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Conserved domains on  [gi|1447253739|gb|REI87579|]
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phenolic acid decarboxylase [Klebsiella variicola]

Protein Classification

phenolic acid decarboxylase( domain architecture ID 10790237)

phenolic acid decarboxylase catalyzes the decarboxylation and detoxification of phenolic derivatives, including ferulic, p-coumaric and caffeic acids

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PadC COG3479
Phenolic acid decarboxylase [Secondary metabolites biosynthesis, transport and catabolism];
1-167 9.99e-126

Phenolic acid decarboxylase [Secondary metabolites biosynthesis, transport and catabolism];


:

Pssm-ID: 442702  Cd Length: 168  Bit Score: 349.68  E-value: 9.99e-126
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447253739   1 MSTFDKHDLSGFIGKHLVYTYDNGWNYEIYVKNGHTLDYRIHSGIVGNRWVKDQEAYIVRVGESIYKISWTEPTGTDVSL 80
Cdd:COG3479     1 MPTFPQHDLSGFVGKHFIYTYDNGWEYEIYVKNAHTIDYRIHSGMVGGRWVKDQRVDIVRLGEGIYKVSWTEPTGTDVSL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447253739  81 IVNLGDKLFHGTIFFPRWIMNNPEKTVCFQNDHIPLMNSYRDAGPAYPTEVIDEFATITFIRDCGADNDEVINCPASELP 160
Cdd:COG3479    81 DFNLNDRVLHGTIFFPRWVVDHPEKTVCFQNDHLDLMREYRDAGPTYPTEVIDEFATITFIEDCGADNEDVISCAPSELP 160

                  ....*..
gi 1447253739 161 ADFPANL 167
Cdd:COG3479   161 AGYPDRL 167
 
Name Accession Description Interval E-value
PadC COG3479
Phenolic acid decarboxylase [Secondary metabolites biosynthesis, transport and catabolism];
1-167 9.99e-126

Phenolic acid decarboxylase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 442702  Cd Length: 168  Bit Score: 349.68  E-value: 9.99e-126
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447253739   1 MSTFDKHDLSGFIGKHLVYTYDNGWNYEIYVKNGHTLDYRIHSGIVGNRWVKDQEAYIVRVGESIYKISWTEPTGTDVSL 80
Cdd:COG3479     1 MPTFPQHDLSGFVGKHFIYTYDNGWEYEIYVKNAHTIDYRIHSGMVGGRWVKDQRVDIVRLGEGIYKVSWTEPTGTDVSL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447253739  81 IVNLGDKLFHGTIFFPRWIMNNPEKTVCFQNDHIPLMNSYRDAGPAYPTEVIDEFATITFIRDCGADNDEVINCPASELP 160
Cdd:COG3479    81 DFNLNDRVLHGTIFFPRWVVDHPEKTVCFQNDHLDLMREYRDAGPTYPTEVIDEFATITFIEDCGADNEDVISCAPSELP 160

                  ....*..
gi 1447253739 161 ADFPANL 167
Cdd:COG3479   161 AGYPDRL 167
PA_decarbox pfam05870
Phenolic acid decarboxylase (PAD); This family consists of several bacterial phenolic acid ...
9-166 2.53e-120

Phenolic acid decarboxylase (PAD); This family consists of several bacterial phenolic acid decarboxylase proteins. Phenolic acids, also called substituted cinnamic acids, are important lignin-related aromatic acids and natural constituents of plant cell walls. These acids (particularly ferulic, p-coumaric, and caffeic acids) bind the complex lignin polymer to the hemicellulose and cellulose in plants. The Phenolic acid decarboxylase (PAD) gene (pad) is transcriptionally regulated by p-coumaric, ferulic, or caffeic acid; these three acids are the three substrates of PAD.


Pssm-ID: 399105  Cd Length: 158  Bit Score: 335.85  E-value: 2.53e-120
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447253739   9 LSGFIGKHLVYTYDNGWNYEIYVKNGHTLDYRIHSGIVGNRWVKDQEAYIVRVGESIYKISWTEPTGTDVSLIVNLGDKL 88
Cdd:pfam05870   1 LSGFVGKHFIYTYDNGWEYEIYVKNEHTIDYRIHSGMVGGRWVKDQRVYIVRVGEGVYKVSWTEPTGTDVSLIVNLEDKR 80
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1447253739  89 FHGTIFFPRWIMNNPEKTVCFQNDHIPLMNSYRDAGPAYPTEVIDEFATITFIRDCGADNDEVINCPASELPADFPAN 166
Cdd:pfam05870  81 LHGTIFFPRWVEEHPEKTVCFQNDHIDLMEAYRDAGPTYPTEVIDEFATITFIEDCGIDNETVIACAPSELPAGYPAN 158
PAD cd14241
Phenolic Acid Decarboxylase; This family of bacterial and fungal phenolic acid decarboxylases ...
12-155 5.92e-98

Phenolic Acid Decarboxylase; This family of bacterial and fungal phenolic acid decarboxylases catalyzes the non-oxidative decarboxylation of phenolic acids to produce 4-vinyl derivates. Phenolic acid, like ferulic, p-coumaric, and caffeic acids, are important lignin-related aromatic acids and are natural constituents of plant cell walls. They act as crosslinkers between lignin polymers and hemicellulose/cellulose in plants. Their degradation is important from a biotechnological viewpoint.


Pssm-ID: 260131  Cd Length: 144  Bit Score: 278.77  E-value: 5.92e-98
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447253739  12 FIGKHLVYTYDNGWNYEIYVKNGHTLDYRIHSGIVGNRWVKDQEAYIVRVGESIYKISWTEPTGTDVSLIVNLGDKLFHG 91
Cdd:cd14241     1 FVGKHFVYTYDNGWEYEIYVKNENTIDYRIHGGPVGGRWVKDQTVYIVRIREGVYKISWTEPTGTDVSLIFNLVEKRIHG 80
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1447253739  92 TIFFPRWIMNNPEKTVCFQNDHIPLMNSYRDAGPAYPTEVIDEFATITFIRDCGADNDEVINCP 155
Cdd:cd14241    81 TIFFPKWVWEHPEKTVCYQNDHIDLMRAYREAGPTYPKYVVPEFATITFIEDCGGDDETVIACA 144
 
Name Accession Description Interval E-value
PadC COG3479
Phenolic acid decarboxylase [Secondary metabolites biosynthesis, transport and catabolism];
1-167 9.99e-126

Phenolic acid decarboxylase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 442702  Cd Length: 168  Bit Score: 349.68  E-value: 9.99e-126
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447253739   1 MSTFDKHDLSGFIGKHLVYTYDNGWNYEIYVKNGHTLDYRIHSGIVGNRWVKDQEAYIVRVGESIYKISWTEPTGTDVSL 80
Cdd:COG3479     1 MPTFPQHDLSGFVGKHFIYTYDNGWEYEIYVKNAHTIDYRIHSGMVGGRWVKDQRVDIVRLGEGIYKVSWTEPTGTDVSL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447253739  81 IVNLGDKLFHGTIFFPRWIMNNPEKTVCFQNDHIPLMNSYRDAGPAYPTEVIDEFATITFIRDCGADNDEVINCPASELP 160
Cdd:COG3479    81 DFNLNDRVLHGTIFFPRWVVDHPEKTVCFQNDHLDLMREYRDAGPTYPTEVIDEFATITFIEDCGADNEDVISCAPSELP 160

                  ....*..
gi 1447253739 161 ADFPANL 167
Cdd:COG3479   161 AGYPDRL 167
PA_decarbox pfam05870
Phenolic acid decarboxylase (PAD); This family consists of several bacterial phenolic acid ...
9-166 2.53e-120

Phenolic acid decarboxylase (PAD); This family consists of several bacterial phenolic acid decarboxylase proteins. Phenolic acids, also called substituted cinnamic acids, are important lignin-related aromatic acids and natural constituents of plant cell walls. These acids (particularly ferulic, p-coumaric, and caffeic acids) bind the complex lignin polymer to the hemicellulose and cellulose in plants. The Phenolic acid decarboxylase (PAD) gene (pad) is transcriptionally regulated by p-coumaric, ferulic, or caffeic acid; these three acids are the three substrates of PAD.


Pssm-ID: 399105  Cd Length: 158  Bit Score: 335.85  E-value: 2.53e-120
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447253739   9 LSGFIGKHLVYTYDNGWNYEIYVKNGHTLDYRIHSGIVGNRWVKDQEAYIVRVGESIYKISWTEPTGTDVSLIVNLGDKL 88
Cdd:pfam05870   1 LSGFVGKHFIYTYDNGWEYEIYVKNEHTIDYRIHSGMVGGRWVKDQRVYIVRVGEGVYKVSWTEPTGTDVSLIVNLEDKR 80
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1447253739  89 FHGTIFFPRWIMNNPEKTVCFQNDHIPLMNSYRDAGPAYPTEVIDEFATITFIRDCGADNDEVINCPASELPADFPAN 166
Cdd:pfam05870  81 LHGTIFFPRWVEEHPEKTVCFQNDHIDLMEAYRDAGPTYPTEVIDEFATITFIEDCGIDNETVIACAPSELPAGYPAN 158
PAD cd14241
Phenolic Acid Decarboxylase; This family of bacterial and fungal phenolic acid decarboxylases ...
12-155 5.92e-98

Phenolic Acid Decarboxylase; This family of bacterial and fungal phenolic acid decarboxylases catalyzes the non-oxidative decarboxylation of phenolic acids to produce 4-vinyl derivates. Phenolic acid, like ferulic, p-coumaric, and caffeic acids, are important lignin-related aromatic acids and are natural constituents of plant cell walls. They act as crosslinkers between lignin polymers and hemicellulose/cellulose in plants. Their degradation is important from a biotechnological viewpoint.


Pssm-ID: 260131  Cd Length: 144  Bit Score: 278.77  E-value: 5.92e-98
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447253739  12 FIGKHLVYTYDNGWNYEIYVKNGHTLDYRIHSGIVGNRWVKDQEAYIVRVGESIYKISWTEPTGTDVSLIVNLGDKLFHG 91
Cdd:cd14241     1 FVGKHFVYTYDNGWEYEIYVKNENTIDYRIHGGPVGGRWVKDQTVYIVRIREGVYKISWTEPTGTDVSLIFNLVEKRIHG 80
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1447253739  92 TIFFPRWIMNNPEKTVCFQNDHIPLMNSYRDAGPAYPTEVIDEFATITFIRDCGADNDEVINCP 155
Cdd:cd14241    81 TIFFPKWVWEHPEKTVCYQNDHIDLMRAYREAGPTYPKYVVPEFATITFIEDCGGDDETVIACA 144
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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