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Conserved domains on  [gi|1883737738|gb|QMT03000|]
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alpha/beta hydrolase [Gordonia jinghuaiqii]

Protein Classification

alpha/beta hydrolase( domain architecture ID 12114401)

alpha/beta hydrolase family protein catalyzes the hydrolysis of substrates with different chemical composition or physicochemical properties using a nucleophile-His-acid catalytic triad

CATH:  3.40.50.1820
EC:  3.-.-.-
Gene Ontology:  GO:0016787
PubMed:  12369917|19508187|37582413

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Hydrolase_4 pfam12146
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ...
 25-259 8.09e-84

Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.


:

Pssm-ID: 463473 [Multi-domain]  Cd Length: 238  Bit Score: 250.98  E-value: 8.09e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738  25 QAPRGVVVIAHGLAEHGRRYGYVAQRLVDAGYLVAIPDHVGHGRSGGKRMRLRRFGEFTADLDTVIAHVSDD--ALPTFL 102
Cdd:pfam12146   1 GEPRAVVVLVHGLGEHSGRYAHLADALAAQGFAVYAYDHRGHGRSDGKRGHVPSFDDYVDDLDTFVDKIREEhpGLPLFL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738 103 IGHSMGGCIALDYALDHQDVLDGLILSGAAVLPGDDLPALAIRF-AKVIGTVAPGLP-TTALSSSSISRDPAVVAEYDAD 180
Cdd:pfam12146  81 LGHSMGGLIAALYALRYPDKVDGLILSAPALKIKPYLAPPILKLlAKLLGKLFPRLRvPNNLLPDSLSRDPEVVAAYAAD 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1883737738 181 PLVTrGKIPAGLGGAMIATMQTFPARLPSLQLPILVMHGSEDALTDPKGSELVDRLADSTDKTLVIYDGLFHEIFNEPE 259
Cdd:pfam12146 161 PLVH-GGISARTLYELLDAGERLLRRAAAITVPLLLLHGGADRVVDPAGSREFYERAGSTDKTLKLYPGLYHELLNEPD 238
 
Name Accession Description Interval E-value
Hydrolase_4 pfam12146
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ...
 25-259 8.09e-84

Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.


Pssm-ID: 463473 [Multi-domain]  Cd Length: 238  Bit Score: 250.98  E-value: 8.09e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738  25 QAPRGVVVIAHGLAEHGRRYGYVAQRLVDAGYLVAIPDHVGHGRSGGKRMRLRRFGEFTADLDTVIAHVSDD--ALPTFL 102
Cdd:pfam12146   1 GEPRAVVVLVHGLGEHSGRYAHLADALAAQGFAVYAYDHRGHGRSDGKRGHVPSFDDYVDDLDTFVDKIREEhpGLPLFL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738 103 IGHSMGGCIALDYALDHQDVLDGLILSGAAVLPGDDLPALAIRF-AKVIGTVAPGLP-TTALSSSSISRDPAVVAEYDAD 180
Cdd:pfam12146  81 LGHSMGGLIAALYALRYPDKVDGLILSAPALKIKPYLAPPILKLlAKLLGKLFPRLRvPNNLLPDSLSRDPEVVAAYAAD 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1883737738 181 PLVTrGKIPAGLGGAMIATMQTFPARLPSLQLPILVMHGSEDALTDPKGSELVDRLADSTDKTLVIYDGLFHEIFNEPE 259
Cdd:pfam12146 161 PLVH-GGISARTLYELLDAGERLLRRAAAITVPLLLLHGGADRVVDPAGSREFYERAGSTDKTLKLYPGLYHELLNEPD 238
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
1-273 2.54e-59

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 188.29  E-value: 2.54e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738   1 MTPEEHSFRGTHGHTIVYDVFRPEQAPRGVVVIAHGLAEHGRRYGYVAQRLVDAGYLVAIPDHVGHGRSGGKRMRLRRFG 80
Cdd:COG2267     1 MTRRLVTLPTRDGLRLRGRRWRPAGSPRGTVVLVHGLGEHSGRYAELAEALAAAGYAVLAFDLRGHGRSDGPRGHVDSFD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738  81 EFTADLDTVIAHV-SDDALPTFLIGHSMGGCIALDYALDHQDVLDGLILSGAAvlpgddlpalairfakvigtvapglpt 159
Cdd:COG2267    81 DYVDDLRAALDALrARPGLPVVLLGHSMGGLIALLYAARYPDRVAGLVLLAPA--------------------------- 133

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738 160 talssssisrdpavvaeYDADPLVTrgkIPAGLGGAMiatmqTFPARLPSLQLPILVMHGSEDALTDPKGSE-LVDRLad 238
Cdd:COG2267   134 -----------------YRADPLLG---PSARWLRAL-----RLAEALARIDVPVLVLHGGADRVVPPEAARrLAARL-- 186

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 1883737738 239 STDKTLVIYDGLFHEIFNEPERDVVLDEVVEWLGA 273
Cdd:COG2267   187 SPDVELVLLPGARHELLNEPAREEVLAAILAWLER 221
PHA02857 PHA02857
monoglyceride lipase; Provisional
 6-271 4.27e-43

monoglyceride lipase; Provisional


Pssm-ID: 165193 [Multi-domain]  Cd Length: 276  Bit Score: 148.11  E-value: 4.27e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738   6 HSFRGTHGHTIVYDVFRPEQAPRGVVVIAHGLAEHGRRYGYVAQRLVDAGYLVAIPDHVGHGRSGGKRMRLRRFGEFTAD 85
Cdd:PHA02857    3 NCMFNLDNDYIYCKYWKPITYPKALVFISHGAGEHSGRYEELAENISSLGILVFSHDHIGHGRSNGEKMMIDDFGVYVRD 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738  86 ldtVIAHV-----SDDALPTFLIGHSMGGCIALDYALDHQDVLDGLILSgAAVLPGDDLPALAIRFAKVIGTVAPGLPTT 160
Cdd:PHA02857   83 ---VVQHVvtiksTYPGVPVFLLGHSMGATISILAAYKNPNLFTAMILM-SPLVNAEAVPRLNLLAAKLMGIFYPNKIVG 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738 161 ALSSSSISRDPAVVAEYDADPLVTRGKIPAGLGGAMIATMQTFPARLPSLQLPILVMHGSEDALTDPKGSELVDRLADSt 240
Cdd:PHA02857  159 KLCPESVSRDMDEVYKYQYDPLVNHEKIKAGFASQVLKATNKVRKIIPKIKTPILILQGTNNEISDVSGAYYFMQHANC- 237

                         250       260       270
                  ....*....|....*....|....*....|...
gi 1883737738 241 DKTLVIYDGLFHEIFNEPE--RDVVLDEVVEWL 271
Cdd:PHA02857  238 NREIKIYEGAKHHLHKETDevKKSVMKEIETWI 270
PST-A TIGR01607
Plasmodium subtelomeric family (PST-A); This model represents a paralogous family of genes in ...
 29-271 2.03e-08

Plasmodium subtelomeric family (PST-A); This model represents a paralogous family of genes in Plasmodium falciparum and Plasmodium yoelii, which are closely related to various phospholipases and lysophospholipases of plants as well as generally being related to the alpha/beta-fold superfamily of hydrolases. These genes are preferentially located in the subtelomeric regions of the chromosomes of both P. falciparum and P. yoelii.


Pssm-ID: 162444 [Multi-domain]  Cd Length: 332  Bit Score: 54.40  E-value: 2.03e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738  29 GVVVIAHGLAEHGRrYGYVAQR----------LVDA-----------------GYLVAIPDHVGHGRSGGK---RMRLRR 78
Cdd:TIGR01607  22 GIIVLIHGLKSHLR-LQFLKINakivnndravLIDTdnyyiykdswienfnknGYSVYGLDLQGHGESDGLqnlRGHINC 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738  79 FGEFTADLDTVIAHVSDDA----------------------LPTFLIGHSMGGCIAL---DYALDHQDVLDGLILSGAAV 133
Cdd:TIGR01607 101 FDDLVYDVIQYMNRINDSIilenetksddesydivntkenrLPMYIIGLSMGGNIALrllELLGKSNENNDKLNIKGCIS 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738 134 LPG---------DDLPALAIRFAKVIGTVAPGLPTTALSSS-SISRDPAVVAEYDADPLVTRGKIPAGLGGAMIATMQTF 203
Cdd:TIGR01607 181 LSGmisiksvgsDDSFKFKYFYLPVMNFMSRVFPTFRISKKiRYEKSPYVNDIIKFDKFRYDGGITFNLASELIKATDTL 260

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1883737738 204 PA---RLPSlQLPILVMHGSEDALTDPKGSELVDRLADSTDKTLVIYDGLFHEIFNEPERDVVLDEVVEWL 271
Cdd:TIGR01607 261 DCdidYIPK-DIPILFIHSKGDCVCSYEGTVSFYNKLSISNKELHTLEDMDHVITIEPGNEEVLKKIIEWI 330
 
Name Accession Description Interval E-value
Hydrolase_4 pfam12146
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ...
 25-259 8.09e-84

Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.


Pssm-ID: 463473 [Multi-domain]  Cd Length: 238  Bit Score: 250.98  E-value: 8.09e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738  25 QAPRGVVVIAHGLAEHGRRYGYVAQRLVDAGYLVAIPDHVGHGRSGGKRMRLRRFGEFTADLDTVIAHVSDD--ALPTFL 102
Cdd:pfam12146   1 GEPRAVVVLVHGLGEHSGRYAHLADALAAQGFAVYAYDHRGHGRSDGKRGHVPSFDDYVDDLDTFVDKIREEhpGLPLFL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738 103 IGHSMGGCIALDYALDHQDVLDGLILSGAAVLPGDDLPALAIRF-AKVIGTVAPGLP-TTALSSSSISRDPAVVAEYDAD 180
Cdd:pfam12146  81 LGHSMGGLIAALYALRYPDKVDGLILSAPALKIKPYLAPPILKLlAKLLGKLFPRLRvPNNLLPDSLSRDPEVVAAYAAD 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1883737738 181 PLVTrGKIPAGLGGAMIATMQTFPARLPSLQLPILVMHGSEDALTDPKGSELVDRLADSTDKTLVIYDGLFHEIFNEPE 259
Cdd:pfam12146 161 PLVH-GGISARTLYELLDAGERLLRRAAAITVPLLLLHGGADRVVDPAGSREFYERAGSTDKTLKLYPGLYHELLNEPD 238
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
1-273 2.54e-59

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 188.29  E-value: 2.54e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738   1 MTPEEHSFRGTHGHTIVYDVFRPEQAPRGVVVIAHGLAEHGRRYGYVAQRLVDAGYLVAIPDHVGHGRSGGKRMRLRRFG 80
Cdd:COG2267     1 MTRRLVTLPTRDGLRLRGRRWRPAGSPRGTVVLVHGLGEHSGRYAELAEALAAAGYAVLAFDLRGHGRSDGPRGHVDSFD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738  81 EFTADLDTVIAHV-SDDALPTFLIGHSMGGCIALDYALDHQDVLDGLILSGAAvlpgddlpalairfakvigtvapglpt 159
Cdd:COG2267    81 DYVDDLRAALDALrARPGLPVVLLGHSMGGLIALLYAARYPDRVAGLVLLAPA--------------------------- 133

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738 160 talssssisrdpavvaeYDADPLVTrgkIPAGLGGAMiatmqTFPARLPSLQLPILVMHGSEDALTDPKGSE-LVDRLad 238
Cdd:COG2267   134 -----------------YRADPLLG---PSARWLRAL-----RLAEALARIDVPVLVLHGGADRVVPPEAARrLAARL-- 186

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 1883737738 239 STDKTLVIYDGLFHEIFNEPERDVVLDEVVEWLGA 273
Cdd:COG2267   187 SPDVELVLLPGARHELLNEPAREEVLAAILAWLER 221
PHA02857 PHA02857
monoglyceride lipase; Provisional
 6-271 4.27e-43

monoglyceride lipase; Provisional


Pssm-ID: 165193 [Multi-domain]  Cd Length: 276  Bit Score: 148.11  E-value: 4.27e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738   6 HSFRGTHGHTIVYDVFRPEQAPRGVVVIAHGLAEHGRRYGYVAQRLVDAGYLVAIPDHVGHGRSGGKRMRLRRFGEFTAD 85
Cdd:PHA02857    3 NCMFNLDNDYIYCKYWKPITYPKALVFISHGAGEHSGRYEELAENISSLGILVFSHDHIGHGRSNGEKMMIDDFGVYVRD 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738  86 ldtVIAHV-----SDDALPTFLIGHSMGGCIALDYALDHQDVLDGLILSgAAVLPGDDLPALAIRFAKVIGTVAPGLPTT 160
Cdd:PHA02857   83 ---VVQHVvtiksTYPGVPVFLLGHSMGATISILAAYKNPNLFTAMILM-SPLVNAEAVPRLNLLAAKLMGIFYPNKIVG 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738 161 ALSSSSISRDPAVVAEYDADPLVTRGKIPAGLGGAMIATMQTFPARLPSLQLPILVMHGSEDALTDPKGSELVDRLADSt 240
Cdd:PHA02857  159 KLCPESVSRDMDEVYKYQYDPLVNHEKIKAGFASQVLKATNKVRKIIPKIKTPILILQGTNNEISDVSGAYYFMQHANC- 237

                         250       260       270
                  ....*....|....*....|....*....|...
gi 1883737738 241 DKTLVIYDGLFHEIFNEPE--RDVVLDEVVEWL 271
Cdd:PHA02857  238 NREIKIYEGAKHHLHKETDevKKSVMKEIETWI 270
PLN02652 PLN02652
hydrolase; alpha/beta fold family protein
 8-271 1.03e-31

hydrolase; alpha/beta fold family protein


Pssm-ID: 215352 [Multi-domain]  Cd Length: 395  Bit Score: 121.15  E-value: 1.03e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738   8 FRGTHGHTIVYDVFRPEQAP-RGVVVIAHGLAEHGRRYGYVAQRLVDAGYLVAIPDHVGHGRSGGKRMRLRRFGEFTADL 86
Cdd:PLN02652  115 FYGARRNALFCRSWAPAAGEmRGILIIIHGLNEHSGRYLHFAKQLTSCGFGVYAMDWIGHGGSDGLHGYVPSLDYVVEDT 194

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738  87 DTVIAHV--SDDALPTFLIGHSMGGCIALDYAL--DHQDVLDGLILSGaavlpgddlPALAIRFAK-VIGTVAP------ 155
Cdd:PLN02652  195 EAFLEKIrsENPGVPCFLFGHSTGGAVVLKAASypSIEDKLEGIVLTS---------PALRVKPAHpIVGAVAPifslva 265

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738 156 -----------GLPttalssssISRDPAVVAEYDADPLVTRGKIPAGLGGAMIATMQTFPARLPSLQLPILVMHGSEDAL 224
Cdd:PLN02652  266 prfqfkgankrGIP--------VSRDPAALLAKYSDPLVYTGPIRVRTGHEILRISSYLTRNFKSVTVPFMVLHGTADRV 337

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 1883737738 225 TDPKGSELVDRLADSTDKTLVIYDGLFHEIFNEPERDVVLDEVVEWL 271
Cdd:PLN02652  338 TDPLASQDLYNEAASRHKDIKLYDGFLHDLLFEPEREEVGRDIIDWM 384
YvaK COG1647
Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];
21-276 6.42e-27

Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 441253 [Multi-domain]  Cd Length: 246  Bit Score: 105.02  E-value: 6.42e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738  21 FRPEQAPRGVVVIaHGLAEHGRRYGYVAQRLVDAGYLVAIPDHVGHGRSGGKrMRLRRFGEFTADLDTVIAHVSDDALPT 100
Cdd:COG1647     9 FFLEGGRKGVLLL-HGFTGSPAEMRPLAEALAKAGYTVYAPRLPGHGTSPED-LLKTTWEDWLEDVEEAYEILKAGYDKV 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738 101 FLIGHSMGGCIALDYALDHQDVlDGLILSGAAVLPgDDLPALAIRFAKVIGtvapglPTTALSSSSISRDPAVVAEYDAD 180
Cdd:COG1647    87 IVIGLSMGGLLALLLAARYPDV-AGLVLLSPALKI-DDPSAPLLPLLKYLA------RSLRGIGSDIEDPEVAEYAYDRT 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738 181 PLvtrgkipaglggAMIATMQTF----PARLPSLQLPILVMHGSEDALTDPKGSELVDRLADSTDKTLVIYDGLFHEIFN 256
Cdd:COG1647   159 PL------------RALAELQRLirevRRDLPKITAPTLIIQSRKDEVVPPESARYIYERLGSPDKELVWLEDSGHVITL 226

                         250       260
                  ....*....|....*....|
gi 1883737738 257 EPERDVVLDEVVEWLGAHTP 276
Cdd:COG1647   227 DKDREEVAEEILDFLERLAA 246
PLN02385 PLN02385
hydrolase; alpha/beta fold family protein
 23-274 4.31e-25

hydrolase; alpha/beta fold family protein


Pssm-ID: 215216 [Multi-domain]  Cd Length: 349  Bit Score: 102.14  E-value: 4.31e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738  23 PEQAPRGVVVIAHGlaehgrrYGY--------VAQRLVDAGYLVAIPDHVGHGRSGGKRMRLRRFGEFtadLDTVIAHVS 94
Cdd:PLN02385   82 ENSRPKAAVCFCHG-------YGDtctfffegIARKIASSGYGVFAMDYPGFGLSEGLHGYIPSFDDL---VDDVIEHYS 151

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738  95 D-------DALPTFLIGHSMGGCIALDYALDHQDVLDGLILSGAAVLPGDDL--PALAIRFAKVIGTVAPG---LPTTAL 162
Cdd:PLN02385  152 KikgnpefRGLPSFLFGQSMGGAVALKVHLKQPNAWDGAILVAPMCKIADDVvpPPLVLQILILLANLLPKaklVPQKDL 231

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738 163 SSSSIsRDPAV--VAEYDADPLVTRGKIPAGLggAMIATMQTFPARLPSLQLPILVMHGSEDALTDPKGSELVDRLADST 240
Cdd:PLN02385  232 AELAF-RDLKKrkMAEYNVIAYKDKPRLRTAV--ELLRTTQEIEMQLEEVSLPLLILHGEADKVTDPSVSKFLYEKASSS 308

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 1883737738 241 DKTLVIYDGLFHEIFN-EPERDV--VLDEVVEWLGAH 274
Cdd:PLN02385  309 DKKLKLYEDAYHSILEgEPDEMIfqVLDDIISWLDSH 345
PLN02298 PLN02298
hydrolase, alpha/beta fold family protein
 22-271 5.79e-24

hydrolase, alpha/beta fold family protein


Pssm-ID: 165939 [Multi-domain]  Cd Length: 330  Bit Score: 98.70  E-value: 5.79e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738  22 RPEQAPRGVVVIAHGlaeHGRRYGYVAQR----LVDAGYLVAIPDHVGHGRSGGKRMRLRRFGEFTADL----DTVIAHV 93
Cdd:PLN02298   53 SSSSPPRALIFMVHG---YGNDISWTFQStaifLAQMGFACFALDLEGHGRSEGLRAYVPNVDLVVEDClsffNSVKQRE 129

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738  94 SDDALPTFLIGHSMGGCIALDYALDHQDVLDGLILSGAAVLPGDD------LPALAIRFAKVIGTvAPGLPTTALSSSSI 167
Cdd:PLN02298  130 EFQGLPRFLYGESMGGAICLLIHLANPEGFDGAVLVAPMCKISDKirppwpIPQILTFVARFLPT-LAIVPTADLLEKSV 208

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738 168 sRDPAVVAEYDADPLVTRGKIPAGLGGAMIATMQTFPARLPSLQLPILVMHGSEDALTDPKGSELVDRLADSTDKTLVIY 247
Cdd:PLN02298  209 -KVPAKKIIAKRNPMRYNGKPRLGTVVELLRVTDYLGKKLKDVSIPFIVLHGSADVVTDPDVSRALYEEAKSEDKTIKIY 287

                         250       260
                  ....*....|....*....|....*..
gi 1883737738 248 DGLFHE-IFNEPERDV--VLDEVVEWL 271
Cdd:PLN02298  288 DGMMHSlLFGEPDENIeiVRRDILSWL 314
FrsA COG1073
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms]; ...
 4-274 3.92e-22

Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms];


Pssm-ID: 440691 [Multi-domain]  Cd Length: 253  Bit Score: 92.29  E-value: 3.92e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738   4 EEHSFRGTHGHTIVYDVFRP--EQAPRGVVVIAHGLAEHGRRYGYVAQRLVDAGYLVAIPDHVGHGRSGGKRmrlRRFGE 81
Cdd:COG1073    11 EDVTFKSRDGIKLAGDLYLPagASKKYPAVVVAHGNGGVKEQRALYAQRLAELGFNVLAFDYRGYGESEGEP---REEGS 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738  82 FTA-DLDTVIAHVSD----DALPTFLIGHSMGGCIALDYALDHQDVlDGLILSGaavlPGDDLPALAI-RFAKVIGTVAP 155
Cdd:COG1073    88 PERrDARAAVDYLRTlpgvDPERIGLLGISLGGGYALNAAATDPRV-KAVILDS----PFTSLEDLAAqRAKEARGAYLP 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738 156 GLP-TTALSSSSISRDpavvaeyDADPLvtrgkipaglggamiatmqtfpARLPSLQLPILVMHGSEDALTDPKGSELVD 234
Cdd:COG1073   163 GVPyLPNVRLASLLND-------EFDPL----------------------AKIEKISRPLLFIHGEKDEAVPFYMSEDLY 213

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 1883737738 235 RLAdSTDKTLVIYDGLFHEIFNEPERDVVLDEVVEWLGAH 274
Cdd:COG1073   214 EAA-AEPKELLIVPGAGHVDLYDRPEEEYFDKLAEFFKKN 252
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 11-274 5.96e-22

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 91.22  E-value: 5.96e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738  11 THGHTIVYDVFRPEQAPrgvVVIAHGLAEHGRRYGYVAQRLvDAGYLVAIPDHVGHGRSGgKRMRLRRFGEFTADLDTVI 90
Cdd:COG0596     9 VDGVRLHYREAGPDGPP---VVLLHGLPGSSYEWRPLIPAL-AAGYRVIAPDLRGHGRSD-KPAGGYTLDDLADDLAALL 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738  91 AHVSDDalPTFLIGHSMGGCIALDYALDHQDVLDGLILSGAAVlpgddlpalairfakvigtvapglpttalssssisrd 170
Cdd:COG0596    84 DALGLE--RVVLVGHSMGGMVALELAARHPERVAGLVLVDEVL------------------------------------- 124

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738 171 pavvaEYDADPLVTRGKIPAGLGGAMIATMQT-FPARLPSLQLPILVMHGSEDALTDPKGSE-LVDRLADStdkTLVIYD 248
Cdd:COG0596   125 -----AALAEPLRRPGLAPEALAALLRALARTdLRERLARITVPTLVIWGEKDPIVPPALARrLAELLPNA---ELVVLP 196

                         250       260
                  ....*....|....*....|....*.
gi 1883737738 249 GLFHEIFNEpERDVVLDEVVEWLGAH 274
Cdd:COG0596   197 GAGHFPPLE-QPEAFAAALRDFLARL 221
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
7-274 1.35e-19

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 85.07  E-value: 1.35e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738   7 SFRGTHGHTIVYDVFRPEQA-PRGVVVIAHGL-AEHGRRYGYVAQRLVDAGYLVAIPDHVGHGRSGGKrmrlrRFGEFTA 84
Cdd:COG1506     1 TFKSADGTTLPGWLYLPADGkKYPVVVYVHGGpGSRDDSFLPLAQALASRGYAVLAPDYRGYGESAGD-----WGGDEVD 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738  85 DLDTVIAHVSD----DALPTFLIGHSMGGCIALDYALDHQDVLDGLIlSGAAVLPGDDLPALAIRFAKVIGtvapGLPtt 160
Cdd:COG1506    76 DVLAAIDYLAArpyvDPDRIGIYGHSYGGYMALLAAARHPDRFKAAV-ALAGVSDLRSYYGTTREYTERLM----GGP-- 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738 161 alssssiSRDPAVVAEYdaDPLvtrgkipaglggamiatmqtfpARLPSLQLPILVMHGSEDALTDPKGSE-LVDRLAD- 238
Cdd:COG1506   149 -------WEDPEAYAAR--SPL----------------------AYADKLKTPLLLIHGEADDRVPPEQAErLYEALKKa 197

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 1883737738 239 STDKTLVIYDGLFHEIFNEPERDvVLDEVVEWLGAH 274
Cdd:COG1506   198 GKPVELLVYPGEGHGFSGAGAPD-YLERILDFLDRH 232
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 29-255 4.63e-17

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 78.32  E-value: 4.63e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738  29 GVVVIAHGLAEHGRRYGYVAQRLVDAGYLVAIPDHVGHGRSGgKRMRLRRFGEFT--ADLDTVIAHVSDDalPTFLIGHS 106
Cdd:pfam00561   1 PPVLLLHGLPGSSDLWRKLAPALARDGFRVIALDLRGFGKSS-RPKAQDDYRTDDlaEDLEYILEALGLE--KVNLVGHS 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738 107 MGGCIALDYALDHQDVLDGLILSGA---AVLPGDDLPALAIRFAKVI-GTVAPGLPTTALSSSSI--------SRDPAVV 174
Cdd:pfam00561  78 MGGLIALAYAAKYPDRVKALVLLGAldpPHELDEADRFILALFPGFFdGFVADFAPNPLGRLVAKllallllrLRLLKAL 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738 175 AEYDADPLVTRGKIPAGLGGAMIATMQTFPAR-----LPSLQLPILVMHGSEDALTDPKGSELVDRLadSTDKTLVIYDG 249
Cdd:pfam00561 158 PLLNKRFPSGDYALAKSLVTGALLFIETWSTElrakfLGRLDEPTLIIWGDQDPLVPPQALEKLAQL--FPNARLVVIPD 235


                  ....*.
gi 1883737738 250 LFHEIF 255
Cdd:pfam00561 236 AGHFAF 241
DLH COG0412
Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];
1-262 2.78e-14

Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440181 [Multi-domain]  Cd Length: 226  Bit Score: 70.38  E-value: 2.78e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738   1 MTPEEHSFRGTHGHTIVYDVFRPE-QAPRGVVVIAH---GLAEHGRRygyVAQRLVDAGYLVAIPDHVGHGRSGG----- 71
Cdd:COG0412     1 MTTETVTIPTPDGVTLPGYLARPAgGGPRPGVVVLHeifGLNPHIRD---VARRLAAAGYVVLAPDLYGRGGPGDdpdea 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738  72 -KRMRLRRFGEFTADLDTVIAHVSD----DALPTFLIGHSMGGCIALDYALDHQDVldglilsGAAVlpgddlpalairf 146
Cdd:COG0412    78 rALMGALDPELLAADLRAALDWLKAqpevDAGRVGVVGFCFGGGLALLAAARGPDL-------AAAV------------- 137

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738 147 akvigTVAPGLPTTALssssisrdpavvaeydadplvtrgkipaglggamiatmqtfPARLPSLQLPILVMHGSEDALTD 226
Cdd:COG0412   138 -----SFYGGLPADDL-----------------------------------------LDLAARIKAPVLLLYGEKDPLVP 171

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 1883737738 227 PKGSE-LVDRLADS-TDKTLVIYDGLFHEiFNEPERDV 262
Cdd:COG0412   172 PEQVAaLEAALAAAgVDVELHVYPGAGHG-FTNPGRPR 208
COG4188 COG4188
Predicted dienelactone hydrolase [General function prediction only];
23-258 7.09e-14

Predicted dienelactone hydrolase [General function prediction only];


Pssm-ID: 443342 [Multi-domain]  Cd Length: 326  Bit Score: 70.52  E-value: 7.09e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738  23 PEQAPRGVVVIAHGLAEHGRRYGYVAQRLVDAGYLVAIPDHVGHGRSGGKRMRLRRFGEFTA--------DLDTVIAHV- 93
Cdd:COG4188    57 PAGGPFPLVVLSHGLGGSREGYAYLAEHLASHGYVVAAPDHPGSNAADLSAALDGLADALDPeelwerplDLSFVLDQLl 136

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738  94 -SDDALPTF----------LIGHSMGGCIAldyaldhqdvldgLILSGAAVlpgdDLPALAIRFAKVIGTVAPGLPTTAL 162
Cdd:COG4188   137 aLNKSDPPLagrldldrigVIGHSLGGYTA-------------LALAGARL----DFAALRQYCGKNPDLQCRALDLPRL 199

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738 163 SSSsiSRDP---AVVAeydADPLVTRGKIPAGLGGamiatmqtfparlpsLQLPILVMHGSEDALTD-PKGSELVDRLAD 238
Cdd:COG4188   200 AYD--LRDPrikAVVA---LAPGGSGLFGEEGLAA---------------ITIPVLLVAGSADDVTPaPDEQIRPFDLLP 259

                         250       260
                  ....*....|....*....|
gi 1883737738 239 STDKTLVIYDGLFHEIFNEP 258
Cdd:COG4188   260 GADKYLLTLEGATHFSFLDP 279
YheT COG0429
Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only];
1-133 3.21e-12

Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only];


Pssm-ID: 440198 [Multi-domain]  Cd Length: 323  Bit Score: 65.55  E-value: 3.21e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738   1 MTPEEHSFRGTHGHTIVYDVFRPEQAPRGVVVIAHGLAEHGRRyGYV---AQRLVDAGYLVAIPDHVGHgrsGGKRMRLR 77
Cdd:COG0429    34 LPYRRERLELPDGDFVDLDWSDPPAPSKPLVVLLHGLEGSSDS-HYArglARALYARGWDVVRLNFRGC---GGEPNLLP 109

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1883737738  78 RF---GEfTADLDTVIAHV--SDDALPTFLIGHSMGGCIALDYALDHQDvlDGLILSGAAV 133
Cdd:COG0429   110 RLyhsGD-TEDLVWVLAHLraRYPYAPLYAVGFSLGGNLLLKYLGEQGD--DAPPLKAAVA 167
PRK10749 PRK10749
lysophospholipase L2; Provisional
 4-128 8.24e-09

lysophospholipase L2; Provisional


Pssm-ID: 182697  Cd Length: 330  Bit Score: 55.39  E-value: 8.24e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738   4 EEHSFRGTHGHTIVYDVFRPEQAPRgVVVIAHGLAEHGRRYGYVAQRLVDAGYLVAIPDHVGHGRSG-----GKRMRLRR 78
Cdd:PRK10749   31 EEAEFTGVDDIPIRFVRFRAPHHDR-VVVICPGRIESYVKYAELAYDLFHLGYDVLIIDHRGQGRSGrllddPHRGHVER 109

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1883737738  79 FGEFTADLDTVIAHvsdDALPT-----FLIGHSMGGCIALDYALDHQDVLDGLIL 128
Cdd:PRK10749  110 FNDYVDDLAAFWQQ---EIQPGpyrkrYALAHSMGGAILTLFLQRHPGVFDAIAL 161
PST-A TIGR01607
Plasmodium subtelomeric family (PST-A); This model represents a paralogous family of genes in ...
 29-271 2.03e-08

Plasmodium subtelomeric family (PST-A); This model represents a paralogous family of genes in Plasmodium falciparum and Plasmodium yoelii, which are closely related to various phospholipases and lysophospholipases of plants as well as generally being related to the alpha/beta-fold superfamily of hydrolases. These genes are preferentially located in the subtelomeric regions of the chromosomes of both P. falciparum and P. yoelii.


Pssm-ID: 162444 [Multi-domain]  Cd Length: 332  Bit Score: 54.40  E-value: 2.03e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738  29 GVVVIAHGLAEHGRrYGYVAQR----------LVDA-----------------GYLVAIPDHVGHGRSGGK---RMRLRR 78
Cdd:TIGR01607  22 GIIVLIHGLKSHLR-LQFLKINakivnndravLIDTdnyyiykdswienfnknGYSVYGLDLQGHGESDGLqnlRGHINC 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738  79 FGEFTADLDTVIAHVSDDA----------------------LPTFLIGHSMGGCIAL---DYALDHQDVLDGLILSGAAV 133
Cdd:TIGR01607 101 FDDLVYDVIQYMNRINDSIilenetksddesydivntkenrLPMYIIGLSMGGNIALrllELLGKSNENNDKLNIKGCIS 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738 134 LPG---------DDLPALAIRFAKVIGTVAPGLPTTALSSS-SISRDPAVVAEYDADPLVTRGKIPAGLGGAMIATMQTF 203
Cdd:TIGR01607 181 LSGmisiksvgsDDSFKFKYFYLPVMNFMSRVFPTFRISKKiRYEKSPYVNDIIKFDKFRYDGGITFNLASELIKATDTL 260

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1883737738 204 PA---RLPSlQLPILVMHGSEDALTDPKGSELVDRLADSTDKTLVIYDGLFHEIFNEPERDVVLDEVVEWL 271
Cdd:TIGR01607 261 DCdidYIPK-DIPILFIHSKGDCVCSYEGTVSFYNKLSISNKELHTLEDMDHVITIEPGNEEVLKKIIEWI 330
Abhydrolase_6 pfam12697
Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse ...
 31-260 7.16e-08

Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse specificity.


Pssm-ID: 463673 [Multi-domain]  Cd Length: 211  Bit Score: 51.71  E-value: 7.16e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738  31 VVIAHGLAEHGRRYgyvaQRLVDAGYLVAIPDHVGHGRSGGKRMRLRRFGEFTADLDTVIAhvsddALPTFLIGHSMGGC 110
Cdd:pfam12697   1 VVLVHGAGLSAAPL----AALLAAGVAVLAPDLPGHGSSSPPPLDLADLADLAALLDELGA-----ARPVVLVGHSLGGA 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738 111 IALDYAldHQDVLDGLILSGAAVLPGDDLPALAIRFAKVIGTVAPGLPTTALSSSSISRDPAVVAEYDAdplvtrgkIPA 190
Cdd:pfam12697  72 VALAAA--AAALVVGVLVAPLAAPPGLLAALLALLARLGAALAAPAWLAAESLARGFLDDLPADAEWAA--------ALA 141

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738 191 GLGGAMIATMQTFPARLPSLQLPILVMHGSEDALTDpkgsELVDRLADSTDKTLVIYDGLFHEIFNEPER 260
Cdd:pfam12697 142 RLAALLAALALLPLAAWRDLPVPVLVLAEEDRLVPE----LAQRLLAALAGARLVVLPGAGHLPLDDPEE 207
YpfH COG0400
Predicted esterase [General function prediction only];
24-149 1.01e-06

Predicted esterase [General function prediction only];


Pssm-ID: 440169 [Multi-domain]  Cd Length: 200  Bit Score: 48.36  E-value: 1.01e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738  24 EQAPRGVVVIAHGLAEHGRRYGYVAQRLVDAGYLVAIPD----HVGHGRS------GGKRMRLRRFGEFTADLDTVIAHV 93
Cdd:COG0400     1 GGPAAPLVVLLHGYGGDEEDLLPLAPELALPGAAVLAPRapvpEGPGGRAwfdlsfLEGREDEEGLAAAAEALAAFIDEL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738  94 SD----DALPTFLIGHSMGGCIALDYALDHQDVLDGLILSGAAVLPGDDLPALAIRFAKV 149
Cdd:COG0400    81 EArygiDPERIVLAGFSQGAAMALSLALRRPELLAGVVALSGYLPGEEALPAPEAALAGT 140
EstA COG1075
Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and ...
 25-127 4.58e-06

Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and metabolism];


Pssm-ID: 440693 [Multi-domain]  Cd Length: 106  Bit Score: 44.44  E-value: 4.58e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738  25 QAPRGVVVIAHGLAEHGRRYGYVAQRLVDAGYLVAIPDHvgHGRSGGKRMRLRRFGEFtadLDTVIAHvsDDALPTFLIG 104
Cdd:COG1075     2 AATRYPVVLVHGLGGSAASWAPLAPRLRAAGYPVYALNY--PSTNGSIEDSAEQLAAF---VDAVLAA--TGAEKVDLVG 74

                          90       100
                  ....*....|....*....|....*
gi 1883737738 105 HSMGGCIALDYA--LDHQDVLDGLI 127
Cdd:COG1075    75 HSMGGLVARYYLkrLGGAAKVARVV 99
DLH pfam01738
Dienelactone hydrolase family;
20-116 1.63e-04

Dienelactone hydrolase family;


Pssm-ID: 396343 [Multi-domain]  Cd Length: 213  Bit Score: 41.95  E-value: 1.63e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738  20 VFRPEQAPRGVVVIAH---GLAEHGRRygyVAQRLVDAGYLVAIPD-HVGHGRSG---------GKRMRLRRFGEFTADL 86
Cdd:pfam01738   4 LATPKNPPWPVVVVFQeifGVNDNIRE---IADRLADEGYVALAPDlYFRQGDPNdeadaaramFELVSKRVMEKVLDDL 80

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1883737738  87 DTVIAHVSddALPTF------LIGHSMGGCIALDYA 116
Cdd:pfam01738  81 EAAVNYLK--SQPEVspkkvgVVGYCMGGALAVLLA 114
PRK11126 PRK11126
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase; Provisional
 31-131 1.65e-04

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase; Provisional


Pssm-ID: 236855 [Multi-domain]  Cd Length: 242  Bit Score: 42.13  E-value: 1.65e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738  31 VVIAHGLAEHGRRYGYVAQRLvdAGYLVAIPDHVGHGRSggKRMRLRRFGEFTADLDTVIAHVSDdaLPTFLIGHSMGGC 110
Cdd:PRK11126    5 LVFLHGLLGSGQDWQPVGEAL--PDYPRLYIDLPGHGGS--AAISVDGFADVSRLLSQTLQSYNI--LPYWLVGYSLGGR 78

                          90       100
                  ....*....|....*....|..
gi 1883737738 111 IALDYALDHQ-DVLDGLILSGA 131
Cdd:PRK11126   79 IAMYYACQGLaGGLCGLIVEGG 100
pro_imino_pep_2 TIGR01250
proline-specific peptidase, Bacillus coagulans-type subfamily; This model describes a ...
 82-130 5.53e-04

proline-specific peptidase, Bacillus coagulans-type subfamily; This model describes a subfamily of the alpha/beta fold family of hydrolases. Characterized members include prolinases (Pro-Xaa dipeptidase, EC 3.4.13.8), prolyl aminopeptidases (EC 3.4.11.5), and a leucyl aminopeptidase


Pssm-ID: 188121 [Multi-domain]  Cd Length: 289  Bit Score: 40.83  E-value: 5.53e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1883737738  82 FTADLDTVIAHVSDDALptFLIGHSMGGCIALDYALDHQDVLDGLILSG 130
Cdd:TIGR01250  83 FVDELEEVREKLGLDKF--YLLGHSWGGMLAQEYALKYGQHLKGLIISS 129
Aes COG0657
Acetyl esterase/lipase [Lipid transport and metabolism];
19-274 1.48e-03

Acetyl esterase/lipase [Lipid transport and metabolism];


Pssm-ID: 440422 [Multi-domain]  Cd Length: 207  Bit Score: 38.70  E-value: 1.48e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738  19 DVFRPE--QAPRGVVVIAHG---LAEHGRRYGYVAQRLVD-AGYLVAIPDHvghgrsggkrmRL---RRFGEFTADLDTV 89
Cdd:COG0657     2 DVYRPAgaKGPLPVVVYFHGggwVSGSKDTHDPLARRLAArAGAAVVSVDY-----------RLapeHPFPAALEDAYAA 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738  90 IAHVSD-------DALPTFLIGHSMGGCIALDYALDHQDvldglilsgaavlPGDDLPALAIRFAkvigtvapglPTTAL 162
Cdd:COG0657    71 LRWLRAnaaelgiDPDRIAVAGDSAGGHLAAALALRARD-------------RGGPRPAAQVLIY----------PVLDL 127

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738 163 SSSSISRDpavvaeydadplvtrgkipaglggamiatmqtfPARLPslqlPILVMHGSEDALTDPkGSELVDRLADS-TD 241
Cdd:COG0657   128 TASPLRAD---------------------------------LAGLP----PTLIVTGEADPLVDE-SEALAAALRAAgVP 169

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 1883737738 242 KTLVIYDGLFHEIFN---EPERDVVLDEVVEWLGAH 274
Cdd:COG0657   170 VELHVYPGGGHGFGLlagLPEARAALAEIAAFLRRA 205
Abhydrolase_11 pfam20408
Alpha/beta hydrolase domain; This entry represents a protein that belongs to the alpha/beta ...
 27-130 4.54e-03

Alpha/beta hydrolase domain; This entry represents a protein that belongs to the alpha/beta hydrolase superfamily. Although proteins in this family are uncharacterized they are likely to have an enzymatic activity.


Pssm-ID: 466557 [Multi-domain]  Cd Length: 193  Bit Score: 37.18  E-value: 4.54e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738  27 PRGVVVIAHG----------------LAEHGRR-----YGYVAQRlvdagylvaipdhvghgRSGGKRMRLRRFGEFTAD 85
Cdd:pfam20408   1 PKARLLLAHGagagmdspfmqamaaaLAARGIAvvrfnFPYMQRR-----------------RRTGKRRPPDRAPKLLEA 63

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1883737738  86 LDTVIAHVSDDALPTFLIGHSMGGCIAlDYALDHQDVlDGLILSG 130
Cdd:pfam20408  64 FRAVIAALRGPDLPLFIGGKSMGGRVA-SLLADDSGV-KGVIALG 106
PRK10566 PRK10566
esterase; Provisional
 25-113 4.75e-03

esterase; Provisional


Pssm-ID: 182555 [Multi-domain]  Cd Length: 249  Bit Score: 37.66  E-value: 4.75e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738  25 QAPRGVVVIAHGLAEHGRRYGYVAQRLVDAGYLVAIPDHVGHGR--SGGKRMRLRRF--------GEFTADLDTVIAH-- 92
Cdd:PRK10566   24 DTPLPTVFFYHGFTSSKLVYSYFAVALAQAGFRVIMPDAPMHGArfSGDEARRLNHFwqillqnmQEFPTLRAAIREEgw 103

                          90       100
                  ....*....|....*....|.
gi 1883737738  93 VSDDALPtfLIGHSMGGCIAL 113
Cdd:PRK10566  104 LLDDRLA--VGGASMGGMTAL 122
GrsT COG3208
Surfactin synthase thioesterase subunit [Secondary metabolites biosynthesis, transport and ...
 67-275 4.80e-03

Surfactin synthase thioesterase subunit [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 442441 [Multi-domain]  Cd Length: 237  Bit Score: 37.52  E-value: 4.80e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738  67 GRsgGKRMR---LRRFGEFTADLDTVIAHVSDdaLPTFLIGHSMGGCIALDYAL----DHQDVLDGLILSGAAvlpgddl 139
Cdd:COG3208    42 GR--GDRLGeppLTSLEELADDLAEELAPLLD--RPFALFGHSMGALLAFELARrlerRGRPLPAHLFVSGRR------- 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883737738 140 palairfakvigtvAPGLPTTALSSSSISrDPAVVAEydadpLVTRGKIPAGLGG----------------AMIATMQTF 203
Cdd:COG3208   111 --------------APHLPRRRRPLHDLS-DAELLAE-----LRRLGGTPEEVLAdpellelflpilradfRLLETYRYT 170

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1883737738 204 PArlPSLQLPILVMHGSEDALTDPkgsELVDRLADSTDK--TLVIYDG--LFheIFNEPERdvVLDEVVEWLGAHT 275
Cdd:COG3208   171 PG--PPLDCPITALGGDDDPLVSP---EELAAWREHTTGpfRLRVFPGghFF--LRDHPAE--LLALIRAALAALA 237
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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