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Conserved domains on  [gi|1830048181|gb|QIY30972|]
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YjdF family protein [Bacillus anthracis]

Protein Classification

YjdF family protein( domain architecture ID 10567862)

YjdF family protein similar to Bacillus subtilis protein YjdF

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
DUF2992 pfam11208
Protein of unknown function (DUF2992); This bacterial family of proteins has no known function. ...
3-135 1.52e-42

Protein of unknown function (DUF2992); This bacterial family of proteins has no known function. However, the cis-regulatory yjdF motif, just upstream from the gene encoding the proteins for this family, is a small non-coding RNA, Rfam:RF01764. The yjdF motif is found in many Firmicutes, including Bacillus subtilis. In most cases, it resides in potential 5' UTRs of homologs of the yjdF gene whose function is unknown. However, in Streptococcus thermophilus, a yjdF RNA motif is associated with an operon whose protein products synthesize nicotinamide adenine dinucleotide (NAD+). Also, the S. thermophilus yjdF RNA lacks typical yjdF motif consensus features downstream of and including the P4 stem. Thus, if yjdF RNAs are riboswitch aptamers, the S. thermophilus RNAs might sense a distinct compound that structurally resembles the ligand bound by other yjdF RNAs. On the ohter hand, perhaps these RNAs have an alternative solution forming a similar binding site, as is observed with some SAM riboswitches.


:

Pssm-ID: 402678  Cd Length: 132  Bit Score: 136.91  E-value: 1.52e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830048181   3 LTVYHDGQFFVGIITCKEKGKLYGARYIFGAEPSDEEVLIFVNGSMLAYFQQFAKCGVEVKEKqrPKNIKRIIRQAVKEV 82
Cdd:pfam11208   1 LTVFFDGPFWVGVFEREEGGKYKVARVTFGAEPKDYEVYEFILKNYSRLRFSPPVEAVERKEK--RINPKRLQREAKKEL 78
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1830048181  83 NVSRF-TKAQEAISLSYELHKQEKKVQSKEKREAEKQRRRLIKVQKAKQKHRGH 135
Cdd:pfam11208  79 RQRGIgTKAQQALKLQHEQRKLERKKRSKEQREAEKERRFQLKQQKRKEKHRGH 132
 
Name Accession Description Interval E-value
DUF2992 pfam11208
Protein of unknown function (DUF2992); This bacterial family of proteins has no known function. ...
3-135 1.52e-42

Protein of unknown function (DUF2992); This bacterial family of proteins has no known function. However, the cis-regulatory yjdF motif, just upstream from the gene encoding the proteins for this family, is a small non-coding RNA, Rfam:RF01764. The yjdF motif is found in many Firmicutes, including Bacillus subtilis. In most cases, it resides in potential 5' UTRs of homologs of the yjdF gene whose function is unknown. However, in Streptococcus thermophilus, a yjdF RNA motif is associated with an operon whose protein products synthesize nicotinamide adenine dinucleotide (NAD+). Also, the S. thermophilus yjdF RNA lacks typical yjdF motif consensus features downstream of and including the P4 stem. Thus, if yjdF RNAs are riboswitch aptamers, the S. thermophilus RNAs might sense a distinct compound that structurally resembles the ligand bound by other yjdF RNAs. On the ohter hand, perhaps these RNAs have an alternative solution forming a similar binding site, as is observed with some SAM riboswitches.


Pssm-ID: 402678  Cd Length: 132  Bit Score: 136.91  E-value: 1.52e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830048181   3 LTVYHDGQFFVGIITCKEKGKLYGARYIFGAEPSDEEVLIFVNGSMLAYFQQFAKCGVEVKEKqrPKNIKRIIRQAVKEV 82
Cdd:pfam11208   1 LTVFFDGPFWVGVFEREEGGKYKVARVTFGAEPKDYEVYEFILKNYSRLRFSPPVEAVERKEK--RINPKRLQREAKKEL 78
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1830048181  83 NVSRF-TKAQEAISLSYELHKQEKKVQSKEKREAEKQRRRLIKVQKAKQKHRGH 135
Cdd:pfam11208  79 RQRGIgTKAQQALKLQHEQRKLERKKRSKEQREAEKERRFQLKQQKRKEKHRGH 132
 
Name Accession Description Interval E-value
DUF2992 pfam11208
Protein of unknown function (DUF2992); This bacterial family of proteins has no known function. ...
3-135 1.52e-42

Protein of unknown function (DUF2992); This bacterial family of proteins has no known function. However, the cis-regulatory yjdF motif, just upstream from the gene encoding the proteins for this family, is a small non-coding RNA, Rfam:RF01764. The yjdF motif is found in many Firmicutes, including Bacillus subtilis. In most cases, it resides in potential 5' UTRs of homologs of the yjdF gene whose function is unknown. However, in Streptococcus thermophilus, a yjdF RNA motif is associated with an operon whose protein products synthesize nicotinamide adenine dinucleotide (NAD+). Also, the S. thermophilus yjdF RNA lacks typical yjdF motif consensus features downstream of and including the P4 stem. Thus, if yjdF RNAs are riboswitch aptamers, the S. thermophilus RNAs might sense a distinct compound that structurally resembles the ligand bound by other yjdF RNAs. On the ohter hand, perhaps these RNAs have an alternative solution forming a similar binding site, as is observed with some SAM riboswitches.


Pssm-ID: 402678  Cd Length: 132  Bit Score: 136.91  E-value: 1.52e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830048181   3 LTVYHDGQFFVGIITCKEKGKLYGARYIFGAEPSDEEVLIFVNGSMLAYFQQFAKCGVEVKEKqrPKNIKRIIRQAVKEV 82
Cdd:pfam11208   1 LTVFFDGPFWVGVFEREEGGKYKVARVTFGAEPKDYEVYEFILKNYSRLRFSPPVEAVERKEK--RINPKRLQREAKKEL 78
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1830048181  83 NVSRF-TKAQEAISLSYELHKQEKKVQSKEKREAEKQRRRLIKVQKAKQKHRGH 135
Cdd:pfam11208  79 RQRGIgTKAQQALKLQHEQRKLERKKRSKEQREAEKERRFQLKQQKRKEKHRGH 132
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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