|
Name |
Accession |
Description |
Interval |
E-value |
| TrwC |
pfam08751 |
TrwC relaxase; Relaxases are DNA strand transferases which function during the conjugative ... |
9-400 |
2.80e-78 |
|
TrwC relaxase; Relaxases are DNA strand transferases which function during the conjugative cell to cell DNA transfer. TrwC binds to the origin of transfer (oriT) and melts the double helix.
Pssm-ID: 430190 [Multi-domain] Cd Length: 279 Bit Score: 260.24 E-value: 2.80e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 9 SGTGYEYLLRSVAtndgptdapslskYYDAKGTPPGRWLGSGLAGLNTEnvvqgGEVTESQMAALYgEGLHPDADmkmse 88
Cdd:pfam08751 1 AGDAYAYYTRQDD-------------YYTEGGEPPGRWLGKGAAALGLS-----GEVTEEQFEALL-EGRHPDTG----- 56
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 89 gqkikdVQLGRPFanftndvpvlvalrdaerrhrqttgtlmgkqeraelvqdigreffieehgvepqsgreivnwvnglk 168
Cdd:pfam08751 57 ------ERLGRRR------------------------------------------------------------------- 63
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 169 DNVRQSVSGFDLTFSPAKSVSVVWALSDEEtarRIEKLHHQAVKEAMAWAEDNALFTRVGKQGR-EQVKTKGFVASEFKH 247
Cdd:pfam08751 64 PRGRKHRAGFDLTFSAPKSVSLLAAVGGDE---RIEAAHRAAVAEALAWLEKHAAQTRVGKDGGvEQVDTGGLVAAAFRH 140
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 248 YDTRAGDPDLHSHVLVSNKVQTEDGRWLSIDGYTLMKYHQSISHRYDSILNTLLSnEMGYTFTARdhgaNKEPTWEIEGV 327
Cdd:pfam08751 141 DTSRAGDPQLHTHVVVANVTQREDGKWRALDSRGLYKAQVAAGAVYRAELADELR-RLGYEIEER----GKRGVFEIAGV 215
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958407961 328 SESLMESFSKRRRGAQpvykRLVEEFVAARGTTPNSVEvgrlwQQAILETRDAKREPESLTELRAGWKAEVAA 400
Cdd:pfam08751 216 PEELIEAFSKRRAQIE----AELAELGATHGRAPPAAR-----QIAALETRPAKHEPRSLAELRARWREEAAE 279
|
|
| RecD |
COG0507 |
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) ... |
487-942 |
1.79e-69 |
|
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];
Pssm-ID: 440273 [Multi-domain] Cd Length: 514 Bit Score: 243.35 E-value: 1.79e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 487 RDKAISLNDFDVLELPEALKNSAGKARDARADSELYTTQdILDTEDKALGALNEPVAAFAPSAAIDKALDEHEAESGFRL 566
Cdd:COG0507 47 LEDLAAARLLGVAEDIEAALAALVESGPLVLDGRRYLTR-LLEAEQRLARRLRRLARPALDEADVEAALAALEPRAGITL 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 567 NAGQESMARYLLTCGTLAAtGVGPAGTGKTASMRLVANVWANQGRNVIGLAPSAQAAEVLSGDLGFDAFTIDKLTYtWRG 646
Cdd:COG0507 126 SDEQREAVALALTTRRVSV-LTGGAGTGKTTTLRALLAALEALGLRVALAAPTGKAAKRLSESTGIEARTIHRLLG-LRP 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 647 NHPTKPGHSLKDLpvsiNAGDMIIVDEAGMASTPNIGSLLEIAEEAGAVVRFIGDHKQLGAVENGGLFGAMVNAAGRTDN 726
Cdd:COG0507 204 DSGRFRHNRDNPL----TPADLLVVDEASMVDTRLMAALLEALPRAGARLILVGDPDQLPSVGAGAVLRDLIESGTVPVV 279
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 727 QLSEVVRFGGDSAQSATSLRLREGDSSTF--DFYLERGWVNGGARSDMLDKAAADYLADISSGKTSLLIAATNRDVAELN 804
Cdd:COG0507 280 ELTEVYRQADDSRIIELAHAIREGDAPEAlnARYADVVFVEAEDAEEAAEAIVELYADRPAGGEDIQVLAPTNAGVDALN 359
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 805 ETIRAHYIAVGVVDTTVEAqlSRGEKAGVGDTILARKNQtfYDDetatstRINNGTLLTVTAIAEN-GSITARNtaTGEE 883
Cdd:COG0507 360 QAIREALNPAGELERELAE--DGELELYVGDRVMFTRND--YDL------GVFNGDIGTVLSIDEDeGRLTVRF--DGRE 427
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958407961 884 LCLPADYVHDNVQLGYAATVHRAQGSTVDCTRAVIDYH----VDRAGLYVALTRGKIANHIYA 942
Cdd:COG0507 428 IVTYDPSELDQLELAYAITVHKSQGSTFDRVILVLPSEhsplLSRELLYTALTRARELLTLVG 490
|
|
| AAA_30 |
pfam13604 |
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ... |
565-767 |
2.52e-57 |
|
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. There is a Walker A and Walker B.
Pssm-ID: 433343 [Multi-domain] Cd Length: 191 Bit Score: 196.63 E-value: 2.52e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 565 RLNAGQESMARYLLTCGTLAATGVGPAGTGKTASMRLVANVWANQGRNVIGLAPSAQAAEVLSGDLGFDAFTIDKLTYTW 644
Cdd:pfam13604 1 TLNAEQAAAVRALLTSGDRVAVLVGPAGTGKTTALKALREAWEAAGYRVIGLAPTGRAAKVLGEELGIPADTIAKLLHRL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 645 RGnhptkpghslkdlPVSINAGDMIIVDEAGMASTPNIGSLLEIAEEAGAVVRFIGDHKQLGAVENGGLFGAMVnAAGRT 724
Cdd:pfam13604 81 GG-------------RAGLDPGTLLIVDEAGMVGTRQMARLLKLAEDAGARVILVGDPRQLPSVEAGGAFRDLL-AAGIG 146
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1958407961 725 DNQLSEVVRFgGDSAQSATSLRLREGD-SSTFDFYLERGWVNGG 767
Cdd:pfam13604 147 TAELTEIVRQ-RDPWQRAASLALRDGDpAEALDALADRGRIHEG 189
|
|
| MobF |
NF041492 |
MobF family relaxase; |
1-397 |
4.04e-55 |
|
MobF family relaxase;
Pssm-ID: 469380 [Multi-domain] Cd Length: 288 Bit Score: 194.06 E-value: 4.04e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 1 MMTLRVVNS-GTGYEYLLRSVATNdgptdapslskYY-DAKGTPPGRWLGSGLAGLNtenvVQGGEVTESQMAALYgEGL 78
Cdd:NF041492 1 MLSIARIGSaGGAARYYTEKDLDN-----------YYsEDGGTPAGRWFGKGAEALG----LSGGAVDGERFKALL-DGR 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 79 HPDadmkmseGQKIKDVQLGrpfanftndvpvlvalrdaERRHRqttgtlmgkqeraelvqdigreffieehgvepqsgr 158
Cdd:NF041492 65 LPD-------GERLRRRRKG-------------------AGRHR------------------------------------ 82
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 159 eivnwvnglkdnvrqsvSGFDLTFSPAKSVSVVWALSDEetaRRIEKLHHQAVKEAMAWAEDNALFTRVGKQGR---EQV 235
Cdd:NF041492 83 -----------------PGYDLTFSAPKSVSLLALVGGD---KRLIEAHDEAVKEALEYLEERLAQTRVTVDGKgrtSLE 142
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 236 KTKGFVASEFKHYDTRAGDPDLHSHVLVSNKVQTEDGRWLSIDGYTLMKYHQSISHRYDSILNTLLSnEMGYTFTARDHG 315
Cdd:NF041492 143 KTGNLVAALFRHDTSRAGDPQLHTHAVVMNMTQRPDGKWRSLDNEELYKNQKALGAIYQAELAEELQ-ALGYEIRETKNG 221
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 316 ankepTWEIEGVSESLMESFSKRRRGaqpvykrlVEEFVAARGTTPNSVEVGrlwQQAILETRDAKREPESLTELRAGWK 395
Cdd:NF041492 222 -----QFEIAGVPREQIEAFSKRSQQ--------IEEWLGENPATLASAALR---QIAALDTRKAKEADVDPEELEAEWR 285
|
..
gi 1958407961 396 AE 397
Cdd:NF041492 286 EE 287
|
|
| TraA_Ti |
TIGR02768 |
Ti-type conjugative transfer relaxase TraA; This protein contains domains distinctive of a ... |
518-945 |
3.96e-48 |
|
Ti-type conjugative transfer relaxase TraA; This protein contains domains distinctive of a single strand exonuclease (N-terminus, MobA/MobL, pfam03389) as well as a helicase domain (central region, homologous to the corresponding region of the F-type relaxase TraI, TIGR02760). This protein likely fills the same role as TraI(F), nicking (at the oriT site) and unwinding the coiled plasmid prior to conjugative transfer.
Pssm-ID: 274289 [Multi-domain] Cd Length: 744 Bit Score: 185.40 E-value: 3.96e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 518 DSELYTTQDILDTE---DKALGALNEPVAAFAPSAAIDKALDEHeaesgFRLNAGQESMARYLLTCGTLAATgVGPAGTG 594
Cdd:TIGR02768 307 EPARFSTREMIRLEaqmARSAEALSQSQGHGVSPPIVDAAIDQH-----YRLSEEQYEAVRHVTGSGDIAVV-VGRAGTG 380
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 595 KTASMRLVANVWANQGRNVIGLAPSAQAAEVLSGDLGFDAFTIDKLTYTW-RGnhptkpghslKDLpvsINAGDMIIVDE 673
Cdd:TIGR02768 381 KSTMLKAAREAWEAAGYRVIGAALSGKAAEGLQAESGIESRTLASLEYAWaNG----------RDL---LSDKDVLVIDE 447
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 674 AGMASTPNIGSLLEIAEEAGAVVRFIGDHKQLGAVENGGLFGAMVNAAGRTdnQLSEVVRFGGDSAQSATSLRLREGDSS 753
Cdd:TIGR02768 448 AGMVGSRQMARVLKEAEEAGAKVVLVGDPEQLQPIEAGAAFRAIAERIGYA--ELETIRRQREAWARQASLELARGDVEK 525
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 754 TFDFYLERGWVNG-GARSDMLDKAAADYLADISSG---KTSLLIAATNRDVAELNETIRAHYIAVGVVDTTVEAQLSRGE 829
Cdd:TIGR02768 526 ALAAYRDHGHITIhDTREEAIEQVVADWKQDLREAnpaGSQIMLAHTRKDVRALNEAAREALIERGELGESILFQTARGE 605
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 830 KA-GVGDTILARKNQTFYDdetatstrINNGTLLTVTAIaENGSITARnTATGEELCLPADYvHDNVQLGYAATVHRAQG 908
Cdd:TIGR02768 606 RKfAAGDRIVFLENNRDLG--------VKNGMLGTVEEI-EDGRLVVQ-LDSGELVIIPQAE-YDALDHGYATTIHKSQG 674
|
410 420 430
....*....|....*....|....*....|....*..
gi 1958407961 909 STVDCTRAVIDYHVDRAGLYVALTRGKIANHIYAVIE 945
Cdd:TIGR02768 675 VTVDRAFVLASKSMDRHLAYVAMTRHRESVQLYAGKE 711
|
|
| PRK13889 |
PRK13889 |
conjugal transfer relaxase TraA; Provisional |
513-933 |
1.34e-30 |
|
conjugal transfer relaxase TraA; Provisional
Pssm-ID: 237546 [Multi-domain] Cd Length: 988 Bit Score: 131.35 E-value: 1.34e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 513 RDARADsELYTTQDILDTEDK---ALGALNEPVAAFAPSAAIDKALDeHEAESGFRLNAGQESMARYLlTCGTLAATGVG 589
Cdd:PRK13889 293 KDGRGE-DRFTTRAMIETEQRlhrAAELMAERERHAVSDADREAALA-RAEARGLVLSGEQADALAHV-TDGRDLGVVVG 369
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 590 PAGTGKTASMRLVANVWANQGRNVIGLAPSAQAAEVLSGDLGFDAFTIDKLTYTWRGnhptkpGHSLkdlpvsINAGDMI 669
Cdd:PRK13889 370 YAGTGKSAMLGVAREAWEAAGYEVRGAALSGIAAENLEGGSGIASRTIASLEHGWGQ------GRDL------LTSRDVL 437
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 670 IVDEAGMASTPNIGSLLEIAEEAGAVVRFIGDHKQLGAVENGGLFGAMVNAAGRTdnQLSEVVRFGGDSAQSAT-SLRL- 747
Cdd:PRK13889 438 VIDEAGMVGTRQLERVLSHAADAGAKVVLVGDPQQLQAIEAGAAFRSIHERHGGA--EIGEVRRQREDWQRDATrDLATg 515
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 748 REGDSstFDFYLERGWVNGG-----ARSDMLDKAAADYLAdiSSGKTSLLIAATNRDVAELNETIRAHYIAVGVVDTTVE 822
Cdd:PRK13889 516 RTGEA--LDAYEAHGMVHAAatreqARADLIDRWDRDRQA--APDRSRIILTHTNDEVRALNEAARERMRAAGDLGDDVR 591
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 823 AQLSRGEKA-GVGDTILARKNQtfyddetaTSTRINNGTLLTVTAIaENGSITARnTATGEELCLP-ADYVHdnVQLGYA 900
Cdd:PRK13889 592 VTVERGERSfASGDRVMFLQNE--------RGLGVKNGTLGTIEQV-SAQSMSVR-LDDGRSVAFDlKDYDR--IDHGYA 659
|
410 420 430
....*....|....*....|....*....|...
gi 1958407961 901 ATVHRAQGSTVDCTRAVIDYHVDRAGLYVALTR 933
Cdd:PRK13889 660 ATIHKAQGMTVDRTHVLATPGMDAHSSYVALSR 692
|
|
| DEXSc_RecD-like |
cd17933 |
DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1. ... |
589-722 |
6.62e-26 |
|
DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1.11.5, Exonuclease V) complex. It is the alpha chain of the complex and functions as a 3'-5' helicase. The RecBCD enzyme is both a helicase that unwinds, or separates the strands of DNA, and a nuclease that makes single-stranded nicks in DNA. RecD is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350691 [Multi-domain] Cd Length: 155 Bit Score: 105.33 E-value: 6.62e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 589 GPAGTGKTASMRLVANVWANQGRNVIGLAPSAQAAEVLSGDLGFDAFTIDKLTYTWRGNHPTKPGhslkdlPVSINAGDM 668
Cdd:cd17933 19 GGAGTGKTTTLKALLAALEAEGKRVVLAAPTGKAAKRLSESTGIEASTIHRLLGINPGGGGFYYN------EENPLDADL 92
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 1958407961 669 IIVDEAGMASTPNIGSLLEIAeEAGAVVRFIGDHKQLGAVENGGLFGAMVNAAG 722
Cdd:cd17933 93 LIVDEASMVDTRLMAALLSAI-PAGARLILVGDPDQLPSVGAGNVLRDLIASKG 145
|
|
| relax_trwC |
TIGR02686 |
conjugative relaxase domain, TrwC/TraI family; This domain is in the N-terminal (relaxase) ... |
167-399 |
6.64e-23 |
|
conjugative relaxase domain, TrwC/TraI family; This domain is in the N-terminal (relaxase) region of TrwC, a relaxase-helicase that acts in plasmid R388 conjugation. The relaxase domain has DNA cleavage and strand transfer activities. Plasmid transfer protein TraI is also a member of this domain family. Members of this family on bacterial chromosomes typically are found near other genes typical of conjugative plasmids and appear to mark integrated plasmids. [Mobile and extrachromosomal element functions, Plasmid functions]
Pssm-ID: 274258 [Multi-domain] Cd Length: 283 Bit Score: 100.61 E-value: 6.64e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 167 LKDNVRQSVSGFDLTFSPAKSVSVVWALSdeeTARRIEKLHHQAVKEAMAWAEDNALFTRVGKQG-REQVKTKGFVASEF 245
Cdd:TIGR02686 57 IEDRQSKHRPGFDLTFSAPKSVSILALVG---GDPRLIDAHDEAVKFTLEQLEKEAAAARVTQDGeIEFEKTGNLVIALF 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 246 KHYDTRAGDPDLHSHVLVSNKVQTEDGRW--LSID-------GYTLMKYHQSISHRYDSILNTLLsNEMGYTFTARDHGA 316
Cdd:TIGR02686 134 RHDTSRANDPQLHTHAVVANMTRRSDGKWrsLSSDkkgkhgfIEEIYKNQIYLGLLYRAKLANEL-KELGYQTRVYGKHG 212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 317 NkeptWEIEGVSESLMESFSKRRRGaqpvykrlVEEFVAARGTTpnsvevGRLWQQAILETRDAKREPESLTELRAGWKA 396
Cdd:TIGR02686 213 N----FEIDGVPEEVIEAFSKRRQQ--------IEEWVAERGWS------LAKSRDTAALDTRKKKTVHDREALREEWQQ 274
|
...
gi 1958407961 397 EVA 399
Cdd:TIGR02686 275 TAK 277
|
|
| PRK13709 |
PRK13709 |
conjugal transfer nickase/helicase TraI; Provisional |
177-494 |
9.02e-15 |
|
conjugal transfer nickase/helicase TraI; Provisional
Pssm-ID: 237478 [Multi-domain] Cd Length: 1747 Bit Score: 80.22 E-value: 9.02e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 177 GFDLTFSPAKSVSVVWALSDEetaRRIEKLHHQAVKEAMAWAEDNALfTRVGKQGR-EQVKTKGFVASEFKHYDTRAGDP 255
Cdd:PRK13709 78 GYDLTFSAPKSVSMMAMLGGD---KRLIEAHNQAVDFAVRQVEALAS-TRVMTDGQsETVLTGNLVMALFNHDTSRDQDP 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 256 DLHSHVLVSNKVQtEDGRW--LSID-----GY--TLMKYHQSISHRYDSILNTLLSnEMGY-TFTARDHGankepTWEIE 325
Cdd:PRK13709 154 QLHTHAVVANVTQ-HNGKWktLSSDkvgktGFieNVYANQIAFGKIYREALKEDVE-ALGYeTEVVGKHG-----MWEMK 226
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 326 GVSeslMESFSKRrrgaqpvyKRLVEEFVAARGtTPNSVEVgrlwqqAILETRDAKREPESLtELRAGWKAEVaaRDTG- 404
Cdd:PRK13709 227 GVP---VEAFSSR--------SQEIREAVGEDA-SLKSRDV------AALDTRKSKQHVDPE-VRMAEWMQTL--KETGf 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 405 --------AEELASINQLAADSARDERPlfDAEDHLSGLIDGVLDtvvrRRSYFRASHVATAAGGKLQgyrfASLAERDL 476
Cdd:PRK13709 286 dirayreaADQRAEIRTQAPGPASQDGP--DIQQAVTQAIAGLSD----RKVQFTYTDLLARTVGILP----PENGVIER 355
|
330
....*....|....*...
gi 1958407961 477 IHATVVEAIVRDKAISLN 494
Cdd:PRK13709 356 ARAGIDEAISREQLIPLD 373
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1136-1365 |
4.19e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 51.45 E-value: 4.19e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 1136 NLNRLNQEVLAeharfARSKVESLTWQEASITTRLHEDKDAAANEVKADYQQVRLDAARIRAYEQAMADHSAALRDEETA 1215
Cdd:COG4913 236 DLERAHEALED-----AREQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAE 310
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 1216 RADIEHQRLLAEDYTRPVTERAYDHDADGYGTYQQRIDQAHKRLEQAQQRRSLAQQAIEDTGCSLP--EAGLWE---EIC 1290
Cdd:COG4913 311 LERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPasAEEFAAlraEAA 390
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958407961 1291 YRADDHEEWDKRLREAEHHDSEHTHKLQQRLDTIRREKMDFADRADiAIRLRAEEIPHDVADHAGYIADEVNLLA 1365
Cdd:COG4913 391 ALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKS-NIPARLLALRDALAEALGLDEAELPFVG 464
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| TrwC |
pfam08751 |
TrwC relaxase; Relaxases are DNA strand transferases which function during the conjugative ... |
9-400 |
2.80e-78 |
|
TrwC relaxase; Relaxases are DNA strand transferases which function during the conjugative cell to cell DNA transfer. TrwC binds to the origin of transfer (oriT) and melts the double helix.
Pssm-ID: 430190 [Multi-domain] Cd Length: 279 Bit Score: 260.24 E-value: 2.80e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 9 SGTGYEYLLRSVAtndgptdapslskYYDAKGTPPGRWLGSGLAGLNTEnvvqgGEVTESQMAALYgEGLHPDADmkmse 88
Cdd:pfam08751 1 AGDAYAYYTRQDD-------------YYTEGGEPPGRWLGKGAAALGLS-----GEVTEEQFEALL-EGRHPDTG----- 56
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 89 gqkikdVQLGRPFanftndvpvlvalrdaerrhrqttgtlmgkqeraelvqdigreffieehgvepqsgreivnwvnglk 168
Cdd:pfam08751 57 ------ERLGRRR------------------------------------------------------------------- 63
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 169 DNVRQSVSGFDLTFSPAKSVSVVWALSDEEtarRIEKLHHQAVKEAMAWAEDNALFTRVGKQGR-EQVKTKGFVASEFKH 247
Cdd:pfam08751 64 PRGRKHRAGFDLTFSAPKSVSLLAAVGGDE---RIEAAHRAAVAEALAWLEKHAAQTRVGKDGGvEQVDTGGLVAAAFRH 140
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 248 YDTRAGDPDLHSHVLVSNKVQTEDGRWLSIDGYTLMKYHQSISHRYDSILNTLLSnEMGYTFTARdhgaNKEPTWEIEGV 327
Cdd:pfam08751 141 DTSRAGDPQLHTHVVVANVTQREDGKWRALDSRGLYKAQVAAGAVYRAELADELR-RLGYEIEER----GKRGVFEIAGV 215
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958407961 328 SESLMESFSKRRRGAQpvykRLVEEFVAARGTTPNSVEvgrlwQQAILETRDAKREPESLTELRAGWKAEVAA 400
Cdd:pfam08751 216 PEELIEAFSKRRAQIE----AELAELGATHGRAPPAAR-----QIAALETRPAKHEPRSLAELRARWREEAAE 279
|
|
| RecD |
COG0507 |
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) ... |
487-942 |
1.79e-69 |
|
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];
Pssm-ID: 440273 [Multi-domain] Cd Length: 514 Bit Score: 243.35 E-value: 1.79e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 487 RDKAISLNDFDVLELPEALKNSAGKARDARADSELYTTQdILDTEDKALGALNEPVAAFAPSAAIDKALDEHEAESGFRL 566
Cdd:COG0507 47 LEDLAAARLLGVAEDIEAALAALVESGPLVLDGRRYLTR-LLEAEQRLARRLRRLARPALDEADVEAALAALEPRAGITL 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 567 NAGQESMARYLLTCGTLAAtGVGPAGTGKTASMRLVANVWANQGRNVIGLAPSAQAAEVLSGDLGFDAFTIDKLTYtWRG 646
Cdd:COG0507 126 SDEQREAVALALTTRRVSV-LTGGAGTGKTTTLRALLAALEALGLRVALAAPTGKAAKRLSESTGIEARTIHRLLG-LRP 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 647 NHPTKPGHSLKDLpvsiNAGDMIIVDEAGMASTPNIGSLLEIAEEAGAVVRFIGDHKQLGAVENGGLFGAMVNAAGRTDN 726
Cdd:COG0507 204 DSGRFRHNRDNPL----TPADLLVVDEASMVDTRLMAALLEALPRAGARLILVGDPDQLPSVGAGAVLRDLIESGTVPVV 279
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 727 QLSEVVRFGGDSAQSATSLRLREGDSSTF--DFYLERGWVNGGARSDMLDKAAADYLADISSGKTSLLIAATNRDVAELN 804
Cdd:COG0507 280 ELTEVYRQADDSRIIELAHAIREGDAPEAlnARYADVVFVEAEDAEEAAEAIVELYADRPAGGEDIQVLAPTNAGVDALN 359
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 805 ETIRAHYIAVGVVDTTVEAqlSRGEKAGVGDTILARKNQtfYDDetatstRINNGTLLTVTAIAEN-GSITARNtaTGEE 883
Cdd:COG0507 360 QAIREALNPAGELERELAE--DGELELYVGDRVMFTRND--YDL------GVFNGDIGTVLSIDEDeGRLTVRF--DGRE 427
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958407961 884 LCLPADYVHDNVQLGYAATVHRAQGSTVDCTRAVIDYH----VDRAGLYVALTRGKIANHIYA 942
Cdd:COG0507 428 IVTYDPSELDQLELAYAITVHKSQGSTFDRVILVLPSEhsplLSRELLYTALTRARELLTLVG 490
|
|
| AAA_30 |
pfam13604 |
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ... |
565-767 |
2.52e-57 |
|
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. There is a Walker A and Walker B.
Pssm-ID: 433343 [Multi-domain] Cd Length: 191 Bit Score: 196.63 E-value: 2.52e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 565 RLNAGQESMARYLLTCGTLAATGVGPAGTGKTASMRLVANVWANQGRNVIGLAPSAQAAEVLSGDLGFDAFTIDKLTYTW 644
Cdd:pfam13604 1 TLNAEQAAAVRALLTSGDRVAVLVGPAGTGKTTALKALREAWEAAGYRVIGLAPTGRAAKVLGEELGIPADTIAKLLHRL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 645 RGnhptkpghslkdlPVSINAGDMIIVDEAGMASTPNIGSLLEIAEEAGAVVRFIGDHKQLGAVENGGLFGAMVnAAGRT 724
Cdd:pfam13604 81 GG-------------RAGLDPGTLLIVDEAGMVGTRQMARLLKLAEDAGARVILVGDPRQLPSVEAGGAFRDLL-AAGIG 146
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1958407961 725 DNQLSEVVRFgGDSAQSATSLRLREGD-SSTFDFYLERGWVNGG 767
Cdd:pfam13604 147 TAELTEIVRQ-RDPWQRAASLALRDGDpAEALDALADRGRIHEG 189
|
|
| MobF |
NF041492 |
MobF family relaxase; |
1-397 |
4.04e-55 |
|
MobF family relaxase;
Pssm-ID: 469380 [Multi-domain] Cd Length: 288 Bit Score: 194.06 E-value: 4.04e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 1 MMTLRVVNS-GTGYEYLLRSVATNdgptdapslskYY-DAKGTPPGRWLGSGLAGLNtenvVQGGEVTESQMAALYgEGL 78
Cdd:NF041492 1 MLSIARIGSaGGAARYYTEKDLDN-----------YYsEDGGTPAGRWFGKGAEALG----LSGGAVDGERFKALL-DGR 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 79 HPDadmkmseGQKIKDVQLGrpfanftndvpvlvalrdaERRHRqttgtlmgkqeraelvqdigreffieehgvepqsgr 158
Cdd:NF041492 65 LPD-------GERLRRRRKG-------------------AGRHR------------------------------------ 82
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 159 eivnwvnglkdnvrqsvSGFDLTFSPAKSVSVVWALSDEetaRRIEKLHHQAVKEAMAWAEDNALFTRVGKQGR---EQV 235
Cdd:NF041492 83 -----------------PGYDLTFSAPKSVSLLALVGGD---KRLIEAHDEAVKEALEYLEERLAQTRVTVDGKgrtSLE 142
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 236 KTKGFVASEFKHYDTRAGDPDLHSHVLVSNKVQTEDGRWLSIDGYTLMKYHQSISHRYDSILNTLLSnEMGYTFTARDHG 315
Cdd:NF041492 143 KTGNLVAALFRHDTSRAGDPQLHTHAVVMNMTQRPDGKWRSLDNEELYKNQKALGAIYQAELAEELQ-ALGYEIRETKNG 221
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 316 ankepTWEIEGVSESLMESFSKRRRGaqpvykrlVEEFVAARGTTPNSVEVGrlwQQAILETRDAKREPESLTELRAGWK 395
Cdd:NF041492 222 -----QFEIAGVPREQIEAFSKRSQQ--------IEEWLGENPATLASAALR---QIAALDTRKAKEADVDPEELEAEWR 285
|
..
gi 1958407961 396 AE 397
Cdd:NF041492 286 EE 287
|
|
| TraA_Ti |
TIGR02768 |
Ti-type conjugative transfer relaxase TraA; This protein contains domains distinctive of a ... |
518-945 |
3.96e-48 |
|
Ti-type conjugative transfer relaxase TraA; This protein contains domains distinctive of a single strand exonuclease (N-terminus, MobA/MobL, pfam03389) as well as a helicase domain (central region, homologous to the corresponding region of the F-type relaxase TraI, TIGR02760). This protein likely fills the same role as TraI(F), nicking (at the oriT site) and unwinding the coiled plasmid prior to conjugative transfer.
Pssm-ID: 274289 [Multi-domain] Cd Length: 744 Bit Score: 185.40 E-value: 3.96e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 518 DSELYTTQDILDTE---DKALGALNEPVAAFAPSAAIDKALDEHeaesgFRLNAGQESMARYLLTCGTLAATgVGPAGTG 594
Cdd:TIGR02768 307 EPARFSTREMIRLEaqmARSAEALSQSQGHGVSPPIVDAAIDQH-----YRLSEEQYEAVRHVTGSGDIAVV-VGRAGTG 380
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 595 KTASMRLVANVWANQGRNVIGLAPSAQAAEVLSGDLGFDAFTIDKLTYTW-RGnhptkpghslKDLpvsINAGDMIIVDE 673
Cdd:TIGR02768 381 KSTMLKAAREAWEAAGYRVIGAALSGKAAEGLQAESGIESRTLASLEYAWaNG----------RDL---LSDKDVLVIDE 447
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 674 AGMASTPNIGSLLEIAEEAGAVVRFIGDHKQLGAVENGGLFGAMVNAAGRTdnQLSEVVRFGGDSAQSATSLRLREGDSS 753
Cdd:TIGR02768 448 AGMVGSRQMARVLKEAEEAGAKVVLVGDPEQLQPIEAGAAFRAIAERIGYA--ELETIRRQREAWARQASLELARGDVEK 525
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 754 TFDFYLERGWVNG-GARSDMLDKAAADYLADISSG---KTSLLIAATNRDVAELNETIRAHYIAVGVVDTTVEAQLSRGE 829
Cdd:TIGR02768 526 ALAAYRDHGHITIhDTREEAIEQVVADWKQDLREAnpaGSQIMLAHTRKDVRALNEAAREALIERGELGESILFQTARGE 605
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 830 KA-GVGDTILARKNQTFYDdetatstrINNGTLLTVTAIaENGSITARnTATGEELCLPADYvHDNVQLGYAATVHRAQG 908
Cdd:TIGR02768 606 RKfAAGDRIVFLENNRDLG--------VKNGMLGTVEEI-EDGRLVVQ-LDSGELVIIPQAE-YDALDHGYATTIHKSQG 674
|
410 420 430
....*....|....*....|....*....|....*..
gi 1958407961 909 STVDCTRAVIDYHVDRAGLYVALTRGKIANHIYAVIE 945
Cdd:TIGR02768 675 VTVDRAFVLASKSMDRHLAYVAMTRHRESVQLYAGKE 711
|
|
| TraI_TIGR |
TIGR02760 |
conjugative transfer relaxase protein TraI; This protein is a component of the relaxosome ... |
169-830 |
2.31e-37 |
|
conjugative transfer relaxase protein TraI; This protein is a component of the relaxosome complex. In the process of conjugative plasmid transfer the realaxosome binds to the plasmid at the oriT (origin of transfer) site. The relaxase protein TraI mediates the single-strand nicking and ATP-dependent unwinding (relaxation, helicase activity) of the plasmid molecule. These two activities reside in separate domains of the protein.
Pssm-ID: 274285 [Multi-domain] Cd Length: 1960 Bit Score: 154.29 E-value: 2.31e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 169 DNVRQSVSGFDLTFSPAKSVSVVWALSDEEtarRIEKLHHQAVKEAMAWAEDNALFTRVGKQG-REQVKTKGFVASEFKH 247
Cdd:TIGR02760 75 KGGIHHRPGFDLTFSAPKSVSILALVGGDK---RLIEAHDKAVKIAVSEMEKDAAQARQTVDGkTEFINTRNLVFAMFRH 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 248 YDTRAGDPDLHSHVLVSNKVQTEDGRWLS-----------IDGYT--LMKYHQSISHRYDSILNTLlSNEMGYTFTARDH 314
Cdd:TIGR02760 152 KTSRENDPQLHTHAVVQNMTHDSDGKWRSlasdmkgqkgvIEGFRerIYNHQIYYGLLYRSKLAKK-VEELGYQTASVGK 230
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 315 GankepTWEIEGVSESLMESFSKRRRGaqpvykrlVEEFVAARGT-TPNSVEVgrlwqqAILETRDAKREPESLTeLRAG 393
Cdd:TIGR02760 231 G-----QFEIQGVPEQVLTAFSKRRQQ--------IDELVDEKGWsSAKARDI------AALDTRKDKTYIDDET-LMEK 290
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 394 WKAEVaaRDTGAEelasINQLAADSARDERplfdaedhlsglidgvldtvVRRRSYFRASHVATAAGGKL---QGYRFAS 470
Cdd:TIGR02760 291 WQQEC--KDMGFD----PHALVASSYKPEN--------------------IVARFYGPSQIDAQHAVEVAiahLSQYSTQ 344
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 471 LAERDLIHATVVEAIVRDKAISLNDFDvLELPEALKNSA--GKARDaradSELYTTQDILDTEDKALGALNEPVAAFaps 548
Cdd:TIGR02760 345 FEYEKLIEEAAKYFTAGNKIIDEIDIK-KAIDELIANGQliPLFTQ----KGLFTTQTMLTNEKELIARTEGGKGAL--- 416
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 549 aaidKALDEHEAESGFRLNAGQESMARYLLTCGTLAATGVGPAGTGKTASMRLVANVWANQGRNVIGLAPSAQAAEVLSG 628
Cdd:TIGR02760 417 ----RVIVSKQKLSEFALSPSNKDAVSTLFTSTKRFIIINGFGGTGSTEIAQLLLHLASEQGYEIQIITAGSLSAQELRQ 492
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 629 DLGFDAFTIdkltYTWRGN------HPTKPGHSLKDLPVSinAGDMIIVDEAGMASTPNIGSLLEIAEEAGAVVRFIGDH 702
Cdd:TIGR02760 493 KIPRLASTF----ITWVKNlfnddqDHTVQGLLDKSSPFS--NKDIFVVDEANKLSNNELLKLIDKAEQHNSKLILLNDS 566
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 703 KQLGAVENGGLFGAMVNAAGRTDNQLsevvrfggDSAQSATSLRLREGDsstfdfylergwvnggaRSDMLDKAAADYLA 782
Cdd:TIGR02760 567 AQRQGMSAGSAIDLLKEGGVTTYAWV--------DTKQQKASVEISEAV-----------------DKLRVDYIASAWLD 621
|
650 660 670 680
....*....|....*....|....*....|....*....|....*...
gi 1958407961 783 DISSGKTSLLIAATNRDVAELNETIRAHYIAVGvvdttveaQLSRGEK 830
Cdd:TIGR02760 622 LTPDRQNSQVLATTHREQQDLTQIIRNALKQEG--------QLSRQEV 661
|
|
| PRK13889 |
PRK13889 |
conjugal transfer relaxase TraA; Provisional |
513-933 |
1.34e-30 |
|
conjugal transfer relaxase TraA; Provisional
Pssm-ID: 237546 [Multi-domain] Cd Length: 988 Bit Score: 131.35 E-value: 1.34e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 513 RDARADsELYTTQDILDTEDK---ALGALNEPVAAFAPSAAIDKALDeHEAESGFRLNAGQESMARYLlTCGTLAATGVG 589
Cdd:PRK13889 293 KDGRGE-DRFTTRAMIETEQRlhrAAELMAERERHAVSDADREAALA-RAEARGLVLSGEQADALAHV-TDGRDLGVVVG 369
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 590 PAGTGKTASMRLVANVWANQGRNVIGLAPSAQAAEVLSGDLGFDAFTIDKLTYTWRGnhptkpGHSLkdlpvsINAGDMI 669
Cdd:PRK13889 370 YAGTGKSAMLGVAREAWEAAGYEVRGAALSGIAAENLEGGSGIASRTIASLEHGWGQ------GRDL------LTSRDVL 437
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 670 IVDEAGMASTPNIGSLLEIAEEAGAVVRFIGDHKQLGAVENGGLFGAMVNAAGRTdnQLSEVVRFGGDSAQSAT-SLRL- 747
Cdd:PRK13889 438 VIDEAGMVGTRQLERVLSHAADAGAKVVLVGDPQQLQAIEAGAAFRSIHERHGGA--EIGEVRRQREDWQRDATrDLATg 515
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 748 REGDSstFDFYLERGWVNGG-----ARSDMLDKAAADYLAdiSSGKTSLLIAATNRDVAELNETIRAHYIAVGVVDTTVE 822
Cdd:PRK13889 516 RTGEA--LDAYEAHGMVHAAatreqARADLIDRWDRDRQA--APDRSRIILTHTNDEVRALNEAARERMRAAGDLGDDVR 591
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 823 AQLSRGEKA-GVGDTILARKNQtfyddetaTSTRINNGTLLTVTAIaENGSITARnTATGEELCLP-ADYVHdnVQLGYA 900
Cdd:PRK13889 592 VTVERGERSfASGDRVMFLQNE--------RGLGVKNGTLGTIEQV-SAQSMSVR-LDDGRSVAFDlKDYDR--IDHGYA 659
|
410 420 430
....*....|....*....|....*....|...
gi 1958407961 901 ATVHRAQGSTVDCTRAVIDYHVDRAGLYVALTR 933
Cdd:PRK13889 660 ATIHKAQGMTVDRTHVLATPGMDAHSSYVALSR 692
|
|
| DEXSc_RecD-like |
cd17933 |
DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1. ... |
589-722 |
6.62e-26 |
|
DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1.11.5, Exonuclease V) complex. It is the alpha chain of the complex and functions as a 3'-5' helicase. The RecBCD enzyme is both a helicase that unwinds, or separates the strands of DNA, and a nuclease that makes single-stranded nicks in DNA. RecD is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350691 [Multi-domain] Cd Length: 155 Bit Score: 105.33 E-value: 6.62e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 589 GPAGTGKTASMRLVANVWANQGRNVIGLAPSAQAAEVLSGDLGFDAFTIDKLTYTWRGNHPTKPGhslkdlPVSINAGDM 668
Cdd:cd17933 19 GGAGTGKTTTLKALLAALEAEGKRVVLAAPTGKAAKRLSESTGIEASTIHRLLGINPGGGGFYYN------EENPLDADL 92
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 1958407961 669 IIVDEAGMASTPNIGSLLEIAeEAGAVVRFIGDHKQLGAVENGGLFGAMVNAAG 722
Cdd:cd17933 93 LIVDEASMVDTRLMAALLSAI-PAGARLILVGDPDQLPSVGAGNVLRDLIASKG 145
|
|
| PRK13826 |
PRK13826 |
Dtr system oriT relaxase; Provisional |
549-933 |
1.53e-25 |
|
Dtr system oriT relaxase; Provisional
Pssm-ID: 237524 [Multi-domain] Cd Length: 1102 Bit Score: 115.26 E-value: 1.53e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 549 AAIDKALDEHEaesgfRLNAGQESMARYLLTCGTLAATgVGPAGTGKTASMRLVANVWANQGRNVIGLAPSAQAAEVLSG 628
Cdd:PRK13826 370 AVLAATFARHA-----RLSDEQKTAIEHVAGPARIAAV-VGRAGAGKTTMMKAAREAWEAAGYRVVGGALAGKAAEGLEK 443
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 629 DLGFDAFTIDKLTYTWrgnhptKPGHSLKDlpvsinAGDMIIVDEAGMASTPNIGSLLEIAEEAGAVVRFIGDHKQLGAV 708
Cdd:PRK13826 444 EAGIQSRTLSSWELRW------NQGRDQLD------NKTVFVLDEAGMVASRQMALFVEAVTRAGAKLVLVGDPEQLQPI 511
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 709 ENGGLFGAMVNAAGRTdnQLSEVVRFGGDSAQSAtSLRLREGD-SSTFDFYLERGWVNGGA-RSDMLDKAAADYLADISS 786
Cdd:PRK13826 512 EAGAAFRAIADRIGYA--ELETIYRQREQWMRDA-SLDLARGNvGKALDAYRANGRVIGSRlKAEAVESLIADWNRDYDP 588
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 787 GKTSLLIAATNRDVAELNETIRAHYIAVGVVDTTVEAQLSRGEKA-GVGDTILARKNQTfyddetatSTRINNGTLLTVT 865
Cdd:PRK13826 589 TKTTLILAHLRRDVRMLNEMARAKLVERGIVGEGHAFRTADGERRfAAGDQIVFLKNEG--------SLGVKNGMIGKVV 660
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958407961 866 AIAENGSITARNTATGEELCLPADYVHDNVQLGYAATVHRAQGSTVDCTRAVIDYHVDRAGLYVALTR 933
Cdd:PRK13826 661 EAAPNRIVAEIGEGEHRRQVTVEQRFYNNLDHGYATTIHKSQGATVDRVKVLASLSLDRHLTYVAMTR 728
|
|
| relax_trwC |
TIGR02686 |
conjugative relaxase domain, TrwC/TraI family; This domain is in the N-terminal (relaxase) ... |
167-399 |
6.64e-23 |
|
conjugative relaxase domain, TrwC/TraI family; This domain is in the N-terminal (relaxase) region of TrwC, a relaxase-helicase that acts in plasmid R388 conjugation. The relaxase domain has DNA cleavage and strand transfer activities. Plasmid transfer protein TraI is also a member of this domain family. Members of this family on bacterial chromosomes typically are found near other genes typical of conjugative plasmids and appear to mark integrated plasmids. [Mobile and extrachromosomal element functions, Plasmid functions]
Pssm-ID: 274258 [Multi-domain] Cd Length: 283 Bit Score: 100.61 E-value: 6.64e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 167 LKDNVRQSVSGFDLTFSPAKSVSVVWALSdeeTARRIEKLHHQAVKEAMAWAEDNALFTRVGKQG-REQVKTKGFVASEF 245
Cdd:TIGR02686 57 IEDRQSKHRPGFDLTFSAPKSVSILALVG---GDPRLIDAHDEAVKFTLEQLEKEAAAARVTQDGeIEFEKTGNLVIALF 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 246 KHYDTRAGDPDLHSHVLVSNKVQTEDGRW--LSID-------GYTLMKYHQSISHRYDSILNTLLsNEMGYTFTARDHGA 316
Cdd:TIGR02686 134 RHDTSRANDPQLHTHAVVANMTRRSDGKWrsLSSDkkgkhgfIEEIYKNQIYLGLLYRAKLANEL-KELGYQTRVYGKHG 212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 317 NkeptWEIEGVSESLMESFSKRRRGaqpvykrlVEEFVAARGTTpnsvevGRLWQQAILETRDAKREPESLTELRAGWKA 396
Cdd:TIGR02686 213 N----FEIDGVPEEVIEAFSKRRQQ--------IEEWVAERGWS------LAKSRDTAALDTRKKKTVHDREALREEWQQ 274
|
...
gi 1958407961 397 EVA 399
Cdd:TIGR02686 275 TAK 277
|
|
| PRK13709 |
PRK13709 |
conjugal transfer nickase/helicase TraI; Provisional |
177-494 |
9.02e-15 |
|
conjugal transfer nickase/helicase TraI; Provisional
Pssm-ID: 237478 [Multi-domain] Cd Length: 1747 Bit Score: 80.22 E-value: 9.02e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 177 GFDLTFSPAKSVSVVWALSDEetaRRIEKLHHQAVKEAMAWAEDNALfTRVGKQGR-EQVKTKGFVASEFKHYDTRAGDP 255
Cdd:PRK13709 78 GYDLTFSAPKSVSMMAMLGGD---KRLIEAHNQAVDFAVRQVEALAS-TRVMTDGQsETVLTGNLVMALFNHDTSRDQDP 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 256 DLHSHVLVSNKVQtEDGRW--LSID-----GY--TLMKYHQSISHRYDSILNTLLSnEMGY-TFTARDHGankepTWEIE 325
Cdd:PRK13709 154 QLHTHAVVANVTQ-HNGKWktLSSDkvgktGFieNVYANQIAFGKIYREALKEDVE-ALGYeTEVVGKHG-----MWEMK 226
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 326 GVSeslMESFSKRrrgaqpvyKRLVEEFVAARGtTPNSVEVgrlwqqAILETRDAKREPESLtELRAGWKAEVaaRDTG- 404
Cdd:PRK13709 227 GVP---VEAFSSR--------SQEIREAVGEDA-SLKSRDV------AALDTRKSKQHVDPE-VRMAEWMQTL--KETGf 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 405 --------AEELASINQLAADSARDERPlfDAEDHLSGLIDGVLDtvvrRRSYFRASHVATAAGGKLQgyrfASLAERDL 476
Cdd:PRK13709 286 dirayreaADQRAEIRTQAPGPASQDGP--DIQQAVTQAIAGLSD----RKVQFTYTDLLARTVGILP----PENGVIER 355
|
330
....*....|....*...
gi 1958407961 477 IHATVVEAIVRDKAISLN 494
Cdd:PRK13709 356 ARAGIDEAISREQLIPLD 373
|
|
| SF1_C_RecD |
cd18809 |
C-terminal helicase domain of RecD family helicases; RecD is a member of the RecBCD (EC 3.1.11. ... |
897-942 |
1.46e-10 |
|
C-terminal helicase domain of RecD family helicases; RecD is a member of the RecBCD (EC 3.1.11.5, Exonuclease V) complex. It is the alpha chain of the complex and functions as a 3'-5' helicase. The RecBCD enzyme is both a helicase that unwinds, or separates the strands of DNA, and a nuclease that makes single-stranded nicks in DNA. RecD family helicases are DEAD-like helicases belonging to superfamily (SF)1, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF2 helicases, SF1 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350196 [Multi-domain] Cd Length: 80 Bit Score: 58.73 E-value: 1.46e-10
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 1958407961 897 LGYAATVHRAQGSTVDCTRAVIDYH---VDRAGLYVALTRGKIANHIYA 942
Cdd:cd18809 32 QAYAMTIHKSQGSEFDRVIVVLPTShpmLSRGLLYTALTRARKLLTLVG 80
|
|
| AAA_19 |
pfam13245 |
AAA domain; |
589-705 |
6.27e-08 |
|
AAA domain;
Pssm-ID: 433059 [Multi-domain] Cd Length: 136 Bit Score: 52.99 E-value: 6.27e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 589 GPAGTGKTASMRLVANVWANQG---RNVIGLAPSAQAAEVLSGDLGFDAFTIDKLTytwrGNHPTKPGHSLKDlPVSINA 665
Cdd:pfam13245 18 GGPGTGKTTTIRHIVALLVALGgvsFPILLAAPTGRAAKRLSERTGLPASTIHRLL----GFDDLEAGGFLRD-EEEPLD 92
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 1958407961 666 GDMIIVDEAGMASTPNIGSLLEiAEEAGAVVRFIGDHKQL 705
Cdd:pfam13245 93 GDLLIVDEFSMVDLPLAYRLLK-ALPDGAQLLLVGDPDQL 131
|
|
| TraI_TIGR |
TIGR02760 |
conjugative transfer relaxase protein TraI; This protein is a component of the relaxosome ... |
481-711 |
1.06e-07 |
|
conjugative transfer relaxase protein TraI; This protein is a component of the relaxosome complex. In the process of conjugative plasmid transfer the realaxosome binds to the plasmid at the oriT (origin of transfer) site. The relaxase protein TraI mediates the single-strand nicking and ATP-dependent unwinding (relaxation, helicase activity) of the plasmid molecule. These two activities reside in separate domains of the protein.
Pssm-ID: 274285 [Multi-domain] Cd Length: 1960 Bit Score: 57.22 E-value: 1.06e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 481 VVEAIVRdkAISLNDFDVL--ELPEALKNSAGKARDARA---DSELYTTQDILDTEDKALGAL---NEPVAAFAPSAAID 552
Cdd:TIGR02760 934 VTEAYVF--AFEETGFAIKaaEIAAALKNRPKLYRLLSAeygDGTRWTTRAALRTETSILLHIlpgKETVTPLATRAQVF 1011
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 553 KALDEHEaesgfRLNAGQESMARYLLTCGTLAATGVGPAGTGKT----ASMRLVANVWANQGRNVIGLAPSAQAAEVLSG 628
Cdd:TIGR02760 1012 LNLELLE-----RLTHGQKQAIHLIISTKDRFVAVQGLAGVGKTtmleSRYKPVLQAFESEQLQVIGLAPTHEAVGELKS 1086
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 629 DlGFDAFTIDKLtytwrgnhptkpghsLKDLPVSINAGD-----MIIVDEAGMASTPNIGSLLEIAEEAGAVVRFIGDHK 703
Cdd:TIGR02760 1087 A-GVQAQTLDSF---------------LTDISLYRNSGGdfrntLFILDESSMVSNFQLTHATELVQKSGSRAVSLGDIA 1150
|
....*...
gi 1958407961 704 QLGAVENG 711
Cdd:TIGR02760 1151 QLQSLAAG 1158
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1136-1365 |
4.19e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 51.45 E-value: 4.19e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 1136 NLNRLNQEVLAeharfARSKVESLTWQEASITTRLHEDKDAAANEVKADYQQVRLDAARIRAYEQAMADHSAALRDEETA 1215
Cdd:COG4913 236 DLERAHEALED-----AREQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAE 310
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 1216 RADIEHQRLLAEDYTRPVTERAYDHDADGYGTYQQRIDQAHKRLEQAQQRRSLAQQAIEDTGCSLP--EAGLWE---EIC 1290
Cdd:COG4913 311 LERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPasAEEFAAlraEAA 390
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958407961 1291 YRADDHEEWDKRLREAEHHDSEHTHKLQQRLDTIRREKMDFADRADiAIRLRAEEIPHDVADHAGYIADEVNLLA 1365
Cdd:COG4913 391 ALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKS-NIPARLLALRDALAEALGLDEAELPFVG 464
|
|
| DEXXQc_Helz-like |
cd18038 |
DEXXQ/H-box helicase domain of Helz-like helicase; This subfamily contains HELZ, Mov10L1, and ... |
589-708 |
1.30e-05 |
|
DEXXQ/H-box helicase domain of Helz-like helicase; This subfamily contains HELZ, Mov10L1, and similar proteins. Helicase with zinc finger (HELZ) acts as a helicase that plays a role in RNA metabolism during development. Moloney leukemia virus 10-like protein 1 (Mov10L1) binds Piwi-interacting RNA (piRNA) precursors to initiate piRNA processing. All are members of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350796 [Multi-domain] Cd Length: 229 Bit Score: 48.00 E-value: 1.30e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 589 GPAGTGKTAS-MRLVANVWANQGRNVI-GLAPSAQAAEVLSGDL------------------GFDAFTIDKLTYTWRGN- 647
Cdd:cd18038 27 GPPGTGKTVTlVEAILQVLRQPPEARIlVCAPSNSAADLLAERLlnalvtkreilrlnapsrDRASVPPELLPYCNSKAe 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 648 ----HPTKP---------------GHsLKDLPVSINAGDMIIVDEAGMASTPNIGSLLEIAEEAGAVVRFIGDHKQLGAV 708
Cdd:cd18038 107 gtfrLPSLEelkkyrivvctlmtaGR-LVQAGVPNGHFTHIFIDEAGQATEPEALIPLSELASKNTQIVLAGDPKQLGPV 185
|
|
| DEXXQc_Upf1-like |
cd17934 |
DEXXQ-box helicase domain of Upf1-like helicase; The Upf1-like helicase family includes UPF1, ... |
661-708 |
7.69e-05 |
|
DEXXQ-box helicase domain of Upf1-like helicase; The Upf1-like helicase family includes UPF1, HELZ, Mov10L1, Aquarius, IGHMBP2 (SMUBP2), coronavirus Nsp13, and similar proteins. They belong to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438708 [Multi-domain] Cd Length: 121 Bit Score: 43.76 E-value: 7.69e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 1958407961 661 VSINAGDMIIVDEAGMASTPNIgslleiaeeAGAVVR-----FIGDHKQLGAV 708
Cdd:cd17934 40 VAVDNVDVVIIDEASQITEPEL---------LIALIRakkvvLVGDPKQLPPV 83
|
|
| SF1_C |
cd18786 |
C-terminal helicase domain of superfamily 1 DEAD/H-box helicases; Superfamily (SF)1 family ... |
893-942 |
1.39e-04 |
|
C-terminal helicase domain of superfamily 1 DEAD/H-box helicases; Superfamily (SF)1 family members include UvrD/Rep, Pif1-like, and Upf-1-like proteins. Similar to SF2 helicases, they do not form toroidal, predominantly hexameric structures like SF3-6. SF1 helicases are a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Their helicase core is surrounded by C- and N-terminal domains with specific functions such as nucleases, RNA or DNA binding domains, or domains engaged in protein-protein interactions. The core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350173 [Multi-domain] Cd Length: 89 Bit Score: 42.04 E-value: 1.39e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 1958407961 893 DNVQLGYAATVHRAQGSTVDctraVIDYHVDRAG------LYVALTRGKIANHIYA 942
Cdd:cd18786 38 FDLQLVGAITIDSSQGLTFD----VVTLYLPTANsltprrLYVALTRARKRLVIYD 89
|
|
| DExxQc_SF1-N |
cd17914 |
DEXQ-box helicase domain of superfamily 1 helicase; The superfamily (SF)1 family members ... |
588-722 |
2.12e-04 |
|
DEXQ-box helicase domain of superfamily 1 helicase; The superfamily (SF)1 family members include UvrD/Rep, Pif1-like, and Upf-1-like proteins. Like SF2, they do not form toroidal, predominantly hexameric structures like SF3-6. Their helicase core is surrounded by C and N-terminal domains with specific functions such as nucleases, RNA or DNA binding domains or domains engaged in protein-protein interactions. SF1 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438706 [Multi-domain] Cd Length: 121 Bit Score: 42.47 E-value: 2.12e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 588 VGPAGTGKT-ASMRLVANVWANQGrnviglapsaqaaevlsgdlgFDAFTIDKLTYTwrgnhptkpGHSLKDLpvsinag 666
Cdd:cd17914 5 QGPPGTGKTrVLVKIVAALMQNKN---------------------GEPGRILLVTPT---------NKAAAQL------- 47
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 1958407961 667 DMIIVDEAGMASTPNIGSLLEIAEEAGAVVrFIGDHKQLGAVENGGLFGAMVNAAG 722
Cdd:cd17914 48 DNILVDEAAQILEPETSRLIDLALDQGRVI-LVGDHDQLGPVWRGAVLAKICNEQS 102
|
|
| UvrD_C_2 |
pfam13538 |
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety ... |
897-935 |
1.50e-03 |
|
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety of helicase enzymes. This domain has a AAA-like structural fold.
Pssm-ID: 463913 [Multi-domain] Cd Length: 52 Bit Score: 37.94 E-value: 1.50e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 1958407961 897 LGYAATVHRAQGSTVDCTRAVIDYHVDRAG-------LYVALTRGK 935
Cdd:pfam13538 1 LAYALTVHKAQGSEFPAVFLVDPDLTAHYHsmlrrrlLYTAVTRAR 46
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
588-707 |
1.97e-03 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 40.21 E-value: 1.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 588 VGPAGTGKTASMRLVANVWANQGRNVIGLapsaQAAEVLSGDLGFDAFTIDKLTytwrgnhptkpghsLKDLPVSINAGD 667
Cdd:cd00009 25 YGPPGTGKTTLARAIANELFRPGAPFLYL----NASDLLEGLVVAELFGHFLVR--------------LLFELAEKAKPG 86
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 1958407961 668 MIIVDEAGMASTPNIGSLLEIAEEAGAVVRFIGDHKQLGA 707
Cdd:cd00009 87 VLFIDEIDSLSRGAQNALLRVLETLNDLRIDRENVRVIGA 126
|
|
| EmrA |
COG1566 |
Multidrug resistance efflux pump EmrA [Defense mechanisms]; |
1175-1274 |
4.06e-03 |
|
Multidrug resistance efflux pump EmrA [Defense mechanisms];
Pssm-ID: 441174 [Multi-domain] Cd Length: 331 Bit Score: 41.19 E-value: 4.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 1175 DAAANEVKADYQQVRLDAARIRAYEQAMADHSAALRDEETARADIEhqrLLAEDYTRpvTERAYdhdADGYGTyQQRIDQ 1254
Cdd:COG1566 82 QAALAQAEAQLAAAEAQLARLEAELGAEAEIAAAEAQLAAAQAQLD---LAQRELER--YQALY---KKGAVS-QQELDE 152
|
90 100
....*....|....*....|
gi 1958407961 1255 AHKRLEQAQQRRSLAQQAIE 1274
Cdd:COG1566 153 ARAALDAAQAQLEAAQAQLA 172
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1137-1463 |
4.67e-03 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 41.46 E-value: 4.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 1137 LNRLNQEVLAEHARFARSKVESLTWQEASITTRLhEDKDAAANEVKADYQQVRLDAARIR-AYEQAMADHSAALRDEETA 1215
Cdd:COG1196 222 LKELEAELLLLKLRELEAELEELEAELEELEAEL-EELEAELAELEAELEELRLELEELElELEEAQAEEYELLAELARL 300
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 1216 RADIEHQrllaedytrpvteraydhdadgygtyQQRIDQAHKRLEQAQQRRSLAQQAIEDTGCSLPEAGlwEEICYRADD 1295
Cdd:COG1196 301 EQDIARL--------------------------EERRRELEERLEELEEELAELEEELEELEEELEELE--EELEEAEEE 352
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 1296 HEEWDKRLREAEHHDSEHTHKLQQRLDTIRREKMDFADRADIAIRLRAEEIpHDVADHAGYIADEVNLLAAQRTYELRRL 1375
Cdd:COG1196 353 LEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLE-ELEEAEEALLERLERLEEELEELEEALA 431
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 1376 GVDEP------AQEAIRDMVAETIAAAYEQDNDDTHHDEQNTAVQNKAEEEQPAPETTTADESADNTQGEDTGGLNEGAR 1449
Cdd:COG1196 432 ELEEEeeeeeeALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVK 511
|
330
....*....|....
gi 1958407961 1450 ASLDFLASLGLGGE 1463
Cdd:COG1196 512 AALLLAGLRGLAGA 525
|
|
| AcrA |
COG0845 |
Multidrug efflux pump subunit AcrA (membrane-fusion protein) [Cell wall/membrane/envelope ... |
1188-1276 |
7.29e-03 |
|
Multidrug efflux pump subunit AcrA (membrane-fusion protein) [Cell wall/membrane/envelope biogenesis, Defense mechanisms];
Pssm-ID: 440606 [Multi-domain] Cd Length: 324 Bit Score: 40.31 E-value: 7.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958407961 1188 VRLDAARIRA-YEQAMADHSAALRDEETARADIEHQRLLAEdyTRPVTERAYDhdadgygTYQQRIDQAHKRLEQAQQRR 1266
Cdd:COG0845 52 ARLDPPDLQAaLAQAQAQLAAAQAQLELAKAELERYKALLK--KGAVSQQELD-------QAKAALDQAQAALAAAQAAL 122
|
90
....*....|
gi 1958407961 1267 SLAQQAIEDT 1276
Cdd:COG0845 123 EQARANLAYT 132
|
|
| |
