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Conserved domains on  [gi|1817479091|gb|QIG41203|]
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sugar ABC transporter permease [Microbacterium sp. 4R-513]

Protein Classification

ABC transporter permease( domain architecture ID 10003058)

ABC transporter permease is the transmembrane subunit found in a periplasmic binding protein (PBP)-dependent ABC transport system, which may be involved in the transport of one or more from a variety of substrates such as monosaccharide sugars such as xylose, arabinose, and fructose

Gene Ontology:  GO:0140359|GO:0042626
PubMed:  18535149|17723295|25750732|24638992
TCDB:  3.A.1

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
AraH COG1172
Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component ...
 8-324 2.22e-70

Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component [Carbohydrate transport and metabolism];


:

Pssm-ID: 440785  Cd Length: 322  Bit Score: 221.52  E-value: 2.22e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091   8 LIPTLAALVLLFGMLIYAEIAYGRVFHAGTMSSLLVSFAPTIILAVGMTIVIVSGGIDLSVGAVVAFSSVAGVMLM-NIG 86
Cdd:COG1172    15 LLPELGLLLALVLLLVVFSILSPGFLSPGNLSNILRQAAILGILALGMTLVIITGGIDLSVGSVVALSGVVAALLLvALG 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091  87 VNGWLSMLLMILFGATFGLISGVMIQYFNVQPFIATLAMMFLARGLASILSttpvvaaDDSPILLLATDWKIIDGPKVnd 166
Cdd:COG1172    95 LPILLAILLALLVGALLGLLNGLLVAKLRIPPFIVTLGTMFIARGLALLLT-------GGRPISGLPDAFRALGQGSL-- 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091 167 FTITPGLLIAVLVVLGGMYFMHRTRMGRTVYAIGGNESSAQLMGLPVSRTRIWIYVVSGALAGLAAIVYTAEVGGkAQNV 246
Cdd:COG1172   166 LGIPVPVLIALVVALVAWFLLRRTRFGRYIYAVGGNEEAARLSGINVRRVKILAYVLSGLLAGLAGILLAARLGS-AQPN 244

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1817479091 247 TGIGWELDAIAAVVIGGTLLTGGYGYILGSIVGVFVIAALRLIITKDGtINPEYLTIITGAVLLVFVLLQRALTRRRA 324
Cdd:COG1172   245 AGSGYELDAIAAVVIGGTSLTGGRGSVLGTLLGALILGVLNNGLNLLG-VSSYWQQIVKGAIILLAVLLDRLRRRRRA 321
 
Name Accession Description Interval E-value
AraH COG1172
Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component ...
 8-324 2.22e-70

Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440785  Cd Length: 322  Bit Score: 221.52  E-value: 2.22e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091   8 LIPTLAALVLLFGMLIYAEIAYGRVFHAGTMSSLLVSFAPTIILAVGMTIVIVSGGIDLSVGAVVAFSSVAGVMLM-NIG 86
Cdd:COG1172    15 LLPELGLLLALVLLLVVFSILSPGFLSPGNLSNILRQAAILGILALGMTLVIITGGIDLSVGSVVALSGVVAALLLvALG 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091  87 VNGWLSMLLMILFGATFGLISGVMIQYFNVQPFIATLAMMFLARGLASILSttpvvaaDDSPILLLATDWKIIDGPKVnd 166
Cdd:COG1172    95 LPILLAILLALLVGALLGLLNGLLVAKLRIPPFIVTLGTMFIARGLALLLT-------GGRPISGLPDAFRALGQGSL-- 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091 167 FTITPGLLIAVLVVLGGMYFMHRTRMGRTVYAIGGNESSAQLMGLPVSRTRIWIYVVSGALAGLAAIVYTAEVGGkAQNV 246
Cdd:COG1172   166 LGIPVPVLIALVVALVAWFLLRRTRFGRYIYAVGGNEEAARLSGINVRRVKILAYVLSGLLAGLAGILLAARLGS-AQPN 244

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1817479091 247 TGIGWELDAIAAVVIGGTLLTGGYGYILGSIVGVFVIAALRLIITKDGtINPEYLTIITGAVLLVFVLLQRALTRRRA 324
Cdd:COG1172   245 AGSGYELDAIAAVVIGGTSLTGGRGSVLGTLLGALILGVLNNGLNLLG-VSSYWQQIVKGAIILLAVLLDRLRRRRRA 321
PRK11618 PRK11618
inner membrane ABC transporter permease protein YjfF; Provisional
 9-325 1.11e-63

inner membrane ABC transporter permease protein YjfF; Provisional


Pssm-ID: 183235 [Multi-domain]  Cd Length: 317  Bit Score: 204.03  E-value: 1.11e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091   9 IPTLAALVLLFGMLIYAEIAYGRVFHAGTMSSLLVSFAPTIILAVGMTIVIVSGGIDLSVGAVVAFSSV-AGVMLMNIGV 87
Cdd:PRK11618    6 LPLMITIGVFVLGYLFCLVQFPGFASTRVICNLLTDNAFLGIVAVGMTFVILSGGIDLSVGSVIAFTGVfLAKLIGDYGW 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091  88 NGWLSMLLMILFGATFGLISGVMIQYFNVQPFIATLAMMFLARGLASILSTTPVVAADDSPILLLATDWKIIDGPKvndf 167
Cdd:PRK11618   86 SPLLAFPLVLVMGAAFGAFMGALIHYLKLPAFIVTLAGMFLARGVSFLVSEESIPINHPFYDTLSSLAWKLPGGGR---- 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091 168 tITPGLLIAVLVVLGGMYFMHRTRMGRTVYAIGGNESSAQLMGLPVSRTRIWIYVVSGALAGLAAIVYTAEVGGkAQNVT 247
Cdd:PRK11618  162 -LSAMALIMLAVVAIGIFLAHRTRFGNNVYAIGGNATSANLMGIPVRRTTIRIYMLSGFLATLAGIVFSLYTSA-GYALA 239

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1817479091 248 GIGWELDAIAAVVIGGTLLTGGYGYILGSIVGVFVIAALRLIITKDGTINPEYLTIITGAVLLVFVLLQRALTRRRAS 325
Cdd:PRK11618  240 AVGVELDAIAAVVIGGTLLTGGVGTVLGTLFGVLIQGLIQTYITFDGTLSSWWTKIVIGILLFVFIALQRGLTVLAEN 317
TM_PBP1_transp_AraH_like cd06579
Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the ...
 45-316 3.94e-57

Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group also contains E. coli RbsC, AlsC, and MglC, which are TMs of other monosaccharide transporters, the ribose transporter, the D-allose transporter and the galactose transporter, respectively. The D-allose transporter may also be involved in low affinity ribose transport. These transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Proteins in this subgroup have a single TM which homodimerizes to generate the transmembrane pore.


Pssm-ID: 119321 [Multi-domain]  Cd Length: 263  Bit Score: 185.30  E-value: 3.94e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091  45 FAPTIILAVGMTIVIVSGGIDLSVGAVVAFSSVAGVMLM-NIGVNGWLSMLLMILFGATFGLISGVMIQYFNVQPFIATL 123
Cdd:cd06579     1 AAVLGILALGMTLVIITGGIDLSVGSVAALSAVVAALLLvNAGLPIPLAILAALAVGALIGLLNGLLVAYLRIPPFIVTL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091 124 AMMFLARGLASILSTTPVVAADDSPILLLATDWKIidgpkvndFTITPGLLIAVLVVLGGMYFMHRTRMGRTVYAIGGNE 203
Cdd:cd06579    81 GTMFILRGLALLITGGRPISGLPPLFSFFLGGGLI--------LGIPVPVLIALAVALVAWFLLRRTRFGRYLYAVGGNP 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091 204 SSAQLMGLPVSRTRIWIYVVSGALAGLAAIVYTAEVGGkAQNVTGIGWELDAIAAVVIGGTLLTGGYGYILGSIVGVFVI 283
Cdd:cd06579   153 EAARLSGINVRRVKILAYVLSGLLAGLAGILLAARLGS-AQPTAGNGYELDAIAAVVLGGTSLTGGRGSVLGTLLGALLL 231

                         250       260       270
                  ....*....|....*....|....*....|...
gi 1817479091 284 AALRLIITKDGtINPEYLTIITGAVLLVFVLLQ 316
Cdd:cd06579   232 GVLNNGLNLLG-VSSFWQQIVKGAILLLAVALD 263
GguB NF040906
sugar ABC transporter permease;
49-313 6.85e-35

sugar ABC transporter permease;


Pssm-ID: 468841 [Multi-domain]  Cd Length: 375  Bit Score: 130.27  E-value: 6.85e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091  49 IILAVGMTIVIVSGGIDLSVGAVVAF-SSVAGVMLMNIGVNGWLSMLLMILFGATFGLISGVMIQYFNVQPFIATLAMMF 127
Cdd:NF040906   43 LILAIGMLLVIIAGHIDLSVGSVVAFvGAVAAVLMVNWGMPWWLAVLLCLLVGALIGAWQGFWVAYVGIPAFIVTLAGML 122

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091 128 LARGLASILSTTPVVAADDSPILLLATDW--KIIDGPKVNDFTITPGLLIAVLVVLGGM--------------------- 184
Cdd:NF040906  123 VFRGLTLVVLGGQSIGPFPDGFQKISSGFlpDLFGGTGLHLLTLLLGVLAAAALVWSQLrgrrrrikyglevepmalfia 202

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091 185 -------------------------------------YFMHRTRMGRTVYAIGGNESSAQLMGLPVSRTRIWIYVVSGAL 227
Cdd:NF040906  203 klvliaaailfftyllasyrglpnvliilgvlilvysFVTNRTVIGRHIYAVGGNEKAAKLSGIKTKRVTFLVFVNMGVL 282

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091 228 AGLAAIVYTAEVGGkAQNVTGIGWELDAIAAVVIGGTLLTGGYGYILGSIVGVFVIAALRLIITKDGtINPEYLTIITGA 307
Cdd:NF040906  283 AALAGLVFAARLNS-ATPKAGNGFELDAIAACFIGGASASGGVGTVVGAIIGALVMGVLNNGMSILG-IGIDWQQVIKGL 360


                  ....*.
gi 1817479091 308 VLLVFV 313
Cdd:NF040906  361 VLLAAV 366
BPD_transp_2 pfam02653
Branched-chain amino acid transport system / permease component; This is a large family mainly ...
 38-313 6.85e-26

Branched-chain amino acid transport system / permease component; This is a large family mainly comprising high-affinity branched-chain amino acid transporter proteins such as E. coli LivH and LivM, both of which are form the LIV-I transport system. Also found with in this family are proteins from the galactose transport system permease and a ribose transport system.


Pssm-ID: 396977 [Multi-domain]  Cd Length: 269  Bit Score: 103.88  E-value: 6.85e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091  38 MSSLLVSFAPTIILAVGMTIVI-VSGGIDLSVGAVVAFSS-VAGVMLMNIGVNGWLSMLLMILFGATFGLISGVMIQYFN 115
Cdd:pfam02653   2 ILNILTLASIYAIAALGLTLIYgIAGVINLGHGGFMMLGAyVAAMLLNLLGPGLWLALPVGILVGAAVGLLIGILTLRLK 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091 116 VQPFIATLAMMFLARGLASILSTTPVVAADDSPillLATDWKIIDGPKVNdFTITPGLLIAVLVVLGGMYFMHRTRMGRT 195
Cdd:pfam02653  82 INEVIITLLLNLAALGLALFLVTGILGGEGGTS---GITGPSGFPGAFLS-FAFAFIFLLALLLVLALWLLLYRTKFGRA 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091 196 VYAIGGNESSAQLMGLPVSRTRIWIYVVSGALAGLAAIVYTAEVGGKAQNVTGIGWELDAIAAVVIggtlltGGYGYILG 275
Cdd:pfam02653 158 LRAVGENEEAARAAGINVKKLKLLTFVISGALAGLAGALLALYTGVVPPSNFGVGLGLDAIAAVVL------GGAGSPIG 231

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 1817479091 276 SIVGVFVIAALRLIITKDGTINPEYLTIITGAVLLVFV 313
Cdd:pfam02653 232 VVIGSLIIGLVQSLGLGALGSPPELSLLVLGALLILVL 269
 
Name Accession Description Interval E-value
AraH COG1172
Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component ...
 8-324 2.22e-70

Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440785  Cd Length: 322  Bit Score: 221.52  E-value: 2.22e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091   8 LIPTLAALVLLFGMLIYAEIAYGRVFHAGTMSSLLVSFAPTIILAVGMTIVIVSGGIDLSVGAVVAFSSVAGVMLM-NIG 86
Cdd:COG1172    15 LLPELGLLLALVLLLVVFSILSPGFLSPGNLSNILRQAAILGILALGMTLVIITGGIDLSVGSVVALSGVVAALLLvALG 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091  87 VNGWLSMLLMILFGATFGLISGVMIQYFNVQPFIATLAMMFLARGLASILSttpvvaaDDSPILLLATDWKIIDGPKVnd 166
Cdd:COG1172    95 LPILLAILLALLVGALLGLLNGLLVAKLRIPPFIVTLGTMFIARGLALLLT-------GGRPISGLPDAFRALGQGSL-- 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091 167 FTITPGLLIAVLVVLGGMYFMHRTRMGRTVYAIGGNESSAQLMGLPVSRTRIWIYVVSGALAGLAAIVYTAEVGGkAQNV 246
Cdd:COG1172   166 LGIPVPVLIALVVALVAWFLLRRTRFGRYIYAVGGNEEAARLSGINVRRVKILAYVLSGLLAGLAGILLAARLGS-AQPN 244

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1817479091 247 TGIGWELDAIAAVVIGGTLLTGGYGYILGSIVGVFVIAALRLIITKDGtINPEYLTIITGAVLLVFVLLQRALTRRRA 324
Cdd:COG1172   245 AGSGYELDAIAAVVIGGTSLTGGRGSVLGTLLGALILGVLNNGLNLLG-VSSYWQQIVKGAIILLAVLLDRLRRRRRA 321
PRK11618 PRK11618
inner membrane ABC transporter permease protein YjfF; Provisional
 9-325 1.11e-63

inner membrane ABC transporter permease protein YjfF; Provisional


Pssm-ID: 183235 [Multi-domain]  Cd Length: 317  Bit Score: 204.03  E-value: 1.11e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091   9 IPTLAALVLLFGMLIYAEIAYGRVFHAGTMSSLLVSFAPTIILAVGMTIVIVSGGIDLSVGAVVAFSSV-AGVMLMNIGV 87
Cdd:PRK11618    6 LPLMITIGVFVLGYLFCLVQFPGFASTRVICNLLTDNAFLGIVAVGMTFVILSGGIDLSVGSVIAFTGVfLAKLIGDYGW 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091  88 NGWLSMLLMILFGATFGLISGVMIQYFNVQPFIATLAMMFLARGLASILSTTPVVAADDSPILLLATDWKIIDGPKvndf 167
Cdd:PRK11618   86 SPLLAFPLVLVMGAAFGAFMGALIHYLKLPAFIVTLAGMFLARGVSFLVSEESIPINHPFYDTLSSLAWKLPGGGR---- 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091 168 tITPGLLIAVLVVLGGMYFMHRTRMGRTVYAIGGNESSAQLMGLPVSRTRIWIYVVSGALAGLAAIVYTAEVGGkAQNVT 247
Cdd:PRK11618  162 -LSAMALIMLAVVAIGIFLAHRTRFGNNVYAIGGNATSANLMGIPVRRTTIRIYMLSGFLATLAGIVFSLYTSA-GYALA 239

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1817479091 248 GIGWELDAIAAVVIGGTLLTGGYGYILGSIVGVFVIAALRLIITKDGTINPEYLTIITGAVLLVFVLLQRALTRRRAS 325
Cdd:PRK11618  240 AVGVELDAIAAVVIGGTLLTGGVGTVLGTLFGVLIQGLIQTYITFDGTLSSWWTKIVIGILLFVFIALQRGLTVLAEN 317
TM_PBP1_transp_AraH_like cd06579
Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the ...
 45-316 3.94e-57

Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group also contains E. coli RbsC, AlsC, and MglC, which are TMs of other monosaccharide transporters, the ribose transporter, the D-allose transporter and the galactose transporter, respectively. The D-allose transporter may also be involved in low affinity ribose transport. These transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Proteins in this subgroup have a single TM which homodimerizes to generate the transmembrane pore.


Pssm-ID: 119321 [Multi-domain]  Cd Length: 263  Bit Score: 185.30  E-value: 3.94e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091  45 FAPTIILAVGMTIVIVSGGIDLSVGAVVAFSSVAGVMLM-NIGVNGWLSMLLMILFGATFGLISGVMIQYFNVQPFIATL 123
Cdd:cd06579     1 AAVLGILALGMTLVIITGGIDLSVGSVAALSAVVAALLLvNAGLPIPLAILAALAVGALIGLLNGLLVAYLRIPPFIVTL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091 124 AMMFLARGLASILSTTPVVAADDSPILLLATDWKIidgpkvndFTITPGLLIAVLVVLGGMYFMHRTRMGRTVYAIGGNE 203
Cdd:cd06579    81 GTMFILRGLALLITGGRPISGLPPLFSFFLGGGLI--------LGIPVPVLIALAVALVAWFLLRRTRFGRYLYAVGGNP 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091 204 SSAQLMGLPVSRTRIWIYVVSGALAGLAAIVYTAEVGGkAQNVTGIGWELDAIAAVVIGGTLLTGGYGYILGSIVGVFVI 283
Cdd:cd06579   153 EAARLSGINVRRVKILAYVLSGLLAGLAGILLAARLGS-AQPTAGNGYELDAIAAVVLGGTSLTGGRGSVLGTLLGALLL 231

                         250       260       270
                  ....*....|....*....|....*....|...
gi 1817479091 284 AALRLIITKDGtINPEYLTIITGAVLLVFVLLQ 316
Cdd:cd06579   232 GVLNNGLNLLG-VSSFWQQIVKGAILLLAVALD 263
COG4158 COG4158
Predicted ABC-type sugar transport system, permease component [General function prediction ...
 3-324 2.35e-44

Predicted ABC-type sugar transport system, permease component [General function prediction only];


Pssm-ID: 443324  Cd Length: 334  Bit Score: 154.32  E-value: 2.35e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091   3 ERSQTLIPTLAALVLLFGMLIYAEIAYGRVFHAGTMSSLLVSFAPTIILAVGMTIVIVSGGIDLSVGAVVAFSSVAGVML 82
Cdd:COG4158    21 FRLRSLLQAVGMLPVLILLCIGFELLTPNFLTVQNLSNIARQASINIVLAAGMTFVILTGGIDLSVGSILAASAVVAVLV 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091  83 MNIGVNGWLSMLLMILFGATFGLISGVMIQYFNVQPFIATLAMMFLARGLASILSTTPVVAADDSPILLLATdwkiidgp 162
Cdd:COG4158   101 SLLPGLGLLGIPAALLVGLLFGLINGLLIAFLKLPPFIVTLGSLTALRGAARLLANGTTVFNPDLPFAWIGN-------- 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091 163 kvNDFTITPGL-LIAVLVVLGGMYFMHRTRMGRTVYAIGGNESSAQLMGLPVSRTRIWIYVVSGALAGLAAIVYTAEVGG 241
Cdd:COG4158   173 --GYLLGIPWLvVIALAVVLASWFILRRTVLGVHIYAVGGNAQAARLTGIKVWRVLLFVYAVSGLLAGLGGVMSAARLYA 250

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091 242 KAQNVTGIGWELDAIAAVVIGGTLLTGGYGYILGSIVGVFVIAALR--LIITkdgTINPEYLTIITGAVLLVFVLLQRAL 319
Cdd:COG4158   251 ANGLQLGQGYELDAIAAVILGGTSFVGGIGSIWGTLIGALIIAVLNngLILL---GVSDFWQFIIKGLVIIIAVALDRYR 327


                  ....*
gi 1817479091 320 TRRRA 324
Cdd:COG4158   328 QRGSA 332
XylH COG4214
ABC-type xylose transport system, permease component [Carbohydrate transport and metabolism];
10-324 3.40e-42

ABC-type xylose transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 443360 [Multi-domain]  Cd Length: 393  Bit Score: 150.27  E-value: 3.40e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091  10 PTLAALVLLfgMLIYAEIAYGRVFHAGTMSSLLVSFAPTIILAVGMTIVIVSGGIDLSVGAVVAFSS-VAGVMLMNIGVN 88
Cdd:COG4214    26 GMIIALVVI--WIVFQILTGGTFLTPRNLSNLLLQNSYIGILAIGMVLVILLGHIDLSVGSVSGFVGaVAAVLMVNWGLP 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091  89 GWLSMLLMILFGATFGLISGVMIQYFNVQPFIATLAMMFLARGLASILSTTPVVAADDSPILLLATDWkiidgpkVNDFT 168
Cdd:COG4214   104 WWLAILAALLVGALIGAWQGFWVAYVGIPSFIVTLAGMLAFRGLTLLVLGGGTIAPFDPTFQAIGNGF-------LPDIL 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091 169 ITPGLLIAVLVVLG--------------------------------------------------------------GMYF 186
Cdd:COG4214   177 GTLSWVLGAVAVAAyvalqlrsrrrrrryglpveplwlfvlklallavlilgavyllnsyrgipivvlillvlvvvYTFV 256

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091 187 MHRTRMGRTVYAIGGNESSAQLMGLPVSRTRIWIYVVSGALAGLAAIVYTAEVGGkAQNVTGIGWELDAIAAVVIGGTLL 266
Cdd:COG4214   257 LTRTVFGRHIYAVGGNPEAARLSGINVRRVTFSVFVNMGVLAALAGIVFAARLNS-ATPSAGTGFELDAIAAAVIGGTSL 335

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1817479091 267 TGGYGYILGSIVGVFVIAALrliitKDG----TINPEYLTIITGAVLLVFVLLQrALTRRRA 324
Cdd:COG4214   336 FGGVGTVYGAVIGALVMGSL-----NNGmsllGVDSDWQQIVKGLVLLLAVAFD-VLSRRRR 391
rbsC PRK09512
ribose ABC transporter permease protein; Reviewed
 50-315 5.67e-38

ribose ABC transporter permease protein; Reviewed


Pssm-ID: 181922 [Multi-domain]  Cd Length: 320  Bit Score: 137.54  E-value: 5.67e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091  50 ILAVGMTIVIVSGGIDLSVGAVVAFSSVAGVMLMNIGVNGWLSMLLMILFGATFGLISGVMIQYFNVQPFIATLAMMFLA 129
Cdd:PRK09512   57 IMAVGMTLVILTSGIDLSVGSLLALTGAVAASIVGIEVNALVAVPAALALGAAIGAVTGVIVAKGKVQAFIATLVMMLLL 136

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091 130 RGLAsilsttpVVAADDSPILLLATD------WKIIDGPkvndFTITPGLLIAVLVVLGGMYFMHRTRMGRTVYAIGGNE 203
Cdd:PRK09512  137 RGVT-------MVYTDGSPINTGFTDnadlfgWFGIGRP----LGIPTPVWIMAIVFLAAWYMLHHTRLGRYIYALGGNE 205

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091 204 SSAQLMGLPVSRTRIWIYVVSGALAGLAAIVYTAEVgGKAQNVTGIGWELDAIAAVVIGGTLLTGGYGYILGSIVGVFVI 283
Cdd:PRK09512  206 AATRLSGINVNKVKIIVYALCGLLAALAGIIEVARL-SSAQPTAGTGYELDAIAAVVLGGTSLAGGKGRIVGTLIGALIL 284

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 1817479091 284 A----ALRLIitkdgTINPEYLTIITGAVLLVFVLL 315
Cdd:PRK09512  285 GflnnGLNLL-----GVSSYYQMIVKAVVILLAVLV 315
GguB NF040906
sugar ABC transporter permease;
49-313 6.85e-35

sugar ABC transporter permease;


Pssm-ID: 468841 [Multi-domain]  Cd Length: 375  Bit Score: 130.27  E-value: 6.85e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091  49 IILAVGMTIVIVSGGIDLSVGAVVAF-SSVAGVMLMNIGVNGWLSMLLMILFGATFGLISGVMIQYFNVQPFIATLAMMF 127
Cdd:NF040906   43 LILAIGMLLVIIAGHIDLSVGSVVAFvGAVAAVLMVNWGMPWWLAVLLCLLVGALIGAWQGFWVAYVGIPAFIVTLAGML 122

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091 128 LARGLASILSTTPVVAADDSPILLLATDW--KIIDGPKVNDFTITPGLLIAVLVVLGGM--------------------- 184
Cdd:NF040906  123 VFRGLTLVVLGGQSIGPFPDGFQKISSGFlpDLFGGTGLHLLTLLLGVLAAAALVWSQLrgrrrrikyglevepmalfia 202

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091 185 -------------------------------------YFMHRTRMGRTVYAIGGNESSAQLMGLPVSRTRIWIYVVSGAL 227
Cdd:NF040906  203 klvliaaailfftyllasyrglpnvliilgvlilvysFVTNRTVIGRHIYAVGGNEKAAKLSGIKTKRVTFLVFVNMGVL 282

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091 228 AGLAAIVYTAEVGGkAQNVTGIGWELDAIAAVVIGGTLLTGGYGYILGSIVGVFVIAALRLIITKDGtINPEYLTIITGA 307
Cdd:NF040906  283 AALAGLVFAARLNS-ATPKAGNGFELDAIAACFIGGASASGGVGTVVGAIIGALVMGVLNNGMSILG-IGIDWQQVIKGL 360


                  ....*.
gi 1817479091 308 VLLVFV 313
Cdd:NF040906  361 VLLAAV 366
araH PRK11285
L-arabinose transporter permease protein; Provisional
 38-325 1.47e-32

L-arabinose transporter permease protein; Provisional


Pssm-ID: 183076 [Multi-domain]  Cd Length: 333  Bit Score: 123.25  E-value: 1.47e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091  38 MSSLLVSFAPTIILAVGMTIVIVSGGIDLSVGAVVAFSSVAGVMLMNIGVNGWLSMLLMILFGATFGLISGVMIQYFNVQ 117
Cdd:PRK11285   56 MKGLGLAISMIGMVACTMLFCLASGDFDLSVASVVAFAGVVTAVVINATESLWLGVAAGLLLGAAVGLVNGFVIARLKIN 135

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091 118 PFIATLAMMFLARGLASILSTTPVV-AADDSPILLLATDWKIIDGPKVndftitpgLLIAVLVVLGgmYFMHRTRMGRTV 196
Cdd:PRK11285  136 ALITTLATMQIVRGLAYIISDGKAVgISDERFFALGYANFFGVPAPIW--------LTVACFVVFG--FLLNKTTFGRNT 205

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091 197 YAIGGNESSAQLMGLPVSRTRIWIYVVSGALAGLAAIVYTAEVgGKAQNVTGIGWELDAIAAVVIGGTLLTGGYGYILGS 276
Cdd:PRK11285  206 LAIGGNEEAARLAGVPVVRTKIIIFVLQGLVSALAGVILASRM-TSGQPMTSIGFELIVISACVLGGVSLKGGIAKISGV 284

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1817479091 277 IVGVFVIA----ALRLIitkdgTINPEYLTIITGAVLLVFVLLQRALTRRRAS 325
Cdd:PRK11285  285 VAGVLILGtvenAMNLL-----NISPFYQYVVRGLILLAAVLFDRYKQRAKRT 332
mglC PRK09478
galactose/methyl galactoside ABC transporter permease MglC;
49-315 2.35e-27

galactose/methyl galactoside ABC transporter permease MglC;


Pssm-ID: 181892 [Multi-domain]  Cd Length: 336  Bit Score: 109.39  E-value: 2.35e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091  49 IILAVGMTIVIVSGGIDLSVGAVVAFSSVAGVMLMNIGVNGW------------LSMLLMILFGATFGLISGVMIQYFNV 116
Cdd:PRK09478   53 IIIALGVAGLIVTQGTDLSAGRQVGLAAVVAATLLQSMDNANkvfpelatmpiaLVILIVCAIGAVIGLINGLIIAYLNV 132

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091 117 QPFIATLAMMFLARGLASiLSTTPVVAaddSPILLLATDWKII--DGPKVNDFTITPGLLIAVLVVLGGMYFMHRTRMGR 194
Cdd:PRK09478  133 TPFIATLGTMIIVYGINS-LYYDFVGA---SPISGFDSGFSTFaqGFVALGSFRLSYITFYALIAVAFVWVLWNKTRFGK 208

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091 195 TVYAIGGNESSAQLMGLPVSRTRIWIYVVSGALAGLAAIVYTAEVGGkAQNVTGIGWELDAIAAVVIGGTLLTGGYGYIL 274
Cdd:PRK09478  209 NIFAIGGNPEAAKVSGVNVPLNLLMIYALSGVFYAFGGMLEAGRIGS-ATNNLGFMYELDAIAACVVGGVSFSGGVGTVI 287

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 1817479091 275 GSIVGVFVIAALRLIITKDGtINPEYLTIITGAVLLVFVLL 315
Cdd:PRK09478  288 GVVTGVIIFTVINYGLTYIG-VNPYWQYIIKGAIIIFAVAL 327
PRK09699 PRK09699
D-allose ABC transporter permease;
15-321 1.32e-26

D-allose ABC transporter permease;


Pssm-ID: 182035 [Multi-domain]  Cd Length: 312  Bit Score: 106.78  E-value: 1.32e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091  15 LVLLFGMLIYAEIAYGRVFHAGTMSSLLVSFAPTIILAVGMTIVIVSGGIDLSVGAVVAFSSVAGVMLMNIGVNGWLSML 94
Cdd:PRK09699   16 FILAIIVAIFGSLSPEYFLTTNNITQIFVQSSVTVLIGMGEFFAILVAGIDLSVGAILALSGMVTAKLMLAGVDPFLAAL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091  95 L-MILFGATFGLISGVMIQYFNVQPFIATLAMMFLARGLASILSttpvvaaDDSPILLLATDWKIIDGPKVndFTITPGL 173
Cdd:PRK09699   96 IgGVLVGGALGAINGCLVNWTGLHPFIITLGTNAIFRGITLVIS-------DANSVYGFSFDFVNFFAASV--IGIPVPV 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091 174 LIAVLVVLGGMYFMHRTRMGRTVYAIGGNESSAQLMGLPVSRTRIWIYVVSGALAGLAAIVYTAEVGGkAQNVTGIGWEL 253
Cdd:PRK09699  167 IFSLIVALILWFLTTRMRLGRNIYALGGNKNSAFYSGIDVKFHILVVFIISGVCAGLAGVVSTARLGA-AEPLAGMGFET 245

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1817479091 254 DAIAAVVIGGTLLTGGYGYILGSIVGVFVIAALRLIITKDGtINPEYLTIITGAVLLVFVLLQRALTR 321
Cdd:PRK09699  246 YAIASAIIGGTSFFGGKGRIFSVVIGGLIIGTINNGLNILQ-VQTYYQLVVMGGLIIAAVALDRLISK 312
PRK15432 PRK15432
autoinducer 2 ABC transporter permease LsrC; Provisional
 12-281 2.77e-26

autoinducer 2 ABC transporter permease LsrC; Provisional


Pssm-ID: 185330 [Multi-domain]  Cd Length: 344  Bit Score: 106.35  E-value: 2.77e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091  12 LAALVLLFGMLIYAEIAYgrvFHAGTMSSLLVSFAPTIILAVGMTIVIVSGGIDLSVGAVVAFSSVAGVMLMNIGVNGWL 91
Cdd:PRK15432   14 LLAIVLLFVLLGFLDRQY---LSLQTLTMVFSSAQILILLAIGATLVMLTRNIDVSVGSITGLCAVLVGMLLNAGYSLPV 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091  92 SMLLMILFGATFGLISGVMIQYFNVQPFIATLAMMFLARGLASILSttpvvaaDDSPILLLATDWKIIDGPKVndFTITP 171
Cdd:PRK15432   91 ACLATLLLGLLAGFFNGVLVAWLRIPAIVATLGTLGLYRGIMLLWT-------GGKWIEGLPAELKQLSAPIL--LGISP 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091 172 GLLIAVLVVLGGMYFMHRTRMGRTVYAIGGNESSAQLMGLPVSRTRIWIYVVSGALAGLAAIVYTAEVgGKAQNVTGIGW 251
Cdd:PRK15432  162 IGWLTLILILAMAWLLAKTAFGRSFYATGDNLQGARQLGVRTEAIRIVAFSLNGCMAALAGIVFASQI-GFIPNQTGTGL 240

                         250       260       270
                  ....*....|....*....|....*....|
gi 1817479091 252 ELDAIAAVVIGGTLLTGGYGYILGSIVGVF 281
Cdd:PRK15432  241 EMKAIAACVLGGISLLGGSGTIIGAVLGAY 270
BPD_transp_2 pfam02653
Branched-chain amino acid transport system / permease component; This is a large family mainly ...
 38-313 6.85e-26

Branched-chain amino acid transport system / permease component; This is a large family mainly comprising high-affinity branched-chain amino acid transporter proteins such as E. coli LivH and LivM, both of which are form the LIV-I transport system. Also found with in this family are proteins from the galactose transport system permease and a ribose transport system.


Pssm-ID: 396977 [Multi-domain]  Cd Length: 269  Bit Score: 103.88  E-value: 6.85e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091  38 MSSLLVSFAPTIILAVGMTIVI-VSGGIDLSVGAVVAFSS-VAGVMLMNIGVNGWLSMLLMILFGATFGLISGVMIQYFN 115
Cdd:pfam02653   2 ILNILTLASIYAIAALGLTLIYgIAGVINLGHGGFMMLGAyVAAMLLNLLGPGLWLALPVGILVGAAVGLLIGILTLRLK 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091 116 VQPFIATLAMMFLARGLASILSTTPVVAADDSPillLATDWKIIDGPKVNdFTITPGLLIAVLVVLGGMYFMHRTRMGRT 195
Cdd:pfam02653  82 INEVIITLLLNLAALGLALFLVTGILGGEGGTS---GITGPSGFPGAFLS-FAFAFIFLLALLLVLALWLLLYRTKFGRA 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091 196 VYAIGGNESSAQLMGLPVSRTRIWIYVVSGALAGLAAIVYTAEVGGKAQNVTGIGWELDAIAAVVIggtlltGGYGYILG 275
Cdd:pfam02653 158 LRAVGENEEAARAAGINVKKLKLLTFVISGALAGLAGALLALYTGVVPPSNFGVGLGLDAIAAVVL------GGAGSPIG 231

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 1817479091 276 SIVGVFVIAALRLIITKDGTINPEYLTIITGAVLLVFV 313
Cdd:pfam02653 232 VVIGSLIIGLVQSLGLGALGSPPELSLLVLGALLILVL 269
TM_PBP1_branched-chain-AA_like cd06574
Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette ...
 49-313 3.26e-20

Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of monosaccharides including ribose, galactose, and arabinose. These transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. This group includes Escherichia coli LivM and LivH, two TMs which heterodimerize to form the translocation pathway of the E. coli branched-chain AA LIV-1/LS transporter. This transporter is comprised of two TMs (LivM and LivH), two ABCs (LivG and LivF), and one of two alternative PBPs, LivJ (LIV-BP) and LivK (LS-BP). In addition to transporting branched-chain AAs including leucine, isoleucine and valine, the E. coli LIV-1/LS transporter is involved in the uptake of the aromatic AA, phenylalanine. Included in this group are proteins from transport systems that contain a single TM which homodimerizes to generate the transmembrane pore; for example E. coli RbsC, AlsC, and MglC, the TMs of the high affinity ribose transporter, the D-allose transporter and the galactose transporter, respectively. The D-allose transporter may also to be involved in low affinity ribose transport.


Pssm-ID: 119320 [Multi-domain]  Cd Length: 266  Bit Score: 88.10  E-value: 3.26e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091  49 IILAVGMTIVI-VSGGIDLSVGAVVAFSSVAGVMLMNIGVNGWLSMLLMILFGATFGLISGVMIQYFNVQPFIATLAMMF 127
Cdd:cd06574     5 AILALGVYIVFrILGFPDLTVDGSFPLGAAVAAILIVAGYNPWLALIAAILAGAAAGLVTGFLHTRLKINGLLAGILIMI 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091 128 LARGLASILSTTPVVAADDSPILLLATDWKIIDGPKVndftITPGLLIAVLVVLGGMYFMHRTRMGRTVYAIGGNESSAQ 207
Cdd:cd06574    85 GLYSINLRIMGGPNIPLGTRDTLLGLLLLFGISGTLS----IPVVLLLIVLLVLFLVIWFLRTKLGLAMRATGDNPDMAR 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091 208 LMGLPVSRTRIWIYVVSGALAGLAAIVYtAEVGGKAQNVTGIGWELDAIAAVVI------GGTLLTGGYGYILGSIVGVF 281
Cdd:cd06574   161 SLGINVDRTRILGLVISNALAALGGALY-AQYQGFADVNMGIGTGVIGLAAVIIggaivgRRTIKASILGVIIGAILYRI 239

                         250       260       270
                  ....*....|....*....|....*....|..
gi 1817479091 282 VIAALRLIitkdgTINPEYLTIITGAVLLVFV 313
Cdd:cd06574   240 ALALALGS-----GLIPSDLKLITAGVIVLVL 266
PRK15038 PRK15038
autoinducer 2 ABC transporter permease LsrD;
50-314 3.13e-19

autoinducer 2 ABC transporter permease LsrD;


Pssm-ID: 184998  Cd Length: 330  Bit Score: 86.81  E-value: 3.13e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091  50 ILAVGMTIVIVSGGIDLSVGAVVAFSSVAGVMLMNIGVNGWLSMLLMILFGATFGLISGVMIQYFNVQPFIATLAMMFLA 129
Cdd:PRK15038   47 IVALPLTMVIVSGGIDISFGSTIGLCAIALGVLFQSGVPMPLAILLTLLLGALCGLINAGLIIYTGVNPLVITLGTLYLF 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091 130 RGLASILSTtpvvaaddspiLLLATDWKIIDG--PKVNDFT------ITPGLLIAVLVVLGGMYFMHRTRMGRTVYAIGG 201
Cdd:PRK15038  127 GGSALLLSG-----------MAGATGYEGIGGfpMAFTDFAnldvlgLPVPLIIFLICLLVFWLLMHRTHAGRNVFLIGQ 195

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091 202 NESSAQLMGLPVSRTRIWIYVVSGALAGLAAIVYTAEVgGKAQNVTGIGWELDAIAAVVIGGTLLTGGYGYILGSIVGVF 281
Cdd:PRK15038  196 SPRVALYSAIPVNRTLCALYAMTGLASAIAAVLLVSYF-GSARSDLGASFLMPAITAVVLGGANIYGGSGSIIGTALAVL 274

                         250       260       270
                  ....*....|....*....|....*....|...
gi 1817479091 282 VIAALRLIITKDGTINpEYLTIITGAVLLVFVL 314
Cdd:PRK15038  275 LVGYLQQGLQMAGVPN-QISSALSGALLIVVVV 306
NupQ COG1079
ABC-type guanosine uptake system NupNOPQ, permease subunit NupQ [Nucleotide transport and ...
 35-260 4.53e-15

ABC-type guanosine uptake system NupNOPQ, permease subunit NupQ [Nucleotide transport and metabolism];


Pssm-ID: 440697 [Multi-domain]  Cd Length: 309  Bit Score: 74.34  E-value: 4.53e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091  35 AGTMSSLLVSFAPTIILAVGMTIVIVSGGIDLSVGAVVAFSSVAGVMLMNIGVNGWLSMLLMILFGATFGLISGVMIQYF 114
Cdd:COG1079     8 ASLLAATLRAATPLLLAALGGLFSERAGVLNIGLEGMMLMGAFAGFAVAYLTGSPWLGLLAAALAGALLALLHAFLTITL 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091 115 NVQPFIATLAMMFLARGLASILSTTPVVAADDSPILLLATDWKI-------IDGPKVndFTITPGLLIAVLVVLGGMYFM 187
Cdd:COG1079    88 RANQIVSGLALNLLALGLTAFLGRLLFGQGGQTPSIPGLPPIPIpglsdipVLGPLL--FGQSPLVYLALLLVPLVWWVL 165

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1817479091 188 HRTRMGRTVYAIGGNESSAQLMGLPVSRTRIWIYVVSGALAGLAAIVYT-AEVGGKAQNVT-GIGWEldAIAAVV 260
Cdd:COG1079   166 YRTRFGLRLRAVGENPAAADALGINVYRIRYLAVLIGGALAGLGGAYLSlGYVGSFTEGMTaGRGFI--ALAAVI 238
NupP COG4603
ABC-type guanosine uptake system NupNOPQ, permease component NupP [Nucleotide transport and ...
 3-323 5.76e-13

ABC-type guanosine uptake system NupNOPQ, permease component NupP [Nucleotide transport and metabolism];


Pssm-ID: 443653 [Multi-domain]  Cd Length: 356  Bit Score: 68.61  E-value: 5.76e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091   3 ERSQTLIPTLAALV--LLFGMLI-----------YAEIAYGRVFHAGTMSSLLVSFAPTIILAVGMTIVIVSG----GID 65
Cdd:COG4603    11 LRLRSLLIPLLAVLlaLLVGALLillaganpleaYSALFQGAFGSPYGLGETLVKATPLILTGLAVAVAFRAGlfniGAE 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091  66 --LSVGAVVAfssvAGVMLMNIGVNGWLSMLLMILFGATFG----LISGVMIQYFNVQPFIATLAMMFLARGLASILSTT 139
Cdd:COG4603    91 gqLYLGALAA----AAVGLALPGLPGPLHLPLALLAGALAGalwaAIPGLLKARFGVNEVITTLMLNYIALYLVNYLVRG 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091 140 PVVAADDS-----PILLLATDWKIIDGPKVNdftitPGLLIAVLVVLGGMYFMHRTRMGRTVYAIGGNESSAQLMGLPVS 214
Cdd:COG4603   167 PLRDPGSGfpqtpPIPESARLPRLLPGTRLH-----LGLLIALLAAVLVWVLLNRTTLGYELRAVGLNPRAARYAGINVK 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091 215 RTRIWIYVVSGALAGLAAIVYTAEVGGKAQN--VTGIGWelDAIAAVVIggtlltgGYGYILGSIVGVFVIAALR---LI 289
Cdd:COG4603   242 RLIVLAMLISGALAGLAGAVEVLGVQGRLTPgfSPGYGF--TGIAVALL-------GRNNPLGIILAALLFGALYvggDA 312

                         330       340       350
                  ....*....|....*....|....*....|....
gi 1817479091 290 ITKDGTINPEYLTIITGAVLLvFVLLQRALTRRR 323
Cdd:COG4603   313 MQRALGVPSEIVDVIQGLIIL-FVLAADFLIRYR 345
TM_PBP1_transp_TpRbsC_like cd06580
Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. ...
 45-311 7.66e-12

Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters, which are mainly involved in the uptake of branched-chain amino acids (AAs) or in the uptake of monosaccharides including ribose, galactose, and arabinose, and which generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction.


Pssm-ID: 119322 [Multi-domain]  Cd Length: 234  Bit Score: 64.00  E-value: 7.66e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091  45 FAPTIILAVGMTIVIVSGGIDLS------VGAVVAFSsVAGVMLMNIGVNGWLSMLLMILFGATFGLISGVMIQYFNVQP 118
Cdd:cd06580     1 ATPLILAALGVAISFRAGVFNIGlegqmlLGAFAAAL-VALYLGLPATGSLPLGLLAAALAGALWALLPALLKAKLGVNE 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091 119 FIATLAMMFLARGLASILsttpvvaaddspilllatdwkiidgpkvndftitpgLLIAVLVVLGGMYFMHRTRMGRTVYA 198
Cdd:cd06580    80 VISGLMLNYIALGLTSYL------------------------------------LLLALLLVILVWLLLYRTRFGLRLRA 123

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091 199 IGGNESSAQLMGLPVSRTRIWIYVVSGALAGLAAIVYTAEVGGKAQNVTGIGWELDAIAAVVIggtlltgGYGYILGSIV 278
Cdd:cd06580   124 VGENPRAARYAGINVKRVRLLAMLISGALAGLAGAYLVLGVQGRFTEGMSAGYGFIAIAVALL-------GRWNPLGILL 196

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 1817479091 279 GVFVIAALR---LIITKDGTINPEYLTIITGAVLLV 311
Cdd:cd06580   197 AALLFGALEaggIALQRSGGVPSELVQVLPGIIVLF 232
LivM COG4177
ABC-type branched-chain amino acid transport system, permease component [Amino acid transport ...
 40-315 1.59e-10

ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 443336 [Multi-domain]  Cd Length: 285  Bit Score: 60.87  E-value: 1.59e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091  40 SLLVSFAPTIILAVGMTIVIVSGGIdLSVGAVVAFSS---VAGVMLMNIGVNGWLSMLLMILFGATFGLISGVMI----- 111
Cdd:COG4177     6 SLLTLILIYAILALGLNLLLGYTGL-LSLGHAAFFGIgayAAALLTTHLGLPFWLALLLAGLVAALLGLLIGLPAlrlrg 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091 112 QYFNvqpfIATLAMMFLARGLAsiLSTTPVVAADDSpiLLLATDWKIIDGPKVNDFTITPGLLIAVLVVLGGMYFMHRTR 191
Cdd:COG4177    85 DYLA----IATLAFAEIVRLLA--LNLESLTGGADG--LSGIPRPTLFGLDLGSPLAFYYLVLALLVLVLLLLRRLVRSR 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091 192 MGRTVYAIGGNESSAQLMGLPVSRTRIWIYVVSGALAGLAAIVYTAEVGGKAQNVTGIGWELDAIAAVVIggtlltGGYG 271
Cdd:COG4177   157 FGRALRAIRENEIAAEALGINVTRYKLLAFVLSAALAGLAGALYAHYVGFVSPESFSFLLSIEILLMVVL------GGLG 230

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 1817479091 272 YILGSIVGVFVIAALRLIItkdgTINPEYLTIITGAVLLVFVLL 315
Cdd:COG4177   231 SLLGPVLGAVLLVLLPELL----RSLPEYRLLIFGLLLILVVLF 270
TM_PBP1_LivM_like cd06581
Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two ...
 49-315 3.84e-10

Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of branched-chain amino acids (AAs). These types of transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. E. coli LivM forms a heterodimer with another TM, LivH, to generate the transmembrane pore. LivH is not included in this subgroup. The LIV-1/LS transporter is comprised of two TMs (LivM and LivH), two ABCs (LivG and LivF), and one of two alternative PBPs, LivJ (LIV-BP) or LivK (LS-BP). In addition to transporting branched-chain AAs including leucine, isoleucine and valine, the E. coli LIV-1/LS transporter is involved in the uptake of the aromatic AA, phenylalanine.


Pssm-ID: 119323 [Multi-domain]  Cd Length: 268  Bit Score: 59.38  E-value: 3.84e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091  49 IILAVGMTIVIVSGGIdLSVGAVVAFSS---VAGVMLMNIGVNGWLSMLLMILFGATFGLISGVMI-----QYFnvqpFI 120
Cdd:cd06581     5 AILALGLNLLLGYAGQ-LSLGHAAFFGIgayTAALLATRLGLPFWLALLAAGLVAALVGLLLGLPAlrlrgVYF----AI 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091 121 ATLAMMFLARGLAsiLSTTPVVAADD--SPILLLATDWKIIDGPKVNDFTItpglLIAVLVVLGGMYFMHRTRMGRTVYA 198
Cdd:cd06581    80 ATLAFAEIVRLLA--LNWSSLTGGSNglSGIPPPLLGGLLLSSPLAFYYLV----LAVLLLVLLLLRRLVRSPFGRALRA 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091 199 IGGNESSAQLMGLPVSRTRIWIYVVSGALAGLAAIVYTAEVGGKAQNVTGIGWELDAIAAVVIggtlltGGYGYILGSIV 278
Cdd:cd06581   154 IRENEVAAEALGINVTRYKLLAFALSAALAGLAGALYAHYLGFVSPESFGFALSIELLLMVVL------GGLGSLLGPVL 227

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 1817479091 279 GVFVIAALRLIITkdgTINPEYLTIITGAVLLVFVLL 315
Cdd:cd06581   228 GAALLVLLPELLR---SLGPGLRLLVFGLLLILVVLF 261
TM_PBP1_LivH_like cd06582
Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two ...
 50-261 3.23e-09

Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of branched-chain amino acids (AAs). These types of transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. E. coli LivH forms a heterodimer with another TM, LivM, to generate the transmembrane pore. LivM is not included in this subgroup. The LIV-1/LS transporter is comprised of two TMs (LivM and LivH), two ABCs (LivG and LivF), and one of two alternative PBPs, LivJ (LIV-BP) or LivK (LS-BP). In addition to transporting branched-chain AAs including leucine, isoleucine and valine, the E. coli LIV-1/LS transporter is involved in the uptake of the aromatic AA, phenylalanine.


Pssm-ID: 119324 [Multi-domain]  Cd Length: 272  Bit Score: 56.67  E-value: 3.23e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091  50 ILAVGMTIVI-VSGGIDLSVGAVVAFSSVAGVMLMNI-GVNGWLSMLLMILFGATFG-LISGVMIQYF----NVQPFIAT 122
Cdd:cd06582    10 LIALGLTLIFgVTGVINFAHGEFYMLGAYVAYTLLVAlGLPFWLALLLALLVAALLGvLLERLVLRPLrgapLLTLLITF 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091 123 LAMMFLARGLASILSTTPVVAadDSPILLLATDWKIIDGPKVNDFTItpglLIAVLVVLGGMYFMHRTRMGRTVYAIGGN 202
Cdd:cd06582    90 GGLLILLQGLLLIFGGDPRVP--PPPLLSGSVELGGVTIPPYRLFII----AVALVLLAALYLFLRRTRLGRAIRAVAQN 163

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1817479091 203 ESSAQLMGLPVSRTRIWIYVVSGALAGLAAIVYTAEVGgkAQNVTGIGWELDAIAAVVI 261
Cdd:cd06582   164 PEAARLLGINVRRVFALTFALGAALAGLAGVLLAPITG--VSPTMGLLLLLKAFAAVVL 220
LivH COG0559
Branched-chain amino acid ABC-type transport system, permease component [Amino acid transport ...
 50-261 5.07e-09

Branched-chain amino acid ABC-type transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440325 [Multi-domain]  Cd Length: 290  Bit Score: 56.22  E-value: 5.07e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091  50 ILAVGMTIV-IVSGGIDLSVGAVVAFSSVAGVMLMN-IGVNGWLSMLLMILFGATFGLISGV-----MIQYFNVQPFIAT 122
Cdd:COG0559    20 LIALGLTLIfGVMGVINFAHGEFVMLGAYVAYTLATlLGLPLWLALLLAVLVAALLGVLLERlvirpLRGAPPLALLLAT 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1817479091 123 LAMMFLARGLASIlsttpVVAADDSPILLLATDWKIIDGPKVNDFTITpGLLIAVLVVLGGMYFMHRTRMGRTVYAIGGN 202
Cdd:COG0559   100 IGLSLVLQGLVLL-----IFGADPRSFPALLSGSVELGGVSIPAYRLF-IIVVALVLLAALWLFLRRTRLGLAMRAVAQN 173

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1817479091 203 ESSAQLMGLPVSRTRIWIYVVSGALAGLAAIVYTAEVGGKAQnvTGIGWELDAIAAVVI 261
Cdd:COG0559   174 REAARLMGINVDRVIALTFALGAALAGLAGVLLAPIYSVSPT--MGFLLGLKAFAAVVL 230
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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