glycosyl transferase family 1 [Klebsiella pneumoniae]
Protein Classification
glycosyltransferase family protein( domain architecture ID 56)
glycosyltransferase family protein may synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein
List of domain hits
| Name | Accession | Description | Interval | E-value | ||||||
| Glycosyltransferase_GTB-type super family | cl10013 | glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases ... |
3-310 | 4.90e-11 | ||||||
glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The actual alignment was detected with superfamily member cd03801: Pssm-ID: 471961 [Multi-domain] Cd Length: 366 Bit Score: 63.71 E-value: 4.90e-11
|
||||||||||
| Name | Accession | Description | Interval | E-value | ||||||
| GT4_PimA-like | cd03801 | phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 ... |
3-310 | 4.90e-11 | ||||||
phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea. Pssm-ID: 340831 [Multi-domain] Cd Length: 366 Bit Score: 63.71 E-value: 4.90e-11
|
||||||||||
| RfaB | COG0438 | Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ... |
231-311 | 5.81e-05 | ||||||
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; Pssm-ID: 440207 [Multi-domain] Cd Length: 123 Bit Score: 42.28 E-value: 5.81e-05
|
||||||||||
| Name | Accession | Description | Interval | E-value | ||||||
| GT4_PimA-like | cd03801 | phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 ... |
3-310 | 4.90e-11 | ||||||
phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea. Pssm-ID: 340831 [Multi-domain] Cd Length: 366 Bit Score: 63.71 E-value: 4.90e-11
|
||||||||||
| RfaB | COG0438 | Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ... |
231-311 | 5.81e-05 | ||||||
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; Pssm-ID: 440207 [Multi-domain] Cd Length: 123 Bit Score: 42.28 E-value: 5.81e-05
|
||||||||||
| Blast search parameters | ||||
|
