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Conserved domains on  [gi|1883734432|gb|QMS99693|]
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tRNA (adenine-N1)-methyltransferase [Gordonia jinghuaiqii]

Protein Classification

tRNA (adenine-N1)-methyltransferase( domain architecture ID 11457537)

tRNA (adenine-N1)-methyltransferase, such as tRNA (adenine(58)-N(1))-methyltransferase, which is a class I SAM-dependent methyltransferase that catalyzes the methylation of N(1)-adenine at position 58 (m1A58) in tRNA using S-adenosyl-L-methionine (SAM or AdoMet) as the methyl donor

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Gcd14 COG2519
tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 ...
 10-260 8.88e-148

tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 N-methylase Trm61 is part of the Pathway/BioSystem: tRNA modification


:

Pssm-ID: 442009 [Multi-domain]  Cd Length: 249  Bit Score: 413.40  E-value: 8.88e-148
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432  10 GDRVQLTDAKGRKFTVLLDEGKLFHTHRGAIAHDDLIGSPEGSIVSATSGTQYLALRPLLVDYVLSMPRGAQVIYPKDAA 89
Cdd:COG2519     2 GDRVLLTDPKGRKYLVRLEEGKKFHTHKGIIDHDDLIGKPEGSVVTTSKGKEFLVLRPTLYDYVLSMKRGTQIIYPKDAG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432  90 QIVLEGDIFPGARVLEAGAGSGALTCSLLRAVGGDGEVVSFEIRDDHAEHAVRNVETFfgGRPDNWHLTVDDLANIDRDE 169
Cdd:COG2519    82 YIIARLDIFPGARVLEAGTGSGALTLALARAVGPEGKVYSYERREDFAEIARKNLERF--GLPDNVELKLGDIREGIDEG 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432 170 RFDRIILDMLAPWEQLDAVRAILKPGGVLTVYVATVTQLSRVMEALREQGcWTEPRAWETLLREWSAVGLAVRPEHKMQG 249
Cdd:COG2519   160 DVDAVFLDMPDPWEALEAVAKALKPGGVLVAYVPTVNQVSKLVEALRESG-FTDIEAVETLLREWKVEGLAVRPEHRMVG 238

                         250
                  ....*....|.
gi 1883734432 250 HTAFLITARRL 260
Cdd:COG2519   239 HTGFLVFARKL 249
 
Name Accession Description Interval E-value
Gcd14 COG2519
tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 ...
 10-260 8.88e-148

tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 N-methylase Trm61 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 442009 [Multi-domain]  Cd Length: 249  Bit Score: 413.40  E-value: 8.88e-148
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432  10 GDRVQLTDAKGRKFTVLLDEGKLFHTHRGAIAHDDLIGSPEGSIVSATSGTQYLALRPLLVDYVLSMPRGAQVIYPKDAA 89
Cdd:COG2519     2 GDRVLLTDPKGRKYLVRLEEGKKFHTHKGIIDHDDLIGKPEGSVVTTSKGKEFLVLRPTLYDYVLSMKRGTQIIYPKDAG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432  90 QIVLEGDIFPGARVLEAGAGSGALTCSLLRAVGGDGEVVSFEIRDDHAEHAVRNVETFfgGRPDNWHLTVDDLANIDRDE 169
Cdd:COG2519    82 YIIARLDIFPGARVLEAGTGSGALTLALARAVGPEGKVYSYERREDFAEIARKNLERF--GLPDNVELKLGDIREGIDEG 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432 170 RFDRIILDMLAPWEQLDAVRAILKPGGVLTVYVATVTQLSRVMEALREQGcWTEPRAWETLLREWSAVGLAVRPEHKMQG 249
Cdd:COG2519   160 DVDAVFLDMPDPWEALEAVAKALKPGGVLVAYVPTVNQVSKLVEALRESG-FTDIEAVETLLREWKVEGLAVRPEHRMVG 238

                         250
                  ....*....|.
gi 1883734432 250 HTAFLITARRL 260
Cdd:COG2519   239 HTGFLVFARKL 249
GCD14_N pfam14801
tRNA methyltransferase complex GCD14 subunit N-term; This is the N-terminal domain of GCD14, ...
 4-54 1.11e-27

tRNA methyltransferase complex GCD14 subunit N-term; This is the N-terminal domain of GCD14, itself a subunit of the tRNA methyltransferase complex that is required for 1-methyladenosine modification and maturation of initiator methionyl-tRNA. The exact function of the N-terminus is not known but it is necessary for maintaining the overall folding and for full enzymatic activity.


Pssm-ID: 434222  Cd Length: 51  Bit Score: 101.04  E-value: 1.11e-27
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1883734432   4 TGPFAVGDRVQLTDAKGRKFTVLLDEGKLFHTHRGAIAHDDLIGSPEGSIV 54
Cdd:pfam14801   1 RGPFRAGDRVQLTDPKGRKHTITLEPGGEFHTHRGAIRHDDLIGRPEGSVV 51
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 102-198 1.08e-12

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 62.83  E-value: 1.08e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432 102 RVLEAGAGSGALTCSLLRavGGDGEVVSFEIRDDHAEHAVRNVEtffGGRPDNWHLTVDDLANI--DRDERFDRIILD-- 177
Cdd:cd02440     1 RVLDLGCGTGALALALAS--GPGARVTGVDISPVALELARKAAA---ALLADNVEVLKGDAEELppEADESFDVIISDpp 75

                          90       100
                  ....*....|....*....|....*
gi 1883734432 178 ----MLAPWEQLDAVRAILKPGGVL 198
Cdd:cd02440    76 lhhlVEDLARFLEEARRLLKPGGVL 100
PRK13944 PRK13944
protein-L-isoaspartate O-methyltransferase; Provisional
 99-200 3.10e-04

protein-L-isoaspartate O-methyltransferase; Provisional


Pssm-ID: 140001  Cd Length: 205  Bit Score: 40.95  E-value: 3.10e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432  99 PGARVLEAGAGSGALTCSLLRAVGGDGEVVSFEIRDDHAEHAVRNVETF-FGGRPDNWHltVDDLANIDRDERFDRIILD 177
Cdd:PRK13944   72 PGMKILEVGTGSGYQAAVCAEAIERRGKVYTVEIVKELAIYAAQNIERLgYWGVVEVYH--GDGKRGLEKHAPFDAIIVT 149

                          90       100
                  ....*....|....*....|....*.
gi 1883734432 178 MLA---PWEQLDAvraiLKPGGVLTV 200
Cdd:PRK13944  150 AAAstiPSALVRQ----LKDGGVLVI 171
rADc smart00650
Ribosomal RNA adenine dimethylases;
88-136 2.67e-03

Ribosomal RNA adenine dimethylases;


Pssm-ID: 128898  Cd Length: 169  Bit Score: 37.88  E-value: 2.67e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 1883734432   88 AAQIVLEGDIFPGARVLEAGAGSGALTCSLLRAVggdGEVVSFEIrDDH 136
Cdd:smart00650   2 IDKIVRAANLRPGDTVLEIGPGKGALTEELLERA---KRVTAIEI-DPR 46
 
Name Accession Description Interval E-value
Gcd14 COG2519
tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 ...
 10-260 8.88e-148

tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 N-methylase Trm61 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 442009 [Multi-domain]  Cd Length: 249  Bit Score: 413.40  E-value: 8.88e-148
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432  10 GDRVQLTDAKGRKFTVLLDEGKLFHTHRGAIAHDDLIGSPEGSIVSATSGTQYLALRPLLVDYVLSMPRGAQVIYPKDAA 89
Cdd:COG2519     2 GDRVLLTDPKGRKYLVRLEEGKKFHTHKGIIDHDDLIGKPEGSVVTTSKGKEFLVLRPTLYDYVLSMKRGTQIIYPKDAG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432  90 QIVLEGDIFPGARVLEAGAGSGALTCSLLRAVGGDGEVVSFEIRDDHAEHAVRNVETFfgGRPDNWHLTVDDLANIDRDE 169
Cdd:COG2519    82 YIIARLDIFPGARVLEAGTGSGALTLALARAVGPEGKVYSYERREDFAEIARKNLERF--GLPDNVELKLGDIREGIDEG 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432 170 RFDRIILDMLAPWEQLDAVRAILKPGGVLTVYVATVTQLSRVMEALREQGcWTEPRAWETLLREWSAVGLAVRPEHKMQG 249
Cdd:COG2519   160 DVDAVFLDMPDPWEALEAVAKALKPGGVLVAYVPTVNQVSKLVEALRESG-FTDIEAVETLLREWKVEGLAVRPEHRMVG 238

                         250
                  ....*....|.
gi 1883734432 250 HTAFLITARRL 260
Cdd:COG2519   239 HTGFLVFARKL 249
GCD14_N pfam14801
tRNA methyltransferase complex GCD14 subunit N-term; This is the N-terminal domain of GCD14, ...
 4-54 1.11e-27

tRNA methyltransferase complex GCD14 subunit N-term; This is the N-terminal domain of GCD14, itself a subunit of the tRNA methyltransferase complex that is required for 1-methyladenosine modification and maturation of initiator methionyl-tRNA. The exact function of the N-terminus is not known but it is necessary for maintaining the overall folding and for full enzymatic activity.


Pssm-ID: 434222  Cd Length: 51  Bit Score: 101.04  E-value: 1.11e-27
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1883734432   4 TGPFAVGDRVQLTDAKGRKFTVLLDEGKLFHTHRGAIAHDDLIGSPEGSIV 54
Cdd:pfam14801   1 RGPFRAGDRVQLTDPKGRKHTITLEPGGEFHTHRGAIRHDDLIGRPEGSVV 51
GCD14 pfam08704
tRNA methyltransferase complex GCD14 subunit; GCD14 is a subunit of the tRNA methyltransferase ...
 63-258 3.34e-23

tRNA methyltransferase complex GCD14 subunit; GCD14 is a subunit of the tRNA methyltransferase complex and is required for 1-methyladenosine modification and maturation of initiator methionyl-tRNA.


Pssm-ID: 312288  Cd Length: 242  Bit Score: 94.87  E-value: 3.34e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432  63 LALRPLLvdYVLSMPRGAQVIYPKDAAQIVLEGDIFPGARVLEAGAGSGALTCSLLRAVGGDGEVVSFEIrddHAEHAVR 142
Cdd:pfam08704   6 LQPTPEL--WTLNLPHRTQILYTPDISLITMMLELRPGSVVCESGTGSGSLSHAIIRTVAPTGHLFTFEF---HEQRADK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432 143 NVETFFGGRPDNW-HLTVDDLAN----IDRDERFDRIILDMLAPWEQL-DAVRAILKPGGVLTVYVATVTQLSRVMEALR 216
Cdd:pfam08704  81 AREEFREHGIDQLvTVTHRDVCKegflTEVSGKADAVFLDLPSPWEAVpHAWKALKVEGGRFCSFSPCIEQVQRTCQALA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432 217 EQGcWTEPRAWETLLREW----------------------------------------SAVGLAVRPEHKMQGHTAFLIT 256
Cdd:pfam08704 161 ELG-FTEISTLEVLLRVYdvrtvslpvidlgidrekenertrteglsnddksednsgnSMLGTALKPMSEAVGHTGYLTF 239


                  ..
gi 1883734432 257 AR 258
Cdd:pfam08704 240 AT 241
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 102-198 1.08e-12

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 62.83  E-value: 1.08e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432 102 RVLEAGAGSGALTCSLLRavGGDGEVVSFEIRDDHAEHAVRNVEtffGGRPDNWHLTVDDLANI--DRDERFDRIILD-- 177
Cdd:cd02440     1 RVLDLGCGTGALALALAS--GPGARVTGVDISPVALELARKAAA---ALLADNVEVLKGDAEELppEADESFDVIISDpp 75

                          90       100
                  ....*....|....*....|....*
gi 1883734432 178 ----MLAPWEQLDAVRAILKPGGVL 198
Cdd:cd02440    76 lhhlVEDLARFLEEARRLLKPGGVL 100
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 99-219 2.65e-10

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 57.31  E-value: 2.65e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432  99 PGARVLEAGAGSGALTCSLLRAvggDGEVVSFEIRDDHAEHAVRNVEtffgGRPDNWHLTVDDLANID-RDERFDRII-- 175
Cdd:COG2226    22 PGARVLDLGCGTGRLALALAER---GARVTGVDISPEMLELARERAA----EAGLNVEFVVGDAEDLPfPDGSFDLVIss 94

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1883734432 176 --LDMLAPWEQ-LDAVRAILKPGGVLTVYVATVTQLSRVMEALREQG 219
Cdd:COG2226    95 fvLHHLPDPERaLAEIARVLKPGGRLVVVDFSPPDLAELEELLAEAG 141
Cfa COG2230
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ...
 99-198 7.37e-10

Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];


Pssm-ID: 441831 [Multi-domain]  Cd Length: 158  Bit Score: 56.48  E-value: 7.37e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432  99 PGARVLEAGAGSGALTCSLLRAVGGDgeVVSFEIRDDHAEHAVRNVETFfgGRPDNWHLTVDDLANIDRDERFDRII-LD 177
Cdd:COG2230    51 PGMRVLDIGCGWGGLALYLARRYGVR--VTGVTLSPEQLEYARERAAEA--GLADRVEVRLADYRDLPADGQFDAIVsIG 126

                          90       100
                  ....*....|....*....|....*..
gi 1883734432 178 ML-----APWEQ-LDAVRAILKPGGVL 198
Cdd:COG2230   127 MFehvgpENYPAyFAKVARLLKPGGRL 153
UbiG COG2227
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
 93-198 1.04e-08

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 52.33  E-value: 1.04e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432  93 LEGDIFPGARVLEAGAGSGALTCSLLRAvggdG-EVVSFEIRDDHAEHAVRNVETFfggrpdNWHLTVDDLANID-RDER 170
Cdd:COG2227    18 LARLLPAGGRVLDVGCGTGRLALALARR----GaDVTGVDISPEALEIARERAAEL------NVDFVQGDLEDLPlEDGS 87

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1883734432 171 FDRII-LDMLA----PWEQLDAVRAILKPGGVL 198
Cdd:COG2227    88 FDLVIcSEVLEhlpdPAALLRELARLLKPGGLL 120
PCMT pfam01135
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);
96-202 1.14e-07

Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);


Pssm-ID: 395902 [Multi-domain]  Cd Length: 205  Bit Score: 51.21  E-value: 1.14e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432  96 DIFPGARVLEAGAGSGALTCSLLRAVGGDGEVVSFEIRDDHAEHAVRNVETFfggRPDNWHLTVDDlANIDRDER--FDR 173
Cdd:pfam01135  70 ELKPGMRVLEIGSGSGYLTACFARMVGEVGRVVSIEHIPELVEIARRNLEKL---GLENVIVVVGD-GRQGWPEFapYDA 145

                          90       100
                  ....*....|....*....|....*....
gi 1883734432 174 IILDMLAPwEQLDAVRAILKPGGVLTVYV 202
Cdd:pfam01135 146 IHVGAAAP-EIPEALIDQLKEGGRLVIPV 173
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 103-196 1.47e-07

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 48.33  E-value: 1.47e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432 103 VLEAGAGSGALTCSLLRAVGgdGEVVSFEIRDDHAEHAVRNVEtffgGRPDNWHLTVDDLANID-RDERFDRII----LD 177
Cdd:pfam13649   1 VLDLGCGTGRLTLALARRGG--ARVTGVDLSPEMLERARERAA----EAGLNVEFVQGDAEDLPfPDGSFDLVVssgvLH 74

                          90       100
                  ....*....|....*....|..
gi 1883734432 178 MLAPWEQLDAVRAI---LKPGG 196
Cdd:pfam13649  75 HLPDPDLEAALREIarvLKPGG 96
TrmR COG4122
tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; ...
 102-217 6.17e-07

tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; tRNA 5-hydroxyU34 O-methylase TrmR/YrrM is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 443298  Cd Length: 173  Bit Score: 48.26  E-value: 6.17e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432 102 RVLEAGAGSGALTCSLLRAVGGDGEVVSFEIRDDHAEHAVRNVETFfgGRPDNWHLTVDD-LANIDR--DERFDRIILDm 178
Cdd:COG4122    19 RILEIGTGTGYSTLWLARALPDDGRLTTIEIDPERAAIARENFARA--GLADRIRLILGDaLEVLPRlaDGPFDLVFID- 95

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1883734432 179 lAPWEQ----LDAVRAILKPGGVLTV-------YVATVTQLSRVMEALRE 217
Cdd:COG4122    96 -ADKSNypdyLELALPLLRPGGLIVAdnvlwhgRVADPARRDPSTRAIRE 144
TrmN6 COG4123
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) ...
 99-219 7.34e-07

tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) A37 N6-methylase TrmN6 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 443299 [Multi-domain]  Cd Length: 238  Bit Score: 48.99  E-value: 7.34e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432  99 PGARVLEAGAGSGALTCsLLRAVGGDGEVVSFEIRDDHAEHAVRNVE-TFFGGRPDNWHLTVDDLANIDRDERFDRII-- 175
Cdd:COG4123    37 KGGRVLDLGTGTGVIAL-MLAQRSPGARITGVEIQPEAAELARRNVAlNGLEDRITVIHGDLKEFAAELPPGSFDLVVsn 115

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1883734432 176 ---------------------LDMLAPWEQL-DAVRAILKPGGVLTVyVATVTQLSRVMEALREQG 219
Cdd:COG4123   116 ppyfkagsgrkspdearaiarHEDALTLEDLiRAAARLLKPGGRFAL-IHPAERLAEILAALRKYG 180
SmtA COG0500
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ...
 99-275 2.49e-06

SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];


Pssm-ID: 440266 [Multi-domain]  Cd Length: 199  Bit Score: 47.22  E-value: 2.49e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432  99 PGARVLEAGAGSGALTCSLLRAVGGDgeVVSFEIRDDHAEHAVRNVETFFggrPDNWHLTVDDLANIDR--DERFDRIIL 176
Cdd:COG0500    26 KGGRVLDLGCGTGRNLLALAARFGGR--VIGIDLSPEAIALARARAAKAG---LGNVEFLVADLAELDPlpAESFDLVVA 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432 177 DMLAPWEQ-------LDAVRAILKPGGVLtVYVATVTQ--LSRVMEALREQGCWTEPRAWEtllrewsaVGLAVRPEHKM 247
Cdd:COG0500   101 FGVLHHLPpeerealLRELARALKPGGVL-LLSASDAAaaLSLARLLLLATASLLELLLLL--------RLLALELYLRA 171

                         170       180
                  ....*....|....*....|....*...
gi 1883734432 248 QGHTAFLITARRLADGTTTLRPQRRPSK 275
Cdd:COG0500   172 LLAAAATEDLRSDALLESANALEYLLSK 199
Tam COG4106
Trans-aconitate methyltransferase [Energy production and conversion];
99-198 3.32e-06

Trans-aconitate methyltransferase [Energy production and conversion];


Pssm-ID: 443282 [Multi-domain]  Cd Length: 100  Bit Score: 44.81  E-value: 3.32e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432  99 PGARVLEAGAGSGALTCSLLRAVGGdGEVVSFEIRDDHAEHAVRNVetffggrpDNWHLTVDDLANIDRDERFDRIILDM 178
Cdd:COG4106     1 PPRRVLDLGCGTGRLTALLAERFPG-ARVTGVDLSPEMLARARARL--------PNVRFVVADLRDLDPPEPFDLVVSNA 71

                          90       100
                  ....*....|....*....|....*
gi 1883734432 179 LAPW-----EQLDAVRAILKPGGVL 198
Cdd:COG4106    72 ALHWlpdhaALLARLAAALAPGGVL 96
COG4076 COG4076
Predicted RNA methylase [General function prediction only];
97-276 3.73e-06

Predicted RNA methylase [General function prediction only];


Pssm-ID: 443253 [Multi-domain]  Cd Length: 230  Bit Score: 46.95  E-value: 3.73e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432  97 IFPGARVLEAGAGSGALTCSLLRAvgGDGEVVSFEIRDDHAEHAVRNVETFfgGRPDNWHLTVDDLANIDRDERFDRIIL 176
Cdd:COG4076    33 VKPGDVVLDIGTGSGLLSMLAARA--GAKKVYAVEVNPDIAAVARRIIAAN--GLSDRITVINADATDLDLPEKADVIIS 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432 177 DMLAPW----EQL----DAVRAILKPGGVL-----TVYVATVtQLSRVMEALREQGCWTE-PRAWETLL-REWSAVGLAV 241
Cdd:COG4076   109 EMLDTAlldeGQVpilnHARKRLLKPGGRIiperiTNAAQPV-ESPVDAEGFEDWQFDGFdFRLFGFLLyAEPLLHLTRL 187

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1883734432 242 RPEHKMQGHTAFLItarRLADGTTTLRPQRRPSKG 276
Cdd:COG4076   188 VRTPLLLLLLPTAF---DEFPFDLASQRATSAQRQ 219
Pcm COG2518
Protein-L-isoaspartate O-methyltransferase [Posttranslational modification, protein turnover, ...
 96-216 5.76e-06

Protein-L-isoaspartate O-methyltransferase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 442008 [Multi-domain]  Cd Length: 197  Bit Score: 45.85  E-value: 5.76e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432  96 DIFPGARVLEAGAGSG---ALTCSLLravggdGEVVSFEIRDDHAEHAVRNVETFfggRPDNWHLTVDDLANIDRDE-RF 171
Cdd:COG2518    63 DLKPGDRVLEIGTGSGyqaAVLARLA------GRVYSVERDPELAERARERLAAL---GYDNVTVRVGDGALGWPEHaPF 133

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1883734432 172 DRIILDMlAPWEQLDAVRAILKPGGVLtvyVATVTQlSRVMEALR 216
Cdd:COG2518   134 DRIIVTA-AAPEVPEALLEQLAPGGRL---VAPVGE-GGVQRLVL 173
COG2263 COG2263
Predicted RNA methylase [General function prediction only];
88-175 5.84e-06

Predicted RNA methylase [General function prediction only];


Pssm-ID: 441864 [Multi-domain]  Cd Length: 199  Bit Score: 46.05  E-value: 5.84e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432  88 AAQIV----LEGDIfPGARVLEAGAGSGALT-CSLLRavgGDGEVVSFEIRDDHAEHAVRNVETFFGgrpdNWHLTVDDL 162
Cdd:COG2263    31 AAELLhlayLRGDI-EGKTVLDLGCGTGMLAiGAALL---GAKKVVGVDIDPEALEIARENAERLGV----RVDFIRADV 102

                          90
                  ....*....|...
gi 1883734432 163 ANIDRDERFDRII 175
Cdd:COG2263   103 TRIPLGGSVDTVV 115
Methyltransf_12 pfam08242
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 104-198 5.84e-05

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 400515 [Multi-domain]  Cd Length: 98  Bit Score: 41.20  E-value: 5.84e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432 104 LEAGAGSGALTCSLLRAVGGdGEVVSFEIRDDHAEHAVRNVETFFGGRPDNWHLTVDDLANIDrDERFDRII----LDML 179
Cdd:pfam08242   1 LEIGCGTGTLLRALLEALPG-LEYTGLDISPAALEAARERLAALGLLNAVRVELFQLDLGELD-PGSFDVVVasnvLHHL 78

                          90       100
                  ....*....|....*....|
gi 1883734432 180 APWEQ-LDAVRAILKPGGVL 198
Cdd:pfam08242  79 ADPRAvLRNIRRLLKPGGVL 98
CobL COG2242
Precorrin-6B methylase 2 [Coenzyme transport and metabolism]; Precorrin-6B methylase 2 is part ...
 96-219 9.22e-05

Precorrin-6B methylase 2 [Coenzyme transport and metabolism]; Precorrin-6B methylase 2 is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 441843 [Multi-domain]  Cd Length: 403  Bit Score: 43.23  E-value: 9.22e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432  96 DIFPGARVLEAGAGSGALTCSLLRAVGGdGEVVSFEIRDDHAEHAVRNVETFfgGRPDnwhLTV------DDLANIdrdE 169
Cdd:COG2242   244 ALRPGDVLWDIGAGSGSVSIEAARLAPG-GRVYAIERDPERAALIRANARRF--GVPN---VEVvegeapEALADL---P 314

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1883734432 170 RFDRII-------LDMLapweqLDAVRAILKPGGVLTVYVATVTQLSRVMEALREQG 219
Cdd:COG2242   315 DPDAVFiggsggnLPEI-----LEACWARLRPGGRLVANAVTLETLALALEALAELG 366
Methyltransf_31 pfam13847
Methyltransferase domain; This family appears to have methyltransferase activity.
 97-232 1.79e-04

Methyltransferase domain; This family appears to have methyltransferase activity.


Pssm-ID: 463998 [Multi-domain]  Cd Length: 150  Bit Score: 40.86  E-value: 1.79e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432  97 IFPGARVLEAGAGSGALTCSLLRAVGGDGEVVSFEIRDD-------HAE-HAVRNVEtFFGGRpdnwhltVDDLANIDRD 168
Cdd:pfam13847   1 IDKGMRVLDLGCGTGHLSFELAEELGPNAEVVGIDISEEaiekareNAQkLGFDNVE-FEQGD-------IEELPELLED 72

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1883734432 169 ERFDRIILD-----MLAPWEQLDAVRAILKPGGVLTV-YVATVTQLSRVMEALRE--QGCWTEPRAWETLLR 232
Cdd:pfam13847  73 DKFDVVISNcvlnhIPDPDKVLQEILRVLKPGGRLIIsDPDSLAELPAHVKEDSTyyAGCVGGAILKKKLYE 144
PRK13944 PRK13944
protein-L-isoaspartate O-methyltransferase; Provisional
 99-200 3.10e-04

protein-L-isoaspartate O-methyltransferase; Provisional


Pssm-ID: 140001  Cd Length: 205  Bit Score: 40.95  E-value: 3.10e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432  99 PGARVLEAGAGSGALTCSLLRAVGGDGEVVSFEIRDDHAEHAVRNVETF-FGGRPDNWHltVDDLANIDRDERFDRIILD 177
Cdd:PRK13944   72 PGMKILEVGTGSGYQAAVCAEAIERRGKVYTVEIVKELAIYAAQNIERLgYWGVVEVYH--GDGKRGLEKHAPFDAIIVT 149

                          90       100
                  ....*....|....*....|....*.
gi 1883734432 178 MLA---PWEQLDAvraiLKPGGVLTV 200
Cdd:PRK13944  150 AAAstiPSALVRQ----LKDGGVLVI 171
PrmA COG2264
Ribosomal protein L11 methylase PrmA [Translation, ribosomal structure and biogenesis];
93-220 3.48e-04

Ribosomal protein L11 methylase PrmA [Translation, ribosomal structure and biogenesis];


Pssm-ID: 441865 [Multi-domain]  Cd Length: 284  Bit Score: 41.31  E-value: 3.48e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432  93 LEGDIFPGARVLEAGAGSG--ALTCSLLravgGDGEVVSFEIrDdhaEHAVRNVEtffggrpDNWHL-TVDD-----LAN 164
Cdd:COG2264   142 LEKLLKPGKTVLDVGCGSGilAIAAAKL----GAKRVLAVDI-D---PVAVEAAR-------ENAELnGVEDrievvLGD 206

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1883734432 165 IDRDERFDRI-------ILDMLAPweqldAVRAILKPGGVLtvyVA---TVTQLSRVMEALREQGC 220
Cdd:COG2264   207 LLEDGPYDLVvanilanPLIELAP-----DLAALLKPGGYL---ILsgiLEEQADEVLAAYEAAGF 264
COG3963 COG3963
Phosphatidylethanolamine N-methyltransferase [Lipid transport and metabolism];
88-219 3.94e-04

Phosphatidylethanolamine N-methyltransferase [Lipid transport and metabolism];


Pssm-ID: 443163  Cd Length: 193  Bit Score: 40.58  E-value: 3.94e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432  88 AAQIVLEGDifpgARVLEAGAGSGALTCSLLRAVGGDGEVVSFEIRDDHAEHavrnVETFFGGrpdnwhLTV--DDLANI 165
Cdd:COG3963    38 ASEVDWSGA----GPVVELGPGTGVFTRAILARGVPDARLLAVEINPEFAEH----LRRRFPR------VTVvnGDAEDL 103

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1883734432 166 DR------DERFDRII--LDMLA-PWEQ----LDAVRAILKPGGVLTVYvaTVTQLSRVMEALREQG 219
Cdd:COG3963   104 AEllaehgIGKVDAVVsgLPLLSfPPELrraiLDAAFRVLAPGGVFVQF--TYSPRSPVPRKLLRRG 168
PRK08317 PRK08317
hypothetical protein; Provisional
 96-196 5.90e-04

hypothetical protein; Provisional


Pssm-ID: 181382 [Multi-domain]  Cd Length: 241  Bit Score: 40.31  E-value: 5.90e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432  96 DIFPGARVLEAGAGSGALTCSLLRAVGGDGEVVSFEIRDDHAEHAVRNVEtfFGGRPDNWHLtvDDLANID-RDERFDRI 174
Cdd:PRK08317   16 AVQPGDRVLDVGCGPGNDARELARRVGPEGRVVGIDRSEAMLALAKERAA--GLGPNVEFVR--GDADGLPfPDGSFDAV 91

                          90       100
                  ....*....|....*....|....*..
gi 1883734432 175 ILD-----MLAPWEQLDAVRAILKPGG 196
Cdd:PRK08317   92 RSDrvlqhLEDPARALAEIARVLRPGG 118
Methyltransf_23 pfam13489
Methyltransferase domain; This family appears to be a methyltransferase domain.
 85-241 6.23e-04

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 404385 [Multi-domain]  Cd Length: 162  Bit Score: 39.33  E-value: 6.23e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432  85 PKDAAQIVLE--GDIFPGARVLEAGAGSGALtCSLLRAVGGDgeVVSFEIRDDHAEHAVRNVEtffggrpdnwHLTVDDL 162
Cdd:pfam13489   6 ERLLADLLLRllPKLPSPGRVLDFGCGTGIF-LRLLRAQGFS--VTGVDPSPIAIERALLNVR----------FDQFDEQ 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432 163 ANIDRDERFDRII----LDMLAPW-EQLDAVRAILKPGGVLTVYVATVTQLSRV------MEALREQGCWTEPRawETLL 231
Cdd:pfam13489  73 EAAVPAGKFDVIVarevLEHVPDPpALLRQIAALLKPGGLLLLSTPLASDEADRlllewpYLRPRNGHISLFSA--RSLK 150

                         170
                  ....*....|
gi 1883734432 232 REWSAVGLAV 241
Cdd:pfam13489 151 RLLEEAGFEV 160
prmA PRK00517
50S ribosomal protein L11 methyltransferase;
93-219 1.60e-03

50S ribosomal protein L11 methyltransferase;


Pssm-ID: 234786 [Multi-domain]  Cd Length: 250  Bit Score: 38.98  E-value: 1.60e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432  93 LEGDIFPGARVLEAGAGSG--ALTCSLLRAvggdGEVVSFEIrDDHA-----EHAVRN-VETFFGGRPDNwhLTVDD-LA 163
Cdd:PRK00517  113 LEKLVLPGKTVLDVGCGSGilAIAAAKLGA----KKVLAVDI-DPQAveaarENAELNgVELNVYLPQGD--LKADViVA 185

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432 164 NIDRDerfdriILDMLAPweqldAVRAILKPGGvltvYVAT----VTQLSRVMEALREQG 219
Cdd:PRK00517  186 NILAN------PLLELAP-----DLARLLKPGG----RLILsgilEEQADEVLEAYEEAG 230
RsmA COG0030
16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase ...
 88-132 1.72e-03

16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity) [Translation, ribosomal structure and biogenesis]; 16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity) is part of the Pathway/BioSystem: 16S rRNA modification


Pssm-ID: 439801 [Multi-domain]  Cd Length: 270  Bit Score: 38.95  E-value: 1.72e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1883734432  88 AAQIVLEGDIFPGARVLEAGAGSGALTCSLLRAVggdGEVVSFEI 132
Cdd:COG0030    26 IRRIVDAAGITPGDTVLEIGPGLGALTRALLERA---ARVTAVEI 67
cbiT PRK00377
cobalt-precorrin-6Y C(15)-methyltransferase; Provisional
 97-223 1.81e-03

cobalt-precorrin-6Y C(15)-methyltransferase; Provisional


Pssm-ID: 234740  Cd Length: 198  Bit Score: 38.62  E-value: 1.81e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432  97 IFPGARVLEAGAGSGALTCSLLRAVGGDGEVVSFEIRDDHAEHAVRNVETFfgGRPDNWHLTVDD----LANIdrDERFD 172
Cdd:PRK00377   38 LRKGDMILDIGCGTGSVTVEASLLVGETGKVYAVDKDEKAINLTRRNAEKF--GVLNNIVLIKGEapeiLFTI--NEKFD 113

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432 173 RIILD---------MLAPWEqldavraILKPGGVLTVYVATVTQLSRVMEALREQGCWTE 223
Cdd:PRK00377  114 RIFIGggseklkeiISASWE-------IIKKGGRIVIDAILLETVNNALSALENIGFNLE 166
PRK14967 PRK14967
putative methyltransferase; Provisional
 89-230 1.92e-03

putative methyltransferase; Provisional


Pssm-ID: 184931 [Multi-domain]  Cd Length: 223  Bit Score: 38.50  E-value: 1.92e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432  89 AQIVLEGDIFPGARVLEAGAGSGALtcSLLRAVGGDGEVVSFEIrddhAEHAVRN--VETFFGGRPDNWHLtvDDLANID 166
Cdd:PRK14967   26 ADALAAEGLGPGRRVLDLCTGSGAL--AVAAAAAGAGSVTAVDI----SRRAVRSarLNALLAGVDVDVRR--GDWARAV 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432 167 RDERFD-------------------------------RIILDMLApweqlDAVRAILKPGGVLTVYVATVTQLSRVMEAL 215
Cdd:PRK14967   98 EFRPFDvvvsnppyvpappdappsrgparawdagpdgRAVLDRLC-----DAAPALLAPGGSLLLVQSELSGVERTLTRL 172

                         170
                  ....*....|....*
gi 1883734432 216 REQGCWTEPRAWETL 230
Cdd:PRK14967  173 SEAGLDAEVVASQWI 187
rADc smart00650
Ribosomal RNA adenine dimethylases;
88-136 2.67e-03

Ribosomal RNA adenine dimethylases;


Pssm-ID: 128898  Cd Length: 169  Bit Score: 37.88  E-value: 2.67e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 1883734432   88 AAQIVLEGDIFPGARVLEAGAGSGALTCSLLRAVggdGEVVSFEIrDDH 136
Cdd:smart00650   2 IDKIVRAANLRPGDTVLEIGPGKGALTEELLERA---KRVTAIEI-DPR 46
TrmA COG2265
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure ...
 23-177 2.67e-03

tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure and biogenesis]; tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 441866 [Multi-domain]  Cd Length: 377  Bit Score: 38.62  E-value: 2.67e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432  23 FTVLLDEGKLFHTHRGAIAHddligspegsiVSATSGTQYLALRPLLVDYVLSM-------PRGAQVIYpkdaaQIVLEG 95
Cdd:COG2265   165 LPALRELLAELGARRGELRH-----------LVVRAGRDYLTERLGGLTFRISPgsffqvnPEQAEALY-----AAALEW 228

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432  96 -DIFPGARVLEAGAGSGALTCSLLRAVGgdgEVVSFEIRDDHAEHAVRNVE-------TFFGGRpdnwhlTVDDLANIDR 167
Cdd:COG2265   229 lDLTGGERVLDLYCGVGTFALPLARRAK---KVIGVEIVPEAVEDARENARlnglknvEFVAGD------LEEVLPELLW 299

                         170
                  ....*....|
gi 1883734432 168 DERFDRIILD 177
Cdd:COG2265   300 GGRPDVVVLD 309
PRK13942 PRK13942
protein-L-isoaspartate O-methyltransferase; Provisional
 96-212 3.21e-03

protein-L-isoaspartate O-methyltransferase; Provisional


Pssm-ID: 184409  Cd Length: 212  Bit Score: 38.07  E-value: 3.21e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432  96 DIFPGARVLEAGAGSGALTCSLLRAVGGDGEVVSFEIRDDHAEHAVRNVETFfgGRpDNWHLTVDD-LANIDRDERFDRI 174
Cdd:PRK13942   73 DLKEGMKVLEIGTGSGYHAAVVAEIVGKSGKVVTIERIPELAEKAKKTLKKL--GY-DNVEVIVGDgTLGYEENAPYDRI 149

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1883734432 175 ILDMLAP------WEQldavraiLKPGGVLTVYVATVTQ-LSRVM 212
Cdd:PRK13942  150 YVTAAGPdipkplIEQ-------LKDGGIMVIPVGSYSQeLIRVE 187
COG4976 COG4976
Predicted methyltransferase, contains TPR repeat [General function prediction only];
85-198 6.57e-03

Predicted methyltransferase, contains TPR repeat [General function prediction only];


Pssm-ID: 444001 [Multi-domain]  Cd Length: 181  Bit Score: 36.51  E-value: 6.57e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883734432  85 PKDAAQIVLEG-DIFPGARVLEAGAGSGALTcSLLRAVGGDgeVVSFEIRDDHAEHAVRNvetffgGRPDNWHltVDDLA 163
Cdd:COG4976    31 PALLAEELLARlPPGPFGRVLDLGCGTGLLG-EALRPRGYR--LTGVDLSEEMLAKAREK------GVYDRLL--VADLA 99

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1883734432 164 NIDR-DERFDRII----LDMLAPWEQ-LDAVRAILKPGGVL 198
Cdd:COG4976   100 DLAEpDGRFDLIVaadvLTYLGDLAAvFAGVARALKPGGLF 140
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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