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Conserved domains on  [gi|1815786204|gb|QIE59217|]
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50S ribosomal protein L24 [Rasiella rasia]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RplX COG0198
Ribosomal protein L24 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L24 ...
 3-104 5.90e-52

Ribosomal protein L24 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L24 is part of the Pathway/BioSystem: Ribosome 50S subunit


:

Pssm-ID: 439968 [Multi-domain]  Cd Length: 104  Bit Score: 158.30  E-value: 5.90e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815786204   3 KLKIKSGDTVVVTAGDHKGSEGKVLRVDAEKNKAIVEGVNTVKKHEKPSAANPQGGITEKEAPIHVSNLSLVDPKSGDAT 82
Cdd:COG0198     2 KMKIKKGDTVIVIAGKDKGKRGKVLKVLPKKNRVIVEGVNIVKKHQKPNQQNPQGGIIEKEAPIHISNVMLVDPKTGKPT 81

                          90       100
                  ....*....|....*....|...
gi 1815786204  83 RVGYRM-EDGKKVRFAKKSNQVL 104
Cdd:COG0198    82 RVGFKVlEDGKKVRVCKKSGEVI 104
 
Name Accession Description Interval E-value
RplX COG0198
Ribosomal protein L24 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L24 ...
 3-104 5.90e-52

Ribosomal protein L24 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L24 is part of the Pathway/BioSystem: Ribosome 50S subunit


Pssm-ID: 439968 [Multi-domain]  Cd Length: 104  Bit Score: 158.30  E-value: 5.90e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815786204   3 KLKIKSGDTVVVTAGDHKGSEGKVLRVDAEKNKAIVEGVNTVKKHEKPSAANPQGGITEKEAPIHVSNLSLVDPKSGDAT 82
Cdd:COG0198     2 KMKIKKGDTVIVIAGKDKGKRGKVLKVLPKKNRVIVEGVNIVKKHQKPNQQNPQGGIIEKEAPIHISNVMLVDPKTGKPT 81

                          90       100
                  ....*....|....*....|...
gi 1815786204  83 RVGYRM-EDGKKVRFAKKSNQVL 104
Cdd:COG0198    82 RVGFKVlEDGKKVRVCKKSGEVI 104
rplX_bact TIGR01079
ribosomal protein L24, bacterial/organelle; This model recognizes bacterial and organellar ...
 4-104 6.60e-38

ribosomal protein L24, bacterial/organelle; This model recognizes bacterial and organellar forms of ribosomal protein L24. It excludes eukaryotic and archaeal forms, designated L26 in eukaryotes. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 273431 [Multi-domain]  Cd Length: 102  Bit Score: 122.76  E-value: 6.60e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815786204   4 LKIKSGDTVVVTAGDHKGSEGKVLRVDAEKNKAIVEGVNTVKKHEKPSAANPQGGITEKEAPIHVSNLSLVDPKSGDATR 83
Cdd:TIGR01079   1 MKIKKGDTVKVISGKDKGKRGKVLKVLPKKNKVIVEGVNMVKKHVKPVPANRQGGIIEKEAPIHISNVMLFDPKTGKATR 80

                          90       100
                  ....*....|....*....|..
gi 1815786204  84 VGYRM-EDGKKVRFAKKSNQVL 104
Cdd:TIGR01079  81 VGYRFeEDGKKVRVFKKNGEII 102
ribosomal_L24 pfam17136
Ribosomal proteins 50S L24/mitochondrial 39S L24; This is the family of bacterial 50S ...
 41-101 2.55e-28

Ribosomal proteins 50S L24/mitochondrial 39S L24; This is the family of bacterial 50S ribosomal subunit proteins L24. It also carries some mitochondrial 39S L24 proteins.


Pssm-ID: 465359  Cd Length: 60  Bit Score: 97.13  E-value: 2.55e-28
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1815786204  41 VNTVKKHEKPSAANPQGGITEKEAPIHVSNLSLVDPKSGDATRVGYRmEDGKKVRFAKKSN 101
Cdd:pfam17136   1 VNMVKKHVKPSQQNPQGGIIEKEAPIHVSNVMLVDPKCGKPTRVGFK-EDGKKVRVSKKTG 60
KOW_RPL26 cd06089
KOW motif of Ribosomal Protein L26; RPL26 and its bacterial paralogs RPL24 have a KOW motif at ...
 9-73 8.71e-27

KOW motif of Ribosomal Protein L26; RPL26 and its bacterial paralogs RPL24 have a KOW motif at their N terminal. KOW domain is known as an RNA-binding motif that is shared so far among some families of ribosomal proteins, the essential bacterial transcriptional elongation factor NusG, the eukaryotic chromatin elongation factor Spt5, the higher eukaryotic KIN17 proteins and Mtr4. RPL26 makes a very minor contributions to the biogenesis, structure, and function of 60s ribosomal subunits. However, RPL24 is essential to generate the first intermediate during 50s ribosomal subunits assembly. RPL26 have an extra-ribosomal function to enhances p53 translation after DNA damage.


Pssm-ID: 240513  Cd Length: 65  Bit Score: 93.35  E-value: 8.71e-27
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1815786204   9 GDTVVVTAGDHKGSEGKVLRVDAEKNKAIVEGVNTVKKHEKPSAANPQGGITEKEAPIHVSNLSL 73
Cdd:cd06089     1 GDEVQVIRGKDKGKQGKVLKVDRKKNRVIVEGVNVVKKHVKPSQENPQGGIIEVEAPIHISNVML 65
rplX PRK12281
50S ribosomal protein L24; Reviewed
 1-74 3.43e-24

50S ribosomal protein L24; Reviewed


Pssm-ID: 183399  Cd Length: 76  Bit Score: 87.40  E-value: 3.43e-24
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1815786204   1 MGKLKIKSGDTVVVTAGDHKGSEGKVLRVDAEKNKAIVEGVNTVKKHEKPSAANPQGGITEKEAPIHVSNLSLV 74
Cdd:PRK12281    2 KVKLKVKKGDMVKVIAGDDKGKTGKVLAVLPKKNRVIVEGVKIAKKAIKPSQKNPNGGFIEKEMPIHISNVKKV 75
KOW smart00739
KOW (Kyprides, Ouzounis, Woese) motif; Motif in ribosomal proteins, NusG, Spt5p, KIN17 and T54.
 5-30 1.31e-03

KOW (Kyprides, Ouzounis, Woese) motif; Motif in ribosomal proteins, NusG, Spt5p, KIN17 and T54.


Pssm-ID: 128978  Cd Length: 28  Bit Score: 33.46  E-value: 1.31e-03
                           10        20
                   ....*....|....*....|....*.
gi 1815786204    5 KIKSGDTVVVTAGDHKGSEGKVLRVD 30
Cdd:smart00739   1 KFEVGDTVRVIAGPFKGKVGKVLEVD 26
 
Name Accession Description Interval E-value
RplX COG0198
Ribosomal protein L24 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L24 ...
 3-104 5.90e-52

Ribosomal protein L24 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L24 is part of the Pathway/BioSystem: Ribosome 50S subunit


Pssm-ID: 439968 [Multi-domain]  Cd Length: 104  Bit Score: 158.30  E-value: 5.90e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815786204   3 KLKIKSGDTVVVTAGDHKGSEGKVLRVDAEKNKAIVEGVNTVKKHEKPSAANPQGGITEKEAPIHVSNLSLVDPKSGDAT 82
Cdd:COG0198     2 KMKIKKGDTVIVIAGKDKGKRGKVLKVLPKKNRVIVEGVNIVKKHQKPNQQNPQGGIIEKEAPIHISNVMLVDPKTGKPT 81

                          90       100
                  ....*....|....*....|...
gi 1815786204  83 RVGYRM-EDGKKVRFAKKSNQVL 104
Cdd:COG0198    82 RVGFKVlEDGKKVRVCKKSGEVI 104
rplX_bact TIGR01079
ribosomal protein L24, bacterial/organelle; This model recognizes bacterial and organellar ...
 4-104 6.60e-38

ribosomal protein L24, bacterial/organelle; This model recognizes bacterial and organellar forms of ribosomal protein L24. It excludes eukaryotic and archaeal forms, designated L26 in eukaryotes. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 273431 [Multi-domain]  Cd Length: 102  Bit Score: 122.76  E-value: 6.60e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815786204   4 LKIKSGDTVVVTAGDHKGSEGKVLRVDAEKNKAIVEGVNTVKKHEKPSAANPQGGITEKEAPIHVSNLSLVDPKSGDATR 83
Cdd:TIGR01079   1 MKIKKGDTVKVISGKDKGKRGKVLKVLPKKNKVIVEGVNMVKKHVKPVPANRQGGIIEKEAPIHISNVMLFDPKTGKATR 80

                          90       100
                  ....*....|....*....|..
gi 1815786204  84 VGYRM-EDGKKVRFAKKSNQVL 104
Cdd:TIGR01079  81 VGYRFeEDGKKVRVFKKNGEII 102
ribosomal_L24 pfam17136
Ribosomal proteins 50S L24/mitochondrial 39S L24; This is the family of bacterial 50S ...
 41-101 2.55e-28

Ribosomal proteins 50S L24/mitochondrial 39S L24; This is the family of bacterial 50S ribosomal subunit proteins L24. It also carries some mitochondrial 39S L24 proteins.


Pssm-ID: 465359  Cd Length: 60  Bit Score: 97.13  E-value: 2.55e-28
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1815786204  41 VNTVKKHEKPSAANPQGGITEKEAPIHVSNLSLVDPKSGDATRVGYRmEDGKKVRFAKKSN 101
Cdd:pfam17136   1 VNMVKKHVKPSQQNPQGGIIEKEAPIHVSNVMLVDPKCGKPTRVGFK-EDGKKVRVSKKTG 60
KOW_RPL26 cd06089
KOW motif of Ribosomal Protein L26; RPL26 and its bacterial paralogs RPL24 have a KOW motif at ...
 9-73 8.71e-27

KOW motif of Ribosomal Protein L26; RPL26 and its bacterial paralogs RPL24 have a KOW motif at their N terminal. KOW domain is known as an RNA-binding motif that is shared so far among some families of ribosomal proteins, the essential bacterial transcriptional elongation factor NusG, the eukaryotic chromatin elongation factor Spt5, the higher eukaryotic KIN17 proteins and Mtr4. RPL26 makes a very minor contributions to the biogenesis, structure, and function of 60s ribosomal subunits. However, RPL24 is essential to generate the first intermediate during 50s ribosomal subunits assembly. RPL26 have an extra-ribosomal function to enhances p53 translation after DNA damage.


Pssm-ID: 240513  Cd Length: 65  Bit Score: 93.35  E-value: 8.71e-27
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1815786204   9 GDTVVVTAGDHKGSEGKVLRVDAEKNKAIVEGVNTVKKHEKPSAANPQGGITEKEAPIHVSNLSL 73
Cdd:cd06089     1 GDEVQVIRGKDKGKQGKVLKVDRKKNRVIVEGVNVVKKHVKPSQENPQGGIIEVEAPIHISNVML 65
rplX PRK12281
50S ribosomal protein L24; Reviewed
 1-74 3.43e-24

50S ribosomal protein L24; Reviewed


Pssm-ID: 183399  Cd Length: 76  Bit Score: 87.40  E-value: 3.43e-24
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1815786204   1 MGKLKIKSGDTVVVTAGDHKGSEGKVLRVDAEKNKAIVEGVNTVKKHEKPSAANPQGGITEKEAPIHVSNLSLV 74
Cdd:PRK12281    2 KVKLKVKKGDMVKVIAGDDKGKTGKVLAVLPKKNRVIVEGVKIAKKAIKPSQKNPNGGFIEKEMPIHISNVKKV 75
rpl24 CHL00141
ribosomal protein L24; Validated
 3-78 7.66e-17

ribosomal protein L24; Validated


Pssm-ID: 214374  Cd Length: 83  Bit Score: 68.90  E-value: 7.66e-17
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1815786204   3 KLKIKSGDTVVVTAGDHKGSEGKVLRVDAEKNKAIVEGVNTVKKHEKPSAANPQGGITEKEAPIHVSNLSLVDPKS 78
Cdd:CHL00141    6 KMHVKIGDTVKIISGSDKGKIGEVLKIIKKSNKVIVKGINIKFKHIKPNKENEVGEIKQFEAPIHSSNVMLYNEES 81
Ribosomal_L26 pfam16906
Ribosomal proteins L26 eukaryotic, L24P archaeal; Ribosomal_L26 is a family of the 50S and the ...
 4-77 1.53e-07

Ribosomal proteins L26 eukaryotic, L24P archaeal; Ribosomal_L26 is a family of the 50S and the 60S ribosomal proteins from eukaryotes - L26 - and archaea - L25.


Pssm-ID: 465307 [Multi-domain]  Cd Length: 114  Bit Score: 45.58  E-value: 1.53e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1815786204   4 LKIKSGDTVVVTAGDHKGSEGKVLRVDAEKNKAIVEGVnTVKKhekpsaANPqggiTEKEAPIHVSNLSLVDPK 77
Cdd:pfam16906  40 LPIRKGDEVKVVRGDFKGREGKVVQVYRKKYRIHVEGV-TREK------ANG----TTVPVPIHPSKVVITKLK 102
KOW_NusG cd06091
NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; KOW_NusG motif ...
 3-39 7.81e-06

NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; KOW_NusG motif is one of the two domains of N-Utilization Substance G (NusG) a transcription elongation and Rho-termination factor in bacteria and archaea. KOW domain is known as an RNA-binding motif that is shared so far among some families of ribosomal proteins, the essential bacterial transcriptional elongation factor NusG, the eukaryotic chromatin elongation factor Spt5, the higher eukaryotic KIN17 proteins and Mtr4. The eukaryotic ortholog of NusG is Spt5 with multiple KOW motifs at its C-terminus.


Pssm-ID: 240515 [Multi-domain]  Cd Length: 56  Bit Score: 39.75  E-value: 7.81e-06
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 1815786204   3 KLKIKSGDTVVVTAGDHKGSEGKVLRVDAEKNKAIVE 39
Cdd:cd06091     1 EVDFEVGDTVRIISGPFAGFEGKVEEIDEEKGKVKVL 37
rplX_A_E TIGR01080
ribosomal protein uL24, archaeal/eukaryotic form; This model represents the archaeal and ...
 4-83 1.22e-05

ribosomal protein uL24, archaeal/eukaryotic form; This model represents the archaeal and eukaryotic branch of the ribosomal protein L24p/L26e family. Bacterial and organellar forms are represented by related model TIGR01079. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 273432  Cd Length: 114  Bit Score: 40.60  E-value: 1.22e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815786204   4 LKIKSGDTVVVTAGDHKGSEGKVLRVDAEKNKAIVEGVNTVKkhekpsaanpQGGiTEKEAPIHVSNLSLVDPKSGDATR 83
Cdd:TIGR01080  40 LPIRKGDEVRIVRGDFKGHEGKVSKVDRKRYRIYVEGVTKEK----------VDG-TEVPVPLHPSNVMITKLHLDDEKR 108
KOW cd00380
KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese); KOW domain is known ...
 9-50 3.02e-05

KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese); KOW domain is known as an RNA-binding motif that is shared so far among some families of ribosomal proteins, the essential bacterial transcriptional elongation factor NusG, the eukaryotic chromatin elongation factor Spt5, the higher eukaryotic KIN17 proteins and Mtr4. The KOW motif contains an invariants glycine residue and comprises alternating blocks of hydrophilic and hydrophobic residues.


Pssm-ID: 240504  Cd Length: 49  Bit Score: 38.35  E-value: 3.02e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1815786204   9 GDTVVVTAGDHKGSEGKVLRVDAEKNKAIVEGVNTVKKHEKP 50
Cdd:cd00380     1 GDVVRVLRGPYKGREGVVVDIDPRFGIVTVKGATGSKGAELK 42
KOW pfam00467
KOW motif; This family has been extended to coincide with ref. The KOW (Kyprides, Ouzounis, ...
 9-39 3.28e-05

KOW motif; This family has been extended to coincide with ref. The KOW (Kyprides, Ouzounis, Woese) motif is found in a variety of ribosomal proteins and NusG.


Pssm-ID: 425698 [Multi-domain]  Cd Length: 32  Bit Score: 37.75  E-value: 3.28e-05
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1815786204   9 GDTVVVTAGDHKGSEGKVLRVDAEKNKAIVE 39
Cdd:pfam00467   2 GDVVRVIAGPFKGKVGKVVEVDDKKNRVLVE 32
nusG PRK08559
transcription antitermination protein NusG; Validated
 6-39 1.09e-03

transcription antitermination protein NusG; Validated


Pssm-ID: 181467 [Multi-domain]  Cd Length: 153  Bit Score: 36.00  E-value: 1.09e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1815786204   6 IKSGDTVVVTAGDHKGSEGKVLRVDAEKNKAIVE 39
Cdd:PRK08559   95 IKEGDIVELIAGPFKGEKARVVRVDESKEEVTVE 128
KOW smart00739
KOW (Kyprides, Ouzounis, Woese) motif; Motif in ribosomal proteins, NusG, Spt5p, KIN17 and T54.
 5-30 1.31e-03

KOW (Kyprides, Ouzounis, Woese) motif; Motif in ribosomal proteins, NusG, Spt5p, KIN17 and T54.


Pssm-ID: 128978  Cd Length: 28  Bit Score: 33.46  E-value: 1.31e-03
                           10        20
                   ....*....|....*....|....*.
gi 1815786204    5 KIKSGDTVVVTAGDHKGSEGKVLRVD 30
Cdd:smart00739   1 KFEVGDTVRVIAGPFKGKVGKVLEVD 26
PTZ00194 PTZ00194
60S ribosomal protein L26; Provisional
 4-77 2.01e-03

60S ribosomal protein L26; Provisional


Pssm-ID: 185508  Cd Length: 143  Bit Score: 35.11  E-value: 2.01e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1815786204   4 LKIKSGDTVVVTAGDHKGSEGKVLRVDAEKNKAIVEGVNTVKKHEKPSAanpqggitekeAPIHVSNLSLVDPK 77
Cdd:PTZ00194   45 MPVRKDDEVMVVRGHHKGREGKVTAVYRKKWVIHIEKITREKANGEPVQ-----------IGIHPSNVIITKLK 107
KOW_GPKOW_B cd13153
KOW motif of the "G-patch domain and KOW motifs-containing protein" (GPKOW) repeat B; GPKOW ...
 9-39 9.53e-03

KOW motif of the "G-patch domain and KOW motifs-containing protein" (GPKOW) repeat B; GPKOW contains one G-patch domain and two KOW motifs. GPKOW is a nuclear protein that regulated by catalytic (C) subunit of Protein Kinase A (PKA) and bind RNA in vivo. PKA may be involved in regulating multiple steps in post-transcriptional processing of pre-mRNAs. KOW domain is known as an RNA-binding motif that is shared so far among some families of ribosomal proteins, the essential bacterial transcriptional elongation factor NusG, the eukaryotic chromatin elongation factor Spt5, the higher eukaryotic KIN17 proteins and Mtr4. GPKOW is also known as the T54 protein or MOS2 homolog.


Pssm-ID: 240517  Cd Length: 51  Bit Score: 31.75  E-value: 9.53e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1815786204   9 GDTVVVTAGDHKGSEGKVLRVDAEKNKAIVE 39
Cdd:cd13153     1 GAYVMVVRGKHRGQVGKLLERDKKKETAVVQ 31
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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