NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2017777509|gb|QTG10078|]
View 

sugar ABC transporter permease [Rhizobium rhizogenes]

Protein Classification

carbohydrate ABC transporter permease( domain architecture ID 10003067)

carbohydrate ABC transporter permease is the transmembrane (TM) subunit of a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter responsible for the translocation across the membrane of one or more from a variety of carbohydrate substrates including trehalose, lactose, arabinose, and maltodextrin

Gene Ontology:  GO:0042626|GO:0140359|GO:0008643|GO:0055085
PubMed:  25750732|24638992|30626703
TCDB:  3.A.1.1.-

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
1-269 1.00e-88

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


:

Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 265.46  E-value: 1.00e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509   1 MFLVYVILPVFQSVWISFHDWDGLGPK-TWIGLGNYVELFSDDAFYTSLENNIIWLVLYL-LAVPAGLAAALFLNQTVAG 78
Cdd:COG1175    30 LLLVFVLYPLLYTLYLSFTDWNLLGPPpEFVGLDNYARLFTDPRFWNALGNTLLFTVVSVpLQLVLGLLLALLLNRKLRG 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509  79 IRIYKSLFFFPFVISQVVVGLIFTWFYAPNFGLFSVLTEALTGTQIAILADERLVTYGIIAAGLWPQIAYCMILYLTGLN 158
Cdd:COG1175   110 RGFFRTLFFLPWVISPVVVALIWKWLFNPDYGLLNALLGALGLEPINWLGDPSLALPAVIIVTVWKGTGFNMLIFLAGLQ 189

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509 159 NINPEQIEAGRMDGAKGWHLFWNIVLPQLRPATFIAVVVTVIGALRSFDLVSVMTAGGPYGSSRVLSYYMYEEALSeyGF 238
Cdd:COG1175   190 SIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIGALQVFDLVYVLTGGGPGNSTTTLVLYIYQTAFQ--QF 267

                         250       260       270
                  ....*....|....*....|....*....|.
gi 2017777509 239 RMGYGAAIAVVLFLIMMIFITFFLIRMLRQE 269
Cdd:COG1175   268 DFGYASAIAVVLFLIILVLTLLQLRLLRRRE 298
 
Name Accession Description Interval E-value
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
1-269 1.00e-88

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 265.46  E-value: 1.00e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509   1 MFLVYVILPVFQSVWISFHDWDGLGPK-TWIGLGNYVELFSDDAFYTSLENNIIWLVLYL-LAVPAGLAAALFLNQTVAG 78
Cdd:COG1175    30 LLLVFVLYPLLYTLYLSFTDWNLLGPPpEFVGLDNYARLFTDPRFWNALGNTLLFTVVSVpLQLVLGLLLALLLNRKLRG 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509  79 IRIYKSLFFFPFVISQVVVGLIFTWFYAPNFGLFSVLTEALTGTQIAILADERLVTYGIIAAGLWPQIAYCMILYLTGLN 158
Cdd:COG1175   110 RGFFRTLFFLPWVISPVVVALIWKWLFNPDYGLLNALLGALGLEPINWLGDPSLALPAVIIVTVWKGTGFNMLIFLAGLQ 189

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509 159 NINPEQIEAGRMDGAKGWHLFWNIVLPQLRPATFIAVVVTVIGALRSFDLVSVMTAGGPYGSSRVLSYYMYEEALSeyGF 238
Cdd:COG1175   190 SIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIGALQVFDLVYVLTGGGPGNSTTTLVLYIYQTAFQ--QF 267

                         250       260       270
                  ....*....|....*....|....*....|.
gi 2017777509 239 RMGYGAAIAVVLFLIMMIFITFFLIRMLRQE 269
Cdd:COG1175   268 DFGYASAIAVVLFLIILVLTLLQLRLLRRRE 298
PRK10561 PRK10561
sn-glycerol-3-phosphate ABC transporter permease UgpA;
4-256 1.63e-20

sn-glycerol-3-phosphate ABC transporter permease UgpA;


Pssm-ID: 182550 [Multi-domain]  Cd Length: 280  Bit Score: 88.34  E-value: 1.63e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509   4 VYVILPVFQSVWISFHDWDGLG-PKTWIGLGNYVELFSDDAFYTSLENNIIWLVLYLLAvpaGLAAALFL----NQTVAG 78
Cdd:PRK10561   12 IFFIWPAGEALWYSLQSVDPFGfSSQFVGLDNFVALFHDSYYLDSFWTTIKFSTLVTVS---GLLVSLFFaalvDYVVRG 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509  79 IRIYKSLFFFPFVISQVVVGLIFTWFYAPNFGLFSVLTEALtGTQIAILADERLVTYGIIAAGLWPQIAYCMILYLTGLN 158
Cdd:PRK10561   89 SRFYQTLMLLPYAVAPAVAAVLWIFLFNPGRGLITHFLAEF-GYDWNHAQNSGQAMFLVVFASVWKQISYNFLFFFAALQ 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509 159 NINPEQIEAGRMDGAKGWHLFWNIVLPQLRPATFIAVVVTVIGA-LRSFDLVSVMTAGGPYGSSRVLSYYMYEEALSeyG 237
Cdd:PRK10561  168 SIPRSLVEAAAIDGAGPIRRFFKLALPLIAPVSFFLLVVNLVYAfFDTFPVIDAATSGGPVQATTTLIYKIYREGFT--G 245

                         250
                  ....*....|....*....
gi 2017777509 238 FRMGYGAAIAVVLFLIMMI 256
Cdd:PRK10561  246 LDLSSSAAQSVVLMFLVIV 264
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 86-266 1.34e-10

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 58.85  E-value: 1.34e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509  86 FFFPFVISQVVVGLIFTWFYAPNFGLFSVLTEaltgtqIAILADERLVTYGIIAAGLWPQIAYCMILYLTGLNNINPEQI 165
Cdd:pfam00528  10 LRRGRRLDRLLRPLIDLLQALPSFVLAILLVV------IAILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSDLV 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509 166 EAGRMDGAKGWHLFWNIVLPQLRPATFIAVVVTVIGALRSFDLVSVMTAGGPYGssrvlsyYMYEEALSEYGFRMGYGAA 245
Cdd:pfam00528  84 EAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLG-------LLLIEAILGYDYPEIQGPV 156

                         170       180
                  ....*....|....*....|.
gi 2017777509 246 IAVVLFLIMMIFITFFLIRML 266
Cdd:pfam00528 157 LAAALILLLLNLLVDILQRLL 177
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 59-254 1.31e-09

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 56.13  E-value: 1.31e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509  59 LLAVPAGLAAALFLNQTVAGI-RIYKSLFFFPFVISQVVVGLIFTWFYAPNFGLFSVLTEALTGtqiailaderlvtygI 137
Cdd:cd06261    13 LLALVLGLLLGIILARKRGKLdRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGLGLPA---------------L 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509 138 IAAGLWpQIAYCMILYLTGLNNINPEQIEAGRMDGAKGWHLFWNIVLPQLRPATFIAVVVTVIGALRSFDLVSVMTAGGP 217
Cdd:cd06261    78 ILALLL-IAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEA 156

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 2017777509 218 YGssrvLSYYMYEEALSEYGFRMGYGAAIAVVLFLIM 254
Cdd:cd06261   157 PG----PGTGLLLIFAILFPGDLGVAAAVALILLLLS 189
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 2-272 7.24e-07

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 50.06  E-value: 7.24e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509   2 FLVYVILPVFQSVWISFHDWDGlgpkTWIGLGNYVELFSDDAFYTSLENNI-IWLVLYLLAVPAGLAAALFLNQT-VAGI 79
Cdd:TIGR03262  14 LLLFLLLPLLALLTKSVYDSDG----DFIGLANFAEYFATPGLLQSLGNSLtVSAIVTAIVVPLAFAFAYALTRSrIPGK 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509  80 RIYKSLFFFPFVISQVVVGLIFTWFyapnFGLFSVLTEALTGTQIAILaderlvtYGIIAAGLWPQIAYCMILYLTGLNN 159
Cdd:TIGR03262  90 GAFRLVALLPLLAPSLLPAISLIYL----FGNQGLLKGLLGGFSIYGF-------WGIVIGEVFYTFPHALMILVTALSL 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509 160 INPEQIEAGRMDGAKGWHLFWNIVLPQLRPATFIAVVVTVIGALRSFDLVSVMtaGGPYGssrVLSYYMYEEALSEYGFR 239
Cdd:TIGR03262 159 ADGRLYEAARAMGASPWRTFFTVTLPGAKYGLISAAFVVFTLVITDFGVPKVI--GGDYN---VLATDIYKQVIGQQNFP 233

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 2017777509 240 MgyGAAIAVVLFL--IMMIFITFFLIRMLRQERNS 272
Cdd:TIGR03262 234 M--GAVVGVLLLLpaLLAFGIDRAIQRRQRAQLSS 266
 
Name Accession Description Interval E-value
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
1-269 1.00e-88

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 265.46  E-value: 1.00e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509   1 MFLVYVILPVFQSVWISFHDWDGLGPK-TWIGLGNYVELFSDDAFYTSLENNIIWLVLYL-LAVPAGLAAALFLNQTVAG 78
Cdd:COG1175    30 LLLVFVLYPLLYTLYLSFTDWNLLGPPpEFVGLDNYARLFTDPRFWNALGNTLLFTVVSVpLQLVLGLLLALLLNRKLRG 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509  79 IRIYKSLFFFPFVISQVVVGLIFTWFYAPNFGLFSVLTEALTGTQIAILADERLVTYGIIAAGLWPQIAYCMILYLTGLN 158
Cdd:COG1175   110 RGFFRTLFFLPWVISPVVVALIWKWLFNPDYGLLNALLGALGLEPINWLGDPSLALPAVIIVTVWKGTGFNMLIFLAGLQ 189

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509 159 NINPEQIEAGRMDGAKGWHLFWNIVLPQLRPATFIAVVVTVIGALRSFDLVSVMTAGGPYGSSRVLSYYMYEEALSeyGF 238
Cdd:COG1175   190 SIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIGALQVFDLVYVLTGGGPGNSTTTLVLYIYQTAFQ--QF 267

                         250       260       270
                  ....*....|....*....|....*....|.
gi 2017777509 239 RMGYGAAIAVVLFLIMMIFITFFLIRMLRQE 269
Cdd:COG1175   268 DFGYASAIAVVLFLIILVLTLLQLRLLRRRE 298
PRK10561 PRK10561
sn-glycerol-3-phosphate ABC transporter permease UgpA;
4-256 1.63e-20

sn-glycerol-3-phosphate ABC transporter permease UgpA;


Pssm-ID: 182550 [Multi-domain]  Cd Length: 280  Bit Score: 88.34  E-value: 1.63e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509   4 VYVILPVFQSVWISFHDWDGLG-PKTWIGLGNYVELFSDDAFYTSLENNIIWLVLYLLAvpaGLAAALFL----NQTVAG 78
Cdd:PRK10561   12 IFFIWPAGEALWYSLQSVDPFGfSSQFVGLDNFVALFHDSYYLDSFWTTIKFSTLVTVS---GLLVSLFFaalvDYVVRG 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509  79 IRIYKSLFFFPFVISQVVVGLIFTWFYAPNFGLFSVLTEALtGTQIAILADERLVTYGIIAAGLWPQIAYCMILYLTGLN 158
Cdd:PRK10561   89 SRFYQTLMLLPYAVAPAVAAVLWIFLFNPGRGLITHFLAEF-GYDWNHAQNSGQAMFLVVFASVWKQISYNFLFFFAALQ 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509 159 NINPEQIEAGRMDGAKGWHLFWNIVLPQLRPATFIAVVVTVIGA-LRSFDLVSVMTAGGPYGSSRVLSYYMYEEALSeyG 237
Cdd:PRK10561  168 SIPRSLVEAAAIDGAGPIRRFFKLALPLIAPVSFFLLVVNLVYAfFDTFPVIDAATSGGPVQATTTLIYKIYREGFT--G 245

                         250
                  ....*....|....*....
gi 2017777509 238 FRMGYGAAIAVVLFLIMMI 256
Cdd:PRK10561  246 LDLSSSAAQSVVLMFLVIV 264
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
2-270 2.98e-17

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 80.98  E-value: 2.98e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509   2 FLVYVILPVFQSVWISFHDwdglgpktwiGLGNYVELFSDDAFYTSLENNIiWLVLY--LLAVPAGLAAALFLNQT-VAG 78
Cdd:COG1178    20 LALLVLLPLLALLLRAFTD----------GLANFWALLSDPYLWRALGNTL-LLALLvtLLSLLLGVPLAWLLARTdFPG 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509  79 IRIYKSLFFFPFVISQVVVGLIFTWFYAPNfGLFSVLTEALTGTQIAILaderlvtYG----IIAAGLWpQIAYCMILYL 154
Cdd:COG1178    89 RRLLRWLLLLPLALPPYVVALAWIALFGPN-GLLNTLLRALFGLEPPDI-------YGlggiILVLVLF-NYPYVYLLLR 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509 155 TGLNNINPEQIEAGRMDGAKGWHLFWNIVLPQLRPATFIAVVVTVIGALRSFDLVSVMtaGGPYgssRVLSYYMYEEALS 234
Cdd:COG1178   160 AALRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAIAAGALLVFLLCLADFGTPLVL--GGGY---TTLTTAIYQAWLG 234

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 2017777509 235 EYGFRMgyGAAIAVVLFLImmIFITFFLIRMLRQER 270
Cdd:COG1178   235 DFDLGA--AAALALVLLLL--VLLLLLLERRLRRRR 266
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 1-270 6.99e-17

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 78.27  E-value: 6.99e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509   1 MFLVYVILPVFQSVWISFHDWDGLGPKTW-IGLGNYVELFSDDAFYTSLENNI-IWLVLYLLAVPAGLAAALFLNQTVAG 78
Cdd:COG1176    21 WLLLFFVLPLLLLLVYSFTTRDPYGGVVPgFTLENYARLFTDPLYLKVLLRTLwIALLTTLICLLLGYPIAYFLARAPPR 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509  79 IR-IYKSLFFFPFVISQVVVGLIFTWFYAPNfGLFSVLTEA--LTGTQIAILADERlvtyGIIAAGLWPQIAYCMILYLT 155
Cdd:COG1176   101 WRnLLLLLVILPFWTSFLVRTYAWIVLLGRN-GLLNSLLLAlgLIDEPLRLLYTEF----AVVIGLVYVYLPFMVLPLYA 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509 156 GLNNINPEQIEAGRMDGAKGWHLFWNIVLPQLRPATFIAVVVTVIGALRSFDLVSVMtaGGPygSSRVLSYYMYEEALSe 235
Cdd:COG1176   176 ALEKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLVFIPALGAFVTPALL--GGG--KVLMIGNLIYQQFLS- 250

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 2017777509 236 yGFRMGYGAAIAVVLFLIMMIFITFFLIRMLRQER 270
Cdd:COG1176   251 -ALNWPLAAALAVVLLLIVLLVLLLYLRLLRRRRL 284
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 2-272 3.02e-14

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 70.53  E-value: 3.02e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509   2 FLVYVILPVFQSVWISFHD-WDGLGPKTWIGLGNYVELFSDDAFYTSLENN-IIWLVLYLLAVPAGLAAALFLNQT-VAG 78
Cdd:COG1177    16 VLLFLYLPILVLVLYSFNDsWFLTFPPEGFTLRWYAELFSDPRLLDALLNSlLIALLSTLLATVLGTPAALALARYrFRG 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509  79 IRIYKSLFFFPFVISQVVVGL-IFTWFYAPNFglfsvltealtgtqiailadeRLVTYGIIAAGLWPQIAYCMILYLTGL 157
Cdd:COG1177    96 RRLLLALLLLPLVVPGIVLGVaLLLLFSALGL---------------------SGGLWGLILAHVVFTLPFVVLVVLARL 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509 158 NNINPEQIEAGRMDGAKGWHLFWNIVLPQLRPATFIAVVVTVIgalRSFD--LVSVMTAGgpyGSSRVLSYYMYEEAlsE 235
Cdd:COG1177   155 QGFDPSLEEAARDLGASPWQTFRRVTLPLIAPGILAGALLAFT---LSFDefVITLFLAG---PGVTTLPVYIYSMI--R 226

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 2017777509 236 YGFRmGYGAAIAVVLFLIMMIFITFFLIRMLRQERNS 272
Cdd:COG1177   227 RGIS-PEINALSTLLILLSLLLLLLAERLRRRGERRR 262
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
2-261 9.05e-12

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 64.80  E-value: 9.05e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509   2 FLVYVILPVFQSVWISFHDWDGLGpktwIGLGNYVELFSDDAFYTSLENNIIWLVL-YLLAVPAGLAAALFLNQT-VAGI 79
Cdd:COG1178   298 VLLGLLLPLLALLLWSLTKALDDN----LTLDNYRFVLLDPSLLRALLNSLLLALLaALLAVLLALLLAYLVRRRrGRLA 373

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509  80 RIYKSLFFFPFVISQVVVGLIFTWFYAPNFGLFsvlteaLTGTQIAILaderlVTYGIIAaglwpqIAYCMILYLTGLNN 159
Cdd:COG1178   374 RLLDRLAMLPYAVPGIVLGLGLLLLFNRPLPLL------LYGTLAILV-----LAYVVRF------LPFALRSLEAALAQ 436

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509 160 INPEQIEAGRMDGAKGWHLFWNIVLPQLRPATFIAVVVTVIGALRSFDLVSVMTAGGpygsSRVLSYYMYEEALSEygfR 239
Cdd:COG1178   437 IDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALLVFVTSMKELSATLLLRPPG----FETLAVLIYQLASSG---R 509

                         250       260
                  ....*....|....*....|..
gi 2017777509 240 MGYGAAIAVVLFLIMMIFITFF 261
Cdd:COG1178   510 YGEAAALALLLVLVSLLPVLLL 531
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 86-266 1.34e-10

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 58.85  E-value: 1.34e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509  86 FFFPFVISQVVVGLIFTWFYAPNFGLFSVLTEaltgtqIAILADERLVTYGIIAAGLWPQIAYCMILYLTGLNNINPEQI 165
Cdd:pfam00528  10 LRRGRRLDRLLRPLIDLLQALPSFVLAILLVV------IAILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSDLV 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509 166 EAGRMDGAKGWHLFWNIVLPQLRPATFIAVVVTVIGALRSFDLVSVMTAGGPYGssrvlsyYMYEEALSEYGFRMGYGAA 245
Cdd:pfam00528  84 EAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLG-------LLLIEAILGYDYPEIQGPV 156

                         170       180
                  ....*....|....*....|.
gi 2017777509 246 IAVVLFLIMMIFITFFLIRML 266
Cdd:pfam00528 157 LAAALILLLLNLLVDILQRLL 177
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 59-254 1.31e-09

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 56.13  E-value: 1.31e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509  59 LLAVPAGLAAALFLNQTVAGI-RIYKSLFFFPFVISQVVVGLIFTWFYAPNFGLFSVLTEALTGtqiailaderlvtygI 137
Cdd:cd06261    13 LLALVLGLLLGIILARKRGKLdRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGLGLPA---------------L 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509 138 IAAGLWpQIAYCMILYLTGLNNINPEQIEAGRMDGAKGWHLFWNIVLPQLRPATFIAVVVTVIGALRSFDLVSVMTAGGP 217
Cdd:cd06261    78 ILALLL-IAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEA 156

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 2017777509 218 YGssrvLSYYMYEEALSEYGFRMGYGAAIAVVLFLIM 254
Cdd:cd06261   157 PG----PGTGLLLIFAILFPGDLGVAAAVALILLLLS 189
malF PRK10999
maltose ABC transporter permease MalF;
28-253 3.64e-08

maltose ABC transporter permease MalF;


Pssm-ID: 236816 [Multi-domain]  Cd Length: 520  Bit Score: 53.81  E-value: 3.64e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509  28 TWIGLGNYVELFSDDAFYTSLENNIIWLVLY-LLAVPAGLAAALFLN-----QTVAGIRIYKSLFFFPFVISQVVVGLIF 101
Cdd:PRK10999  263 VTIGWKNFTRVFTDEGIQKPFIAIFIWTVVFsLLTVVLTVAVGMVLAclvqwEALKGKAVYRVLLILPYAVPSFISILIF 342

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509 102 TWFYAPNFGLFSVLTEALTGTQIAILADERLVTYGIIAAGLWPQIAYCMILYLTGLNNINPEQIEAGRMDGAKGWHLFWN 181
Cdd:PRK10999  343 KGLFNQSFGEINMMLSALFGIKPAWFSDPTLAKTMILIVNTWLGYPYMMILCMGLLKAIPDDLYEASAMDGAGPFQNFFK 422

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509 182 IVLPQL-RPAT--FIAvvvTVIGALRSFDLVSVMTAGGP--YGSSRVLSY------YMYEEALSEYGFR-MGYGAAIAVV 249
Cdd:PRK10999  423 ITLPLLiKPLTplMIA---SFAFNFNNFVLIQLLTNGGPdmIGTTTPAGYtdllvsYTYRIAFEGGGGQdFGLAAAIATL 499


                  ....
gi 2017777509 250 LFLI 253
Cdd:PRK10999  500 IFLL 503
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 2-261 4.99e-07

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 49.71  E-value: 4.99e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509   2 FLVYVILPVFQSVWISFHDWDGL--GPKTWI----GLGNYVELFSDDAFYTSLENNII-----WLVLYLLAVPAGLAAAL 70
Cdd:COG0395    24 LALLFLFPLYWMVVTSFKPPAEIfsGPPSLLpsefTLENYRAAFTDGPFGRYLLNSLIvavvsTVLSLLLSSLAAYALAR 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509  71 FlnqTVAGiriyKSLFFFPFVISQVV---VGLIftwfyaPNFGLFSVLteALTGTQIailaderlvtyGIIAAGLWPQIA 147
Cdd:COG0395   104 F---RFRG----RKLLFLLILATLMIpgqVLLI------PLYLLFRQL--GLLNTYW-----------GLILPYLAFGLP 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509 148 YCMILYLTGLNNINPEQIEAGRMDGAKGWHLFWNIVLPQLRPATFIAVVVTVIGALRSFDLVSVMTAGgpyGSSRVLSYY 227
Cdd:COG0395   158 FGIFLLRQFFRSIPRELEEAARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTS---PDLRTLPVG 234

                         250       260       270
                  ....*....|....*....|....*....|....
gi 2017777509 228 MYeEALSEYGFRMGYGAAIAVVLFLIMMIFITFF 261
Cdd:COG0395   235 LA-SFQGQYGTDWGLLMAAAVIATLPVLILFLFL 267
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 2-272 7.24e-07

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 50.06  E-value: 7.24e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509   2 FLVYVILPVFQSVWISFHDWDGlgpkTWIGLGNYVELFSDDAFYTSLENNI-IWLVLYLLAVPAGLAAALFLNQT-VAGI 79
Cdd:TIGR03262  14 LLLFLLLPLLALLTKSVYDSDG----DFIGLANFAEYFATPGLLQSLGNSLtVSAIVTAIVVPLAFAFAYALTRSrIPGK 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509  80 RIYKSLFFFPFVISQVVVGLIFTWFyapnFGLFSVLTEALTGTQIAILaderlvtYGIIAAGLWPQIAYCMILYLTGLNN 159
Cdd:TIGR03262  90 GAFRLVALLPLLAPSLLPAISLIYL----FGNQGLLKGLLGGFSIYGF-------WGIVIGEVFYTFPHALMILVTALSL 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509 160 INPEQIEAGRMDGAKGWHLFWNIVLPQLRPATFIAVVVTVIGALRSFDLVSVMtaGGPYGssrVLSYYMYEEALSEYGFR 239
Cdd:TIGR03262 159 ADGRLYEAARAMGASPWRTFFTVTLPGAKYGLISAAFVVFTLVITDFGVPKVI--GGDYN---VLATDIYKQVIGQQNFP 233

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 2017777509 240 MgyGAAIAVVLFL--IMMIFITFFLIRMLRQERNS 272
Cdd:TIGR03262 234 M--GAVVGVLLLLpaLLAFGIDRAIQRRQRAQLSS 266
cysW PRK11602
sulfate/thiosulfate ABC transporter permease CysW;
53-213 2.07e-04

sulfate/thiosulfate ABC transporter permease CysW;


Pssm-ID: 183225  Cd Length: 283  Bit Score: 42.05  E-value: 2.07e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509  53 IWLVLY--LLAVPAGLAAALFLNQTVA-----GIRIYKSLFFFPFVISQVVVGLIFTWFYAPNFGLFSVLTEaltgtqia 125
Cdd:PRK11602   66 IWLTVLiaLIAVPVNLVFGILLAWLVTrfnfpGRQLLLTLLDIPFAVSPVVAGLVYLLFYGSNGPLGGWLDE-------- 137

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2017777509 126 iladerlvtYGIIAAGLWPQIAYCMI----------LYLTGLNNINPEQiEAGRMDGAKGWHLFWNIVLPQLRPATFIAV 195
Cdd:PRK11602  138 ---------HNLQLMFSWPGMVLVTIfvtcpfvvreLVPVMLSQGSQED-EAAILLGASGWQMFRRVTLPNIRWALLYGV 207

                         170
                  ....*....|....*...
gi 2017777509 196 VVTVIGALRSFDLVSVMT 213
Cdd:PRK11602  208 VLTNARAIGEFGAVSVVS 225
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH