|
Name |
Accession |
Description |
Interval |
E-value |
| PRK11269 |
PRK11269 |
glyoxylate carboligase; Provisional |
1-566 |
0e+00 |
|
glyoxylate carboligase; Provisional
Pssm-ID: 183066 [Multi-domain] Cd Length: 591 Bit Score: 965.98 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 1 MPAMNAAVSIMVDEGVDIAFGCPGAAILPLYKAMEEDGRIDHLTVRHEEGATHMADGWARTN-GKVGVAIATSGPGATNL 79
Cdd:PRK11269 4 MRAVDAAVLVLEKEGVTTAFGVPGAAINPFYSAMRKHGGIRHILARHVEGASHMAEGYTRATaGNIGVCIGTSGPAGTDM 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 80 VTGLYTAQADSIPMVCLTGQAVSPKLHQEAFQAVDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAGRPGPVLIDLP 159
Cdd:PRK11269 84 ITGLYSASADSIPILCITGQAPRARLHKEDFQAVDIESIAKPVTKWAVTVREPALVPRVFQQAFHLMRSGRPGPVLIDLP 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 160 LDLAKREITYDAEIDTRLPVPAVEPHLPRVERALDMLLAAERPLILAGGGVILADAGSELRELVEELRVPFQVTLMGKGV 239
Cdd:PRK11269 164 FDVQVAEIEFDPDTYEPLPVYKPAATRAQIEKALEMLNAAERPLIVAGGGVINADASDLLVEFAELTGVPVIPTLMGWGA 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 240 IEDDHELNLGTTGIQTSQRYANASFLESDFVLAVGARFGDRHTGAnIDIYRGERTFVHVDIEPAQIGKVFEPDLGIVSDA 319
Cdd:PRK11269 244 IPDDHPLMAGMVGLQTSHRYGNATLLASDFVLGIGNRWANRHTGS-VEVYTKGRKFVHVDIEPTQIGRVFGPDLGIVSDA 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 320 GLFLTALLAEARKRKAR---ADVGSWVERCQELKRTLVRREDFDSTPVKAPRAYKEINEAFDENTYFVTAIGLYQIWGGQ 396
Cdd:PRK11269 323 KAALELLVEVAREWKAAgrlPDRSAWVADCQERKRTLLRKTHFDNVPIKPQRVYEEMNKAFGRDTCYVSTIGLSQIAAAQ 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 397 HQKAYLPRHYQVCGQAGPLGWEVPAAIGVKKAlegmgEPDAEVVGIVGDYGFQYLVEELAVAAQYNVPYVLIMLNNEYLG 476
Cdd:PRK11269 403 FLHVYKPRHWINCGQAGPLGWTIPAALGVRAA-----DPDRNVVALSGDYDFQFLIEELAVGAQFNLPYIHVLVNNAYLG 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 477 LIRQAEIGYGMNYQVDIHYDE--------FGTDNVKLMEAYGCSGQRVWEPADISGAIQWARKEAVATSRPVLVEIMIER 548
Cdd:PRK11269 478 LIRQAQRAFDMDYCVQLAFENinspelngYGVDHVKVAEGLGCKAIRVFKPEDIAPALEQAKALMAEFRVPVVVEVILER 557
|
570
....*....|....*...
gi 1941825792 549 EANTPHGPDIDAVREFEE 566
Cdd:PRK11269 558 VTNISMGTEIDAVNEFEE 575
|
|
| Gcl |
COG3960 |
Glyoxylate carboligase [Secondary metabolites biosynthesis, transport and catabolism]; |
1-566 |
0e+00 |
|
Glyoxylate carboligase [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443160 [Multi-domain] Cd Length: 588 Bit Score: 758.82 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 1 MPAMNAAVSIMVDEGVDIAFGCPGAAILPLYKAMEEDGRIDHLTVRHEEGATHMADGWARTN-GKVGVAIATSGPGATNL 79
Cdd:COG3960 3 MRAVDAAVAVLEKEGVTTAFGVPGAAINPFYSAMRKHGGIRHVLARHVEGASHMAEGYTRAKaGNIGVCIGTSGPAGTDM 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 80 VTGLYTAQADSIPMVCLTGQAVSPKLHQEAFQAVDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAGRPGPVLIDLP 159
Cdd:COG3960 83 ITGLYSASADSIPILCITGQAPRARLHKEDFQAVDIESIAKPVTKWAVTVLEPAQVPRVFQQAFHLMRSGRPGPVLIDLP 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 160 LDLAKREITYDaeIDTRLPVPAVEPHLPR--VERALDMLLAAERPLILAGGGVILADAGSELRELVEELRVPFQVTLMGK 237
Cdd:COG3960 163 IDVQMAEIEFD--IDTYEPLPVYKPAATRaqIEKALDMLNAAERPLIVAGGGIINADASDLLVEFAELTGVPVIPTLMGW 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 238 GVIEDDHELNLGTTGIQTSQRYANASFLESDFVLAVGARFGDRHTGaNIDIYRGERTFVHVDIEPAQIGKVFEPDLGIVS 317
Cdd:COG3960 241 GSIPDDHPLMAGMVGLQTSHRYGNATLLASDFVLGIGNRWANRHTG-SLDVYTKGRKFVHVDIEPTQIGRVFAPDLGIVS 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 318 DAGLFLTALLAEARKRKARA---DVGSWVERCQELKRTLVRREDFDSTPVKAPRAYKEINEAFDENTYFVTAIGLYQIWG 394
Cdd:COG3960 320 DAKAALELFVEVARERKAAGklpDRSAWAAECQERKRTMLRKTHFDNVPIKPQRVYEEMNKAFGRDTRYVSTIGLSQIAA 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 395 GQHQKAYLPRHYQVCGQAGPLGWEVPAAIGVKKAlegmgEPDAEVVGIVGDYGFQYLVEELAVAAQYNVPYVLIMLNNEY 474
Cdd:COG3960 400 AQFLHVYKPRHWINCGQAGPLGWTIPAALGVVAA-----DPDRPVVALSGDYDFQFMIEELAVGAQFKLPYIHVVVNNSY 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 475 LGLIRQAEIGYGMNYQVDIHYD--------EFGTDNVKLMEAYGCSGQRVWEPADISGAIQWARKEAVATSRPVLVEIMI 546
Cdd:COG3960 475 LGLIRQAQRGFDMDYCVQLAFEninapelgGYGVDHVKVAEGLGCKAIRVTDPEEIAPAFEEAKALMAEHRVPVVVEVIL 554
|
570 580
....*....|....*....|
gi 1941825792 547 EREANTPHGPDIDAVREFEE 566
Cdd:COG3960 555 ERVTNISMGTEIDNVNEFEE 574
|
|
| glyox_carbo_lig |
TIGR01504 |
glyoxylate carboligase; Glyoxylate carboligase, also called tartronate-semialdehyde synthase, ... |
1-566 |
0e+00 |
|
glyoxylate carboligase; Glyoxylate carboligase, also called tartronate-semialdehyde synthase, releases CO2 while synthesizing a single molecule of tartronate semialdehyde from two molecules of glyoxylate. It is a thiamine pyrophosphate-dependent enzyme, closely related in sequence to the large subunit of acetolactate synthase. In the D-glycerate pathway, part of allantoin degradation in the Enterobacteriaceae, tartronate semialdehyde is converted to D-glycerate and then 3-phosphoglycerate, a product of glycolysis and entry point in the general metabolism.
Pssm-ID: 213633 [Multi-domain] Cd Length: 588 Bit Score: 622.37 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 1 MPAMNAAVSIMVDEGVDIAFGCPGAAILPLYKAMEEDGRIDHLTVRHEEGATHMADGWARTN-GKVGVAIATSGPGATNL 79
Cdd:TIGR01504 3 MRAVDAAVYVLEKEGITTAFGVPGAAINPFYSALKAHGGIRHILARHVEGASHMAEGYTRATaGNIGVCIGTSGPAGTDM 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 80 VTGLYTAQADSIPMVCLTGQAVSPKLHQEAFQAVDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAGRPGPVLIDLP 159
Cdd:TIGR01504 83 ITGLYSASADSIPILCITGQAPRARLHKEDFQAVDIAAIAKPVSKMAVTVREAALVPRVLQQAFHLMRSGRPGPVLIDLP 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 160 LDLAKREITYDaeIDTRLPVPAVEPHLPRV--ERALDMLLAAERPLILAGGGVILADAGSELRELVEELRVPFQVTLMGK 237
Cdd:TIGR01504 163 FDVQVAEIEFD--PDTYEPLPVYKPAATRAqiEKAVEMLNAAERPLIVAGGGVINADAADLLQEFAELTGVPVIPTLMGW 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 238 GVIEDDHELNLGTTGIQTSQRYANASFLESDFVLAVGARFGDRHTGAnIDIYRGERTFVHVDIEPAQIGKVFEPDLGIVS 317
Cdd:TIGR01504 241 GCIPDDHELMAGMVGLQTSHRYGNATLLESDFVFGIGNRWANRHTGS-VDVYTEGRKFVHVDIEPTQIGRVFAPDLGIVS 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 318 DAGLFLTALLAEARKRKARA---DVGSWVERCQELKRTLVRREDFDSTPVKAPRAYKEINEAFDENTYFVTAIGLYQIWG 394
Cdd:TIGR01504 320 DAKAALKLLVEVAQELKKAGrlpDRSEWAADCQQRKRTLLRKTHFDNVPVKPQRVYEEMNKAFGRDVCYVTTIGLSQIAG 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 395 GQHQKAYLPRHYQVCGQAGPLGWEVPAAIGVKKAlegmgEPDAEVVGIVGDYGFQYLVEELAVAAQYNVPYVLIMLNNEY 474
Cdd:TIGR01504 400 AQMLHVYKPRHWINCGQAGPLGWTIPAALGVCAA-----DPKRNVVALSGDYDFQFMIEELAVGAQHNIPYIHVLVNNAY 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 475 LGLIRQAEIGYGMNYQVDIHYDE--------FGTDNVKLMEAYGCSGQRVWEPADISGAIQWARKEAVATSRPVLVEIMI 546
Cdd:TIGR01504 475 LGLIRQAQRAFDMDYCVQLAFENinssevngYGVDHVKVAEGLGCKAIRVFKPEEIAPAFEQAKALMAEHRVPVVVEVIL 554
|
570 580
....*....|....*....|
gi 1941825792 547 EREANTPHGPDIDAVREFEE 566
Cdd:TIGR01504 555 ERVTNISMGSEIDNVVEFED 574
|
|
| IlvB |
COG0028 |
Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme [Amino ... |
2-553 |
0e+00 |
|
Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme [Amino acid transport and metabolism, Coenzyme transport and metabolism]; Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 439799 [Multi-domain] Cd Length: 548 Bit Score: 573.26 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 2 PAMNAA---VSIMVDEGVDIAFGCPGAAILPLYKAMEEDGRIDHLTVRHEEGATHMADGWARTNGKVGVAIATSGPGATN 78
Cdd:COG0028 1 MKMTGAdalVEALEAEGVETVFGVPGGAILPLYDALRRQSGIRHILVRHEQGAAFMADGYARATGKPGVCLVTSGPGATN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 79 LVTGLYTAQADSIPMVCLTGQAVSPKLHQEAFQAVDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAGRPGPVLIDL 158
Cdd:COG0028 81 LVTGLADAYMDSVPVLAITGQVPTSLIGRGAFQEVDQVGLFRPITKWSYLVTDPEDLPEVLRRAFRIATSGRPGPVVLDI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 159 PLDLAKREITYD-AEIDTRLPVPAVEPHLPRVERALDMLLAAERPLILAGGGVILADAGSELRELVEELRVPFQVTLMGK 237
Cdd:COG0028 161 PKDVQAAEAEEEpAPPELRGYRPRPAPDPEAIEEAAELLAAAKRPVILAGGGARRAGAAEELRALAERLGAPVVTTLMGK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 238 GVIEDDHELNLGTTGIQTSqRYANASFLESDFVLAVGARFGDRHTGaNIDIYRGERTFVHVDIEPAQIGKVFEPDLGIVS 317
Cdd:COG0028 241 GAFPEDHPLYLGMLGMHGT-PAANEALAEADLVLAVGARFDDRVTG-NWDEFAPDAKIIHIDIDPAEIGKNYPVDLPIVG 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 318 DAGLFLTALLAEARKRKarADVGSWVERCQELKRTLVRREDFDSTPVKAPRAYKEINEAFDENTYFVTAIGLYQIWGGQH 397
Cdd:COG0028 319 DAKAVLAALLEALEPRA--DDRAAWLARIAAWRAEYLAAYAADDGPIKPQRVIAALREALPDDAIVVTDVGQHQMWAARY 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 398 QKAYLPRHYQVCGQAGPLGWEVPAAIGVKkalegMGEPDAEVVGIVGDYGFQYLVEELAVAAQYNVPYVLIMLNNEYLGL 477
Cdd:COG0028 397 LRFRRPRRFLTSGGLGTMGYGLPAAIGAK-----LARPDRPVVAITGDGGFQMNLQELATAVRYGLPVKVVVLNNGGLGM 471
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1941825792 478 IRQA-EIGYGMNY-QVDIHydefGTDNVKLMEAYGCSGQRVWEPADISGAIqwarKEAVATSRPVLVEIMIEREANTP 553
Cdd:COG0028 472 VRQWqELFYGGRYsGTDLP----NPDFAKLAEAFGAKGERVETPEELEAAL----EEALASDGPALIDVRVDPEENPP 541
|
|
| acolac_lg |
TIGR00118 |
acetolactate synthase, large subunit, biosynthetic type; Two groups of proteins form ... |
1-551 |
2.91e-174 |
|
acetolactate synthase, large subunit, biosynthetic type; Two groups of proteins form acetolactate from two molecules of pyruvate. The type of acetolactate synthase described in this model also catalyzes the formation of acetohydroxybutyrate from pyruvate and 2-oxobutyrate, an early step in the branched chain amino acid biosynthesis; it is therefore also termed acetohydroxyacid synthase. In bacteria, this catalytic chain is associated with a smaller regulatory chain in an alpha2/beta2 heterotetramer. Acetolactate synthase is a thiamine pyrophosphate enzyme. In this type, FAD and Mg++ are also found. Several isozymes of this enzyme are found in E. coli K12, one of which contains a frameshift in the large subunit gene and is not expressed. [Amino acid biosynthesis, Pyruvate family]
Pssm-ID: 272915 [Multi-domain] Cd Length: 558 Bit Score: 504.64 E-value: 2.91e-174
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 1 MPAMNAAVSIMVDEGVDIAFGCPGAAILPLYKAMEEDGRIDHLTVRHEEGATHMADGWARTNGKVGVAIATSGPGATNLV 80
Cdd:TIGR00118 1 MSGAEAIIESLKDEGVKTVFGYPGGAILPIYDALYNDSGIEHILVRHEQGAAHAADGYARASGKVGVVLVTSGPGATNLV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 81 TGLYTAQADSIPMVCLTGQAVSPKLHQEAFQAVDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAGRPGPVLIDLPL 160
Cdd:TIGR00118 81 TGIATAYMDSIPMVVFTGQVPTSLIGSDAFQEADILGITMPITKHSFQVKSAEDIPRIIKEAFHIATTGRPGPVLVDLPK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 161 DLAKREITYDAEIDTRLP--VPAVEPHLPRVERALDMLLAAERPLILAGGGVILADAGSELRELVEELRVPFQVTLMGKG 238
Cdd:TIGR00118 161 DVTTAEIEYPYPEKVNLPgyRPTVKGHPLQIKKAAELINLAKKPVILVGGGVIIAGASEELKELAERIQIPVTTTLMGLG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 239 VIEDDHELNLGTTGIQTSqRYANASFLESDFVLAVGARFGDRHTGaNIDIYRGERTFVHVDIEPAQIGKVFEPDLGIVSD 318
Cdd:TIGR00118 241 SFPEDHPLSLGMLGMHGT-KTANLAVHECDLIIAVGARFDDRVTG-NLAKFAPNAKIIHIDIDPAEIGKNVRVDIPIVGD 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 319 AGLFLTALLAEARKRKARADVgSWVERCQELKRTLVRREDFDSTPVKAPRAYKEINEAFDENTYFVTAIGLYQIWGGQHQ 398
Cdd:TIGR00118 319 ARNVLEELLKKLFELKERKES-AWLEQINKWKKEYPLKMDYTEEGIKPQQVIEELSRVTKDEAIVTTDVGQHQMWAAQFY 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 399 KAYLPRHYQVCGQAGPLGWEVPAAIGVKkalegMGEPDAEVVGIVGDYGFQYLVEELAVAAQYNVPYVLIMLNNEYLGLI 478
Cdd:TIGR00118 398 PFRKPRRFITSGGLGTMGFGLPAAIGAK-----VAKPESTVICITGDGSFQMNLQELSTAVQYDIPVKILILNNRYLGMV 472
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1941825792 479 RQ-AEIGYGMNYQvDIHYDEfGTDNVKLMEAYGCSGQRVWEPADISGAIqwarKEAVATSRPVLVEIMIEREAN 551
Cdd:TIGR00118 473 RQwQELFYEERYS-HTHMGS-LPDFVKLAEAYGIKGIRIEKPEELDEKL----KEALSSNEPVLLDVVVDKPEN 540
|
|
| PRK06276 |
PRK06276 |
acetolactate synthase large subunit; |
1-563 |
3.46e-158 |
|
acetolactate synthase large subunit;
Pssm-ID: 235766 [Multi-domain] Cd Length: 586 Bit Score: 464.61 E-value: 3.46e-158
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 1 MPAMNAAVSIMVDEGVDIAFGCPGAAILPLYKAMEeDGRIDHLTVRHEEGATHMADGWARTNGKVGVAIATSGPGATNLV 80
Cdd:PRK06276 1 MKGAEAIIKALEAEGVKIIFGYPGGALLPFYDALY-DSDLIHILTRHEQAAAHAADGYARASGKVGVCVATSGPGATNLV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 81 TGLYTAQADSIPMVCLTGQAVSPKLHQEAFQAVDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAGRPGPVLIDLPL 160
Cdd:PRK06276 80 TGIATAYADSSPVIALTGQVPTKLIGNDAFQEIDALGIFMPITKHNFQIKKPEEIPEIFRAAFEIAKTGRPGPVHIDLPK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 161 DLAKREI-TYDAEIDTRLPVPAVEP----HLPRVERALDMLLAAERPLILAGGGVILADAGSELRELVEELRVPFQVTLM 235
Cdd:PRK06276 160 DVQEGELdLEKYPIPAKIDLPGYKPttfgHPLQIKKAAELIAEAERPVILAGGGVIISGASEELIELSELVKIPVCTTLM 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 236 GKGVIEDDHELNLGTTGIQTSQrYANASFLESDFVLAVGARFGDRHTGaNIDIYRGERTFVHVDIEPAQIGKVFEPDLGI 315
Cdd:PRK06276 240 GKGAFPEDHPLALGMVGMHGTK-AANYSVTESDVLIAIGCRFSDRTTG-DISSFAPNAKIIHIDIDPAEIGKNVRVDVPI 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 316 VSDAGLFLTALLAEARKRKARADvGSWVERCQELKRTLVRREDFDSTPVKAPRAYKEINEAFDE-----NTYFVTAIGLY 390
Cdd:PRK06276 318 VGDAKNVLRDLLAELMKKEIKNK-SEWLERVKKLKKESIPRMDFDDKPIKPQRVIKELMEVLREidpskNTIITTDVGQN 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 391 QIWGGQHQKAYLPRHYQVCGQAGPLGWEVPAAIGVKKALegmgePDAEVVGIVGDYGFQYLVEELAVAAQYNVPYVLIML 470
Cdd:PRK06276 397 QMWMAHFFKTSAPRSFISSGGLGTMGFGFPAAIGAKVAK-----PDANVIAITGDGGFLMNSQELATIAEYDIPVVICIF 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 471 NNEYLGLIRQAEIGYGMNYQVDIHYDEfGTDNVKLMEAYGCSGQRVWEPADISGAIqwarKEAVATSRPVLVEIMIEREA 550
Cdd:PRK06276 472 DNRTLGMVYQWQNLYYGKRQSEVHLGE-TPDFVKLAESYGVKADRVEKPDEIKEAL----KEAIKSGEPYLLDIIIDPAE 546
|
570
....*....|...
gi 1941825792 551 NTPHGPDIDAVRE 563
Cdd:PRK06276 547 ALPMVPPGGNLTN 559
|
|
| PRK06048 |
PRK06048 |
acetolactate synthase large subunit; |
1-566 |
9.68e-150 |
|
acetolactate synthase large subunit;
Pssm-ID: 180368 [Multi-domain] Cd Length: 561 Bit Score: 441.91 E-value: 9.68e-150
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 1 MPAMNAAVSIMVDEGVDIAFGCPGAAILPLYKAMEeDGRIDHLTVRHEEGATHMADGWARTNGKVGVAIATSGPGATNLV 80
Cdd:PRK06048 8 MTGARAIIKCLEKEGVEVIFGYPGGAIIPVYDELY-DSDLRHILVRHEQAAAHAADGYARATGKVGVCVATSGPGATNLV 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 81 TGLYTAQADSIPMVCLTGQAVSPKLHQEAFQAVDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAGRPGPVLIDLPL 160
Cdd:PRK06048 87 TGIATAYMDSVPIVALTGQVPRSMIGNDAFQEADITGITMPITKHNYLVQDAKDLPRIIKEAFHIASTGRPGPVLIDLPK 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 161 DLAKREI--TYDAEIDTRLPVPAVEPHLPRVERALDMLLAAERPLILAGGGVILADAGSELRELVEELRVPFQVTLMGKG 238
Cdd:PRK06048 167 DVTTAEIdfDYPDKVELRGYKPTYKGNPQQIKRAAELIMKAERPIIYAGGGVISSNASEELVELAETIPAPVTTTLMGIG 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 239 VIEDDHELNLGTTGIQTSqRYANASFLESDFVLAVGARFGDRHTGaNIDIYRGERTFVHVDIEPAQIGKVFEPDLGIVSD 318
Cdd:PRK06048 247 AIPTEHPLSLGMLGMHGT-KYANYAIQESDLIIAVGARFDDRVTG-KLASFAPNAKIIHIDIDPAEISKNVKVDVPIVGD 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 319 AGLFLTALLaearKRKARADVGSWVERCQELKRTLVRREDFDSTPVKAPRAYKEINEAFdENTYFVTAIGLYQIWGGQHQ 398
Cdd:PRK06048 325 AKQVLKSLI----KYVQYCDRKEWLDKINQWKKEYPLKYKEREDVIKPQYVIEQIYELC-PDAIIVTEVGQHQMWAAQYF 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 399 KAYLPRHYQVCGQAGPLGWEVPAAIGVKkalegMGEPDAEVVGIVGDYGFQYLVEELAVAAQYNVPYVLIMLNNEYLGLI 478
Cdd:PRK06048 400 KYKYPRTFITSGGLGTMGYGFPAAIGAK-----VGKPDKTVIDIAGDGSFQMNSQELATAVQNDIPVIVAILNNGYLGMV 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 479 RQ-AEIGYGMNYQVDIHYDEfgTDNVKLMEAYGCSGQRVWEPADISGAIqwarKEAVATSRPVLVEIMIEREAN----TP 553
Cdd:PRK06048 475 RQwQELFYDKRYSHTCIKGS--VDFVKLAEAYGALGLRVEKPSEVRPAI----EEAVASDRPVVIDFIVECEENvspmVP 548
|
570
....*....|...
gi 1941825792 554 HGPDIDAVREFEE 566
Cdd:PRK06048 549 AGAAINEILDLEE 561
|
|
| PRK07418 |
PRK07418 |
acetolactate synthase large subunit; |
15-551 |
1.79e-139 |
|
acetolactate synthase large subunit;
Pssm-ID: 236014 [Multi-domain] Cd Length: 616 Bit Score: 417.53 E-value: 1.79e-139
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 15 GVDIAFGCPGAAILPLYKAM---EEDGRIDHLTVRHEEGATHMADGWARTNGKVGVAIATSGPGATNLVTGLYTAQADSI 91
Cdd:PRK07418 33 GVKHIFGYPGGAILPIYDELykaEAEGWLKHILVRHEQGAAHAADGYARATGKVGVCFGTSGPGATNLVTGIATAQMDSV 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 92 PMVCLTGQAVSPKLHQEAFQAVDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAGRPGPVLIDLPLDLAKREITYD- 170
Cdd:PRK07418 113 PMVVITGQVPRPAIGTDAFQETDIFGITLPIVKHSYVVRDPSDMARIVAEAFHIASSGRPGPVLIDIPKDVGQEEFDYVp 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 171 ---AEIDTRLPVPAVEPHLPRVERALDMLLAAERPLILAGGGVILADAGSELRELVEELRVPFQVTLMGKGVIEDDHELN 247
Cdd:PRK07418 193 vepGSVKPPGYRPTVKGNPRQINAALKLIEEAERPLLYVGGGAISAGAHAELKELAERFQIPVTTTLMGKGAFDEHHPLS 272
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 248 LGTTGIQTSQrYANASFLESDFVLAVGARFGDRHTGaNIDIYRGERTFVHVDIEPAQIGKVFEPDLGIVSDAGLFLTALL 327
Cdd:PRK07418 273 VGMLGMHGTA-YANFAVTECDLLIAVGARFDDRVTG-KLDEFASRAKVIHIDIDPAEVGKNRRPDVPIVGDVRKVLVKLL 350
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 328 AEARKRKARADVGSWVERCQELKRTLvrredfdstPVKAPRAYKEI--NEAFDE------NTYFVTAIGLYQIWGGQhqk 399
Cdd:PRK07418 351 ERSLEPTTPPRTQAWLERINRWKQDY---------PLVVPPYEGEIypQEVLLAvrdlapDAYYTTDVGQHQMWAAQ--- 418
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 400 aYL---PRHYQVCGQAGPLGWEVPAAIGVKKALegmgePDAEVVGIVGDYGFQYLVEELAVAAQYNVPYVLIMLNNEYLG 476
Cdd:PRK07418 419 -FLrngPRRWISSAGLGTMGFGMPAAMGVKVAL-----PDEEVICIAGDASFLMNIQELGTLAQYGINVKTVIINNGWQG 492
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1941825792 477 LIRQ-AEIGYGMNYQvdiHYD-EFGT-DNVKLMEAYGCSGQRVWEPADISGAIQwarkEAVATSRPVLVEIMIEREAN 551
Cdd:PRK07418 493 MVRQwQESFYGERYS---ASNmEPGMpDFVKLAEAFGVKGMVISERDQLKDAIA----EALAHDGPVLIDVHVRRDEN 563
|
|
| ilvB |
CHL00099 |
acetohydroxyacid synthase large subunit |
11-551 |
9.69e-133 |
|
acetohydroxyacid synthase large subunit
Pssm-ID: 214363 [Multi-domain] Cd Length: 585 Bit Score: 399.07 E-value: 9.69e-133
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 11 MVDEGVDIAFGCPGAAILPLYK---AMEEDGRIDHLTVRHEEGATHMADGWARTNGKVGVAIATSGPGATNLVTGLYTAQ 87
Cdd:CHL00099 20 LVRHGVKHIFGYPGGAILPIYDelyAWEKKGLIKHILVRHEQGAAHAADGYARSTGKVGVCFATSGPGATNLVTGIATAQ 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 88 ADSIPMVCLTGQAVSPKLHQEAFQAVDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAGRPGPVLIDLPLDLAKREI 167
Cdd:CHL00099 100 MDSVPLLVITGQVGRAFIGTDAFQEVDIFGITLPIVKHSYVVRDARDISRIVAEAFYIAKHGRPGPVLIDIPKDVGLEKF 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 168 TYDAEIDTRLPV------PAVEPHLPRVERALDMLLAAERPLILAGGGVILADAGSELRELVEELRVPFQVTLMGKGVIE 241
Cdd:CHL00099 180 DYYPPEPGNTIIkilgcrPIYKPTIKRIEQAAKLILQSSQPLLYVGGGAIISDAHQEITELAELYKIPVTTTLMGKGIFD 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 242 DDHELNLGTTGIQTSQrYANASFLESDFVLAVGARFGDRHTGaNIDIYRGERTFVHVDIEPAQIGKVFEPDLGIVSDAGL 321
Cdd:CHL00099 260 EDHPLCLGMLGMHGTA-YANFAVSECDLLIALGARFDDRVTG-KLDEFACNAQVIHIDIDPAEIGKNRIPQVAIVGDVKK 337
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 322 FLTALLAEARKRK---ARADVGSWVERCQELKRT---LVRRedfDSTPVKAPRAYKEINEaFDENTYFVTAIGLYQIWGG 395
Cdd:CHL00099 338 VLQELLELLKNSPnllESEQTQAWRERINRWRKEyplLIPK---PSTSLSPQEVINEISQ-LAPDAYFTTDVGQHQMWAA 413
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 396 QHQKAYlPRHYQVCGQAGPLGWEVPAAIGVKKAlegmgEPDAEVVGIVGDYGFQYLVEELAVAAQYNVPYVLIMLNNEYL 475
Cdd:CHL00099 414 QFLKCK-PRKWLSSAGLGTMGYGLPAAIGAQIA-----HPNELVICISGDASFQMNLQELGTIAQYNLPIKIIIINNKWQ 487
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1941825792 476 GLIRQ-AEIGYGMNYQvdiH--YDEFGTDNVKLMEAYGCSGQRVWEPADISGAIQwarkEAVATSRPVLVEIMIEREAN 551
Cdd:CHL00099 488 GMVRQwQQAFYGERYS---HsnMEEGAPDFVKLAEAYGIKGLRIKSRKDLKSSLK----EALDYDGPVLIDCQVIEDEN 559
|
|
| PRK07282 |
PRK07282 |
acetolactate synthase large subunit; |
15-548 |
1.32e-132 |
|
acetolactate synthase large subunit;
Pssm-ID: 180919 [Multi-domain] Cd Length: 566 Bit Score: 398.43 E-value: 1.32e-132
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 15 GVDIAFGCPGAAILPLYKAMEEDGRIDHLTVRHEEGATHMADGWARTNGKVGVAIATSGPGATNLVTGLYTAQADSIPMV 94
Cdd:PRK07282 24 GVDTIFGYPGGAVLPLYDAIYNFEGIRHILARHEQGALHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPLL 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 95 CLTGQAVSPKLHQEAFQAVDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAGRPGPVLIDLPLDLAKREITYDAEID 174
Cdd:PRK07282 104 VFTGQVARAGIGKDAFQEADIVGITMPITKYNYQIRETADIPRIITEAVHIATTGRPGPVVIDLPKDVSALETDFIYDPE 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 175 TRLPV--PAVEPHLPRVERALDMLLAAERPLILAGGGVILADAGSELRELVEELRVPFQVTLMGKGVIEDDHELNLGTTG 252
Cdd:PRK07282 184 VNLPSyqPTLEPNDMQIKKILKQLSKAKKPVILAGGGINYAEAATELNAFAERYQIPVVTTLLGQGTIATSHPLFLGMGG 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 253 IQTSQRyANASFLESDFVLAVGARFGDRHTGaNIDIYRGERTFVHVDIEPAQIGKVFEPDLGIVSDAGLFLTALLAEark 332
Cdd:PRK07282 264 MHGSYA-ANIAMTEADFMINIGSRFDDRLTG-NPKTFAKNAKVAHIDIDPAEIGKIIKTDIPVVGDAKKALQMLLAE--- 338
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 333 RKARADVGSWVERCQELKRTlVRREDFDSTPVKAPRAYKEINEAFDENTYFVTAIGLYQIWGGQHQKAYLPRHYQVCGQA 412
Cdd:PRK07282 339 PTVHNNTEKWIEKVTKDKNR-VRSYDKKERVVQPQAVIERIGELTNGDAIVVTDVGQHQMWAAQYYPYQNERQLVTSGGL 417
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 413 GPLGWEVPAAIGVKKAlegmgEPDAEVVGIVGDYGFQYLVEELAVAAQYNVPYVLIMLNNEYLGLIRQAEIGYgmnyqvd 492
Cdd:PRK07282 418 GTMGFGIPAAIGAKIA-----NPDKEVILFVGDGGFQMTNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESF------- 485
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1941825792 493 ihYDE------FGTD-NVKLM-EAYGCSGQRVWEPADISGAIqwarkEAVATSRPVLVEIMIER 548
Cdd:PRK07282 486 --YEGrtsesvFDTLpDFQLMaQAYGIKHYKFDNPETLAQDL-----EVITEDVPMLIEVDISR 542
|
|
| PRK07789 |
PRK07789 |
acetolactate synthase 1 catalytic subunit; Validated |
15-550 |
5.40e-130 |
|
acetolactate synthase 1 catalytic subunit; Validated
Pssm-ID: 236098 [Multi-domain] Cd Length: 612 Bit Score: 393.19 E-value: 5.40e-130
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 15 GVDIAFGCPGAAILPLYKAMEEDGRIDHLTVRHEEGATHMADGWARTNGKVGVAIATSGPGATNLVTGLYTAQADSIPMV 94
Cdd:PRK07789 45 GVDVVFGIPGGAILPVYDPLFDSTKVRHVLVRHEQGAGHAAEGYAQATGRVGVCMATSGPGATNLVTPIADANMDSVPVV 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 95 CLTGQAVSPKLHQEAFQAVDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAGRPGPVLIDLPLDLAKREITYDAEID 174
Cdd:PRK07789 125 AITGQVGRGLIGTDAFQEADIVGITMPITKHNFLVTDADDIPRVIAEAFHIASTGRPGPVLVDIPKDALQAQTTFSWPPR 204
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 175 TRLP--VPAVEPHLPRVERALDMLLAAERPLILAGGGVILADAGSELRELVEELRVPFQVTLMGKGVIEDDHELNLGTTG 252
Cdd:PRK07789 205 MDLPgyRPVTKPHGKQIREAAKLIAAARRPVLYVGGGVIRAEASAELRELAELTGIPVVTTLMARGAFPDSHPQHLGMPG 284
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 253 IQTSQRyANASFLESDFVLAVGARFGDRHTGaNIDIYRGERTFVHVDIEPAQIGKVFEPDLGIVSDAGLFLTALLAEARK 332
Cdd:PRK07789 285 MHGTVA-AVAALQRSDLLIALGARFDDRVTG-KLDSFAPDAKVIHADIDPAEIGKNRHADVPIVGDVKEVIAELIAALRA 362
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 333 RKA---RADVGSWVERCQELKRTLVRREDFDSTPVKAPRAY-KEINEAFDENTYFVTAIGLYQIWGGQHQKAYLPRHYQV 408
Cdd:PRK07789 363 EHAaggKPDLTAWWAYLDGWRETYPLGYDEPSDGSLAPQYViERLGEIAGPDAIYVAGVGQHQMWAAQFIDYEKPRTWLN 442
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 409 CGQAGPLGWEVPAAIGVKkalegMGEPDAEVVGIVGDYGFQYLVEELAVAAQYNVPYVLIMLNNEYLGLIRQAE-IGYGM 487
Cdd:PRK07789 443 SGGLGTMGYAVPAAMGAK-----VGRPDKEVWAIDGDGCFQMTNQELATCAIEGIPIKVALINNGNLGMVRQWQtLFYEE 517
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1941825792 488 NY-QVDIH-YDEFGTDNVKLMEAYGCSGQRVWEPADISGAIQWARKeavATSRPVLVEIMIEREA 550
Cdd:PRK07789 518 RYsNTDLHtHSHRIPDFVKLAEAYGCVGLRCEREEDVDAVIEKARA---INDRPVVIDFVVGKDA 579
|
|
| PRK06466 |
PRK06466 |
acetolactate synthase 3 large subunit; |
8-548 |
4.88e-125 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 180578 [Multi-domain] Cd Length: 574 Bit Score: 379.09 E-value: 4.88e-125
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 8 VSIMVDEGVDIAFGCPGAAILPLYKAMEEDGRIDHLTVRHEEGATHMADGWARTNGKVGVAIATSGPGATNLVTGLYTAQ 87
Cdd:PRK06466 11 VRALRDEGVEYIYGYPGGAVLHIYDALFKQDKVEHILVRHEQAATHMADGYARATGKTGVVLVTSGPGATNAITGIATAY 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 88 ADSIPMVCLTGQAVSPKLHQEAFQAVDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAGRPGPVLIDLPLDLA---- 163
Cdd:PRK06466 91 MDSIPMVVLSGQVPSTLIGEDAFQETDMVGISRPIVKHSFMVKHASEIPEIIKKAFYIAQSGRPGPVVVDIPKDMTnpae 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 164 KREITYDAEIDTRLPVPAVEPHLPRVERALDMLLAAERPLILAGGGVILADAGSELRELVEELRVPFQVTLMGKGVIEDD 243
Cdd:PRK06466 171 KFEYEYPKKVKLRSYSPAVRGHSGQIRKAVEMLLAAKRPVIYSGGGVVLGNASALLTELAHLLNLPVTNTLMGLGGFPGT 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 244 HELNLGTTGIQTSQRyANASFLESDFVLAVGARFGDRHTGaNIDIYRGERTFVHVDIEPAQIGKVFEPDLGIVSDAGLFL 323
Cdd:PRK06466 251 DRQFLGMLGMHGTYE-ANMAMHHADVILAVGARFDDRVTN-GPAKFCPNAKIIHIDIDPASISKTIKADIPIVGPVESVL 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 324 T---ALLAEARKRKARADVGSWVERCQELK--RTLVRREDFDSTPVKAPRAYKEINEAFDENTYFVTAIGLYQIWGGQHQ 398
Cdd:PRK06466 329 TemlAILKEIGEKPDKEALAAWWKQIDEWRgrHGLFPYDKGDGGIIKPQQVVETLYEVTNGDAYVTSDVGQHQMFAAQYY 408
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 399 KAYLPRHYQVCGQAGPLGWEVPAAIGVKkalegMGEPDAEVVGIVGDYGFQYLVEELAVAAQYNVPYVLIMLNNEYLGLI 478
Cdd:PRK06466 409 KFNKPNRWINSGGLGTMGFGLPAAMGVK-----LAFPDQDVACVTGEGSIQMNIQELSTCLQYGLPVKIINLNNGALGMV 483
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1941825792 479 RQAEigyGMNYQV--DIHYDEFGTDNVKLMEAYGCSGQRVWEPADISGAIqwarKEAVA-TSRPVLVEIMIER 548
Cdd:PRK06466 484 RQWQ---DMQYEGrhSHSYMESLPDFVKLAEAYGHVGIRITDLKDLKPKL----EEAFAmKDRLVFIDIYVDR 549
|
|
| PRK09107 |
PRK09107 |
acetolactate synthase 3 catalytic subunit; Validated |
8-551 |
5.27e-125 |
|
acetolactate synthase 3 catalytic subunit; Validated
Pssm-ID: 236380 [Multi-domain] Cd Length: 595 Bit Score: 379.82 E-value: 5.27e-125
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 8 VSIMVDEGVDIAFGCPGAAILPLYKAMEEDGRIDHLTVRHEEGATHMADGWARTNGKVGVAIATSGPGATNLVTGLYTAQ 87
Cdd:PRK09107 18 VQALKDQGVEHIFGYPGGAVLPIYDEIFQQDDIQHILVRHEQGAGHAAEGYARSTGKPGVVLVTSGPGATNAVTPLQDAL 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 88 ADSIPMVCLTGQAVSPKLHQEAFQAVDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAGRPGPVLIDLPLDL--AKR 165
Cdd:PRK09107 98 MDSIPLVCITGQVPTHLIGSDAFQECDTVGITRPCTKHNWLVKDVNDLARVIHEAFHVATSGRPGPVVVDIPKDVqfATG 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 166 EITYDAEID-TRLPVPAVEPHLPRVERALDMLLAAERPLILAGGGVIlaDAGSE----LRELVEELRVPFQVTLMGKGVI 240
Cdd:PRK09107 178 TYTPPQKAPvHVSYQPKVKGDAEAITEAVELLANAKRPVIYSGGGVI--NSGPEasrlLRELVELTGFPITSTLMGLGAY 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 241 EDDHELNLGTTGIQTSQRyANASFLESDFVLAVGARFGDRHTGaNIDIYRGERTFVHVDIEPAQIGKVFEPDLGIVSDAG 320
Cdd:PRK09107 256 PASGKNWLGMLGMHGTYE-ANMAMHDCDVMLCVGARFDDRITG-RLDAFSPNSKKIHIDIDPSSINKNVRVDVPIIGDVG 333
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 321 LFLTALLA--EARKRKA-RADVGSWVERCQELKrtlvRREDFDSTP----VKAPRAYKEINEAF-DENTYFVTAIGLYQI 392
Cdd:PRK09107 334 HVLEDMLRlwKARGKKPdKEALADWWGQIARWR----ARNSLAYTPsddvIMPQYAIQRLYELTkGRDTYITTEVGQHQM 409
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 393 WGGQHQKAYLPRHYQVCGQAGPLGWEVPAAIGVKKAlegmgEPDAEVVGIVGDYGFQYLVEELAVAAQYNVPYVLIMLNN 472
Cdd:PRK09107 410 WAAQFFGFEEPNRWMTSGGLGTMGYGLPAALGVQIA-----HPDALVIDIAGDASIQMCIQEMSTAVQYNLPVKIFILNN 484
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 473 EYLGLIRQ-AEIGYGMNYQvdiH-YDEFGTDNVKLMEAYGCSGQRVWEPADISGAIQwarkEAVATSRPVLVEIMIEREA 550
Cdd:PRK09107 485 QYMGMVRQwQQLLHGNRLS---HsYTEAMPDFVKLAEAYGAVGIRCEKPGDLDDAIQ----EMIDVDKPVIFDCRVANLE 557
|
.
gi 1941825792 551 N 551
Cdd:PRK09107 558 N 558
|
|
| PRK08527 |
PRK08527 |
acetolactate synthase large subunit; |
11-551 |
1.02e-123 |
|
acetolactate synthase large subunit;
Pssm-ID: 181458 [Multi-domain] Cd Length: 563 Bit Score: 375.21 E-value: 1.02e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 11 MVDEGVDIAFGCPGAAILPLYKAMEEDGRIDHLTVRHEEGATHMADGWARTNGKVGVAIATSGPGATNLVTGLYTAQADS 90
Cdd:PRK08527 13 LKEEGVKVVFGYPGGAILNIYDEIYKQNYFKHILTRHEQAAVHAADGYARASGKVGVAIVTSGPGFTNAVTGLATAYMDS 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 91 IPMVCLTGQAVSPKLHQEAFQAVDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAGRPGPVLIDLPLDL--AKREIT 168
Cdd:PRK08527 93 IPLVLISGQVPNSLIGTDAFQEIDAVGISRPCVKHNYLVKSIEELPRILKEAFYIARSGRPGPVHIDIPKDVtaTLGEFE 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 169 YDAEIDTRLPVPAVEPHLPRVERALDMLLAAERPLILAGGGVILADAGSELRELVEELRVPFQVTLMGKGVIEDDHELNL 248
Cdd:PRK08527 173 YPKEISLKTYKPTYKGNSRQIKKAAEAIKEAKKPLFYLGGGAILSNASEEIRELVKKTGIPAVETLMARGVLRSDDPLLL 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 249 GTTGIQTSqrY-ANASFLESDFVLAVGARFGDRHTGaNIDIYRGERTFVHVDIEPAQIGKVFEPDLGIVSDAGLFLTALL 327
Cdd:PRK08527 253 GMLGMHGS--YaANMAMSECDLLISLGARFDDRVTG-KLSEFAKHAKIIHVDIDPSSISKIVNADYPIVGDLKNVLKEML 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 328 AEArKRKARADVGSWVERCQELKRTL-VRREDFDSTpVKAPRAYKEINEAFDENTYFVTAIGLYQIWGGQHQKAYLPRHY 406
Cdd:PRK08527 330 EEL-KEENPTTYKEWREILKRYNELHpLSYEDSDEV-LKPQWVIERVGELLGDDAIISTDVGQHQMWVAQFYPFNYPRQL 407
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 407 QVCGQAGPLGWEVPAAIGVKKALegmgePDAEVVGIVGDYGFQYLVEELAVAAQYNVPYVLIMLNNEYLGLIRQAE-IGY 485
Cdd:PRK08527 408 ATSGGLGTMGYGLPAALGAKLAV-----PDKVVINFTGDGSILMNIQELMTAVEYKIPVINIILNNNFLGMVRQWQtFFY 482
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1941825792 486 GMNY-QVDIhydEFGTDNVKLMEAYGCSGQRVWEPADISGAIqwarKEAVATSRPVLVEIMIEREAN 551
Cdd:PRK08527 483 EERYsETDL---STQPDFVKLAESFGGIGFRVTTKEEFDKAL----KEALESDKVALIDVKIDRFEN 542
|
|
| PRK07710 |
PRK07710 |
acetolactate synthase large subunit; |
14-551 |
2.67e-123 |
|
acetolactate synthase large subunit;
Pssm-ID: 236076 [Multi-domain] Cd Length: 571 Bit Score: 374.48 E-value: 2.67e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 14 EGVDIAFGCPGAAILPLYKAMEEDGrIDHLTVRHEEGATHMADGWARTNGKVGVAIATSGPGATNLVTGLYTAQADSIPM 93
Cdd:PRK07710 29 EGVEVIFGYPGGAVLPLYDALYDCG-IPHILTRHEQGAIHAAEGYARISGKPGVVIATSGPGATNVVTGLADAMIDSLPL 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 94 VCLTGQAVSPKLHQEAFQAVDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAGRPGPVLIDLPLDLAKREITYDAEI 173
Cdd:PRK07710 108 VVFTGQVATSVIGSDAFQEADIMGITMPVTKHNYQVRKASDLPRIIKEAFHIATTGRPGPVLIDIPKDMVVEEGEFCYDV 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 174 DTRLP--VPAVEPHLPRVERALDMLLAAERPLILAGGGVILADAGSELRELVEELRVPFQVTLMGKGVIEDDHELNLGTT 251
Cdd:PRK07710 188 QMDLPgyQPNYEPNLLQIRKLVQAVSVAKKPVILAGAGVLHAKASKELTSYAEQQEIPVVHTLLGLGGFPADHPLFLGMA 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 252 GIQTSQRyANASFLESDFVLAVGARFGDRHTGaNIDIYRGERTFVHVDIEPAQIGKVFEPDLGIVSDAGLFLTALLAEAR 331
Cdd:PRK07710 268 GMHGTYT-ANMALYECDLLINIGARFDDRVTG-NLAYFAKEATVAHIDIDPAEIGKNVPTEIPIVADAKQALQVLLQQEG 345
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 332 KrkaRADVGSWVERCQELKRTLVRREDFDSTPVKAPRAYKEINEAFDENTYFVTAIGLYQIWGGQHQKAYLPRHYQVCGQ 411
Cdd:PRK07710 346 K---KENHHEWLSLLKNWKEKYPLSYKRNSESIKPQKAIEMLYEITKGEAIVTTDVGQHQMWAAQYYPFKTPDKWVTSGG 422
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 412 AGPLGWEVPAAIGVKKAlegmgEPDAEVVGIVGDYGFQYLVEELAVAAQYNVPYVLIMLNNEYLGLIRQ-AEIGYGMNYQ 490
Cdd:PRK07710 423 LGTMGFGLPAAIGAQLA-----KPDETVVAIVGDGGFQMTLQELSVIKELSLPVKVVILNNEALGMVRQwQEEFYNQRYS 497
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1941825792 491 VDIHYDEfgTDNVKLMEAYGCSGQRVWEPADISGAIqwarKEAVATSRPVLVEIMIEREAN 551
Cdd:PRK07710 498 HSLLSCQ--PDFVKLAEAYGIKGVRIDDELEAKEQL----QHAIELQEPVVIDCRVLQSEK 552
|
|
| PRK06965 |
PRK06965 |
acetolactate synthase 3 catalytic subunit; Validated |
8-531 |
7.36e-123 |
|
acetolactate synthase 3 catalytic subunit; Validated
Pssm-ID: 180780 [Multi-domain] Cd Length: 587 Bit Score: 373.75 E-value: 7.36e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 8 VSIMVDEGVDIAFGCPGAAILPLYKAMEEDGRIDHLTVRHEEGATHMADGWARTNGKVGVAIATSGPGATNLVTGLYTAQ 87
Cdd:PRK06965 28 MKALAAEGVEFIWGYPGGAVLYIYDELYKQDKIQHVLVRHEQAAVHAADGYARATGKVGVALVTSGPGVTNAVTGIATAY 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 88 ADSIPMVCLTGQAVSPKLHQEAFQAVDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAGRPGPVLIDLPLDLA--KR 165
Cdd:PRK06965 108 MDSIPMVVISGQVPTAAIGQDAFQECDTVGITRPIVKHNFLVKDVRDLAETVKKAFYIARTGRPGPVVVDIPKDVSktPC 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 166 EITYDAEIDTRLPVPAVEPHLPRVERALDMLLAAERPLILAGGGVILADAGSELRELVEELRVPFQVTLMGKGVIEDDHE 245
Cdd:PRK06965 188 EYEYPKSVEMRSYNPVTKGHSGQIRKAVSLLLSAKRPYIYTGGGVILANASRELRQLADLLGYPVTNTLMGLGAYPASDK 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 246 LNLGTTGIQTSQRyANASFLESDFVLAVGARFGDRHTGANIDIYRGERTFVHVDIEPAQIGKVFEPDLGIVSDAGLFLTA 325
Cdd:PRK06965 268 KFLGMLGMHGTYE-ANMAMQHCDVLIAIGARFDDRVIGNPAHFASRPRKIIHIDIDPSSISKRVKVDIPIVGDVKEVLKE 346
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 326 LLAEARKRKARAD---VGSWVERCQELKRTLVRREDFDSTPVKAPRAYKEINEAFDENTYFVTAIGLYQIWGGQHQKAYL 402
Cdd:PRK06965 347 LIEQLQTAEHGPDadaLAQWWKQIEGWRSRDCLKYDRESEIIKPQYVVEKLWELTDGDAFVCSDVGQHQMWAAQFYRFNE 426
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 403 PRHYQVCGQAGPLGWEVPAAIGVKKAlegmgEPDAEVVGIVGDYGFQYLVEELAVAAQYNVPYVLIMLNNEYLGLIRQ-A 481
Cdd:PRK06965 427 PRRWINSGGLGTMGVGLPYAMGIKMA-----HPDDDVVCITGEGSIQMCIQELSTCLQYDTPVKIISLNNRYLGMVRQwQ 501
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|
gi 1941825792 482 EIGYGMNYQVDihYDEFGTDNVKLMEAYGCSGQRVWEPADISGAIQWARK 531
Cdd:PRK06965 502 EIEYSKRYSHS--YMDALPDFVKLAEAYGHVGMRIEKTSDVEPALREALR 549
|
|
| PRK08978 |
PRK08978 |
acetolactate synthase 2 catalytic subunit; Reviewed |
4-551 |
8.55e-123 |
|
acetolactate synthase 2 catalytic subunit; Reviewed
Pssm-ID: 181601 [Multi-domain] Cd Length: 548 Bit Score: 372.29 E-value: 8.55e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 4 MNAA---VSIMVDEGVDIAFGCPGAAILPLYKAMEeDGRIDHLTVRHEEGATHMADGWARTNGKVGVAIATSGPGATNLV 80
Cdd:PRK08978 1 MNGAqwvVHALRAQGVDTVFGYPGGAIMPVYDALY-DGGVEHLLCRHEQGAAMAAIGYARATGKVGVCIATSGPGATNLI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 81 TGLYTAQADSIPMVCLTGQAVSPKLHQEAFQAVDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAGRPGPVLIDLPL 160
Cdd:PRK08978 80 TGLADALLDSVPVVAITGQVSSPLIGTDAFQEIDVLGLSLACTKHSFLVQSLEELPEIMAEAFEIASSGRPGPVLVDIPK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 161 D--LAkreityDAEIDTRLPVPAVEPHLP--RVERALDMLLAAERPLILAGGGVILADAGSELRELVEELRVPFQVTLMG 236
Cdd:PRK08978 160 DiqLA------EGELEPHLTTVENEPAFPaaELEQARALLAQAKKPVLYVGGGVGMAGAVPALREFLAATGMPAVATLKG 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 237 KGVIEDDHELNLGTTGIQTSqRYANASFLESDFVLAVGARFGDRHTGaNIDIYRGERTFVHVDIEPAQIGKVFEPDLGIV 316
Cdd:PRK08978 234 LGAVEADHPYYLGMLGMHGT-KAANLAVQECDLLIAVGARFDDRVTG-KLNTFAPHAKVIHLDIDPAEINKLRQAHVALQ 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 317 SDAGLFLTALLAEarkrkarADVGSWVERCQELKRTLVRREDFDSTPVKAPRAYKEINEAFDENTYFVTAIGLYQIWGGQ 396
Cdd:PRK08978 312 GDLNALLPALQQP-------LNIDAWRQHCAQLRAEHAWRYDHPGEAIYAPALLKQLSDRKPADTVVTTDVGQHQMWVAQ 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 397 HQKAYLPRHYQVCGQAGPLGWEVPAAIGVKKAlegmgEPDAEVVGIVGDYGFQYLVEELAVAAQYNVPYVLIMLNNEYLG 476
Cdd:PRK08978 385 HMRFTRPENFITSSGLGTMGFGLPAAIGAQVA-----RPDDTVICVSGDGSFMMNVQELGTIKRKQLPVKIVLLDNQRLG 459
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 477 LIRQ-AEIGYGMNY-QVDIhydefgTDN---VKLMEAYGCSGQRVWEPADISGAIqwarKEAVATSRPVLVEIMIEREAN 551
Cdd:PRK08978 460 MVRQwQQLFFDERYsETDL------SDNpdfVMLASAFGIPGQTITRKDQVEAAL----DTLLNSEGPYLLHVSIDELEN 529
|
|
| PRK07979 |
PRK07979 |
acetolactate synthase 3 large subunit; |
8-547 |
6.24e-118 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 181185 [Multi-domain] Cd Length: 574 Bit Score: 360.71 E-value: 6.24e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 8 VSIMVDEGVDIAFGCPGAAILPLYKAMEEDGRIDHLTVRHEEGATHMADGWARTNGKVGVAIATSGPGATNLVTGLYTAQ 87
Cdd:PRK07979 11 VRSLIDQGVKQVFGYPGGAVLDIYDALHTVGGIDHVLVRHEQAAVHMADGLARATGEVGVVLVTSGPGATNAITGIATAY 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 88 ADSIPMVCLTGQAVSPKLHQEAFQAVDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAGRPGPVLIDLPLDLA---- 163
Cdd:PRK07979 91 MDSIPLVVLSGQVATSLIGYDAFQECDMVGISRPVVKHSFLVKQTEDIPQVLKKAFWLAASGRPGPVVVDLPKDILnpan 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 164 KREITYDAEIDTRLPVPAVEPHLPRVERALDMLLAAERPLILAGGGVILADAGSELRELVEELRVPFQVTLMGKGVIEDD 243
Cdd:PRK07979 171 KLPYVWPESVSMRSYNPTTQGHKGQIKRALQTLVAAKKPVVYVGGGAINAACHQQLKELVEKLNLPVVSSLMGLGAFPAT 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 244 HELNLGTTGIQTSQRyANASFLESDFVLAVGARFGDRHTGaNIDIYRGERTFVHVDIEPAQIGKVFEPDLGIVSDAGLFL 323
Cdd:PRK07979 251 HRQSLGMLGMHGTYE-ANMTMHNADVIFAVGVRFDDRTTN-NLAKYCPNATVLHIDIDPTSISKTVTADIPIVGDARQVL 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 324 T---ALLAEARKRKARADVGSWVERCQELKRTLVRREDFDSTPVKaPRAYKEINEAFDENTYFVTA-IGLYQIWGGQHQK 399
Cdd:PRK07979 329 EqmlELLSQESAHQPLDEIRDWWQQIEQWRARQCLKYDTHSEKIK-PQAVIETLWRLTKGDAYVTSdVGQHQMFAALYYP 407
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 400 AYLPRHYQVCGQAGPLGWEVPAAIGVKKALegmgePDAEVVGIVGDYGFQYLVEELAVAAQYNVPYVLIMLNNEYLGLIR 479
Cdd:PRK07979 408 FDKPRRWINSGGLGTMGFGLPAALGVKMAL-----PEETVVCVTGDGSIQMNIQELSTALQYELPVLVLNLNNRYLGMVK 482
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 480 QAE--IGYGMNYQvdiHYDEFGTDNVKLMEAYGCSGQRVWEPADISGAIQWARKEaVATSRPVLVEIMIE 547
Cdd:PRK07979 483 QWQdmIYSGRHSQ---SYMQSLPDFVRLAEAYGHVGIQISHPDELESKLSEALEQ-VRNNRLVFVDVTVD 548
|
|
| PRK06882 |
PRK06882 |
acetolactate synthase 3 large subunit; |
8-529 |
8.85e-117 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 168717 [Multi-domain] Cd Length: 574 Bit Score: 357.69 E-value: 8.85e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 8 VSIMVDEGVDIAFGCPGAAILPLYKAMEEDGRIDHLTVRHEEGATHMADGWARTNGKVGVAIATSGPGATNLVTGLYTAQ 87
Cdd:PRK06882 11 VQSLRDEGVEYVFGYPGGSVLDIYDAIHTLGGIEHVLVRHEQAAVHMADGYARSTGKVGCVLVTSGPGATNAITGIATAY 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 88 ADSIPMVCLTGQAVSPKLHQEAFQAVDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAGRPGPVLIDLPLDLA---- 163
Cdd:PRK06882 91 TDSVPLVILSGQVPSNLIGTDAFQECDMLGISRPVVKHSFIVKNAEDIPSTIKKAFYIASTGRPGPVVIDIPKDMVnpan 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 164 KREITYDAEIDTRLPVPAVEPHLPRVERALDMLLAAERPLILAGGGVILADAGSELRELVEELRVPFQVTLMGKGVIEDD 243
Cdd:PRK06882 171 KFTYEYPEEVSLRSYNPTVQGHKGQIKKALKALLVAKKPVLFVGGGVITAECSEQLTQFAQKLNLPVTSSLMGLGAYPST 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 244 HELNLGTTGIQTSQRyANASFLESDFVLAVGARFGDRHTGaNIDIYRGERTFVHVDIEPAQIGKVFEPDLGIVSDAGLFL 323
Cdd:PRK06882 251 DKQFLGMLGMHGTYE-ANNAMHESDLILGIGVRFDDRTTN-NLAKYCPNAKVIHIDIDPTSISKNVPAYIPIVGSAKNVL 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 324 T---ALLAEARKRKARADVGSWVERCQELKRTLVRREDFDSTPVKAPRAYKEINEAFDENTYFVTAIGLYQIWGGQHQKA 400
Cdd:PRK06882 329 EeflSLLEEENLAKSQTDLTAWWQQINEWKAKKCLEFDRTSDVIKPQQVVEAIYRLTNGDAYVASDVGQHQMFAALHYPF 408
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 401 YLPRHYQVCGQAGPLGWEVPAAIGVKKAlegmgEPDAEVVGIVGDYGFQYLVEELAVAAQYNVPYVLIMLNNEYLGLIRQ 480
Cdd:PRK06882 409 DKPRRWINSGGAGTMGFGLPAAIGVKFA-----HPEATVVCVTGDGSIQMNIQELSTAKQYDIPVVIVSLNNRFLGMVKQ 483
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|.
gi 1941825792 481 AE--IGYGMNYQVdihYDEFGTDNVKLMEAYGCSGQRVWEPADISGAIQWA 529
Cdd:PRK06882 484 WQdlIYSGRHSQV---YMNSLPDFAKLAEAYGHVGIQIDTPDELEEKLTQA 531
|
|
| PRK08979 |
PRK08979 |
acetolactate synthase 3 large subunit; |
8-547 |
1.06e-115 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 181602 [Multi-domain] Cd Length: 572 Bit Score: 354.90 E-value: 1.06e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 8 VSIMVDEGVDIAFGCPGAAILPLYKAMEEDGRIDHLTVRHEEGATHMADGWARTNGKVGVAIATSGPGATNLVTGLYTAQ 87
Cdd:PRK08979 11 VRSLIDEGVKHIFGYPGGSVLDIYDALHEKSGIEHILVRHEQAAVHMADGYARATGKVGVVLVTSGPGATNTITGIATAY 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 88 ADSIPMVCLTGQAVSPKLHQEAFQAVDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAGRPGPVLIDLPLDLAKREI 167
Cdd:PRK08979 91 MDSIPMVVLSGQVPSNLIGNDAFQECDMIGISRPVVKHSFLVKDAEDIPEIIKKAFYIASTGRPGPVVIDLPKDCLNPAI 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 168 TYDAE----IDTRLPVPAVEPHLPRVERALDMLLAAERPLILAGGGVILADAGSELRELVEELRVPFQVTLMGKGVIEDD 243
Cdd:PRK08979 171 LHPYEypesIKMRSYNPTTSGHKGQIKRGLQALLAAKKPVLYVGGGAIISGADKQILQLAEKLNLPVVSTLMGLGAFPGT 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 244 HELNLGTTGIQTsqRY-ANASFLESDFVLAVGARFGDRHTGaNIDIYRGERTFVHVDIEPAQIGKVFEPDLGIVSDAGLF 322
Cdd:PRK08979 251 HKNSLGMLGMHG--RYeANMAMHNADLIFGIGVRFDDRTTN-NLEKYCPNATILHIDIDPSSISKTVRVDIPIVGSADKV 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 323 LT---ALLAEARKRKARADVGSWVERCQELKRTLVRREDFDSTPVKAPRAYKEINEAFDENTYFVTAIGLYQIWGGQHQK 399
Cdd:PRK08979 328 LDsmlALLDESGETNDEAAIASWWNEIEVWRSRNCLAYDKSSERIKPQQVIETLYKLTNGDAYVASDVGQHQMFAALYYP 407
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 400 AYLPRHYQVCGQAGPLGWEVPAAIGVKkalegMGEPDAEVVGIVGDYGFQYLVEELAVAAQYNVPYVLIMLNNEYLGLIR 479
Cdd:PRK08979 408 FDKPRRWINSGGLGTMGFGLPAAMGVK-----FAMPDETVVCVTGDGSIQMNIQELSTALQYDIPVKIINLNNRFLGMVK 482
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1941825792 480 QAEigyGMNYQvDIH---YDEFGTDNVKLMEAYGCSGQRVWEPADISGAIQwarkEAVA-TSRPVLVEIMIE 547
Cdd:PRK08979 483 QWQ---DMIYQ-GRHshsYMDSVPDFAKIAEAYGHVGIRISDPDELESGLE----KALAmKDRLVFVDINVD 546
|
|
| PRK08155 |
PRK08155 |
acetolactate synthase large subunit; |
8-551 |
3.89e-115 |
|
acetolactate synthase large subunit;
Pssm-ID: 181257 [Multi-domain] Cd Length: 564 Bit Score: 353.24 E-value: 3.89e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 8 VSIMVDEGVDIAFGCPGAAILPLYKAMEEDGRIDHLTVRHEEGATHMADGWARTNGKVGVAIATSGPGATNLVTGLYTAQ 87
Cdd:PRK08155 20 VRLLERQGIRIVTGIPGGAILPLYDALSQSTQIRHILARHEQGAGFIAQGMARTTGKPAVCMACSGPGATNLVTAIADAR 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 88 ADSIPMVCLTGQAVSPKLHQEAFQAVDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAGRPGPVLIDLPLDLAKREI 167
Cdd:PRK08155 100 LDSIPLVCITGQVPASMIGTDAFQEVDTYGISIPITKHNYLVRDIEELPQVISDAFRIAQSGRPGPVWIDIPKDVQTAVI 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 168 TYDA--EIDTRLPVPAVEPHLprVERALDMLLAAERPLILAGGGVILADAGSELRELVEELRVPFQVTLMGKGVIEDDHE 245
Cdd:PRK08155 180 ELEAlpAPAEKDAAPAFDEES--IRDAAAMINAAKRPVLYLGGGVINSGAPARARELAEKAQLPTTMTLMALGMLPKAHP 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 246 LNLGTTGIQTSqRYANASFLESDFVLAVGARFGDRHTGanidiyRGER-----TFVHVDIEPAQIGKVFEPDLGIVSDAG 320
Cdd:PRK08155 258 LSLGMLGMHGA-RSTNYILQEADLLIVLGARFDDRAIG------KTEQfcpnaKIIHVDIDRAELGKIKQPHVAIQADVD 330
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 321 LFLTALL--AEARKRKAradvgsWVERCQELKRtlvrreDFdstPVKAPRA------YKEIN---EAFDENTYFVTAIGL 389
Cdd:PRK08155 331 DVLAQLLplVEAQPRAE------WHQLVADLQR------EF---PCPIPKAddplshYGLINavaACVDDNAIITTDVGQ 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 390 YQIWGGQHQKAYLPRHYQVCGQAGPLGWEVPAAIGVKKAlegmgEPDAEVVGIVGDYGFQYLVEELAVAAQYNVPYVLIM 469
Cdd:PRK08155 396 HQMWTAQAYPLNRPRQWLTSGGLGTMGFGLPAAIGAALA-----NPERKVLCFSGDGSLMMNIQEMATAAENQLDVKIIL 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 470 LNNEYLGLIRQaeigygmnyQVDIHYDE--------FGTDNVKLMEAYGCSGQRVWEPADISGAIQwarkEAVATSRPVL 541
Cdd:PRK08155 471 MNNEALGLVHQ---------QQSLFYGQrvfaatypGKINFMQIAAGFGLETCDLNNEADPQAALQ----EAINRPGPAL 537
|
570
....*....|
gi 1941825792 542 VEIMIEREAN 551
Cdd:PRK08155 538 IHVRIDAEEK 547
|
|
| PRK06725 |
PRK06725 |
acetolactate synthase large subunit; |
14-551 |
6.87e-114 |
|
acetolactate synthase large subunit;
Pssm-ID: 180672 [Multi-domain] Cd Length: 570 Bit Score: 350.42 E-value: 6.87e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 14 EGVDIAFGCPGAAILPLYKAMEEDGrIDHLTVRHEEGATHMADGWARTNGKVGVAIATSGPGATNLVTGLYTAQADSIPM 93
Cdd:PRK06725 28 LGVTTVFGYPGGAILPVYDALYESG-LKHILTRHEQAAIHAAEGYARASGKVGVVFATSGPGATNLVTGLADAYMDSIPL 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 94 VCLTGQAVSPKLHQEAFQAVDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAGRPGPVLIDLPLDLAKREIT--YDA 171
Cdd:PRK06725 107 VVITGQVATPLIGKDGFQEADVVGITVPVTKHNYQVRDVNQLSRIVQEAFYIAESGRPGPVLIDIPKDVQNEKVTsfYNE 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 172 EIDTRLPVPAVEPHLPRVERALDMLLAAERPLILAGGGVILADAGSELRELVEELRVPFQVTLMGKGVIEDDHELNLGTT 251
Cdd:PRK06725 187 VVEIPGYKPEPRPDSMKLREVAKAISKAKRPLLYIGGGVIHSGGSEELIEFARENRIPVVSTLMGLGAYPPGDPLFLGML 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 252 GIQTSQRyANASFLESDFVLAVGARFGDRHTGaNIDIYRGERTFVHVDIEPAQIGKVFEPDLGIVSDAGLFLTALLAEAR 331
Cdd:PRK06725 267 GMHGTYA-ANMAVTECDLLLALGVRFDDRVTG-KLELFSPHSKKVHIDIDPSEFHKNVAVEYPVVGDVKKALHMLLHMSI 344
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 332 KRKARAdvgsWVERCQELKRTLVRREDFDSTPVKAPRAYKEINEAFDENTYFVTAIGLYQIWGGQHQKAYLPRHYQVCGQ 411
Cdd:PRK06725 345 HTQTDE----WLQKVKTWKEEYPLSYKQKESELKPQHVINLVSELTNGEAIVTTEVGQHQMWAAHFYKAKNPRTFLTSGG 420
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 412 AGPLGWEVPAAIGVKKAlegmgEPDAEVVGIVGDYGFQYLVEELAVAAQYNVPYVLIMLNNEYLGLIRQAEigyGMNYQV 491
Cdd:PRK06725 421 LGTMGFGFPAAIGAQLA-----KEEELVICIAGDASFQMNIQELQTIAENNIPVKVFIINNKFLGMVRQWQ---EMFYEN 492
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1941825792 492 DIHYDEFGT-DNVKLMEAYGCSGQRVWEPADISGAIqwarKEAVATSRPVLVEIMIEREAN 551
Cdd:PRK06725 493 RLSESKIGSpDFVKVAEAYGVKGLRATNSTEAKQVM----LEAFAHEGPVVVDFCVEEGEN 549
|
|
| PRK06456 |
PRK06456 |
acetolactate synthase large subunit; |
4-550 |
5.07e-106 |
|
acetolactate synthase large subunit;
Pssm-ID: 180569 [Multi-domain] Cd Length: 572 Bit Score: 329.88 E-value: 5.07e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 4 MNAAVSIMVD----EGVDIAFGCPGAAILPLYKAMEED---GRIDHLTVRHEEGATHMADGWARTNGKVGVAIATSGPGA 76
Cdd:PRK06456 1 MPTGARILVDslkrEGVKVIFGIPGLSNMQIYDAFVEDlanGELRHVLMRHEQAAAHAADGYARASGVPGVCTATSGPGT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 77 TNLVTGLYTAQADSIPMVCLTGQAVSPKLHQEAFQAVDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAGRPGPVLI 156
Cdd:PRK06456 81 TNLVTGLITAYWDSSPVIAITGQVPRSVMGKMAFQEADAMGVFENVTKYVIGIKRIDEIPQWIKNAFYIATTGRPGPVVI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 157 DLPLDLAKREITyDAEIDTRLPVPAVEPHLPRVER-----ALDMLLAAERPLILAGGGVILADAGSELRELVEELRVPFQ 231
Cdd:PRK06456 161 DIPRDIFYEKME-EIKWPEKPLVKGYRDFPTRIDRlalkkAAEILINAERPIILVGTGVVWSNATPEVLELAELLHIPIV 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 232 VTLMGKGVIEDDHELNLGTTGIQtSQRYANASFLESDFVLAVGARFGDRHTGANIDIYRGERTFVHVDIEPAQIGKVFEP 311
Cdd:PRK06456 240 STFPGKTAIPHDHPLYFGPMGYY-GRAEASMAALESDAMLVVGARFSDRTFTSYDEMVETRKKFIMVNIDPTDGEKAIKV 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 312 DLGIVSDAGLFLTALLAEARKRKARADVGSWVERCQELKRTLVRREDFDSTPVKAP-RAYKEINEAFDENTYFVTAIGLY 390
Cdd:PRK06456 319 DVGIYGNAKIILRELIKAITELGQKRDRSAWLKRVKEYKEYYSQFYYTEENGKLKPwKIMKTIRQALPRDAIVTTGVGQH 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 391 QIWGGQHQKAYLPRHYQVCGQAGPLGWEVPAAIGVKkalegMGEPDAEVVGIVGDYGFQYLVEELAVAAQYNVPYVLIML 470
Cdd:PRK06456 399 QMWAEVFWEVLEPRTFLTSSGMGTMGFGLPAAMGAK-----LARPDKVVVDLDGDGSFLMTGTNLATAVDEHIPVISVIF 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 471 NNEYLGLIRQAEIGYGMNYQVDIHYDEfGTDNVKLMEAYGCSGQRVWEPADISGAIQWARKEAVatsrPVLVEIMIEREA 550
Cdd:PRK06456 474 DNRTLGLVRQVQDLFFGKRIVGVDYGP-SPDFVKLAEAFGALGFNVTTYEDIEKSLKSAIKEDI----PAVIRVPVDKEE 548
|
|
| PRK08322 |
PRK08322 |
acetolactate synthase large subunit; |
4-546 |
2.86e-104 |
|
acetolactate synthase large subunit;
Pssm-ID: 236239 [Multi-domain] Cd Length: 547 Bit Score: 324.47 E-value: 2.86e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 4 MNAA---VSIMVDEGVDIAFGCPGAAILPLYKAMEeDGRIDHLTVRHEEGATHMADGWARTNGKVGVAIATSGPGATNLV 80
Cdd:PRK08322 1 MKAAdlfVKCLENEGVEYIFGIPGEENLDLLEALR-DSSIKLILTRHEQGAAFMAATYGRLTGKAGVCLSTLGPGATNLV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 81 TGLYTAQADSIPMVCLTGQAVSPKLHQEAFQAVDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAGRPGPVLIDLPL 160
Cdd:PRK08322 80 TGVAYAQLGGMPMVAITGQKPIKRSKQGSFQIVDVVAMMAPLTKWTRQIVSPDNIPEVVREAFRLAEEERPGAVHLELPE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 161 DLAKREitYDAEIDTRLPVPAVEPHLPRVERALDMLLAAERPLILAGGGVILADAGSELRELVEELRVPFQVTLMGKGVI 240
Cdd:PRK08322 160 DIAAEE--TDGKPLPRSYSRRPYASPKAIERAAEAIQAAKNPLILIGAGANRKTASKALTEFVDKTGIPFFTTQMGKGVI 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 241 EDDHELNLGTTGIqtSQR-YANASFLESDFVLAVG-------ARFGDRHtganidiyrGERTFVHVDIEPAQIGKVFEPD 312
Cdd:PRK08322 238 PETHPLSLGTAGL--SQGdYVHCAIEHADLIINVGhdviekpPFFMNPN---------GDKKVIHINFLPAEVDPVYFPQ 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 313 LGIVSDAGLFLTALLAEARKRKARADVGSWVERcQELKRTLVRREDFDSTPVKAPRAYKEINEAFDENTYFVTAIGLYQI 392
Cdd:PRK08322 307 VEVVGDIANSLWQLKERLADQPHWDFPRFLKIR-EAIEAHLEEGADDDRFPMKPQRIVADLRKVMPDDDIVILDNGAYKI 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 393 WGGQHQKAYLPrhyQVC----GQAGpLGWEVPAAIGVKkalegMGEPDAEVVGIVGDYGFQYLVEELAVAAQYNVPYVLI 468
Cdd:PRK08322 386 WFARNYRAYEP---NTClldnALAT-MGAGLPSAIAAK-----LVHPDRKVLAVCGDGGFMMNSQELETAVRLGLPLVVL 456
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 469 MLNNEYLGLIR--QAEIgYGMNYQVDihydeFGT-DNVKLMEAYGCSGQRVWEPADISGAIqwarKEAVATSRPVLVEIM 545
Cdd:PRK08322 457 ILNDNAYGMIRwkQENM-GFEDFGLD-----FGNpDFVKYAESYGAKGYRVESADDLLPTL----EEALAQPGVHVIDCP 526
|
.
gi 1941825792 546 I 546
Cdd:PRK08322 527 V 527
|
|
| PLN02470 |
PLN02470 |
acetolactate synthase |
14-554 |
2.96e-103 |
|
acetolactate synthase
Pssm-ID: 215261 [Multi-domain] Cd Length: 585 Bit Score: 323.23 E-value: 2.96e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 14 EGVDIAFGCPGAAILPLYKAMEEDGRIDHLTVRHEEGATHMADGWARTNGKVGVAIATSGPGATNLVTGLYTAQADSIPM 93
Cdd:PLN02470 26 EGVDTVFAYPGGASMEIHQALTRSNCIRNVLCRHEQGEVFAAEGYAKASGKVGVCIATSGPGATNLVTGLADALLDSVPL 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 94 VCLTGQAVSPKLHQEAFQAVDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAGRPGPVLIDLPLDLAKR-------- 165
Cdd:PLN02470 106 VAITGQVPRRMIGTDAFQETPIVEVTRSITKHNYLVMDVEDIPRVIREAFFLASSGRPGPVLVDIPKDIQQQlavpnwnq 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 166 EITYDAEIdTRLPVPAVEPHLprvERALDMLLAAERPLILAGGGVIlaDAGSELRELVEELRVPFQVTLMGKGVIEDDHE 245
Cdd:PLN02470 186 PMKLPGYL-SRLPKPPEKSQL---EQIVRLISESKRPVVYVGGGCL--NSSEELREFVELTGIPVASTLMGLGAFPASDE 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 246 LNLGTTGIQTSQrYANASFLESDFVLAVGARFGDRHTGaNIDIYRGERTFVHVDIEPAQIGKVFEPDLGIVSDAGLFLTA 325
Cdd:PLN02470 260 LSLQMLGMHGTV-YANYAVDSADLLLAFGVRFDDRVTG-KLEAFASRASIVHIDIDPAEIGKNKQPHVSVCADVKLALQG 337
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 326 L--LAEARKRKaRADVGSWvercqelkrtlvrREDFDSTPVKAPRAYKEINEA---------FDE----NTYFVTAIGLY 390
Cdd:PLN02470 338 LnkLLEERKAK-RPDFSAW-------------RAELDEQKEKFPLSYPTFGDAippqyaiqvLDEltdgNAIISTGVGQH 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 391 QIWGGQHQKAYLPRHYQVCGQAGPLGWEVPAAIGVKKAlegmgEPDAEVVGIVGDYGFQYLVEELAVAAQYNVPYVLIML 470
Cdd:PLN02470 404 QMWAAQWYKYKEPRRWLTSGGLGAMGFGLPAAIGAAAA-----NPDAIVVDIDGDGSFIMNIQELATIHVENLPVKIMVL 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 471 NNEYLGLIRQAEIGY-----GMNYQVD-IHYDEFGTDNVKLMEAYGCSGQRVWEPADISGAIQwarkEAVATSRPVLVEI 544
Cdd:PLN02470 479 NNQHLGMVVQWEDRFykanrAHTYLGDpDAEAEIFPDFLKFAEGCKIPAARVTRKSDLREAIQ----KMLDTPGPYLLDV 554
|
570
....*....|
gi 1941825792 545 MIereantPH 554
Cdd:PLN02470 555 IV------PH 558
|
|
| PRK08199 |
PRK08199 |
thiamine pyrophosphate protein; Validated |
1-563 |
1.56e-93 |
|
thiamine pyrophosphate protein; Validated
Pssm-ID: 181285 [Multi-domain] Cd Length: 557 Bit Score: 296.79 E-value: 1.56e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 1 MPAMNAAVSIMVD----EGVDIAFGCPGAAILPLYKAMEEDGRIDHLTVRHEEGATHMADGWARTNGKVGVAIATSGPGA 76
Cdd:PRK08199 4 TPRARTGGQILVDalraNGVERVFCVPGESYLAVLDALHDETDIRVIVCRQEGGAAMMAEAYGKLTGRPGICFVTRGPGA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 77 TNLVTGLYTAQADSIPMVCLTGQAVSPKLHQEAFQAVDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAGRPGPVLI 156
Cdd:PRK08199 84 TNASIGVHTAFQDSTPMILFVGQVARDFREREAFQEIDYRRMFGPMAKWVAEIDDAARIPELVSRAFHVATSGRPGPVVL 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 157 DLPLDLakreITYDAEIDTRLPVPAVEPHlPR---VERALDMLLAAERPLILAGGGVILADAGSELRELVEELRVPFQVT 233
Cdd:PRK08199 164 ALPEDV----LSETAEVPDAPPYRRVAAA-PGaadLARLAELLARAERPLVILGGSGWTEAAVADLRAFAERWGLPVACA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 234 LMGKGVIEDDHELNLGTTGIQTSQRYAnASFLESDFVLAVGARFGDRHTG--ANIDIYRGERTFVHVDIEPAQIGKVFEP 311
Cdd:PRK08199 239 FRRQDLFDNRHPNYAGDLGLGINPALA-ARIREADLVLAVGTRLGEVTTQgyTLLDIPVPRQTLVHVHPDAEELGRVYRP 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 312 DLGIVSDAGLFLTALLA-EARKRKARADvgsWVERcqelkrtlvRREDFD--STPVKAP------RAYKEINEAFDENTY 382
Cdd:PRK08199 318 DLAIVADPAAFAAALAAlEPPASPAWAE---WTAA---------AHADYLawSAPLPGPgavqlgEVMAWLRERLPADAI 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 383 FVTAIGLYQIWggqhqkayLPRHYQ---VCGQAGP----LGWEVPAAIGVKKAlegmgEPDAEVVGIVGDYGFQYLVEEL 455
Cdd:PRK08199 386 ITNGAGNYATW--------LHRFFRfrrYRTQLAPtsgsMGYGLPAAIAAKLL-----FPERTVVAFAGDGCFLMNGQEL 452
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 456 AVAAQYNVPYVLIMLNNEYLGLIRqaeigygMnYQvDIHYDE--FGTD--N---VKLMEAYGCSGQRVWEPADISGAIQW 528
Cdd:PRK08199 453 ATAVQYGLPIIVIVVNNGMYGTIR-------M-HQ-EREYPGrvSGTDltNpdfAALARAYGGHGETVERTEDFAPAFER 523
|
570 580 590
....*....|....*....|....*....|....*
gi 1941825792 529 ARkeavATSRPVLVEIMIEREANTPhGPDIDAVRE 563
Cdd:PRK08199 524 AL----ASGKPALIEIRIDPEAITP-TATLSQIRE 553
|
|
| PRK08266 |
PRK08266 |
hypothetical protein; Provisional |
1-549 |
2.41e-90 |
|
hypothetical protein; Provisional
Pssm-ID: 181337 [Multi-domain] Cd Length: 542 Bit Score: 288.06 E-value: 2.41e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 1 MPAMN---AAVSIMVDEGVDIAFGCPGAAILPLYKAM-EEDGRIDHLTVRHEEGATHMADGWARTNGKVGVAIATSGPGA 76
Cdd:PRK08266 1 MTTMTggeAIVAGLVAHGVDTVFGLPGAQLYWLFDALyKAGDRIRVIHTRHEQAAGYMAFGYARSTGRPGVCSVVPGPGV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 77 TNLVTGLYTAQADSIPMVCLTGQAVSP-------KLHQEAFQavdiVEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAG 149
Cdd:PRK08266 81 LNAGAALLTAYGCNSPVLCLTGQIPSAligkgrgHLHEMPDQ----LATLRSFTKWAERIEHPSEAPALVAEAFQQMLSG 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 150 RPGPVLIDLPLD-LAKREITYDAEIDTRLPVPAVEPHlpRVERALDMLLAAERPLILAGGGVilADAGSELRELVEELRV 228
Cdd:PRK08266 157 RPRPVALEMPWDvFGQRAPVAAAPPLRPAPPPAPDPD--AIAAAAALIAAAKNPMIFVGGGA--AGAGEEIRELAEMLQA 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 229 PFQVTLMGKGVIEDDHELNLGTTGiqtsqryANASFLESDFVLAVGARFGDRHTGANidiYRGER-TFVHVDIEPAQIGK 307
Cdd:PRK08266 233 PVVAFRSGRGIVSDRHPLGLNFAA-------AYELWPQTDVVIGIGSRLELPTFRWP---WRPDGlKVIRIDIDPTEMRR 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 308 vFEPDLGIVSDAGLFLTALLAEARKRKARADvgswvERCQELkRTLVRREDFDSTPVKAPRAY-KEINEAFDENTYFV-- 384
Cdd:PRK08266 303 -LKPDVAIVADAKAGTAALLDALSKAGSKRP-----SRRAEL-RELKAAARQRIQAVQPQASYlRAIREALPDDGIFVde 375
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 385 -TAIGlYQIWGGqhQKAYLPRHYQVCGQAGPLGWEVPAAIGVKkalegMGEPDAEVVGIVGDYGFQYLVEELAVAAQYNV 463
Cdd:PRK08266 376 lSQVG-FASWFA--FPVYAPRTFVTCGYQGTLGYGFPTALGAK-----VANPDRPVVSITGDGGFMFGVQELATAVQHNI 447
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 464 PYVLIMLNNEYLGLIR--QAEIGYGMNYQVDIHYDEFgtdnVKLMEAYGCSGQRVWEPADISGAIqwarKEAVATSRPVL 541
Cdd:PRK08266 448 GVVTVVFNNNAYGNVRrdQKRRFGGRVVASDLVNPDF----VKLAESFGVAAFRVDSPEELRAAL----EAALAHGGPVL 519
|
....*...
gi 1941825792 542 VEIMIERE 549
Cdd:PRK08266 520 IEVPVPRG 527
|
|
| PRK06112 |
PRK06112 |
acetolactate synthase catalytic subunit; Validated |
1-553 |
6.33e-85 |
|
acetolactate synthase catalytic subunit; Validated
Pssm-ID: 235700 [Multi-domain] Cd Length: 578 Bit Score: 275.10 E-value: 6.33e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 1 MPAMNAAVSIMVDEGVDIAFG--CPGAAILplykAMEEDGrIDHLTVRHEEGATHMADGWARTNGKVGVAIATSGPGATN 78
Cdd:PRK06112 14 GTVAHAIARALKRHGVEQIFGqsLPSALFL----AAEAIG-IRQIAYRTENAGGAMADGYARVSGKVAVVTAQNGPAATL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 79 LVTGLYTAQADSIPMVCLTGQAVSPKLHQEAFQAVDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAGRPGPVLIDL 158
Cdd:PRK06112 89 LVAPLAEALKASVPIVALVQDVNRDQTDRNAFQELDHIALFQSCTKWVRRVTVAERIDDYVDQAFTAATSGRPGPVVLLL 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 159 PLDLAKREITYDAEIDT----RLPVPAVEPHLPRVERALDMLLAAERPLILAGGGVILADAGSELRELVEELRVPFQVTL 234
Cdd:PRK06112 169 PADLLTAAAAAPAAPRSnslgHFPLDRTVPAPQRLAEAASLLAQAQRPVVVAGGGVHISGASAALAALQSLAGLPVATTN 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 235 MGKGVIEDDHELNLGT----TGIQTSQRYANASFLESDFVLAVGARFGDRHTgANIDIYRGERTFVHVDIEPAQIGKVFE 310
Cdd:PRK06112 249 MGKGAVDETHPLSLGVvgslMGPRSPGRHLRDLVREADVVLLVGTRTNQNGT-DSWSLYPEQAQYIHIDVDGEEVGRNYE 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 311 PdLGIVSDAGLFLTALLAE------ARKRKARADVGSWVERCQELKRTLVRR-EDFDSTPVKAPRAYKEINEAFDENTYF 383
Cdd:PRK06112 328 A-LRLVGDARLTLAALTDAlrgrdlAARAGRRAALEPAIAAGREAHREDSAPvALSDASPIRPERIMAELQAVLTGDTIV 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 384 VTAIGLYQIWGGQHQKAYLPRHYQVC--GQAGpLGWEVPAAIGVKKAlegmgEPDAEVVGIVGDYGFQYLVEELAVAAQY 461
Cdd:PRK06112 407 VADASYSSIWVANFLTARRAGMRFLTprGLAG-LGWGVPMAIGAKVA-----RPGAPVICLVGDGGFAHVWAELETARRM 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 462 NVPYVLIMLNNEYLGLIRQAEIGYGMNYQVDIHYDEfgTDNVKLMEAYGCSGQRVWEPADISGAIQWARKEAVatsrPVL 541
Cdd:PRK06112 481 GVPVTIVVLNNGILGFQKHAETVKFGTHTDACHFAA--VDHAAIARACGCDGVRVEDPAELAQALAAAMAAPG----PTL 554
|
570
....*....|..
gi 1941825792 542 VEIMIEREANTP 553
Cdd:PRK06112 555 IEVITDPSAFPP 566
|
|
| PRK08611 |
PRK08611 |
pyruvate oxidase; Provisional |
3-550 |
1.48e-81 |
|
pyruvate oxidase; Provisional
Pssm-ID: 181502 [Multi-domain] Cd Length: 576 Bit Score: 266.10 E-value: 1.48e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 3 AMNAAVSIMVDEGVDIAFGCPGAAILPLYKAM--EEDgRIDHLTVRHEEGATHMADGWARTNGKVGVAIATSGPGATNLV 80
Cdd:PRK08611 6 AGEALVKLLQDWGIDHVYGIPGDSIDAVVDALrkEQD-KIKFIQVRHEEVAALAAAAYAKLTGKIGVCLSIGGPGAIHLL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 81 TGLYTAQADSIPMVCLTGQAVSPKLHQEAFQAVDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAGRPGPVLIdLPL 160
Cdd:PRK08611 85 NGLYDAKMDHVPVLALAGQVTSDLLGTDFFQEVNLEKMFEDVAVYNHQIMSAENLPEIVNQAIRTAYEKKGVAVLT-IPD 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 161 DLAKREI--TYDAEIDTRLPvPAVEPHLPRVERALDMLLAAERPLILAGGGviLADAGSELRELVEELRVPFQVTLMGKG 238
Cdd:PRK08611 164 DLPAQKIkdTTNKTVDTFRP-TVPSPKPKDIKKAAKLINKAKKPVILAGLG--AKHAKEELLAFAEKAKIPIIHTLPAKG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 239 VIEDDHELNLGTTG-IQTSQRYanASFLESDFVLAVGARFGdrhtganidiYRG----ERTFVHVDIEPAQIGKVFEPDL 313
Cdd:PRK08611 241 IIPDDHPYSLGNLGkIGTKPAY--EAMQEADLLIMVGTNYP----------YVDylpkKAKAIQIDTDPANIGKRYPVNV 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 314 GIVSDAGLFLTALLAEARKRKARadvgSWVERCQELKRT----LVRREDFDSTPVKAPRAYKEINEAFDENTYFVTAIGL 389
Cdd:PRK08611 309 GLVGDAKKALHQLTENIKHVEDR----RFLEACQENMAKwwkwMEEDENNASTPIKPERVMAAIQKIADDDAVLSVDVGT 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 390 YQIWGGQHQKAYLPRHYQVCGQAGPLGWEVPAAIGVKKAlegmgEPDAEVVGIVGDYGFQYLVEELAVAAQYNVPYVLIM 469
Cdd:PRK08611 385 VTVWSARYLNLGTNQKFIISSWLGTMGCGLPGAIAAKIA-----FPDRQAIAICGDGGFSMVMQDFVTAVKYKLPIVVVV 459
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 470 LNNEYLGLIR--QAEIGYgMNYQVDIHYDEFGtdnvKLMEAYGCSGQRVWEPADISGAIQwarkEAVATSRPVLVEIMIE 547
Cdd:PRK08611 460 LNNQQLAFIKyeQQAAGE-LEYAIDLSDMDYA----KFAEACGGKGYRVEKAEELDPAFE----EALAQDKPVIIDVYVD 530
|
...
gi 1941825792 548 REA 550
Cdd:PRK08611 531 PNA 533
|
|
| PRK07524 |
PRK07524 |
5-guanidino-2-oxopentanoate decarboxylase; |
6-544 |
1.01e-79 |
|
5-guanidino-2-oxopentanoate decarboxylase;
Pssm-ID: 236041 [Multi-domain] Cd Length: 535 Bit Score: 260.29 E-value: 1.01e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 6 AAVSIMVDEGVDIAFGCPGAAILPLYKAMEeDGRIDHLTVRHEEGATHMADGWARTNGKVGVAIATSGPGATNLVTGLYT 85
Cdd:PRK07524 7 ALVRLLEAYGVETVFGIPGVHTVELYRGLA-GSGIRHVTPRHEQGAGFMADGYARVSGKPGVCFIITGPGMTNIATAMGQ 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 86 AQADSIPMVCLTG-QAVSP------KLHQEAFQAvdivEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAGRPGPVLIDL 158
Cdd:PRK07524 86 AYADSIPMLVISSvNRRASlgkgrgKLHELPDQR----AMVAGVAAFSHTLMSAEDLPEVLARAFAVFDSARPRPVHIEI 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 159 PLDLAKREITYDAEIDTRLPVPAvEPHLPRVERALDMLLAAERPLILAGGGVIlaDAGSELRELVEELRVPFQVTLMGKG 238
Cdd:PRK07524 162 PLDVLAAPADHLLPAPPTRPARP-GPAPAALAQAAERLAAARRPLILAGGGAL--AAAAALRALAERLDAPVALTINAKG 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 239 VIEDDHELNLGTTgiqTSQRYANASFLESDFVLAVGARFGDrhtgANIDIYRGER-----TFVHVDIEPAQIGKVFEPDL 313
Cdd:PRK07524 239 LLPAGHPLLLGAS---QSLPAVRALIAEADVVLAVGTELGE----TDYDVYFDGGfplpgELIRIDIDPDQLARNYPPAL 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 314 GIVSDAGLFLTALLAEARKRKARADVGSwvERCQELKRTLvrREDFDSTPVKAPRAYKEINEAFDENTyFVtaiglyqiw 393
Cdd:PRK07524 312 ALVGDARAALEALLARLPGQAAAADWGA--ARVAALRQAL--RAEWDPLTAAQVALLDTILAALPDAI-FV--------- 377
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 394 GGQHQKAYLPRHYQVCGQA----------GPLGWEVPAAIGVKkalegMGEPDAEVVGIVGDYGFQYLVEELAVAAQYNV 463
Cdd:PRK07524 378 GDSTQPVYAGNLYFDADAPrrwfnastgyGTLGYGLPAAIGAA-----LGAPERPVVCLVGDGGLQFTLPELASAVEADL 452
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 464 PYVLIMLNNEYLGLIRQAEIGYGMN-YQVDIHYDEFgtdnVKLMEAYGCSGQRVwepADIsGAIQWARKEAVATSRPVLV 542
Cdd:PRK07524 453 PLIVLLWNNDGYGEIRRYMVARDIEpVGVDPYTPDF----IALARAFGCAAERV---ADL-EQLQAALRAAFARPGPTLI 524
|
..
gi 1941825792 543 EI 544
Cdd:PRK07524 525 EV 526
|
|
| pyruv_oxi_spxB |
TIGR02720 |
pyruvate oxidase; Members of this family are examples of pyruvate oxidase (EC 1.2.3.3), an ... |
15-546 |
4.14e-74 |
|
pyruvate oxidase; Members of this family are examples of pyruvate oxidase (EC 1.2.3.3), an enzyme with FAD and TPP as cofactors that catalyzes the reaction pyruvate + phosphate + O2 + H2O = acetyl phosphate + CO2 + H2O2. It should not be confused with pyruvate dehydrogenase [cytochrome] (EC 1.2.2.2) as in E. coli PoxB, although the E. coli enzyme is closely homologous and has pyruvate oxidase as an alternate name. [Energy metabolism, Aerobic]
Pssm-ID: 213733 [Multi-domain] Cd Length: 575 Bit Score: 246.67 E-value: 4.14e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 15 GVDIAFGCPGAAILPLYKAMEED-GRIDHLTVRHEEGATHMADGWARTNGKVGVAIATSGPGATNLVTGLYTAQADSIPM 93
Cdd:TIGR02720 13 GVDHIYGIPGGSFNSTMDALSAErDRIHYIQVRHEEVGALAAAADAKLTGKIGVCFGSAGPGATHLLNGLYDAKEDHVPV 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 94 VCLTGQAVSPKLHQEAFQAVDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAgRPGPVLIDLPLDLAKREIT----Y 169
Cdd:TIGR02720 93 LALVGQVPTTGMNMDTFQEMNENPIYADVAVYNRTAMTAESLPHVIDEAIRRAYA-HNGVAVVTIPVDFGWQEIPdndyY 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 170 DAEIDTRLPVpAVEPHLPRVERALDMLLAAERPLILAGGGVIlaDAGSELRELVEELRVPFQVTLMGKGVIEDDHELNLG 249
Cdd:TIGR02720 172 ASSVSYQTPL-LPAPDVEAVTRAVQTLKAAERPVIYYGIGAR--KAGEELEALSEKLKIPLISTGLAKGIIEDRYPAYLG 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 250 TTGiQTSQRYANASFLESDFVLAVGARFGDRHTGANidiYRGERTFVHVDIEPAQIGKVFEPDLGIVSDAGLFLTALLA- 328
Cdd:TIGR02720 249 SAY-RVAQKPANEALFQADLVLFVGNNYPFAEVSKA---FKNTKYFIQIDIDPAKLGKRHHTDIAVLADAKKALAAILAq 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 329 -EARK-----RKARADVGSWvercqelKRTLVRREDFDSTPVKAPRAYKEINEAFDENTYFVTAIGLYQIWGGQHQKAYL 402
Cdd:TIGR02720 325 vEPREstpwwQANVANVKNW-------RAYLASLEDKTEGPLQAYQVYRAINKIAEDDAIYSIDVGDININSNRHLKMTP 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 403 PRHYQVCGQAGPLGWEVPAAIGVKkalegMGEPDAEVVGIVGDYGFQYLVEELAVAAQYNVPYVLIMLNNEYLGLIRqae 482
Cdd:TIGR02720 398 KNKWITSNLFATMGVGVPGAIAAK-----LNYPDRQVFNLAGDGAFSMTMQDLLTQVQYHLPVINIVFSNCTYGFIK--- 469
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1941825792 483 igygmNYQVDIHYDEFG-----TDNVKLMEAYGCSGQRVWEPADISGAIQWARKeaVATSRPVLVEIMI 546
Cdd:TIGR02720 470 -----DEQEDTNQPLIGvdfndADFAKIAEGVGAVGFRVNKIEQLPAVFEQAKA--IKQGKPVLIDAKI 531
|
|
| sulphoacet_xsc |
TIGR03457 |
sulfoacetaldehyde acetyltransferase; Members of this protein family are sulfoacetaldehyde ... |
1-553 |
2.57e-72 |
|
sulfoacetaldehyde acetyltransferase; Members of this protein family are sulfoacetaldehyde acetyltransferase, an enzyme of taurine utilization. Taurine, or 2-aminoethanesulfonate, can be used by bacteria as a source of carbon, nitrogen, and sulfur. [Central intermediary metabolism, Other]
Pssm-ID: 132497 [Multi-domain] Cd Length: 579 Bit Score: 242.08 E-value: 2.57e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 1 MPAMNAAVSIMVDEGVDIAFGCPGAAILPLYKAMEEDGrIDHLTVRHEEGATHMADGWARTNGKVGVAIATSGPGATNLV 80
Cdd:TIGR03457 2 MTPSEAFVEVLVANGVTHAFGIMGSAFMDAMDLFPPAG-IRFIPVVHEQGAGHMADGFARVTGRMSMVIGQNGPGVTNCV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 81 TGLYTAQADSIPMVCLTGQAVSPKLHQEAFQAVDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAGRpGPVLIDLPL 160
Cdd:TIGR03457 81 TAIAAAYWAHTPVVIVTPEAGTKTIGLGGFQEADQLPMFQEFTKYQGHVRHPSRMAEVLNRCFERAWREM-GPAQLNIPR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 161 DLAKREITYDAEIDTRLPVPAVEPhlPRVERALDMLLAAERPLILAGGGVILADAGSELRELVEELRVPFQVTLMGKGVI 240
Cdd:TIGR03457 160 DYFYGEIDVEIPRPVRLDRGAGGA--TSLAQAARLLAEAKFPVIISGGGVVMGDAVEECKALAERLGAPVVNSYLHNDSF 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 241 EDDHELNLGTTGIQTSqRYANASFLESDFVLAVGARFGDRHT--GANIDIYRGERTFVHVDIEPAQIGKVFEPDLGIVSD 318
Cdd:TIGR03457 238 PASHPLWVGPLGYQGS-KAAMKLISDADVVLALGTRLGPFGTlpQYGIDYWPKNAKIIQVDANAKMIGLVKKVTVGICGD 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 319 AGLFLTALLA-----------EARKRKARADVGSWVercQELKRTLVRREDF-----------DSTPVKAPRAYKEINEA 376
Cdd:TIGR03457 317 AKAAAAEILQrlagkagdanrAERKAKIQAERSAWE---QELSEMTHERDPFsldmiveqrqeEGNWLHPRQVLRELEKA 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 377 FDENTYFVTAIGLYQIWGGQHQKAYLPRHYQVCGQAGPLGWEVPAAIGVKkalegMGEPDAEVVGIVGDYGFQYLVEELA 456
Cdd:TIGR03457 394 MPEDAIVSTDIGNINSVANSYLRFEKPRKFLAPMSFGNCGYAFPTIIGAK-----IAAPDRPVVAYAGDGAWGMSMNEIM 468
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 457 VAAQYNVPYVLIMLNNEYLGlirqAEigygMNYQVDIHYDEF-GTD------NVKLMEAYGCSGQRVWEPADISGAIQWA 529
Cdd:TIGR03457 469 TAVRHDIPVTAVVFRNRQWG----AE----KKNQVDFYNNRFvGTEleselsFAGIADAMGAKGVVVDKPEDVGPALKKA 540
|
570 580
....*....|....*....|....
gi 1941825792 530 rKEAVATSRPVLVEIMIEREANTP 553
Cdd:TIGR03457 541 -IAAQAEGKTTVIEIVCTRELGDP 563
|
|
| PRK07525 |
PRK07525 |
sulfoacetaldehyde acetyltransferase; Validated |
1-553 |
1.32e-69 |
|
sulfoacetaldehyde acetyltransferase; Validated
Pssm-ID: 236042 [Multi-domain] Cd Length: 588 Bit Score: 234.89 E-value: 1.32e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 1 MPAMN---AAVSIMVDEGVDIAFGCPGAAILPLYKAMEEDGrIDHLTVRHEEGATHMADGWARTNGKVGVAIATSGPGAT 77
Cdd:PRK07525 3 KMKMTpseAFVETLQAHGITHAFGIIGSAFMDASDLFPPAG-IRFIDVAHEQNAGHMADGYTRVTGRMGMVIGQNGPGIT 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 78 NLVTGLYTAQADSIPMVCLTGQAVSPKLHQEAFQAVDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAGRpGPVLID 157
Cdd:PRK07525 82 NFVTAVATAYWAHTPVVLVTPQAGTKTIGQGGFQEAEQMPMFEDMTKYQEEVRDPSRMAEVLNRVFDKAKRES-GPAQIN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 158 LPLDLakreitYDAEIDTRLPVPavePHLPR-------VERALDMLLAAERPLILAGGGVILADAGSELRELVEELRVPF 230
Cdd:PRK07525 161 IPRDY------FYGVIDVEIPQP---VRLERgaggeqsLAEAAELLSEAKFPVILSGAGVVLSDAIEECKALAERLDAPV 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 231 QVTLMGKGVIEDDHELNLGTTGIQTSqRYANASFLESDFVLAVGARFGDRHT--GANIDIYRGERTFVHVDIEPAQIGKV 308
Cdd:PRK07525 232 ACGYLHNDAFPGSHPLWVGPLGYNGS-KAAMELIAKADVVLALGTRLNPFGTlpQYGIDYWPKDAKIIQVDINPDRIGLT 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 309 FEPDLGIVSDAGLFLTALLA------------EARKRKARADVGSWVercQELKRTLVRREDFDSTPVK----------A 366
Cdd:PRK07525 311 KKVSVGICGDAKAVARELLArlaerlagdagrEERKALIAAEKSAWE---QELSSWDHEDDDPGTDWNEeararkpdymH 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 367 PR-AYKEINEAFDENTYFVTAIGLYQIWGgqhqKAYL----PRHYQVCGQAGPLGWEVPAAIGVKkalegMGEPDAEVVG 441
Cdd:PRK07525 388 PRqALREIQKALPEDAIVSTDIGNNCSIA----NSYLrfekGRKYLAPGSFGNCGYAFPAIIGAK-----IACPDRPVVG 458
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 442 IVGDYGFQYLVEELAVAAQYNVPYVLIMLNNEYLGlirqAEigygMNYQVDIHYDEF-GTD------NVKLMEAYGCSGQ 514
Cdd:PRK07525 459 FAGDGAWGISMNEVMTAVRHNWPVTAVVFRNYQWG----AE----KKNQVDFYNNRFvGTEldnnvsYAGIAEAMGAEGV 530
|
570 580 590
....*....|....*....|....*....|....*....
gi 1941825792 515 RVWEPADISGAIQWARkEAVATSRPVLVEIMIEREANTP 553
Cdd:PRK07525 531 VVDTQEELGPALKRAI-DAQNEGKTTVIEIMCNQELGEP 568
|
|
| PRK08617 |
PRK08617 |
acetolactate synthase AlsS; |
15-544 |
3.74e-69 |
|
acetolactate synthase AlsS;
Pssm-ID: 236312 [Multi-domain] Cd Length: 552 Bit Score: 232.82 E-value: 3.74e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 15 GVDIAFGCPGAAILPLYKAMEEDGrIDHLTVRHEEGATHMADGWARTNGKVGVAIATSGPGATNLVTGLYTAQADSIPMV 94
Cdd:PRK08617 19 GVKYVFGIPGAKIDRVFDALEDSG-PELIVTRHEQNAAFMAAAIGRLTGKPGVVLVTSGPGVSNLATGLVTATAEGDPVV 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 95 CLTGQAVSPKLHQEAFQAVDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAGRPGPVLIDLPLDLAKREITYDAEID 174
Cdd:PRK08617 98 AIGGQVKRADRLKRTHQSMDNVALFRPITKYSAEVQDPDNLSEVLANAFRAAESGRPGAAFVSLPQDVVDAPVTSKAIAP 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 175 TRLPVPAVePHLPRVERALDMLLAAERPLILAGGGVILADAGSELRELVEELRVPFQVTLMGKGVIEDDHELN-LGTTGI 253
Cdd:PRK08617 178 LSKPKLGP-ASPEDINYLAELIKNAKLPVLLLGMRASSPEVTAAIRRLLERTNLPVVETFQAAGVISRELEDHfFGRVGL 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 254 ---QTSQRYANasflESDFVLAVG-------ARFGDRHtganidiyrGERTFVHVDIEPAQIGKVFEPDLGIVSDAGLFL 323
Cdd:PRK08617 257 frnQPGDELLK----KADLVITIGydpieyePRNWNSE---------GDATIIHIDVLPAEIDNYYQPERELIGDIAATL 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 324 TALLAEARK----RKARADVGswvERCQELKRTLVRREDFDSTPVKAPRAYKEINEAFDENTYFVTAIGLYQIWGGQHQK 399
Cdd:PRK08617 324 DLLAEKLDGlslsPQSLEILE---ELRAQLEELAERPARLEEGAVHPLRIIRALQDIVTDDTTVTVDVGSHYIWMARYFR 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 400 AYLPRHYQVCGQAGPLGWEVPAAIGVkkaleGMGEPDAEVVGIVGDYGFQYLVEELAVAAQYNVPYVLIMLNNEYLGLIR 479
Cdd:PRK08617 401 SYEPRHLLFSNGMQTLGVALPWAIAA-----ALVRPGKKVVSVSGDGGFLFSAMELETAVRLKLNIVHIIWNDGHYNMVE 475
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1941825792 480 -QAEIGYGMNYQVDihydeFG-TDNVKLMEAYGCSGQRVWEPADISGAIqwarKEAVATSRPVLVEI 544
Cdd:PRK08617 476 fQEEMKYGRSSGVD-----FGpVDFVKYAESFGAKGLRVTSPDELEPVL----REALATDGPVVIDI 533
|
|
| PRK06154 |
PRK06154 |
thiamine pyrophosphate-requiring protein; |
1-549 |
4.85e-69 |
|
thiamine pyrophosphate-requiring protein;
Pssm-ID: 235718 [Multi-domain] Cd Length: 565 Bit Score: 232.78 E-value: 4.85e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 1 MPAMNAAVSIMVDEGVDIAFGCPgaaILPLYKAMEEDGrIDHLTVRHEEGATHMADGWAR-TNGK-VGVAIATSGPGATN 78
Cdd:PRK06154 20 MKVAEAVAEILKEEGVELLFGFP---VNELFDAAAAAG-IRPVIARTERVAVHMADGYARaTSGErVGVFAVQYGPGAEN 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 79 LVTGLYTAQADSIPMVCLTG------QAVSPKlhqeaFQAVdivEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAGRPG 152
Cdd:PRK06154 96 AFGGVAQAYGDSVPVLFLPTgyprgsTDVAPN-----FESL---RNYRHITKWCEQVTLPDEVPELMRRAFTRLRNGRPG 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 153 PVLIDLPLDLAKREITyDAEIDTRlPVPAVEPHL-PR-VERALDMLLAAERPLILAGGGVILADAGSELRELVEELRVPF 230
Cdd:PRK06154 168 PVVLELPVDVLAEELD-ELPLDHR-PSRRSRPGAdPVeVVEAAALLLAAERPVIYAGQGVLYAQATPELKELAELLEIPV 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 231 QVTLMGKGVIEDDHELNLGTTGIqtSQRYANASFL-ESDFVLAVGARFGDRHTGANIDiyrGERTFVHVDIEPAQIGKVF 309
Cdd:PRK06154 246 MTTLNGKSAFPEDHPLALGSGGR--ARPATVAHFLrEADVLFGIGCSLTRSYYGLPMP---EGKTIIHSTLDDADLNKDY 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 310 EPDLGIVSDAGLFLTALLAEARKR-----KARADVGSWVERC-QELKRTLVRREDFDSTPVKAPRAYKEINEAFDENTYF 383
Cdd:PRK06154 321 PIDHGLVGDAALVLKQMIEELRRRvgpdrGRAQQVAAEIEAVrAAWLAKWMPKLTSDSTPINPYRVVWELQHAVDIKTVI 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 384 VTAIG------LYQIWggqhqKAYLPRHYQVCGQAGPLGWEVPAAIGVKkalegMGEPDAEVVGIVGDYGFQYLVEELAV 457
Cdd:PRK06154 401 ITHDAgsprdqLSPFY-----VASRPGSYLGWGKTTQLGYGLGLAMGAK-----LARPDALVINLWGDAAFGMTGMDFET 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 458 AAQYNVPYVLIMLNN----EYLGLIRQAEIGYGMNyqvdihydEFGTDNVKLMEAYGCSGQRVWEPADISGAIQWArKEA 533
Cdd:PRK06154 471 AVRERIPILTILLNNfsmgGYDKVMPVSTTKYRAT--------DISGDYAAIARALGGYGERVEDPEMLVPALLRA-LRK 541
|
570
....*....|....*.
gi 1941825792 534 VATSRPVLVEIMIERE 549
Cdd:PRK06154 542 VKEGTPALLEVITSEE 557
|
|
| acolac_catab |
TIGR02418 |
acetolactate synthase, catabolic; Acetolactate synthase (EC 2.2.1.6) combines two molecules of ... |
8-551 |
9.78e-67 |
|
acetolactate synthase, catabolic; Acetolactate synthase (EC 2.2.1.6) combines two molecules of pyruvate to yield 2-acetolactate with the release of CO2. This reaction may be involved in either valine biosynthesis (biosynthetic) or conversion of pyruvate to acetoin and possibly to 2,3-butanediol (catabolic). The biosynthetic type, described by TIGR00118, is also capable of forming acetohydroxybutyrate from pyruvate and 2-oxobutyrate for isoleucine biosynthesis. The family described here, part of the same larger family of thiamine pyrophosphate-dependent enzymes (pfam00205, pfam02776) is the catabolic form, generally found associated with in species with acetolactate decarboxylase and usually found in the same operon. The model may not encompass all catabolic acetolactate synthases, but rather one particular clade in the larger TPP-dependent enzyme family. [Energy metabolism, Fermentation]
Pssm-ID: 131471 [Multi-domain] Cd Length: 539 Bit Score: 226.17 E-value: 9.78e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 8 VSIMVDEGVDIAFGCPGAAILPLYKAMEEDGrIDHLTVRHEEGATHMADGWARTNGKVGVAIATSGPGATNLVTGLYTAQ 87
Cdd:TIGR02418 6 VDQLENQGVRYVFGIPGAKIDRVFDALEDKG-IELIVVRHEQNAAFMAQAVGRITGKPGVALVTSGPGCSNLVTGLATAN 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 88 ADSIPMVCLTGQAVSPKLHQEAFQAVDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAGRPGPVLIDLPLDLAkrei 167
Cdd:TIGR02418 85 SEGDPVVAIGGQVKRADLLKLTHQSMDNVALFRPITKYSAEVQDPDALSEVVANAFRAAESGKPGAAFVSLPQDVV---- 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 168 tyDAEIDTRLPVPAVEPHL-PRVERALDMLLA----AERPLILAGGGVILADAGSELRELVEELRVPFQVTLMGKGVIED 242
Cdd:TIGR02418 161 --DSPVSVKAIPASYAPKLgAAPDDAIDEVAEaiqnAKLPVLLLGLRASSPETTEAVRRLLKKTQLPVVETFQGAGAVSR 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 243 DHELNL-GTTGIQTSQryANASFL-ESDFVLAVG-------ARFGDRHTGANIdiyrgertfVHVDIEPAQIGKVFEPDL 313
Cdd:TIGR02418 239 ELEDHFfGRVGLFRNQ--PGDRLLkQADLVITIGydpieyePRNWNSENDATI---------VHIDVEPAQIDNNYQPDL 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 314 GIVSDAGLFLTALLAEARKRKARADVGSWVERCQELKRTLVRRE-DFDSTPVKAPRAYKEINEAFDENTYFVTAIGLYQI 392
Cdd:TIGR02418 308 ELVGDIASTLDLLAERIPGYELPPDALAILEDLKQQREALDRVPaTLKQAHLHPLEIIKAMQAIVTDDVTVTVDMGSHYI 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 393 WGGQHQKAYLPRHYQVCGQAGPLGWEVPAAIGVkkaleGMGEPDAEVVGIVGDYGFQYLVEELAVAAQYNVPYVLIMLN- 471
Cdd:TIGR02418 388 WMARYFRSYRARHLLISNGMQTLGVALPWAIGA-----ALVRPNTKVVSVSGDGGFLFSSMELETAVRLKLNIVHIIWNd 462
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 472 NEYLGLIRQAEIGYGMNYQVDihydeFG-TDNVKLMEAYGCSGQRVWEPADISGAIqwarKEAVATSRPVLVEIMIEREA 550
Cdd:TIGR02418 463 NGYNMVEFQEEMKYQRSSGVD-----FGpIDFVKYAESFGAKGLRVESPDQLEPTL----RQAMEVEGPVVVDIPVDYSD 533
|
.
gi 1941825792 551 N 551
Cdd:TIGR02418 534 N 534
|
|
| TPP_Gcl |
cd02006 |
Thiamine pyrophosphate (TPP) family, Gcl subfamily, TPP-binding module; composed of proteins ... |
359-555 |
1.12e-66 |
|
Thiamine pyrophosphate (TPP) family, Gcl subfamily, TPP-binding module; composed of proteins similar to Escherichia coli glyoxylate carboligase (Gcl). E. coli glyoxylate carboligase, plays a key role in glyoxylate metabolism where it catalyzes the condensation of two molecules of glyoxylate to give tartronic semialdehyde and carbon dioxide. This enzyme requires TPP, magnesium ion and FAD as cofactors.
Pssm-ID: 238964 [Multi-domain] Cd Length: 202 Bit Score: 215.22 E-value: 1.12e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 359 FDSTPVKAPRAYKEINEAFDENTYFVTAIGLYQIWGGQHQKAYLPRHYQVCGQAGPLGWEVPAAIGVKKAlegmgEPDAE 438
Cdd:cd02006 3 FDDVPIKPQRVYEEMNKAFGRDVRYVTTIGLSQIAGAQMLHVYKPRHWINCGQAGPLGWTVPAALGVAAA-----DPDRQ 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 439 VVGIVGDYGFQYLVEELAVAAQYNVPYVLIMLNNEYLGLIRQAEIGYGMNYQVDIHYDE--------FGTDNVKLMEAYG 510
Cdd:cd02006 78 VVALSGDYDFQFMIEELAVGAQHRIPYIHVLVNNAYLGLIRQAQRAFDMDYQVNLAFENinsselggYGVDHVKVAEGLG 157
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 1941825792 511 CSGQRVWEPADISGAIQWARKEAVATSRPVLVEIMIEREANTPHG 555
Cdd:cd02006 158 CKAIRVTKPEELAAAFEQAKKLMAEHRVPVVVEAILERVTNISMG 202
|
|
| PRK06457 |
PRK06457 |
pyruvate dehydrogenase; Provisional |
1-547 |
3.73e-64 |
|
pyruvate dehydrogenase; Provisional
Pssm-ID: 180570 [Multi-domain] Cd Length: 549 Bit Score: 219.32 E-value: 3.73e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 1 MPAM-NAAVSIMVDEGVDIAFGCPGAAILPLYKAMEEDgRIDHLTVRHEEGATHMADGWARTNGKVGVAIATSGPGATNL 79
Cdd:PRK06457 1 MPSVaEVIIRVLEDNGIQRIYGIPGDSIDPLVDAIRKS-KVKYVQVRHEEGAALAASVEAKITGKPSACMGTSGPGSIHL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 80 VTGLYTAQADSIPMVCLTGQAVSPKLHQEAFQAVDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAGRpGPVLIDLP 159
Cdd:PRK06457 80 LNGLYDAKMDHAPVIALTGQVESDMIGHDYFQEVNLTKLFDDVAVFNQILINPENAEYIIRRAIREAISKR-GVAHINLP 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 160 LDLAKREITYDAEIDTRLPVPAVEPHLPRVERALDmllAAERPLILAGGGVIlaDAGSELRELVEELRVPFQVTLMGKGV 239
Cdd:PRK06457 159 VDILRKSSEYKGSKNTEVGKVKYSIDFSRAKELIK---ESEKPVLLIGGGTR--GLGKEINRFAEKIGAPIIYTLNGKGI 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 240 IEDDHELNLGTTGIQTSQRYANAsFLESDFVLAVGARFgdrhtgANIDIYRGERTFVHVDIEPAQIGKVFEPDLGIVSDA 319
Cdd:PRK06457 234 LPDLDPKVMGGIGLLGTKPSIEA-MDKADLLIMLGTSF------PYVNFLNKSAKVIQVDIDNSNIGKRLDVDLSYPIPV 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 320 GLFLTALLAEARKR---KARADVGSWVERcqelkrtLVRREDFDSTPVKAPRAYKEINEAFDENTYFVTAIGLYQIWGGQ 396
Cdd:PRK06457 307 AEFLNIDIEEKSDKfyeELKGKKEDWLDS-------ISKQENSLDKPMKPQRVAYIVSQKCKKDAVIVTDTGNVTMWTAR 379
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 397 HQKAYLPRHYQVCGQAGPLGWEVPAAIGVKKAlegmGEPDAEVVGIVGDYGFQYLVEELAVAAQYNVPYVLIMLNNEYLG 476
Cdd:PRK06457 380 HFRASGEQTFIFSAWLGSMGIGVPGSVGASFA----VENKRQVISFVGDGGFTMTMMELITAKKYDLPVKIIIYNNSKLG 455
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1941825792 477 LIR--QAEIGYGmNYQVDIHYDEFGtdnvKLMEAYGCSGQRVWEPADISGAIqwarKEAVATSRPVLVEIMIE 547
Cdd:PRK06457 456 MIKfeQEVMGYP-EWGVDLYNPDFT----KIAESIGFKGFRLEEPKEAEEII----EEFLNTKGPAVLDAIVD 519
|
|
| PRK07064 |
PRK07064 |
thiamine pyrophosphate-binding protein; |
15-544 |
4.52e-62 |
|
thiamine pyrophosphate-binding protein;
Pssm-ID: 180820 [Multi-domain] Cd Length: 544 Bit Score: 213.70 E-value: 4.52e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 15 GVDIAFGCPGAAILPLYKAMEEDGRIDHLTVRHEEGATHMADGWARTNGKVGVAIATSGPGATNLVTGLYTAQADSIPMV 94
Cdd:PRK07064 17 GVKTAFGVISIHNMPILDAIGRRGKIRFVPARGEAGAVNMADAHARVSGGLGVALTSTGTGAGNAAGALVEALTAGTPLL 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 95 CLTGQAVSPKLHQEA---FQAVDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAGRPGPVLIDLPLDLAKREITYDA 171
Cdd:PRK07064 97 HITGQIETPYLDQDLgyiHEAPDQLTMLRAVSKAAFRVRSAETALATIREAVRVALTAPTGPVSVEIPIDIQAAEIELPD 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 172 eiDTR-LPVPAVEPHLPRVERALDMLLAAERPLILAGGGVilADAGSELRELVeELRVPFQVTLMGKGVIEDDHELNLGT 250
Cdd:PRK07064 177 --DLApVHVAVPEPDAAAVAELAERLAAARRPLLWLGGGA--RHAGAEVKRLV-DLGFGVVTSTQGRGVVPEDHPASLGA 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 251 TGIQTSqryANASFLESDFVLAVGARFGDRHTGAnidiYRGE--RTFVHVDIEPAQIGKVFEPDLGIVSDAGLFLTALLA 328
Cdd:PRK07064 252 FNNSAA---VEALYKTCDLLLVVGSRLRGNETLK----YSLAlpRPLIRVDADAAADGRGYPNDLFVHGDAARVLARLAD 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 329 EARKRkARADvGSWVERCQELKRTLVRredfdsTPVKAPRAYKEINE----AFDENTYFVTAIGLY-QIWGGQHQKAYLP 403
Cdd:PRK07064 325 RLEGR-LSVD-PAFAADLRAAREAAVA------DLRKGLGPYAKLVDalraALPRDGNWVRDVTISnSTWGNRLLPIFEP 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 404 RHyQVCGQAGPLGWEVPAAIGVkkaleGMGEPDAEVVGIVGDYGFQYLVEELAVAAQYNVPYVLIMLNNEYLGLIRQAEI 483
Cdd:PRK07064 397 RA-NVHALGGGIGQGLAMAIGA-----ALAGPGRKTVGLVGDGGLMLNLGELATAVQENANMVIVLMNDGGYGVIRNIQD 470
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1941825792 484 GYgmnYQVDIHYDEFGT-DNVKLMEAYGCSGQRVWEPADISGAIQwarkEAVATSRPVLVEI 544
Cdd:PRK07064 471 AQ---YGGRRYYVELHTpDFALLAASLGLPHWRVTSADDFEAVLR----EALAKEGPVLVEV 525
|
|
| TPP_PYR_POX_like |
cd07035 |
Pyrimidine (PYR) binding domain of POX and related proteins; Thiamine pyrophosphate (TPP ... |
6-159 |
1.44e-61 |
|
Pyrimidine (PYR) binding domain of POX and related proteins; Thiamine pyrophosphate (TPP family), pyrimidine (PYR) binding domain of pyruvate oxidase (POX) and related protiens subfamily. The PYR domain is found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. TPP binds in the cleft formed by a PYR domain and a PP domain. The PYR domain, binds the aminopyrimidine ring of TPP, the PP domain binds the diphosphate residue. A polar interaction between the conserved glutamate of the PYR domain and the N1' of the TPP aminopyrimidine ring is shared by most TPP-dependent enzymes, and participates in the activation of TPP. For glyoxylate carboligase, which belongs to this subfamily, but lacks this conserved glutamate, the rate of the initial TPP activation step is reduced but the ensuing steps of the enzymic reaction proceed efficiently. The PYR and PP domains have a common fold, but do not share strong sequence conservation. The PP domain is not included in this sub-family. Most TPP-dependent enzymes have the PYR and PP domains on the same subunit although these domains can be alternatively arranged in the primary structure. TPP-dependent enzymes are multisubunit proteins, the smallest catalytic unit being a dimer-of-active sites, for many the active sites lie between PP and PYR domains on different subunits. POX decarboxylates pyruvate, producing hydrogen peroxide and the energy-storage metabolite acetylphosphate. This subfamily includes pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC catalyzes the conversion of pyruvate to acetaldehyde and CO2 in alcoholic fermentation. IPDC plays a role in the indole-3-pyruvic acid (IPA) pathway in plants and various plant-associated bacteria, it catalyzes the decarboxylation of IPA to IAA. This subfamily also includes the large catalytic subunit of acetohydroxyacid synthase (AHAS). AHAS catalyzes the condensation of two molecules of pyruvate to give the acetohydroxyacid, 2-acetolactate, a precursor of the branched chain amino acids, valine and leucine. AHAS also catalyzes the condensation of pyruvate and 2-ketobutyrate to form 2-aceto-2-hydroxybutyrate in isoleucine biosynthesis. Methanococcus jannaschii sulfopyruvate decarboxylase (MjComDE) and phosphonopyruvate decarboxylase (PpyrDc) also belong to this subfamily. PpyrDc is a homotrimeric enzyme having the PP and PYR domains tandemly arranged on the same subunit. It functions in the biosynthesis of C-P compounds such as bialaphos tripeptide in Streptomyces hygroscopicus. MjComDE is a dodecamer having the PYR and PP domains on different subunits, it has six alpha (PYR/ComD) subunits and six beta (PP/ComE) subunits. MjComDE catalyzes the decarboxylation of sulfopyruvic acid to sulfoacetaldehyde in the coenzyme M pathway.
Pssm-ID: 132918 [Multi-domain] Cd Length: 155 Bit Score: 200.07 E-value: 1.44e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 6 AAVSIMVDEGVDIAFGCPGAAILPLYKAMEEDGrIDHLTVRHEEGATHMADGWARTNGKVGVAIATSGPGATNLVTGLYT 85
Cdd:cd07035 2 ALVEALKAEGVDHVFGVPGGAILPLLDALARSG-IRYILVRHEQGAVGMADGYARATGKPGVVLVTSGPGLTNAVTGLAN 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1941825792 86 AQADSIPMVCLTGQAVSPKLHQEAFQAVDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAGRPGPVLIDLP 159
Cdd:cd07035 81 AYLDSIPLLVITGQRPTAGEGRGAFQEIDQVALFRPITKWAYRVTSPEEIPEALRRAFRIALSGRPGPVALDLP 154
|
|
| PRK05858 |
PRK05858 |
acetolactate synthase; |
7-553 |
5.89e-60 |
|
acetolactate synthase;
Pssm-ID: 235629 [Multi-domain] Cd Length: 542 Bit Score: 208.04 E-value: 5.89e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 7 AVSIMVDEGVDIAFGCPGAAILPLYKAMEEDGrIDHLTVRHEEGATHMADGWARTNGKVGVAIATSGPGATNLVTGLYTA 86
Cdd:PRK05858 11 AARRLKAHGVDTMFTLSGGHLFPLYDGAREEG-IRLIDVRHEQTAAFAAEAWAKLTRVPGVAVLTAGPGVTNGMSAMAAA 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 87 QADSIPMVCLTGQAVSPKLHQEAFQAVDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAGRPGPVLIDLPLDLAkre 166
Cdd:PRK05858 90 QFNQSPLVVLGGRAPALRWGMGSLQEIDHVPFVAPVTKFAATAQSAENAGRLVDQALQAAVTPHRGPVFVDFPMDHA--- 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 167 itYDAEIDTRLPVPAVEPHL-----PR-VERALDMLLAAERPLILAGGGVILADAGSELRELVEELRVPFQVTLMGKGVI 240
Cdd:PRK05858 167 --FSMADDDGRPGALTELPAgptpdPDaLARAAGLLAEAQRPVIMAGTDVWWGHAEAALLRLAEELGIPVLMNGMGRGVV 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 241 EDDHELNLgttgiqtsQRYANASFLESDFVLAVGARFGDRhtgANIDIYRGERTFVHVDIEPAQIGKVFEPDLGIVSDAG 320
Cdd:PRK05858 245 PADHPLAF--------SRARGKALGEADVVLVVGVPMDFR---LGFGVFGGTAQLVHVDDAPPQRAHHRPVAAGLYGDLS 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 321 LFLTALLAEARKRKARADvgsWVERCQELKRTLVRRE----DFDSTPVKAPRAYKEINEAFDENTYFVTAIGLYQIWGGQ 396
Cdd:PRK05858 314 AILSALAGAGGDRTDHQG---WIEELRTAETAARARDaaelADDRDPIHPMRVYGELAPLLDRDAIVIGDGGDFVSYAGR 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 397 HQKAYLPRHYQVCGQAGPLGWEVPAAIGVKKAlegmgEPDAEVVGIVGDYGFQYLVEELAVAAQYNVPYVLIMLNNEYLG 476
Cdd:PRK05858 391 YIDPYRPGCWLDPGPFGCLGTGPGYALAARLA-----RPSRQVVLLQGDGAFGFSLMDVDTLVRHNLPVVSVIGNNGIWG 465
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 477 LIR---QAEIGYGM--NYQVDIHYDEfgtdnvkLMEAYGCSGQRVWEPADISGAIQwarkEAVATSRPVLVEIMIEREAN 551
Cdd:PRK05858 466 LEKhpmEALYGYDVaaDLRPGTRYDE-------VVRALGGHGELVTVPAELGPALE----RAFASGVPYLVNVLTDPSVA 534
|
..
gi 1941825792 552 TP 553
Cdd:PRK05858 535 YP 536
|
|
| TPP_enzyme_N |
pfam02776 |
Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; |
8-168 |
2.51e-57 |
|
Thiamine pyrophosphate enzyme, N-terminal TPP binding domain;
Pssm-ID: 460690 [Multi-domain] Cd Length: 169 Bit Score: 189.37 E-value: 2.51e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 8 VSIMVDEGVDIAFGCPGAAILPLYKAMEEDGRIDHLTVRHEEGATHMADGWARTNGKVGVAIATSGPGATNLVTGLYTAQ 87
Cdd:pfam02776 6 ADVLKALGVDTVFGVPGGHILPLLDALAKSPGIRYVLTRHEQGAAFAADGYARATGKPGVVLVTSGPGATNALTGLANAY 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 88 ADSIPMVCLTGQAVSPKLHQEAFQA-VDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAGRPGPVLIDLPLDLAKRE 166
Cdd:pfam02776 86 VDSVPLLVISGQRPRSLVGRGALQQeLDQLALFRPVTKWAVRVTSADEIPEVLRRAFRAALSGRPGPVYLEIPLDVLLEE 165
|
..
gi 1941825792 167 IT 168
Cdd:pfam02776 166 VD 167
|
|
| PRK09259 |
PRK09259 |
putative oxalyl-CoA decarboxylase; Validated |
15-555 |
2.60e-52 |
|
putative oxalyl-CoA decarboxylase; Validated
Pssm-ID: 236433 [Multi-domain] Cd Length: 569 Bit Score: 187.89 E-value: 2.60e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 15 GVDIAFGCPGAAILPLYKAMEEDGrIDHLTVRHEEGATHMADGWARTNGKVGVAIATSGPGATNLVTGLYTAQADSIPMV 94
Cdd:PRK09259 24 GIDTIYGVVGIPITDLARLAQAEG-IRYIGFRHEQSAGNAAAAAGFLTQKPGVCLTVSAPGFLNGLTALANATTNCFPMI 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 95 CLTGQAVSP--KLHQEAFQAVDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAGRPGPVLIDLPLDLAKReiTYDAE 172
Cdd:PRK09259 103 MISGSSEREivDLQQGDYEELDQLNAAKPFCKAAFRVNRAEDIGIGVARAIRTAVSGRPGGVYLDLPAKVLAQ--TMDAD 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 173 ---------IDtrlPVPAVEPHLPRVERALDMLLAAERPLILAGGGVILADAGSELRELVEELRVPFQVTLMGKGVIEDD 243
Cdd:PRK09259 181 ealtslvkvVD---PAPAQLPAPEAVDRALDLLKKAKRPLIILGKGAAYAQADEQIREFVEKTGIPFLPMSMAKGLLPDT 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 244 HELNLGttgiqtsqryANASFL--ESDFVLAVGAR------FGDRHTganidiYRGERTFVHVDIEPAQIGKVFEPDLGI 315
Cdd:PRK09259 258 HPQSAA----------AARSLAlaNADVVLLVGARlnwllsHGKGKT------WGADKKFIQIDIEPQEIDSNRPIAAPV 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 316 VSDAGLFLTALLAEARKRKARADVgSWVERCQELKRT----LVRREDFDSTPVKAPRAYKEINEAFDEN--TYFVT---- 385
Cdd:PRK09259 322 VGDIGSVMQALLAGLKQNTFKAPA-EWLDALAERKEKnaakMAEKLSTDTQPMNFYNALGAIRDVLKENpdIYLVNegan 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 386 -------AIGLYQiwggqhqkaylPRHYQVCGQAGPLGWEVPAAIGVkkALEGmGEPdaeVVGIVGDYGFQYLVEELAVA 458
Cdd:PRK09259 401 tldlarnIIDMYK-----------PRHRLDCGTWGVMGIGMGYAIAA--AVET-GKP---VVAIEGDSAFGFSGMEVETI 463
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 459 AQYNVPYVLIMLNNEylGLIRQAEIGYGMNYQV-------DIHYDefgtdnvKLMEAYGCSGQRVWEPADISGAIqwarK 531
Cdd:PRK09259 464 CRYNLPVTVVIFNNG--GIYRGDDVNLSGAGDPsptvlvhHARYD-------KMMEAFGGVGYNVTTPDELRHAL----T 530
|
570 580
....*....|....*....|....
gi 1941825792 532 EAVATSRPVLVEIMIEREANTPHG 555
Cdd:PRK09259 531 EAIASGKPTLINVVIDPAAGTESG 554
|
|
| TPP_enzyme_M |
pfam00205 |
Thiamine pyrophosphate enzyme, central domain; The central domain of TPP enzymes contains a ... |
189-326 |
7.48e-48 |
|
Thiamine pyrophosphate enzyme, central domain; The central domain of TPP enzymes contains a 2-fold Rossman fold.
Pssm-ID: 425523 [Multi-domain] Cd Length: 137 Bit Score: 163.12 E-value: 7.48e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 189 VERALDMLLAAERPLILAGGGVILADAGSELRELVEELRVPFQVTLMGKGVIEDDHELNLGTTGIqTSQRYANASFLESD 268
Cdd:pfam00205 1 IEKAAELLKKAKRPVILAGGGVRRSGASEELRELAEKLGIPVVTTLMGKGAFPEDHPLYLGMLGM-HGTPAANEALEEAD 79
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 1941825792 269 FVLAVGARFGDRHTGANIDIYRGERTFVHVDIEPAQIGKVFEPDLGIVSDAGLFLTAL 326
Cdd:pfam00205 80 LVLAVGARFDDIRTTGKLPEFAPDAKIIHIDIDPAEIGKNYPVDVPIVGDAKETLEAL 137
|
|
| PDC1 |
COG3961 |
TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase [Carbohydrate ... |
13-548 |
3.61e-46 |
|
TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase [Carbohydrate transport and metabolism, Coenzyme transport and metabolism, General function prediction only]; TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase is part of the Pathway/BioSystem: Pyruvate oxidation
Pssm-ID: 443161 [Multi-domain] Cd Length: 545 Bit Score: 170.34 E-value: 3.61e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 13 DEGVDIAFGCPGAAILPLYKAMEEDGRIDHLTVRHEEGATHMADGWARTNGkVGVAIATSGPGATNLVTGLYTAQADSIP 92
Cdd:COG3961 17 ELGIRHIFGVPGDYNLPFLDAIEAHPGIRWVGCCNELNAGYAADGYARVNG-LGALVTTYGVGELSAINGIAGAYAERVP 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 93 MVCLTG------QAVSPKLH-------QEAFQavdivEIAKPVTKWAVQIKE---PAQIPWAFREAFRIARagrpgPVLI 156
Cdd:COG3961 96 VVHIVGapgtraQRRGPLLHhtlgdgdFDHFL-----RMFEEVTVAQAVLTPenaAAEIDRVLAAALREKR-----PVYI 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 157 DLPLDLAKREITYDAEiDTRLPVPAVEPHLPR--VERALDMLLAAERPLILAGGGVILADAGSELRELVEELRVPFQVTL 234
Cdd:COG3961 166 ELPRDVADAPIEPPEA-PLPLPPPASDPAALAaaVAAAAERLAKAKRPVILAGVEVHRFGLQEELLALAEKTGIPVATTL 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 235 MGKGVIEDDHELNLGTTGIQTSQRYANASFLESDFVLAVGARFGDRHTG---ANIDiyrGERTfvhVDIEP--AQIG-KV 308
Cdd:COG3961 245 LGKSVLDESHPQFIGTYAGAASSPEVREYVENADCVLCLGVVFTDTNTGgftAQLD---PERT---IDIQPdsVRVGgHI 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 309 FEPdlgiVS--DaglFLTALLAEARKRKARADVgswvercqeLKRTLVRREDFDSTPVKAPRAYKEINEAFDENTYFVTA 386
Cdd:COG3961 319 YPG----VSlaD---FLEALAELLKKRSAPLPA---------PAPPPPPPPAAPDAPLTQDRLWQRLQAFLDPGDIVVAD 382
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 387 IG--LYQIWGgqhqkAYLPRHYQVCGQA--GPLGWEVPAAIGVkkaleGMGEPDAEVVGIVGDYGFQYLVEELAVAAQYN 462
Cdd:COG3961 383 TGtsLFGAAD-----LRLPEGATFIAQPlwGSIGYTLPAALGA-----ALAAPDRRVILLVGDGAFQLTAQELSTMLRYG 452
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 463 VPYVLIMLNNEylglirqaeiGYGMnyQVDIHYDEfGTDNV-------KLMEAYGCS---GQRVWEPADISGAIQWARKe 532
Cdd:COG3961 453 LKPIIFVLNND----------GYTI--ERAIHGPD-GPYNDianwdyaKLPEAFGGGnalGFRVTTEGELEEALAAAEA- 518
|
570
....*....|....*.
gi 1941825792 533 avATSRPVLVEIMIER 548
Cdd:COG3961 519 --NTDRLTLIEVVLDK 532
|
|
| PRK08327 |
PRK08327 |
thiamine pyrophosphate-requiring protein; |
13-548 |
7.71e-45 |
|
thiamine pyrophosphate-requiring protein;
Pssm-ID: 236243 [Multi-domain] Cd Length: 569 Bit Score: 167.10 E-value: 7.71e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 13 DEGVDIAFGCPGAAILPLYKAMEEDGRIDH-----LTVRHEEGATHMADGWARTNGKVGVAIATSGPGATNLVTGLYTAQ 87
Cdd:PRK08327 19 ELGVDYIFINSGTDYPPIIEAKARARAAGRplpefVICPHEIVAISMAHGYALVTGKPQAVMVHVDVGTANALGGVHNAA 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 88 ADSIPMVCLTGQavSP------------KLH--QEAFqavDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAGRPGP 153
Cdd:PRK08327 99 RSRIPVLVFAGR--SPyteegelgsrntRIHwtQEMR---DQGGLVREYVKWDYEIRRGDQIGEVVARAIQIAMSEPKGP 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 154 VLIDLPldlakREI----TYDAEIDTRLPVPAVEPHLPR--VERALDMLLAAERPLILAGGGVILADAGSELRELVEELR 227
Cdd:PRK08327 174 VYLTLP-----REVlaeeVPEVKADAGRQMAPAPPAPDPedIARAAEMLAAAERPVIITWRAGRTAEGFASLRRLAEELA 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 228 VP---FQVTLMgkgVIEDDHELNLGTTgiqtsqryANASFLESDFVLAVGAR--FGDRHTGANIDIyrgerTFVHVDIEP 302
Cdd:PRK08327 249 IPvveYAGEVV---NYPSDHPLHLGPD--------PRADLAEADLVLVVDSDvpWIPKKIRPDADA-----RVIQIDVDP 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 303 AQiGKV----FEPDLGIVSDAGLFLTALLAEA---------RKRKARADVGSWVERCQELKRTLVRREDfDSTPVKAPRA 369
Cdd:PRK08327 313 LK-SRIplwgFPCDLCIQADTSTALDQLEERLkslasaerrRARRRRAAVRELRIRQEAAKRAEIERLK-DRGPITPAYL 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 370 YKEINEAFDENTYFVTAIGLYQiwggQHQKAYLPRHYQVCGQAGPLGWEVPAAIGVKkalegMGEPDAEVVGIVGDYGFQ 449
Cdd:PRK08327 391 SYCLGEVADEYDAIVTEYPFVP----RQARLNKPGSYFGDGSAGGLGWALGAALGAK-----LATPDRLVIATVGDGSFI 461
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 450 YLVEE--LAVAAQYNVPYVLIMLNNEYLGLIRQAEI-----GYG--MNYQVDIHYDEfGTDNVKLMEAYGCSGQRVWEPA 520
Cdd:PRK08327 462 FGVPEaaHWVAERYGLPVLVVVFNNGGWLAVKEAVLevypeGYAarKGTFPGTDFDP-RPDFAKIAEAFGGYGERVEDPE 540
|
570 580
....*....|....*....|....*...
gi 1941825792 521 DISGAIQWARKEAVATSRPVLVEIMIER 548
Cdd:PRK08327 541 ELKGALRRALAAVRKGRRSAVLDVIVDR 568
|
|
| PRK09124 |
PRK09124 |
ubiquinone-dependent pyruvate dehydrogenase; |
15-549 |
1.17e-40 |
|
ubiquinone-dependent pyruvate dehydrogenase;
Pssm-ID: 181661 [Multi-domain] Cd Length: 574 Bit Score: 155.15 E-value: 1.17e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 15 GVDIAFGCPGAAILPLYKAMEEDGRIDHLTVRHEEGATHMADGWARTNGKVGVAIATSGPGATNLVTGLYTAQADSIPMV 94
Cdd:PRK09124 17 GVKRIWGVTGDSLNGLSDSLRRMGTIEWMHTRHEEVAAFAAGAEAQLTGELAVCAGSCGPGNLHLINGLFDCHRNHVPVL 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 95 CLTGQAVSPKLHQEAFQAVDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRIArAGRPGPVLIDLPLDLAKREITYDAEID 174
Cdd:PRK09124 97 AIAAHIPSSEIGSGYFQETHPQELFRECSHYCELVSNPEQLPRVLAIAMRKA-ILNRGVAVVVLPGDVALKPAPERATPH 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 175 -TRLPVPAVEPHLPRVERALDMLLAAERPLILAGGGVilADAGSELRELVEELRVPFQVTLMGKGVIEDDHELNLGTTG- 252
Cdd:PRK09124 176 wYHAPQPVVTPAEEELRKLAALLNGSSNITLLCGSGC--AGAHDELVALAETLKAPIVHALRGKEHVEYDNPYDVGMTGl 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 253 IQTSQRYanASFLESDFVLAVGARFGDRhtganiDIYRGERTFVHVDIEPAQIGKVFEPDLGIVSDAGLFLTALLAEARK 332
Cdd:PRK09124 254 IGFSSGY--HAMMNCDTLLMLGTDFPYR------QFYPTDAKIIQIDINPGSLGRRSPVDLGLVGDVKATLAALLPLLEE 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 333 RKARAdvgsWVERCqeLKRTLVRREDFDS--------TPVKAPRAYKEINEAFDENTYFVTAIGLYQIWGGQHQKAYLPR 404
Cdd:PRK09124 326 KTDRK----FLDKA--LEHYRKARKGLDDlavpsdggKPIHPQYLARQISEFAADDAIFTCDVGTPTVWAARYLKMNGKR 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 405 HYQVCGQAGPLGWEVPAAIGVKKAlegmgEPDAEVVGIVGDYGFQYLVEELAVAAQYNVPYVLIMLNNEYLGLIrQAEI- 483
Cdd:PRK09124 400 RLLGSFNHGSMANAMPQALGAQAA-----HPGRQVVALSGDGGFSMLMGDFLSLVQLKLPVKIVVFNNSVLGFV-AMEMk 473
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1941825792 484 --GYgMNYQVDIHydefGTDNVKLMEAYGCSGQRVWEPADISGAIQwarkEAVATSRPVLVEIMIERE 549
Cdd:PRK09124 474 agGY-LTDGTDLH----NPDFAAIAEACGITGIRVEKASELDGALQ----RAFAHDGPALVDVVTAKQ 532
|
|
| PRK08273 |
PRK08273 |
thiamine pyrophosphate protein; Provisional |
15-543 |
2.50e-40 |
|
thiamine pyrophosphate protein; Provisional
Pssm-ID: 181344 [Multi-domain] Cd Length: 597 Bit Score: 154.68 E-value: 2.50e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 15 GVDIAFGCPGAAILPLYKAMEE-DGRIDHLTVRHEEGATHMADGWARTNGKVGVAIATSGPGATNLVTGLYTAQADSIPM 93
Cdd:PRK08273 17 GVRRVFGYPGDGINGLLGALGRaDDKPEFVQARHEEMAAFMAVAHAKFTGEVGVCLATSGPGAIHLLNGLYDAKLDHVPV 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 94 VCLTGQAVSPKLHQEAFQAVDIVEIAKPV-TKWAVQIKEPAQIPWAFREAFRIARAGRpGPVLIDLPLDLakREITYDA- 171
Cdd:PRK08273 97 VAIVGQQARAALGGHYQQEVDLQSLFKDVaGAFVQMVTVPEQLRHLVDRAVRTALAER-TVTAVILPNDV--QELEYEPp 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 172 -----EIDTRL--PVPAVEPHLPRVERALDMLLAAERPLILAGGGVilADAGSELRELVEELRVPFQVTLMGKGVIEDDH 244
Cdd:PRK08273 174 phahgTVHSGVgyTRPRVVPYDEDLRRAAEVLNAGRKVAILVGAGA--LGATDEVIAVAERLGAGVAKALLGKAALPDDL 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 245 ELNLGTTGIQTSqRYANASFLESDFVLAVGARF---------GDRhtganidiyRGertfVHVDIEPAQIGKVFEPDLGI 315
Cdd:PRK08273 252 PWVTGSIGLLGT-KPSYELMRECDTLLMVGSSFpyseflpkeGQA---------RG----VQIDIDGRMLGLRYPMEVNL 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 316 VSDAGLFLTALLA--EARKRKA-RADVGSWVERCQElkrTLVRREDFDSTPVKAPRAYKEINEAFDENTyFVTA-IGLYQ 391
Cdd:PRK08273 318 VGDAAETLRALLPllERKKDRSwRERIEKWVARWWE---TLEARAMVPADPVNPQRVFWELSPRLPDNA-ILTAdSGSCA 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 392 IWGGQHQKayLPRHYQ--VCGQAGPLGWEVPAAIGVKKAlegmgEPDAEVVGIVGDYGFQYL-VEELAVAAQY-----NV 463
Cdd:PRK08273 394 NWYARDLR--MRRGMMasLSGTLATMGPAVPYAIAAKFA-----HPDRPVIALVGDGAMQMNgMAELITVAKYwrqwsDP 466
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 464 PYVLIMLNNEYLGLI--RQAEIGYGMNYQV-----DIHYDEFGtdnvklmEAYGCSGQRVWEPADISGAiqWArkEAVAT 536
Cdd:PRK08273 467 RLIVLVLNNRDLNQVtwEQRVMEGDPKFEAsqdlpDVPYARFA-------ELLGLKGIRVDDPEQLGAA--WD--EALAA 535
|
....*..
gi 1941825792 537 SRPVLVE 543
Cdd:PRK08273 536 DRPVVLE 542
|
|
| TPP_enzyme_C |
pfam02775 |
Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; |
386-544 |
4.70e-40 |
|
Thiamine pyrophosphate enzyme, C-terminal TPP binding domain;
Pssm-ID: 460689 [Multi-domain] Cd Length: 151 Bit Score: 142.72 E-value: 4.70e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 386 AIGLYQIWGGQHQKAYLPRHYQVCGQAGPLGWEVPAAIGVKkalegMGEPDAEVVGIVGDYGFQYLVEELAVAAQYNVPY 465
Cdd:pfam02775 1 DIGCHQMWAAQYYRFRPPRRYLTSGGLGTMGYGLPAAIGAK-----LARPDRPVVAIAGDGGFQMNLQELATAVRYNLPI 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 466 VLIMLNNEYLGLIR-QAEIGYGMNYQVDIHYDEFGTDNVKLMEAYGCSGQRVWEPADISGAIqwarKEAVATSRPVLVEI 544
Cdd:pfam02775 76 TVVVLNNGGYGMTRgQQTPFGGGRYSGPSGKILPPVDFAKLAEAYGAKGARVESPEELEEAL----KEALEHDGPALIDV 151
|
|
| PRK07092 |
PRK07092 |
benzoylformate decarboxylase; Reviewed |
15-547 |
3.99e-39 |
|
benzoylformate decarboxylase; Reviewed
Pssm-ID: 235931 [Multi-domain] Cd Length: 530 Bit Score: 150.11 E-value: 3.99e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 15 GVDIAFGCPGAAILPLYKAMEEDgrIDHLTVRHEEGATHMADGWARTNGKVGVAIATSGPGATNLVTGLYTAQADSIPMV 94
Cdd:PRK07092 26 GITTVFGNPGSTELPFLRDFPDD--FRYVLGLQEAVVVGMADGYAQATGNAAFVNLHSAAGVGNAMGNLFTAFKNHTPLV 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 95 CLTGQAVSPKLHQEAF-QAVDIVEIAKPVTKWAVqikEPAQ---IPWAFREAFRIARAGRPGPVLIDLPLD--------L 162
Cdd:PRK07092 104 ITAGQQARSILPFEPFlAAVQAAELPKPYVKWSI---EPARaedVPAAIARAYHIAMQPPRGPVFVSIPYDdwdqpaepL 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 163 AKREITYDAeidtrLPVPAVephlprVERALDMLLAAERPLILAGGGVILADAGSELRELVEELRVPFQVTLM-GKGVIE 241
Cdd:PRK07092 181 PARTVSSAV-----RPDPAA------LARLGDALDAARRPALVVGPAVDRAGAWDDAVRLAERHRAPVWVAPMsGRCSFP 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 242 DDHELnlgTTGIQTSQRYANASFLES-DFVLAVGA---RFGDRHTGANIDiyrGERTFVHVdIEPAQIGKVFEPDLGIVS 317
Cdd:PRK07092 250 EDHPL---FAGFLPASREKISALLDGhDLVLVIGApvfTYHVEGPGPHLP---EGAELVQL-TDDPGEAAWAPMGDAIVG 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 318 DAGLFLTALLAEARKRKaradvgswveRCQELKRTLVRREDFDSTPVKAPRAYKEINEAFDENTYFV----TAIGLYQiw 393
Cdd:PRK07092 323 DIRLALRDLLALLPPSA----------RPAPPARPMPPPAPAPGEPLSVAFVLQTLAALRPADAIVVeeapSTRPAMQ-- 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 394 ggqhqkAYLP-RH----YQVCgqAGPLGWEVPAAIGVKkalegMGEPDAEVVGIVGDYGFQYLVEELAVAAQYNVPYVLI 468
Cdd:PRK07092 391 ------EHLPmRRqgsfYTMA--SGGLGYGLPAAVGVA-----LAQPGRRVIGLIGDGSAMYSIQALWSAAQLKLPVTFV 457
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1941825792 469 MLNNEYLGLIRqaEIGYGMNYQVDIHYDEFGTDNVKLMEAYGCSGQRVWEPADISGAIqwarKEAVATSRPVLVEIMIE 547
Cdd:PRK07092 458 ILNNGRYGALR--WFAPVFGVRDVPGLDLPGLDFVALARGYGCEAVRVSDAAELADAL----ARALAADGPVLVEVEVA 530
|
|
| PRK06546 |
PRK06546 |
pyruvate dehydrogenase; Provisional |
3-544 |
4.61e-38 |
|
pyruvate dehydrogenase; Provisional
Pssm-ID: 180614 [Multi-domain] Cd Length: 578 Bit Score: 147.83 E-value: 4.61e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 3 AMNAA---VSIMVDEGVDIAFGCPGAAILPLYKAMEEDGRIDHLTVRHEEGATHMADGWARTNGKVGVAIATSGPGATNL 79
Cdd:PRK06546 2 AKTVAeqlVEQLVAAGVKRIYGIVGDSLNPIVDAVRRTGGIEWVHVRHEEAAAFAAAAEAQLTGKLAVCAGSCGPGNLHL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 80 VTGLYTAQADSIPMVCLTGQAVSPKLHQEAFQAVDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRIArAGRPGPVLIDLP 159
Cdd:PRK06546 82 INGLYDAHRSGAPVLAIASHIPSAQIGSGFFQETHPDRLFVECSGYCEMVSSAEQAPRVLHSAIQHA-VAGGGVSVVTLP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 160 LDLAKREI-TYDAEIDTRLPVPAVEPHLPRVERALDMLLAAERPLILAGGGVilADAGSELRELVEELRVPFQVTLMGKG 238
Cdd:PRK06546 161 GDIADEPApEGFAPSVISPRRPTVVPDPAEVRALADAINEAKKVTLFAGAGV--RGAHAEVLALAEKIKAPVGHSLRGKE 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 239 VIEDDHELNLGTTGIQTsqrY--ANASFLESDFVLAVGARFgdrhtgaNIDIYRGERTFVHVDIEPAQIGKVFEPDLGIV 316
Cdd:PRK06546 239 WIQYDNPFDVGMSGLLG---YgaAHEAMHEADLLILLGTDF-------PYDQFLPDVRTAQVDIDPEHLGRRTRVDLAVH 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 317 SDAGLFLTALLAEARKRKARADVGSWVERCQELKRTLVR---REDFDSTPVKAPRAYKEINEAFDENTYFVTAIGLYQIW 393
Cdd:PRK06546 309 GDVAETIRALLPLVKEKTDRRFLDRMLKKHARKLEKVVGaytRKVEKHTPIHPEYVASILDELAADDAVFTVDTGMCNVW 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 394 GGQHQKAYLPRhyQVCGQA--GPLGWEVPAAIGVKKAlegmgEPDAEVVGIVGDYGFQYLVEELAVAAQYNVPYVLIMLN 471
Cdd:PRK06546 389 AARYITPNGRR--RVIGSFrhGSMANALPHAIGAQLA-----DPGRQVISMSGDGGLSMLLGELLTVKLYDLPVKVVVFN 461
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1941825792 472 NEYLGLIRQAEIGYGMnyqvdihyDEFGTDN-----VKLMEAYGCSGQRVWEPADISGAIqwarKEAVATSRPVLVEI 544
Cdd:PRK06546 462 NSTLGMVKLEMLVDGL--------PDFGTDHppvdyAAIAAALGIHAVRVEDPKDVRGAL----REAFAHPGPALVDV 527
|
|
| TPP_PYR_POX |
cd07039 |
Pyrimidine (PYR) binding domain of POX; Thiamine pyrophosphate (TPP family), pyrimidine (PYR) ... |
8-166 |
8.14e-38 |
|
Pyrimidine (PYR) binding domain of POX; Thiamine pyrophosphate (TPP family), pyrimidine (PYR) binding domain of pyruvate oxidase (POX) subfamily. The PYR domain is found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. TPP binds in the cleft formed by a PYR domain and a PP domain. The PYR domain, binds the aminopyrimidine ring of TPP, the PP domain binds the diphosphate residue. The PYR and PP domains have a common fold, but do not share strong sequence conservation. The PP domain is not included in this sub-family. Most TPP-dependent enzymes have the PYR and PP domains on the same subunit although these domains can be alternatively arranged in the primary structure. TPP-dependent enzymes are multisubunit proteins, the smallest catalytic unit being a dimer-of-active sites. Lactobacillus plantarum POX is a homotetramer (dimer-of-homodimers), having two active sites per homodimer lying between PYR and PP domains of different subunits. POX decarboxylates pyruvate, producing hydrogen peroxide and the energy-storage metabolite acetylphosphate.
Pssm-ID: 132922 [Multi-domain] Cd Length: 164 Bit Score: 136.91 E-value: 8.14e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 8 VSIMVDEGVDIAFGCPGAAILPLYKAMEEDGRIDHLTVRHEEGATHMADGWARTNGKVGVAIATSGPGATNLVTGLYTAQ 87
Cdd:cd07039 7 VETLENWGVKRVYGIPGDSINGLMDALRREGKIEFIQVRHEEAAAFAASAEAKLTGKLGVCLGSSGPGAIHLLNGLYDAK 86
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1941825792 88 ADSIPMVCLTGQAVSPKLHQEAFQAVDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAGRpGPVLIDLPLDLAKRE 166
Cdd:cd07039 87 RDRAPVLAIAGQVPTDELGTDYFQEVDLLALFKDVAVYNETVTSPEQLPELLDRAIRTAIAKR-GVAVLILPGDVQDAP 164
|
|
| TPP_AHAS |
cd02015 |
Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding ... |
364-551 |
1.21e-37 |
|
Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the acetohydroxyacid, 2-acetolactate. 2-Acetolactate is the precursor of the branched chain amino acids, valine and leucine. AHAS also catalyzes the condensation of pyruvate and 2-ketobutyrate to form 2-aceto-2-hydroxybutyrate in isoleucine biosynthesis. In addition to requiring TPP and a divalent metal ion as cofactors, AHAS requires FAD.
Pssm-ID: 238973 [Multi-domain] Cd Length: 186 Bit Score: 137.24 E-value: 1.21e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 364 VKAPRAYKEINEAFDENTYFVTAIGLYQIWGGQHQKAYLPRHYQVCGQAGPLGWEVPAAIGVKkalegMGEPDAEVVGIV 443
Cdd:cd02015 1 IKPQEVIKELSELTPGDAIVTTDVGQHQMWAAQYYRFKKPRSWLTSGGLGTMGFGLPAAIGAK-----VARPDKTVICID 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 444 GDYGFQYLVEELAVAAQYNVPYVLIMLNNEYLGLIRQ-AEIGYGMNYqvdIHYDEFG-TDNVKLMEAYGCSGQRVWEPAD 521
Cdd:cd02015 76 GDGSFQMNIQELATAAQYNLPVKIVILNNGSLGMVRQwQELFYEGRY---SHTTLDSnPDFVKLAEAYGIKGLRVEKPEE 152
|
170 180 190
....*....|....*....|....*....|
gi 1941825792 522 ISGAIqwarKEAVATSRPVLVEIMIEREAN 551
Cdd:cd02015 153 LEAAL----KEALASDGPVLLDVLVDPEEN 178
|
|
| TPP_enzymes |
cd00568 |
Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic ... |
368-546 |
6.40e-33 |
|
Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and the branched chain alpha-keto acid dehydrogenase complexes.
Pssm-ID: 238318 [Multi-domain] Cd Length: 168 Bit Score: 123.90 E-value: 6.40e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 368 RAYKEINEAFDENTYFVTAIGLYQIWGGQHQKAYLPRHYQVCGQAGPLGWEVPAAIGVKkalegMGEPDAEVVGIVGDYG 447
Cdd:cd00568 1 RVLAALRAALPEDAIVVNDAGNSAYWAYRYLPLRRGRRFLTSTGFGAMGYGLPAAIGAA-----LAAPDRPVVCIAGDGG 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 448 FQYLVEELAVAAQYNVPYVLIMLNNEYLGLIRQaeiGYGMNYQVDIHYDEFGT-DNVKLMEAYGCSGQRVWEPADISGAI 526
Cdd:cd00568 76 FMMTGQELATAVRYGLPVIVVVFNNGGYGTIRM---HQEAFYGGRVSGTDLSNpDFAALAEAYGAKGVRVEDPEDLEAAL 152
|
170 180
....*....|....*....|
gi 1941825792 527 qwarKEAVATSRPVLVEIMI 546
Cdd:cd00568 153 ----AEALAAGGPALIEVKT 168
|
|
| TPP_enzyme_PYR |
cd06586 |
Pyrimidine (PYR) binding domain of thiamine pyrophosphate (TPP)-dependent enzymes; Thiamine ... |
6-159 |
2.51e-25 |
|
Pyrimidine (PYR) binding domain of thiamine pyrophosphate (TPP)-dependent enzymes; Thiamine pyrophosphate (TPP) family, pyrimidine (PYR) binding domain; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. TPP binds in the cleft formed by a PYR domain and a PP domain. The PYR domain, binds the aminopyrimidine ring of TPP, the PP domain binds the diphosphate residue. A polar interaction between the conserved glutamate of the PYR domain and the N1' of the TPP aminopyrimidine ring is shared by most TPP-dependent enzymes, and participates in the activation of TPP. The PYR and PP domains have a common fold, but do not share strong sequence conservation. The PP domain is not included in this group. Most TPP-dependent enzymes have the PYR and PP domains on the same subunit although these domains can be alternatively arranged in the primary structure. In the case of 2-oxoisovalerate dehydrogenase (2OXO), sulfopyruvate decarboxylase (ComDE), and the E1 component of human pyruvate dehydrogenase complex (E1- PDHc) the PYR and PP domains appear on different subunits. TPP-dependent enzymes are multisubunit proteins, the smallest catalytic unit being a dimer-of-active sites. For many of these enzymes the active sites lie between PP and PYR domains on different subunits. However, for the homodimeric enzymes 1-deoxy-D-xylulose 5-phosphate synthase (DXS) and Desulfovibrio africanus pyruvate:ferredoxin oxidoreductase (PFOR), each active site lies at the interface of the PYR and PP domains from the same subunit.
Pssm-ID: 132915 [Multi-domain] Cd Length: 154 Bit Score: 102.04 E-value: 2.51e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 6 AAVSIMVDEGVDIAFGCPGAAILPLYKAMEEDGRIDHLTVRHEEGATHMADGWARTNGKvGVAIATSGPGATNLVTGLYT 85
Cdd:cd06586 2 AFAEVLTAWGVRHVFGYPGDEISSLLDALREGDKRIIDTVIHELGAAGAAAGYARAGGP-PVVIVTSGTGLLNAINGLAD 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1941825792 86 AQADSIPMVCLTGQAVSPKLHQEAFQAVDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAGrPGPVLIDLP 159
Cdd:cd06586 81 AAAEHLPVVFLIGARGISAQAKQTFQSMFDLGMYRSIPEANISSPSPAELPAGIDHAIRTAYAS-QGPVVVRLP 153
|
|
| TPP_POX |
cd02014 |
Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; ... |
363-550 |
1.00e-23 |
|
Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates pyruvate, producing hydrogen peroxide and the energy-storage metabolite acetylphosphate. It requires FAD in addition to TPP and a divalent cation as cofactors.
Pssm-ID: 238972 [Multi-domain] Cd Length: 178 Bit Score: 98.37 E-value: 1.00e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 363 PVKAPRAYKEINEAFDENTYFVTAIGLYQIWGGQHQKAYLPRHYQVCGQAGPLGWEVPAAIGVKKAlegmgEPDAEVVGI 442
Cdd:cd02014 1 PIHPERVAAELNKRAPDDAIFTIDVGNVTVWAARHLRMNGKQRFILSGLLATMGNGLPGAIAAKLA-----YPDRQVIAL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 443 VGDYGFQYLVEELAVAAQYNVPYVLIMLNNEYLGLIrQAEigygmnyQVDIHYDEFGTDN-----VKLMEAYGCSGQRVW 517
Cdd:cd02014 76 SGDGGFAMLMGDLITAVKYNLPVIVVVFNNSDLGFI-KWE-------QEVMGQPEFGVDLpnpdfAKIAEAMGIKGIRVE 147
|
170 180 190
....*....|....*....|....*....|...
gi 1941825792 518 EPADISGAIqwarKEAVATSRPVLVEIMIEREA 550
Cdd:cd02014 148 DPDELEAAL----DEALAADGPVVIDVVTDPNE 176
|
|
| TPP_BZL_OCoD_HPCL |
cd02004 |
Thiamine pyrophosphate (TPP) family, BZL_OCoD_HPCL subfamily, TPP-binding module; composed of ... |
368-547 |
1.05e-20 |
|
Thiamine pyrophosphate (TPP) family, BZL_OCoD_HPCL subfamily, TPP-binding module; composed of proteins similar to benzaldehyde lyase (BZL), oxalyl-CoA decarboxylase (OCoD) and 2-hydroxyphytanoyl-CoA lyase (2-HPCL). Pseudomonas fluorescens biovar I BZL cleaves the acyloin linkage of benzoin producing 2 molecules of benzaldehyde and enabling the Pseudomonas to grow on benzoin as the sole carbon and energy source. OCoD has a role in the detoxification of oxalate, catalyzing the decarboxylation of oxalyl-CoA to formate. 2-HPCL is a peroxisomal enzyme which plays a role in the alpha-oxidation of 3-methyl-branched fatty acids, catalyzing the cleavage of 2-hydroxy-3-methylacyl-CoA into formyl-CoA and a 2-methyl-branched fatty aldehyde. All these enzymes depend on Mg2+ and TPP for activity.
Pssm-ID: 238962 [Multi-domain] Cd Length: 172 Bit Score: 89.51 E-value: 1.05e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 368 RAYKEINEAFDENTYFVTAIGLYQIWGGQHQKAYLPRHYQVCGQAGPLGWEVPAAIGVKKAlegmgEPDAEVVGIVGDYG 447
Cdd:cd02004 3 RVLHELQEALPDDAIIVSDGGNTMDWARYILRPRKPRHRLDAGTFGTLGVGLGYAIAAALA-----RPDKRVVLVEGDGA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 448 FQYLVEELAVAAQYNVPYVLIMLNNEYLGLIR---QAEIGYGMNYQV---DIHYDefgtdnvKLMEAYGCSGQRVWEPAD 521
Cdd:cd02004 78 FGFSGMELETAVRYNLPIVVVVGNNGGWYQGLdgqQLSYGLGLPVTTllpDTRYD-------LVAEAFGGKGELVTTPEE 150
|
170 180
....*....|....*....|....*.
gi 1941825792 522 ISGAIqwarKEAVATSRPVLVEIMIE 547
Cdd:cd02004 151 LKPAL----KRALASGKPALINVIID 172
|
|
| TPP_BFDC |
cd02002 |
Thiamine pyrophosphate (TPP) family, BFDC subfamily, TPP-binding module; composed of proteins ... |
371-546 |
2.85e-20 |
|
Thiamine pyrophosphate (TPP) family, BFDC subfamily, TPP-binding module; composed of proteins similar to Pseudomonas putida benzoylformate decarboxylase (BFDC). P. putida BFDC plays a role in the mandelate pathway, catalyzing the conversion of benzoylformate to benzaldehyde and carbon dioxide. This enzyme is dependent on TPP and a divalent metal cation as cofactors.
Pssm-ID: 238960 [Multi-domain] Cd Length: 178 Bit Score: 88.42 E-value: 2.85e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 371 KEINEAFDENT-YFVTAIGLYQIWGGQHQKAYLPRHYQVCGqaGPLGWEVPAAIGVKkalegMGEPDAEVVGIVGDYGFQ 449
Cdd:cd02002 8 AALAAALPEDAiIVDEAVTNGLPLRDQLPLTRPGSYFTLRG--GGLGWGLPAAVGAA-----LANPDRKVVAIIGDGSFM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 450 YLVEELAVAAQYNVPYVLIMLNN-EYLGL----IRQAEIGYGMNYQVDIHYDEFGTDNVKLMEAYGCSGQRVWEPADISG 524
Cdd:cd02002 81 YTIQALWTAARYGLPVTVVILNNrGYGALrsflKRVGPEGPGENAPDGLDLLDPGIDFAAIAKAFGVEAERVETPEELDE 160
|
170 180
....*....|....*....|..
gi 1941825792 525 AIqwarKEAVATSRPVLVEIMI 546
Cdd:cd02002 161 AL----REALAEGGPALIEVVV 178
|
|
| PRK12474 |
PRK12474 |
hypothetical protein; Provisional |
1-219 |
4.61e-17 |
|
hypothetical protein; Provisional
Pssm-ID: 139002 [Multi-domain] Cd Length: 518 Bit Score: 84.15 E-value: 4.61e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 1 MPAMNAAVSI---MVDEGVDIAFGCPGAAILPLYKAMEEDGRIDHLTVRHEEGATHMADGWARTNGKVGVAIATSGPGAT 77
Cdd:PRK12474 2 GQTMNGADSVvdtLLNCGVEVCFANPGTSEMHFVAALDRVPRMRPVLCLFEGVVTGAADGYGRIAGKPAVTLLHLGPGLA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 78 NLVTGLYTAQADSIPMVCLTGQAVSPKLHQEAFQAVDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAGRPGPVLID 157
Cdd:PRK12474 82 NGLANLHNARRAASPIVNIVGDHAVEHLQYDAPLTSDIDGFARPVSRWVHRSASAGAVDSDVARAVQAAQSAPGGIATLI 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1941825792 158 LPLDLAKREITYDAEidtRLPVPAVEPHLPRVERALDMLLAAERPLILAGGGVILADAGSEL 219
Cdd:PRK12474 162 MPADVAWNEAAYAAQ---PLRGIGPAPVAAETVERIAALLRNGKKSALLLRGSALRGAPLEA 220
|
|
| PRK07586 |
PRK07586 |
acetolactate synthase large subunit; |
4-215 |
3.82e-16 |
|
acetolactate synthase large subunit;
Pssm-ID: 236063 [Multi-domain] Cd Length: 514 Bit Score: 81.43 E-value: 3.82e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 4 MNAAVSIM---VDEGVDIAFGCPGAAILPLYKAMEEDGRIDHLTVRHEEGATHMADGWARTNGKVGVAIATSGPGATNLV 80
Cdd:PRK07586 1 MNGAESLVrtlVDGGVDVCFANPGTSEMHFVAALDRVPGMRCVLGLFEGVATGAADGYARMAGKPAATLLHLGPGLANGL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 81 TGLYTAQADSIPMVCLTGQAVSPKLHQEAFQAVDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRIARAGRPGPVLIDLPL 160
Cdd:PRK07586 81 ANLHNARRARTPIVNIVGDHATYHRKYDAPLTSDIEALARPVSGWVRRSESAADVAADAAAAVAAARGAPGQVATLILPA 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1941825792 161 DLAKREITYDAEIDTRLPVPAVEPHlpRVERALDMLLAAERPLILAGGGVILADA 215
Cdd:PRK07586 161 DVAWSEGGPPAPPPPAPAPAAVDPA--AVEAAAAALRSGEPTVLLLGGRALRERG 213
|
|
| TPP_ALS |
cd02010 |
Thiamine pyrophosphate (TPP) family, Acetolactate synthase (ALS) subfamily, TPP-binding module; ... |
368-551 |
5.54e-16 |
|
Thiamine pyrophosphate (TPP) family, Acetolactate synthase (ALS) subfamily, TPP-binding module; composed of proteins similar to Klebsiella pneumoniae ALS, a catabolic enzyme required for butanediol fermentation. ALS catalyzes the conversion of 2 molecules of pyruvate to acetolactate and carbon dioxide. ALS does not contain FAD, and requires TPP and a divalent metal cation for activity.
Pssm-ID: 238968 [Multi-domain] Cd Length: 177 Bit Score: 76.17 E-value: 5.54e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 368 RAYKEINEAFDENTYFVTAIGLYQIWGGQHQKAYLPRHYQVCGQAGPLGWEVPAAIGVKkalegMGEPDAEVVGIVGDYG 447
Cdd:cd02010 3 RIVHDLRAVMGDDDIVLLDVGAHKIWMARYYRTYAPNTCLISNGLATMGVALPGAIGAK-----LVYPDRKVVAVSGDGG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 448 FQYLVEELAVAAQYNVPYVLIMLNNEYLGLIR-QAEIGYGMNYQVDihydeFG-TDNVKLMEAYGCSGQRVWEPADISGA 525
Cdd:cd02010 78 FMMNSQELETAVRLKIPLVVLIWNDNGYGLIKwKQEKEYGRDSGVD-----FGnPDFVKYAESFGAKGYRIESADDLLPV 152
|
170 180
....*....|....*....|....*.
gi 1941825792 526 IqwarKEAVATSRPVLVEIMIEREAN 551
Cdd:cd02010 153 L----ERALAADGVHVIDCPVDYSEN 174
|
|
| TPP_Xsc_like |
cd02013 |
Thiamine pyrophosphate (TPP) family, Xsc-like subfamily, TPP-binding module; composed of ... |
363-553 |
5.40e-15 |
|
Thiamine pyrophosphate (TPP) family, Xsc-like subfamily, TPP-binding module; composed of proteins similar to Alcaligenes defragrans sulfoacetaldehyde acetyltransferase (Xsc). Xsc plays a key role in the degradation of taurine, catalyzing the desulfonation of 2-sulfoacetaldehyde into sulfite and acetyl phosphate. This enzyme requires TPP and divalent metal ions for activity.
Pssm-ID: 238971 [Multi-domain] Cd Length: 196 Bit Score: 73.70 E-value: 5.40e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 363 PVKAPRAYKEINEAFDENTYFVTAIGLYQIWGGQHQKAYLPRHYQVCGQAGPLGWEVPAAIGVKkalegMGEPDAEVVGI 442
Cdd:cd02013 3 PMHPRQVLRELEKAMPEDAIVSTDIGNICSVANSYLRFEKPRSFIAPLSFGNCGYALPAIIGAK-----AAAPDRPVVAI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 443 VGDYGFQYLVEELAVAAQYNVPYVLIMLNNEYLGlirqAEigygMNYQVDIHYDEF-GTD-----NVKLMEAYGCSGQRV 516
Cdd:cd02013 78 AGDGAWGMSMMEIMTAVRHKLPVTAVVFRNRQWG----AE----KKNQVDFYNNRFvGTElesesFAKIAEACGAKGITV 149
|
170 180 190
....*....|....*....|....*....|....*..
gi 1941825792 517 WEPADISGAIQWArKEAVATSRPVLVEIMIEREANTP 553
Cdd:cd02013 150 DKPEDVGPALQKA-IAMMAEGKTTVIEIVCDQELGDP 185
|
|
| TPP_PYR_MenD |
cd07037 |
Pyrimidine (PYR) binding domain of ... |
9-160 |
8.06e-13 |
|
Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1-carboxylate synthase (MenD) and related proteins; Thiamine pyrophosphate (TPP family), pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1-carboxylate (SEPHCHC) synthase (MenD) subfamily. The PYR domain is found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. TPP binds in the cleft formed by a PYR domain and a PP domain. The PYR domain, binds the aminopyrimidine ring of TPP, the PP domain binds the diphosphate residue. The PYR and PP domains have a common fold, but do not share strong sequence conservation. The PP domain is not included in this sub-family. Most TPP-dependent enzymes have the PYR and PP domains on the same subunit although these domains can be alternatively arranged in the primary structure. TPP-dependent enzymes are multisubunit proteins, the smallest catalytic unit being a dimer-of-active sites. Escherichia coli MenD (EcMenD) is a homotetramer (dimer-of-homodimers), having two active sites per homodimer lying between PYR and PP domains of different subunits. EcMenD catalyzes a Stetter-like conjugate addition of alpha-ketoglutarate to isochorismate, leading to the formation of SEPHCHC and carbon dioxide, this addition is the first committed step in the biosynthesis of vitamin K2 (menaquinone).
Pssm-ID: 132920 [Multi-domain] Cd Length: 162 Bit Score: 66.37 E-value: 8.06e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 9 SIMVDE----GVDIAFGCPGAAILPLYKAMEEDGRIDHLTVRHEEGATHMADGWARTNGKVGVAIATSGPGATNLVTGLY 84
Cdd:cd07037 1 QALVEElkrlGVRDVVISPGSRSAPLALAAAEHPEFRLHVRVDERSAAFFALGLAKASGRPVAVVCTSGTAVANLLPAVV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 85 TAQADSIPMVCLTGQAVSPKLHQEAFQAVDIVEIAKPVTKWAVQIKEP------AQIPWAFREAFRIARAGRPGPVLIDL 158
Cdd:cd07037 81 EAYYSGVPLLVLTADRPPELRGTGANQTIDQVGLFGDYVRWSVDLPPPeddddlWYLLRLANRAVLEALSAPPGPVHLNL 160
|
..
gi 1941825792 159 PL 160
Cdd:cd07037 161 PF 162
|
|
| TPP_PYR_PDC_IPDC_like |
cd07038 |
Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase ... |
15-159 |
5.13e-11 |
|
Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Thiamine pyrophosphate (TPP family), pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC) subfamily. The PYR domain is found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. TPP binds in the cleft formed by a PYR domain and a PP domain. The PYR domain, binds the aminopyrimidine ring of TPP, the PP domain binds the diphosphate residue. The PYR and PP domains have a common fold, but do not share strong sequence conservation. The PP domain is not included in this sub-family. Most TPP-dependent enzymes have the PYR and PP domains on the same subunit although these domains can be alternatively arranged in the primary structure. TPP-dependent enzymes are multisubunit proteins, the smallest catalytic unit being a dimer-of-active sites, for many the active sites lie between PP and PYR domains on different subunits. PDC catalyzes the conversion of pyruvate to acetaldehyde and CO2 in alcoholic fermentation. IPDC plays a role in the indole-3-pyruvic acid (IPA) pathway in plants and various plant-associated bacteria, it catalyzes the decarboxylation of IPA to IAA. Also belonging to this group is Mycobacterium tuberculosis alpha-keto acid decarboxylase (MtKDC) which participates in amino acid degradation via the Ehrlich pathway, and Lactococcus lactis branched-chain keto acid decarboxylase (KdcA) an enzyme identified as being involved in cheese ripening, which exhibits a very broad substrate range in the decarboxylation and carboligation reactions.
Pssm-ID: 132921 [Multi-domain] Cd Length: 162 Bit Score: 61.36 E-value: 5.13e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 15 GVDIAFGCPGAAILPLYKAMEEDGRIDHLTVRHEEGATHMADGWARTNGkVGVAIATSGPGATNLVTGLYTAQADSIPMV 94
Cdd:cd07038 11 GVKHVFGVPGDYNLPLLDAIEENPGLRWVGNCNELNAGYAADGYARVKG-LGALVTTYGVGELSALNGIAGAYAEHVPVV 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 95 CLTG------QAVSPKLHQ-------EAFQavdivEIAKPVTKWAVQIKE----PAQIPWAFREAFRIARagrpgPVLID 157
Cdd:cd07038 90 HIVGapstkaQASGLLLHHtlgdgdfDVFL-----KMFEEITCAAARLTDpenaAEEIDRVLRTALRESR-----PVYIE 159
|
..
gi 1941825792 158 LP 159
Cdd:cd07038 160 IP 161
|
|
| TPP_IolD |
cd02003 |
Thiamine pyrophosphate (TPP) family, IolD subfamily, TPP-binding module; composed of proteins ... |
373-544 |
6.31e-10 |
|
Thiamine pyrophosphate (TPP) family, IolD subfamily, TPP-binding module; composed of proteins similar to Rhizobium leguminosarum bv. viciae IolD. IolD plays an important role in myo-inositol catabolism.
Pssm-ID: 238961 [Multi-domain] Cd Length: 205 Bit Score: 59.24 E-value: 6.31e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 373 INEAFDENTYFVTAIG-----LYQIWggqhqKAYLPRHYQV-----CgqagpLGWEVPAAIGVKkalegMGEPDAEVVGI 442
Cdd:cd02003 8 LNEAIGDDDVVINAAGslpgdLHKLW-----RARTPGGYHLeygysC-----MGYEIAAGLGAK-----LAKPDREVYVL 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 443 VGDYGFQYLVEELAVAAQYNVPYVLIMLNNEYLGLIRQAEIGYGM-------NYQVDIHYDEFG----TDNVKLMEAYGC 511
Cdd:cd02003 73 VGDGSYLMLHSEIVTAVQEGLKIIIVLFDNHGFGCINNLQESTGSgsfgtefRDRDQESGQLDGallpVDFAANARSLGA 152
|
170 180 190
....*....|....*....|....*....|...
gi 1941825792 512 sgqRVWEPADISGAIQwARKEAVATSRPVLVEI 544
Cdd:cd02003 153 ---RVEKVKTIEELKA-ALAKAKASDRTTVIVI 181
|
|
| TPP_PDC_IPDC |
cd02005 |
Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of ... |
363-549 |
1.20e-08 |
|
Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of pyruvate to acetaldehyde and CO2. It is able to utilize other 2-oxo acids as substrates. In plants and various plant-associated bacteria, IPDC plays a role in the indole-3-pyruvic acid (IPA) pathway, a tryptophan-dependent biosynthetic route to indole-3-acetaldehyde (IAA). IPDC catalyzes the decarboxylation of IPA to IAA. Both PDC and IPDC depend on TPP and Mg2+ as cofactors.
Pssm-ID: 238963 [Multi-domain] Cd Length: 183 Bit Score: 54.85 E-value: 1.20e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 363 PVKAPRAYKEINEAFDENTYFVTAIGLYQIwGGQHQKayLPRHYQVCGQA--GPLGWEVPAAIGVkkaleGMGEPDAEVV 440
Cdd:cd02005 1 PLTQARLWQQVQNFLKPNDILVAETGTSWF-GALDLK--LPKGTRFISQPlwGSIGYSVPAALGA-----ALAAPDRRVI 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 441 GIVGDYGFQYLVEELAVAAQYNVPYVLIMLNNEylglirqaeiGYGMnyQVDIHYDEFGTDNV------KLMEAYGCSGQ 514
Cdd:cd02005 73 LLVGDGSFQMTVQELSTMIRYGLNPIIFLINND----------GYTI--ERAIHGPEASYNDIanwnytKLPEVFGGGGG 140
|
170 180 190
....*....|....*....|....*....|....*....
gi 1941825792 515 ----RVWEPADISGAIQWARKEavaTSRPVLVEIMIERE 549
Cdd:cd02005 141 glsfRVKTEGELDEALKDALFN---RDKLSLIEVILPKD 176
|
|
| TPP_E1_PDC_ADC_BCADC |
cd02000 |
Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; ... |
394-545 |
3.45e-03 |
|
Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain alpha-keto acid dehydrogenase/2-oxoisovalerate dehydrogenase complex (BCADC). PDC catalyzes the irreversible oxidative decarboxylation of pyruvate to produce acetyl-CoA in the bridging step between glycolysis and the citric acid cycle. ADC participates in the breakdown of acetoin while BCADC participates in the breakdown of branched chain amino acids. BCADC catalyzes the oxidative decarboxylation of 4-methyl-2-oxopentanoate, 3-methyl-2-oxopentanoate and 3-methyl-2-oxobutanoate (branched chain 2-oxo acids derived from the transamination of leucine, valine and isoleucine).
Pssm-ID: 238958 [Multi-domain] Cd Length: 293 Bit Score: 39.79 E-value: 3.45e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941825792 394 GGQHQKAYLPRHYQVCGQAGPLGWEVPAAIGVKKALEGMGEPDAeVVGIVGDYG-----FQylvEELAVAAQYNVPYVLI 468
Cdd:cd02000 85 GRGGSMHIGDKEKNFFGGNGIVGGQVPLAAGAALALKYRGEDRV-AVCFFGDGAtnegdFH---EALNFAALWKLPVIFV 160
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1941825792 469 MLNNeylglirqaeiGYGMNYQVDIHYDefGTDNVKLMEAYGCSGQRV--WEPADISGAIQWARKEAVATSRPVLVEIM 545
Cdd:cd02000 161 CENN-----------GYAISTPTSRQTA--GTSIADRAAAYGIPGIRVdgNDVLAVYEAAKEAVERARAGGGPTLIEAV 226
|
|
| PRK06546 |
PRK06546 |
pyruvate dehydrogenase; Provisional |
113-161 |
6.32e-03 |
|
pyruvate dehydrogenase; Provisional
Pssm-ID: 180614 [Multi-domain] Cd Length: 578 Bit Score: 39.20 E-value: 6.32e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 1941825792 113 VDIVEIAKPVTKWAVQIKEPAQIPWAFREAFRiaragRPGPVLIDLPLD 161
Cdd:PRK06546 487 VDYAAIAAALGIHAVRVEDPKDVRGALREAFA-----HPGPALVDVVTD 530
|
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| |
