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Conserved domains on  [gi|1938979348|gb|QPK53656|]
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glycosyltransferase [Paenibacillus polymyxa]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
WcaA COG0463
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ...
 6-118 3.43e-14

Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 440231 [Multi-domain]  Cd Length: 208  Bit Score: 70.89  E-value: 3.43e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938979348   6 IVMPLYKQDiGYLQAAISSVLAQSYRAFRFIIVIDGAP----EMIEPAlhaAMGDPRVQLVTLPQNQGVSHALNRGFDEL 81
Cdd:COG0463     6 VVIPTYNEE-EYLEEALESLLAQTYPDFEIIVVDDGSTdgtaEILREL---AAKDPRIRVIRLERNRGKGAARNAGLAAA 81

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1938979348  82 FKDpaikYVTWVSSDNVYHSSFIERLRCELERGPDSL 118
Cdd:COG0463    82 RGD----YIAFLDADDQLDPEKLEELVAALEEGPADL 114
BcsA COG1215
Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1, ...
 6-256 1.51e-11

Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility];


:

Pssm-ID: 440828 [Multi-domain]  Cd Length: 303  Bit Score: 64.76  E-value: 1.51e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938979348   6 IVMPLYKQDIgYLQAAISSVLAQSYRAFRF-IIVI-----DGAPEMIEpalHAAMGDPRVQLVTLPQNQGVSHALNRGFD 79
Cdd:COG1215    33 VIIPAYNEEA-VIEETLRSLLAQDYPKEKLeVIVVddgstDETAEIAR---ELAAEYPRVRVIERPENGGKAAALNAGLK 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938979348  80 ElfkdPAIKYVTWVSSDNVYHSSFIERlrcelergpdslglvfstfrqidaagnplydqqhqqaLIRYQSQPhhellNAS 159
Cdd:COG1215   109 A----ARGDIVVFLDADTVLDPDWLRR-------------------------------------LVAAFADP-----GVG 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938979348 160 IVGVSFMYKSQYARLIDGYRLQPV-EDYDYWLRLTET-CNMKFIPEILMDYRVDSAFSvsaSLRSQKehRRW-RHAFQIA 236
Cdd:COG1215   143 ASGANLAFRREALEEVGGFDEDTLgEDLDLSLRLLRAgYRIVYVPDAVVYEEAPETLR---ALFRQR--RRWaRGGLQLL 217

                         250       260
                  ....*....|....*....|...
gi 1938979348 237 KHEARARRGIPLE---MTILMPI 256
Cdd:COG1215   218 LKHRPLLRPRRLLlflLLLLLPL 240
 
Name Accession Description Interval E-value
WcaA COG0463
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ...
 6-118 3.43e-14

Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440231 [Multi-domain]  Cd Length: 208  Bit Score: 70.89  E-value: 3.43e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938979348   6 IVMPLYKQDiGYLQAAISSVLAQSYRAFRFIIVIDGAP----EMIEPAlhaAMGDPRVQLVTLPQNQGVSHALNRGFDEL 81
Cdd:COG0463     6 VVIPTYNEE-EYLEEALESLLAQTYPDFEIIVVDDGSTdgtaEILREL---AAKDPRIRVIRLERNRGKGAARNAGLAAA 81

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1938979348  82 FKDpaikYVTWVSSDNVYHSSFIERLRCELERGPDSL 118
Cdd:COG0463    82 RGD----YIAFLDADDQLDPEKLEELVAALEEGPADL 114
Glyco_tranf_GTA_type cd00761
Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a ...
 6-116 5.99e-13

Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.


Pssm-ID: 132997 [Multi-domain]  Cd Length: 156  Bit Score: 65.99  E-value: 5.99e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938979348   6 IVMPLYKqDIGYLQAAISSVLAQSYRAFRFIIVIDGAPEMIEPALHA-AMGDPRVQLVTLPQNQGVSHALNRGFDELFKD 84
Cdd:cd00761     1 VIIPAYN-EEPYLERCLESLLAQTYPNFEVIVVDDGSTDGTLEILEEyAKKDPRVIRVINEENQGLAAARNAGLKAARGE 79

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1938979348  85 paikYVTWVSSDNVYHSSFIERLRCELERGPD 116
Cdd:cd00761    80 ----YILFLDADDLLLPDWLERLVAELLADPE 107
BcsA COG1215
Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1, ...
 6-256 1.51e-11

Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility];


Pssm-ID: 440828 [Multi-domain]  Cd Length: 303  Bit Score: 64.76  E-value: 1.51e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938979348   6 IVMPLYKQDIgYLQAAISSVLAQSYRAFRF-IIVI-----DGAPEMIEpalHAAMGDPRVQLVTLPQNQGVSHALNRGFD 79
Cdd:COG1215    33 VIIPAYNEEA-VIEETLRSLLAQDYPKEKLeVIVVddgstDETAEIAR---ELAAEYPRVRVIERPENGGKAAALNAGLK 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938979348  80 ElfkdPAIKYVTWVSSDNVYHSSFIERlrcelergpdslglvfstfrqidaagnplydqqhqqaLIRYQSQPhhellNAS 159
Cdd:COG1215   109 A----ARGDIVVFLDADTVLDPDWLRR-------------------------------------LVAAFADP-----GVG 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938979348 160 IVGVSFMYKSQYARLIDGYRLQPV-EDYDYWLRLTET-CNMKFIPEILMDYRVDSAFSvsaSLRSQKehRRW-RHAFQIA 236
Cdd:COG1215   143 ASGANLAFRREALEEVGGFDEDTLgEDLDLSLRLLRAgYRIVYVPDAVVYEEAPETLR---ALFRQR--RRWaRGGLQLL 217

                         250       260
                  ....*....|....*....|...
gi 1938979348 237 KHEARARRGIPLE---MTILMPI 256
Cdd:COG1215   218 LKHRPLLRPRRLLlflLLLLLPL 240
Glycos_transf_2 pfam00535
Glycosyl transferase family 2; Diverse family, transferring sugar from UDP-glucose, ...
 6-107 6.00e-11

Glycosyl transferase family 2; Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.


Pssm-ID: 425738 [Multi-domain]  Cd Length: 166  Bit Score: 60.49  E-value: 6.00e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938979348   6 IVMPLYkQDIGYLQAAISSVLAQSYRAFRFIIVIDG----APEMIEPALHAamgDPRVQLVTLPQNQGVSHALNRGFDEL 81
Cdd:pfam00535   2 VIIPTY-NEEKYLLETLESLLNQTYPNFEIIVVDDGstdgTVEIAEEYAKK---DPRVRVIRLPENRGKAGARNAGLRAA 77

                          90       100
                  ....*....|....*....|....*.
gi 1938979348  82 FKDpaikYVTWVSSDNVYHSSFIERL 107
Cdd:pfam00535  78 TGD----YIAFLDADDEVPPDWLEKL 99
PRK10073 PRK10073
putative glycosyl transferase; Provisional
 6-107 6.05e-06

putative glycosyl transferase; Provisional


Pssm-ID: 182223 [Multi-domain]  Cd Length: 328  Bit Score: 47.73  E-value: 6.05e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938979348   6 IVMPLYKQDiGYLQAAISSVLAQSYRAFRFIIVIDGAP-EMIEPALHAAMGDPRVQLVTlPQNQGVSHALNRGFdelfkd 84
Cdd:PRK10073   10 IIIPLYNAG-KDFRAFMESLIAQTWTALEIIIVNDGSTdNSVEIAKHYAENYPHVRLLH-QANAGVSVARNTGL------ 81

                          90       100
                  ....*....|....*....|....*.
gi 1938979348  85 pAI---KYVTWVSSDNVYHSSFIERL 107
Cdd:PRK10073   82 -AVatgKYVAFPDADDVVYPTMYETL 106
Glyco_tranf_2_3 pfam13641
Glycosyltransferase like family 2; Members of this family of prokaryotic proteins include ...
 3-229 6.00e-03

Glycosyltransferase like family 2; Members of this family of prokaryotic proteins include putative glucosyltransferase, which are involved in bacterial capsule biosynthesis.


Pssm-ID: 433372 [Multi-domain]  Cd Length: 230  Bit Score: 38.12  E-value: 6.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938979348   3 DTGIVMPLYKQDiGYLQAAISSVLAQSYRAFRFIIVIDGAP-EMIEPALHAAMGDPRVQLVTLPQNQ-----GVSHALNR 76
Cdd:pfam13641   3 DVSVVVPAFNED-SVLGRVLEAILAQPYPPVEVVVVVNPSDaETLDVAEEIAARFPDVRLRVIRNARllgptGKSRGLNH 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938979348  77 GFdelfkdPAIK--YVTWVSSDNVYHSSFIERLrcelergpdslgLVFSTFRQIDAAGNPlydqQHQQALIRYQSQPH-- 152
Cdd:pfam13641  82 GF------RAVKsdLVVLHDDDSVLHPGTLKKY------------VQYFDSPKVGAVGTP----VFSLNRSTMLSALGal 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938979348 153 -------------HELLNASIVGVSFMYKSQYARLIDGYRLQPV--EDYDYWLRLTET-CNMKFIPEILMdyRVDSAFSV 216
Cdd:pfam13641 140 efalrhlrmmslrLALGVLPLSGAGSAIRREVLKELGLFDPFFLlgDDKSLGRRLRRHgWRVAYAPDAAV--RTVFPTYL 217

                         250
                  ....*....|...
gi 1938979348 217 SASLRsqkEHRRW 229
Cdd:pfam13641 218 AASIK---QRARW 227
 
Name Accession Description Interval E-value
WcaA COG0463
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ...
 6-118 3.43e-14

Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440231 [Multi-domain]  Cd Length: 208  Bit Score: 70.89  E-value: 3.43e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938979348   6 IVMPLYKQDiGYLQAAISSVLAQSYRAFRFIIVIDGAP----EMIEPAlhaAMGDPRVQLVTLPQNQGVSHALNRGFDEL 81
Cdd:COG0463     6 VVIPTYNEE-EYLEEALESLLAQTYPDFEIIVVDDGSTdgtaEILREL---AAKDPRIRVIRLERNRGKGAARNAGLAAA 81

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1938979348  82 FKDpaikYVTWVSSDNVYHSSFIERLRCELERGPDSL 118
Cdd:COG0463    82 RGD----YIAFLDADDQLDPEKLEELVAALEEGPADL 114
Glyco_tranf_GTA_type cd00761
Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a ...
 6-116 5.99e-13

Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.


Pssm-ID: 132997 [Multi-domain]  Cd Length: 156  Bit Score: 65.99  E-value: 5.99e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938979348   6 IVMPLYKqDIGYLQAAISSVLAQSYRAFRFIIVIDGAPEMIEPALHA-AMGDPRVQLVTLPQNQGVSHALNRGFDELFKD 84
Cdd:cd00761     1 VIIPAYN-EEPYLERCLESLLAQTYPNFEVIVVDDGSTDGTLEILEEyAKKDPRVIRVINEENQGLAAARNAGLKAARGE 79

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1938979348  85 paikYVTWVSSDNVYHSSFIERLRCELERGPD 116
Cdd:cd00761    80 ----YILFLDADDLLLPDWLERLVAELLADPE 107
GT2_AmsE_like cd04195
GT2_AmsE_like is involved in exopolysaccharide amylovora biosynthesis; AmsE is a ...
 6-209 2.72e-12

GT2_AmsE_like is involved in exopolysaccharide amylovora biosynthesis; AmsE is a glycosyltransferase involved in exopolysaccharide amylovora biosynthesis in Erwinia amylovora. Amylovara is one of the three exopolysaccharide produced by E. amylovora. Amylovara-deficient mutants are non-pathogenic. It is a subfamily of Glycosyltransferase Family GT2, which includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds.


Pssm-ID: 133038 [Multi-domain]  Cd Length: 201  Bit Score: 65.41  E-value: 2.72e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938979348   6 IVMPLY-KQDIGYLQAAISSVLAQSYRAFRFIIVIDGA-PEMIEPALHAAMGDPRVQLVTLPQNQGVSHALNRGFDELFK 83
Cdd:cd04195     2 VLMSVYiKEKPEFLREALESILKQTLPPDEVVLVKDGPvTQSLNEVLEEFKRKLPLKVVPLEKNRGLGKALNEGLKHCTY 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938979348  84 DpaikYVTWVSSDNVyhsSFIERLRCEL---ERGPDsLGLVFSTFRQIDAAGNPLydqqhqqaLIRYQSQPHHELLNASI 160
Cdd:cd04195    82 D----WVARMDTDDI---SLPDRFEKQLdfiEKNPE-IDIVGGGVLEFDSDGNDI--------GKRRLPTSHDDILKFAR 145

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1938979348 161 VGVSF-----MYKSQYARLIDGYRLQP-VEDYDYWLR-LTETCNMKFIPEILMDYR 209
Cdd:cd04195   146 RRSPFnhptvMFRKSKVLAVGGYQDLPlVEDYALWARmLANGARFANLPEILVKAR 201
BcsA COG1215
Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1, ...
 6-256 1.51e-11

Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility];


Pssm-ID: 440828 [Multi-domain]  Cd Length: 303  Bit Score: 64.76  E-value: 1.51e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938979348   6 IVMPLYKQDIgYLQAAISSVLAQSYRAFRF-IIVI-----DGAPEMIEpalHAAMGDPRVQLVTLPQNQGVSHALNRGFD 79
Cdd:COG1215    33 VIIPAYNEEA-VIEETLRSLLAQDYPKEKLeVIVVddgstDETAEIAR---ELAAEYPRVRVIERPENGGKAAALNAGLK 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938979348  80 ElfkdPAIKYVTWVSSDNVYHSSFIERlrcelergpdslglvfstfrqidaagnplydqqhqqaLIRYQSQPhhellNAS 159
Cdd:COG1215   109 A----ARGDIVVFLDADTVLDPDWLRR-------------------------------------LVAAFADP-----GVG 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938979348 160 IVGVSFMYKSQYARLIDGYRLQPV-EDYDYWLRLTET-CNMKFIPEILMDYRVDSAFSvsaSLRSQKehRRW-RHAFQIA 236
Cdd:COG1215   143 ASGANLAFRREALEEVGGFDEDTLgEDLDLSLRLLRAgYRIVYVPDAVVYEEAPETLR---ALFRQR--RRWaRGGLQLL 217

                         250       260
                  ....*....|....*....|...
gi 1938979348 237 KHEARARRGIPLE---MTILMPI 256
Cdd:COG1215   218 LKHRPLLRPRRLLlflLLLLLPL 240
GT2_RfbC_Mx_like cd04184
Myxococcus xanthus RfbC like proteins are required for O-antigen biosynthesis; The rfbC gene ...
 6-210 4.57e-11

Myxococcus xanthus RfbC like proteins are required for O-antigen biosynthesis; The rfbC gene encodes a predicted protein of 1,276 amino acids, which is required for O-antigen biosynthesis in Myxococcus xanthus. It is a subfamily of Glycosyltransferase Family GT2, which includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds.


Pssm-ID: 133027 [Multi-domain]  Cd Length: 202  Bit Score: 61.84  E-value: 4.57e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938979348   6 IVMPLYKQDIGYLQAAISSVLAQSYRAFRFIIVIDG--APEMIEPALHAAMGDPRVQLVTLPQNQGVSHALNRGFdELFK 83
Cdd:cd04184     5 IVMPVYNTPEKYLREAIESVRAQTYPNWELCIADDAstDPEVKRVLKKYAAQDPRIKVVFREENGGISAATNSAL-ELAT 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938979348  84 DpaiKYVTWVSSDNVYHS-SFIERLRcELERGPDsLGLVFSTFRQIDAAGNplydqqhqqaliryQSQPH------HELL 156
Cdd:cd04184    84 G---EFVALLDHDDELAPhALYEVVK-ALNEHPD-ADLIYSDEDKIDEGGK--------------RSEPFfkpdwsPDLL 144

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1938979348 157 nasivgVSFMYKSQYA-------RLIDGYR--LQPVEDYDYWLRLTE-TCNMKFIPEILMDYRV 210
Cdd:cd04184   145 ------LSQNYIGHLLvyrrslvRQVGGFRegFEGAQDYDLVLRVSEhTDRIAHIPRVLYHWRA 202
WcaE COG1216
Glycosyltransferase, GT2 family [Carbohydrate transport and metabolism];
1-107 4.65e-11

Glycosyltransferase, GT2 family [Carbohydrate transport and metabolism];


Pssm-ID: 440829 [Multi-domain]  Cd Length: 202  Bit Score: 61.55  E-value: 4.65e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938979348   1 MVDTGIVMPLYKQDiGYLQAAISSVLAQSYRAFRfIIVIDGAPEMIEPALHAAMGDPRVQLVTLPQNQGVSHALNRGFDE 80
Cdd:COG1216     2 RPKVSVVIPTYNRP-ELLRRCLESLLAQTYPPFE-VIVVDNGSTDGTAELLAALAFPRVRVIRNPENLGFAAARNLGLRA 79

                          90       100
                  ....*....|....*....|....*..
gi 1938979348  81 LfkdpAIKYVTWVSSDNVYHSSFIERL 107
Cdd:COG1216    80 A----GGDYLLFLDDDTVVEPDWLERL 102
Glycos_transf_2 pfam00535
Glycosyl transferase family 2; Diverse family, transferring sugar from UDP-glucose, ...
 6-107 6.00e-11

Glycosyl transferase family 2; Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.


Pssm-ID: 425738 [Multi-domain]  Cd Length: 166  Bit Score: 60.49  E-value: 6.00e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938979348   6 IVMPLYkQDIGYLQAAISSVLAQSYRAFRFIIVIDG----APEMIEPALHAamgDPRVQLVTLPQNQGVSHALNRGFDEL 81
Cdd:pfam00535   2 VIIPTY-NEEKYLLETLESLLNQTYPNFEIIVVDDGstdgTVEIAEEYAKK---DPRVRVIRLPENRGKAGARNAGLRAA 77

                          90       100
                  ....*....|....*....|....*.
gi 1938979348  82 FKDpaikYVTWVSSDNVYHSSFIERL 107
Cdd:pfam00535  78 TGD----YIAFLDADDEVPPDWLEKL 99
GT_2_WfgS_like cd06433
WfgS and WfeV are involved in O-antigen biosynthesis; Escherichia coli WfgS and Shigella ...
 6-211 5.30e-08

WfgS and WfeV are involved in O-antigen biosynthesis; Escherichia coli WfgS and Shigella dysenteriae WfeV are glycosyltransferase 2 family enzymes involved in O-antigen biosynthesis. GT-2 enzymes have GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.


Pssm-ID: 133055 [Multi-domain]  Cd Length: 202  Bit Score: 52.93  E-value: 5.30e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938979348   6 IVMPLYKQDiGYLQAAISSVLAQSYRAFRfIIVIDGAP-----EMIEpalhaAMGDPRVQLVTLPqNQGVSHALNRGFDE 80
Cdd:cd06433     2 IITPTYNQA-ETLEETIDSVLSQTYPNIE-YIVIDGGStdgtvDIIK-----KYEDKITYWISEP-DKGIYDAMNKGIAL 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938979348  81 lfkdpAI-KYVTWVSSDNVYHSSFIERLRCELERGPDSlGLVFSTFRQIDAAGN---PLYDQQHQQALIRYQSQPHHEll 156
Cdd:cd06433    74 -----ATgDIIGFLNSDDTLLPGALLAVVAAFAEHPEV-DVVYGDVLLVDENGRvigRRRPPPFLDKFLLYGMPICHQ-- 145

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1938979348 157 nasivgvSFMYKSQYARLIDGYR--LQPVEDYDYWLRL-TETCNMKFIPEILMDYRVD 211
Cdd:cd06433   146 -------ATFFRRSLFEKYGGFDesYRIAADYDLLLRLlLAGKIFKYLPEVLAAFRLG 196
CESA_like cd06423
CESA_like is the cellulose synthase superfamily; The cellulose synthase (CESA) superfamily ...
 20-179 1.14e-06

CESA_like is the cellulose synthase superfamily; The cellulose synthase (CESA) superfamily includes a wide variety of glycosyltransferase family 2 enzymes that share the common characteristic of catalyzing the elongation of polysaccharide chains. The members include cellulose synthase catalytic subunit, chitin synthase, glucan biosynthesis protein and other families of CESA-like proteins. Cellulose synthase catalyzes the polymerization reaction of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues in plants, most algae, some bacteria and fungi, and even some animals. In bacteria, algae and lower eukaryotes, there is a second unrelated type of cellulose synthase (Type II), which produces acylated cellulose, a derivative of cellulose. Chitin synthase catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin, which is a linear homopolymer of beta-(1,4)-linked GlcNAc residues and Glucan Biosynthesis protein catalyzes the elongation of beta-1,2 polyglucose chains of Glucan.


Pssm-ID: 133045 [Multi-domain]  Cd Length: 180  Bit Score: 48.38  E-value: 1.14e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938979348  20 AAISSVLAQSYRAFRFIIVIDGA-PEMIEPALH-AAMGDPRVQLVTLPQNQGVSHALNRGFdELFKDPaikYVTWVSSDN 97
Cdd:cd06423    14 RTIESLLALDYPKLEVIVVDDGStDDTLEILEElAALYIRRVLVVRDKENGGKAGALNAGL-RHAKGD---IVVVLDADT 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938979348  98 VYHSSFIERLRCELERGPDsLGLVFSTFRQIDAAGNPLYDQQH-QQALIRYQSQPHHELLNASIV--GVSFMYKSQYARL 174
Cdd:cd06423    90 ILEPDALKRLVVPFFADPK-VGAVQGRVRVRNGSENLLTRLQAiEYLSIFRLGRRAQSALGGVLVlsGAFGAFRREALRE 168


                  ....*
gi 1938979348 175 IDGYR 179
Cdd:cd06423   169 VGGWD 173
GT_2_like_d cd04196
Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse ...
 6-209 4.91e-06

Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.


Pssm-ID: 133039 [Multi-domain]  Cd Length: 214  Bit Score: 47.24  E-value: 4.91e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938979348   6 IVMPLYKqdiG--YLQAAISSVLAQSYRAFRFIIVIDGAP----EMIEpALHAAMGDPRVqLVTLPQNQGVshalNRGFD 79
Cdd:cd04196     2 VLMATYN---GekYLREQLDSILAQTYKNDELIISDDGSTdgtvEIIK-EYIDKDPFIII-LIRNGKNLGV----ARNFE 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938979348  80 ELFKDPAIKYVTWVSSDNVYHSSFIERLrCELERGPDSLGLVFSTFRQIDAAGNPLYDQQHQQALIRYQSQPHHELLNAS 159
Cdd:cd04196    73 SLLQAADGDYVFFCDQDDIWLPDKLERL-LKAFLKDDKPLLVYSDLELVDENGNPIGESFFEYQKIKPGTSFNNLLFQNV 151

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1938979348 160 IVGVSFMYKSQYARLIDGYRLQPVEDYDYWLRLTETC--NMKFIPEILMDYR 209
Cdd:cd04196   152 VTGCTMAFNRELLELALPFPDADVIMHDWWLALLASAfgKVVFLDEPLILYR 203
PRK10073 PRK10073
putative glycosyl transferase; Provisional
 6-107 6.05e-06

putative glycosyl transferase; Provisional


Pssm-ID: 182223 [Multi-domain]  Cd Length: 328  Bit Score: 47.73  E-value: 6.05e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938979348   6 IVMPLYKQDiGYLQAAISSVLAQSYRAFRFIIVIDGAP-EMIEPALHAAMGDPRVQLVTlPQNQGVSHALNRGFdelfkd 84
Cdd:PRK10073   10 IIIPLYNAG-KDFRAFMESLIAQTWTALEIIIVNDGSTdNSVEIAKHYAENYPHVRLLH-QANAGVSVARNTGL------ 81

                          90       100
                  ....*....|....*....|....*.
gi 1938979348  85 pAI---KYVTWVSSDNVYHSSFIERL 107
Cdd:PRK10073   82 -AVatgKYVAFPDADDVVYPTMYETL 106
GT_2_like_c cd04186
Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse ...
 6-116 1.35e-04

Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.


Pssm-ID: 133029 [Multi-domain]  Cd Length: 166  Bit Score: 42.16  E-value: 1.35e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938979348   6 IVMPLYKQdIGYLQAAISSVLAQSYRAFRFIIV----IDGAPEMIEPALhaamgdPRVQLVTLPQNQGVSHALNRGfdel 81
Cdd:cd04186     1 IIIVNYNS-LEYLKACLDSLLAQTYPDFEVIVVdnasTDGSVELLRELF------PEVRLIRNGENLGFGAGNNQG---- 69

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1938979348  82 FKDPAIKYVTWVSSDNVYHSSFIERLRCELERGPD 116
Cdd:cd04186    70 IREAKGDYVLLLNPDTVVEPGALLELLDAAEQDPD 104
DPM_DPG-synthase_like cd04179
DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; DPM1 is the ...
 6-80 4.45e-04

DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; DPM1 is the catalytic subunit of eukaryotic dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. In higher eukaryotes,the enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. In lower eukaryotes, such as Saccharomyces cerevisiae and Trypanosoma brucei, DPM synthase consists of a single component (Dpm1p and TbDpm1, respectively) that possesses one predicted transmembrane region near the C terminus for anchoring to the ER membrane. In contrast, the Dpm1 homologues of higher eukaryotes, namely fission yeast, fungi, and animals, have no transmembrane region, suggesting the existence of adapter molecules for membrane anchoring. This family also includes bacteria and archaea DPM1_like enzymes. However, the enzyme structure and mechanism of function are not well understood. The UDP-glucose:dolichyl-phosphate glucosyltransferase (DPG_synthase) is a transmembrane-bound enzyme of the endoplasmic reticulum involved in protein N-linked glycosylation. This enzyme catalyzes the transfer of glucose from UDP-glucose to dolichyl phosphate. This protein family belongs to Glycosyltransferase 2 superfamily.


Pssm-ID: 133022 [Multi-domain]  Cd Length: 185  Bit Score: 41.02  E-value: 4.45e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938979348   6 IVMPLYK--QDIGYLQAAISSVLAQSYRaFRFIIVIDGAP----EMIEpALHAAmgDPRVQLVTLPQNQGVSHALNRGFD 79
Cdd:cd04179     1 VVIPAYNeeENIPELVERLLAVLEEGYD-YEIIVVDDGSTdgtaEIAR-ELAAR--VPRVRVIRLSRNFGKGAAVRAGFK 76


                  .
gi 1938979348  80 E 80
Cdd:cd04179    77 A 77
GT_2_like_b cd04185
Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse ...
 17-107 1.29e-03

Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.


Pssm-ID: 133028 [Multi-domain]  Cd Length: 202  Bit Score: 39.54  E-value: 1.29e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938979348  17 YLQAAISSVLAQSYRAFRFIIV----IDGAPEMIEpALHaamGDPRVQLVTLPQNQG--------VSHALNRGFDelfkd 84
Cdd:cd04185    11 LLKECLDALLAQTRPPDHIIVIdnasTDGTAEWLT-SLG---DLDNIVYLRLPENLGgaggfyegVRRAYELGYD----- 81

                          90       100
                  ....*....|....*....|....
gi 1938979348  85 paikYVtWVSSDNVY-HSSFIERL 107
Cdd:cd04185    82 ----WI-WLMDDDAIpDPDALEKL 100
GT2_RfbF_like cd02526
RfbF is a putative dTDP-rhamnosyl transferase; Shigella flexneri RfbF protein is a putative ...
 10-111 1.60e-03

RfbF is a putative dTDP-rhamnosyl transferase; Shigella flexneri RfbF protein is a putative dTDP-rhamnosyl transferase. dTDP rhamnosyl transferases of Shigella flexneri add rhamnose sugars to N-acetyl-glucosamine in the O-antigen tetrasaccharide repeat. Lipopolysaccharide O antigens are important virulence determinants for many bacteria. The variations of sugar composition, the sequence of the sugars and the linkages in the O antigen provide structural diversity of the O antigen.


Pssm-ID: 133017 [Multi-domain]  Cd Length: 237  Bit Score: 39.57  E-value: 1.60e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938979348  10 LYKQDIGYLQAAISSVLAQSYRafrfIIVIDGAPEmIEPALHAAMGDPRVQLVTLPQNQGVSHALNRGFDELFKDPAiKY 89
Cdd:cd02526     5 TYNPDLSKLKELLAALAEQVDK----VVVVDNSSG-NDIELRLRLNSEKIELIHLGENLGIAKALNIGIKAALENGA-DY 78

                          90       100
                  ....*....|....*....|..
gi 1938979348  90 VTWVSSDNVYHSSFIERLRCEL 111
Cdd:cd02526    79 VLLFDQDSVPPPDMVEKLLAYK 100
DPM1_like_bac cd04187
Bacterial DPM1_like enzymes are related to eukaryotic DPM1; A family of bacterial enzymes ...
 6-79 1.73e-03

Bacterial DPM1_like enzymes are related to eukaryotic DPM1; A family of bacterial enzymes related to eukaryotic DPM1; Although the mechanism of eukaryotic enzyme is well studied, the mechanism of the bacterial enzymes is not well understood. The eukaryotic DPM1 is the catalytic subunit of eukaryotic Dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. The enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. This protein family belongs to Glycosyltransferase 2 superfamily.


Pssm-ID: 133030 [Multi-domain]  Cd Length: 181  Bit Score: 39.00  E-value: 1.73e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938979348   6 IVMPLYK--QDIGYLQAAISSVLAQSYRAFRFIIVIDGAP----EMIEpALHAAmgDPRVQLVTLPQNQGVSHALNRGFD 79
Cdd:cd04187     1 IVVPVYNeeENLPELYERLKAVLESLGYDYEIIFVDDGSTdrtlEILR-ELAAR--DPRVKVIRLSRNFGQQAALLAGLD 77
Glyco_tranf_2_3 pfam13641
Glycosyltransferase like family 2; Members of this family of prokaryotic proteins include ...
 3-229 6.00e-03

Glycosyltransferase like family 2; Members of this family of prokaryotic proteins include putative glucosyltransferase, which are involved in bacterial capsule biosynthesis.


Pssm-ID: 433372 [Multi-domain]  Cd Length: 230  Bit Score: 38.12  E-value: 6.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938979348   3 DTGIVMPLYKQDiGYLQAAISSVLAQSYRAFRFIIVIDGAP-EMIEPALHAAMGDPRVQLVTLPQNQ-----GVSHALNR 76
Cdd:pfam13641   3 DVSVVVPAFNED-SVLGRVLEAILAQPYPPVEVVVVVNPSDaETLDVAEEIAARFPDVRLRVIRNARllgptGKSRGLNH 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938979348  77 GFdelfkdPAIK--YVTWVSSDNVYHSSFIERLrcelergpdslgLVFSTFRQIDAAGNPlydqQHQQALIRYQSQPH-- 152
Cdd:pfam13641  82 GF------RAVKsdLVVLHDDDSVLHPGTLKKY------------VQYFDSPKVGAVGTP----VFSLNRSTMLSALGal 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938979348 153 -------------HELLNASIVGVSFMYKSQYARLIDGYRLQPV--EDYDYWLRLTET-CNMKFIPEILMdyRVDSAFSV 216
Cdd:pfam13641 140 efalrhlrmmslrLALGVLPLSGAGSAIRREVLKELGLFDPFFLlgDDKSLGRRLRRHgWRVAYAPDAAV--RTVFPTYL 217

                         250
                  ....*....|...
gi 1938979348 217 SASLRsqkEHRRW 229
Cdd:pfam13641 218 AASIK---QRARW 227
Succinoglycan_BP_ExoA cd02525
ExoA is involved in the biosynthesis of succinoglycan; Succinoglycan Biosynthesis Protein ExoA ...
 6-119 6.68e-03

ExoA is involved in the biosynthesis of succinoglycan; Succinoglycan Biosynthesis Protein ExoA catalyzes the formation of a beta-1,3 linkage of the second sugar (glucose) of the succinoglycan with the galactose on the lipid carrie. Succinoglycan is an acidic exopolysaccharide that is important for invasion of the nodules. Succinoglycan is a high-molecular-weight polymer composed of repeating octasaccharide units. These units are synthesized on membrane-bound isoprenoid lipid carriers, beginning with galactose followed by seven glucose molecules, and modified by the addition of acetate, succinate, and pyruvate. ExoA is a membrane protein with a transmembrance domain at c-terminus.


Pssm-ID: 133016 [Multi-domain]  Cd Length: 249  Bit Score: 37.98  E-value: 6.68e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938979348   6 IVMPLYKQDiGYLQAAISSVLAQSYRAFRF-IIVIDG-----APEMIEpalHAAMGDPRVQLVTLPQnQGVSHALNRGFD 79
Cdd:cd02525     4 IIIPVRNEE-KYIEELLESLLNQSYPKDLIeIIVVDGgstdgTREIVQ---EYAAKDPRIRLIDNPK-RIQSAGLNIGIR 78

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1938979348  80 ELFKDpaikYVTWVSSDNVYHSSFIERL-RCELERGPDSLG 119
Cdd:cd02525    79 NSRGD----IIIRVDAHAVYPKDYILELvEALKRTGADNVG 115
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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