cdd:COG3840   156 PFSALDPALRQEML-DLVDELCRErGLTVLMVTHDPEDAARIADRVLLVADGRIAADGPTAALLDGEPPPALAAYLGI 232
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
 1-254 2.32e-62

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 207.06  E-value: 2.32e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   1 MTAALHIGHLSKSF--QNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPD---SGEISLSGKTIFSknTNL 75
Cdd:COG1123     1 MTPLLEVRDLSVRYpgGDVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGgriSGEVLLDGRDLLE--LSE 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  76 PVRERRLGYLVQE--GVLFPhLTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARAL 153
Cdd:COG1123    79 ALRGRRIGMVFQDpmTQLNP-VTVGDQIAEALENLGLSRAEARARVLELLEAVGLERRLDRYPHQLSGGQRQRVAIAMAL 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 154 APDPELILLDEPFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPADL 233
Cdd:COG1123   158 ALDPDLLIADEPTTALDVTTQAEILDLLRELQRERGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPEEILAAPQAL 237

                         250       260
                  ....*....|....*....|.
gi 1067578656 234 DAALFIGEGIVFPAALNADGT 254
Cdd:COG1123   238 AAVPRLGAARGRAAPAAAAAE 258
ABC_MetN_methionine_transporter cd03258
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...
 5-230 1.17e-61

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213225 [Multi-domain]  Cd Length: 233  Bit Score: 197.03  E-value: 1.17e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQNT----PVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFS-KNTNLPVRE 79
Cdd:cd03258     2 IELKNVSKVFGDTggkvTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTLlSGKELRKAR 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  80 RRLGYLVQEGVLFPHLTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPEL 159
Cdd:cd03258    82 RRIGMIFQHFNLLSSRTVFENVALPLEIAGVPKAEIEERVLELLELVGLEDKADAYPAQLSGGQKQRVGIARALANNPKV 161

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1067578656 160 ILLDEPFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQP 230
Cdd:cd03258   162 LLCDEATSALDPETTQSILALLRDINRELGLTIVLITHEMEVVKRICDRVAVMEKGEVVEEGTVEEVFANP 232
YnjD COG4136
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ...
 5-225 4.35e-61

ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];


Pssm-ID: 443311 [Multi-domain]  Cd Length: 211  Bit Score: 194.62  E-value: 4.35e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPD---SGEISLSGKTIfsknTNLPVRERR 81
Cdd:COG4136     2 LSLENLTITLGGRPLLAPLSLTVAPGEILTLMGPSGSGKSTLLAAIAGTLSPAfsaSGEVLLNGRRL----TALPAEQRR 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  82 LGYLVQEGVLFPHLTVYRNIAYGLGNGKGRtAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELIL 161
Cdd:COG4136    78 IGILFQDDLLFPHLSVGENLAFALPPTIGR-AQRRARVEQALEEAGLAGFADRDPATLSGGQRARVALLRALLAEPRALL 156

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1067578656 162 LDEPFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQyadriavmkQGRILQTASPHE 225
Cdd:COG4136   157 LDEPFSKLDAALRAQFREFVFEQIRQRGIPALLVTHDEEDAPA---------AGRVLDLGNWQH 211
PhnC COG3638
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ...
 3-238 5.16e-61

ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 442855 [Multi-domain]  Cd Length: 249  Bit Score: 196.05  E-value: 5.16e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   3 AALHIGHLSKSFQN-TPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRE-- 79
Cdd:COG3638     1 PMLELRNLSKRYPGgTPALDDVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVEPTSGEILVDGQDV----TALRGRAlr 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  80 ---RRLGYLVQEGVLFPHLTVYRNIAYGLGNGKGR--------TAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVA 148
Cdd:COG3638    77 rlrRRIGMIFQQFNLVPRLSVLTNVLAGRLGRTSTwrsllglfPPEDRERALEALERVGLADKAYQRADQLSGGQQQRVA 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 149 LARALAPDPELILLDEPFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILqtaspheLYR 228
Cdd:COG3638   157 IARALVQEPKLILADEPVASLDPKTARQVMDLLRRIAREDGITVVVNLHQVDLARRYADRIIGLRDGRVV-------FDG 229

                         250
                  ....*....|
gi 1067578656 229 QPADLDAALF 238
Cdd:COG3638   230 PPAELTDAVL 239
modC_ABC TIGR02142
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ...
 22-295 1.01e-59

molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]


Pssm-ID: 131197 [Multi-domain]  Cd Length: 354  Bit Score: 196.10  E-value: 1.01e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  22 DISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFS--KNTNLPVRERRLGYLVQEGVLFPHLTVYR 99
Cdd:TIGR02142  15 DADFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTRPDEGEIVLNGRTLFDsrKGIFLPPEKRRIGYVFQEARLFPHLSVRG 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 100 NIAYGLGngKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDEQLRRQIRE 179
Cdd:TIGR02142  95 NLRYGMK--RARPSERRISFERVIELLGIGHLLGRLPGRLSGGEKQRVAIGRALLSSPRLLLMDEPLAALDDPRKYEILP 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 180 DMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPaDLDAALFIGEGIVFPAAL----NADGTA 255
Cdd:TIGR02142 173 YLERLHAEFGIPILYVSHSLQEVLRLADRVVVLEDGRVAAAGPIAEVWASP-DLPWLAREDQGSLIEGVVaehdQHYGLT 251

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 1067578656 256 DCRL--GRLPV-QSGAPAGTRGTLLIRPEQFSLHPHSAPAASI 295
Cdd:TIGR02142 252 ALRLggGHLWVpENLGPTGARLRLRVPARDVSLALQKPEATSI 294
FtsE COG2884
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
9-217 1.62e-59

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442130 [Multi-domain]  Cd Length: 223  Bit Score: 191.03  E-value: 1.62e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   9 HLSKSFQN-TPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRE-----RRL 82
Cdd:COG2884     6 NVSKRYPGgREALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDL----SRLKRREipylrRRI 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  83 GYLVQEGVLFPHLTVYRNIAYGLG-NGKGRtAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELIL 161
Cdd:COG2884    82 GVVFQDFRLLPDRTVYENVALPLRvTGKSR-KEIRRRVREVLDLVGLSDKAKALPHELSGGEQQRVAIARALVNRPELLL 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1067578656 162 LDEPFSALDEQLRRQIREdMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRI 217
Cdd:COG2884   161 ADEPTGNLDPETSWEIME-LLEEINRRGTTVLIATHDLELVDRMPKRVLELEDGRL 215
glnQ PRK09493
glutamine ABC transporter ATP-binding protein GlnQ;
11-230 2.13e-59

glutamine ABC transporter ATP-binding protein GlnQ;


Pssm-ID: 181906 [Multi-domain]  Cd Length: 240  Bit Score: 191.46  E-value: 2.13e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  11 SKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNTNlpVRERRL--GYLVQE 88
Cdd:PRK09493    8 SKHFGPTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKVNDPKVD--ERLIRQeaGMVFQQ 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  89 GVLFPHLTVYRNIAYGLGNGKGRTAQE-RQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFS 167
Cdd:PRK09493   86 FYLFPHLTALENVMFGPLRVRGASKEEaEKQARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKPKLMLFDEPTS 165

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1067578656 168 ALDEQLRRQIREDMiAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQP 230
Cdd:PRK09493  166 ALDPELRHEVLKVM-QDLAEEGMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDGDPQVLIKNP 227
PRK11000 PRK11000
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
11-314 1.07e-58

maltose/maltodextrin ABC transporter ATP-binding protein MalK;


Pssm-ID: 182893 [Multi-domain]  Cd Length: 369  Bit Score: 193.71  E-value: 1.07e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  11 SKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRERRLGYLVQEGV 90
Cdd:PRK11000   10 TKAYGDVVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKRM----NDVPPAERGVGMVFQSYA 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  91 LFPHLTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALD 170
Cdd:PRK11000   86 LYPHLSVAENMSFGLKLAGAKKEEINQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVFLLDEPLSNLD 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 171 EQLRRQIREDmIAAL-RANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPADLDAALFIGEG-----IV 244
Cdd:PRK11000  166 AALRVQMRIE-ISRLhKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKPLELYHYPANRFVAGFIGSPkmnflPV 244

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1067578656 245 FPAALNADG----TADCRLGRLPVQS-GAPAGTRGTLLIRPEQfsLHPHSAPAASIHAVVLKTTPKARHTEISLR 314
Cdd:PRK11000  245 KVTATAIEQvqveLPNRQQVWLPVEGrGVQVGANMSLGIRPEH--LLPSDIADVTLEGEVQVVEQLGNETQIHIQ 317
FetA COG4619
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
5-217 6.35e-58

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443661 [Multi-domain]  Cd Length: 209  Bit Score: 186.56  E-value: 6.35e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRE--RRL 82
Cdd:COG4619     1 LELEGLSFRVGGKPILSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPL----SAMPPPEwrRQV 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  83 GYLVQEGVLFPHlTVYRNIAYGLGNGKGRTaqERQRIEAMLELTGISE-LAGRYPHELSGGQQQRVALARALAPDPELIL 161
Cdd:COG4619    77 AYVPQEPALWGG-TVRDNLPFPFQLRERKF--DRERALELLERLGLPPdILDKPVERLSGGERQRLALIRALLLQPDVLL 153

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1067578656 162 LDEPFSALDEQLRRQIrEDMIAALRAN-GKSAVFVSHDREEALQYADRIAVMKQGRI 217
Cdd:COG4619   154 LDEPTSALDPENTRRV-EELLREYLAEeGRAVLWVSHDPEQIERVADRVLTLEAGRL 209
ABC_Mj1267_LivG_branched cd03219
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...
 5-231 1.03e-57

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).


Pssm-ID: 213186 [Multi-domain]  Cd Length: 236  Bit Score: 186.87  E-value: 1.03e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRER-RLG 83
Cdd:cd03219     1 LEVRGLTKRFGGLVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEDI----TGLPPHEIaRLG 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  84 yLV---QEGVLFPHLTVYRNIAYGLGNGKGRT----------AQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALA 150
Cdd:cd03219    77 -IGrtfQIPRLFPELTVLENVMVAAQARTGSGlllararreeREARERAEELLERVGLADLADRPAGELSYGQQRRLEIA 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 151 RALAPDPELILLDEPFSALDEQLRRQIREdMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQP 230
Cdd:cd03219   156 RALATDPKLLLLDEPAAGLNPEETEELAE-LIRELRERGITVLLVEHDMDVVMSLADRVTVLDQGRVIAEGTPDEVRNNP 234


                  .
gi 1067578656 231 A 231
Cdd:cd03219   235 R 235
ABC_choXWV_ATP TIGR03415
choline ABC transporter, ATP-binding protein; Members of this protein family are the ...
 21-239 3.58e-57

choline ABC transporter, ATP-binding protein; Members of this protein family are the ATP-binding subunit of a three-protein transporter. This family belongs, more broadly, to the family of proline and glycine-betaine transporters, but members have been identified by direct characterization and by bioinformatic means as choline transporters. Many species have several closely-related members of this family, probably with variable abilities to act additionally on related quaternary amines. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 188317 [Multi-domain]  Cd Length: 382  Bit Score: 190.37  E-value: 3.58e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  21 NDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNTNLPV------RERRLGYLVQEGVLFPH 94
Cdd:TIGR03415  41 HNASLDIEEGEICVLMGLSGSGKSTLLRAVNGLNPVSRGSVLVKDGDGSVDVANCDAatlrrlRTHRVSMVFQQFALLPW 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  95 LTVYRNIAYGL---GNGKgrtAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDE 171
Cdd:TIGR03415 121 RTVEENVAFGLemqGMPK---AERRKRVDEQLELVGLAQWADRKPGELSGGMQQRVGLARAFATEAPILLMDEPFSALDP 197

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1067578656 172 QLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPADLDAALFI 239
Cdd:TIGR03415 198 LIRTQLQDELLELQSKLKKTIVFVSHDLDEALKIGNRIAIMEGGRIIQHGTPEEIVLNPANDYVADFV 265
DppD COG0444
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 5-231 1.18e-56

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440213 [Multi-domain]  Cd Length: 320  Bit Score: 186.80  E-value: 1.18e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQ----NTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQP---DSGEISLSGKTI--FSKNTNL 75
Cdd:COG0444     2 LEVRNLKVYFPtrrgVVKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPPpgiTSGEILFDGEDLlkLSEKELR 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  76 PVRERRLGYLVQE--GVLFPHLTVYRNIAYGLGNGKGRTAQE-RQRIEAMLELTGIS---ELAGRYPHELSGGQQQRVAL 149
Cdd:COG0444    82 KIRGREIQMIFQDpmTSLNPVMTVGDQIAEPLRIHGGLSKAEaRERAIELLERVGLPdpeRRLDRYPHELSGGMRQRVMI 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 150 ARALAPDPELILLDEPFSALDEQLRRQIrEDMIAALRAN-GKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYR 228
Cdd:COG0444   162 ARALALEPKLLIADEPTTALDVTIQAQI-LNLLKDLQRElGLAILFITHDLGVVAEIADRVAVMYAGRIVEEGPVEELFE 240


                  ...
gi 1067578656 229 QPA 231
Cdd:COG0444   241 NPR 243
ABC_Metallic_Cations cd03235
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...
 9-215 2.47e-56

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.


Pssm-ID: 213202 [Multi-domain]  Cd Length: 213  Bit Score: 182.73  E-value: 2.47e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   9 HLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNtnlpvreRRLGYLVQE 88
Cdd:cd03235     4 DLTVSYGGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGKPLEKER-------KRIGYVPQR 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  89 GVL---FPhLTVYRNIAYGL----GNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELIL 161
Cdd:cd03235    77 RSIdrdFP-ISVRDVVLMGLyghkGLFRRLSKADKAKVDEALERVGLSELADRQIGELSGGQQQRVLLARALVQDPDLLL 155

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1067578656 162 LDEPFSALDEQLRRQIREdMIAALRANGKSAVFVSHDREEALQYADRIAVMKQG 215
Cdd:cd03235   156 LDEPFAGVDPKTQEDIYE-LLRELRREGMTILVVTHDLGLVLEYFDRVLLLNRT 208
ABC_Iron-Siderophores_B12_Hemin cd03214
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...
 9-218 5.01e-56

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.


Pssm-ID: 213181 [Multi-domain]  Cd Length: 180  Bit Score: 180.71  E-value: 5.01e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   9 HLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRE--RRLGYLV 86
Cdd:cd03214     4 NLSVGYGGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDL----ASLSPKElaRKIAYVP 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  87 QegvlfphltvyrniayglgngkgrtaqerqrieaMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPF 166
Cdd:cd03214    80 Q----------------------------------ALELLGLAHLADRPFNELSGGERQRVLLARALAQEPPILLLDEPT 125

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1067578656 167 SALDeqLRRQIR-EDMIAAL-RANGKSAVFVSHDREEALQYADRIAVMKQGRIL 218
Cdd:cd03214   126 SHLD--IAHQIElLELLRRLaRERGKTVVMVLHDLNLAARYADRVILLKDGRIV 177
ABC_PstB_phosphate_transporter cd03260
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...
 10-226 9.87e-56

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).


Pssm-ID: 213227 [Multi-domain]  Cd Length: 227  Bit Score: 181.61  E-value: 9.87e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  10 LSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGF-----EQPDSGEISLSGKTIFSKNTNLPVRERRLGY 84
Cdd:cd03260     6 LNVYYGDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLndlipGAPDEGEVLLDGKDIYDLDVDVLELRRRVGM 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  85 LVQEGVLFPhLTVYRNIAYGLG-NGKGRTAQERQRIEAMLELTGISELAGR--YPHELSGGQQQRVALARALAPDPELIL 161
Cdd:cd03260    86 VFQKPNPFP-GSIYDNVAYGLRlHGIKLKEELDERVEEALRKAALWDEVKDrlHALGLSGGQQQRLCLARALANEPEVLL 164

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1067578656 162 LDEPFSALDEQLRRQIrEDMIAALRANgKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHEL 226
Cdd:cd03260   165 LDEPTSALDPISTAKI-EELIAELKKE-YTIVIVTHNMQQAARVADRTAFLLNGRLVEFGPTEQI 227
AbcC COG1135
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
9-230 1.25e-55

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440750 [Multi-domain]  Cd Length: 339  Bit Score: 184.90  E-value: 1.25e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   9 HLSKSF----QNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRE----- 79
Cdd:COG1135     6 NLSKTFptkgGPVTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGVDL----TALSERElraar 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  80 RRLGYLVQEGVLFPHLTVYRNIAYGL-GNGKGRtAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPE 158
Cdd:COG1135    82 RKIGMIFQHFNLLSSRTVAENVALPLeIAGVPK-AEIRKRVAELLELVGLSDKADAYPSQLSGGQKQRVGIARALANNPK 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1067578656 159 LILLDEPFSALDEQ-------LRRQIREDMiaalranGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQP 230
Cdd:COG1135   161 VLLCDEATSALDPEttrsildLLKDINREL-------GLTIVLITHEMDVVRRICDRVAVLENGRIVEQGPVLDVFANP 232
ECF_ATPase_2 TIGR04521
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
 9-233 1.36e-55

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275314 [Multi-domain]  Cd Length: 277  Bit Score: 182.65  E-value: 1.36e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   9 HLSKSFQ-NTP----VLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKN-TNL-PVReRR 81
Cdd:TIGR04521   5 NVSYIYQpGTPfekkALDDVSLTIEDGEFVAIIGHTGSGKSTLIQHLNGLLKPTSGTVTIDGRDITAKKkKKLkDLR-KK 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  82 LGYLVQ--EGVLFpHLTVYRNIAYGLGNgKGRTAQE-RQRIEAMLELTGISE-LAGRYPHELSGGQQQRVALARALAPDP 157
Cdd:TIGR04521  84 VGLVFQfpEHQLF-EETVYKDIAFGPKN-LGLSEEEaEERVKEALELVGLDEeYLERSPFELSGGQMRRVAIAGVLAMEP 161

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1067578656 158 ELILLDEPFSALDEQLRRQIReDMIAAL-RANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPADL 233
Cdd:TIGR04521 162 EVLILDEPTAGLDPKGRKEIL-DLFKRLhKEKGLTVILVTHSMEDVAEYADRVIVMHKGKIVLDGTPREVFSDVDEL 237
ABC_PhnC_transporter cd03256
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ...
 5-226 2.20e-54

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213223 [Multi-domain]  Cd Length: 241  Bit Score: 178.53  E-value: 2.20e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQN-TPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRE---- 79
Cdd:cd03256     1 IEVENLSKTYPNgKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDI----NKLKGKAlrql 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  80 -RRLGYLVQEGVLFPHLTVYRNIAYG-LGN-GKGR------TAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALA 150
Cdd:cd03256    77 rRQIGMIFQQFNLIERLSVLENVLSGrLGRrSTWRslfglfPKEEKQRALAALERVGLLDKAYQRADQLSGGQQQRVAIA 156

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1067578656 151 RALAPDPELILLDEPFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHEL 226
Cdd:cd03256   157 RALMQQPKLILADEPVASLDPASSRQVMDLLKRINREEGITVIVSLHQVDLAREYADRIVGLKDGRIVFDGPPAEL 232
LivG COG0411
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ...
 1-231 8.09e-54

ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];


Pssm-ID: 440180 [Multi-domain]  Cd Length: 257  Bit Score: 177.54  E-value: 8.09e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   1 MTAALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRER 80
Cdd:COG0411     1 SDPLLEVRGLTKRFGGLVAVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFDGRDI----TGLPPHRI 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  81 -RLGyLV---QEGVLFPHLTVYRNIAYGLGNGKGRT---------------AQERQRIEAMLELTGISELAGRYPHELSG 141
Cdd:COG0411    77 aRLG-IArtfQNPRLFPELTVLENVLVAAHARLGRGllaallrlprarreeREARERAEELLERVGLADRADEPAGNLSY 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 142 GQQQRVALARALAPDPELILLDEPFSALDEQLRRQIReDMIAALRAN-GKSAVFVSHDREEALQYADRIAVMKQGRILQT 220
Cdd:COG0411   156 GQQRRLEIARALATEPKLLLLDEPAAGLNPEETEELA-ELIRRLRDErGITILLIEHDMDLVMGLADRIVVLDFGRVIAE 234

                         250
                  ....*....|.
gi 1067578656 221 ASPHELYRQPA 231
Cdd:COG0411   235 GTPAEVRADPR 245
ABC_subfamily_A cd03263
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...
 5-226 2.72e-52

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.


Pssm-ID: 213230 [Multi-domain]  Cd Length: 220  Bit Score: 172.30  E-value: 2.72e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQN--TPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGktiFSKNTNLPVRERRL 82
Cdd:cd03263     1 LQIRNLTKTYKKgtKPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYING---YSIRTDRKAARQSL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  83 GYLVQEGVLFPHLTVYRNIA-YGLGNGKGRTaQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELIL 161
Cdd:cd03263    78 GYCPQFDALFDELTVREHLRfYARLKGLPKS-EIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPSVLL 156

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1067578656 162 LDEPFSALDEQLRRQIReDMIAALRANgKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHEL 226
Cdd:cd03263   157 LDEPTSGLDPASRRAIW-DLILEVRKG-RSIILTTHSMDEAEALCDRIAIMSDGKLRCIGSPQEL 219
AppF COG4608
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ...
 20-231 1.36e-51

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443658 [Multi-domain]  Cd Length: 329  Bit Score: 174.15  E-value: 1.36e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  20 LNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIF--SKNTNLPVReRRLGYLVQE--GVLFPHL 95
Cdd:COG4608    34 VDGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEILFDGQDITglSGRELRPLR-RRMQMVFQDpyASLNPRM 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  96 TVYRNIAYGLG-NGKGRTAQERQRIEAMLELTGIS-ELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDEQL 173
Cdd:COG4608   113 TVGDIIAEPLRiHGLASKAERRERVAELLELVGLRpEHADRYPHEFSGGQRQRIGIARALALNPKLIVCDEPVSALDVSI 192

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1067578656 174 RRQI-------REDMiaalranGKSAVFVSHD----ReealQYADRIAVMKQGRILQTASPHELYRQPA 231
Cdd:COG4608   193 QAQVlnlledlQDEL-------GLTYLFISHDlsvvR----HISDRVAVMYLGKIVEIAPRDELYARPL 250
CcmA COG4133
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ...
 3-202 1.84e-51

ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443308 [Multi-domain]  Cd Length: 206  Bit Score: 169.97  E-value: 1.84e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   3 AALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfskNTNLPVRERRL 82
Cdd:COG4133     1 MMLEAENLSCRRGERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPI---RDAREDYRRRL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  83 GYLVQEGVLFPHLTVYRNIAYGLGNGKGRTAQErqRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILL 162
Cdd:COG4133    78 AYLGHADGLKPELTVRENLRFWAALYGLRADRE--AIDEALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSPAPLWLL 155

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1067578656 163 DEPFSALDEQLRRQIrEDMIAALRANGKSAVFVSHDREEA 202
Cdd:COG4133   156 DEPFTALDAAGVALL-AELIAAHLARGGAVLLTTHQPLEL 194
COG4559 COG4559
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
5-225 2.23e-51

ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443620 [Multi-domain]  Cd Length: 258  Bit Score: 171.45  E-value: 2.23e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRE--RRL 82
Cdd:COG4559     2 LEAENLSVRLGGRTLLDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPSSGEVRLNGRPL----AAWSPWElaRRR 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  83 GYLVQEGVL-FPhLTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALA------- 154
Cdd:COG4559    78 AVLPQHSSLaFP-FTVEEVVALGRAPHGSSAAQDRQIVREALALVGLAHLAGRSYQTLSGGEQQRVQLARVLAqlwepvd 156

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1067578656 155 PDPELILLDEPFSALDeqLRRQIREDMIAALRANGKSAVF-VSHDREEALQYADRIAVMKQGRILQTASPHE 225
Cdd:COG4559   157 GGPRWLFLDEPTSALD--LAHQHAVLRLARQLARRGGGVVaVLHDLNLAAQYADRILLLHQGRLVAQGTPEE 226
fecE PRK11231
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
5-238 4.50e-51

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;


Pssm-ID: 183044 [Multi-domain]  Cd Length: 255  Bit Score: 170.58  E-value: 4.50e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRE--RRL 82
Cdd:PRK11231    3 LRTENLTVGYGTKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPI----SMLSSRQlaRRL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  83 GYLVQ-----EGVlfphlTVYRNIAYGLG---NGKGRTAQE-RQRIEAMLELTGISELAGRYPHELSGGQQQRVALARAL 153
Cdd:PRK11231   79 ALLPQhhltpEGI-----TVRELVAYGRSpwlSLWGRLSAEdNARVNQAMEQTRINHLADRRLTDLSGGQRQRAFLAMVL 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 154 APDPELILLDEPFSALDeqLRRQIR-EDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHE-----LY 227
Cdd:PRK11231  154 AQDTPVVLLDEPTTYLD--INHQVElMRLMRELNTQGKTVVTVLHDLNQASRYCDHLVVLANGHVMAQGTPEEvmtpgLL 231

                         250
                  ....*....|.
gi 1067578656 228 RQPADLDAALF 238
Cdd:PRK11231  232 RTVFDVEAEIH 242
YhaQ COG4152
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 4-229 5.06e-51

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443322 [Multi-domain]  Cd Length: 298  Bit Score: 171.83  E-value: 5.06e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   4 ALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfskntNLPVReRRLG 83
Cdd:COG4152     1 MLELKGLTKRFGDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGEPL-----DPEDR-RRIG 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  84 YLVQEGVLFPHLTVYRNIAYgLGNGKGRTAQE-RQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILL 162
Cdd:COG4152    75 YLPEERGLYPKMKVGEQLVY-LARLKGLSKAEaKRRADEWLERLGLGDRANKKVEELSKGNQQKVQLIAALLHDPELLIL 153

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1067578656 163 DEPFSALD----EQLRRQIREdmiaaLRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQ 229
Cdd:COG4152   154 DEPFSGLDpvnvELLKDVIRE-----LAAKGTTVIFSSHQMELVEELCDRIVIINKGRKVLSGSVDEIRRQ 219
tauB PRK11248
taurine ABC transporter ATP-binding subunit;
4-223 9.76e-51

taurine ABC transporter ATP-binding subunit;


Pssm-ID: 183056 [Multi-domain]  Cd Length: 255  Bit Score: 169.50  E-value: 9.76e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   4 ALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfskntNLPVRERrlG 83
Cdd:PRK11248    1 MLQISHLYADYGGKPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKPV-----EGPGAER--G 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  84 YLVQEGVLFPHLTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLD 163
Cdd:PRK11248   74 VVFQNEGLLPWRNVQDNVAFGLQLAGVEKMQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLD 153

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1067578656 164 EPFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMK--QGRILQTASP 223
Cdd:PRK11248  154 EPFGALDAFTREQMQTLLLKLWQETGKQVLLITHDIEEAVFMATELVLLSpgPGRVVERLPL 215
hmuV PRK13548
hemin importer ATP-binding subunit; Provisional
 3-225 9.79e-51

hemin importer ATP-binding subunit; Provisional


Pssm-ID: 237422 [Multi-domain]  Cd Length: 258  Bit Score: 169.57  E-value: 9.79e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   3 AALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRE--R 80
Cdd:PRK13548    1 AMLEARNLSVRLGGRTLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPL----ADWSPAElaR 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  81 RLGYLVQEGVL-FPhLTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALA----- 154
Cdd:PRK13548   77 RRAVLPQHSSLsFP-FTVEEVVAMGRAPHGLSRAEDDALVAAALAQVDLAHLAGRDYPQLSGGEQQRVQLARVLAqlwep 155

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1067578656 155 -PDPELILLDEPFSALDeqLRRQIREDMIAALRA--NGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHE 225
Cdd:PRK13548  156 dGPPRWLLLDEPTSALD--LAHQHHVLRLARQLAheRGLAVIVVLHDLNLAARYADRIVLLHQGRLVADGTPAE 227
L_ocin_972_ABC TIGR03608
putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly ...
 9-209 1.70e-50

putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly wide distribution consists of a polypeptide related to the lactococcin 972 (see TIGR01653) and multiple-membrane-spanning putative immunity protein (see TIGR01654). This model represents a small clade within the ABC transporters that regularly are found adjacent to these bacteriocin system gene pairs and are likely serve as export proteins. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]


Pssm-ID: 188353 [Multi-domain]  Cd Length: 206  Bit Score: 167.41  E-value: 1.70e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   9 HLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNTNLPVRERR--LGYLV 86
Cdd:TIGR03608   3 NISKKFGDKVILDDLNLTIEKGKMYAIIGESGSGKSTLLNIIGLLEKFDSGQVYLNGQETPPLNSKKASKFRRekLGYLF 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  87 QEGVLFPHLTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPF 166
Cdd:TIGR03608  83 QNFALIENETVEENLDLGLKYKKLSKKEKREKKKEALEKVGLNLKLKQKIYELSGGEQQRVALARAILKPPPLILADEPT 162

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1067578656 167 SALDEQLRRQIReDMIAALRANGKSAVFVSHDREEALQyADRI 209
Cdd:TIGR03608 163 GSLDPKNRDEVL-DLLLELNDEGKTIIIVTHDPEVAKQ-ADRV 203
ABC_ThiQ_thiamine_transporter cd03298
ATP-binding cassette domain of the thiamine transport system; Part of the ...
 13-217 2.76e-50

ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213265 [Multi-domain]  Cd Length: 211  Bit Score: 166.90  E-value: 2.76e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  13 SFQNTPVlnDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRERRLGYLVQEGVLF 92
Cdd:cd03298     9 SYGEQPM--HFDLTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVDV----TAAPPADRPVSMLFQENNLF 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  93 PHLTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDEQ 172
Cdd:cd03298    83 AHLTVEQNVGLGLSPGLKLTAEDRQAIEVALARVGLAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAALDPA 162

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1067578656 173 LRRQIrEDMIAALRANGKSAV-FVSHDREEALQYADRIAVMKQGRI 217
Cdd:cd03298   163 LRAEM-LDLVLDLHAETKMTVlMVTHQPEDAKRLAQRVVFLDNGRI 207
HisP COG4598
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];
2-230 4.70e-50

ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443652 [Multi-domain]  Cd Length: 259  Bit Score: 168.06  E-value: 4.70e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   2 TAALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTI---FSKNTNLPVR 78
Cdd:COG4598     6 PPALEVRDLHKSFGDLEVLKGVSLTARKGDVISIIGSSGSGKSTFLRCINLLETPDSGEIRVGGEEIrlkPDRDGELVPA 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  79 ER--------RLGYLVQEGVLFPHLTVYRNIAYG----LGNGKgrtAQERQRIEAMLELTGISELAGRYPHELSGGQQQR 146
Cdd:COG4598    86 DRrqlqrirtRLGMVFQSFNLWSHMTVLENVIEApvhvLGRPK---AEAIERAEALLAKVGLADKRDAYPAHLSGGQQQR 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 147 VALARALAPDPELILLDEPFSALD-----EQLRrqiredMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTA 221
Cdd:COG4598   163 AAIARALAMEPEVMLFDEPTSALDpelvgEVLK------VMRDLAEEGRTMLVVTHEMGFARDVSSHVVFLHQGRIEEQG 236


                  ....*....
gi 1067578656 222 SPHELYRQP 230
Cdd:COG4598   237 PPAEVFGNP 245
ABC_phnC TIGR02315
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ...
 5-227 5.06e-50

phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]


Pssm-ID: 131368 [Multi-domain]  Cd Length: 243  Bit Score: 167.48  E-value: 5.06e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQN-TPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRE---- 79
Cdd:TIGR02315   2 LEVENLSKVYPNgKQALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLVEPSSGSILLEGTDI----TKLRGKKlrkl 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  80 -RRLGYLVQEGVLFPHLTVYRNIAYGLGNGKGR--------TAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALA 150
Cdd:TIGR02315  78 rRRIGMIFQHYNLIERLTVLENVLHGRLGYKPTwrsllgrfSEEDKERALSALERVGLADKAYQRADQLSGGQQQRVAIA 157

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1067578656 151 RALAPDPELILLDEPFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELY 227
Cdd:TIGR02315 158 RALAQQPDLILADEPIASLDPKTSKQVMDYLKRINKEDGITVIINLHQVDLAKKYADRIVGLKAGEIVFDGAPSELD 234
SunT COG2274
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...
 15-226 1.10e-49

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];


Pssm-ID: 441875 [Multi-domain]  Cd Length: 711  Bit Score: 176.56  E-value: 1.10e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  15 QNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsKNTNLPVRERRLGYLVQEGVLFpH 94
Cdd:COG2274   486 DSPPVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDGIDL--RQIDPASLRRQIGVVLQDVFLF-S 562

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  95 LTVYRNIAYglgngkGRTAQERQRIEAMLELTGISELAGRYPH-----------ELSGGQQQRVALARALAPDPELILLD 163
Cdd:COG2274   563 GTIRENITL------GDPDATDEEIIEAARLAGLHDFIEALPMgydtvvgeggsNLSGGQRQRLAIARALLRNPRILILD 636

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1067578656 164 EPFSALDEQLRRQIredmIAALR--ANGKSAVFVSHdREEALQYADRIAVMKQGRILQTASPHEL 226
Cdd:COG2274   637 EATSALDAETEAII----LENLRrlLKGRTVIIIAH-RLSTIRLADRIIVLDKGRIVEDGTHEEL 696
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 20-167 1.17e-49

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 163.20  E-value: 1.17e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  20 LNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKntNLPVRERRLGYLVQEGVLFPHLTVYR 99
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDD--ERKSLRKEIGYVFQDPQLFPRLTVRE 78

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1067578656 100 NIAYGLGNGKGRTAQERQRIEAMLELTGISELA----GRYPHELSGGQQQRVALARALAPDPELILLDEPFS 167
Cdd:pfam00005  79 NLRLGLLLKGLSKREKDARAEEALEKLGLGDLAdrpvGERPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
ABC_YhbG cd03218
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...
 9-231 2.42e-49

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.


Pssm-ID: 213185 [Multi-domain]  Cd Length: 232  Bit Score: 165.41  E-value: 2.42e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   9 HLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRERR---LGYL 85
Cdd:cd03218     5 NLSKRYGKRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDI----TKLPMHKRArlgIGYL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  86 VQEGVLFPHLTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEP 165
Cdd:cd03218    81 PQEASIFRKLTVEENILAVLEIRGLSKKEREEKLEELLEEFHITHLRKSKASSLSGGERRRVEIARALATNPKFLLLDEP 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1067578656 166 FSALDEQLRRQIREdMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPA 231
Cdd:cd03218   161 FAGVDPIAVQDIQK-IIKILKDRGIGVLITDHNVRETLSITDRAYIIYEGKVLAEGTPEEIAANEL 225
ABC_ATPase cd00267
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...
 9-216 4.92e-49

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213179 [Multi-domain]  Cd Length: 157  Bit Score: 162.03  E-value: 4.92e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   9 HLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNtnLPVRERRLGYLVQe 88
Cdd:cd00267     4 NLSFRYGGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKLP--LEELRRRIGYVPQ- 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  89 gvlfphltvyrniayglgngkgrtaqerqrieamleltgiselagrypheLSGGQQQRVALARALAPDPELILLDEPFSA 168
Cdd:cd00267    81 --------------------------------------------------LSGGQRQRVALARALLLNPDLLLLDEPTSG 110

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1067578656 169 LDEQLRRQIREdMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGR 216
Cdd:cd00267   111 LDPASRERLLE-LLRELAEEGRTVIIVTHDPELAELAADRVIVLKDGK 157
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
1-226 1.20e-48

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 170.58  E-value: 1.20e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   1 MTAALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNtnlPVRER 80
Cdd:COG1129     1 AEPLLEMRGISKSFGGVKALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGEPVRFRS---PRDAQ 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  81 RLG-YLV-QEGVLFPHLTVYRNIAygLGNGKGR-----TAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARAL 153
Cdd:COG1129    78 AAGiAIIhQELNLVPNLSVAENIF--LGREPRRgglidWRAMRRRARELLARLGLDIDPDTPVGDLSVAQQQLVEIARAL 155

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1067578656 154 APDPELILLDEPFSALD----EQLRRQIREdmiaaLRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHEL 226
Cdd:COG1129   156 SRDARVLILDEPTASLTerevERLFRIIRR-----LKAQGVAIIYISHRLDEVFEIADRVTVLRDGRLVGTGPVAEL 227
thiQ PRK10771
thiamine ABC transporter ATP-binding protein ThiQ;
24-239 1.12e-47

thiamine ABC transporter ATP-binding protein ThiQ;


Pssm-ID: 182716 [Multi-domain]  Cd Length: 232  Bit Score: 160.90  E-value: 1.12e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  24 SLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTifskNTNLPVRERRLGYLVQEGVLFPHLTVYRNIAY 103
Cdd:PRK10771   19 DLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQD----HTTTPPSRRPVSMLFQENNLFSHLTVAQNIGL 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 104 GLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDEQLRRQIREDMIA 183
Cdd:PRK10771   95 GLNPGLKLNAAQREKLHAIARQMGIEDLLARLPGQLSGGQRQRVALARCLVREQPILLLDEPFSALDPALRQEMLTLVSQ 174

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1067578656 184 ALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPADLDAALFI 239
Cdd:PRK10771  175 VCQERQLTLLMVSHSLEDAARIAPRSLVVADGRIAWDGPTDELLSGKASASALLGI 230
PRK11264 PRK11264
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
 3-230 1.19e-47

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional


Pssm-ID: 183063 [Multi-domain]  Cd Length: 250  Bit Score: 161.46  E-value: 1.19e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   3 AALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTI-----FSKNTNLpV 77
Cdd:PRK11264    2 SAIEVKNLVKKFHGQTVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIRVGDITIdtarsLSQQKGL-I 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  78 RERR--LGYLVQEGVLFPHLTVYRNIAYGLGNGKGRTAQER-QRIEAMLELTGISELAGRYPHELSGGQQQRVALARALA 154
Cdd:PRK11264   81 RQLRqhVGFVFQNFNLFPHRTVLENIIEGPVIVKGEPKEEAtARARELLAKVGLAGKETSYPRRLSGGQQQRVAIARALA 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1067578656 155 PDPELILLDEPFSALDEQLRRQIReDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQP 230
Cdd:PRK11264  161 MRPEVILFDEPTSALDPELVGEVL-NTIRQLAQEKRTMVIVTHEMSFARDVADRAIFMDQGRIVEQGPAKALFADP 235
ntrCD TIGR01184
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ...
 20-215 1.93e-47

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]


Pssm-ID: 130252 [Multi-domain]  Cd Length: 230  Bit Score: 160.32  E-value: 1.93e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  20 LNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfskntNLPVRERRLgyLVQEGVLFPHLTVYR 99
Cdd:TIGR01184   1 LKGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILEGKQI-----TEPGPDRMV--VFQNYSLLPWLTVRE 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 100 NIAYGLG--NGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDEQLRRQI 177
Cdd:TIGR01184  74 NIALAVDrvLPDLSKSERRAIVEEHIALVGLTEAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDALTRGNL 153

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1067578656 178 REDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQG 215
Cdd:TIGR01184 154 QEELMQIWEEHRVTVLMVTHDVDEALLLSDRVVMLTNG 191
thiQ TIGR01277
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ...
 24-219 2.12e-47

thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]


Pssm-ID: 130344 [Multi-domain]  Cd Length: 213  Bit Score: 159.64  E-value: 2.12e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  24 SLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRERRLGYLVQEGVLFPHLTVYRNIAY 103
Cdd:TIGR01277  18 DLNVADGEIVAIMGPSGAGKSTLLNLIAGFIEPASGSIKVNDQSH----TGLAPYQRPVSMLFQENNLFAHLTVRQNIGL 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 104 GLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDEQLRRQIREDMIA 183
Cdd:TIGR01277  94 GLHPGLKLNAEQQEKVVDAAQQVGIADYLDRLPEQLSGGQRQRVALARCLVRPNPILLLDEPFSALDPLLREEMLALVKQ 173

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1067578656 184 ALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQ 219
Cdd:TIGR01277 174 LCSERQRTLLMVTHHLSDARAIASQIAVVSQGKIKV 209
ABC_putative_ATPase cd03269
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...
 5-217 2.61e-47

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213236 [Multi-domain]  Cd Length: 210  Bit Score: 159.37  E-value: 2.61e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfskntnLPVRERRLGY 84
Cdd:cd03269     1 LEVENVTKRFGRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPL------DIAARNRIGY 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  85 LVQEGVLFPHLTVYRNIAYgLGNGKGRTAQE-RQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLD 163
Cdd:cd03269    75 LPEERGLYPKMKVIDQLVY-LAQLKGLKKEEaRRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPELLILD 153

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1067578656 164 EPFSALDEqLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRI 217
Cdd:cd03269   154 EPFSGLDP-VNVELLKDVIRELARAGKTVILSTHQMELVEELCDRVLLLNKGRA 206
LptB COG1137
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ...
 5-230 2.87e-47

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440752 [Multi-domain]  Cd Length: 240  Bit Score: 160.19  E-value: 2.87e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRER-RLG 83
Cdd:COG1137     4 LEAENLVKSYGKRTVVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGEDI----THLPMHKRaRLG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  84 --YLVQEGVLFPHLTVYRNIAYGL-GNGKGRTAQErQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELI 160
Cdd:COG1137    80 igYLPQEASIFRKLTVEDNILAVLeLRKLSKKERE-ERLEELLEEFGITHLRKSKAYSLSGGERRRVEIARALATNPKFI 158

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1067578656 161 LLDEPFSALD----EQLRRqiredMIAALRANGKSaVFVS-HDREEALQYADRIAVMKQGRILQTASPHELYRQP 230
Cdd:COG1137   159 LLDEPFAGVDpiavADIQK-----IIRHLKERGIG-VLITdHNVRETLGICDRAYIISEGKVLAEGTPEEILNNP 227
ABCC_MRP_Like cd03228
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ...
 5-216 1.03e-46

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213195 [Multi-domain]  Cd Length: 171  Bit Score: 156.39  E-value: 1.03e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQNT--PVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsKNTNLPVRERRL 82
Cdd:cd03228     1 IEFKNVSFSYPGRpkPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDL--RDLDLESLRKNI 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  83 GYLVQEGVLFpHLTVYRNIayglgngkgrtaqerqrieamleltgiselagrypheLSGGQQQRVALARALAPDPELILL 162
Cdd:cd03228    79 AYVPQDPFLF-SGTIRENI-------------------------------------LSGGQRQRIAIARALLRDPPILIL 120

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1067578656 163 DEPFSALDEQLRRQIREDMIAALRanGKSAVFVSHdREEALQYADRIAVMKQGR 216
Cdd:cd03228   121 DEATSALDPETEALILEALRALAK--GKTVIVIAH-RLSTIRDADRIIVLDDGR 171
YbbA COG4181
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ...
 2-221 1.35e-46

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443338 [Multi-domain]  Cd Length: 233  Bit Score: 157.98  E-value: 1.35e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   2 TAALHIGHLSKSFQNT----PVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNTN--L 75
Cdd:COG4181     6 APIIELRGLTKTVGTGagelTILKGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTVRLAGQDLFALDEDarA 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  76 PVRERRLGYLVQEGVLFPHLTVYRNIAYGL---GNgkgrtAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARA 152
Cdd:COG4181    86 RLRARHVGFVFQSFQLLPTLTALENVMLPLelaGR-----RDARARARALLERVGLGHRLDHYPAQLSGGEQQRVALARA 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1067578656 153 LAPDPELILLDEPFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQyADRIAVMKQGRILQTA 221
Cdd:COG4181   161 FATEPAILFADEPTGNLDAATGEQIIDLLFELNRERGTTLVLVTHDPALAAR-CDRVLRLRAGRLVEDT 228
ABC_TM1139_LivF_branched cd03224
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...
 17-226 1.66e-46

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.


Pssm-ID: 213191 [Multi-domain]  Cd Length: 222  Bit Score: 157.60  E-value: 1.66e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  17 TPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRER-RLGY-LVQEG-VLFP 93
Cdd:cd03224    13 SQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDI----TGLPPHERaRAGIgYVPEGrRIFP 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  94 HLTVYRNIAYGLGNGKGRTAQErqRIEAMLEL-TGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDEQ 172
Cdd:cd03224    89 ELTVEENLLLGAYARRRAKRKA--RLERVYELfPRLKERRKQLAGTLSGGEQQMLAIARALMSRPKLLLLDEPSEGLAPK 166

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1067578656 173 LRRQIrEDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHEL 226
Cdd:cd03224   167 IVEEI-FEAIRELRDEGVTILLVEQNARFALEIADRAYVLERGRVVLEGTAAEL 219
PstB COG1117
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 1-232 2.84e-46

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440734 [Multi-domain]  Cd Length: 258  Bit Score: 157.89  E-value: 2.84e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   1 MTAALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCL-------AGFEQpdSGEISLSGKTIFSKNT 73
Cdd:COG1117     8 LEPKIEVRNLNVYYGDKQALKDINLDIPENKVTALIGPSGCGKSTLLRCLnrmndliPGARV--EGEILLDGEDIYDPDV 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  74 NLP-VReRRLGYLVQEGVLFPHlTVYRNIAYGLG-NGKGRTAQERQRIEAMLELTGI-SELAGR---YPHELSGGQQQRV 147
Cdd:COG1117    86 DVVeLR-RRVGMVFQKPNPFPK-SIYDNVAYGLRlHGIKSKSELDEIVEESLRKAALwDEVKDRlkkSALGLSGGQQQRL 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 148 ALARALAPDPELILLDEPFSALDEQLRRQIrEDMIAALRANgKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELY 227
Cdd:COG1117   164 CIARALAVEPEVLLMDEPTSALDPISTAKI-EELILELKKD-YTIVIVTHNMQQAARVSDYTAFFYLGELVEFGPTEQIF 241


                  ....*
gi 1067578656 228 RQPAD 232
Cdd:COG1117   242 TNPKD 246
CeuD COG4604
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ...
 7-226 3.34e-46

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443654 [Multi-domain]  Cd Length: 252  Bit Score: 157.55  E-value: 3.34e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   7 IGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsKNTNLPVRERRLGYLV 86
Cdd:COG4604     4 IKNVSKRYGGKVVLDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDGLDV--ATTPSRELAKRLAILR 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  87 QEGVLFPHLTVYRNIAYG-LGNGKGR-TAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDE 164
Cdd:COG4604    82 QENHINSRLTVRELVAFGrFPYSKGRlTAEDREIIDEAIAYLDLEDLADRYLDELSGGQRQRAFIAMVLAQDTDYVLLDE 161

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1067578656 165 PFSALDEQLRRQiredMIAALR--AN--GKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHEL 226
Cdd:COG4604   162 PLNNLDMKHSVQ----MMKLLRrlADelGKTVVIVLHDINFASCYADHIVAMKDGRVVAQGTPEEI 223
cbiO PRK13634
cobalt transporter ATP-binding subunit; Provisional
 16-235 3.40e-46

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237454 [Multi-domain]  Cd Length: 290  Bit Score: 159.03  E-value: 3.40e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  16 NTP----VLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFS--KNTNLPVRERRLGYLVQ-- 87
Cdd:PRK13634   15 KTPferrALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIGERVITAgkKNKKLKPLRKKVGIVFQfp 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  88 EGVLFPHlTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGISE-LAGRYPHELSGGQQQRVALARALAPDPELILLDEPF 166
Cdd:PRK13634   95 EHQLFEE-TVEKDICFGPMNFGVSEEDAKQKAREMIELVGLPEeLLARSPFELSGGQMRRVAIAGVLAMEPEVLVLDEPT 173

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 167 SALDEQLRRQIREdMIAAL-RANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPADLDA 235
Cdd:PRK13634  174 AGLDPKGRKEMME-MFYKLhKEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTPREIFADPDELEA 242
FtsE TIGR02673
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC ...
 9-216 3.47e-46

cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC transporter ATP-binding protein family. This protein, and its permease partner FtsX, localize to the division site. In a number of species, the ftsEX gene pair is located next to FtsY, the signal recognition particle-docking protein. [Cellular processes, Cell division]


Pssm-ID: 131721 [Multi-domain]  Cd Length: 214  Bit Score: 156.64  E-value: 3.47e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   9 HLSKSFQ-NTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFS-KNTNLPVRERRLGYLV 86
Cdd:TIGR02673   6 NVSKAYPgGVAALHDVSLHIRKGEFLFLTGPSGAGKTTLLKLLYGALTPSRGQVRIAGEDVNRlRGRQLPLLRRRIGVVF 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  87 QEGVLFPHLTVYRNIAYGLgNGKGRTAQE-RQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEP 165
Cdd:TIGR02673  86 QDFRLLPDRTVYENVALPL-EVRGKKEREiQRRVGAALRQVGLEHKADAFPEQLSGGEQQRVAIARAIVNSPPLLLADEP 164

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1067578656 166 FSALDEQLRRQIReDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGR 216
Cdd:TIGR02673 165 TGNLDPDLSERIL-DLLKRLNKRGTTVIVATHDLSLVDRVAHRVIILDDGR 214
ABC_ATP_DarD NF038007
darobactin export ABC transporter ATP-binding protein;
9-217 1.09e-45

darobactin export ABC transporter ATP-binding protein;


Pssm-ID: 411600 [Multi-domain]  Cd Length: 218  Bit Score: 155.26  E-value: 1.09e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   9 HLSKSFQnTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTI--FSKNTNLPVRERRLGYLV 86
Cdd:NF038007   11 YITKTIK-TKVLNHLNFSVEKGDFVSIMGPSGSGKSTLLNIIGMFDSLDSGSLTLAGKEVtnLSYSQKIILRRELIGYIF 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  87 QEGVLFPHLTVYRNIAYGLgngKGRTAQERQRIEAM---LELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLD 163
Cdd:NF038007   90 QSFNLIPHLSIFDNVALPL---KYRGVAKKERIERVnqvLNLFGIDNRRNHKPMQLSGGQQQRVAIARAMVSNPALLLAD 166

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1067578656 164 EPFSALDEQLRRQIREDMiAALRANGKSAVFVSHDrEEALQYADRIAVMKQGRI 217
Cdd:NF038007  167 EPTGNLDSKNARAVLQQL-KYINQKGTTIIMVTHS-DEASTYGNRIINMKDGKL 218
3a0107s01c2 TIGR00972
phosphate ABC transporter, ATP-binding protein; This model represents the ATP-binding protein ...
 4-232 2.64e-45

phosphate ABC transporter, ATP-binding protein; This model represents the ATP-binding protein of a family of ABC transporters for inorganic phosphate. In the model species Escherichia coli, a constitutive transporter for inorganic phosphate, with low affinity, is also present. The high affinity transporter that includes this polypeptide is induced when extracellular phosphate concentrations are low. The proteins most similar to the members of this family but not included appear to be amino acid transporters. [Transport and binding proteins, Anions]


Pssm-ID: 273372 [Multi-domain]  Cd Length: 247  Bit Score: 155.15  E-value: 2.64e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   4 ALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCL-----AGFEQPDSGEISLSGKTIFSKNTNLPVR 78
Cdd:TIGR00972   1 AIEIENLNLFYGEKEALKNINLDIPKNQVTALIGPSGCGKSTLLRSLnrmndLVPGVRIEGKVLFDGQDIYDKKIDVVEL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  79 ERRLGYLVQEGVLFPhLTVYRNIAYGL-GNGKGRTAQERQRIEAMLELTGI-SELAGR---YPHELSGGQQQRVALARAL 153
Cdd:TIGR00972  81 RRRVGMVFQKPNPFP-MSIYDNIAYGPrLHGIKDKKELDEIVEESLKKAALwDEVKDRlhdSALGLSGGQQQRLCIARAL 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1067578656 154 APDPELILLDEPFSALDEQLRRQIrEDMIAALRANgKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPAD 232
Cdd:TIGR00972 160 AVEPEVLLLDEPTSALDPIATGKI-EELIQELKKK-YTIVIVTHNMQQAARISDRTAFFYDGELVEYGPTEQIFTNPKE 236
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 20-230 4.54e-45

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 161.78  E-value: 4.54e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  20 LNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFeQPDSGEISLSGKTI--FSKNTNLPVReRRLGYLVQE--GVLFPHL 95
Cdd:COG4172   302 VDGVSLTLRRGETLGLVGESGSGKSTLGLALLRL-IPSEGEIRFDGQDLdgLSRRALRPLR-RRMQVVFQDpfGSLSPRM 379

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  96 TVYRNIAYGLG-NGKGRTAQER-QRIEAMLELTGIS-ELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDEQ 172
Cdd:COG4172   380 TVGQIIAEGLRvHGPGLSAAERrARVAEALEEVGLDpAARHRYPHEFSGGQRQRIAIARALILEPKLLVLDEPTSALDVS 459

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1067578656 173 LRRQIReDMIAAL-RANGKSAVFVSHDRE--EALqyADRIAVMKQGRILQTASPHELYRQP 230
Cdd:COG4172   460 VQAQIL-DLLRDLqREHGLAYLFISHDLAvvRAL--AHRVMVMKDGKVVEQGPTEQVFDAP 517
ArtP COG4161
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
4-230 5.07e-45

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443326 [Multi-domain]  Cd Length: 242  Bit Score: 154.40  E-value: 5.07e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   4 ALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTI-FSKNTNLP-VRE-- 79
Cdd:COG4161     2 SIQLKNINCFYGSHQALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAGHQFdFSQKPSEKaIRLlr 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  80 RRLGYLVQEGVLFPHLTVYRNIAYG----LGNGKgrtAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAP 155
Cdd:COG4161    82 QKVGMVFQQYNLWPHLTVMENLIEApckvLGLSK---EQAREKAMKLLARLRLTDKADRFPLHLSGGQQQRVAIARALMM 158

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1067578656 156 DPELILLDEPFSALDEQLRRQIREdMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASpHELYRQP 230
Cdd:COG4161   159 EPQVLLFDEPTAALDPEITAQVVE-IIRELSQTGITQVIVTHEVEFARKVASQVVYMEKGRIIEQGD-ASHFTQP 231
metN PRK11153
DL-methionine transporter ATP-binding subunit; Provisional
 9-277 1.43e-44

DL-methionine transporter ATP-binding subunit; Provisional


Pssm-ID: 236863 [Multi-domain]  Cd Length: 343  Bit Score: 156.11  E-value: 1.43e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   9 HLSKSFQ----NTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRE----R 80
Cdd:PRK11153    6 NISKVFPqggrTIHALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQDL----TALSEKElrkaR 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  81 RlgylvQEGVLFPHL------TVYRNIAYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALA 154
Cdd:PRK11153   82 R-----QIGMIFQHFnllssrTVFDNVALPLELAGTPKAEIKARVTELLELVGLSDKADRYPAQLSGGQKQRVAIARALA 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 155 PDPELILLDEPFSALDEQLRRQIReDMIAAL-RANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPADL 233
Cdd:PRK11153  157 SNPKVLLCDEATSALDPATTRSIL-ELLKDInRELGLTIVLITHEMDVVKRICDRVAVIDAGRLVEQGTVSEVFSHPKHP 235

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 1067578656 234 DAALFIGEGIvfpaalnADGTADCRLGRLPVQsgaPAGTRGTLL 277
Cdd:PRK11153  236 LTREFIQSTL-------HLDLPEDYLARLQAE---PTTGSGPLL 269
CydD COG4988
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ...
 15-229 1.65e-44

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444012 [Multi-domain]  Cd Length: 563  Bit Score: 160.69  E-value: 1.65e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  15 QNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsKNTNLPVRERRLGYLVQEGVLFpH 94
Cdd:COG4988   348 GGRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVDL--SDLDPASWRRQIAWVPQNPYLF-A 424

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  95 LTVYRNIAyglgngKGRTAQERQRIEAMLELTGISELAGRYPHE-----------LSGGQQQRVALARALAPDPELILLD 163
Cdd:COG4988   425 GTIRENLR------LGRPDASDEELEAALEAAGLDEFVAALPDGldtplgeggrgLSGGQAQRLALARALLRDAPLLLLD 498

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1067578656 164 EPFSALDEQLRRQIredmIAALR--ANGKSAVFVSHdREEALQYADRIAVMKQGRILQTASPHELYRQ 229
Cdd:COG4988   499 EPTAHLDAETEAEI----LQALRrlAKGRTVILITH-RLALLAQADRILVLDDGRIVEQGTHEELLAK 561
LivF COG0410
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ...
 18-237 2.16e-44

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];


Pssm-ID: 440179 [Multi-domain]  Cd Length: 236  Bit Score: 152.44  E-value: 2.16e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  18 PVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRER-RLGY-LVQEG-VLFPH 94
Cdd:COG0410    17 HVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDGEDI----TGLPPHRIaRLGIgYVPEGrRIFPS 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  95 LTVYRNIAYGLGNGKGRtAQERQRIEAMLEL-----TGISELAGRypheLSGGQQQRVALARALAPDPELILLDEPFSAL 169
Cdd:COG0410    93 LTVEENLLLGAYARRDR-AEVRADLERVYELfprlkERRRQRAGT----LSGGEQQMLAIGRALMSRPKLLLLDEPSLGL 167

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1067578656 170 DEQLRRQIrEDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPADLDAAL 237
Cdd:COG0410   168 APLIVEEI-FEIIRRLNREGVTILLVEQNARFALEIADRAYVLERGRIVLEGTAAELLADPEVREAYL 234
ECF_ATPase_1 TIGR04520
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
 9-233 2.89e-44

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275313 [Multi-domain]  Cd Length: 268  Bit Score: 152.97  E-value: 2.89e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   9 HLSKSFQNT--PVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNTNLPVReRRLGYLV 86
Cdd:TIGR04520   5 NVSFSYPESekPALKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLLPTSGKVTVDGLDTLDEENLWEIR-KKVGMVF 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  87 QEgvlfPH-----LTVYRNIAYGLGNgKGRTAQE-RQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELI 160
Cdd:TIGR04520  84 QN----PDnqfvgATVEDDVAFGLEN-LGVPREEmRKRVDEALKLVGMEDFRDREPHLLSGGQKQRVAIAGVLAMRPDII 158

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1067578656 161 LLDEPFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQyADRIAVMKQGRILQTASPHELYRQPADL 233
Cdd:TIGR04520 159 ILDEATSMLDPKGRKEVLETIRKLNKEEGITVISITHDMEEAVL-ADRVIVMNKGKIVAEGTPREIFSQVELL 230
modC PRK11144
molybdenum ABC transporter ATP-binding protein ModC;
22-217 3.29e-44

molybdenum ABC transporter ATP-binding protein ModC;


Pssm-ID: 182993 [Multi-domain]  Cd Length: 352  Bit Score: 155.42  E-value: 3.29e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  22 DISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIF--SKNTNLPVRERRLGYLVQEGVLFPHLTVYR 99
Cdd:PRK11144   16 TVNLTLPAQGITAIFGRSGAGKTSLINAISGLTRPQKGRIVLNGRVLFdaEKGICLPPEKRRIGYVFQDARLFPHYKVRG 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 100 NIAYGLgngkgrTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALD--------- 170
Cdd:PRK11144   96 NLRYGM------AKSMVAQFDKIVALLGIEPLLDRYPGSLSGGEKQRVAIGRALLTAPELLLMDEPLASLDlprkrellp 169

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1067578656 171 --EQLRRQIREDMIaalrangksavFVSHDREEALQYADRIAVMKQGRI 217
Cdd:PRK11144  170 ylERLAREINIPIL-----------YVSHSLDEILRLADRVVVLEQGKV 207
artP PRK11124
arginine transporter ATP-binding subunit; Provisional
 4-220 8.49e-44

arginine transporter ATP-binding subunit; Provisional


Pssm-ID: 182980 [Multi-domain]  Cd Length: 242  Bit Score: 151.32  E-value: 8.49e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   4 ALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTI-FSKNTNLP-VRE-- 79
Cdd:PRK11124    2 SIQLNGINCFYGAHQALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGNHFdFSKTPSDKaIRElr 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  80 RRLGYLVQEGVLFPHLTVYRNIAYG----LGNGKgrtAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAP 155
Cdd:PRK11124   82 RNVGMVFQQYNLWPHLTVQQNLIEApcrvLGLSK---DQALARAEKLLERLRLKPYADRFPLHLSGGQQQRVAIARALMM 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1067578656 156 DPELILLDEPFSALDEQLRRQIrEDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQT 220
Cdd:PRK11124  159 EPQVLLFDEPTAALDPEITAQI-VSIIRELAETGITQVIVTHEVEVARKTASRVVYMENGHIVEQ 222
MdlB COG1132
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
16-229 1.55e-43

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];


Pssm-ID: 440747 [Multi-domain]  Cd Length: 579  Bit Score: 158.02  E-value: 1.55e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  16 NTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRE--RRLGYLVQEGVLFp 93
Cdd:COG1132   352 DRPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDGVDI----RDLTLESlrRQIGVVPQDTFLF- 426

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  94 HLTVYRNIAYglgngkGRTAQERQRIEAMLELTGISELAGRYPH-----------ELSGGQQQRVALARALAPDPELILL 162
Cdd:COG1132   427 SGTIRENIRY------GRPDATDEEVEEAAKAAQAHEFIEALPDgydtvvgergvNLSGGQRQRIAIARALLKDPPILIL 500

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1067578656 163 DEPFSALDEQLRRQIREdMIAALRAnGKSAVFVSHdREEALQYADRIAVMKQGRILQTASPHELYRQ 229
Cdd:COG1132   501 DEATSALDTETEALIQE-ALERLMK-GRTTIVIAH-RLSTIRNADRILVLDDGRIVEQGTHEELLAR 564
ABC_cobalt_CbiO_domain2 cd03226
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ...
 6-217 1.67e-43

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213193 [Multi-domain]  Cd Length: 205  Bit Score: 149.33  E-value: 1.67e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   6 HIGHLSKSF-QNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKntnlpVRERRLGY 84
Cdd:cd03226     1 RIENISFSYkKGTEILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGKPIKAK-----ERRKSIGY 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  85 LVQE--GVLFPHlTVYRNIAYGLGNgkgrTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILL 162
Cdd:cd03226    76 VMQDvdYQLFTD-SVREELLLGLKE----LDAGNEQAETVLKDLDLYALKERHPLSLSGGQKQRLAIAAALLSGKDLLIF 150

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1067578656 163 DEPFSALD----EQLRRQIREdmiaaLRANGKSAVFVSHDREEALQYADRIAVMKQGRI 217
Cdd:cd03226   151 DEPTSGLDyknmERVGELIRE-----LAAQGKAVIVITHDYEFLAKVCDRVLLLANGAI 204
ABC_Carb_Monos_I cd03216
First domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 9-217 3.78e-43

First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213183 [Multi-domain]  Cd Length: 163  Bit Score: 146.80  E-value: 3.78e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   9 HLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNtnlPVRERRLG-YLVq 87
Cdd:cd03216     5 GITKRFGGVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKEVSFAS---PRDARRAGiAMV- 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  88 egvlfphltvyrniayglgngkgrtaqerqrieamleltgiselagrypHELSGGQQQRVALARALAPDPELILLDEPFS 167
Cdd:cd03216    81 -------------------------------------------------YQLSVGERQMVEIARALARNARLLILDEPTA 111

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1067578656 168 ALDEQLRRQIREdMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRI 217
Cdd:cd03216   112 ALTPAEVERLFK-VIRRLRAQGVAVIFISHRLDEVFEIADRVTVLRDGRV 160
PRK10070 PRK10070
proline/glycine betaine ABC transporter ATP-binding protein ProV;
20-232 4.55e-43

proline/glycine betaine ABC transporter ATP-binding protein ProV;


Pssm-ID: 182221 [Multi-domain]  Cd Length: 400  Bit Score: 153.65  E-value: 4.55e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  20 LNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTI--FSKNTNLPVRERRLGYLVQEGVLFPHLTV 97
Cdd:PRK10070   44 VKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIakISDAELREVRRKKIAMVFQSFALMPHMTV 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  98 YRNIAYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDEQLRRQI 177
Cdd:PRK10070  124 LDNTAFGMELAGINAEERREKALDALRQVGLENYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPLIRTEM 203

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1067578656 178 REDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPAD 232
Cdd:PRK10070  204 QDELVKLQAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEILNNPAN 258
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 1-248 7.37e-43

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 155.18  E-value: 7.37e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   1 MTAALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNtnlPVRER 80
Cdd:COG3845     2 MPPALELRGITKRFGGVVANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDGKPVRIRS---PRDAI 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  81 RLG-YLV-QEGVLFPHLTVYRNIAYGLGNGKG---RTAQERQRIEamleltgisELAGRYP---------HELSGGQQQR 146
Cdd:COG3845    79 ALGiGMVhQHFMLVPNLTVAENIVLGLEPTKGgrlDRKAARARIR---------ELSERYGldvdpdakvEDLSVGEQQR 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 147 VALARALAPDPELILLDEPFSALDEQlrrQIRE--DMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPH 224
Cdd:COG3845   150 VEILKALYRGARILILDEPTAVLTPQ---EADElfEILRRLAAEGKSIIFITHKLREVMAIADRVTVLRRGKVVGTVDTA 226

                         250       260
                  ....*....|....*....|....
gi 1067578656 225 ELyrQPADLdAALFIGEGIVFPAA 248
Cdd:COG3845   227 ET--SEEEL-AELMVGREVLLRVE 247
ABC_BcrA_bacitracin_resist cd03268
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ...
 5-218 7.39e-43

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.


Pssm-ID: 213235 [Multi-domain]  Cd Length: 208  Bit Score: 147.75  E-value: 7.39e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKtIFSKNTNLPvreRRLGY 84
Cdd:cd03268     1 LKTNDLTKTYGKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGK-SYQKNIEAL---RRIGA 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  85 LVQEGVLFPHLTVYRNIAYgLGNGKGRtaqERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDE 164
Cdd:cd03268    77 LIEAPGFYPNLTARENLRL-LARLLGI---RKKRIDEVLDVVGLKDSAKKKVKGFSLGMKQRLGIALALLGNPDLLILDE 152

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1067578656 165 PFSALDEQLRRQIREdMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRIL 218
Cdd:cd03268   153 PTNGLDPDGIKELRE-LILSLRDQGITVLISSHLLSEIQKVADRIGIINKGKLI 205
ABCC_bacteriocin_exporters cd03245
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...
 15-217 1.02e-42

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.


Pssm-ID: 213212 [Multi-domain]  Cd Length: 220  Bit Score: 147.74  E-value: 1.02e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  15 QNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsKNTNLPVRERRLGYLVQEGVLFpH 94
Cdd:cd03245    15 QEIPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDI--RQLDPADLRRNIGYVPQDVTLF-Y 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  95 LTVYRNIAYGLGNGkgrtaqERQRIEAMLELTGISELAGRYPH-----------ELSGGQQQRVALARALAPDPELILLD 163
Cdd:cd03245    92 GTLRDNITLGAPLA------DDERILRAAELAGVTDFVNKHPNgldlqigergrGLSGGQRQAVALARALLNDPPILLLD 165

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1067578656 164 EPFSALDEQLRRQIREDMIAALRanGKSAVFVSHdREEALQYADRIAVMKQGRI 217
Cdd:cd03245   166 EPTSAMDMNSEERLKERLRQLLG--DKTLIIITH-RPSLLDLVDRIIVMDSGRI 216
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 1-231 3.78e-42

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 153.69  E-value: 3.78e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   1 MTAALHIGHLSKSFQN----TPVLNDISLSLDPGEILFIIGASGCGKT----TLLRCLAGFEQPDSGEISLSGKTIFSkn 72
Cdd:COG4172     3 SMPLLSVEDLSVAFGQgggtVEAVKGVSFDIAAGETLALVGESGSGKSvtalSILRLLPDPAAHPSGSILFDGQDLLG-- 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  73 tnLP------VRERRLGYLVQEGV--LFPHLTVYRNIAYGLGNGKGRTAQE-RQRIEAMLELTGISELAGR---YPHELS 140
Cdd:COG4172    81 --LSerelrrIRGNRIAMIFQEPMtsLNPLHTIGKQIAEVLRLHRGLSGAAaRARALELLERVGIPDPERRldaYPHQLS 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 141 GGQQQRVALARALAPDPELILLDEPFSALDEQLRRQIReDMIAALRA-NGKSAVFVSHD----ReealQYADRIAVMKQG 215
Cdd:COG4172   159 GGQRQRVMIAMALANEPDLLIADEPTTALDVTVQAQIL-DLLKDLQReLGMALLLITHDlgvvR----RFADRVAVMRQG 233

                         250
                  ....*....|....*.
gi 1067578656 216 RILQTASPHELYRQPA 231
Cdd:COG4172   234 EIVEQGPTAELFAAPQ 249
CydC COG4987
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ...
 15-231 6.62e-42

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444011 [Multi-domain]  Cd Length: 569  Bit Score: 153.38  E-value: 6.62e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  15 QNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsKNTNLPVRERRLGYLVQEGVLFpH 94
Cdd:COG4987   346 AGRPVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGGVDL--RDLDEDDLRRRIAVVPQRPHLF-D 422

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  95 LTVYRNIAygLGNGkgrTAQERQrIEAMLELTGISELAGRYPH-----------ELSGGQQQRVALARALAPDPELILLD 163
Cdd:COG4987   423 TTLRENLR--LARP---DATDEE-LWAALERVGLGDWLAALPDgldtwlgeggrRLSGGERRRLALARALLRDAPILLLD 496

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1067578656 164 EPFSALDEQLRRQIREDMIAALRanGKSAVFVSHdREEALQYADRIAVMKQGRILQTASPHELYRQPA 231
Cdd:COG4987   497 EPTEGLDAATEQALLADLLEALA--GRTVLLITH-RLAGLERMDRILVLEDGRIVEQGTHEELLAQNG 561
ssuB PRK11247
aliphatic sulfonates transport ATP-binding subunit; Provisional
 5-217 1.02e-41

aliphatic sulfonates transport ATP-binding subunit; Provisional


Pssm-ID: 183055 [Multi-domain]  Cd Length: 257  Bit Score: 146.36  E-value: 1.02e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEIsLSGKTIFSKntnlpVRER-RLg 83
Cdd:PRK11247   13 LLLNAVSKRYGERTVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGEL-LAGTAPLAE-----AREDtRL- 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  84 yLVQEGVLFPHLTVYRNIAYGLGnGKGRTAQERQrieamLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLD 163
Cdd:PRK11247   86 -MFQDARLLPWKKVIDNVGLGLK-GQWRDAALQA-----LAAVGLADRANEWPAALSGGQKQRVALARALIHRPGLLLLD 158

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1067578656 164 EPFSALDeQLRRQIREDMIAAL-RANGKSAVFVSHDREEALQYADRIAVMKQGRI 217
Cdd:PRK11247  159 EPLGALD-ALTRIEMQDLIESLwQQHGFTVLLVTHDVSEAVAMADRVLLIEEGKI 212
PRK10619 PRK10619
histidine ABC transporter ATP-binding protein HisP;
5-230 1.41e-41

histidine ABC transporter ATP-binding protein HisP;


Pssm-ID: 182592 [Multi-domain]  Cd Length: 257  Bit Score: 145.88  E-value: 1.41e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTI------------FSKN 72
Cdd:PRK10619    6 LNVIDLHKRYGEHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTInlvrdkdgqlkvADKN 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  73 tNLPVRERRLGYLVQEGVLFPHLTVYRNIAYGLGNGKGRTAQE-RQRIEAMLELTGISELA-GRYPHELSGGQQQRVALA 150
Cdd:PRK10619   86 -QLRLLRTRLTMVFQHFNLWSHMTVLENVMEAPIQVLGLSKQEaRERAVKYLAKVGIDERAqGKYPVHLSGGQQQRVSIA 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 151 RALAPDPELILLDEPFSALDEQLRRQIREDMiAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQP 230
Cdd:PRK10619  165 RALAMEPEVLLFDEPTSALDPELVGEVLRIM-QQLAEEGKTMVVVTHEMGFARHVSSHVIFLHQGKIEEEGAPEQLFGNP 243
ABC_drug_resistance_like cd03264
ABC-type multidrug transport system, ATPase component; The biological function of this family ...
 5-219 1.54e-41

ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213231 [Multi-domain]  Cd Length: 211  Bit Score: 144.26  E-value: 1.54e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQNTPVLNDISLSLDPGeILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNTNLpvrERRLGY 84
Cdd:cd03264     1 LQLENLTKRYGKKRALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTIRIDGQDVLKQPQKL---RRRIGY 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  85 LVQEGVLFPHLTVYRNIAYgLGNGKG-RTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLD 163
Cdd:cd03264    77 LPQEFGVYPNFTVREFLDY-IAWLKGiPSKEVKARVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPSILIVD 155

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1067578656 164 EPFSALDEQLRRQIREdMIAALRANgKSAVFVSHDREEALQYADRIAVMKQGRILQ 219
Cdd:cd03264   156 EPTAGLDPEERIRFRN-LLSELGED-RIVILSTHIVEDVESLCNQVAVLNKGKLVF 209
ArpD COG4618
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ...
 15-217 2.84e-41

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443660 [Multi-domain]  Cd Length: 563  Bit Score: 151.82  E-value: 2.84e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  15 QNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNtnlpvRE---RRLGYLVQEGVL 91
Cdd:COG4618   343 SKRPILRGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSVRLDGADLSQWD-----REelgRHIGYLPQDVEL 417

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  92 FPHlTVYRNIAyglgngkgRTAQ-ERQRIEAMLELTGISELAGRYP-----------HELSGGQQQRVALARALAPDPEL 159
Cdd:COG4618   418 FDG-TIAENIA--------RFGDaDPEKVVAAAKLAGVHEMILRLPdgydtrigeggARLSGGQRQRIGLARALYGDPRL 488

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1067578656 160 ILLDEPFSALDEQLRRQIREdMIAALRANGKSAVFVSHdREEALQYADRIAVMKQGRI 217
Cdd:COG4618   489 VVLDEPNSNLDDEGEAALAA-AIRALKARGATVVVITH-RPSLLAAVDKLLVLRDGRV 544
ABC_DrrA cd03265
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...
 9-226 2.87e-41

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213232 [Multi-domain]  Cd Length: 220  Bit Score: 144.05  E-value: 2.87e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   9 HLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNTNlpVReRRLGYLVQE 88
Cdd:cd03265     5 NLVKKYGDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHDVVREPRE--VR-RRIGIVFQD 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  89 GVLFPHLTVYRNIA-----YGLGNgkgrtAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLD 163
Cdd:cd03265    82 LSVDDELTGWENLYiharlYGVPG-----AERRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPEVLFLD 156

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1067578656 164 EPFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHEL 226
Cdd:cd03265   157 EPTIGLDPQTRAHVWEYIEKLKEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGTPEEL 219
nickel_nikE TIGR02769
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ...
 5-231 3.80e-41

nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131816 [Multi-domain]  Cd Length: 265  Bit Score: 144.95  E-value: 3.80e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSF---------QNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNTNL 75
Cdd:TIGR02769   3 LEVRDVTHTYrtgglfgakQRAPVLTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKPAQGTVSFRGQDLYQLDRKQ 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  76 PVRERRLGYLVQE---GVLFPHLTVYRNIAYGLGNGKGRTAQERQ-RIEAMLELTGI-SELAGRYPHELSGGQQQRVALA 150
Cdd:TIGR02769  83 RRAFRRDVQLVFQdspSAVNPRMTVRQIIGEPLRHLTSLDESEQKaRIAELLDMVGLrSEDADKLPRQLSGGQLQRINIA 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 151 RALAPDPELILLDEPFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHEL--YR 228
Cdd:TIGR02769 163 RALAVKPKLIVLDEAVSNLDMVLQAVILELLRKLQQAFGTAYLFITHDLRLVQSFCQRVAVMDKGQIVEECDVAQLlsFK 242


                  ...
gi 1067578656 229 QPA 231
Cdd:TIGR02769 243 HPA 245
ABCC_Protease_Secretion cd03246
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...
 16-217 6.19e-41

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.


Pssm-ID: 213213 [Multi-domain]  Cd Length: 173  Bit Score: 141.58  E-value: 6.19e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  16 NTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNTNLpvRERRLGYLVQEGVLFPHl 95
Cdd:cd03246    14 EPPVLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQWDPNE--LGDHVGYLPQDDELFSG- 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  96 TVYRNIayglgngkgrtaqerqrieamleltgiselagrypheLSGGQQQRVALARALAPDPELILLDEPFSALDEQLRR 175
Cdd:cd03246    91 SIAENI-------------------------------------LSGGQRQRLGLARALYGNPRILVLDEPNSHLDVEGER 133

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 1067578656 176 QIrEDMIAALRANGKSAVFVSHdREEALQYADRIAVMKQGRI 217
Cdd:cd03246   134 AL-NQAIAALKAAGATRIVIAH-RPETLASADRILVLEDGRV 173
ABC_FtsE cd03292
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...
 16-217 7.51e-41

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages


Pssm-ID: 213259 [Multi-domain]  Cd Length: 214  Bit Score: 142.55  E-value: 7.51e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  16 NTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFS-KNTNLPVRERRLGYLVQEGVLFPH 94
Cdd:cd03292    13 GTAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDVSDlRGRAIPYLRRKIGVVFQDFRLLPD 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  95 LTVYRNIAYGL--GNGKGRTAQERqrIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDEQ 172
Cdd:cd03292    93 RNVYENVAFALevTGVPPREIRKR--VPAALELVGLSHKHRALPAELSGGEQQRVAIARAIVNSPTILIADEPTGNLDPD 170

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1067578656 173 LRRQIReDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRI 217
Cdd:cd03292   171 TTWEIM-NLLKKINKAGTTVVVATHAKELVDTTRHRVIALERGKL 214
cbiO PRK13635
energy-coupling factor ABC transporter ATP-binding protein;
5-251 7.75e-41

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184195 [Multi-domain]  Cd Length: 279  Bit Score: 144.39  E-value: 7.75e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQNT--PVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfSKNTNLPVReRRL 82
Cdd:PRK13635    6 IRVEHISFRYPDAatYALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGMVL-SEETVWDVR-RQV 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  83 GYLVQE-GVLFPHLTVYRNIAYGLGN-GKGRTaQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELI 160
Cdd:PRK13635   84 GMVFQNpDNQFVGATVQDDVAFGLENiGVPRE-EMVERVDQALRQVGMEDFLNREPHRLSGGQKQRVAIAGVLALQPDII 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 161 LLDEPFSALDEQLRRQIREdMIAALRANGKSAVF-VSHDREEALQyADRIAVMKQGRILQTASPHELYRQPADLDAalfI 239
Cdd:PRK13635  163 ILDEATSMLDPRGRREVLE-TVRQLKEQKGITVLsITHDLDEAAQ-ADRVIVMNKGEILEEGTPEEIFKSGHMLQE---I 237

                         250
                  ....*....|..
gi 1067578656 240 GEGIVFPAALNA 251
Cdd:PRK13635  238 GLDVPFSVKLKE 249
SapF COG4167
ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];
1-230 2.04e-40

ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];


Pssm-ID: 443328 [Multi-domain]  Cd Length: 265  Bit Score: 143.05  E-value: 2.04e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   1 MTAALHIGHLSKSF---------QNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSK 71
Cdd:COG4167     1 MSALLEVRNLSKTFkyrtglfrrQQFEAVKPVSFTLEAGQTLAIIGENGSGKSTLAKMLAGIIEPTSGEILINGHKLEYG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  72 NTnlPVRERRLGYLVQ--EGVLFPHLTVYRNIAYGLGNGKGRTAQER-QRIEAMLELTGIS-ELAGRYPHELSGGQQQRV 147
Cdd:COG4167    81 DY--KYRCKHIRMIFQdpNTSLNPRLNIGQILEEPLRLNTDLTAEEReERIFATLRLVGLLpEHANFYPHMLSSGQKQRV 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 148 ALARALAPDPELILLDEPFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELY 227
Cdd:COG4167   159 ALARALILQPKIIIADEALAALDMSVRSQIINLMLELQEKLGISYIYVSQHLGIVKHISDKVLVMHQGEVVEYGKTAEVF 238


                  ...
gi 1067578656 228 RQP 230
Cdd:COG4167   239 ANP 241
ABC_NatA_sodium_exporter cd03266
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...
 5-218 3.74e-40

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.


Pssm-ID: 213233 [Multi-domain]  Cd Length: 218  Bit Score: 140.97  E-value: 3.74e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQNTP----VLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGktiFSKNTNLPVRER 80
Cdd:cd03266     2 ITADALTKRFRDVKktvqAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDG---FDVVKEPAEARR 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  81 RLGYLVQEGVLFPHLTVYRNIAY--GLGNGKGRTAQerQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPE 158
Cdd:cd03266    79 RLGFVSDSTGLYDRLTARENLEYfaGLYGLKGDELT--ARLEELADRLGMEELLDRRVGGFSTGMRQKVAIARALVHDPP 156

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 159 LILLDEPFSALDEQLRRQIREdMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRIL 218
Cdd:cd03266   157 VLLLDEPTTGLDVMATRALRE-FIRQLRALGKCILFSTHIMQEVERLCDRVVVLHRGRVV 215
ABCC_ATM1_transporter cd03253
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ...
 18-226 5.81e-40

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213220 [Multi-domain]  Cd Length: 236  Bit Score: 140.83  E-value: 5.81e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  18 PVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsKNTNLPVRERRLGYLVQEGVLFpHLTV 97
Cdd:cd03253    15 PVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDI--REVTLDSLRRAIGVVPQDTVLF-NDTI 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  98 YRNIAYGLGNgkgrtAQERQRIEAMlELTGISELAGRYPH-----------ELSGGQQQRVALARALAPDPELILLDEPF 166
Cdd:cd03253    92 GYNIRYGRPD-----ATDEEVIEAA-KAAQIHDKIMRFPDgydtivgerglKLSGGEKQRVAIARAILKNPPILLLDEAT 165

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 167 SALDEQLRRQIREDMIAAlrANGKSAVFVSHdREEALQYADRIAVMKQGRILQTASPHEL 226
Cdd:cd03253   166 SALDTHTEREIQAALRDV--SKGRTTIVIAH-RLSTIVNADKIIVLKDGRIVERGTHEEL 222
ABC_MTABC3_MDL1_MDL2 cd03249
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ...
 16-229 8.97e-40

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.


Pssm-ID: 213216 [Multi-domain]  Cd Length: 238  Bit Score: 140.37  E-value: 8.97e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  16 NTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsKNTNLPVRERRLGYLVQEGVLFPhL 95
Cdd:cd03249    15 DVPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGVDI--RDLNLRWLRSQIGLVSQEPVLFD-G 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  96 TVYRNIAYGLGNgkgRTAQERQRIEAMLELT--------GISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFS 167
Cdd:cd03249    92 TIAENIRYGKPD---ATDEEVEEAAKKANIHdfimslpdGYDTLVGERGSQLSGGQKQRIAIARALLRNPKILLLDEATS 168

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1067578656 168 ALDEQLRRQIREDMIAALRanGKSAVFVSHdREEALQYADRIAVMKQGRILQTASPHELYRQ 229
Cdd:cd03249   169 ALDAESEKLVQEALDRAMK--GRTTIVIAH-RLSTIRNADLIAVLQNGQVVEQGTHDELMAQ 227
type_I_sec_LssB TIGR03375
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some ...
 15-218 1.47e-39

type I secretion system ATPase, LssB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. This model is related to models TIGR01842 and TIGR01846, and to bacteriocin ABC transporters that cleave their substrates during export. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]


Pssm-ID: 274550 [Multi-domain]  Cd Length: 694  Bit Score: 148.48  E-value: 1.47e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  15 QNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRERR--LGYLVQEGVLF 92
Cdd:TIGR03375 476 QETPALDNVSLTIRPGEKVAIIGRIGSGKSTLLKLLLGLYQPTEGSVLLDGVDI----RQIDPADLRrnIGYVPQDPRLF 551

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  93 pHLTVYRNIAYGlgngkgRTAQERQRIEAMLELTGISELAGRYPH-----------ELSGGQQQRVALARALAPDPELIL 161
Cdd:TIGR03375 552 -YGTLRDNIALG------APYADDEEILRAAELAGVTEFVRRHPDgldmqigergrSLSGGQRQAVALARALLRDPPILL 624

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1067578656 162 LDEPFSALDEQLRRQIREDMIAALRanGKSAVFVSHdREEALQYADRIAVMKQGRIL 218
Cdd:TIGR03375 625 LDEPTSAMDNRSEERFKDRLKRWLA--GKTLVLVTH-RTSLLDLVDRIIVMDNGRIV 678
ModF COG1119
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ...
 2-218 3.39e-39

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];


Pssm-ID: 440736 [Multi-domain]  Cd Length: 250  Bit Score: 139.45  E-value: 3.39e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   2 TAALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSG-EISLSGKTIFSKNtnlpVRE- 79
Cdd:COG1119     1 DPLLELRNVTVRRGGKTILDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYGnDVRLFGERRGGED----VWEl 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  80 -RRLGYLVQEGVLF--PHLTVYRNIAYGLGNGKGR----TAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARA 152
Cdd:COG1119    77 rKRIGLVSPALQLRfpRDETVLDVVLSGFFDSIGLyrepTDEQRERARELLELLGLAHLADRPFGTLSQGEQRRVLIARA 156

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1067578656 153 LAPDPELILLDEPFSALDEQLRRQIREdMIAALRANGKSA-VFVSHDREEALQYADRIAVMKQGRIL 218
Cdd:COG1119   157 LVKDPELLILDEPTAGLDLGARELLLA-LLDKLAAEGAPTlVLVTHHVEEIPPGITHVLLLKDGRVV 222
ABC_Carb_Monos_II cd03215
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 19-217 7.24e-39

Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213182 [Multi-domain]  Cd Length: 182  Bit Score: 136.41  E-value: 7.24e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  19 VLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRERR---LGYL----VQEGvL 91
Cdd:cd03215    15 AVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPV----TRRSPRDAIragIAYVpedrKREG-L 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  92 FPHLTVYRNIAyglgngkgrtaqerqrieamleltgISELagrypheLSGGQQQRVALARALAPDPELILLDEPFSALDE 171
Cdd:cd03215    90 VLDLSVAENIA-------------------------LSSL-------LSGGNQQKVVLARWLARDPRVLILDEPTRGVDV 137

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1067578656 172 QLRRQIREdMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRI 217
Cdd:cd03215   138 GAKAEIYR-LIRELADAGKAVLLISSELDELLGLCDRILVMYEGRI 182
cbiO PRK13632
cobalt transporter ATP-binding subunit; Provisional
 2-226 1.93e-38

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237452 [Multi-domain]  Cd Length: 271  Bit Score: 137.81  E-value: 1.93e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   2 TAALHIGHLSKSFQN--TPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNtnlpVRE 79
Cdd:PRK13632    5 SVMIKVENVSFSYPNseNNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITISKEN----LKE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  80 RR--LGYLVQE-GVLFPHLTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPD 156
Cdd:PRK13632   81 IRkkIGIIFQNpDNQFIGATVEDDIAFGLENKKVPPKKMKDIIDDLAKKVGMEDYLDKEPQNLSGGQKQRVAIASVLALN 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1067578656 157 PELILLDEPFSALDEQLRRQIREdMIAALRANGKSAVF-VSHDREEALQyADRIAVMKQGRILQTASPHEL 226
Cdd:PRK13632  161 PEIIIFDESTSMLDPKGKREIKK-IMVDLRKTRKKTLIsITHDMDEAIL-ADKVIVFSEGKLIAQGKPKEI 229
cbiO PRK13637
energy-coupling factor transporter ATPase;
20-229 2.39e-38

energy-coupling factor transporter ATPase;


Pssm-ID: 237455 [Multi-domain]  Cd Length: 287  Bit Score: 138.26  E-value: 2.39e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  20 LNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNTNLPVRERRLGYLVQ--EGVLFPHlTV 97
Cdd:PRK13637   23 LDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVDITDKKVKLSDIRKKVGLVFQypEYQLFEE-TI 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  98 YRNIAYGLGNgKGRTAQE-RQRIEAMLELTGIS--ELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDEQLR 174
Cdd:PRK13637  102 EKDIAFGPIN-LGLSEEEiENRVKRAMNIVGLDyeDYKDKSPFELSGGQKRRVAIAGVVAMEPKILILDEPTAGLDPKGR 180

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1067578656 175 RQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQ 229
Cdd:PRK13637  181 DEILNKIKELHKEYNMTIILVSHSMEDVAKLADRIIVMNKGKCELQGTPREVFKE 235
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
18-212 2.54e-38

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 135.05  E-value: 2.54e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  18 PVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKtifskntnlpvreRRLGYLVQEGVL---FPh 94
Cdd:NF040873    6 PVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRAGG-------------ARVAYVPQRSEVpdsLP- 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  95 LTVYRNIAYGLGNGKGR----TAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALD 170
Cdd:NF040873   72 LTVRDLVAMGRWARRGLwrrlTRDDRAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTGLD 151

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 1067578656 171 EQLRRQIReDMIAALRANGKSAVFVSHDREEALQyADRIAVM 212
Cdd:NF040873  152 AESRERII-ALLAEEHARGATVVVVTHDLELVRR-ADPCVLL 191
cbiO PRK13650
energy-coupling factor transporter ATPase;
1-234 5.26e-38

energy-coupling factor transporter ATPase;


Pssm-ID: 184209 [Multi-domain]  Cd Length: 279  Bit Score: 137.17  E-value: 5.26e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   1 MTAALHIGHLS---KSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNtnlpV 77
Cdd:PRK13650    1 MSNIIEVKNLTfkyKEDQEKYTLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDLLTEEN----V 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  78 RERR--LGYLVQE-GVLFPHLTVYRNIAYGLGNgKGRTAQE-RQRIEAMLELTGISELAGRYPHELSGGQQQRVALARAL 153
Cdd:PRK13650   77 WDIRhkIGMVFQNpDNQFVGATVEDDVAFGLEN-KGIPHEEmKERVNEALELVGMQDFKEREPARLSGGQKQRVAIAGAV 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 154 APDPELILLDEPFSALDEQLR-------RQIREDmiaalraNGKSAVFVSHDREE-ALqyADRIAVMKQGRILQTASPHE 225
Cdd:PRK13650  156 AMRPKIIILDEATSMLDPEGRleliktiKGIRDD-------YQMTVISITHDLDEvAL--SDRVLVMKNGQVESTSTPRE 226


                  ....*....
gi 1067578656 226 LYRQPADLD 234
Cdd:PRK13650  227 LFSRGNDLL 235
type_I_sec_PrtD TIGR01842
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ...
 15-218 5.67e-38

type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 200134 [Multi-domain]  Cd Length: 544  Bit Score: 142.49  E-value: 5.67e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  15 QNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsKNTNLPVRERRLGYLVQEGVLFPH 94
Cdd:TIGR01842 329 GKKPTLRGISFSLQAGEALAIIGPSGSGKSTLARLIVGIWPPTSGSVRLDGADL--KQWDRETFGKHIGYLPQDVELFPG 406

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  95 lTVYRNIAYglgngKGRTAQERQRIEAMlELTGISELAGRYPH-----------ELSGGQQQRVALARALAPDPELILLD 163
Cdd:TIGR01842 407 -TVAENIAR-----FGENADPEKIIEAA-KLAGVHELILRLPDgydtvigpggaTLSGGQRQRIALARALYGDPKLVVLD 479

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1067578656 164 EPFSALDEQLRRQIREDMIaALRANGKSAVFVSHdREEALQYADRIAVMKQGRIL 218
Cdd:TIGR01842 480 EPNSNLDEEGEQALANAIK-ALKARGITVVVITH-RPSLLGCVDKILVLQDGRIA 532
nikE PRK10419
nickel ABC transporter ATP-binding protein NikE;
5-221 1.33e-37

nickel ABC transporter ATP-binding protein NikE;


Pssm-ID: 236689 [Multi-domain]  Cd Length: 268  Bit Score: 135.58  E-value: 1.33e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQNTP---------VLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNTNL 75
Cdd:PRK10419    4 LNVSGLSHHYAHGGlsgkhqhqtVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEPLAKLNRAQ 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  76 PVRERRLGYLV-QE--GVLFPHLTVYRNIAYGLGNGKGRTAQERQ-RIEAMLELTGIS-ELAGRYPHELSGGQQQRVALA 150
Cdd:PRK10419   84 RKAFRRDIQMVfQDsiSAVNPRKTVREIIREPLRHLLSLDKAERLaRASEMLRAVDLDdSVLDKRPPQLSGGQLQRVCLA 163

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1067578656 151 RALAPDPELILLDEPFSALDEQLRRQIReDMIAALRANGKSA-VFVSHDREEALQYADRIAVMKQGRILQTA 221
Cdd:PRK10419  164 RALAVEPKLLILDEAVSNLDLVLQAGVI-RLLKKLQQQFGTAcLFITHDLRLVERFCQRVMVMDNGQIVETQ 234
lolD PRK11629
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
5-219 4.71e-37

lipoprotein-releasing ABC transporter ATP-binding protein LolD;


Pssm-ID: 183244 [Multi-domain]  Cd Length: 233  Bit Score: 133.40  E-value: 4.71e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQN----TPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTI--FSKNTNLPVR 78
Cdd:PRK11629    6 LQCDNLCKRYQEgsvqTDVLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMskLSSAAKAELR 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  79 ERRLGYLVQEGVLFPHLTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPE 158
Cdd:PRK11629   86 NQKLGFIYQFHHLLPDFTALENVAMPLLIGKKKPAEINSRALEMLAAVGLEHRANHRPSELSGGERQRVAIARALVNNPR 165

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1067578656 159 LILLDEPFSALDEQLRRQIREDMIAALRANGKSAVFVSHDreeaLQYADRIA---VMKQGRILQ 219
Cdd:PRK11629  166 LVLADEPTGNLDARNADSIFQLLGELNRLQGTAFLVVTHD----LQLAKRMSrqlEMRDGRLTA 225
PhnL COG4778
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ...
 1-216 1.14e-36

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];


Pssm-ID: 443809 [Multi-domain]  Cd Length: 229  Bit Score: 132.17  E-value: 1.14e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   1 MTAALHIGHLSKSF----QNT---PVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEI------------ 61
Cdd:COG4778     1 MTTLLEVENLSKTFtlhlQGGkrlPVLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSIlvrhdggwvdla 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  62 SLSGKTIfskntnLPVRERRLGYLVQegvlF----PHLTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGISE-LAGRYP 136
Cdd:COG4778    81 QASPREI------LALRRRTIGYVSQ----FlrviPRVSALDVVAEPLLERGVDREEARARARELLARLNLPErLWDLPP 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 137 HELSGGQQQRVALARALAPDPELILLDEPFSALDEQLRRQIREdMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGR 216
Cdd:COG4778   151 ATFSGGEQQRVNIARGFIADPPLLLLDEPTASLDAANRAVVVE-LIEEAKARGTAIIGIFHDEEVREAVADRVVDVTPFS 229
PRK14239 PRK14239
phosphate transporter ATP-binding protein; Provisional
 1-231 2.68e-36

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184585 [Multi-domain]  Cd Length: 252  Bit Score: 131.82  E-value: 2.68e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   1 MTAA-LHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCL--AGFEQPD---SGEISLSGKTIFSKNTN 74
Cdd:PRK14239    1 MTEPiLQVSDLSVYYNKKKALNSVSLDFYPNEITALIGPSGSGKSTLLRSInrMNDLNPEvtiTGSIVYNGHNIYSPRTD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  75 LPVRERRLGYLVQEGVLFPhLTVYRNIAYGLG-NGkgrtAQERQRIEAMLE--LTGIS---ELAGRYpHE----LSGGQQ 144
Cdd:PRK14239   81 TVDLRKEIGMVFQQPNPFP-MSIYENVVYGLRlKG----IKDKQVLDEAVEksLKGASiwdEVKDRL-HDsalgLSGGQQ 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 145 QRVALARALAPDPELILLDEPFSALDEQLRRQIrEDMIAALRaNGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPH 224
Cdd:PRK14239  155 QRVCIARVLATSPKIILLDEPTSALDPISAGKI-EETLLGLK-DDYTMLLVTRSMQQASRISDRTGFFLDGDLIEYNDTK 232


                  ....*..
gi 1067578656 225 ELYRQPA 231
Cdd:PRK14239  233 QMFMNPK 239
PRK10535 PRK10535
macrolide ABC transporter ATP-binding protein/permease MacB;
1-237 3.27e-36

macrolide ABC transporter ATP-binding protein/permease MacB;


Pssm-ID: 182528 [Multi-domain]  Cd Length: 648  Bit Score: 138.70  E-value: 3.27e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   1 MTAALHIGHLSKSFQN----TPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNTNLP 76
Cdd:PRK10535    1 MTALLELKDIRRSYPSgeeqVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQDVATLDADAL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  77 VRERR--LGYLVQEGVLFPHLTVYRNI---AYGLGNGKgrtAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALAR 151
Cdd:PRK10535   81 AQLRRehFGFIFQRYHLLSHLTAAQNVevpAVYAGLER---KQRLLRAQELLQRLGLEDRVEYQPSQLSGGQQQRVSIAR 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 152 ALAPDPELILLDEPFSALDEQLRRQIREdMIAALRANGKSAVFVSHDREEALQyADRIAVMKQGRILQTaSPHELYRQPA 231
Cdd:PRK10535  158 ALMNGGQVILADEPTGALDSHSGEEVMA-ILHQLRDRGHTVIIVTHDPQVAAQ-AERVIEIRDGEIVRN-PPAQEKVNVA 234


                  ....*.
gi 1067578656 232 DLDAAL 237
Cdd:PRK10535  235 GGTEPV 240
urea_trans_UrtE TIGR03410
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC ...
 5-220 7.57e-36

urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274567 [Multi-domain]  Cd Length: 230  Bit Score: 129.95  E-value: 7.57e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNTNLPVReRRLGY 84
Cdd:TIGR03410   1 LEVSNLNVYYGQSHILRGVSLEVPKGEVTCVLGRNGVGKTTLLKTLMGLLPVKSGSIRLDGEDITKLPPHERAR-AGIAY 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  85 LVQEGVLFPHLTVYRNIAYGLGNGKGRtaqERQRIEAMLELTGI-SELAGRYPHELSGGQQQRVALARALAPDPELILLD 163
Cdd:TIGR03410  80 VPQGREIFPRLTVEENLLTGLAALPRR---SRKIPDEIYELFPVlKEMLGRRGGDLSGGQQQQLAIARALVTRPKLLLLD 156

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1067578656 164 EPFSALDEQLRRQIrEDMIAALRANGKSAVFVS-HDREEALQYADRIAVMKQGRILQT 220
Cdd:TIGR03410 157 EPTEGIQPSIIKDI-GRVIRRLRAEGGMAILLVeQYLDFARELADRYYVMERGRVVAS 213
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
18-217 1.04e-35

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 135.53  E-value: 1.04e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  18 PVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNTNLPVReRRLGYL----VQEGvLFP 93
Cdd:COG1129   266 GVVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDGKPVRIRSPRDAIR-AGIAYVpedrKGEG-LVL 343

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  94 HLTVYRNIAygLGN----GKG---RTAQERQRIEAMLELTGIselagRYPH------ELSGGQQQRVALARALAPDPELI 160
Cdd:COG1129   344 DLSIRENIT--LASldrlSRGgllDRRRERALAEEYIKRLRI-----KTPSpeqpvgNLSGGNQQKVVLAKWLATDPKVL 416

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1067578656 161 LLDEPFSALDEQLRRQIREdMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRI 217
Cdd:COG1129   417 ILDEPTRGIDVGAKAEIYR-LIRELAAEGKAVIVISSELPELLGLSDRILVMREGRI 472
dppF PRK11308
dipeptide transporter ATP-binding subunit; Provisional
 20-230 1.49e-35

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 236898 [Multi-domain]  Cd Length: 327  Bit Score: 132.01  E-value: 1.49e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  20 LNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNtnlPVRERRLGYLVQ------EGVLFP 93
Cdd:PRK11308   31 LDGVSFTLERGKTLAVVGESGCGKSTLARLLTMIETPTGGELYYQGQDLLKAD---PEAQKLLRQKIQivfqnpYGSLNP 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  94 HLTVYRNIAYGLG-NGKGRTAQERQRIEAMLELTGI-SELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDE 171
Cdd:PRK11308  108 RKKVGQILEEPLLiNTSLSAAERREKALAMMAKVGLrPEHYDRYPHMFSGGQRQRIAIARALMLDPDVVVADEPVSALDV 187

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1067578656 172 QLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQP 230
Cdd:PRK11308  188 SVQAQVLNLMMDLQQELGLSYVFISHDLSVVEHIADEVMVMYLGRCVEKGTKEQIFNNP 246
PRK13537 PRK13537
nodulation factor ABC transporter ATP-binding protein NodI;
1-226 1.71e-35

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237420 [Multi-domain]  Cd Length: 306  Bit Score: 131.08  E-value: 1.71e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   1 MTAALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNtnlPVRER 80
Cdd:PRK13537    4 SVAPIDFRNVEKRYGDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPVPSRA---RHARQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  81 RLGYLVQEGVLFPHLTVYRNIA-----YGLGngkgrTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAP 155
Cdd:PRK13537   81 RVGVVPQFDNLDPDFTVRENLLvfgryFGLS-----AAAARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARALVN 155

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1067578656 156 DPELILLDEPFSALDEQLRRQIREDMiAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHEL 226
Cdd:PRK13537  156 DPDVLVLDEPTTGLDPQARHLMWERL-RSLLARGKTILLTTHFMEEAERLCDRLCVIEEGRKIAEGAPHAL 225
ABCC_Hemolysin cd03252
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...
 19-229 4.45e-35

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.


Pssm-ID: 213219 [Multi-domain]  Cd Length: 237  Bit Score: 128.37  E-value: 4.45e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  19 VLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNTNLpvRERRLGYLVQEGVLFpHLTVY 98
Cdd:cd03252    17 ILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLALADPAW--LRRQVGVVLQENVLF-NRSIR 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  99 RNIAYGlgngkgRTAQERQRIEAMLELTG----ISEL-------AGRYPHELSGGQQQRVALARALAPDPELILLDEPFS 167
Cdd:cd03252    94 DNIALA------DPGMSMERVIEAAKLAGahdfISELpegydtiVGEQGAGLSGGQRQRIAIARALIHNPRILIFDEATS 167

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1067578656 168 ALDEQLRRQIREDMIAALRanGKSAVFVSHdREEALQYADRIAVMKQGRILQTASPHELYRQ 229
Cdd:cd03252   168 ALDYESEHAIMRNMHDICA--GRTVIIIAH-RLSTVKNADRIIVMEKGRIVEQGSHDELLAE 226
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 9-200 4.61e-35

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 134.04  E-value: 4.61e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   9 HLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTifskntnlpvrerRLGYLVQE 88
Cdd:COG0488     3 NLSKSFGGRPLLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSIPKGL-------------RIGYLPQE 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  89 GVLFPHLTVYRNIAYGLG---------------NGKGRTAQERQ-----------------RIEAMLELTGISELAGRYP 136
Cdd:COG0488    70 PPLDDDLTVLDTVLDGDAelraleaeleeleakLAEPDEDLERLaelqeefealggweaeaRAEEILSGLGFPEEDLDRP 149

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1067578656 137 -HELSGGQQQRVALARALAPDPELILLDEPFSALDeqlrrqirEDMIAALR---ANGKSAV-FVSHDRE 200
Cdd:COG0488   150 vSELSGGWRRRVALARALLSEPDLLLLDEPTNHLD--------LESIEWLEeflKNYPGTVlVVSHDRY 210
PRK11831 PRK11831
phospholipid ABC transporter ATP-binding protein MlaF;
16-271 9.11e-35

phospholipid ABC transporter ATP-binding protein MlaF;


Pssm-ID: 236997 [Multi-domain]  Cd Length: 269  Bit Score: 128.34  E-value: 9.11e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  16 NTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTI--FSKNTNLPVReRRLGYLVQEGVLFP 93
Cdd:PRK11831   19 NRCIFDNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGENIpaMSRSRLYTVR-KRMSMLFQSGALFT 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  94 HLTVYRNIAYGLGNGKGRTAQERQRIEAM-LELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDEq 172
Cdd:PRK11831   98 DMNVFDNVAYPLREHTQLPAPLLHSTVMMkLEAVGLRGAAKLMPSELSGGMARRAALARAIALEPDLIMFDEPFVGQDP- 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 173 LRRQIREDMIAAL-RANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELyRQPADLDAALFIgegivfpaalna 251
Cdd:PRK11831  177 ITMGVLVKLISELnSALGVTCVVVSHDVPEVLSIADHAYIVADKKIVAHGSAQAL-QANPDPRVRQFL------------ 243

                         250       260
                  ....*....|....*....|
gi 1067578656 252 DGTADCrlgrlPVQSGAPAG 271
Cdd:PRK11831  244 DGIADG-----PVPFRYPAG 258
ABCC_MsbA cd03251
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ...
 17-229 9.42e-35

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213218 [Multi-domain]  Cd Length: 234  Bit Score: 127.35  E-value: 9.42e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  17 TPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsKNTNLPVRERRLGYLVQEGVLFpHLT 96
Cdd:cd03251    15 PPVLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHDV--RDYTLASLRRQIGLVSQDVFLF-NDT 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  97 VYRNIAYGlgngkgRTAQERQRIEAMLELTGISELAGRYPH-----------ELSGGQQQRVALARALAPDPELILLDEP 165
Cdd:cd03251    92 VAENIAYG------RPGATREEVEEAARAANAHEFIMELPEgydtvigergvKLSGGQRQRIAIARALLKDPPILILDEA 165

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1067578656 166 FSALDEQLRRQIREDMIAALRanGKSAVFVSHdREEALQYADRIAVMKQGRILQTASPHELYRQ 229
Cdd:cd03251   166 TSALDTESERLVQAALERLMK--NRTTFVIAH-RLSTIENADRIVVLEDGKIVERGTHEELLAQ 226
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 9-217 1.14e-34

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 132.88  E-value: 1.14e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   9 HLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLsGKTIfskntnlpvrerRLGYLVQE 88
Cdd:COG0488   320 GLSKSYGDKTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVKL-GETV------------KIGYFDQH 386

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  89 G-VLFPHLTVYRNIAYGLGNGKGRTAqeRQRIEAMLeLTGisELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFS 167
Cdd:COG0488   387 QeELDPDKTVLDELRDGAPGGTEQEV--RGYLGRFL-FSG--DDAFKPVGVLSGGEKARLALAKLLLSPPNVLLLDEPTN 461

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1067578656 168 ALDEQLRRQIrEDmiaALRA-NGkSAVFVSHDRE--EALqyADRIAVMKQGRI 217
Cdd:COG0488   462 HLDIETLEAL-EE---ALDDfPG-TVLLVSHDRYflDRV--ATRILEFEDGGV 507
ABCC_Glucan_exporter_like cd03254
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ...
 16-226 3.50e-34

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213221 [Multi-domain]  Cd Length: 229  Bit Score: 125.42  E-value: 3.50e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  16 NTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsKNTNLPVRERRLGYLVQEGVLFPHl 95
Cdd:cd03254    15 KKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDI--RDISRKSLRSMIGVVLQDTFLFSG- 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  96 TVYRNIAYglgngkGRTAQERQRIEAMLELTGISELAGRYP-----------HELSGGQQQRVALARALAPDPELILLDE 164
Cdd:cd03254    92 TIMENIRL------GRPNATDEEVIEAAKEAGAHDFIMKLPngydtvlgengGNLSQGERQLLAIARAMLRDPKILILDE 165

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1067578656 165 PFSALDEQLRRQIREDMIAALraNGKSAVFVSHdREEALQYADRIAVMKQGRILQTASPHEL 226
Cdd:cd03254   166 ATSNIDTETEKLIQEALEKLM--KGRTSIIIAH-RLSTIKNADKILVLDDGKIIEEGTHDEL 224
cbiO PRK13641
energy-coupling factor transporter ATPase;
20-230 6.19e-34

energy-coupling factor transporter ATPase;


Pssm-ID: 237456 [Multi-domain]  Cd Length: 287  Bit Score: 126.48  E-value: 6.19e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  20 LNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSK--NTNLPVRERRLGYLVQ--EGVLFPHl 95
Cdd:PRK13641   23 LDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHITPEtgNKNLKKLRKKVSLVFQfpEAQLFEN- 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  96 TVYRNIAYGLGNgKGRTAQErQRIEAM--LELTGISE-LAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDEQ 172
Cdd:PRK13641  102 TVLKDVEFGPKN-FGFSEDE-AKEKALkwLKKVGLSEdLISKSPFELSGGQMRRVAIAGVMAYEPEILCLDEPAAGLDPE 179

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1067578656 173 LRRQIREDMIAALRAnGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQP 230
Cdd:PRK13641  180 GRKEMMQLFKDYQKA-GHTVILVTHNMDDVAEYADDVLVLEHGKLIKHASPKEIFSDK 236
PRK10895 PRK10895
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
 3-226 1.01e-33

lipopolysaccharide ABC transporter ATP-binding protein; Provisional


Pssm-ID: 182817 [Multi-domain]  Cd Length: 241  Bit Score: 124.62  E-value: 1.01e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   3 AALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRERR- 81
Cdd:PRK10895    2 ATLTAKNLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDI----SLLPLHARAr 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  82 --LGYLVQEGVLFPHLTVYRNIAYGLGNGKGRTAQERQ-RIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPE 158
Cdd:PRK10895   78 rgIGYLPQEASIFRRLSVYDNLMAVLQIRDDLSAEQREdRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPK 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1067578656 159 LILLDEPFSALDEQLRRQIREdMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHEL 226
Cdd:PRK10895  158 FILLDEPFAGVDPISVIDIKR-IIEHLRDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGTPTEI 224
cbiO PRK13646
energy-coupling factor transporter ATPase;
15-229 1.49e-33

energy-coupling factor transporter ATPase;


Pssm-ID: 184205 [Multi-domain]  Cd Length: 286  Bit Score: 125.66  E-value: 1.49e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  15 QNTP----VLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNTN---LPVReRRLGYLVQ 87
Cdd:PRK13646   14 KGTPyehqAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITITHKTKDkyiRPVR-KRIGMVFQ 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  88 --EGVLFPHlTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGIS-ELAGRYPHELSGGQQQRVALARALAPDPELILLDE 164
Cdd:PRK13646   93 fpESQLFED-TVEREIIFGPKNFKMNLDEVKNYAHRLLMDLGFSrDVMSQSPFQMSGGQMRKIAIVSILAMNPDIIVLDE 171

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1067578656 165 PFSALDEQLRRQIREdMIAALRA-NGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQ 229
Cdd:PRK13646  172 PTAGLDPQSKRQVMR-LLKSLQTdENKTIILVSHDMNEVARYADEVIVMKEGSIVSQTSPKELFKD 236
TagH COG1134
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...
 1-229 2.65e-33

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440749 [Multi-domain]  Cd Length: 245  Bit Score: 123.65  E-value: 2.65e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   1 MTAALHIGHLSKSFQ-----------------NTP-----VLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDS 58
Cdd:COG1134     1 MSSMIEVENVSKSYRlyhepsrslkelllrrrRTRreefwALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  59 GEISLSGktifskntnlpvrerRLGYLVQEGVLF-PHLTVYRNI-----AYGLgngkgRTAQERQRIEAMLELTGIsela 132
Cdd:COG1134    81 GRVEVNG---------------RVSALLELGAGFhPELTGRENIylngrLLGL-----SRKEIDEKFDEIVEFAEL---- 136

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 133 GRYPHE----LSGGQQQRVALARALAPDPELILLDEPFSALDEQLRRQIReDMIAALRANGKSAVFVSHDREEALQYADR 208
Cdd:COG1134   137 GDFIDQpvktYSSGMRARLAFAVATAVDPDILLVDEVLAVGDAAFQKKCL-ARIRELRESGRTVIFVSHSMGAVRRLCDR 215

                         250       260
                  ....*....|....*....|....
gi 1067578656 209 IAVMKQGRILQTASPHE---LYRQ 229
Cdd:COG1134   216 AIWLEKGRLVMDGDPEEviaAYEA 239
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
 1-226 3.31e-33

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 128.63  E-value: 3.31e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   1 MTAALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNtnlPVRER 80
Cdd:PRK15439    8 APPLLCARSISKQYSGVEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPCARLT---PAKAH 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  81 RLG-YLV-QEGVLFPHLTVYRNIAYGLgngkGRTAQERQRIEAMLELTGIS----ELAGryphELSGGQQQRVALARALA 154
Cdd:PRK15439   85 QLGiYLVpQEPLLFPNLSVKENILFGL----PKRQASMQKMKQLLAALGCQldldSSAG----SLEVADRQIVEILRGLM 156

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1067578656 155 PDPELILLDEPFSALD----EQLRRQIRedmiaALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHEL 226
Cdd:PRK15439  157 RDSRILILDEPTASLTpaetERLFSRIR-----ELLAQGVGIVFISHKLPEIRQLADRISVMRDGTIALSGKTADL 227
CydD TIGR02857
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ...
 17-212 6.02e-33

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD


Pssm-ID: 274323 [Multi-domain]  Cd Length: 529  Bit Score: 128.17  E-value: 6.02e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  17 TPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsKNTNLPVRERRLGYLVQEGVLFPHlT 96
Cdd:TIGR02857 335 RPALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVPL--ADADADSWRDQIAWVPQHPFLFAG-T 411

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  97 VYRNIAYGLGNGKGRTAQERQRIEAMLELT-----GISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDE 171
Cdd:TIGR02857 412 IAENIRLARPDASDAEIREALERAGLDEFVaalpqGLDTPIGEGGAGLSGGQAQRLALARAFLRDAPLLLLDEPTAHLDA 491

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1067578656 172 QLRRQIREDMIAAlrANGKSAVFVSHDREEALQyADRIAVM 212
Cdd:TIGR02857 492 ETEAEVLEALRAL--AQGRTVLLVTHRLALAAL-ADRIVVL 529
cbiO PRK13639
cobalt transporter ATP-binding subunit; Provisional
 17-236 2.10e-32

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184199 [Multi-domain]  Cd Length: 275  Bit Score: 122.11  E-value: 2.10e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  17 TPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTI-FSKNTNLPVReRRLGYLVQ--EGVLF- 92
Cdd:PRK13639   15 TEALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEPIkYDKKSLLEVR-KTVGIVFQnpDDQLFa 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  93 PhlTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDEQ 172
Cdd:PRK13639   94 P--TVEEDVAFGPLNLGLSKEEVEKRVKEALKAVGMEGFENKPPHHLSGGQKKRVAIAGILAMKPEIIVLDEPTSGLDPM 171

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1067578656 173 LRRQIREdMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPADLDAA 236
Cdd:PRK13639  172 GASQIMK-LLYDLNKEGITIIISTHDVDLVPVYADKVYVMSDGKIIKEGTPKEVFSDIETIRKA 234
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 4-226 2.79e-32

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 125.91  E-value: 2.79e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   4 ALHIGHLS-KSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRERR- 81
Cdd:COG3845   257 VLEVENLSvRDDRGVPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRLDGEDI----TGLSPRERRr 332

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  82 --LGYLVQE----GvLFPHLTVYRNIA-----------YGLGNGKGRTAQERQRIEAM-LELTGISELAGRypheLSGGQ 143
Cdd:COG3845   333 lgVAYIPEDrlgrG-LVPDMSVAENLIlgryrrppfsrGGFLDRKAIRAFAEELIEEFdVRTPGPDTPARS----LSGGN 407

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 144 QQRVALARALAPDPELILLDEPFSALD----EQLRRQIREdmiaaLRANGKSAVFVSHDREEALQYADRIAVMKQGRILQ 219
Cdd:COG3845   408 QQKVILARELSRDPKLLIAAQPTRGLDvgaiEFIHQRLLE-----LRDAGAAVLLISEDLDEILALSDRIAVMYEGRIVG 482


                  ....*..
gi 1067578656 220 TASPHEL 226
Cdd:COG3845   483 EVPAAEA 489
PhnK COG1101
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 5-217 2.90e-32

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 440718 [Multi-domain]  Cd Length: 264  Bit Score: 121.35  E-value: 2.90e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSF-QNTP----VLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPV-- 77
Cdd:COG1101     2 LELKNLSKTFnPGTVnekrALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGKDV----TKLPEyk 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  78 RERRLGYLVQEGVL--FPHLTVYRNIAYGLGNGKGR------TAQERQRIEAMLELTGISeLAGRYPHE---LSGGQQQR 146
Cdd:COG1101    78 RAKYIGRVFQDPMMgtAPSMTIEENLALAYRRGKRRglrrglTKKRRELFRELLATLGLG-LENRLDTKvglLSGGQRQA 156

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1067578656 147 VALARALAPDPELILLDEPFSALD--------EQLRRQIREDMIAALrangksavFVSHDREEALQYADRIAVMKQGRI 217
Cdd:COG1101   157 LSLLMATLTKPKLLLLDEHTAALDpktaalvlELTEKIVEENNLTTL--------MVTHNMEQALDYGNRLIMMHEGRI 227
PRK15079 PRK15079
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
 21-230 3.14e-32

oligopeptide ABC transporter ATP-binding protein OppF; Provisional


Pssm-ID: 185037 [Multi-domain]  Cd Length: 331  Bit Score: 122.89  E-value: 3.14e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  21 NDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfSKNTNLPVRERR--LGYLVQEGV--LFPHLT 96
Cdd:PRK15079   38 DGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAWLGKDL-LGMKDDEWRAVRsdIQMIFQDPLasLNPRMT 116

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  97 VYRNIAYGLgngkgRT------AQE-RQRIEAMLELTGI-SELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSA 168
Cdd:PRK15079  117 IGEIIAEPL-----RTyhpklsRQEvKDRVKAMMLKVGLlPNLINRYPHEFSGGQCQRIGIARALILEPKLIICDEPVSA 191

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1067578656 169 LDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQP 230
Cdd:PRK15079  192 LDVSIQAQVVNLLQQLQREMGLSLIFIAHDLAVVKHISDRVLVMYLGHAVELGTYDEVYHNP 253
ABCC_MRP_domain1 cd03250
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ...
 11-216 5.25e-32

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213217 [Multi-domain]  Cd Length: 204  Bit Score: 119.11  E-value: 5.25e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  11 SKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGktifskntnlpvrerRLGYLVQEGV 90
Cdd:cd03250    12 SGEQETSFTLKDINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPG---------------SIAYVSQEPW 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  91 LFPhLTVYRNIAYGLgngkgRTAQERQR--IEA--------MLE---LT-----GISelagrypheLSGGQQQRVALARA 152
Cdd:cd03250    77 IQN-GTIRENILFGK-----PFDEERYEkvIKAcalepdleILPdgdLTeigekGIN---------LSGGQKQRISLARA 141

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1067578656 153 LAPDPELILLDEPFSALDEQLRRQIREDMIAALRANGKSAVFVSHdREEALQYADRIAVMKQGR 216
Cdd:cd03250   142 VYSDADIYLLDDPLSAVDAHVGRHIFENCILGLLLNNKTRILVTH-QLQLLPHADQIVVLDNGR 204
cbiO PRK13640
energy-coupling factor transporter ATPase;
4-252 5.74e-32

energy-coupling factor transporter ATPase;


Pssm-ID: 184200 [Multi-domain]  Cd Length: 282  Bit Score: 121.06  E-value: 5.74e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   4 ALHIGHLSKSFQNT--PVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGE---ISLSGKTIFSKnTNLPVR 78
Cdd:PRK13640    5 IVEFKHVSFTYPDSkkPALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLLPDDNPnskITVDGITLTAK-TVWDIR 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  79 ERrLGYLVQE-GVLFPHLTVYRNIAYGLGNgKGRTAQERQRIEA-MLELTGISELAGRYPHELSGGQQQRVALARALAPD 156
Cdd:PRK13640   84 EK-VGIVFQNpDNQFVGATVGDDVAFGLEN-RAVPRPEMIKIVRdVLADVGMLDYIDSEPANLSGGQKQRVAIAGILAVE 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 157 PELILLDEPFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQyADRIAVMKQGRILQTASPHELYRQP-----A 231
Cdd:PRK13640  162 PKIIILDESTSMLDPAGKEQILKLIRKLKKKNNLTVISITHDIDEANM-ADQVLVLDDGKLLAQGSPVEIFSKVemlkeI 240

                         250       260
                  ....*....|....*....|....*...
gi 1067578656 232 DLDAALF-------IGEGIVFPAALNAD 252
Cdd:PRK13640  241 GLDIPFVyklknklKEKGISVPQEINTE 268
btuD PRK09536
corrinoid ABC transporter ATPase; Reviewed
 5-272 7.35e-32

corrinoid ABC transporter ATPase; Reviewed


Pssm-ID: 236554 [Multi-domain]  Cd Length: 402  Bit Score: 123.41  E-value: 7.35e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRE--RRL 82
Cdd:PRK09536    4 IDVSDLSVEFGDTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDV----EALSARAasRRV 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  83 GYLVQEGVLFPHLTVYRNIAYG----LGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPE 158
Cdd:PRK09536   80 ASVPQDTSLSFEFDVRQVVEMGrtphRSRFDTWTETDRAAVERAMERTGVAQFADRPVTSLSGGERQRVLLARALAQATP 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 159 LILLDEPFSALDeqLRRQIRE-DMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQP---ADLD 234
Cdd:PRK09536  160 VLLLDEPTASLD--INHQVRTlELVRRLVDDGKTAVAAIHDLDLAARYCDELVLLADGRVRAAGPPADVLTADtlrAAFD 237

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 1067578656 235 AALFIGEGIVFPAAL-----NADGTADCRLGRLPV-QSGAPAGT 272
Cdd:PRK09536  238 ARTAVGTDPATGAPTvtplpDPDRTEAAADTRVHVvGGGQPAAR 281
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
 20-229 7.64e-32

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 125.30  E-value: 7.64e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  20 LNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNTNLPVRER-----RLGYLVQEGVLFPH 94
Cdd:TIGR03269 300 VDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNVRVGDEWVDMTKPGPDGRgrakrYIGILHQEYDLYPH 379

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  95 LTVYRNI--AYGLgngkgRTAQERQRIEAM--LELTGISE-----LAGRYPHELSGGQQQRVALARALAPDPELILLDEP 165
Cdd:TIGR03269 380 RTVLDNLteAIGL-----ELPDELARMKAVitLKMVGFDEekaeeILDKYPDELSEGERHRVALAQVLIKEPRIVILDEP 454

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1067578656 166 FSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQ 229
Cdd:TIGR03269 455 TGTMDPITKVDVTHSILKAREEMEQTFIIVSHDMDFVLDVCDRAALMRDGKIVKIGDPEEIVEE 518
PRK13536 PRK13536
nodulation factor ABC transporter ATP-binding protein NodI;
2-226 1.37e-31

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237419 [Multi-domain]  Cd Length: 340  Bit Score: 121.48  E-value: 1.37e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   2 TAALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfskntnlPVRER- 80
Cdd:PRK13536   39 TVAIDLAGVSKSYGDKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLGVPV-------PARARl 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  81 ---RLGYLVQEGVLFPHLTVYRN-IAYGLGNGKgRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPD 156
Cdd:PRK13536  112 araRIGVVPQFDNLDLEFTVRENlLVFGRYFGM-STREIEAVIPSLLEFARLESKADARVSDLSGGMKRRLTLARALIND 190

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 157 PELILLDEPFSALDEQLRRQIREDMiAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHEL 226
Cdd:PRK13536  191 PQLLILDEPTTGLDPHARHLIWERL-RSLLARGKTILLTTHFMEEAERLCDRLCVLEAGRKIAEGRPHAL 259
PRK10247 PRK10247
putative ABC transporter ATP-binding protein YbbL; Provisional
 2-209 1.50e-31

putative ABC transporter ATP-binding protein YbbL; Provisional


Pssm-ID: 182331 [Multi-domain]  Cd Length: 225  Bit Score: 118.66  E-value: 1.50e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   2 TAALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRERR 81
Cdd:PRK10247    5 SPLLQLQNVGYLAGDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDI----STLKPEIYR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  82 --LGYLVQEGVLFPHlTVYRNIA--YGLGNgkgrTAQERQRIEAMLELTGISE-LAGRYPHELSGGQQQRVALARALAPD 156
Cdd:PRK10247   81 qqVSYCAQTPTLFGD-TVYDNLIfpWQIRN----QQPDPAIFLDDLERFALPDtILTKNIAELSGGEKQRISLIRNLQFM 155

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1067578656 157 PELILLDEPFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEaLQYADRI 209
Cdd:PRK10247  156 PKVLLLDEITSALDESNKHNVNEIIHRYVREQNIAVLWVTHDKDE-INHADKV 207
ABC_KpsT_Wzt cd03220
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...
 19-217 3.01e-31

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.


Pssm-ID: 213187 [Multi-domain]  Cd Length: 224  Bit Score: 117.63  E-value: 3.01e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  19 VLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGktifskntnlpvrerRLGYLVQEGVLF-PHLTV 97
Cdd:cd03220    37 ALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVTVRG---------------RVSSLLGLGGGFnPELTG 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  98 YRNIAYglgNG--KGRTAQE-RQRIEAMLELTGIselaGRYPHE----LSGGQQQRVALARALAPDPELILLDEPFSALD 170
Cdd:cd03220   102 RENIYL---NGrlLGLSRKEiDEKIDEIIEFSEL----GDFIDLpvktYSSGMKARLAFAIATALEPDILLIDEVLAVGD 174

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1067578656 171 EQLRRQIREdMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRI 217
Cdd:cd03220   175 AAFQEKCQR-RLRELLKQGKTVILVSHDPSSIKRLCDRALVLEKGKI 220
cbiO PRK13636
cobalt transporter ATP-binding subunit; Provisional
 17-227 4.23e-31

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184196 [Multi-domain]  Cd Length: 283  Bit Score: 118.80  E-value: 4.23e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  17 TPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTI-FSKNTNLPVRERrLGYLVQ--EGVLFP 93
Cdd:PRK13636   19 THALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKPIdYSRKGLMKLRES-VGMVFQdpDNQLFS 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  94 hLTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDEQL 173
Cdd:PRK13636   98 -ASVYQDVSFGAVNLKLPEDEVRKRVDNALKRTGIEHLKDKPTHCLSFGQKKRVAIAGVLVMEPKVLVLDEPTAGLDPMG 176

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1067578656 174 RRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELY 227
Cdd:PRK13636  177 VSEIMKLLVEMQKELGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQGNPKEVF 230
PRK13651 PRK13651
cobalt transporter ATP-binding subunit; Provisional
 10-225 5.07e-31

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184210 [Multi-domain]  Cd Length: 305  Bit Score: 119.04  E-value: 5.07e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  10 LSKSF-QNTP----VLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEIS---------------------- 62
Cdd:PRK13651    8 IVKIFnKKLPtelkALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIEwifkdeknkkktkekekvlekl 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  63 LSGKTIFSKNTNLPVRERRLGYLVQ--EGVLFPHlTVYRNIAYG---LGNGKgrtAQERQRIEAMLELTGISE-LAGRYP 136
Cdd:PRK13651   88 VIQKTRFKKIKKIKEIRRRVGVVFQfaEYQLFEQ-TIEKDIIFGpvsMGVSK---EEAKKRAAKYIELVGLDEsYLQRSP 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 137 HELSGGQQQRVALARALAPDPELILLDEPFSALDEQLRRQIREdMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGR 216
Cdd:PRK13651  164 FELSGGQKRRVALAGILAMEPDFLVFDEPTAGLDPQGVKEILE-IFDNLNKQGKTIILVTHDLDNVLEWTKRTIFFKDGK 242


                  ....*....
gi 1067578656 217 ILQTASPHE 225
Cdd:PRK13651  243 IIKDGDTYD 251
PRK14267 PRK14267
phosphate ABC transporter ATP-binding protein; Provisional
 1-230 6.69e-31

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184596 [Multi-domain]  Cd Length: 253  Bit Score: 117.64  E-value: 6.69e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   1 MTAALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGF-----EQPDSGEISLSGKTIFSKNTNl 75
Cdd:PRK14267    1 MKFAIETVNLRVYYGSNHVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLlelneEARVEGEVRLFGRNIYSPDVD- 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  76 PVRERR-LGYLVQEGVLFPHLTVYRNIAYGLG-NGKGRTAQE-RQRIEAMLELTGI-SELAGR---YPHELSGGQQQRVA 148
Cdd:PRK14267   80 PIEVRReVGMVFQYPNPFPHLTIYDNVAIGVKlNGLVKSKKElDERVEWALKKAALwDEVKDRlndYPSNLSGGQRQRLV 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 149 LARALAPDPELILLDEPFSALDEQLRRQIrEDMIAALRaNGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYR 228
Cdd:PRK14267  160 IARALAMKPKILLMDEPTANIDPVGTAKI-EELLFELK-KEYTIVLVTHSPAQAARVSDYVAFLYLGKLIEVGPTRKVFE 237


                  ..
gi 1067578656 229 QP 230
Cdd:PRK14267  238 NP 239
PRK09984 PRK09984
phosphonate ABC transporter ATP-binding protein;
1-226 7.54e-31

phosphonate ABC transporter ATP-binding protein;


Pssm-ID: 182182 [Multi-domain]  Cd Length: 262  Bit Score: 117.81  E-value: 7.54e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   1 MTAALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDS---GEISLSGKTIfSKNTNLP- 76
Cdd:PRK09984    1 MQTIIRVEKLAKTFNQHQALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLITGDKsagSHIELLGRTV-QREGRLAr 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  77 -VRERR--LGYLVQEGVLFPHLTVYRNIAYG-LGNG-------KGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQ 145
Cdd:PRK09984   80 dIRKSRanTGYIFQQFNLVNRLSVLENVLIGaLGSTpfwrtcfSWFTREQKQRALQALTRVGMVHFAHQRVSTLSGGQQQ 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 146 RVALARALAPDPELILLDEPFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHE 225
Cdd:PRK09984  160 RVAIARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNDGITVVVTLHQVDYALRYCERIVALRQGHVFYDGSSQQ 239


                  .
gi 1067578656 226 L 226
Cdd:PRK09984  240 F 240
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 7-223 1.02e-30

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 123.59  E-value: 1.02e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656    7 IGHLSKSFQ--NTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfskNTNLPVRERRLGY 84
Cdd:TIGR01257  931 VKNLVKIFEpsGRPAVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKDI---ETNLDAVRQSLGM 1007

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   85 LVQEGVLFPHLTVYRNIAYgLGNGKGRTAQERQ-RIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLD 163
Cdd:TIGR01257 1008 CPQHNILFHHLTVAEHILF-YAQLKGRSWEEAQlEMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLD 1086

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  164 EPFSALDEQLRRQIReDMIAALRAnGKSAVFVSHDREEALQYADRIAVMKQGRILQTASP 223
Cdd:TIGR01257 1087 EPTSGVDPYSRRSIW-DLLLKYRS-GRTIIMSTHHMDEADLLGDRIAIISQGRLYCSGTP 1144
cbiO PRK13631
cobalt transporter ATP-binding subunit; Provisional
 5-231 1.13e-30

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237451 [Multi-domain]  Cd Length: 320  Bit Score: 118.80  E-value: 1.13e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSF-QNTP----VLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISL-----SGKTIFSKNTN 74
Cdd:PRK13631   22 LRVKNLYCVFdEKQEnelvALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIQVgdiyiGDKKNNHELIT 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  75 LPV-----RERRLGYLVQEGVLFPHL-----TVYRNIAYG---LGNGKGRTaqeRQRIEAMLELTGISE-LAGRYPHELS 140
Cdd:PRK13631  102 NPYskkikNFKELRRRVSMVFQFPEYqlfkdTIEKDIMFGpvaLGVKKSEA---KKLAKFYLNKMGLDDsYLERSPFGLS 178

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 141 GGQQQRVALARALAPDPELILLDEPFSALDEQLRRQIReDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQT 220
Cdd:PRK13631  179 GGQKRRVAIAGILAIQPEILIFDEPTAGLDPKGEHEMM-QLILDAKANNKTVFVITHTMEHVLEVADEVIVMDKGKILKT 257

                         250
                  ....*....|.
gi 1067578656 221 ASPHELYRQPA 231
Cdd:PRK13631  258 GTPYEIFTDQH 268
PRK10908 PRK10908
cell division ATP-binding protein FtsE;
9-217 1.43e-30

cell division ATP-binding protein FtsE;


Pssm-ID: 182829 [Multi-domain]  Cd Length: 222  Bit Score: 115.74  E-value: 1.43e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   9 HLSKSF-QNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFS-KNTNLPVRERRLGYLV 86
Cdd:PRK10908    6 HVSKAYlGGRQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITRlKNREVPFLRRQIGMIF 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  87 QEGVLFPHLTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPF 166
Cdd:PRK10908   86 QDHHLLMDRTVYDNVAIPLIIAGASGDDIRRRVSAALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKPAVLLADEPT 165

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1067578656 167 SALDEQLRRQIREdMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRI 217
Cdd:PRK10908  166 GNLDDALSEGILR-LFEEFNRVGVTVLMATHDIGLISRRSYRMLTLSDGHL 215
MsbA_lipidA TIGR02203
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ...
 18-226 1.66e-30

lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]


Pssm-ID: 131258 [Multi-domain]  Cd Length: 571  Bit Score: 121.75  E-value: 1.66e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  18 PVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsKNTNLPVRERRLGYLVQEGVLFPHlTV 97
Cdd:TIGR02203 346 PALDSISLVIEPGETVALVGRSGSGKSTLVNLIPRFYEPDSGQILLDGHDL--ADYTLASLRRQVALVSQDVVLFND-TI 422

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  98 YRNIAYGLGNGKGRtaqerQRIEAMLELTGISELAGRYPH-----------ELSGGQQQRVALARALAPDPELILLDEPF 166
Cdd:TIGR02203 423 ANNIAYGRTEQADR-----AEIERALAAAYAQDFVDKLPLgldtpigengvLLSGGQRQRLAIARALLKDAPILILDEAT 497

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1067578656 167 SALDEQLRRQIRedmiAALRA--NGKSAVFVSHdREEALQYADRIAVMKQGRILQTASPHEL 226
Cdd:TIGR02203 498 SALDNESERLVQ----AALERlmQGRTTLVIAH-RLSTIEKADRIVVMDDGRIVERGTHNEL 554
cbiO PRK13649
energy-coupling factor transporter ATPase;
18-229 3.22e-30

energy-coupling factor transporter ATPase;


Pssm-ID: 184208 [Multi-domain]  Cd Length: 280  Bit Score: 116.38  E-value: 3.22e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  18 PVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNTNLPVRERR--LGYLVQ--EGVLFP 93
Cdd:PRK13649   21 RALFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLITSTSKNKDIKQIRkkVGLVFQfpESQLFE 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  94 HlTVYRNIAYGLGNgKGRTAQERQRI-EAMLELTGISE-LAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDE 171
Cdd:PRK13649  101 E-TVLKDVAFGPQN-FGVSQEEAEALaREKLALVGISEsLFEKNPFELSGGQMRRVAIAGILAMEPKILVLDEPTAGLDP 178

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1067578656 172 QLRRQIReDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQ 229
Cdd:PRK13649  179 KGRKELM-TLFKKLHQSGMTIVLVTHLMDDVANYADFVYVLEKGKLVLSGKPKDIFQD 235
cbiO PRK13643
energy-coupling factor transporter ATPase;
16-229 3.47e-30

energy-coupling factor transporter ATPase;


Pssm-ID: 184203 [Multi-domain]  Cd Length: 288  Bit Score: 116.76  E-value: 3.47e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  16 NTP----VLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNTNL---PVReRRLGYLVQ- 87
Cdd:PRK13643   14 NSPfasrALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVGDIVVSSTSKQKeikPVR-KKVGVVFQf 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  88 -EGVLFPHlTVYRNIAYGLGNgKGRTAQERQRIEA-MLELTGIS-ELAGRYPHELSGGQQQRVALARALAPDPELILLDE 164
Cdd:PRK13643   93 pESQLFEE-TVLKDVAFGPQN-FGIPKEKAEKIAAeKLEMVGLAdEFWEKSPFELSGGQMRRVAIAGILAMEPEVLVLDE 170

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1067578656 165 PFSALDEQLRRQIREdMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQ 229
Cdd:PRK13643  171 PTAGLDPKARIEMMQ-LFESIHQSGQTVVLVTHLMDDVADYADYVYLLEKGHIISCGTPSDVFQE 234
cbiO PRK13647
cobalt transporter ATP-binding subunit; Provisional
 17-223 3.88e-30

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237457 [Multi-domain]  Cd Length: 274  Bit Score: 115.99  E-value: 3.88e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  17 TPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfSKNTNLPVReRRLGYLVQE--GVLFPh 94
Cdd:PRK13647   18 TKALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREV-NAENEKWVR-SKVGLVFQDpdDQVFS- 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  95 LTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDEQLR 174
Cdd:PRK13647   95 STVWDDVAFGPVNMGLDKDEVERRVEEALKAVRMWDFRDKPPYHLSYGQKKRVAIAGVLAMDPDVIVLDEPMAYLDPRGQ 174

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1067578656 175 RQIREdMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASP 223
Cdd:PRK13647  175 ETLME-ILDRLHNQGKTVIVATHDVDLAAEWADQVIVLKEGRVLAEGDK 222
ABCG_EPDR cd03213
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...
 17-218 6.27e-30

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.


Pssm-ID: 213180 [Multi-domain]  Cd Length: 194  Bit Score: 113.03  E-value: 6.27e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  17 TPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAG--FEQPDSGEISLSGKTIFSKNTNlpvreRRLGYLVQEGVLFPH 94
Cdd:cd03213    22 KQLLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGrrTGLGVSGEVLINGRPLDKRSFR-----KIIGYVPQDDILHPT 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  95 LTVYRNIAYglgngkgrTAQERQrieamleltgiselagrypheLSGGQQQRVALARALAPDPELILLDEPFSALDEQLR 174
Cdd:cd03213    97 LTVRETLMF--------AAKLRG---------------------LSGGERKRVSIALELVSNPSLLFLDEPTSGLDSSSA 147

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1067578656 175 RQIREdMIAALRANGKSAVFVSHD-REEALQYADRIAVMKQGRIL 218
Cdd:cd03213   148 LQVMS-LLRRLADTGRTIICSIHQpSSEIFELFDKLLLLSQGRVI 191
bacteriocin_ABC TIGR01193
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ...
 5-226 7.29e-30

ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]


Pssm-ID: 130261 [Multi-domain]  Cd Length: 708  Bit Score: 120.61  E-value: 7.29e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQ-NTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsKNTNLPVRERRLG 83
Cdd:TIGR01193 474 IVINDVSYSYGyGSNILSDISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQARSGEILLNGFSL--KDIDRHTLRQFIN 551

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  84 YLVQEGVLFPHlTVYRNIAygLGNGKGRTAQE----------RQRIEAMLE--LTGISELAGryphELSGGQQQRVALAR 151
Cdd:TIGR01193 552 YLPQEPYIFSG-SILENLL--LGAKENVSQDEiwaaceiaeiKDDIENMPLgyQTELSEEGS----SISGGQKQRIALAR 624

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1067578656 152 ALAPDPELILLDEPFSALDEQLRRQIREDMiaaLRANGKSAVFVSHdREEALQYADRIAVMKQGRILQTASPHEL 226
Cdd:TIGR01193 625 ALLTDSKVLILDESTSNLDTITEKKIVNNL---LNLQDKTIIFVAH-RLSVAKQSDKIIVLDHGKIIEQGSHDEL 695
cbiO PRK13652
cobalt transporter ATP-binding subunit; Provisional
 16-230 1.00e-29

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 172200 [Multi-domain]  Cd Length: 277  Bit Score: 114.90  E-value: 1.00e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  16 NTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNtnlpVRERR--LGYLVQ---EGV 90
Cdd:PRK13652   16 SKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPITKEN----IREVRkfVGLVFQnpdDQI 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  91 LFPhlTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALD 170
Cdd:PRK13652   92 FSP--TVEQDIAFGPINLGLDEETVAHRVSSALHMLGLEELRDRVPHHLSGGEKKRVAIAGVIAMEPQVLVLDEPTAGLD 169

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 171 EQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQP 230
Cdd:PRK13652  170 PQGVKELIDFLNDLPETYGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVEEIFLQP 229
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
 22-230 2.04e-29

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 118.80  E-value: 2.04e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  22 DISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTI--FSKNTNLPVReRRLGYLVQE--GVLFPHLTV 97
Cdd:PRK10261  342 KVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIdtLSPGKLQALR-RDIQFIFQDpyASLDPRQTV 420

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  98 YRNI-----AYGLGNGKgrtaQERQRIEAMLELTGI-SELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDE 171
Cdd:PRK10261  421 GDSImeplrVHGLLPGK----AAAARVAWLLERVGLlPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADEAVSALDV 496

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1067578656 172 QLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQP 230
Cdd:PRK10261  497 SIRGQIINLLLDLQRDFGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGPRRAVFENP 555
livG PRK11300
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
 21-241 2.71e-29

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional


Pssm-ID: 183080 [Multi-domain]  Cd Length: 255  Bit Score: 113.16  E-value: 2.71e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  21 NDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRE-RRLGyLV---QEGVLFPHLT 96
Cdd:PRK11300   22 NNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQHI----EGLPGHQiARMG-VVrtfQHVRLFREMT 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  97 V--------YRNIAYGLGNGKGRTAQERQR-IEAM------LELTGISELAGRYPHELSGGQQQRVALARALAPDPELIL 161
Cdd:PRK11300   97 VienllvaqHQQLKTGLFSGLLKTPAFRRAeSEALdraatwLERVGLLEHANRQAGNLAYGQQRRLEIARCMVTQPEILM 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 162 LDEPFSALDEQLRRQIREdMIAALRAN-GKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPADLDAALfiG 240
Cdd:PRK11300  177 LDEPAAGLNPKETKELDE-LIAELRNEhNVTVLLIEHDMKLVMGISDRIYVVNQGTPLANGTPEEIRNNPDVIKAYL--G 253


                  .
gi 1067578656 241 E 241
Cdd:PRK11300  254 E 254
cbiO PRK13644
energy-coupling factor transporter ATPase;
17-231 2.96e-29

energy-coupling factor transporter ATPase;


Pssm-ID: 106587 [Multi-domain]  Cd Length: 274  Bit Score: 113.54  E-value: 2.96e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  17 TPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTI--FSKntnLPVRERRLGYLVQE-GVLFP 93
Cdd:PRK13644   15 TPALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGIDTgdFSK---LQGIRKLVGIVFQNpETQFV 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  94 HLTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDEQL 173
Cdd:PRK13644   92 GRTVEEDLAFGPENLCLPPIEIRKRVDRALAEIGLEKYRHRSPKTLSGGQGQCVALAGILTMEPECLIFDEVTSMLDPDS 171

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1067578656 174 RRQIREDmIAALRANGKSAVFVSHDREEaLQYADRIAVMKQGRILQTASPHELYRQPA 231
Cdd:PRK13644  172 GIAVLER-IKKLHEKGKTIVYITHNLEE-LHDADRIIVMDRGKIVLEGEPENVLSDVS 227
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
 19-231 3.39e-29

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 117.88  E-value: 3.39e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  19 VLNDISLSLDPGEILFIIGASGCGKTT----LLRCLAGfeqpdSGEISLSGKTI--FSKNTNLPVReRRLGYLVQE--GV 90
Cdd:PRK15134  301 VVKNISFTLRPGETLGLVGESGSGKSTtglaLLRLINS-----QGEIWFDGQPLhnLNRRQLLPVR-HRIQVVFQDpnSS 374

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  91 LFPHLTVYRNIAYGLG-NGKGRTAQERQR--IEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFS 167
Cdd:PRK15134  375 LNPRLNVLQIIEEGLRvHQPTLSAAQREQqvIAVMEEVGLDPETRHRYPAEFSGGQRQRIAIARALILKPSLIILDEPTS 454

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1067578656 168 ALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPA 231
Cdd:PRK15134  455 SLDKTVQAQILALLKSLQQKHQLAYLFISHDLHVVRALCHQVIVLRQGEVVEQGDCERVFAAPQ 518
ABCC_cytochrome_bd cd03247
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ...
 5-217 5.93e-29

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.


Pssm-ID: 213214 [Multi-domain]  Cd Length: 178  Bit Score: 110.10  E-value: 5.93e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSF--QNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNTNLpvrERRL 82
Cdd:cd03247     1 LSINNVSFSYpeQEQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVPVSDLEKAL---SSLI 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  83 GYLVQEgvlfPHL---TVYRNIayglgngkgrtaqerqrieamleltgiselaGRyphELSGGQQQRVALARALAPDPEL 159
Cdd:cd03247    78 SVLNQR----PYLfdtTLRNNL-------------------------------GR---RFSGGERQRLALARILLQDAPI 119

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1067578656 160 ILLDEPFSALDEQLRRQIREDMIAALRanGKSAVFVSHdREEALQYADRIAVMKQGRI 217
Cdd:cd03247   120 VLLDEPTVGLDPITERQLLSLIFEVLK--DKTLIWITH-HLTGIEHMDKILFLENGKI 174
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
1-220 5.94e-29

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 116.55  E-value: 5.94e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   1 MTAALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNTNLPVrER 80
Cdd:PRK11288    1 SSPYLSFDGIGKTFPGVKALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQEMRFASTTAAL-AA 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  81 RLGYLVQEGVLFPHLTVYRNIAYG-LGNGKGRTAQERQRIEAMLELTGISE-LAGRYP-HELSGGQQQRVALARALAPDP 157
Cdd:PRK11288   80 GVAIIYQELHLVPEMTVAENLYLGqLPHKGGIVNRRLLNYEAREQLEHLGVdIDPDTPlKYLSIGQRQMVEIAKALARNA 159

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1067578656 158 ELILLDEPFSALD----EQLRRQIREdmiaaLRANGKSAVFVSHDREEALQYADRIAVMKQGRILQT 220
Cdd:PRK11288  160 RVIAFDEPTSSLSareiEQLFRVIRE-----LRAEGRVILYVSHRMEEIFALCDAITVFKDGRYVAT 221
PRK13633 PRK13633
energy-coupling factor transporter ATPase;
15-229 2.28e-28

energy-coupling factor transporter ATPase;


Pssm-ID: 237453 [Multi-domain]  Cd Length: 280  Bit Score: 111.33  E-value: 2.28e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  15 QNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNTNLPVRERrlgylvqEGVLFPH 94
Cdd:PRK13633   21 TEKLALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGLDTSDEENLWDIRNK-------AGMVFQN 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  95 -------LTVYRNIAYGLGNgKGRTAQE-RQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPF 166
Cdd:PRK13633   94 pdnqivaTIVEEDVAFGPEN-LGIPPEEiRERVDESLKKVGMYEYRRHAPHLLSGGQKQRVAIAGILAMRPECIIFDEPT 172

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1067578656 167 SALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQyADRIAVMKQGRILQTASPHELYRQ 229
Cdd:PRK13633  173 AMLDPSGRREVVNTIKELNKKYGITIILITHYMEEAVE-ADRIIVMDSGKVVMEGTPKEIFKE 234
BtuD COG4138
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ...
 20-225 2.36e-28

ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];


Pssm-ID: 443313 [Multi-domain]  Cd Length: 248  Bit Score: 110.70  E-value: 2.36e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  20 LNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFeQPDSGEISLSGKTIfsknTNLPVRE--RRLGYLVQEGVLFPHLTV 97
Cdd:COG4138    12 LGPISAQVNAGELIHLIGPNGAGKSTLLARMAGL-LPGQGEILLNGRPL----SDWSAAElaRHRAYLSQQQSPPFAMPV 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  98 YRNIAYGLGnGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALA-------PDPELILLDEPFSALD 170
Cdd:COG4138    87 FQYLALHQP-AGASSEAVEQLLAQLAEALGLEDKLSRPLTQLSGGEWQRVRLAAVLLqvwptinPEGQLLLLDEPMNSLD 165

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1067578656 171 eqLRRQIRED-MIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHE 225
Cdd:COG4138   166 --VAQQAALDrLLRELCQQGITVVMSSHDLNHTLRHADRVWLLKQGKLVASGETAE 219
PRK14246 PRK14246
phosphate ABC transporter ATP-binding protein; Provisional
 5-232 2.61e-28

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172734 [Multi-domain]  Cd Length: 257  Bit Score: 110.91  E-value: 2.61e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTI-FSKNT----NLPVRe 79
Cdd:PRK14246   11 FNISRLYLYINDKAILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEIYDSKIKVDGKVLyFGKDIfqidAIKLR- 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  80 RRLGYLVQEGVLFPHLTVYRNIAYGLGNGKGRTAQERQRI-EAMLELTGI-SELAGRY---PHELSGGQQQRVALARALA 154
Cdd:PRK14246   90 KEVGMVFQQPNPFPHLSIYDNIAYPLKSHGIKEKREIKKIvEECLRKVGLwKEVYDRLnspASQLSGGQQQRLTIARALA 169

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1067578656 155 PDPELILLDEPFSALDeQLRRQIREDMIAALRaNGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPAD 232
Cdd:PRK14246  170 LKPKVLLMDEPTSMID-IVNSQAIEKLITELK-NEIAIVIVSHNPQQVARVADYVAFLYNGELVEWGSSNEIFTSPKN 245
cbiO PRK13648
cobalt transporter ATP-binding subunit; Provisional
 20-250 3.21e-28

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184207 [Multi-domain]  Cd Length: 269  Bit Score: 110.61  E-value: 3.21e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  20 LNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsKNTNLPVRERRLGYLVQE-GVLFPHLTVY 98
Cdd:PRK13648   25 LKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAI--TDDNFEKLRKHIGIVFQNpDNQFVGSIVK 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  99 RNIAYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDEQLRRQIR 178
Cdd:PRK13648  103 YDVAFGLENHAVPYDEMHRRVSEALKQVDMLERADYEPNALSGGQKQRVAIAGVLALNPSVIILDEATSMLDPDARQNLL 182

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1067578656 179 eDMIAALRANGKSAVF-VSHDREEALQyADRIAVMKQGRILQTASPHELYRqpaDLDAALFIGEGIVFPAALN 250
Cdd:PRK13648  183 -DLVRKVKSEHNITIIsITHDLSEAME-ADHVIVMNKGTVYKEGTPTEIFD---HAEELTRIGLDLPFPIKIN 250
YddA COG4178
ABC-type uncharacterized transport system, permease and ATPase components [General function ...
 15-209 5.25e-28

ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];


Pssm-ID: 443337 [Multi-domain]  Cd Length: 571  Bit Score: 114.52  E-value: 5.25e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  15 QNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISL--SGKTIFskntnLPVRerrlGYLvqegvlf 92
Cdd:COG4178   374 DGRPLLEDLSLSLKPGERLLITGPSGSGKSTLLRAIAGLWPYGSGRIARpaGARVLF-----LPQR----PYL------- 437

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  93 PHLTVYRNIAYGlgngKGRTAQERQRIEAMLELTGISELAGRY------PHELSGGQQQRVALARALAPDPELILLDEPF 166
Cdd:COG4178   438 PLGTLREALLYP----ATAEAFSDAELREALEAVGLGHLAERLdeeadwDQVLSLGEQQRLAFARLLLHKPDWLFLDEAT 513

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1067578656 167 SALDEQLRRQiredMIAALRANGKSAVFVS--HdREEALQYADRI 209
Cdd:COG4178   514 SALDEENEAA----LYQLLREELPGTTVISvgH-RSTLAAFHDRV 553
CydC TIGR02868
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ...
 15-198 6.01e-28

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.


Pssm-ID: 274331 [Multi-domain]  Cd Length: 530  Bit Score: 113.99  E-value: 6.01e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  15 QNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNTNLPvrERRLGYLVQEGVLFpH 94
Cdd:TIGR02868 346 GAPPVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGVPVSSLDQDEV--RRRVSVCAQDAHLF-D 422

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  95 LTVYRNIAYGLGNGKGrtaqerQRIEAMLELTGISELAGRYPH-----------ELSGGQQQRVALARALAPDPELILLD 163
Cdd:TIGR02868 423 TTVRENLRLARPDATD------EELWAALERVGLADWLRALPDgldtvlgeggaRLSGGERQRLALARALLADAPILLLD 496

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1067578656 164 EPFSALDEQLRRQIREDMIAALRanGKSAVFVSHD 198
Cdd:TIGR02868 497 EPTEHLDAETADELLEDLLAALS--GRTVVLITHH 529
ABCC_TAP cd03248
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ...
 16-217 1.15e-27

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.


Pssm-ID: 213215 [Multi-domain]  Cd Length: 226  Bit Score: 108.33  E-value: 1.15e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  16 NTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFS-KNTNLpvrERRLGYLVQEGVLFPH 94
Cdd:cd03248    26 DTLVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPISQyEHKYL---HSKVSLVGQEPVLFAR 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  95 lTVYRNIAYGLGNGK-GRTAQERQRIEA----MLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSAL 169
Cdd:cd03248   103 -SLQDNIAYGLQSCSfECVKEAAQKAHAhsfiSELASGYDTEVGEKGSQLSGGQKQRVAIARALIRNPQVLILDEATSAL 181

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1067578656 170 DEQLRRQIREdmiAALRANGKSAVFVSHDREEALQYADRIAVMKQGRI 217
Cdd:cd03248   182 DAESEQQVQQ---ALYDWPERRTVLVIAHRLSTVERADQILVLDGGRI 226
3a01208 TIGR00958
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
 16-230 1.23e-27

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273363 [Multi-domain]  Cd Length: 711  Bit Score: 114.05  E-value: 1.23e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  16 NTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKtifskntnlPVRE-------RRLGYLVQE 88
Cdd:TIGR00958 493 DVPVLKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDGV---------PLVQydhhylhRQVALVGQE 563

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  89 GVLFPHlTVYRNIAYGLgngkgrTAQERQRIEAMLELTG----ISELAGRYPHE-------LSGGQQQRVALARALAPDP 157
Cdd:TIGR00958 564 PVLFSG-SVRENIAYGL------TDTPDEEIMAAAKAANahdfIMEFPNGYDTEvgekgsqLSGGQKQRIAIARALVRKP 636

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1067578656 158 ELILLDEPFSALDEQLRRQIREDMIAAlranGKSAVFVSHdREEALQYADRIAVMKQGRILQTASPHELYRQP 230
Cdd:TIGR00958 637 RVLILDEATSALDAECEQLLQESRSRA----SRTVLLIAH-RLSTVERADQILVLKKGSVVEMGTHKQLMEDQ 704
ABCF_EF-3 cd03221
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ...
 5-216 1.87e-27

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.


Pssm-ID: 213188 [Multi-domain]  Cd Length: 144  Bit Score: 105.22  E-value: 1.87e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTifskntnlpvrerRLGY 84
Cdd:cd03221     1 IELENLSKTYGGKLLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIVTWGSTV-------------KIGY 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  85 LVQegvlfphltvyrniayglgngkgrtaqerqrieamleltgiselagrypheLSGGQQQRVALARALAPDPELILLDE 164
Cdd:cd03221    68 FEQ---------------------------------------------------LSGGEKMRLALAKLLLENPNLLLLDE 96

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1067578656 165 PFSALDEQLRRQIREdmiaALRANGKSAVFVSHDREEALQYADRIAVMKQGR 216
Cdd:cd03221    97 PTNHLDLESIEALEE----ALKEYPGTVILVSHDRYFLDQVATKIIELEDGK 144
PRK14258 PRK14258
phosphate ABC transporter ATP-binding protein; Provisional
 1-232 2.45e-27

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184593 [Multi-domain]  Cd Length: 261  Bit Score: 108.20  E-value: 2.45e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   1 MTAALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDS-----GEISLSGKTIFSKNTNL 75
Cdd:PRK14258    4 LIPAIKVNNLSFYYDTQKILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMNELESevrveGRVEFFNQNIYERRVNL 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  76 PVRERRLGYLVQEGVLFPhLTVYRNIAYGLGNGKGRTAQERQRI-EAMLELTGISELAGRYPH----ELSGGQQQRVALA 150
Cdd:PRK14258   84 NRLRRQVSMVHPKPNLFP-MSVYDNVAYGVKIVGWRPKLEIDDIvESALKDADLWDEIKHKIHksalDLSGGQQQRLCIA 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 151 RALAPDPELILLDEPFSALDEQLRRQIrEDMIAALRANGK-SAVFVSHDREEALQYADRIAVMKQ-----GRILQTASPH 224
Cdd:PRK14258  163 RALAVKPKVLLMDEPCFGLDPIASMKV-ESLIQSLRLRSElTMVIVSHNLHQVSRLSDFTAFFKGnenriGQLVEFGLTK 241


                  ....*...
gi 1067578656 225 ELYRQPAD 232
Cdd:PRK14258  242 KIFNSPHD 249
PRK14247 PRK14247
phosphate ABC transporter ATP-binding protein; Provisional
 3-230 2.51e-27

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172735 [Multi-domain]  Cd Length: 250  Bit Score: 108.08  E-value: 2.51e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   3 AALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGF-----EQPDSGEISLSGKTIFskntNLPV 77
Cdd:PRK14247    2 NKIEIRDLKVSFGQVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLielypEARVSGEVYLDGQDIF----KMDV 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  78 RE--RRLGYLVQEGVLFPHLTVYRNIAYGLG-NGKGRTAQE-RQRIEAMLELTGI-SELAGRY---PHELSGGQQQRVAL 149
Cdd:PRK14247   78 IElrRRVQMVFQIPNPIPNLSIFENVALGLKlNRLVKSKKElQERVRWALEKAQLwDEVKDRLdapAGKLSGGQQQRLCI 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 150 ARALAPDPELILLDEPFSALD-------EQLRRQIREDMiaalrangkSAVFVSHDREEALQYADRIAVMKQGRILQTAS 222
Cdd:PRK14247  158 ARALAFQPEVLLADEPTANLDpentakiESLFLELKKDM---------TIVLVTHFPQQAARISDYVAFLYKGQIVEWGP 228


                  ....*...
gi 1067578656 223 PHELYRQP 230
Cdd:PRK14247  229 TREVFTNP 236
PRK13538 PRK13538
cytochrome c biogenesis heme-transporting ATPase CcmA;
22-197 3.34e-27

cytochrome c biogenesis heme-transporting ATPase CcmA;


Pssm-ID: 184125 [Multi-domain]  Cd Length: 204  Bit Score: 106.04  E-value: 3.34e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  22 DISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSkntnlpVRE---RRLGYLVQEGVLFPHLTVY 98
Cdd:PRK13538   19 GLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEPIRR------QRDeyhQDLLYLGHQPGIKTELTAL 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  99 RNIAYglgNGKGRTAQERQRIEAMLELTGiseLAGR--YP-HELSGGQQQRVALARALAPDPELILLDEPFSALDEQLRR 175
Cdd:PRK13538   93 ENLRF---YQRLHGPGDDEALWEALAQVG---LAGFedVPvRQLSAGQQRRVALARLWLTRAPLWILDEPFTAIDKQGVA 166

                         170       180
                  ....*....|....*....|..
gi 1067578656 176 QIrEDMIAALRANGKSAVFVSH 197
Cdd:PRK13538  167 RL-EALLAQHAEQGGMVILTTH 187
PRK14271 PRK14271
phosphate ABC transporter ATP-binding protein; Provisional
 9-240 3.82e-27

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172759 [Multi-domain]  Cd Length: 276  Bit Score: 108.26  E-value: 3.82e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   9 HLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCL-------AGFEQpdSGEISLSGKTIFSKNTNLPVReRR 81
Cdd:PRK14271   26 NLTLGFAGKTVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTLnrmndkvSGYRY--SGDVLLGGRSIFNYRDVLEFR-RR 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  82 LGYLVQEGVLFPhLTVYRNIAYGLGNGKGRTAQE-RQRIEAMLELTG----ISELAGRYPHELSGGQQQRVALARALAPD 156
Cdd:PRK14271  103 VGMLFQRPNPFP-MSIMDNVLAGVRAHKLVPRKEfRGVAQARLTEVGlwdaVKDRLSDSPFRLSGGQQQLLCLARTLAVN 181

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 157 PELILLDEPFSALDEQLRRQIrEDMIAALrANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPADLDAA 236
Cdd:PRK14271  182 PEVLLLDEPTSALDPTTTEKI-EEFIRSL-ADRLTVIIVTHNLAQAARISDRAALFFDGRLVEEGPTEQLFSSPKHAETA 259


                  ....
gi 1067578656 237 LFIG 240
Cdd:PRK14271  260 RYVA 263
livF PRK11614
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
1-218 6.67e-27

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;


Pssm-ID: 183231 [Multi-domain]  Cd Length: 237  Bit Score: 106.50  E-value: 6.67e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   1 MTAALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNTNLPVRER 80
Cdd:PRK11614    2 EKVMLSFDKVSAHYGKIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDITDWQTAKIMREA 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  81 RLgyLVQEG-VLFPHLTVYRNIAYGlGNGKGRTaQERQRIEAMLEL-TGISELAGRYPHELSGGQQQRVALARALAPDPE 158
Cdd:PRK11614   82 VA--IVPEGrRVFSRMTVEENLAMG-GFFAERD-QFQERIKWVYELfPRLHERRIQRAGTMSGGEQQMLAIGRALMSQPR 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 159 LILLDEPFSALDEQLRRQIReDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRIL 218
Cdd:PRK11614  158 LLLLDEPSLGLAPIIIQQIF-DTIEQLREQGMTIFLVEQNANQALKLADRGYVLENGHVV 216
PRK10584 PRK10584
putative ABC transporter ATP-binding protein YbbA; Provisional
 5-202 7.14e-27

putative ABC transporter ATP-binding protein YbbA; Provisional


Pssm-ID: 182569 [Multi-domain]  Cd Length: 228  Bit Score: 106.02  E-value: 7.14e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSF----QNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNTN--LPVR 78
Cdd:PRK10584    7 VEVHHLKKSVgqgeHELSILTGVELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLHQMDEEarAKLR 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  79 ERRLGYLVQEGVLFPHLTVYRNIAY-GLGNGKgRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDP 157
Cdd:PRK10584   87 AKHVGFVFQSFMLIPTLNALENVELpALLRGE-SSRQSRNGAKALLEQLGLGKRLDHLPAQLSGGEQQRVALARAFNGRP 165

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1067578656 158 ELILLDEPFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEA 202
Cdd:PRK10584  166 DVLFADEPTGNLDRQTGDKIADLLFSLNREHGTTLILVTHDLQLA 210
cbiO PRK13642
energy-coupling factor transporter ATPase;
20-252 7.29e-27

energy-coupling factor transporter ATPase;


Pssm-ID: 184202 [Multi-domain]  Cd Length: 277  Bit Score: 107.49  E-value: 7.29e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  20 LNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNT-NLpvrERRLGYLVQE-GVLFPHLTV 97
Cdd:PRK13642   23 LNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGELLTAENVwNL---RRKIGMVFQNpDNQFVGATV 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  98 YRNIAYGLGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDEQLRRQI 177
Cdd:PRK13642  100 EDDVAFGMENQGIPREEMIKRVDEALLAVNMLDFKTREPARLSGGQKQRVAVAGIIALRPEIIILDESTSMLDPTGRQEI 179

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1067578656 178 REDMIAALRANGKSAVFVSHDREEALQyADRIAVMKQGRILQTASPHELYRQPADLdaaLFIGEGIVFPAALNAD 252
Cdd:PRK13642  180 MRVIHEIKEKYQLTVLSITHDLDEAAS-SDRILVMKAGEIIKEAAPSELFATSEDM---VEIGLDVPFSSNLMKD 250
phnK PRK11701
phosphonate C-P lyase system protein PhnK; Provisional
 1-229 7.91e-27

phosphonate C-P lyase system protein PhnK; Provisional


Pssm-ID: 183280 [Multi-domain]  Cd Length: 258  Bit Score: 106.55  E-value: 7.91e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   1 MTAALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNTN-LPVRE 79
Cdd:PRK11701    3 DQPLLSVRGLTKLYGPRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYRMRDGQLRDLYaLSEAE 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  80 RRL------GYLVQ---EGvLFPHLTVYRNIAYGL--------GNGKGRTAQERQRIEamLELTGISELagryPHELSGG 142
Cdd:PRK11701   83 RRRllrtewGFVHQhprDG-LRMQVSAGGNIGERLmavgarhyGDIRATAGDWLERVE--IDAARIDDL----PTTFSGG 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 143 QQQRVALARALAPDPELILLDEPFSALDEQLrrQIR-EDMIAALRAN-GKSAVFVSHDREEALQYADRIAVMKQGRILQT 220
Cdd:PRK11701  156 MQQRLQIARNLVTHPRLVFMDEPTGGLDVSV--QARlLDLLRGLVRElGLAVVIVTHDLAVARLLAHRLLVMKQGRVVES 233

                         250
                  ....*....|....*.
gi 1067578656 221 A-------SPHELYRQ 229
Cdd:PRK11701  234 GltdqvldDPQHPYTQ 249
CP_lyasePhnK TIGR02323
phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P ...
 5-229 1.08e-26

phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated complex. This protein (PhnK) and the adjacent-encoded PhnL resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this complex rather than part of a transporter per se. [Central intermediary metabolism, Phosphorus compounds]


Pssm-ID: 188208 [Multi-domain]  Cd Length: 253  Bit Score: 106.07  E-value: 1.08e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKT-IFSKNTNLPVRERRLG 83
Cdd:TIGR02323   4 LQVSGLSKSYGGGKGCRDVSFDLYPGEVLGIVGESGSGKSTLLGCLAGRLAPDHGTATYIMRSgAELELYQLSEAERRRL 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  84 YLVQEGVLFPH------LTVY-------RNIAYGLGN-GKGRTAQERQRIEAMLELTGISELagryPHELSGGQQQRVAL 149
Cdd:TIGR02323  84 MRTEWGFVHQNprdglrMRVSaganigeRLMAIGARHyGNIRATAQDWLEEVEIDPTRIDDL----PRAFSGGMQQRLQI 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 150 ARALAPDPELILLDEPFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTA-------S 222
Cdd:TIGR02323 160 ARNLVTRPRLVFMDEPTGGLDVSVQARLLDLLRGLVRDLGLAVIIVTHDLGVARLLAQRLLVMQQGRVVESGltdqvldD 239


                  ....*..
gi 1067578656 223 PHELYRQ 229
Cdd:TIGR02323 240 PQHPYTQ 246
PRK11160 PRK11160
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 15-226 1.21e-26

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236865 [Multi-domain]  Cd Length: 574  Bit Score: 110.68  E-value: 1.21e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  15 QNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTI--FSKnTNLpvreRRLGYLVQEGV-L 91
Cdd:PRK11160  351 QPQPVLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILLNGQPIadYSE-AAL----RQAISVVSQRVhL 425

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  92 FPHlTVYRNIAYGLGNgkgrtAQERQRIEaMLELTGISELA-------------GRyphELSGGQQQRVALARALAPDPE 158
Cdd:PRK11160  426 FSA-TLRDNLLLAAPN-----ASDEALIE-VLQQVGLEKLLeddkglnawlgegGR---QLSGGEQRRLGIARALLHDAP 495

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 159 LILLDEPFSALDEQLRRQIredmIAALR--ANGKSAVFVSHdREEALQYADRIAVMKQGRILQTASPHEL 226
Cdd:PRK11160  496 LLLLDEPTEGLDAETERQI----LELLAehAQNKTVLMITH-RLTGLEQFDRICVMDNGQIIEQGTHQEL 560
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
 2-231 1.31e-26

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 110.18  E-value: 1.31e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   2 TAALHIGHLSKSFQNT----PVLNDISLSLDPGEILFIIGASGCGKT-TLLRCLAGFEQPD----SGEISLSGKTIF--S 70
Cdd:PRK15134    3 QPLLAIENLSVAFRQQqtvrTVVNDVSLQIEAGETLALVGESGSGKSvTALSILRLLPSPPvvypSGDIRFHGESLLhaS 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  71 KNTNLPVRERRLGYLVQEGV--LFPHLTVYRNIAYGLGNGKG-RTAQERQRIEAMLELTGISELAGR---YPHELSGGQQ 144
Cdd:PRK15134   83 EQTLRGVRGNKIAMIFQEPMvsLNPLHTLEKQLYEVLSLHRGmRREAARGEILNCLDRVGIRQAAKRltdYPHQLSGGER 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 145 QRVALARALAPDPELILLDEPFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPH 224
Cdd:PRK15134  163 QRVMIAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQQELNMGLLFITHNLSIVRKLADRVAVMQNGRCVEQNRAA 242


                  ....*..
gi 1067578656 225 ELYRQPA 231
Cdd:PRK15134  243 TLFSAPT 249
ABCG_White cd03234
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...
 19-218 1.55e-26

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.


Pssm-ID: 213201 [Multi-domain]  Cd Length: 226  Bit Score: 105.05  E-value: 1.55e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  19 VLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPD---SGEISLSGKTIfSKNTNLpvreRRLGYLVQEGVLFPHL 95
Cdd:cd03234    22 ILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRVEGGgttSGQILFNGQPR-KPDQFQ----KCVAYVRQDDILLPGL 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  96 TVYRNIAYGLGNGKGRTAQERQRiEAMLELTGISELA-----GRYPHELSGGQQQRVALARALAPDPELILLDEPFSALD 170
Cdd:cd03234    97 TVRETLTYTAILRLPRKSSDAIR-KKRVEDVLLRDLAltrigGNLVKGISGGERRRVSIAVQLLWDPKVLILDEPTSGLD 175

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1067578656 171 EQLRRQIredmIAALR--ANGKSAVFVS-HD-REEALQYADRIAVMKQGRIL 218
Cdd:cd03234   176 SFTALNL----VSTLSqlARRNRIVILTiHQpRSDLFRLFDRILLLSSGEIV 223
ABC_NatA_like cd03267
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...
 14-218 3.41e-26

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.


Pssm-ID: 213234 [Multi-domain]  Cd Length: 236  Bit Score: 104.34  E-value: 3.41e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  14 FQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGktifskntNLPVrERRLGYLVQEGVLF- 92
Cdd:cd03267    31 YREVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVAG--------LVPW-KRRKKFLRRIGVVFg 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  93 ---------PHLTVYRNIA--YGLgnGKGRTAQERQRIEAMLELTGISELAGRyphELSGGQQQRVALARALAPDPELIL 161
Cdd:cd03267   102 qktqlwwdlPVIDSFYLLAaiYDL--PPARFKKRLDELSELLDLEELLDTPVR---QLSLGQRMRAEIAAALLHEPEILF 176

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1067578656 162 LDEPFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRIL 218
Cdd:cd03267   177 LDEPTIGLDVVAQENIRNFLKEYNRERGTTVLLTSHYMKDIEALARRVLVIDKGRLL 233
PRK11174 PRK11174
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 13-230 5.55e-26

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236870 [Multi-domain]  Cd Length: 588  Bit Score: 108.78  E-value: 5.55e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  13 SFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFeQPDSGEISLSGktIFSKNTNLPVRERRLGYLVQEGVLF 92
Cdd:PRK11174  359 SPDGKTLAGPLNFTLPAGQRIALVGPSGAGKTSLLNALLGF-LPYQGSLKING--IELRELDPESWRKHLSWVGQNPQLP 435

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  93 pHLTVYRNIAygLGNGkgrTAQErQRIEAMLELTGISELAGRYPH-----------ELSGGQQQRVALARALAPDPELIL 161
Cdd:PRK11174  436 -HGTLRDNVL--LGNP---DASD-EQLQQALENAWVSEFLPLLPQgldtpigdqaaGLSVGQAQRLALARALLQPCQLLL 508

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1067578656 162 LDEPFSALDEQLRRQIREDMIAAlrANGKSAVFVSHdREEALQYADRIAVMKQGRILQTASPHELYRQP 230
Cdd:PRK11174  509 LDEPTASLDAHSEQLVMQALNAA--SRRQTTLMVTH-QLEDLAQWDQIWVMQDGQIVQQGDYAELSQAG 574
PRK14243 PRK14243
phosphate transporter ATP-binding protein; Provisional
 10-210 6.70e-26

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184588 [Multi-domain]  Cd Length: 264  Bit Score: 104.48  E-value: 6.70e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  10 LSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRC-------LAGFEQpdSGEISLSGKTIFSKNTNlPVR-ERR 81
Cdd:PRK14243   16 LNVYYGSFLAVKNVWLDIPKNQITAFIGPSGCGKSTILRCfnrlndlIPGFRV--EGKVTFHGKNLYAPDVD-PVEvRRR 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  82 LGYLVQEGVLFPHlTVYRNIAYGLG-NG-KG----------RTAQERQRIEAMLELTGISelagrypheLSGGQQQRVAL 149
Cdd:PRK14243   93 IGMVFQKPNPFPK-SIYDNIAYGARiNGyKGdmdelverslRQAALWDEVKDKLKQSGLS---------LSGGQQQRLCI 162

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1067578656 150 ARALAPDPELILLDEPFSALDEQLRRQIrEDMIAALRANgKSAVFVSHDREEALQYADRIA 210
Cdd:PRK14243  163 ARAIAVQPEVILMDEPCSALDPISTLRI-EELMHELKEQ-YTIIIVTHNMQQAARVSDMTA 221
FbpC_C_terminal pfam17845
FbpC C-terminal regulatory nucleotide binding domain; Most functional ABC transporters are ...
 295-349 1.19e-25

FbpC C-terminal regulatory nucleotide binding domain; Most functional ABC transporters are composed of at least four sub-units: two trans-membrane (TM) domains where the transport process takes place and two cytoplasmic nucleotide binding domains (NBDs) providing the energy required for active transport. This entry is one of the two NBDs found at the the C-terminal domain of FbpC, ferric iron uptake transporter, from the Neisseria gonorrhoeae. The C-terminal regulatory domain adopts two OB-folds per monomer. These are similar in topology to those seen in the NBD (nucleotide binding domain) from the maltose uptake ABC transporter, MalK. However, FbpC does not open as far as MalK when ATP is removed from their respective closed structures. This difference was suggested to be due to the substantial domain swap in the regulatory domain of FbpC.


Pssm-ID: 407710  Cd Length: 55  Bit Score: 97.36  E-value: 1.19e-25
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1067578656 295 IHAVVLKTTPKARHTEISLRAGQTVLTLNLPSAPTLSDGISAVLHLDGPALFFPG 349
Cdd:pfam17845   1 IHAVVLKTTPKARHTEISLRGGQTVLTLNLPSAPTLSDGISAVLHLDGPALFFPG 55
cbiO PRK13638
energy-coupling factor ABC transporter ATP-binding protein;
14-236 2.28e-25

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184198 [Multi-domain]  Cd Length: 271  Bit Score: 103.16  E-value: 2.28e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  14 FQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTI-FSKNTNLPVRERRLGYLVQEGVLF 92
Cdd:PRK13638   11 YQDEPVLKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQGKPLdYSKRGLLALRQQVATVFQDPEQQI 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  93 PHLTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGiselAGRYPHE----LSGGQQQRVALARALAPDPELILLDEPFSA 168
Cdd:PRK13638   91 FYTDIDSDIAFSLRNLGVPEAEITRRVDEALTLVD----AQHFRHQpiqcLSHGQKKRVAIAGALVLQARYLLLDEPTAG 166

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1067578656 169 LDEQLRRQiredMIAALR---ANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPADLDAA 236
Cdd:PRK13638  167 LDPAGRTQ----MIAIIRrivAQGNHVIISSHDIDLIYEISDAVYVLRQGQILTHGAPGEVFACTEAMEQA 233
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
 1-220 2.44e-25

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 106.55  E-value: 2.44e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   1 MTAALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFeQPD---SGEISLSGKTIFSKNtnlpV 77
Cdd:PRK13549    2 MEYLLEMKNITKTFGGVKALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSGV-YPHgtyEGEIIFEGEELQASN----I 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  78 RE-RRLGYLV--QEGVLFPHLTVYRNIAygLGN---GKGRTAQER--QRIEAMLELTGISELAGRYPHELSGGQQQRVAL 149
Cdd:PRK13549   77 RDtERAGIAIihQELALVKELSVLENIF--LGNeitPGGIMDYDAmyLRAQKLLAQLKLDINPATPVGNLGLGQQQLVEI 154

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1067578656 150 ARALAPDPELILLDEPFSALDEQlRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQT 220
Cdd:PRK13549  155 AKALNKQARLLILDEPTASLTES-ETAVLLDIIRDLKAHGIACIYISHKLNEVKAISDTICVIRDGRHIGT 224
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
1-215 5.25e-25

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 105.64  E-value: 5.25e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   1 MTAALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTiFSKNTNLPVRER 80
Cdd:PRK09700    2 ATPYISMAGIGKSFGPVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNIN-YNKLDHKLAAQL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  81 RLGYLVQEGVLFPHLTVYRNIAYG-------LGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARAL 153
Cdd:PRK09700   81 GIGIIYQELSVIDELTVLENLYIGrhltkkvCGVNIIDWREMRVRAAMMLLRVGLKVDLDEKVANLSISHKQMLEIAKTL 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1067578656 154 APDPELILLDEPFSALD----EQLRRQIREdmiaaLRANGKSAVFVSHDREEALQYADRIAVMKQG 215
Cdd:PRK09700  161 MLDAKVIIMDEPTSSLTnkevDYLFLIMNQ-----LRKEGTAIVYISHKLAEIRRICDRYTVMKDG 221
PRK15112 PRK15112
peptide ABC transporter ATP-binding protein SapF;
5-252 5.59e-25

peptide ABC transporter ATP-binding protein SapF;


Pssm-ID: 185067 [Multi-domain]  Cd Length: 267  Bit Score: 101.79  E-value: 5.59e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSF---------QNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsKNTNL 75
Cdd:PRK15112    5 LEVRNLSKTFryrtgwfrrQTVEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPL--HFGDY 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  76 PVRERRLGYLVQE--GVLFPHLTVYRNIAYGLGNGKGRTAQER-QRIEAMLELTGI-SELAGRYPHELSGGQQQRVALAR 151
Cdd:PRK15112   83 SYRSQRIRMIFQDpsTSLNPRQRISQILDFPLRLNTDLEPEQReKQIIETLRQVGLlPDHASYYPHMLAPGQKQRLGLAR 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 152 ALAPDPELILLDEPFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPA 231
Cdd:PRK15112  163 ALILRPKVIIADEALASLDMSMRSQLINLMLELQEKQGISYIYVTQHLGMMKHISDQVLVMHQGEVVERGSTADVLASPL 242

                         250       260
                  ....*....|....*....|..
gi 1067578656 232 -DLDAALFIGEgivFPAALNAD 252
Cdd:PRK15112  243 hELTKRLIAGH---FGEALTAD 261
ATM1 COG5265
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ...
 18-229 1.11e-24

ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444078 [Multi-domain]  Cd Length: 605  Bit Score: 104.90  E-value: 1.11e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  18 PVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfSKNTNLPVReRRLGYLVQEGVLFpHLTV 97
Cdd:COG5265   372 PILKGVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRILIDGQDI-RDVTQASLR-AAIGIVPQDTVLF-NDTI 448

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  98 YRNIAYGlgngkgRTAQERQRIEAMLELTGISELAGRYPH-----------ELSGGQQQRVALARALAPDPELILLDEPF 166
Cdd:COG5265   449 AYNIAYG------RPDASEEEVEAAARAAQIHDFIESLPDgydtrvgerglKLSGGEKQRVAIARTLLKNPPILIFDEAT 522

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1067578656 167 SALDEQLRRQIRedmiAALR--ANGKSAVFVSHdREEALQYADRIAVMKQGRILQTASPHELYRQ 229
Cdd:COG5265   523 SALDSRTERAIQ----AALRevARGRTTLVIAH-RLSTIVDADEILVLEAGRIVERGTHAELLAQ 582
PRK10253 PRK10253
iron-enterobactin ABC transporter ATP-binding protein;
2-226 1.60e-24

iron-enterobactin ABC transporter ATP-binding protein;


Pssm-ID: 182336 [Multi-domain]  Cd Length: 265  Bit Score: 100.83  E-value: 1.60e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   2 TAALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTI---FSKNTnlpvr 78
Cdd:PRK10253    5 VARLRGEQLTLGYGKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIqhyASKEV----- 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  79 ERRLGYLVQEGVLFPHLTVYRNIAYGLGNGKGRTAQERQRIE----AMLELTGISELAGRYPHELSGGQQQRVALARALA 154
Cdd:PRK10253   80 ARRIGLLAQNATTPGDITVQELVARGRYPHQPLFTRWRKEDEeavtKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLA 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1067578656 155 PDPELILLDEPFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHEL 226
Cdd:PRK10253  160 QETAIMLLDEPTTWLDISHQIDLLELLSELNREKGYTLAAVLHDLNQACRYASHLIALREGKIVAQGAPKEI 231
SufC COG0396
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ...
 5-226 1.89e-24

Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440165 [Multi-domain]  Cd Length: 245  Bit Score: 99.76  E-value: 1.89e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFE--QPDSGEISLSGKTIfsknTNLPVRER-R 81
Cdd:COG0396     1 LEIKNLHVSVEGKEILKGVNLTIKPGEVHAIMGPNGSGKSTLAKVLMGHPkyEVTSGSILLDGEDI----LELSPDERaR 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  82 LG--YLVQEGVLFPHLTVYR--NIAYGLGNGKGRTAQE-RQRIEAMLELTGISE-LAGRYPHE-LSGGQQQRVALARALA 154
Cdd:COG0396    77 AGifLAFQYPVEIPGVSVSNflRTALNARRGEELSAREfLKLLKEKMKELGLDEdFLDRYVNEgFSGGEKKRNEILQMLL 156

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1067578656 155 PDPELILLDEPFSALD-EQLRrqIREDMIAALRANGKSAVFVSHdREEALQY--ADRIAVMKQGRILQTASPhEL 226
Cdd:COG0396   157 LEPKLAILDETDSGLDiDALR--IVAEGVNKLRSPDRGILIITH-YQRILDYikPDFVHVLVDGRIVKSGGK-EL 227
PRK15056 PRK15056
manganese/iron ABC transporter ATP-binding protein;
1-237 2.25e-24

manganese/iron ABC transporter ATP-binding protein;


Pssm-ID: 185016 [Multi-domain]  Cd Length: 272  Bit Score: 100.34  E-value: 2.25e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   1 MTAALHIGHLSKSFQNT-PVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISlsgktIFSKNTNLPVRE 79
Cdd:PRK15056    3 QQAGIVVNDVTVTWRNGhTALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKIS-----ILGQPTRQALQK 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  80 RRLGYLVQEGVL---FPHLT--VYRNIAYG-LGNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARAL 153
Cdd:PRK15056   78 NLVAYVPQSEEVdwsFPVLVedVVMMGRYGhMGWLRRAKKRDRQIVTAALARVDMVEFRHRQIGELSGGQKKRVFLARAI 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 154 APDPELILLDEPFSALDEQLRRQIReDMIAALRANGKSAVFVSHDREEALQYADrIAVMKQGRILqTASPHELYRQPADL 233
Cdd:PRK15056  158 AQQGQVILLDEPFTGVDVKTEARII-SLLRELRDEGKTMLVSTHNLGSVTEFCD-YTVMVKGTVL-ASGPTETTFTAENL 234


                  ....
gi 1067578656 234 DAAL 237
Cdd:PRK15056  235 ELAF 238
ccmA TIGR01189
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ...
 17-197 3.84e-24

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]


Pssm-ID: 273491 [Multi-domain]  Cd Length: 198  Bit Score: 97.81  E-value: 3.84e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  17 TPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfskNTNLPVRERRLGYLVQEGVLFPHLT 96
Cdd:TIGR01189  13 RMLFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPL---AEQRDEPHENILYLGHLPGLKPELS 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  97 VYRNIAYGLGNGKGrtaqERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDEQLRRQ 176
Cdd:TIGR01189  90 ALENLHFWAAIHGG----AQRTIEDALAAVGLTGFEDLPAAQLSAGQQRRLALARLWLSRRPLWILDEPTTALDKAGVAL 165

                         170       180
                  ....*....|....*....|.
gi 1067578656 177 IREDMIAALrANGKSAVFVSH 197
Cdd:TIGR01189 166 LAGLLRAHL-ARGGIVLLTTH 185
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
 5-226 4.66e-24

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 102.96  E-value: 4.66e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQ--PDSGEI--------------------- 61
Cdd:TIGR03269   1 IEVKNLTKKFDGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMDQyePTSGRIiyhvalcekcgyverpskvge 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  62 --SLSGKTIFSKNTNL-----PVRE---RRLGYLVQEG-VLFPHLTVYRNIAYGLgNGKGRTAQERqrIEAMLELTGISE 130
Cdd:TIGR03269  81 pcPVCGGTLEPEEVDFwnlsdKLRRrirKRIAIMLQRTfALYGDDTVLDNVLEAL-EEIGYEGKEA--VGRAVDLIEMVQ 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 131 LAGRYPH---ELSGGQQQRVALARALAPDPELILLDEPFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYAD 207
Cdd:TIGR03269 158 LSHRITHiarDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKASGISMVLTSHWPEVIEDLSD 237

                         250
                  ....*....|....*....
gi 1067578656 208 RIAVMKQGRILQTASPHEL 226
Cdd:TIGR03269 238 KAIWLENGEIKEEGTPDEV 256
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
21-219 5.01e-24

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 102.56  E-value: 5.01e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  21 NDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfSKNTNLPVRERRLGYLVQ---EGVLFPHLTV 97
Cdd:PRK09700  280 RDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDI-SPRSPLDAVKKGMAYITEsrrDNGFFPNFSI 358

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  98 YRNIA-------------YGLGNGK--GRTAQErQRIEAMLELTGISELAGryphELSGGQQQRVALARALAPDPELILL 162
Cdd:PRK09700  359 AQNMAisrslkdggykgaMGLFHEVdeQRTAEN-QRELLALKCHSVNQNIT----ELSGGNQQKVLISKWLCCCPEVIIF 433

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1067578656 163 DEPFSALDEQLRRQIREDMiAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQ 219
Cdd:PRK09700  434 DEPTRGIDVGAKAEIYKVM-RQLADDGKVILMVSSELPEIITVCDRIAVFCEGRLTQ 489
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
 5-220 7.98e-24

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 102.21  E-value: 7.98e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDS--GEISLSGKTIFSKNtnlpVRE-RR 81
Cdd:TIGR02633   2 LEMKGIVKTFGGVKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGVYPHGTwdGEIYWSGSPLKASN----IRDtER 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  82 LGYLV--QEGVLFPHLTVYRNIAYG----LGNGKGRTAQERQRIEAMLELTGISEL-AGRYPHELSGGQQQRVALARALA 154
Cdd:TIGR02633  78 AGIVIihQELTLVPELSVAENIFLGneitLPGGRMAYNAMYLRAKNLLRELQLDADnVTRPVGDYGGGQQQLVEIAKALN 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1067578656 155 PDPELILLDEPFSALDEQlRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQT 220
Cdd:TIGR02633 158 KQARLLILDEPSSSLTEK-ETEILLDIIRDLKAHGVACVYISHKLNEVKAVCDTICVIRDGQHVAT 222
PRK10575 PRK10575
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
19-230 9.10e-24

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;


Pssm-ID: 182561 [Multi-domain]  Cd Length: 265  Bit Score: 98.71  E-value: 9.10e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  19 VLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNTNLPVRErrLGYLVQEGVLFPHLTVY 98
Cdd:PRK10575   26 LLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARK--VAYLPQQLPAAEGMTVR 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  99 RNIA---YGLGNGKGRTAQE-RQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDeqLR 174
Cdd:PRK10575  104 ELVAigrYPWHGALGRFGAAdREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALD--IA 181

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 175 RQIreDMIAAL----RANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQP 230
Cdd:PRK10575  182 HQV--DVLALVhrlsQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAELMRGE 239
PRK10789 PRK10789
SmdA family multidrug ABC transporter permease/ATP-binding protein;
15-230 9.18e-24

SmdA family multidrug ABC transporter permease/ATP-binding protein;


Pssm-ID: 182732 [Multi-domain]  Cd Length: 569  Bit Score: 102.10  E-value: 9.18e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  15 QNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsKNTNLPVRERRLGYLVQEGVLFPH 94
Cdd:PRK10789  326 TDHPALENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGDIRFHDIPL--TKLQLDSWRSRLAVVSQTPFLFSD 403

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  95 lTVYRNIAYGlgngkgRTAQERQRIEAMLELTGISELAGRYPH-----------ELSGGQQQRVALARALAPDPELILLD 163
Cdd:PRK10789  404 -TVANNIALG------RPDATQQEIEHVARLASVHDDILRLPQgydtevgergvMLSGGQKQRISIARALLLNAEILILD 476

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1067578656 164 EPFSALDEQLRRQIREDmiaaLRANGKS-AVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQP 230
Cdd:PRK10789  477 DALSAVDGRTEHQILHN----LRQWGEGrTVIISAHRLSALTEASEILVMQHGHIAQRGNHDQLAQQS 540
cbiO PRK13645
energy-coupling factor transporter ATPase;
20-227 1.34e-23

energy-coupling factor transporter ATPase;


Pssm-ID: 184204 [Multi-domain]  Cd Length: 289  Bit Score: 98.54  E-value: 1.34e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  20 LNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTI---FSKNTNLPVRERRLGYLVQ--EGVLFPH 94
Cdd:PRK13645   27 LNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTIVGDYAIpanLKKIKEVKRLRKEIGLVFQfpEYQLFQE 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  95 lTVYRNIAYGLGNGKGRTAQERQRIEAMLELTGI-SELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDEQL 173
Cdd:PRK13645  107 -TIEKDIAFGPVNLGENKQEAYKKVPELLKLVQLpEDYVKRSPFELSGGQKRRVALAGIIAMDGNTLVLDEPTGGLDPKG 185

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1067578656 174 rrqiREDMIAA-LRAN---GKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELY 227
Cdd:PRK13645  186 ----EEDFINLfERLNkeyKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGSPFEIF 239
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
4-239 1.90e-23

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 101.74  E-value: 1.90e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   4 ALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKntnlpvRER--- 80
Cdd:NF033858    1 VARLEGVSHRYGKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVLGGDMADA------RHRrav 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  81 --RLGYLVQeGV---LFPHLTVYRNIA-----YGLGngkgrtAQER-QRIEAMLELTGISELAGRYPHELSGGQQQRVAL 149
Cdd:NF033858   75 cpRIAYMPQ-GLgknLYPTLSVFENLDffgrlFGQD------AAERrRRIDELLRATGLAPFADRPAGKLSGGMKQKLGL 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 150 ARALAPDPELILLDEPFSALDEQLRRQIREdMIAALRAN--GKSAVFVSHDREEALQYaDRIAVMKQGRILQTASPHELY 227
Cdd:NF033858  148 CCALIHDPDLLILDEPTTGVDPLSRRQFWE-LIDRIRAErpGMSVLVATAYMEEAERF-DWLVAMDAGRVLATGTPAELL 225

                         250
                  ....*....|....
gi 1067578656 228 RQ--PADLDAAlFI 239
Cdd:NF033858  226 ARtgADTLEAA-FI 238
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 9-210 2.35e-23

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 100.78  E-value: 2.35e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   9 HLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLsGKTIfskntnlpvrerRLGYLVQE 88
Cdd:TIGR03719 327 NLTKAFGDKLLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEI-GETV------------KLAYVDQS 393

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  89 -GVLFPHLTVYRNIAYG-----LGNgkgRTAQERQRIEAmLELTGISE--LAGryphELSGGQQQRVALARALAPDPELI 160
Cdd:TIGR03719 394 rDALDPNKTVWEEISGGldiikLGK---REIPSRAYVGR-FNFKGSDQqkKVG----QLSGGERNRVHLAKTLKSGGNVL 465

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1067578656 161 LLDEPFSALD-EQLRRQirEDmiaALRANGKSAVFVSHDReealQYADRIA 210
Cdd:TIGR03719 466 LLDEPTNDLDvETLRAL--EE---ALLNFAGCAVVISHDR----WFLDRIA 507
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
 1-261 2.61e-23

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 100.46  E-value: 2.61e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   1 MTAALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfskNTNLP--VR 78
Cdd:PRK10762    1 MQALLQLKGIDKAFPGVKALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSILYLGKEV---TFNGPksSQ 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  79 ERRLGYLVQEGVLFPHLTVYRNIAYG--LGNGKGRTAQERQRIEA--MLELTGISELAGRYPHELSGGQQQRVALARALA 154
Cdd:PRK10762   78 EAGIGIIHQELNLIPQLTIAENIFLGreFVNRFGRIDWKKMYAEAdkLLARLNLRFSSDKLVGELSIGEQQMVEIAKVLS 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 155 PDPELILLDEPFSAL----DEQLRRQIREdmiaaLRANGKSAVFVSHDREEALQYADRIAVMKQGRilqtasphelyrqp 230
Cdd:PRK10762  158 FESKVIIMDEPTDALtdteTESLFRVIRE-----LKSQGRGIVYISHRLKEIFEICDDVTVFRDGQ-------------- 218

                         250       260       270
                  ....*....|....*....|....*....|.
gi 1067578656 231 adldaalFIGEGIVfpAALNADGTADCRLGR 261
Cdd:PRK10762  219 -------FIAEREV--ADLTEDSLIEMMVGR 240
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
9-240 2.94e-23

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 100.97  E-value: 2.94e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   9 HLSKSFQN-TPVlNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNtnLPVReRRLGYLVQ 87
Cdd:NF033858  271 GLTMRFGDfTAV-DHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQPVDAGD--IATR-RRVGYMSQ 346

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  88 EGVLFPHLTVYRNIA-----YGLGngkgrTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILL 162
Cdd:NF033858  347 AFSLYGELTVRQNLElharlFHLP-----AAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLIL 421

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 163 DEPFSALDEQLRRQIREDMIAALRaNGKSAVFVS-HDREEAlQYADRIAVMKQGRILQTASPHELY--RQPADLDAAlFI 239
Cdd:NF033858  422 DEPTSGVDPVARDMFWRLLIELSR-EDGVTIFIStHFMNEA-ERCDRISLMHAGRVLASDTPAALVaaRGAATLEEA-FI 498


                  .
gi 1067578656 240 G 240
Cdd:NF033858  499 A 499
PRK03695 PRK03695
vitamin B12-transporter ATPase; Provisional
 23-230 3.55e-23

vitamin B12-transporter ATPase; Provisional


Pssm-ID: 235150 [Multi-domain]  Cd Length: 248  Bit Score: 96.54  E-value: 3.55e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  23 ISLSLDPGEILFIIGASGCGKTTLLRCLAGFeQPDSGEISLSGKTIfsknTNLPVRE--RRLGYLVQEGVLFPHLTVYRN 100
Cdd:PRK03695   15 LSAEVRAGEILHLVGPNGAGKSTLLARMAGL-LPGSGSIQFAGQPL----EAWSAAElaRHRAYLSQQQTPPFAMPVFQY 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 101 IAYGLGNGkGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALA-------RALAPDPELILLDEPFSALD--E 171
Cdd:PRK03695   90 LTLHQPDK-TRTEAVASALNEVAEALGLDDKLGRSVNQLSGGEWQRVRLAavvlqvwPDINPAGQLLLLDEPMNSLDvaQ 168

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1067578656 172 Q--LRRQIREdmiaaLRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQP 230
Cdd:PRK03695  169 QaaLDRLLSE-----LCQQGIAVVMSSHDLNHTLRHADRVWLLKQGKLLASGRRDEVLTPE 224
PRK11176 PRK11176
lipid A ABC transporter ATP-binding protein/permease MsbA;
16-229 3.94e-23

lipid A ABC transporter ATP-binding protein/permease MsbA;


Pssm-ID: 183016 [Multi-domain]  Cd Length: 582  Bit Score: 100.48  E-value: 3.94e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  16 NTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfskntnlpvRERRLGYL------VQEG 89
Cdd:PRK11176  355 EVPALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILLDGHDL---------RDYTLASLrnqvalVSQN 425

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  90 VlfpHL---TVYRNIAYGlgngkgRTAQ-ERQRIEAMLELTGISELAGRYPH-----------ELSGGQQQRVALARALA 154
Cdd:PRK11176  426 V---HLfndTIANNIAYA------RTEQySREQIEEAARMAYAMDFINKMDNgldtvigengvLLSGGQRQRIAIARALL 496

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1067578656 155 PDPELILLDEPFSALDEQLRRQIREdMIAALRANgKSAVFVSHdREEALQYADRIAVMKQGRILQTASPHELYRQ 229
Cdd:PRK11176  497 RDSPILILDEATSALDTESERAIQA-ALDELQKN-RTSLVIAH-RLSTIEKADEILVVEDGEIVERGTHAELLAQ 568
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
 8-235 6.30e-23

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 99.35  E-value: 6.30e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   8 GHLSKSFQNTPVLN----------DISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPV 77
Cdd:PRK15439  257 GNRRQQAAGAPVLTvedltgegfrNISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKEI----NALST 332

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  78 RERRLGYLV------QEGVLFPHLTVYRNIAYGLGNGKG---RTAQERQRIEAMLELTGIselagRYPHE------LSGG 142
Cdd:PRK15439  333 AQRLARGLVylpedrQSSGLYLDAPLAWNVCALTHNRRGfwiKPARENAVLERYRRALNI-----KFNHAeqaartLSGG 407

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 143 QQQRVALARALAPDPELILLDEPFSALDEQLRRQIReDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRIlqtas 222
Cdd:PRK15439  408 NQQKVLIAKCLEASPQLLIVDEPTRGVDVSARNDIY-QLIRSIAAQNVAVLFISSDLEEIEQMADRVLVMHQGEI----- 481

                         250
                  ....*....|...
gi 1067578656 223 PHELYRQPADLDA 235
Cdd:PRK15439  482 SGALTGAAINVDT 494
ABC_FeS_Assembly cd03217
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ...
 5-229 6.89e-23

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.


Pssm-ID: 213184 [Multi-domain]  Cd Length: 200  Bit Score: 94.52  E-value: 6.89e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFE--QPDSGEISLSGKTIfsknTNLPVRER-R 81
Cdd:cd03217     1 LEIKDLHVSVGGKEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGHPkyEVTEGEILFKGEDI----TDLPPEERaR 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  82 LGYLV--QEGVLFPHLTV---YRNIAYGlgngkgrtaqerqrieamleltgiselagrypheLSGGQQQRVALARALAPD 156
Cdd:cd03217    77 LGIFLafQYPPEIPGVKNadfLRYVNEG----------------------------------FSGGEKKRNEILQLLLLE 122

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1067578656 157 PELILLDEPFSALD-EQLRrqIREDMIAALRANGKSAVFVSHdREEALQY--ADRIAVMKQGRILQTASPhELYRQ 229
Cdd:cd03217   123 PDLAILDEPDSGLDiDALR--LVAEVINKLREEGKSVLIITH-YQRLLDYikPDRVHVLYDGRIVKSGDK-ELALE 194
ABCC_CFTR1 cd03291
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ...
 6-237 7.19e-23

ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213258 [Multi-domain]  Cd Length: 282  Bit Score: 96.46  E-value: 7.19e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   6 HIGHLSKSFQN-----TPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKntnlpvrer 80
Cdd:cd03291    34 SSDDNNLFFSNlclvgAPVLKNINLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKIKHSGRISFSS--------- 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  81 rlgylvQEGVLFPHlTVYRNIAYGLgngkgrtAQERQRIEAMLELTGISELAGRYPHE-----------LSGGQQQRVAL 149
Cdd:cd03291   105 ------QFSWIMPG-TIKENIIFGV-------SYDEYRYKSVVKACQLEEDITKFPEKdntvlgeggitLSGGQRARISL 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 150 ARALAPDPELILLDEPFSALDEQLRRQIREDMIAALRANgKSAVFVShDREEALQYADRIAVMKQGRILQTASPHELYRQ 229
Cdd:cd03291   171 ARAVYKDADLYLLDSPFGYLDVFTEKEIFESCVCKLMAN-KTRILVT-SKMEHLKKADKILILHEGSSYFYGTFSELQSL 248


                  ....*...
gi 1067578656 230 PADLDAAL 237
Cdd:cd03291   249 RPDFSSKL 256
ABCC_SUR1_N cd03290
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ...
 16-215 1.42e-22

ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213257 [Multi-domain]  Cd Length: 218  Bit Score: 94.32  E-value: 1.42e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  16 NTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNTNLPVRERR--LGYLVQEGVLFp 93
Cdd:cd03290    13 GLATLSNINIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNKNESEPSFEATRSRNRysVAYAAQKPWLL- 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  94 HLTVYRNIAYGlgngkgrTAQERQRIEAMLELTGISELAGRYPH-----------ELSGGQQQRVALARALAPDPELILL 162
Cdd:cd03290    92 NATVEENITFG-------SPFNKQRYKAVTDACSLQPDIDLLPFgdqteigergiNLSGGQRQRICVARALYQNTNIVFL 164

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1067578656 163 DEPFSALDEQLRRQI-REDMIAALRANGKSAVFVSHdREEALQYADRIAVMKQG 215
Cdd:cd03290   165 DDPFSALDIHLSDHLmQEGILKFLQDDKRTLVLVTH-KLQYLPHADWIIAMKDG 217
PRK13539 PRK13539
cytochrome c biogenesis protein CcmA; Provisional
 18-197 2.44e-22

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 237421 [Multi-domain]  Cd Length: 207  Bit Score: 93.01  E-value: 2.44e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  18 PVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRERrLGYLVQEGVLFPHLTV 97
Cdd:PRK13539   16 VLFSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGDI----DDPDVAEA-CHYLGHRNAMKPALTV 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  98 YRNIA-----YGlgngkgrtaQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDEQ 172
Cdd:PRK13539   91 AENLEfwaafLG---------GEELDIAAALEAVGLAPLAHLPFGYLSAGQKRRVALARLLVSNRPIWILDEPTAALDAA 161

                         170       180
                  ....*....|....*....|....*
gi 1067578656 173 LRRQIrEDMIAALRANGKSAVFVSH 197
Cdd:PRK13539  162 AVALF-AELIRAHLAQGGIVIAATH 185
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
 15-231 3.23e-22

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 97.62  E-value: 3.23e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  15 QNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNTNL------------PVRERRL 82
Cdd:PRK10261   27 QKIAAVRNLSFSLQRGETLAIVGESGSGKSVTALALMRLLEQAGGLVQCDKMLLRRRSRQVielseqsaaqmrHVRGADM 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  83 GYLVQEGV--LFPHLTVYRNIAYGL----GNGKGRTAQERQRieaMLELTGISE---LAGRYPHELSGGQQQRVALARAL 153
Cdd:PRK10261  107 AMIFQEPMtsLNPVFTVGEQIAESIrlhqGASREEAMVEAKR---MLDQVRIPEaqtILSRYPHQLSGGMRQRVMIAMAL 183

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1067578656 154 APDPELILLDEPFSALDEQLRRQIREdMIAALRANGKSAV-FVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPA 231
Cdd:PRK10261  184 SCRPAVLIADEPTTALDVTIQAQILQ-LIKVLQKEMSMGViFITHDMGVVAEIADRVLVMYQGEAVETGSVEQIFHAPQ 261
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
 18-217 3.38e-22

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 97.38  E-value: 3.38e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  18 PVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfskNTNLP----------VRERR------ 81
Cdd:PRK10762  266 PGVNDVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEV---VTRSPqdglangivyISEDRkrdglv 342

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  82 LGYLVQEGVLFPHLTVYRNIAYGLgngkgRTAQERQRIEAMLELTGIselagRYPH------ELSGGQQQRVALARALAP 155
Cdd:PRK10762  343 LGMSVKENMSLTALRYFSRAGGSL-----KHADEQQAVSDFIRLFNI-----KTPSmeqaigLLSGGNQQKVAIARGLMT 412

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1067578656 156 DPELILLDEPFSALDEQLRRQIReDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRI 217
Cdd:PRK10762  413 RPKVLILDEPTRGVDVGAKKEIY-QLINQFKAEGLSIILVSSEMPEVLGMSDRILVMHEGRI 473
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 2-215 9.43e-22

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 97.01  E-value: 9.43e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656    2 TAALHIGHLSKSFQNT--PVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFsknTNLPVRE 79
Cdd:TIGR01257 1935 TDILRLNELTKVYSGTssPAVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSIL---TNISDVH 2011

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   80 RRLGYLVQEGVLFPHLTvYRNIAYGLGNGKGRTAQERQRIEAM-LELTGISELAGRYPHELSGGQQQRVALARALAPDPE 158
Cdd:TIGR01257 2012 QNMGYCPQFDAIDDLLT-GREHLYLYARLRGVPAEEIEKVANWsIQSLGLSLYADRLAGTYSGGNKRKLSTAIALIGCPP 2090

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1067578656  159 LILLDEPFSALDEQLRRQIREDMIAALRaNGKSAVFVSHDREEALQYADRIAVMKQG 215
Cdd:TIGR01257 2091 LVLLDEPTTGMDPQARRMLWNTIVSIIR-EGRAVVLTSHSMEECEALCTRLAIMVKG 2146
COG4586 COG4586
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 20-218 1.09e-21

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443643 [Multi-domain]  Cd Length: 323  Bit Score: 94.00  E-value: 1.09e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  20 LNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTifskntnlPVRERRlGYLVQEGV-------LF 92
Cdd:COG4586    38 VDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEVRVLGYV--------PFKRRK-EFARRIGVvfgqrsqLW 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  93 PHLTVY------RNIaYGLGNgkgrtAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPF 166
Cdd:COG4586   109 WDLPAIdsfrllKAI-YRIPD-----AEYKKRLDELVELLDLGELLDTPVRQLSLGQRMRCELAAALLHRPKILFLDEPT 182

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1067578656 167 SALDEQLRRQIREdMIAALRANGKSAVFV-SHDRE--EALqyADRIAVMKQGRIL 218
Cdd:COG4586   183 IGLDVVSKEAIRE-FLKEYNRERGTTILLtSHDMDdiEAL--CDRVIVIDHGRII 234
3a01204 TIGR00955
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...
 20-239 1.10e-21

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273361 [Multi-domain]  Cd Length: 617  Bit Score: 96.27  E-value: 1.10e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  20 LNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPD---SGEISLSGKTIfskntNLPVRERRLGYLVQEGVLFPHLT 96
Cdd:TIGR00955  41 LKNVSGVAKPGELLAVMGSSGAGKTTLMNALAFRSPKGvkgSGSVLLNGMPI-----DAKEMRAISAYVQQDDLFIPTLT 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  97 VYRNIAYG----LGNgKGRTAQERQRIEAMLELTGISELA-------GRYpHELSGGQQQRVALARALAPDPELILLDEP 165
Cdd:TIGR00955 116 VREHLMFQahlrMPR-RVTKKEKRERVDEVLQALGLRKCAntrigvpGRV-KGLSGGERKRLAFASELLTDPPLLFCDEP 193

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 166 FSALDEQLRRQIredmIAALRA---NGKSAVFVSHD-REEALQYADRIAVMKQGRILQTASPHEL--------YRQPADL 233
Cdd:TIGR00955 194 TSGLDSFMAYSV----VQVLKGlaqKGKTIICTIHQpSSELFELFDKIILMAEGRVAYLGSPDQAvpffsdlgHPCPENY 269


                  ....*.
gi 1067578656 234 DAALFI 239
Cdd:TIGR00955 270 NPADFY 275
dppD PRK11022
dipeptide transporter ATP-binding subunit; Provisional
 3-230 1.35e-21

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 182906 [Multi-domain]  Cd Length: 326  Bit Score: 93.65  E-value: 1.35e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   3 AALHIGHLSKSF--QNTP--VLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFeqpdsgeISLSGKTI-----FSKN- 72
Cdd:PRK11022    2 ALLNVDKLSVHFgdESAPfrAVDRISYSVKQGEVVGIVGESGSGKSVSSLAIMGL-------IDYPGRVMaekleFNGQd 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  73 -TNLPVRERR------LGYLVQEGV--LFPHLTVYRNIAYGL-----GNGKGRtaqeRQRIEAMLELTGISELAGR---Y 135
Cdd:PRK11022   75 lQRISEKERRnlvgaeVAMIFQDPMtsLNPCYTVGFQIMEAIkvhqgGNKKTR----RQRAIDLLNQVGIPDPASRldvY 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 136 PHELSGGQQQRVALARALAPDPELILLDEPFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQG 215
Cdd:PRK11022  151 PHQLSGGMSQRVMIAMAIACRPKLLIADEPTTALDVTIQAQIIELLLELQQKENMALVLITHDLALVAEAAHKIIVMYAG 230

                         250
                  ....*....|....*
gi 1067578656 216 RILQTASPHELYRQP 230
Cdd:PRK11022  231 QVVETGKAHDIFRAP 245
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
21-237 1.81e-21

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 94.98  E-value: 1.81e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  21 NDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNTNLPVR-------ERRlgylVQEGVlFP 93
Cdd:PRK11288  270 EPISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLDGKPIDIRSPRDAIRagimlcpEDR----KAEGI-IP 344

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  94 HLTVYRNI----------AYGLGNGKGRTAQERQRIEAMLELTGISELAGRYpheLSGGQQQRVALARALAPDPELILLD 163
Cdd:PRK11288  345 VHSVADNInisarrhhlrAGCLINNRWEAENADRFIRSLNIKTPSREQLIMN---LSGGNQQKAILGRWLSEDMKVILLD 421

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1067578656 164 EPFSALDEQLRRQIReDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQtasphELYRQPADLDAAL 237
Cdd:PRK11288  422 EPTRGIDVGAKHEIY-NVIYELAAQGVAVLFVSSDLPEVLGVADRIVVMREGRIAG-----ELAREQATERQAL 489
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
 13-237 2.22e-21

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 95.75  E-value: 2.22e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   13 SFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNTNLpvrerrlgylvqegvLF 92
Cdd:TIGR01271  435 SLYVTPVLKNISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPSEGKIKHSGRISFSPQTSW---------------IM 499

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   93 PHlTVYRNIAYGLgngkgrtAQERQRIEAMLELTGISELAGRYPHE-----------LSGGQQQRVALARALAPDPELIL 161
Cdd:TIGR01271  500 PG-TIKDNIIFGL-------SYDEYRYTSVIKACQLEEDIALFPEKdktvlgeggitLSGGQRARISLARAVYKDADLYL 571

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1067578656  162 LDEPFSALDEQLRRQIREDMIAALRANgKSAVFVShDREEALQYADRIAVMKQGRILQTASPHELYRQPADLDAAL 237
Cdd:TIGR01271  572 LDSPFTHLDVVTEKEIFESCLCKLMSN-KTRILVT-SKLEHLKKADKILLLHEGVCYFYGTFSELQAKRPDFSSLL 645
PRK13540 PRK13540
cytochrome c biogenesis protein CcmA; Provisional
 5-199 2.42e-21

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184127 [Multi-domain]  Cd Length: 200  Bit Score: 90.39  E-value: 2.42e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfskNTNLPVRERRLGY 84
Cdd:PRK13540    2 LDVIELDFDYHDQPLLQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQSI---KKDLCTYQKQLCF 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  85 LVQEGVLFPHLTVYRNIAYGLgngkgRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDE 164
Cdd:PRK13540   79 VGHRSGINPYLTLRENCLYDI-----HFSPGAVGITELCRLFSLEHLIDYPCGLLSSGQKRQVALLRLWMSKAKLWLLDE 153

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1067578656 165 PFSALDEQLRRQIREDmIAALRANGKSAVFVSHDR 199
Cdd:PRK13540  154 PLVALDELSLLTIITK-IQEHRAKGGAVLLTSHQD 187
hmuV PRK13547
heme ABC transporter ATP-binding protein;
5-228 2.88e-21

heme ABC transporter ATP-binding protein;


Pssm-ID: 184132 [Multi-domain]  Cd Length: 272  Bit Score: 91.81  E-value: 2.88e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGfEQPDS---------GEISLSGKTIFSKNTNL 75
Cdd:PRK13547    2 LTADHLHVARRHRAILRDLSLRIEPGRVTALLGRNGAGKSTLLKALAG-DLTGGgaprgarvtGDVTLNGEPLAAIDAPR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  76 PVR---------ERRLGYLVQEGVL---FPHLTvyrniayglgNGKGRTAQERQRIEAMLELTGISELAGRYPHELSGGQ 143
Cdd:PRK13547   81 LARlravlpqaaQPAFAFSAREIVLlgrYPHAR----------RAGALTHRDGEIAWQALALAGATALVGRDVTTLSGGE 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 144 QQRVALARALA---------PDPELILLDEPFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQ 214
Cdd:PRK13547  151 LARVQFARVLAqlwpphdaaQPPRYLLLDEPTAALDLAHQHRLLDTVRRLARDWNLGVLAIVHDPNLAARHADRIAMLAD 230

                         250
                  ....*....|....
gi 1067578656 215 GRILQTASPHELYR 228
Cdd:PRK13547  231 GAIVAHGAPADVLT 244
PvdE COG4615
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ...
 23-226 5.98e-21

ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];


Pssm-ID: 443659 [Multi-domain]  Cd Length: 547  Bit Score: 93.71  E-value: 5.98e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  23 ISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNtnlpvRE--RRLGYLV-QEGVLFPHLtvyr 99
Cdd:COG4615   351 IDLTIRRGELVFIVGGNGSGKSTLAKLLTGLYRPESGEILLDGQPVTADN-----REayRQLFSAVfSDFHLFDRL---- 421

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 100 niaYGLGNgkgrtAQERQRIEAMLELTGISEL----AGRY-PHELSGGQQQRVALARALAPDPELILLDEPFSALDEQLR 174
Cdd:COG4615   422 ---LGLDG-----EADPARARELLERLELDHKvsveDGRFsTTDLSQGQRKRLALLVALLEDRPILVFDEWAADQDPEFR 493

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1067578656 175 RQIREDMIAALRANGKSAVFVSHDReealQY---ADRIAVMKQGRILQTASPHEL 226
Cdd:COG4615   494 RVFYTELLPELKARGKTVIAISHDD----RYfdlADRVLKMDYGKLVELTGPAAL 544
ABC_CcmA_heme_exporter cd03231
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ...
 19-197 7.31e-21

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.


Pssm-ID: 213198 [Multi-domain]  Cd Length: 201  Bit Score: 89.09  E-value: 7.31e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  19 VLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfskNTNLPVRERRLGYLVQEGVLFPHLTVY 98
Cdd:cd03231    15 LFSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPL---DFQRDSIARGLLYLGHAPGIKTTLSVL 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  99 RNIAYglgngkGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDEQLRRQIR 178
Cdd:cd03231    92 ENLRF------WHADHSDEQVEEALARVGLNGFEDRPVAQLSAGQQRRVALARLLLSGRPLWILDEPTTALDKAGVARFA 165

                         170
                  ....*....|....*....
gi 1067578656 179 EDMiAALRANGKSAVFVSH 197
Cdd:cd03231   166 EAM-AGHCARGGMVVLTTH 183
znuC PRK09544
high-affinity zinc transporter ATPase; Reviewed
 1-198 8.41e-21

high-affinity zinc transporter ATPase; Reviewed


Pssm-ID: 181939 [Multi-domain]  Cd Length: 251  Bit Score: 90.17  E-value: 8.41e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   1 MTAALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTifskntnlpvrer 80
Cdd:PRK09544    1 MTSLVSLENVSVSFGQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVIKRNGKL------------- 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  81 RLGYLVQEGVLFPH--LTVYRNIAYGLGNGKGRTAQERQRIEAmleltgiSELAGRYPHELSGGQQQRVALARALAPDPE 158
Cdd:PRK09544   68 RIGYVPQKLYLDTTlpLTVNRFLRLRPGTKKEDILPALKRVQA-------GHLIDAPMQKLSGGETQRVLLARALLNRPQ 140

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1067578656 159 LILLDEPFSALDEQLRRQIReDMIAALRANGKSAVF-VSHD 198
Cdd:PRK09544  141 LLVLDEPTQGVDVNGQVALY-DLIDQLRRELDCAVLmVSHD 180
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
 9-210 1.78e-20

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 92.49  E-value: 1.78e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   9 HLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLsGKTIfskntnlpvrerRLGYLVQE 88
Cdd:PRK11819  329 NLSKSFGDRLLIDDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTIKI-GETV------------KLAYVDQS 395

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  89 -GVLFPHLTVYRNIAYG-----LG-------------NGKGRTAQERqrieamleltgiselAGryphELSGGQQQRVAL 149
Cdd:PRK11819  396 rDALDPNKTVWEEISGGldiikVGnreipsrayvgrfNFKGGDQQKK---------------VG----VLSGGERNRLHL 456

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1067578656 150 ARALAPDPELILLDEPFSALD-EQLRRQirEDmiaALRANGKSAVFVSHDReealQYADRIA 210
Cdd:PRK11819  457 AKTLKQGGNVLLLDEPTNDLDvETLRAL--EE---ALLEFPGCAVVISHDR----WFLDRIA 509
ABCD_peroxisomal_ALDP cd03223
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ...
 15-209 4.95e-20

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).


Pssm-ID: 213190 [Multi-domain]  Cd Length: 166  Bit Score: 85.67  E-value: 4.95e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  15 QNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISL--SGKTIFskntnLPVRerrlGYLVQeGVLf 92
Cdd:cd03223    12 DGRVLLKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGLWPWGSGRIGMpeGEDLLF-----LPQR----PYLPL-GTL- 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  93 phltvyrniayglgngkgrtaqeRQRIeamleltgiselagRYP--HELSGGQQQRVALARALAPDPELILLDEPFSALD 170
Cdd:cd03223    81 -----------------------REQL--------------IYPwdDVLSGGEQQRLAFARLLLHKPKFVFLDEATSALD 123

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1067578656 171 EQLRRQIREdmiaALRANGKSAVFVSHdREEALQYADRI 209
Cdd:cd03223   124 EESEDRLYQ----LLKELGITVISVGH-RPSLWKFHDRV 157
PRK10522 PRK10522
multidrug transporter membrane component/ATP-binding component; Provisional
 20-217 6.30e-20

multidrug transporter membrane component/ATP-binding component; Provisional


Pssm-ID: 236707 [Multi-domain]  Cd Length: 547  Bit Score: 90.80  E-value: 6.30e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  20 LNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNtnlPVRERRLGYLVQEGV-LFPHLTvy 98
Cdd:PRK10522  339 VGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVTAEQ---PEDYRKLFSAVFTDFhLFDQLL-- 413

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  99 rniayglgnGKGRTAQERQRIEAMLELTGISE----LAGRYPH-ELSGGQQQRVALARALAPDPELILLDEPFSALDEQL 173
Cdd:PRK10522  414 ---------GPEGKPANPALVEKWLERLKMAHklelEDGRISNlKLSKGQKKRLALLLALAEERDILLLDEWAADQDPHF 484

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1067578656 174 RRQIREDMIAALRANGKSAVFVSHDrEEALQYADRIAVMKQGRI 217
Cdd:PRK10522  485 RREFYQVLLPLLQEMGKTIFAISHD-DHYFIHADRLLEMRNGQL 527
PRK13657 PRK13657
glucan ABC transporter ATP-binding protein/ permease;
9-226 1.16e-19

glucan ABC transporter ATP-binding protein/ permease;


Pssm-ID: 184214 [Multi-domain]  Cd Length: 588  Bit Score: 90.02  E-value: 1.16e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   9 HLSKSFQNT-PVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsKNTNLPVRERRLGYLVQ 87
Cdd:PRK13657  339 DVSFSYDNSrQGVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDGTDI--RTVTRASLRRNIAVVFQ 416

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  88 EGVLFPhltvyRNIAYGLGNGKG-------RTAQERQRIEAMLE--LTGISELAGRYPHELSGGQQQRVALARALAPDPE 158
Cdd:PRK13657  417 DAGLFN-----RSIEDNIRVGRPdatdeemRAAAERAQAHDFIErkPDGYDTVVGERGRQLSGGERQRLAIARALLKDPP 491

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1067578656 159 LILLDEPFSALDEQLRRQIREdMIAALRANgkSAVFVSHDREEALQYADRIAVMKQGRILQTASPHEL 226
Cdd:PRK13657  492 ILILDEATSALDVETEAKVKA-ALDELMKG--RTTFIIAHRLSTVRNADRILVFDNGRVVESGSFDEL 556
oppD PRK09473
oligopeptide transporter ATP-binding component; Provisional
 21-231 1.46e-19

oligopeptide transporter ATP-binding component; Provisional


Pssm-ID: 181888 [Multi-domain]  Cd Length: 330  Bit Score: 87.86  E-value: 1.46e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  21 NDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPD---SGEISLSGKTIFskntNLPvrERRLGYLVQEGV------- 90
Cdd:PRK09473   33 NDLNFSLRAGETLGIVGESGSGKSQTAFALMGLLAANgriGGSATFNGREIL----NLP--EKELNKLRAEQIsmifqdp 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  91 ---LFPHLTVYRNIAYGL----GNGKGRTAQERQRieaMLELTGISELAGR---YPHELSGGQQQRVALARALAPDPELI 160
Cdd:PRK09473  107 mtsLNPYMRVGEQLMEVLmlhkGMSKAEAFEESVR---MLDAVKMPEARKRmkmYPHEFSGGMRQRVMIAMALLCRPKLL 183

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1067578656 161 LLDEPFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPA 231
Cdd:PRK09473  184 IADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGNARDVFYQPS 254
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 6-170 1.99e-19

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 89.22  E-value: 1.99e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   6 HIGHLSKSFQ-NTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLS-GKTIfskntnlpvrerrlG 83
Cdd:TIGR03719   6 TMNRVSKVVPpKKEILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKDFNGEARPQpGIKV--------------G 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  84 YLVQEGVLFPHLTVYRNIAYGLGNGKG--------------------RTAQERQRIEAMLELTGISEL---------AGR 134
Cdd:TIGR03719  72 YLPQEPQLDPTKTVRENVEEGVAEIKDaldrfneisakyaepdadfdKLAAEQAELQEIIDAADAWDLdsqleiamdALR 151

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 1067578656 135 YP------HELSGGQQQRVALARALAPDPELILLDEPFSALD 170
Cdd:TIGR03719 152 CPpwdadvTKLSGGERRRVALCRLLLSKPDMLLLDEPTNHLD 193
PLN03211 PLN03211
ABC transporter G-25; Provisional
 11-218 2.15e-19

ABC transporter G-25; Provisional


Pssm-ID: 215634 [Multi-domain]  Cd Length: 659  Bit Score: 89.55  E-value: 2.15e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  11 SKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDsgeiSLSGKTIfsKNTNLPVRE--RRLGYLVQE 88
Cdd:PLN03211   75 TRQIQERTILNGVTGMASPGEILAVLGPSGSGKSTLLNALAGRIQGN----NFTGTIL--ANNRKPTKQilKRTGFVTQD 148

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  89 GVLFPHLTVYRNIAYG--LGNGKGRTAQERQRI-EAMLELTGISE-----LAGRYPHELSGGQQQRVALARALAPDPELI 160
Cdd:PLN03211  149 DILYPHLTVRETLVFCslLRLPKSLTKQEKILVaESVISELGLTKcentiIGNSFIRGISGGERKRVSIAHEMLINPSLL 228

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1067578656 161 LLDEPFSALDEQLRRQIREDMiAALRANGKSAVFVSHD-REEALQYADRIAVMKQGRIL 218
Cdd:PLN03211  229 ILDEPTSGLDATAAYRLVLTL-GSLAQKGKTIVTSMHQpSSRVYQMFDSVLVLSEGRCL 286
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
 4-217 3.00e-19

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 88.80  E-value: 3.00e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   4 ALHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISlsgktiFSKNTNlpvrerrLG 83
Cdd:PRK15064  319 ALEVENLTKGFDNGPLFKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTVK------WSENAN-------IG 385

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  84 YLVQEGV--------LFPHLTVYRniayglgngkgRTAQERQRIEAML-ELTGISELAGRYPHELSGGQQQRVALARALA 154
Cdd:PRK15064  386 YYAQDHAydfendltLFDWMSQWR-----------QEGDDEQAVRGTLgRLLFSQDDIKKSVKVLSGGEKGRMLFGKLMM 454

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1067578656 155 PDPELILLDEPFSALD-EQLrrqirEDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRI 217
Cdd:PRK15064  455 QKPNVLVMDEPTNHMDmESI-----ESLNMALEKYEGTLIFVSHDREFVSSLATRIIEITPDGV 513
GguA NF040905
sugar ABC transporter ATP-binding protein;
11-220 3.21e-19

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 88.31  E-value: 3.21e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  11 SKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAG------FEqpdsGEISLSGKTIFSKNTNlpvRERRLGY 84
Cdd:NF040905    8 TKTFPGVKALDDVNLSVREGEIHALCGENGAGKSTLMKVLSGvyphgsYE----GEILFDGEVCRFKDIR---DSEALGI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  85 LV--QEGVLFPHLTVYRNIAygLGNGKGRT-----AQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDP 157
Cdd:NF040905   81 VIihQELALIPYLSIAENIF--LGNERAKRgvidwNETNRRARELLAKVGLDESPDTLVTDIGVGKQQLVEIAKALSKDV 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1067578656 158 ELILLDEPFSALDEQLRRQIReDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQT 220
Cdd:NF040905  159 KLLILDEPTAALNEEDSAALL-DLLLELKAQGITSIIISHKLNEIRRVADSITVLRDGRTIET 220
ABC_RNaseL_inhibitor_domain2 cd03237
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 20-211 3.67e-19

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213204 [Multi-domain]  Cd Length: 246  Bit Score: 85.54  E-value: 3.67e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  20 LNDISLSLDPG-----EILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNTNLPVRerrlgylvQEGvlfph 94
Cdd:cd03237    10 LGEFTLEVEGGsisesEVIGILGPNGIGKTTFIKMLAGVLKPDEGDIEIELDTVSYKPQYIKAD--------YEG----- 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  95 lTVyRNIAYGLGNGKGRTAQERQRIEAMLELTGISElagRYPHELSGGQQQRVALARALAPDPELILLDEPFSALD-EQl 173
Cdd:cd03237    77 -TV-RDLLSSITKDFYTHPYFKTEIAKPLQIEQILD---REVPELSGGELQRVAIAACLSKDADIYLLDEPSAYLDvEQ- 150

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1067578656 174 rRQIREDMIAALRANGKSAVFV-SHDREEALQYADRIAV 211
Cdd:cd03237   151 -RLMASKVIRRFAENNEKTAFVvEHDIIMIDYLADRLIV 188
PRK13543 PRK13543
heme ABC exporter ATP-binding protein CcmA;
10-193 4.17e-19

heme ABC exporter ATP-binding protein CcmA;


Pssm-ID: 184129 [Multi-domain]  Cd Length: 214  Bit Score: 84.52  E-value: 4.17e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  10 LSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNtnlpvRERRLGYLVQEG 89
Cdd:PRK13543   17 LAFSRNEEPVFGPLDFHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQIQIDGKTATRGD-----RSRFMAYLGHLP 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  90 VLFPHLTVYRNIAYgLGNGKGRTAQerQRIEAMLELTGISELAGRYPHELSGGQQQRVALARA-LAPDPeLILLDEPFSA 168
Cdd:PRK13543   92 GLKADLSTLENLHF-LCGLHGRRAK--QMPGSALAIVGLAGYEDTLVRQLSAGQKKRLALARLwLSPAP-LWLLDEPYAN 167

                         170       180
                  ....*....|....*....|....*
gi 1067578656 169 LDEQLRRQIREDMIAALRANGKSAV 193
Cdd:PRK13543  168 LDLEGITLVNRMISAHLRGGGAALV 192
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
 20-237 5.38e-19

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 87.96  E-value: 5.38e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  20 LNDISLSLDPGEILFIIGASGCGKTTLLRCLAG-FEQPDSGEISLSGKTIFSKNtnlPVRERRLGY-LVQE-----GVLf 92
Cdd:TIGR02633 276 VDDVSFSLRRGEILGVAGLVGAGRTELVQALFGaYPGKFEGNVFINGKPVDIRN---PAQAIRAGIaMVPEdrkrhGIV- 351

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  93 PHLTVYRNIAYGLGN---GKGR--TAQERQRIEAmleltGISELAGRYPH------ELSGGQQQRVALARALAPDPELIL 161
Cdd:TIGR02633 352 PILGVGKNITLSVLKsfcFKMRidAAAELQIIGS-----AIQRLKVKTASpflpigRLSGGNQQKAVLAKMLLTNPRVLI 426

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1067578656 162 LDEPFSALDEQLRRQIREdMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELyRQPADLDAAL 237
Cdd:TIGR02633 427 LDEPTRGVDVGAKYEIYK-LINQLAQEGVAIIVVSSELAEVLGLSDRVLVIGEGKLKGDFVNHAL-TQEQVLAAAL 500
MK0520 COG2401
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ...
 17-204 5.86e-19

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];


Pssm-ID: 441957 [Multi-domain]  Cd Length: 222  Bit Score: 84.24  E-value: 5.86e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  17 TPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFE--QPDSGEISLSGKTIfskNTNLPVRERrlgylvqegvlfph 94
Cdd:COG2401    43 RYVLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGALkgTPVAGCVDVPDNQF---GREASLIDA-------------- 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  95 ltVYRniayglgngKGRTAQERQRIEAMleltGISE--LAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDEQ 172
Cdd:COG2401   106 --IGR---------KGDFKDAVELLNAV----GLSDavLWLRRFKELSTGQKFRFRLALLLAERPKLLVIDEFCSHLDRQ 170

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1067578656 173 LRRQIREDMIAALRANGKSAVFVSH--DREEALQ 204
Cdd:COG2401   171 TAKRVARNLQKLARRAGITLVVATHhyDVIDDLQ 204
nikD PRK10418
nickel transporter ATP-binding protein NikD; Provisional
 18-231 8.45e-19

nickel transporter ATP-binding protein NikD; Provisional


Pssm-ID: 236688 [Multi-domain]  Cd Length: 254  Bit Score: 84.37  E-value: 8.45e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  18 PVLNDISLSLDPGEILFIIGASGCGKTtlLRCLA-------GFEQPdSGEISLSGKTIFSKNtnlpVRERRLGYLVQEG- 89
Cdd:PRK10418   17 PLVHGVSLTLQRGRVLALVGGSGSGKS--LTCAAalgilpaGVRQT-AGRVLLDGKPVAPCA----LRGRKIATIMQNPr 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  90 VLFPHLTVYRNIAYGLGNGKGRTAQERQRIEAMlELTGISE---LAGRYPHELSGGQQQRVALARALAPDPELILLDEPF 166
Cdd:PRK10418   90 SAFNPLHTMHTHARETCLALGKPADDATLTAAL-EAVGLENaarVLKLYPFEMSGGMLQRMMIALALLCEAPFIIADEPT 168

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1067578656 167 SALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPA 231
Cdd:PRK10418  169 TDLDVVAQARILDLLESIVQKRALGMLLVTHDMGVVARLADDVAVMSHGRIVEQGDVETLFNAPK 233
ABCC_NFT1 cd03369
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ...
 18-223 1.12e-18

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213269 [Multi-domain]  Cd Length: 207  Bit Score: 83.23  E-value: 1.12e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  18 PVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsKNTNLPVRERRLGYLVQEGVLFPHlTV 97
Cdd:cd03369    22 PVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDI--STIPLEDLRSSLTIIPQDPTLFSG-TI 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  98 YRNI-AYGlgngkgrtAQERQRIEAMLELTGISElagryphELSGGQQQRVALARALAPDPELILLDEPFSALDEQ---- 172
Cdd:cd03369    99 RSNLdPFD--------EYSDEEIYGALRVSEGGL-------NLSQGQRQLLCLARALLKRPRVLVLDEATASIDYAtdal 163

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1067578656 173 LRRQIREDMiaalraNGKSAVFVSHDREEALQYaDRIAVMKQGRILQTASP 223
Cdd:cd03369   164 IQKTIREEF------TNSTILTIAHRLRTIIDY-DKILVMDAGEVKEYDHP 207
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
 5-217 4.57e-18

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 85.17  E-value: 4.57e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKsfQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNTN--------LP 76
Cdd:PRK10982  251 LEVRNLTS--LRQPSIRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKKINNHNANeainhgfaLV 328

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  77 VRERR----LGYL-VQEGVLFPHLTVYRNiAYGLGNGKGRTAQERQRIEAM-LELTGISELAGryphELSGGQQQRVALA 150
Cdd:PRK10982  329 TEERRstgiYAYLdIGFNSLISNIRNYKN-KVGLLDNSRMKSDTQWVIDSMrVKTPGHRTQIG----SLSGGNQQKVIIG 403

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1067578656 151 RALAPDPELILLDEPFSALDEQLRRQIREdMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRI 217
Cdd:PRK10982  404 RWLLTQPEILMLDEPTRGIDVGAKFEIYQ-LIAELAKKDKGIIIISSEMPELLGITDRILVMSNGLV 469
ABCC_MRP_domain2 cd03244
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ...
 18-223 4.69e-18

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213211 [Multi-domain]  Cd Length: 221  Bit Score: 81.77  E-value: 4.69e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  18 PVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsknTNLPVRE--RRLGYLVQEGVLFPHl 95
Cdd:cd03244    18 PVLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIDGVDI----SKIGLHDlrSRISIIPQDPVLFSG- 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  96 TVYRNIA-YGLgngkgrtAQERQRIEAmLELTG----ISELAGRYPHE-------LSGGQQQRVALARALAPDPELILLD 163
Cdd:cd03244    93 TIRSNLDpFGE-------YSDEELWQA-LERVGlkefVESLPGGLDTVveeggenLSVGQRQLLCLARALLRKSKILVLD 164

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1067578656 164 EPFSALDEQLRRQIREdmiaALRANGKSA--VFVSHdREEALQYADRIAVMKQGRILQTASP 223
Cdd:cd03244   165 EATASVDPETDALIQK----TIREAFKDCtvLTIAH-RLDTIIDSDRILVLDKGRVVEFDSP 221
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
 10-220 5.61e-18

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 84.78  E-value: 5.61e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  10 LSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNTNLPVrERRLGYLVQEG 89
Cdd:PRK10982    4 ISKSFPGVKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGKEIDFKSSKEAL-ENGISMVHQEL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  90 VLFPHLTVYRNIAYGLGNGKGRTAQER---QRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPF 166
Cdd:PRK10982   83 NLVLQRSVMDNMWLGRYPTKGMFVDQDkmyRDTKAIFDELDIDIDPRAKVATLSVSQMQMIEIAKAFSYNAKIVIMDEPT 162

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1067578656 167 SALDEQLRRQIREdMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQT 220
Cdd:PRK10982  163 SSLTEKEVNHLFT-IIRKLKERGCGIVYISHKMEEIFQLCDEITILRDGQWIAT 215
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
20-198 8.34e-18

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 84.47  E-value: 8.34e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  20 LNDISLSLDPGEI-----LFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIF-----SKNTNLPVRErrlgYLVQEG 89
Cdd:PRK13409  350 LGDFSLEVEGGEIyegevIGIVGPNGIGKTTFAKLLAGVLKPDEGEVDPELKISYkpqyiKPDYDGTVED----LLRSIT 425

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  90 VLFPHLTVYRNIAYGLGngkgrtaqerqrIEAMLEltgiselagRYPHELSGGQQQRVALARALAPDPELILLDEPFSAL 169
Cdd:PRK13409  426 DDLGSSYYKSEIIKPLQ------------LERLLD---------KNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHL 484

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1067578656 170 D-EQ-------LRRQIREdmiaalraNGKSAVFVSHD 198
Cdd:PRK13409  485 DvEQrlavakaIRRIAEE--------REATALVVDHD 513
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
 19-217 9.59e-18

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 84.21  E-value: 9.59e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  19 VLNDISLSLDPGEILFIIGASGCGKTTLLRCLAG-FEQPDSGEISLSGKTIFSKNtnlPVRERRLGY-LVQE-----GVL 91
Cdd:PRK13549  277 RVDDVSFSLRRGEILGIAGLVGAGRTELVQCLFGaYPGRWEGEIFIDGKPVKIRN---PQQAIAQGIaMVPEdrkrdGIV 353

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  92 fPHLTVYRNIAYG-LGNGKGRTaqerqRIEAMLELTGISE----LAGRYPH------ELSGGQQQRVALARALAPDPELI 160
Cdd:PRK13549  354 -PVMGVGKNITLAaLDRFTGGS-----RIDDAAELKTILEsiqrLKVKTASpelaiaRLSGGNQQKAVLAKCLLLNPKIL 427

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1067578656 161 LLDEPFSALDEQLRRQIREdMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRI 217
Cdd:PRK13549  428 ILDEPTRGIDVGAKYEIYK-LINQLVQQGVAIIVISSELPEVLGLSDRVLVMHEGKL 483
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
 5-227 3.75e-17

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 82.69  E-value: 3.75e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSksFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGfEQP-DSGEISLSGKTIFSKNTNLPVRERR-- 81
Cdd:PRK11147    6 IHGAWLS--FSDAPLLDNAELHIEDNERVCLVGRNGAGKSTLMKILNG-EVLlDDGRIIYEQDLIVARLQQDPPRNVEgt 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  82 -LGYlVQEGV--LFPHLTVYRNIAYGLGN-------GKGRTAQER----------QRIEAMLELTGIS---ELAgryphE 138
Cdd:PRK11147   83 vYDF-VAEGIeeQAEYLKRYHDISHLVETdpseknlNELAKLQEQldhhnlwqleNRINEVLAQLGLDpdaALS-----S 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 139 LSGGQQQRVALARALAPDPELILLDEPFSALD-------EQLrrqiredmiaaLRANGKSAVFVSHDREEALQYADRIAV 211
Cdd:PRK11147  157 LSGGWLRKAALGRALVSNPDVLLLDEPTNHLDietiewlEGF-----------LKTFQGSIIFISHDRSFIRNMATRIVD 225

                         250
                  ....*....|....*.
gi 1067578656 212 MKQGRILQTASPHELY 227
Cdd:PRK11147  226 LDRGKLVSYPGNYDQY 241
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
 18-226 4.03e-17

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 83.07  E-value: 4.03e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   18 PVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFskntnLPVRERRLGYLVQEGVLFphltv 97
Cdd:TIGR00957  652 PTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVHMKGSVAY-----VPQQAWIQNDSLRENILF----- 721

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   98 yrniayglgngkGRTAQE---RQRIEAMLELTGISELAGRYPHE-------LSGGQQQRVALARALAPDPELILLDEPFS 167
Cdd:TIGR00957  722 ------------GKALNEkyyQQVLEACALLPDLEILPSGDRTEigekgvnLSGGQKQRVSLARAVYSNADIYLFDDPLS 789

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  168 ALDEQLRRQIREDMIAALRA-NGKSAVFVSHDReEALQYADRIAVMKQGRILQTASPHEL 226
Cdd:TIGR00957  790 AVDAHVGKHIFEHVIGPEGVlKNKTRILVTHGI-SYLPQVDVIIVMSGGKISEMGSYQEL 848
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
 13-202 7.82e-17

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 81.21  E-value: 7.82e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  13 SFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAG-FEQPDSGEISL------SGKTIFSKntnlpvrERRLGYL 85
Cdd:PRK10938  269 SYNDRPILHNLSWQVNPGEHWQIVGPNGAGKSTLLSLITGdHPQGYSNDLTLfgrrrgSGETIWDI-------KKHIGYV 341

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  86 VQEgvlfPHL-----TVYRN-IAYGLGNGKG--RTAQERQRIEAM--LELTGISELAGRYP-HELSGGQQQRVALARALA 154
Cdd:PRK10938  342 SSS----LHLdyrvsTSVRNvILSGFFDSIGiyQAVSDRQQKLAQqwLDILGIDKRTADAPfHSLSWGQQRLALIVRALV 417

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1067578656 155 PDPELILLDEPFSALDEqLRRQIREDMIAALRANGKSA-VFVSHDREEA 202
Cdd:PRK10938  418 KHPTLLILDEPLQGLDP-LNRQLVRRFVDVLISEGETQlLFVSHHAEDA 465
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 20-198 9.00e-17

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 81.37  E-value: 9.00e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  20 LNDISLSLDPG-----EILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIF-----SKNTNLPVRErrlgYLvqEG 89
Cdd:COG1245   351 YGGFSLEVEGGeiregEVLGIVGPNGIGKTTFAKILAGVLKPDEGEVDEDLKISYkpqyiSPDYDGTVEE----FL--RS 424

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  90 VLFPHLT---VYRNIAYGLGngkgrtaqerqrIEAMLEltgiselagRYPHELSGGQQQRVALARALAPDPELILLDEPF 166
Cdd:COG1245   425 ANTDDFGssyYKTEIIKPLG------------LEKLLD---------KNVKDLSGGELQRVAIAACLSRDADLYLLDEPS 483

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1067578656 167 SALD-EQ-------LRRQIREdmiaalraNGKSAVFVSHD 198
Cdd:COG1245   484 AHLDvEQrlavakaIRRFAEN--------RGKTAMVVDHD 515
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
 10-170 9.05e-17

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 81.32  E-value: 9.05e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  10 LSKSF-QNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLS-GKTIfskntnlpvrerrlGYLVQ 87
Cdd:PRK11819   12 VSKVVpPKKQILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKEFEGEARPApGIKV--------------GYLPQ 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  88 EGVLFPHLTVYRNIAYGLGNGKG--------------------RTAQERQRIEAMLELTGISEL---------AGRYPH- 137
Cdd:PRK11819   78 EPQLDPEKTVRENVEEGVAEVKAaldrfneiyaayaepdadfdALAAEQGELQEIIDAADAWDLdsqleiamdALRCPPw 157

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1067578656 138 -----ELSGGQQQRVALARALAPDPELILLDEPFSALD 170
Cdd:PRK11819  158 dakvtKLSGGERRRVALCRLLLEKPDMLLLDEPTNHLD 195
SapD COG4170
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
3-286 9.66e-17

ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];


Pssm-ID: 443330 [Multi-domain]  Cd Length: 331  Bit Score: 79.95  E-value: 9.66e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   3 AALHIGHLSKSFQnTP-----VLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFeQPDSGEIS-----LSGKTIfskn 72
Cdd:COG4170     2 PLLDIRNLTIEID-TPqgrvkAVDRVSLTLNEGEIRGLVGESGSGKSLIAKAICGI-TKDNWHVTadrfrWNGIDL---- 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  73 TNLPVRERR------LGYLVQE--GVLFPHLTVYRNIAYGLGNG--KG----RTAQERQRIEAMLELTGI---SELAGRY 135
Cdd:COG4170    76 LKLSPRERRkiigreIAMIFQEpsSCLDPSAKIGDQLIEAIPSWtfKGkwwqRFKWRKKRAIELLHRVGIkdhKDIMNSY 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 136 PHELSGGQQQRVALARALAPDPELILLDEPFSALDEQLRRQI-RedMIAAL-RANGKSAVFVSHDREEALQYADRIAVMK 213
Cdd:COG4170   156 PHELTEGECQKVMIAMAIANQPRLLIADEPTNAMESTTQAQIfR--LLARLnQLQGTSILLISHDLESISQWADTITVLY 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 214 QGRILQTASPHELYRQP------ADLDAALFIGEGIVFPAALNA-DGTA--------DCRLG-RLP------VQsgAPAG 271
Cdd:COG4170   234 CGQTVESGPTEQILKSPhhpytkALLRSMPDFRQPLPHKSRLNTlPGSIpplqhlpiGCRLGpRCPyaqkkcVE--TPRL 311

                         330
                  ....*....|....*
gi 1067578656 272 TRgtllIRPEQFSLH 286
Cdd:COG4170   312 RK----IKGHEFACH 322
PRK15093 PRK15093
peptide ABC transporter ATP-binding protein SapD;
5-230 3.51e-16

peptide ABC transporter ATP-binding protein SapD;


Pssm-ID: 185049 [Multi-domain]  Cd Length: 330  Bit Score: 78.31  E-value: 3.51e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQNT--PV--LNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQpDSGEISlSGKTIFSKNT--NLPVR 78
Cdd:PRK15093    4 LDIRNLTIEFKTSdgWVkaVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGVTK-DNWRVT-ADRMRFDDIDllRLSPR 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  79 ERR------LGYLVQE--GVLFPHLTVYRNIAYGLGNG--KGRTAQ-----ERQRIEaMLELTGISE---LAGRYPHELS 140
Cdd:PRK15093   82 ERRklvghnVSMIFQEpqSCLDPSERVGRQLMQNIPGWtyKGRWWQrfgwrKRRAIE-LLHRVGIKDhkdAMRSFPYELT 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 141 GGQQQRVALARALAPDPELILLDEPFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRILQT 220
Cdd:PRK15093  161 EGECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLTRLNQNNNTTILLISHDLQMLSQWADKINVLYCGQTVET 240

                         250
                  ....*....|
gi 1067578656 221 ASPHELYRQP 230
Cdd:PRK15093  241 APSKELVTTP 250
ABCG_PDR_domain1 cd03233
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ...
 11-217 3.86e-16

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213200 [Multi-domain]  Cd Length: 202  Bit Score: 75.76  E-value: 3.86e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  11 SKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEqpdSGEISLSGKTIFSKNTNLPVRERRLG---YLVQ 87
Cdd:cd03233    14 GKGRSKIPILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANRT---EGNVSVEGDIHYNGIPYKEFAEKYPGeiiYVSE 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  88 EGVLFPHLTVyrniayglgngkgrtaqeRQRIEAMLELTGiselaGRYPHELSGGQQQRVALARALAPDPELILLDEPFS 167
Cdd:cd03233    91 EDVHFPTLTV------------------RETLDFALRCKG-----NEFVRGISGGERKRVSIAEALVSRASVLCWDNSTR 147

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1067578656 168 ALDEqlrrQIREDMIAALRANG---KSAVFVS--HDREEALQYADRIAVMKQGRI 217
Cdd:cd03233   148 GLDS----STALEILKCIRTMAdvlKTTTFVSlyQASDEIYDLFDKVLVLYEGRQ 198
ABCG_PDR_domain2 cd03232
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ...
 15-172 9.24e-16

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213199 [Multi-domain]  Cd Length: 192  Bit Score: 74.59  E-value: 9.24e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  15 QNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPD--SGEISLSGKtifSKNTNLPvreRRLGYLVQEGVLF 92
Cdd:cd03232    18 GKRQLLNNISGYVKPGTLTALMGESGAGKTTLLDVLAGRKTAGviTGEILINGR---PLDKNFQ---RSTGYVEQQDVHS 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  93 PHLTVYrniayglgngkgrtaqERQRIEAMLEltgiselagryphELSGGQQQRVALARALAPDPELILLDEPFSALDEQ 172
Cdd:cd03232    92 PNLTVR----------------EALRFSALLR-------------GLSVEQRKRLTIGVELAAKPSILFLDEPTSGLDSQ 142
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
 16-225 2.64e-15

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 77.38  E-value: 2.64e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   16 NTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGF------------------------EQPD-------------- 57
Cdd:PTZ00265  1180 NVPIYKDLTFSCDSKKTTAIVGETGSGKSTVMSLLMRFydlkndhhivfknehtndmtneqdYQGDeeqnvgmknvnefs 1259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   58 ----------------SGEISLSGKTIFSKNtnlpVRERR--LGYLVQEGVLFpHLTVYRNIAYGLGNGKGRTAQERQRI 119
Cdd:PTZ00265  1260 ltkeggsgedstvfknSGKILLDGVDICDYN----LKDLRnlFSIVSQEPMLF-NMSIYENIKFGKEDATREDVKRACKF 1334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  120 EAMLELtgISEL-------AGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDEQLRRQIREDMIAALRANGKSA 192
Cdd:PTZ00265  1335 AAIDEF--IESLpnkydtnVGPYGKSLSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLIEKTIVDIKDKADKTI 1412

                          250       260       270
                   ....*....|....*....|....*....|....*..
gi 1067578656  193 VFVSHdREEALQYADRIAVM----KQGRILQTASPHE 225
Cdd:PTZ00265  1413 ITIAH-RIASIKRSDKIVVFnnpdRTGSFVQAHGTHE 1448
ycf16 CHL00131
sulfate ABC transporter protein; Validated
 5-222 3.96e-15

sulfate ABC transporter protein; Validated


Pssm-ID: 214372 [Multi-domain]  Cd Length: 252  Bit Score: 74.29  E-value: 3.96e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGfeQPD----SGEISLSGKTIfsknTNLPVRER 80
Cdd:CHL00131    8 LEIKNLHASVNENEILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAG--HPAykilEGDILFKGESI----LDLEPEER 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  81 -RLGYLV--QEGVLFPHLTV--YRNIAYglgNGKgRTAQERQRIEAMLELTGISE---LAGRYPHEL--------SGGQQ 144
Cdd:CHL00131   82 aHLGIFLafQYPIEIPGVSNadFLRLAY---NSK-RKFQGLPELDPLEFLEIINEklkLVGMDPSFLsrnvnegfSGGEK 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 145 QRVALARALAPDPELILLDEPFSALDEQLRRQIREDmIAALRANGKSAVFVSHdREEALQY--ADRIAVMKQGRILQTAS 222
Cdd:CHL00131  158 KRNEILQMALLDSELAILDETDSGLDIDALKIIAEG-INKLMTSENSIILITH-YQRLLDYikPDYVHVMQNGKIIKTGD 235
PRK13541 PRK13541
cytochrome c biogenesis protein CcmA; Provisional
 16-206 9.08e-15

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184128 [Multi-domain]  Cd Length: 195  Bit Score: 71.83  E-value: 9.08e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  16 NTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEislsgktIFSKNTNL-PVRERRLGYLVQEGVLFPH 94
Cdd:PRK13541   12 EQKNLFDLSITFLPSAITYIKGANGCGKSSLLRMIAGIMQPSSGN-------IYYKNCNInNIAKPYCTYIGHNLGLKLE 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  95 LTVYRNIAYGlgngkGRTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDEQlR 174
Cdd:PRK13541   85 MTVFENLKFW-----SEIYNSAETLYAAIHYFKLHDLLDEKCYSLSSGMQKIVAIARLIACQSDLWLLDEVETNLSKE-N 158

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1067578656 175 RQIREDMIaALRANGKSAVFVSHDREEALQYA 206
Cdd:PRK13541  159 RDLLNNLI-VMKANSGGIVLLSSHLESSIKSA 189
PTZ00243 PTZ00243
ABC transporter; Provisional
 14-217 1.34e-14

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 75.20  E-value: 1.34e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   14 FQNTP--VLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEIslsgktifskntnlpVRERRLGYLVQEGVL 91
Cdd:PTZ00243   668 FELEPkvLLRDVSVSVPRGKLTVVLGATGSGKSTLLQSLLSQFEISEGRV---------------WAERSIAYVPQQAWI 732

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   92 FpHLTVYRNIAYGLGNGKGRTAQERQ--RIEAMLEL--TGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFS 167
Cdd:PTZ00243   733 M-NATVRGNILFFDEEDAARLADAVRvsQLEADLAQlgGGLETEIGEKGVNLSGGQKARVSLARAVYANRDVYLLDDPLS 811

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1067578656  168 ALDEQLRRQIREDMI-AALRanGKSAVFVSHdREEALQYADRIAVMKQGRI 217
Cdd:PTZ00243   812 ALDAHVGERVVEECFlGALA--GKTRVLATH-QVHVVPRADYVVALGDGRV 859
PLN03130 PLN03130
ABC transporter C family member; Provisional
 18-226 3.77e-14

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 74.00  E-value: 3.77e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   18 PVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGfEQPdsgeiSLSGKTIFSKNTnlpvrerrLGYLVQEGVLFpHLTV 97
Cdd:PLN03130   631 PTLSNINLDVPVGSLVAIVGSTGEGKTSLISAMLG-ELP-----PRSDASVVIRGT--------VAYVPQVSWIF-NATV 695

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   98 YRNIAYGLgngkgrtAQERQRIEAMLELTGISE----LAGRYPHE-------LSGGQQQRVALARALAPDPELILLDEPF 166
Cdd:PLN03130   696 RDNILFGS-------PFDPERYERAIDVTALQHdldlLPGGDLTEigergvnISGGQKQRVSMARAVYSNSDVYIFDDPL 768

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1067578656  167 SALDEQLRRQIREDMIA-ALRanGKSAVFVShDREEALQYADRIAVMKQGRILQTASPHEL 226
Cdd:PLN03130   769 SALDAHVGRQVFDKCIKdELR--GKTRVLVT-NQLHFLSQVDRIILVHEGMIKEEGTYEEL 826
PLN03232 PLN03232
ABC transporter C family member; Provisional
 18-228 4.36e-14

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 73.47  E-value: 4.36e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   18 PVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGfeqpdsgEISlsgktiFSKNTNLPVRERrLGYLVQEGVLFpHLTV 97
Cdd:PLN03232   631 PTLSDINLEIPVGSLVAIVGGTGEGKTSLISAMLG-------ELS------HAETSSVVIRGS-VAYVPQVSWIF-NATV 695

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   98 YRNIAYGlgngkgrTAQERQRIEAMLELTGISE----LAGRYPHEL-------SGGQQQRVALARALAPDPELILLDEPF 166
Cdd:PLN03232   696 RENILFG-------SDFESERYWRAIDVTALQHdldlLPGRDLTEIgergvniSGGQKQRVSMARAVYSNSDIYIFDDPL 768

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1067578656  167 SALDEQLRRQIREDMIA-ALRanGKSAVFVShDREEALQYADRIAVMKQGRILQTASPHELYR 228
Cdd:PLN03232   769 SALDAHVAHQVFDSCMKdELK--GKTRVLVT-NQLHFLPLMDRIILVSEGMIKEEGTFAELSK 828
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
 5-212 6.55e-14

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 72.35  E-value: 6.55e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSgktiFSKNTNLPVRErrLGY 84
Cdd:PRK10938    4 LQISQGTFRLSDTKTLQLPSLTLNAGDSWAFVGANGSGKSALARALAGELPLLSGERQSQ----FSHITRLSFEQ--LQK 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  85 LVQEgvlfphlTVYRNIAYGLGNGK---GRTAQE--------RQRIEAMLELTGISELAGRYPHELSGGQQQRVALARAL 153
Cdd:PRK10938   78 LVSD-------EWQRNNTDMLSPGEddtGRTTAEiiqdevkdPARCEQLAQQFGITALLDRRFKYLSTGETRKTLLCQAL 150

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1067578656 154 APDPELILLDEPFSALDEQLRRQIREdMIAALRANGKSAVFVSHDREEALQYADRIAVM 212
Cdd:PRK10938  151 MSEPDLLILDEPFDGLDVASRQQLAE-LLASLHQSGITLVLVLNRFDEIPDFVQFAGVL 208
PTZ00243 PTZ00243
ABC transporter; Provisional
 19-226 6.95e-13

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 69.81  E-value: 6.95e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   19 VLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNtnlpVRE--RRLGYLVQEGVLFPHlT 96
Cdd:PTZ00243  1325 VLRGVSFRIAPREKVGIVGRTGSGKSTLLLTFMRMVEVCGGEIRVNGREIGAYG----LRElrRQFSMIPQDPVLFDG-T 1399

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   97 VYRNI-------------AYGLGNGKGRTAQERQRIEAMLeLTGISelagryphELSGGQQQRVALARA-LAPDPELILL 162
Cdd:PTZ00243  1400 VRQNVdpfleassaevwaALELVGLRERVASESEGIDSRV-LEGGS--------NYSVGQRQLMCMARAlLKKGSGFILM 1470

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1067578656  163 DEPFSALDEQLRRQIREDMIAALRANgkSAVFVSHDREEALQYaDRIAVMKQGRILQTASPHEL 226
Cdd:PTZ00243  1471 DEATANIDPALDRQIQATVMSAFSAY--TVITIAHRLHTVAQY-DKIIVMDHGAVAEMGSPREL 1531
PRK10790 PRK10790
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
7-226 7.91e-13

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;


Pssm-ID: 182733 [Multi-domain]  Cd Length: 592  Bit Score: 69.36  E-value: 7.91e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   7 IGHLSKSFQN-TPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSkntnLPVRERRLGY- 84
Cdd:PRK10790  343 IDNVSFAYRDdNLVLQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPLSS----LSHSVLRQGVa 418

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  85 LVQEGVLFPHLTVYRNIAYglgngkGRTAQERQRIEAmLELTGISELAGRYP-----------HELSGGQQQRVALARAL 153
Cdd:PRK10790  419 MVQQDPVVLADTFLANVTL------GRDISEEQVWQA-LETVQLAELARSLPdglytplgeqgNNLSVGQKQLLALARVL 491

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1067578656 154 APDPELILLDEPFSALDEQLRRQIREdMIAALRANgKSAVFVSHdREEALQYADRIAVMKQGRILQTASPHEL 226
Cdd:PRK10790  492 VQTPQILILDEATANIDSGTEQAIQQ-ALAAVREH-TTLVVIAH-RLSTIVEADTILVLHRGQAVEQGTHQQL 561
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
116-303 8.37e-13

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 68.61  E-value: 8.37e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 116 RQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDEQLRRQIREDMIAALRaNGKSAVFV 195
Cdd:NF000106  122 RARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMVR-DGATVLLT 200

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 196 SHDREEALQYADRIAVMKQGRILQTASPHELYRQ------------PADLDAALfigeGIVFPAALN--ADGTADCRLG- 260
Cdd:NF000106  201 TQYMEEAEQLAHELTVIDRGRVIADGKVDELKTKvggrtlqirpahAAELDRMV----GAIAQAGLDgiAGATADHEDGv 276

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1067578656 261 -RLPV----QSGAPAGTRGTllirpEQFSLHPHSAPAASIHAVVLKTT 303
Cdd:NF000106  277 vNVPIvsdeQLSAVVGMLGE-----RGFTISGHQHPSAQL*EVFLAIT 319
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
 5-199 1.09e-12

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 69.04  E-value: 1.09e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSgKTIfskntnlpvrerRLGY 84
Cdd:PRK10636  313 LKMEKVSAGYGDRIILDSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEIGLA-KGI------------KLGY 379

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  85 LVQEGVLF--------PHLTvyrniayglgngkgRTAQerQRIEAMLE--LTG-------ISELAGRYphelSGGQQQRV 147
Cdd:PRK10636  380 FAQHQLEFlradesplQHLA--------------RLAP--QELEQKLRdyLGGfgfqgdkVTEETRRF----SGGEKARL 439

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1067578656 148 ALARALAPDPELILLDEPFSALDEQLRRQIREDMI---AALrangksaVFVSHDR 199
Cdd:PRK10636  440 VLALIVWQRPNLLLLDEPTNHLDLDMRQALTEALIdfeGAL-------VVVSHDR 487
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
 15-212 3.68e-12

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 67.75  E-value: 3.68e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   15 QNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFsKNTNLPVRERRLGYLVQEGVLFPH 94
Cdd:PTZ00265   396 KDVEIYKDLNFTLTEGKTYAFVGESGCGKSTILKLIERLYDPTEGDIIINDSHNL-KDINLKWWRSKIGVVSQDPLLFSN 474

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   95 lTVYRNIAYGLGNGKGRTAQERQ------------------RIEAMLELTGISE-------------------------- 130
Cdd:PTZ00265   475 -SIKNNIKYSLYSLKDLEALSNYynedgndsqenknkrnscRAKCAGDLNDMSNttdsneliemrknyqtikdsevvdvs 553

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  131 ------------------LAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDEQLRRQIREdMIAALRANGKSA 192
Cdd:PTZ00265   554 kkvlihdfvsalpdkyetLVGSNASKLSGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYLVQK-TINNLKGNENRI 632

                          250       260
                   ....*....|....*....|
gi 1067578656  193 VFVSHDREEALQYADRIAVM 212
Cdd:PTZ00265   633 TIIIAHRLSTIRYANTIFVL 652
PLN03232 PLN03232
ABC transporter C family member; Provisional
 18-226 5.63e-12

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 67.31  E-value: 5.63e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   18 PVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfSKNTNLPVReRRLGYLVQEGVLFPHlTV 97
Cdd:PLN03232  1250 PVLHGLSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVELEKGRIMIDDCDV-AKFGLTDLR-RVLSIIPQSPVLFSG-TV 1326

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   98 YRNI-AYGLGNGKGR-TAQERQRIEAMLELT--GISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDEQ- 172
Cdd:PLN03232  1327 RFNIdPFSEHNDADLwEALERAHIKDVIDRNpfGLDAEVSEGGENFSVGQRQLLSLARALLRRSKILVLDEATASVDVRt 1406

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1067578656  173 ---LRRQIREDMIAAlrangkSAVFVSHdREEALQYADRIAVMKQGRILQTASPHEL 226
Cdd:PLN03232  1407 dslIQRTIREEFKSC------TMLVIAH-RLNTIIDCDKILVLSSGQVLEYDSPQEL 1456
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
29-198 2.02e-11

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 64.83  E-value: 2.02e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  29 PGEILFIIGASGCGKTTLLRCLAG--------FEQPDSGEISL---SGKTIFSKNTNLPVRERRLGYLVQEGVLFPHLTv 97
Cdd:PRK13409   98 EGKVTGILGPNGIGKTTAVKILSGelipnlgdYEEEPSWDEVLkrfRGTELQNYFKKLYNGEIKVVHKPQYVDLIPKVF- 176

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  98 yrniayglgNGKGR----TAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDeql 173
Cdd:PRK13409  177 ---------KGKVRellkKVDERGKLDEVVERLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPTSYLD--- 244

                         170       180
                  ....*....|....*....|....*....
gi 1067578656 174 rrqIREDMIAA--LR--ANGKSAVFVSHD 198
Cdd:PRK13409  245 ---IRQRLNVArlIRelAEGKYVLVVEHD 270
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
 19-172 2.36e-11

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 65.13  E-value: 2.36e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   19 VLNDISLSLDPGEILFIIGASGCGKTTLLRCLAgfEQPDSGEISlSGKTIfsknTNLPVR----ERRLGYLVQEGVLFPH 94
Cdd:TIGR00956  778 ILNNVDGWVKPGTLTALMGASGAGKTTLLNVLA--ERVTTGVIT-GGDRL----VNGRPLdssfQRSIGYVQQQDLHLPT 850

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   95 LTVYRNIAYG--LGNGKGRTAQERQR-IEAMLELTGISELA----GRYPHELSGGQQQRVALARALAPDPELIL-LDEPF 166
Cdd:TIGR00956  851 STVRESLRFSayLRQPKSVSKSEKMEyVEEVIKLLEMESYAdavvGVPGEGLNVEQRKRLTIGVELVAKPKLLLfLDEPT 930


                   ....*.
gi 1067578656  167 SALDEQ 172
Cdd:TIGR00956  931 SGLDSQ 936
GguA NF040905
sugar ABC transporter ATP-binding protein;
19-217 2.83e-11

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 64.43  E-value: 2.83e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  19 VLNDISLSLDPGEILFIIGASGCGKTTLLRCLAG--FEQPDSGEISLSGKTIFSKNTNLPVR-------ERRLGY-LVQE 88
Cdd:NF040905  275 VVDDVSLNVRRGEIVGIAGLMGAGRTELAMSVFGrsYGRNISGTVFKDGKEVDVSTVSDAIDaglayvtEDRKGYgLNLI 354

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  89 GvlfphlTVYRNI-AYGLG----------NGKGRTAQE---RQRIEAmlelTGISELAGRypheLSGGQQQRVALARALA 154
Cdd:NF040905  355 D------DIKRNItLANLGkvsrrgvideNEEIKVAEEyrkKMNIKT----PSVFQKVGN----LSGGNQQKVVLSKWLF 420

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1067578656 155 PDPELILLDEPFSALDEQLRRQIREdMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRI 217
Cdd:NF040905  421 TDPDVLILDEPTRGIDVGAKYEIYT-IINELAAEGKGVIVISSELPELLGMCDRIYVMNEGRI 482
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 29-201 3.42e-11

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 60.85  E-value: 3.42e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   29 PGEILFIIGASGCGKTTLLRCLAGFEQPDsgeislsGKTIFSKNTNlpvrerrlgylvqegvlfphltvyrniayglgng 108
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPP-------GGGVIYIDGE---------------------------------- 39

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  109 kgrtaqerqRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDEQLRRQIREDMIAAL--- 185
Cdd:smart00382  40 ---------DILEEVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLLEELRLlll 110

                          170
                   ....*....|....*...
gi 1067578656  186 --RANGKSAVFVSHDREE 201
Cdd:smart00382 111 lkSEKNLTVILTTNDEKD 128
ABC_UvrA cd03238
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ...
 20-209 3.57e-11

ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213205 [Multi-domain]  Cd Length: 176  Bit Score: 61.18  E-value: 3.57e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  20 LNDISLSLDPGEILFIIGASGCGKTTLlrCLAGFEQpdSGEISL-SGKTIFSKNtnLPVRERRLGYLvqegvlfphltvy 98
Cdd:cd03238    11 LQNLDVSIPLNVLVVVTGVSGSGKSTL--VNEGLYA--SGKARLiSFLPKFSRN--KLIFIDQLQFL------------- 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  99 rnIAYGLGngkgrtaqerqrieaMLELtgiselaGRYPHELSGGQQQRVALARALA--PDPELILLDEPFSALDEQLRRQ 176
Cdd:cd03238    72 --IDVGLG---------------YLTL-------GQKLSTLSGGELQRVKLASELFsePPGTLFILDEPSTGLHQQDINQ 127

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1067578656 177 IREdMIAALRANGKSAVFVSHDrEEALQYADRI 209
Cdd:cd03238   128 LLE-VIKGLIDLGNTVILIEHN-LDVLSSADWI 158
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 29-198 6.79e-11

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 63.26  E-value: 6.79e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  29 PGEILFIIGASGCGKTTLLRCLAGFEQPDSGEIS-----------LSGKTIFSkntnlpvrerrlgYL--VQEGvlfpHL 95
Cdd:COG1245    98 KGKVTGILGPNGIGKSTALKILSGELKPNLGDYDeepswdevlkrFRGTELQD-------------YFkkLANG----EI 160

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  96 TVYRNIAY-----GLGNGKGRT----AQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPF 166
Cdd:COG1245   161 KVAHKPQYvdlipKVFKGTVREllekVDERGKLDELAEKLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPS 240

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1067578656 167 SALD--EQLR--RQIREdmiaaLRANGKSAVFVSHD 198
Cdd:COG1245   241 SYLDiyQRLNvaRLIRE-----LAEEGKYVLVVEHD 271
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
 20-200 1.50e-10

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 62.28  E-value: 1.50e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  20 LNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSgktifsknTNLPVrerrlGYLVQ-EGVLFPHLTVY 98
Cdd:PRK11147  335 VKDFSAQVQRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRIHCG--------TKLEV-----AYFDQhRAELDPEKTVM 401

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  99 RNIAYG----LGNGKGRtaqerqRIEAMLELTGISELAGRYP-HELSGGQQQRVALARALAPDPELILLDEPFSALD-EQ 172
Cdd:PRK11147  402 DNLAEGkqevMVNGRPR------HVLGYLQDFLFHPKRAMTPvKALSGGERNRLLLARLFLKPSNLLILDEPTNDLDvET 475

                         170       180
                  ....*....|....*....|....*...
gi 1067578656 173 LrrQIREDMIAALRAngkSAVFVSHDRE 200
Cdd:PRK11147  476 L--ELLEELLDSYQG---TVLLVSHDRQ 498
ABC_RNaseL_inhibitor cd03222
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ...
 30-211 2.31e-10

ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213189 [Multi-domain]  Cd Length: 177  Bit Score: 59.12  E-value: 2.31e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  30 GEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNtnlpvrerrlgylvqegvlfphltvyrniayglgngk 109
Cdd:cd03222    25 GEVIGIVGPNGTGKTTAVKILAGQLIPNGDNDEWDGITPVYKP------------------------------------- 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 110 grtaqerQRIEamleltgiselagrypheLSGGQQQRVALARALAPDPELILLDEPFSALDEQLRRQIREDMIAALRANG 189
Cdd:cd03222    68 -------QYID------------------LSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNAARAIRRLSEEGK 122

                         170       180
                  ....*....|....*....|..
gi 1067578656 190 KSAVFVSHDREEALQYADRIAV 211
Cdd:cd03222   123 KTALVVEHDLAVLDYLSDRIHV 144
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
 36-199 2.89e-10

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 61.45  E-value: 2.89e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  36 IGASGCGKTTLLRCLAGFEQPDSGEISLSGKTifskntnlpvrerRLGYLVQEGVLFPHLTVYRNIAYG---LGNGKgrt 112
Cdd:PRK15064   33 IGANGCGKSTFMKILGGDLEPSAGNVSLDPNE-------------RLGKLRQDQFAFEEFTVLDTVIMGhteLWEVK--- 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 113 aQERQRIEAMLELT---GI--SELAGRYP------------------------H-----ELSGGQQQRVALARALAPDPE 158
Cdd:PRK15064   97 -QERDRIYALPEMSeedGMkvADLEVKFAemdgytaearagelllgvgipeeqHyglmsEVAPGWKLRVLLAQALFSNPD 175

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1067578656 159 LILLDEPFSALDEQlrrQIR--EDMiaaLRANGKSAVFVSHDR 199
Cdd:PRK15064  176 ILLLDEPTNNLDIN---TIRwlEDV---LNERNSTMIIISHDR 212
PLN03073 PLN03073
ABC transporter F family; Provisional
 18-217 4.67e-10

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 61.03  E-value: 4.67e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  18 PVL-NDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKT---IFSKN--TNLPVRERRLGYLVQegvL 91
Cdd:PLN03073  522 PLLfKNLNFGIDLDSRIAMVGPNGIGKSTILKLISGELQPSSGTVFRSAKVrmaVFSQHhvDGLDLSSNPLLYMMR---C 598

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  92 FPHLTvyrniayglgngkgrtaqeRQRIEAMLELTGIS-ELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALD 170
Cdd:PLN03073  599 FPGVP-------------------EQKLRAHLGSFGVTgNLALQPMYTLSGGQKSRVAFAKITFKKPHILLLDEPSNHLD 659

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1067578656 171 eqlrRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRI 217
Cdd:PLN03073  660 ----LDAVEALIQGLVLFQGGVLMVSHDEHLISGSVDELWVVSEGKV 702
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
 11-256 1.17e-09

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 59.74  E-value: 1.17e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   11 SKSFQntpVLNDISLSLDPGEILFIIGASGCGKTTLLRCLA----GFEQPDSGEISLSGktiFSKNTNLPVRERRLGYLV 86
Cdd:TIGR00956   71 TKTFD---ILKPMDGLIKPGELTVVLGRPGSGCSTLLKTIAsntdGFHIGVEGVITYDG---ITPEEIKKHYRGDVVYNA 144

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   87 QEGVLFPHLTVYRNIAY-----GLGN-GKGRTAQERQRIEAMLELT--GIS-----ELAGRYPHELSGGQQQRVALARAL 153
Cdd:TIGR00956  145 ETDVHFPHLTVGETLDFaarckTPQNrPDGVSREEYAKHIADVYMAtyGLShtrntKVGNDFVRGVSGGERKRVSIAEAS 224

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  154 APDPELILLDEPFSALDEQLRRQIredmIAALRANG---KSAVFVS--HDREEALQYADRIAVMKQGRIlqtaspheLYR 228
Cdd:TIGR00956  225 LGGAKIQCWDNATRGLDSATALEF----IRALKTSAnilDTTPLVAiyQCSQDAYELFDKVIVLYEGYQ--------IYF 292

                          250       260
                   ....*....|....*....|....*...
gi 1067578656  229 QPADLDAALFIGEGIVFPaalNADGTAD 256
Cdd:TIGR00956  293 GPADKAKQYFEKMGFKCP---DRQTTAD 317
ABC_RNaseL_inhibitor_domain1 cd03236
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 29-198 1.41e-09

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213203 [Multi-domain]  Cd Length: 255  Bit Score: 57.76  E-value: 1.41e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  29 PGEILFIIGASGCGKTTLLRCLAGFEQPDSGEislsgktiFSKNTNLP--VRERR-------LGYLVQEGVLFPHLTVYR 99
Cdd:cd03236    25 EGQVLGLVGPNGIGKSTALKILAGKLKPNLGK--------FDDPPDWDeiLDEFRgselqnyFTKLLEGDVKVIVKPQYV 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 100 NIAYGLGNGKGR----TAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDEQLR- 174
Cdd:cd03236    97 DLIPKAVKGKVGellkKKDERGKLDELVDQLELRHVLDRNIDQLSGGELQRVAIAAALARDADFYFFDEPSSYLDIKQRl 176

                         170       180
                  ....*....|....*....|....*..
gi 1067578656 175 ---RQIREdmiaaLRANGKSAVFVSHD 198
Cdd:cd03236   177 naaRLIRE-----LAEDDNYVLVVEHD 198
tagH PRK13545
teichoic acids export protein ATP-binding subunit; Provisional
 20-197 1.43e-09

teichoic acids export protein ATP-binding subunit; Provisional


Pssm-ID: 184130 [Multi-domain]  Cd Length: 549  Bit Score: 59.13  E-value: 1.43e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  20 LNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFskntnlpvrerrlgYLVQEGvLFPHLTVYR 99
Cdd:PRK13545   40 LNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTVDIKGSAAL--------------IAISSG-LNGQLTGIE 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 100 NIAYGlGNGKGRTAQERQRI-EAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALDEQLRRQIR 178
Cdd:PRK13545  105 NIELK-GLMMGLTKEKIKEIiPEIIEFADIGKFIYQPVKTYSSGMKSRLGFAISVHINPDILVIDEALSVGDQTFTKKCL 183

                         170
                  ....*....|....*....
gi 1067578656 179 EDMiAALRANGKSAVFVSH 197
Cdd:PRK13545  184 DKM-NEFKEQGKTIFFISH 201
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
 19-229 1.56e-09

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 59.57  E-value: 1.56e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   19 VLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfsKNTNLPVRERRLGYLVQEGVLFPHlTVY 98
Cdd:TIGR00957 1301 VLRHINVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGLNI--AKIGLHDLRFKITIIPQDPVLFSG-SLR 1377

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   99 RNIayglgNGKGRTAQERqrIEAMLEL----TGISELAGRYPHE-------LSGGQQQRVALARALAPDPELILLDEPFS 167
Cdd:TIGR00957 1378 MNL-----DPFSQYSDEE--VWWALELahlkTFVSALPDKLDHEcaeggenLSVGQRQLVCLARALLRKTKILVLDEATA 1450

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1067578656  168 ALDEQLRRQIRedmiAALRANGK--SAVFVSHDREEALQYAdRIAVMKQGRILQTASPHELYRQ 229
Cdd:TIGR00957 1451 AVDLETDNLIQ----STIRTQFEdcTVLTIAHRLNTIMDYT-RVIVLDKGEVAEFGAPSNLLQQ 1509
sufC PRK09580
cysteine desulfurase ATPase component; Reviewed
 5-220 1.68e-09

cysteine desulfurase ATPase component; Reviewed


Pssm-ID: 181965 [Multi-domain]  Cd Length: 248  Bit Score: 57.49  E-value: 1.68e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFE--QPDSGEISLSGKTIFSKNTnlpvrERRL 82
Cdd:PRK09580    2 LSIKDLHVSVEDKAILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAGREdyEVTGGTVEFKGKDLLELSP-----EDRA 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  83 GYLV----QEGVLFPHLTVYRNIAYGLGNGKGRTAQE-------RQRIEAMLELTGISE-LAGRYPHE-LSGGQQQRVAL 149
Cdd:PRK09580   77 GEGIfmafQYPVEIPGVSNQFFLQTALNAVRSYRGQEpldrfdfQDLMEEKIALLKMPEdLLTRSVNVgFSGGEKKRNDI 156

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1067578656 150 ARALAPDPELILLDEPFSALD-EQLRrqIREDMIAALRANGKSAVFVSHdREEALQY--ADRIAVMKQGRILQT 220
Cdd:PRK09580  157 LQMAVLEPELCILDESDSGLDiDALK--IVADGVNSLRDGKRSFIIVTH-YQRILDYikPDYVHVLYQGRIVKS 227
ABCC_CFTR2 cd03289
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ...
 17-237 8.90e-09

ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213256 [Multi-domain]  Cd Length: 275  Bit Score: 55.63  E-value: 8.90e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  17 TPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDsGEISLSGktiFSKNTnLPVRERR--LGYLVQEGVLFPH 94
Cdd:cd03289    17 NAVLENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLNTE-GDIQIDG---VSWNS-VPLQKWRkaFGVIPQKVFIFSG 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  95 lTVYRNI-AYGLGNGkgrtaqerQRIEAMLELTGISELAGRYPHE-----------LSGGQQQRVALARALAPDPELILL 162
Cdd:cd03289    92 -TFRKNLdPYGKWSD--------EEIWKVAEEVGLKSVIEQFPGQldfvlvdggcvLSHGHKQLMCLARSVLSKAKILLL 162

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1067578656 163 DEPFSALDEQLRRQIREDMIAALranGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPADLDAAL 237
Cdd:cd03289   163 DEPSAHLDPITYQVIRKTLKQAF---ADCTVILSEHRIEAMLECQRFLVIEENKVRQYDSIQKLLNEKSHFKQAI 234
PLN03140 PLN03140
ABC transporter G family member; Provisional
 19-170 1.50e-08

ABC transporter G family member; Provisional


Pssm-ID: 215599 [Multi-domain]  Cd Length: 1470  Bit Score: 56.39  E-value: 1.50e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   19 VLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPD--SGEISLSGktiFSKNTNLPVRERrlGYLVQEGVLFPHLT 96
Cdd:PLN03140   895 LLREVTGAFRPGVLTALMGVSGAGKTTLMDVLAGRKTGGyiEGDIRISG---FPKKQETFARIS--GYCEQNDIHSPQVT 969

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   97 VYRNIAYG--LGNGKGRTAQERQR-IEAMLEL----------TGISELAGrypheLSGGQQQRVALARALAPDPELILLD 163
Cdd:PLN03140   970 VRESLIYSafLRLPKEVSKEEKMMfVDEVMELveldnlkdaiVGLPGVTG-----LSTEQRKRLTIAVELVANPSIIFMD 1044


                   ....*..
gi 1067578656  164 EPFSALD 170
Cdd:PLN03140  1045 EPTSGLD 1051
PRK13546 PRK13546
teichoic acids export ABC transporter ATP-binding subunit TagH;
4-217 1.84e-08

teichoic acids export ABC transporter ATP-binding subunit TagH;


Pssm-ID: 184131 [Multi-domain]  Cd Length: 264  Bit Score: 54.82  E-value: 1.84e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   4 ALHIGHLSKSFQntpVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGK-TIFSKNTNLPVRerrl 82
Cdd:PRK13546   27 ALIPKHKNKTFF---ALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVDRNGEvSVIAISAGLSGQ---- 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  83 gylvqegvlfphLTVYRNIAYG---LGngkgrtaQERQRIEAML-ELTGISELaGRYPHE----LSGGQQQRVALARALA 154
Cdd:PRK13546  100 ------------LTGIENIEFKmlcMG-------FKRKEIKAMTpKIIEFSEL-GEFIYQpvkkYSSGMRAKLGFSINIT 159

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1067578656 155 PDPELILLDEPFSALDeQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRI 217
Cdd:PRK13546  160 VNPDILVIDEALSVGD-QTFAQKCLDKIYEFKEQNKTIFFVSHNLGQVRQFCTKIAWIEGGKL 221
ABC_Rad50 cd03240
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ...
 28-209 2.54e-08

ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.


Pssm-ID: 213207 [Multi-domain]  Cd Length: 204  Bit Score: 53.38  E-value: 2.54e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  28 DPGEILF------IIGASGCGKTTLLRCL-------------AGFEQPD---SGEISLSGKTIFSKNTNLPVRERRlgyl 85
Cdd:cd03240    14 ERSEIEFfspltlIVGQNGAGKTTIIEALkyaltgelppnskGGAHDPKlirEGEVRAQVKLAFENANGKKYTITR---- 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  86 vqegvlfpHLTVYRNIAYglgngkgrTAQERQRIEAMLELtgiselaGRypheLSGGQQQ------RVALARALAPDPEL 159
Cdd:cd03240    90 --------SLAILENVIF--------CHQGESNWPLLDMR-------GR----CSGGEKVlasliiRLALAETFGSNCGI 142

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1067578656 160 ILLDEPFSALD-EQLRRQIREDMIAALRANGKSAVFVSHDrEEALQYADRI 209
Cdd:cd03240   143 LALDEPTTNLDeENIEESLAEIIEERKSQKNFQLIVITHD-EELVDAADHI 192
ABC_Class2 cd03227
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ...
 4-213 3.76e-08

ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.


Pssm-ID: 213194 [Multi-domain]  Cd Length: 162  Bit Score: 52.36  E-value: 3.76e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   4 ALHIGHlsksFQNTPVLNDISLSldPGEILFIIGASGCGKTTLLRCLagfeqpdsgeislsgktifskntnlpvrerrlG 83
Cdd:cd03227     1 KIVLGR----FPSYFVPNDVTFG--EGSLTIITGPNGSGKSTILDAI--------------------------------G 42

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  84 YLVqeGVLFPHLTVYRNIAYGLgngkgrtaqerqrIEAMLELTGISELagrypHELSGGQQQRVALARALA-----PDPe 158
Cdd:cd03227    43 LAL--GGAQSATRRRSGVKAGC-------------IVAAVSAELIFTR-----LQLSGGEKELSALALILAlaslkPRP- 101

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1067578656 159 LILLDEPFSALDEQlRRQIREDMIAALRANGKSAVFVSHDrEEALQYADRIAVMK 213
Cdd:cd03227   102 LYILDEIDRGLDPR-DGQALAEAILEHLVKGAQVIVITHL-PELAELADKLIHIK 154
PLN03130 PLN03130
ABC transporter C family member; Provisional
 18-226 6.80e-08

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 54.36  E-value: 6.80e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   18 PVLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIfSKNTNLPVReRRLGYLVQEGVLFP---- 93
Cdd:PLN03130  1253 PVLHGLSFEISPSEKVGIVGRTGAGKSSMLNALFRIVELERGRILIDGCDI-SKFGLMDLR-KVLGIIPQAPVLFSgtvr 1330

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   94 ---------------------HLT-VYRNiayglgNGKGRTAQerqrieamleltgISElAGrypHELSGGQQQRVALAR 151
Cdd:PLN03130  1331 fnldpfnehndadlwesleraHLKdVIRR------NSLGLDAE-------------VSE-AG---ENFSVGQRQLLSLAR 1387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  152 ALAPDPELILLDEPFSALDEQ----LRRQIRED------MIAALRANgksavfvshdreeALQYADRIAVMKQGRILQTA 221
Cdd:PLN03130  1388 ALLRRSKILVLDEATAAVDVRtdalIQKTIREEfksctmLIIAHRLN-------------TIIDCDRILVLDAGRVVEFD 1454


                   ....*
gi 1067578656  222 SPHEL 226
Cdd:PLN03130  1455 TPENL 1459
ABCC_SUR2 cd03288
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ...
 5-237 6.10e-07

ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213255 [Multi-domain]  Cd Length: 257  Bit Score: 49.91  E-value: 6.10e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQNT--PVLNDISLSLDPGEILFIIGASGCGKTTLlrCLAGFEQPD--SGEISLSGKTIfsknTNLPVR-- 78
Cdd:cd03288    20 IKIHDLCVRYENNlkPVLKHVKAYIKPGQKVGICGRTGSGKSSL--SLAFFRMVDifDGKIVIDGIDI----SKLPLHtl 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  79 ERRLGYLVQEGVLFPHltvyrNIAYGLGNGKGRTaqeRQRIEAMLELTGISELAGRYPHEL-----------SGGQQQRV 147
Cdd:cd03288    94 RSRLSIILQDPILFSG-----SIRFNLDPECKCT---DDRLWEALEIAQLKNMVKSLPGGLdavvteggenfSVGQRQLF 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 148 ALARALAPDPELILLDEPFSALDEQLRRQIREDMIAALRanGKSAVFVSHdREEALQYADRIAVMKQGRILQTASPHELY 227
Cdd:cd03288   166 CLARAFVRKSSILIMDEATASIDMATENILQKVVMTAFA--DRTVVTIAH-RVSTILDADLVLVLSRGILVECDTPENLL 242

                         250
                  ....*....|
gi 1067578656 228 RQPADLDAAL 237
Cdd:cd03288   243 AQEDGVFASL 252
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
 19-237 6.41e-07

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 51.45  E-value: 6.41e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   19 VLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDsGEISLSGktIFSKNTNLPVRERRLGYLVQEGVLFPHlTVY 98
Cdd:TIGR01271 1234 VLQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRLLSTE-GEIQIDG--VSWNSVTLQTWRKAFGVIPQKVFIFSG-TFR 1309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   99 RNIayglgngkgrTAQER---QRIEAMLELTGISELAGRYPHE-----------LSGGQQQRVALARALAPDPELILLDE 164
Cdd:TIGR01271 1310 KNL----------DPYEQwsdEEIWKVAEEVGLKSVIEQFPDKldfvlvdggyvLSNGHKQLMCLARSILSKAKILLLDE 1379

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1067578656  165 PFSALDEQLRRQIREDMIAALranGKSAVFVSHDREEALQYADRIAVMKQGRILQTASPHELYRQPADLDAAL 237
Cdd:TIGR01271 1380 PSAHLDPVTLQIIRKTLKQSF---SNCTVILSEHRVEALLECQQFLVIEGSSVKQYDSIQKLLNETSLFKQAM 1449
3a01203 TIGR00954
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ...
 14-169 1.17e-06

Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 273360 [Multi-domain]  Cd Length: 659  Bit Score: 50.13  E-value: 1.17e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  14 FQNTPV--------LNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEIslsgkTIFSKNTNLPVRER---RL 82
Cdd:TIGR00954 454 FENIPLvtpngdvlIESLSFEVPSGNNLLICGPNGCGKSSLFRILGELWPVYGGRL-----TKPAKGKLFYVPQRpymTL 528

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  83 GYLvQEGVLFPHlTVYRNIAYGLGNgkgrtaqerQRIEAMLELTGISELAGR---------YPHELSGGQQQRVALARAL 153
Cdd:TIGR00954 529 GTL-RDQIIYPD-SSEDMKRRGLSD---------KDLEQILDNVQLTHILEReggwsavqdWMDVLSGGEKQRIAMARLF 597

                         170
                  ....*....|....*.
gi 1067578656 154 APDPELILLDEPFSAL 169
Cdd:TIGR00954 598 YHKPQFAILDECTSAV 613
PLN03073 PLN03073
ABC transporter F family; Provisional
 5-170 1.28e-06

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 50.24  E-value: 1.28e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656   5 LHIGHLSKSFQNTPVLNDISLSLDPGEILFIIGASGCGKTTLLRCLA--------------GFEQPDSGEISLSGKTIFS 70
Cdd:PLN03073  178 IHMENFSISVGGRDLIVDASVTLAFGRHYGLVGRNGTGKTTFLRYMAmhaidgipkncqilHVEQEVVGDDTTALQCVLN 257

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  71 KN---TNLPVRERRLgYLVQEGVLFPHLTVYRNIAYGLGNGKGRTAQERQRIEAMLE--------------LTGIS---E 130
Cdd:PLN03073  258 TDierTQLLEEEAQL-VAQQRELEFETETGKGKGANKDGVDKDAVSQRLEEIYKRLElidaytaearaasiLAGLSftpE 336

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1067578656 131 LAGRYPHELSGGQQQRVALARALAPDPELILLDEPFSALD 170
Cdd:PLN03073  337 MQVKATKTFSGGWRMRIALARALFIEPDLLLLDEPTNHLD 376
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
 19-214 3.99e-06

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 48.63  E-value: 3.99e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  19 VLNDISLSLDPGEILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFS-KNTNLPVRER-RLGYLVQEGVLFPHLT 96
Cdd:PRK10636   16 LLDNATATINPGQKVGLVGKNGCGKSTLLALLKNEISADGGSYTFPGNWQLAwVNQETPALPQpALEYVIDGDREYRQLE 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  97 VYRNIA--------YGLGNGKGRTAQE---RQRIEAMLELTGISELAGRYP-HELSGGQQQRVALARALAPDPELILLDE 164
Cdd:PRK10636   96 AQLHDAnerndghaIATIHGKLDAIDAwtiRSRAASLLHGLGFSNEQLERPvSDFSGGWRMRLNLAQALICRSDLLLLDE 175

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1067578656 165 PFSALDeqlrrqirEDMIAALRANGKS----AVFVSHDREEALQYADRIAVMKQ 214
Cdd:PRK10636  176 PTNHLD--------LDAVIWLEKWLKSyqgtLILISHDRDFLDPIVDKIIHIEQ 221
ABC_UvrA_I cd03270
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair ...
 20-209 1.14e-05

ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213237 [Multi-domain]  Cd Length: 226  Bit Score: 45.71  E-value: 1.14e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  20 LNDISLSLDPGEILFIIGASGCGKTTLL---------------------RCLAGFEQPD-------SGEISLSGKTIfSK 71
Cdd:cd03270    11 LKNVDVDIPRNKLVVITGVSGSGKSSLAfdtiyaegqrryveslsayarQFLGQMDKPDvdsieglSPAIAIDQKTT-SR 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  72 NT-------------------NLPVRERrLGYLVQEGVlfPHLTVYRNIAyglgngkgrtaqerqrieamleltgisela 132
Cdd:cd03270    90 NPrstvgtvteiydylrllfaRVGIRER-LGFLVDVGL--GYLTLSRSAP------------------------------ 136

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1067578656 133 gryphELSGGQQQRVALARALAPDPELIL--LDEPFSALDEQLRRQIREdMIAALRANGKSAVFVSHDrEEALQYADRI 209
Cdd:cd03270   137 -----TLSGGEAQRIRLATQIGSGLTGVLyvLDEPSIGLHPRDNDRLIE-TLKRLRDLGNTVLVVEHD-EDTIRAADHV 208
SbcC_Walker_B pfam13558
SbcC/RAD50-like, Walker B motif; This entry represents the Walker B domain of RAD50 from ...
 138-187 1.64e-05

SbcC/RAD50-like, Walker B motif; This entry represents the Walker B domain of RAD50 from eukaryotes and the prokaryotic homolog SbcCD complex subunit C. RAD50-ATPase forms a complex with Mre11-nuclease that detects and processes diverse and obstructed DNA ends. This domain is separated of the Walker A domain by a long coiled-coil domain and forms the nucleotide-binding domain (NBD) when the coiled coils fold back on themselves and bring together Walker A and B domains. Two RAD50-NBDs forms heterotetramers with a Mre11 nuclease dimer that assemble as catalytic head module that binds and cleaves DNA in an ATP-dependent reaction. Through secondary structural analysis, it has been suggested that there is a wide structural conservation in the Rad50/SMC protein family as seen in structural similarities between RAD50's hook and ABC-ATPase MukB's elbow region.


Pssm-ID: 463921 [Multi-domain]  Cd Length: 90  Bit Score: 42.99  E-value: 1.64e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1067578656 138 ELSGGQQQR---VALARALA----------PDPELILLDEPFSALDEQLRRQiredMIAALRA 187
Cdd:pfam13558  32 GLSGGEKQLlayLPLAAALAaqygsaegrpPAPRLVFLDEAFAKLDEENIRT----ALELLRA 90
PRK00635 PRK00635
excinuclease ABC subunit A; Provisional
 116-235 2.25e-05

excinuclease ABC subunit A; Provisional


Pssm-ID: 234806 [Multi-domain]  Cd Length: 1809  Bit Score: 46.36  E-value: 2.25e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  116 RQRIEAMLELtGISELA-GRYPHELSGGQQQRVALARALApdPELI----LLDEPFSALDEQLRRQIReDMIAALRANGK 190
Cdd:PRK00635   454 KSRLSILIDL-GLPYLTpERALATLSGGEQERTALAKHLG--AELIgityILDEPSIGLHPQDTHKLI-NVIKKLRDQGN 529

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1067578656  191 SAVFVSHDrEEALQYADRI------AVMKQGRILQTASPHELYRQPADLDA 235
Cdd:PRK00635   530 TVLLVEHD-EQMISLADRIidigpgAGIFGGEVLFNGSPREFLAKSDSLTA 579
ABC_sbcCD cd03279
ATP-binding cassette domain of sbcCD; SbcCD and other Mre11/Rad50 (MR) complexes are ...
 26-213 3.65e-05

ATP-binding cassette domain of sbcCD; SbcCD and other Mre11/Rad50 (MR) complexes are implicated in the metabolism of DNA ends. They cleave ends sealed by hairpin structures and are thought to play a role in removing protein bound to DNA termini.


Pssm-ID: 213246 [Multi-domain]  Cd Length: 213  Bit Score: 44.18  E-value: 3.65e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  26 SLDPGEILFIIGASGCGKTTLLrclagfeqpDSGEISLSGKTIFSKNTNlpvrerRLGYLVQEGVLFPHLTVY---RNIA 102
Cdd:cd03279    24 GLDNNGLFLICGPTGAGKSTIL---------DAITYALYGKTPRYGRQE------NLRSVFAPGEDTAEVSFTfqlGGKK 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 103 YGLGNGKGRTAQERQRIeAMLELTGISELAGRYPHELSGGQQQRVALARALAPDP----------ELILLDEPFSALDEQ 172
Cdd:cd03279    89 YRVERSRGLDYDQFTRI-VLLPQGEFDRFLARPVSTLSGGETFLASLSLALALSEvlqnrggarlEALFIDEGFGTLDPE 167

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1067578656 173 LRRQIrEDMIAALRANGKSAVFVSHDREEALQYADRIAVMK 213
Cdd:cd03279   168 ALEAV-ATALELIRTENRMVGVISHVEELKERIPQRLEVIK 207
SbcC COG0419
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];
12-198 4.80e-05

DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];


Pssm-ID: 440188 [Multi-domain]  Cd Length: 204  Bit Score: 43.85  E-value: 4.80e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  12 KSFQNTPVLNdislsLDPGEILfIIGASGCGKTTLLR--CLAGFEQPDSG-------------------EISLSGKTI-- 68
Cdd:COG0419    11 RSYRDTETID-----FDDGLNL-IVGPNGAGKSTILEaiRYALYGKARSRsklrsdlinvgseeasvelEFEHGGKRYri 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  69 ------FSKNTNLPVRERR--LGYLVQegvlfphLTVYRNIAYGLGNGKGRTAQERQRIEAMLELTG--ISELAGRYP-H 137
Cdd:COG0419    85 errqgeFAEFLEAKPSERKeaLKRLLG-------LEIYEELKERLKELEEALESALEELAELQKLKQeiLAQLSGLDPiE 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1067578656 138 ELSGGQQQRVALARALApdpelILLDepFSALDEQLRRQiredMIAALRangkSAVFVSHD 198
Cdd:COG0419   158 TLSGGERLRLALADLLS-----LILD--FGSLDEERLER----LLDALE----ELAIITHV 203
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
139-209 3.43e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 42.74  E-value: 3.43e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 139 LSGGQqqRVALARA--------LAPDPELILLDEPFSALDEQLRRQIREDMIAALRangK--SAVFVSHDrEEALQYADR 208
Cdd:PRK03918  789 LSGGE--RIALGLAfrlalslyLAGNIPLLILDEPTPFLDEERRRKLVDIMERYLR---KipQVIIVSHD-EELKDAADY 862


                  .
gi 1067578656 209 I 209
Cdd:PRK03918  863 V 863
uvra TIGR00630
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ...
 139-241 9.51e-04

excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273184 [Multi-domain]  Cd Length: 925  Bit Score: 41.15  E-value: 9.51e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 139 LSGGQQQRVALARALApdPELI----LLDEPFSALDEQLRRQIREDMIaALRANGKSAVFVSHDrEEALQYADRI----- 209
Cdd:TIGR00630 489 LSGGEAQRIRLATQIG--SGLTgvlyVLDEPSIGLHQRDNRRLINTLK-RLRDLGNTLIVVEHD-EDTIRAADYVidigp 564

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1067578656 210 -AVMKQGRILQTASPHELYRQPADLDAALFIGE 241
Cdd:TIGR00630 565 gAGEHGGEVVASGTPEEILANPDSLTGQYLSGR 597
AAA_21 pfam13304
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being ...
 32-106 1.86e-03

AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.


Pssm-ID: 433102 [Multi-domain]  Cd Length: 303  Bit Score: 39.68  E-value: 1.86e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1067578656  32 ILFIIGASGCGKTTLLRCLAGFEQPDSGEISLSGKTIFSKNTNLPVRERRLGYLVQEGVLFPHLTVYRNIAYGLG 106
Cdd:pfam13304   1 INVLIGPNGSGKSNLLEALRFLADFDALVIGLTDERSRNGGIGGIPSLLNGIDPKEPIEFEISEFLEDGVRYRYG 75
PRK01156 PRK01156
chromosome segregation protein; Provisional
 139-200 2.65e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 39.88  E-value: 2.65e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656 139 LSGGQQQ------RVALARALAPDPELILLDEPFSALDEQLRRQIREDMIAALRANG--KSAVFVSHDRE 200
Cdd:PRK01156  802 LSGGEKTavafalRVAVAQFLNNDKSLLIMDEPTAFLDEDRRTNLKDIIEYSLKDSSdiPQVIMISHHRE 871
ABC_SMC3_euk cd03272
ATP-binding cassette domain of eukaryotic SMC3 proteins; The structural maintenance of ...
 138-209 6.04e-03

ATP-binding cassette domain of eukaryotic SMC3 proteins; The structural maintenance of chromosomes (SMC) proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18).


Pssm-ID: 213239 [Multi-domain]  Cd Length: 243  Bit Score: 37.62  E-value: 6.04e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1067578656 138 ELSGGQQQRVALARALA-----PDPeLILLDEPFSALDEQLRRQIrEDMIAALranGKSAVFVSHD-REEALQYADRI 209
Cdd:cd03272   158 QLSGGQKSLVALALIFAiqkcdPAP-FYLFDEIDAALDAQYRTAV-ANMIKEL---SDGAQFITTTfRPELLEVADKF 230
EutP COG4917
Ethanolamine utilization protein EutP, contains a P-loop NTPase domain [Amino acid transport ...
 33-56 8.30e-03

Ethanolamine utilization protein EutP, contains a P-loop NTPase domain [Amino acid transport and metabolism];


Pssm-ID: 443945 [Multi-domain]  Cd Length: 145  Bit Score: 36.32  E-value: 8.30e-03
                          10        20
                  ....*....|....*....|....
gi 1067578656  33 LFIIGASGCGKTTLLRCLAGFEQP 56
Cdd:COG4917     4 IMLIGRSGAGKTTLTQALNGEELE 27
PRK00635 PRK00635
excinuclease ABC subunit A; Provisional
 139-227 8.57e-03

excinuclease ABC subunit A; Provisional


Pssm-ID: 234806 [Multi-domain]  Cd Length: 1809  Bit Score: 38.27  E-value: 8.57e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067578656  139 LSGGQQQRVALARAL--AP-DPELILLDEPFSALDEQLRRQIREdMIAALRANGKSAVFVSHDrEEALQYADRIAVM--- 212
Cdd:PRK00635  1700 LSLSEKIAIKIAKFLylPPkHPTLFLLDEIATSLDNQQKSALLV-QLRTLVSLGHSVIYIDHD-PALLKQADYLIEMgpg 1777

                           90
                   ....*....|....*...
gi 1067578656  213 --KQ-GRILQTASPHELY 227
Cdd:PRK00635  1778 sgKTgGKILFSGPPKDIS 1795
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
 25-51 9.47e-03

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 36.36  E-value: 9.47e-03
                          10        20
                  ....*....|....*....|....*..
gi 1067578656  25 LSLDPGEILFIIGASGCGKTTLLRCLA 51
Cdd:cd00009    14 LELPPPKNLLLYGPPGTGKTTLARAIA 40
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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