NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1802566705|gb|QHQ98225|]
View 

NADH dehydrogenase subunit 2 (mitochondrion) [Bos taurus]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475899)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-347 0e+00

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 504.77  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705   1 MNPIIFIIILLTIMLGTIIVMISSHWLLVWIGFEMNMLAIIPIMMKNHNPRATEASTKYFLTQSTASMLLMMAVIINLMF 80
Cdd:MTH00105    1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  81 SGQWTVMKLFNPMASMLMTMALAMKLGMAPFHFWVPEVTQGIPLSSGLILLTWQKLAPMSVLYQIFPSINLNLILTLSVL 160
Cdd:MTH00105   81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 161 SILIGGWGGLNQTQLRKIMAYSSIAHMGWMTAVLPYNPTMTLLNLIIYIIMTSTMFTMFMANSTTTTLSLSHTWNKTPIM 240
Cdd:MTH00105  161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 241 TVLILATLLSMGGLPPLSGFMPKWMIIQEMTKNNSIILPTFMAITALLNLYFYMRLTYSTTLTMFPSTNNMKMKWQFPLM 320
Cdd:MTH00105  241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                         330       340
                  ....*....|....*....|....*..
gi 1802566705 321 KKMTFLPTMVVLSTMMLPLTPMLSVLE 347
Cdd:MTH00105  321 KPMTLLPTLIILSTMLLPLTPMLSILE 347
 
Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-347 0e+00

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 504.77  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705   1 MNPIIFIIILLTIMLGTIIVMISSHWLLVWIGFEMNMLAIIPIMMKNHNPRATEASTKYFLTQSTASMLLMMAVIINLMF 80
Cdd:MTH00105    1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  81 SGQWTVMKLFNPMASMLMTMALAMKLGMAPFHFWVPEVTQGIPLSSGLILLTWQKLAPMSVLYQIFPSINLNLILTLSVL 160
Cdd:MTH00105   81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 161 SILIGGWGGLNQTQLRKIMAYSSIAHMGWMTAVLPYNPTMTLLNLIIYIIMTSTMFTMFMANSTTTTLSLSHTWNKTPIM 240
Cdd:MTH00105  161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 241 TVLILATLLSMGGLPPLSGFMPKWMIIQEMTKNNSIILPTFMAITALLNLYFYMRLTYSTTLTMFPSTNNMKMKWQFPLM 320
Cdd:MTH00105  241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                         330       340
                  ....*....|....*....|....*..
gi 1802566705 321 KKMTFLPTMVVLSTMMLPLTPMLSVLE 347
Cdd:MTH00105  321 KPMTLLPTLIILSTMLLPLTPMLSILE 347
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 19-296 2.20e-29

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 117.52  E-value: 2.20e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  19 IVMISS-HWLLVWIGFEMNMLAI-IPIMMKNHNPRATEASTKYFLTQSTAS--MLLMMAVI-----------INLMFSGQ 83
Cdd:COG1007   116 MLMASAnDLLTLFLGLELLSLSLyVLVAFRRDDRRSSEAALKYFLLGALSSgfLLYGISLLygatgslnlagIAAALAAG 195

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  84 WTVMKLFnPMASMLMTMALAMKLGMAPFHFWVPEVTQGIPLSSGLILLTWQKLAPMSVLYQI----FPSIN---LNLILT 156
Cdd:COG1007   196 GANSPLL-LLGLVLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLRLlveaFPGLAadwQLLLAV 274

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 157 LSVLSILIGGWGGLNQTQLRKIMAYSSIAHMGWM-TAVLPYNPTM---TLLNLIIYIIMTSTMFTMFMANSTTTTLSLSH 232
Cdd:COG1007   275 LAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLlLGLAAGTPLGvsaALFYLLAYLFMNLGAFAVILLLSRKGGEAEEI 354

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1802566705 233 -----TWNKTPIMTVLILATLLSMGGLPPLSGFMPKWMIIQEMTKNNSIILPTFMAITALLNLYFYMRL 296
Cdd:COG1007   355 edlagLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRV 423
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-286 9.37e-28

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 109.71  E-value: 9.37e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  23 SSHWLLVWIGFEMNMLAIIPIM-MKNHNPRATEASTKYFLTQSTASMLLMMAVIINLMFSGQWTVMKLFNP--------- 92
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKAltgglnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  93 --MASMLMTMALAMKLGMAPFHFWVPEVTQGIPLSSGLILL-TWQKLAP-----MSVLYQIFPSINLNLILTLSVLSILI 164
Cdd:pfam00361  81 llLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAaTLVKAGGyglirRSLLYLPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 165 GGWGGLNQTQLRKIMAYSSIAHMGWMTAVL----PYNPTMTLLNLIIYIIMTSTMFTMFMA-----NSTTTTLSLSHTWN 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLCAGSviyrrVHTRNIRDYGGLAK 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1802566705 236 KTPIMTVLILATLLSMGGLPPLSGFMPKWMIIQEMTKNNSIILPTFMAITA 286
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 18-296 4.27e-25

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 105.42  E-value: 4.27e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  18 IIVMISS-HWLLVWIGFEMNMLAI-IPIMMKNHNPRATEASTKYFLTQSTASMLLMMAVIINLMFSGQWTVMKLFNP--- 92
Cdd:TIGR01770 115 IFLLVSSnDLLSIYLGLELQSLCFyVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLLFlsn 194

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  93 ---------MASMLMTMALAMKLGMAPFHFWVPEVTQGIPLSSGLILLTWQKLAPMSVLYQIFPSI-------NLNLILT 156
Cdd:TIGR01770 195 gmlnislllLGIVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYIlfgfseaWQIFLAI 274

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 157 LSVLSILIGGWGGLNQTQLRKIMAYSSIAHMGWMTAVLPYNPTM----TLLNLIIYIIMTSTMFTMFMA------NSTTT 226
Cdd:TIGR01770 275 IAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEgikaVLFYIFIYALMSLGAFGVLSLlrsykdEWIEY 354

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 227 TLSLSHTWNKTPIMTVLILATLLSMGGLPPLSGFMPKWMIIQEMTKNNSIILPTFMAITALLNLYFYMRL 296
Cdd:TIGR01770 355 ISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRV 424
 
Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-347 0e+00

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 504.77  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705   1 MNPIIFIIILLTIMLGTIIVMISSHWLLVWIGFEMNMLAIIPIMMKNHNPRATEASTKYFLTQSTASMLLMMAVIINLMF 80
Cdd:MTH00105    1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  81 SGQWTVMKLFNPMASMLMTMALAMKLGMAPFHFWVPEVTQGIPLSSGLILLTWQKLAPMSVLYQIFPSINLNLILTLSVL 160
Cdd:MTH00105   81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 161 SILIGGWGGLNQTQLRKIMAYSSIAHMGWMTAVLPYNPTMTLLNLIIYIIMTSTMFTMFMANSTTTTLSLSHTWNKTPIM 240
Cdd:MTH00105  161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 241 TVLILATLLSMGGLPPLSGFMPKWMIIQEMTKNNSIILPTFMAITALLNLYFYMRLTYSTTLTMFPSTNNMKMKWQFPLM 320
Cdd:MTH00105  241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                         330       340
                  ....*....|....*....|....*..
gi 1802566705 321 KKMTFLPTMVVLSTMMLPLTPMLSVLE 347
Cdd:MTH00105  321 KPMTLLPTLIILSTMLLPLTPMLSILE 347
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-346 3.41e-137

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 393.40  E-value: 3.41e-137
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705   1 MNPIIFIIILLTIMLGTIIVMISSHWLLVWIGFEMNMLAIIPIMMKNHNPRATEASTKYFLTQSTASMLLMMAVIINLMF 80
Cdd:MTH00135    1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  81 SGQWTVMKLFNPMASMLMTMALAMKLGMAPFHFWVPEVTQGIPLSSGLILLTWQKLAPMSVLYQIFPSiNLNLILTLSVL 160
Cdd:MTH00135   81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPT-NPTLLITLGLT 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 161 SILIGGWGGLNQTQLRKIMAYSSIAHMGWMTAVLPYNPTMTLLNLIIYIIMTSTMFTMFMANSTTTTLSLSHTWNKTPIM 240
Cdd:MTH00135  160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPAL 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 241 TVLILATLLSMGGLPPLSGFMPKWMIIQEMTKNNSIILPTFMAITALLNLYFYMRLTYSTTLTMFPSTNNMKMKWQFPLM 320
Cdd:MTH00135  240 TALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPST 319

                         330       340
                  ....*....|....*....|....*.
gi 1802566705 321 KKMTFLPTMVVLSTMMLPLTPMLSVL 346
Cdd:MTH00135  320 QLTLPLAISTTATLMLLPLTPAILAL 345
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-343 1.52e-123

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 358.85  E-value: 1.52e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705   1 MNPIIFIIILLTIMLGTIIVMISSHWLLVWIGFEMNMLAIIPIMMKNHNPRATEASTKYFLTQSTASMLLMMAVIINLMF 80
Cdd:MTH00070    1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  81 SGQWTVMKLFNPMASMLMTMALAMKLGMAPFHFWVPEVTQGIPLSSGLILLTWQKLAPMSVLYQIFPSINLNLILTLSVL 160
Cdd:MTH00070   81 TGEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 161 SILIGGWGGLNQTQLRKIMAYSSIAHMGWMTAVLPYNPTMTLLNLIIYIIMTSTMFTMFMANSTTTTLSLSHTWNKTPIM 240
Cdd:MTH00070  161 STLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 241 TVLILATLLSMGGLPPLSGFMPKWMIIQEMTKNNSIILPTFMAITALLNLYFYMRLTYSTTLTMFPSTNNMKMKWQFPlM 320
Cdd:MTH00070  241 TSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRFK-N 319

                         330       340
                  ....*....|....*....|...
gi 1802566705 321 KKMTFLPTMVVLSTMMLPLTPML 343
Cdd:MTH00070  320 KTNNLLSLTIILSLMLLPITPTI 342
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-343 6.13e-121

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 352.20  E-value: 6.13e-121
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705   1 MNPIIFIIILLTIMLGTIIVMISSHWLLVWIGFEMNMLAIIPIMMKNHNPRATEASTKYFLTQSTASMLLMMAVIINLMF 80
Cdd:MTH00112    1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  81 SGQWTVMKLFNPMASMLMTMALAMKLGMAPFHFWVPEVTQGIPLSSGLILLTWQKLAPMSVLYQIFPSINLNLILTLSVL 160
Cdd:MTH00112   81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 161 SILIGGWGGLNQTQLRKIMAYSSIAHMGWMTAVLPYNPTMTLLNLIIYIIMTSTMFTMFMANSTTTTLSLSHTWNKTPIM 240
Cdd:MTH00112  161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 241 TVLILATLLSMGGLPPLSGFMPKWMIIQEMTKNNSIILPTFMAITALLNLYFYMRLTYSTTLTMFPSTNNMKMKWQFPlM 320
Cdd:MTH00112  241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTK-P 319

                         330       340
                  ....*....|....*....|...
gi 1802566705 321 KKMTFLPTMVVLSTMMLPLTPML 343
Cdd:MTH00112  320 KKNTLTATLTTLSTLLLPLSPMI 342
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 1-340 1.46e-95

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 287.60  E-value: 1.46e-95
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705   1 MNPIIFIIILLTIMLGTIIVMISSHWLLVWIGFEMNMLAIIPIMMKNHNPRATEASTKYFLTQSTASMLLMMAVIINLMF 80
Cdd:MTH00041    1 MNRNVLIFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  81 SGQWTVMKLFNPMASMLMTMALAMKLGMAPFHFWVPEVTQGIPLSSGLILLTWQKLAPMSVLYQIFPSINLNLILTLSVL 160
Cdd:MTH00041   81 SGSWSINGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 161 SILIGGWGGLNQTQLRKIMAYSSIAHMGWMTAVLPYNPTMTLLNLIIYIIMTSTMFTMFMANSTTTTLSLSHTWNKTPIM 240
Cdd:MTH00041  161 SVLVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPIS 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 241 TVLILATLLSMGGLPPLSGFMPKWMIIQEMTKNNSIILPTFMAITALLNLYFYMRLTYSTTLTMFPS-----TNNMKMKW 315
Cdd:MTH00041  241 AFLFILSILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQhsislFSWRNSGN 320

                         330       340
                  ....*....|....*....|....*
gi 1802566705 316 QFPLMKKMTFLPTMVVLSTMMLPLT 340
Cdd:MTH00041  321 ITVYGVILSILSSISILGLLLIPLF 345
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-346 1.95e-86

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 264.14  E-value: 1.95e-86
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705   1 MNPIIFIIILLTIMLGTIIVMISSHWLLVWIGFEMNMLAIIPIMMKNHNPRATEASTKYFLTQSTASMLLMMAVIINLMF 80
Cdd:MTH00200    1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  81 SGQWTVMKLFNPMASMLMTMALAMKLGMAPFHFWVPEVTQGIPLSSGLILLTWQKLAPMSVLYQIFPSINLNLILTLSVL 160
Cdd:MTH00200   81 SGQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 161 SILIGGWGGLNQTQLRKIMAYSSIAHMGWMTAVLPYNPTMTLLNLIIYIIMTSTMFTMFMANSTTTTLSLSHTWNKTPIM 240
Cdd:MTH00200  161 SVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPIL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 241 TVLILATLLSMGGLPPLSGFMPKWMIIQEMTKNNSIILPTFMAITALLNLYFYMRLTYSTTLTMFPSTNNMKMKWQFPLM 320
Cdd:MTH00200  241 SMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRTKSN 320

                         330       340
                  ....*....|....*....|....*.
gi 1802566705 321 KKMtFLPTMVVLSTMMLPLTPMLSVL 346
Cdd:MTH00200  321 SNL-LVGLLLLLSILGLPLTPQLLFL 345
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-343 1.41e-55

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 184.64  E-value: 1.41e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705   1 MNPIIFIIILLTIMLGTIIVMISSHWLLVWIGFEMNMLAIIPIMMKNHNPRATEASTKYFLTQSTASMLLMMAVIINLMF 80
Cdd:MTH00160    2 MMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNMLN 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  81 sgqwtvMKLFNPMASMLMTMALAMKLGMAPFHFWVPEVTQGIPLSSGLILLTWQKLAPMSVLYQIFpsiNLNLILTLSVL 160
Cdd:MTH00160   82 ------LMLFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLI---NNNFIIIIIIL 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 161 SILIGGWGGLNQTQLRKIMAYSSIAHMGWMTAVLPYNPTMTLLNLIIYIIMTSTMFTMFMANSTTTTLSLSHTWNKTPIM 240
Cdd:MTH00160  153 SAIIGAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKI 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 241 TVLILATLLSMGGLPPLSGFMPKWMIIQEMTKNNSIILPTFMAITALLNLYFYMRLTYSttlTMFPSTNNMKMKWQFPLM 320
Cdd:MTH00160  233 KFLLFLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYS---SLMLNYNKNKWNLKKKKN 309

                         330       340
                  ....*....|....*....|...
gi 1802566705 321 KKMTFLPTMVVLSTMMLPLTPML 343
Cdd:MTH00160  310 KFSLILNFLSFISLFGLILSSLL 332
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 16-320 4.91e-52

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 175.07  E-value: 4.91e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  16 GTIIVMISSHWLLVWIGFEMNMLAIIPIMMKNHNPRATEASTKYFLTQSTASMLLMMAVIINLMFSGQWTVMklfnpmas 95
Cdd:MTH00144   16 GTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSWFSM-------- 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  96 MLMTMALAMKLGMAPFHFWVPEVTQGIPLSSGLILLTWQKLAPMSVLYQIFPSINL-NLILTLSVLSILIGGWGGLNQTQ 174
Cdd:MTH00144   88 SLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLaYLLCVISVLSALVGSIGGLNQTQ 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 175 LRKIMAYSSIAHMGWMTAVLPYNPTMTLLNLIIYiIMTSTMFTMFMANSTTTTLSLSHTWNKTPIMTVLILATLLSMGGL 254
Cdd:MTH00144  168 VRALLAYSSISHTGWMLVAILHGSWLMWMYFLIY-IVSSGFLFFSLWSGDSGSMKDLGSLKPSYKTGLSIISLLLSLGGL 246

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1802566705 255 PPLSGFMPKWMIIQEMTKNNSIILPTFMAITALLNLYFYMRLTYSTTLTMFPSTNNMKMKWQFPLM 320
Cdd:MTH00144  247 PPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKVLNSSI 312
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 16-304 1.06e-46

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 161.10  E-value: 1.06e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  16 GTIIVMISSHWLLVWIGFEMNMLAIIPIMMKNHNPRATEASTKYFLTQSTASMLLMMAVIINLMFSGQwtvmkLFNPMAS 95
Cdd:MTH00011   18 GTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTMMWSFPSL-----LKNITAL 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  96 MLMtMALAMKLGMAPFHFWVPEVTQGIPLSSGLILLTWQKLAPMSVLYQIFPSINLNLILTLSVLSILIGGWGGLNQTQL 175
Cdd:MTH00011   93 MLL-VSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAMSALAGGLGGMNQTQL 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 176 RKIMAYSSIAHMGWMTAVLPYNPTMTLLNLIIYIIMTSTMFTMFMANSTTTTLSLSHTWNKTPIMTVLILATLLSMGGLP 255
Cdd:MTH00011  172 RPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLFIMLLSLGGLP 251

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 1802566705 256 PLSGFMPKWMIIQEMTKNNSIILPTFMAITALLNLYFYMRLTYSTTLTM 304
Cdd:MTH00011  252 PFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFNFMYLS 300
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 16-340 3.95e-38

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 138.65  E-value: 3.95e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  16 GTIIVMISSHWLLVWIGFEMNMLAIIPIMMKNHNPRATEASTKYFLTQSTASMLLMMAVIinLMFSGQWtvmklFNPMAS 95
Cdd:MTH00197   10 GVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGS--LSFSNLY-----LSLLSV 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  96 MLMTMALAMKLGMAPFHFWVPEVTQGIPLSSGLILLTWQKLAPMSVLyqIFPSINLNLILTLSVLSILIGGWGGLNQTQL 175
Cdd:MTH00197   83 VLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLIL--AFNSSSFMGLLICSVLSSLIGGIGGMNQSNI 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 176 RKIMAYSSIAHMGWMTAVLPYNPTMTLLNLIIYIIMTSTMFTMFMANSTTTTLSLSHTWNKTPIMTVLILATLLSMGGLP 255
Cdd:MTH00197  161 RQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFLSLGGLP 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 256 PLSGFMPKWMIIQEMTKNNSIILPTFMAITALLNLYFYMRLTYSTTLTMFPSTNNMKMKWQFPLMKkmtFLPTMVVLSTM 335
Cdd:MTH00197  241 PLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKSLILSNWMINFLMKINLLYSGL---FILLMMMLPLL 317


                  ....*
gi 1802566705 336 MLPLT 340
Cdd:MTH00197  318 MIFTM 322
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 16-296 3.63e-31

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 120.91  E-value: 3.63e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  16 GTIIVMISSHWLLVWIGFEMNMLAI-IPIMMKNHNPRATEASTKYFLTQSTASMLLMMAV-------------IINLMFS 81
Cdd:MTH00196    5 GILCLISSSNWLSVYLAIELQTLSLfILIAQNRGSGYSAEAGLKYFVLGALSSGLFLFGCallcgttgglhlsYINLVLN 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  82 GQWTVMKLFNPMASMLMTMALAMKLGMAPFHFWVPEVTQGIPLSSGLILLTWQKLAPMSVLYQIFPSINLNLILTLsvLS 161
Cdd:MTH00196   85 SGQSFSSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVNILLIGGL--FS 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 162 ILIGGWGGLNQTQLRKIMAYSSIAHMGWMTAVLPYNP----TMTLLNLIIYIIMTSTMFTMFMA--NSTTTTLSLSHTWN 235
Cdd:MTH00196  163 LFVGAIGALNQTKIKRLLAYSGIGHMGFVLWGIEIGSfesiQASLVYLFIYIIMSICVFSIILAlnVYKNLIIEFSGLSR 242

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1802566705 236 KTPIMTVLILATLLSMGGLPPLSGFMPKWMIIQEMTKNNSIILPTFMAITALLNLYFYMRL 296
Cdd:MTH00196  243 RLPILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRI 303
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 19-296 2.20e-29

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 117.52  E-value: 2.20e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  19 IVMISS-HWLLVWIGFEMNMLAI-IPIMMKNHNPRATEASTKYFLTQSTAS--MLLMMAVI-----------INLMFSGQ 83
Cdd:COG1007   116 MLMASAnDLLTLFLGLELLSLSLyVLVAFRRDDRRSSEAALKYFLLGALSSgfLLYGISLLygatgslnlagIAAALAAG 195

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  84 WTVMKLFnPMASMLMTMALAMKLGMAPFHFWVPEVTQGIPLSSGLILLTWQKLAPMSVLYQI----FPSIN---LNLILT 156
Cdd:COG1007   196 GANSPLL-LLGLVLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLRLlveaFPGLAadwQLLLAV 274

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 157 LSVLSILIGGWGGLNQTQLRKIMAYSSIAHMGWM-TAVLPYNPTM---TLLNLIIYIIMTSTMFTMFMANSTTTTLSLSH 232
Cdd:COG1007   275 LAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLlLGLAAGTPLGvsaALFYLLAYLFMNLGAFAVILLLSRKGGEAEEI 354

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1802566705 233 -----TWNKTPIMTVLILATLLSMGGLPPLSGFMPKWMIIQEMTKNNSIILPTFMAITALLNLYFYMRL 296
Cdd:COG1007   355 edlagLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRV 423
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 16-267 3.24e-29

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 117.04  E-value: 3.24e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  16 GTIIVMISSHWLLVWIGFEMNMLAI-IPIMMKNHNPRATEASTKYFLTQSTASMLLMMAVIINLMFSGQWTVMK----LF 90
Cdd:MTH00199  109 GSLLLVSSINWLSIYLAIELQTLTLfILVALKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGETSIQGinsiLT 188

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  91 NPMASMLMTMALAMKLGMAPFHFWVPEVTQGIPLSSGLILLTWQKLAPMSVLYQIFPSInlNLILTLSVLSILIGGWGGL 170
Cdd:MTH00199  189 GDVGKILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVT--NVVLICAVLSIIYGAIGAL 266

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 171 NQTQLRKIMAYSSIAHMGWMTAVLPYNP----TMTLLNLIIYIIMTSTMFTMFMANSTTTTLS--LSHTWNKTPIMTVLI 244
Cdd:MTH00199  267 NQTKIKRLLAYSGIGHMGFILFGVAIGSfesiQASLIYMIIYVIMSICSFSIILSLKLTKGLIveVSGLSRKNPVIALTL 346

                         250       260
                  ....*....|....*....|...
gi 1802566705 245 LATLLSMGGLPPLSGFMPKWMII 267
Cdd:MTH00199  347 ALTFLSIAGIPPLAGFLSKWLIL 369
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-286 9.37e-28

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 109.71  E-value: 9.37e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  23 SSHWLLVWIGFEMNMLAIIPIM-MKNHNPRATEASTKYFLTQSTASMLLMMAVIINLMFSGQWTVMKLFNP--------- 92
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKAltgglnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  93 --MASMLMTMALAMKLGMAPFHFWVPEVTQGIPLSSGLILL-TWQKLAP-----MSVLYQIFPSINLNLILTLSVLSILI 164
Cdd:pfam00361  81 llLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAaTLVKAGGyglirRSLLYLPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 165 GGWGGLNQTQLRKIMAYSSIAHMGWMTAVL----PYNPTMTLLNLIIYIIMTSTMFTMFMA-----NSTTTTLSLSHTWN 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLCAGSviyrrVHTRNIRDYGGLAK 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1802566705 236 KTPIMTVLILATLLSMGGLPPLSGFMPKWMIIQEMTKNNSIILPTFMAITA 286
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 18-296 4.27e-25

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 105.42  E-value: 4.27e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  18 IIVMISS-HWLLVWIGFEMNMLAI-IPIMMKNHNPRATEASTKYFLTQSTASMLLMMAVIINLMFSGQWTVMKLFNP--- 92
Cdd:TIGR01770 115 IFLLVSSnDLLSIYLGLELQSLCFyVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLLFlsn 194

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  93 ---------MASMLMTMALAMKLGMAPFHFWVPEVTQGIPLSSGLILLTWQKLAPMSVLYQIFPSI-------NLNLILT 156
Cdd:TIGR01770 195 gmlnislllLGIVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYIlfgfseaWQIFLAI 274

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 157 LSVLSILIGGWGGLNQTQLRKIMAYSSIAHMGWMTAVLPYNPTM----TLLNLIIYIIMTSTMFTMFMA------NSTTT 226
Cdd:TIGR01770 275 IAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEgikaVLFYIFIYALMSLGAFGVLSLlrsykdEWIEY 354

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 227 TLSLSHTWNKTPIMTVLILATLLSMGGLPPLSGFMPKWMIIQEMTKNNSIILPTFMAITALLNLYFYMRL 296
Cdd:TIGR01770 355 ISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRV 424
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
18-296 1.04e-24

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 104.13  E-value: 1.04e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  18 IIVMISS-HWLLVWIGFEMNMLAI-IPIMMKNHNPRATEASTKYFLTQSTASMLLMMAVIINLMFSGQWTVMKLFNPMAS 95
Cdd:PRK05777  116 MMVMVSAnDLLTLFLGLELLSLPLyALAALRRDRRRSLEAAIKYFVLGALASGFLLYGMSLLYGATGSLSFAGIAKALAD 195

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  96 ------------MLMTMALAMKLGMAPFHFWVPEVTQGIPLSSGLILLTWQKLAPMS----VLYQIFPSINL---NLILT 156
Cdd:PRK05777  196 gsgnsllllfglVFLLVGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAvllrLLVVAFGGLSEdwqQVLAI 275

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 157 LSVLSILIGGWGGLNQTQLRKIMAYSSIAHMGWM-TAVLPYNPTM---TLLNLIIYIIMTSTMFTMFM----ANSTTTTL 228
Cdd:PRK05777  276 IAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLlVGLAAGTAEGysaVLFYLLAYLFMTLGAFGVISllrrKGGEAESI 355

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1802566705 229 SLSHTWNKT-PIMTVLILATLLSMGGLPPLSGFMPKWMIIQEMTKNNSIILPTFMAITALLNLYFYMRL 296
Cdd:PRK05777  356 SDFAGLSKRsPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYYLRV 424
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 16-296 2.39e-21

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 94.06  E-value: 2.39e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  16 GTIIVMISSHWLLVWIGFEMNMLAIIPIMMKNHNPRATEASTKYFLTQSTASMLLMMAVIINLMFSGQWT------VMKL 89
Cdd:COG0651   119 GMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNmadlaaRLAE 198

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  90 FNPM----ASMLMTMALAMKLGMAPFHFWVPE-----------VTQGIPLSSGLILLtwqklapMSVLYQIFPSINLN-- 152
Cdd:COG0651   199 LDPGlllaAFALLLVGFGIKAALFPLHFWLPDaypaapspvsaLLSGLLTKVGVYAI-------LRVLTLLFGADPALfl 271

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 153 --LILTLSVLSILIGGWGGLNQTQLRKIMAYSSIAHMGWMTAVLPYNPTMTLLNLIIYII----MTSTMF----TMFMAN 222
Cdd:COG0651   272 gtLLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHLLnhalAKALLFlaagAIERAT 351

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1802566705 223 STTTTLSLSHTWNKTPIMTVLILATLLSMGGLPPLSGFMPKWMIIQEMTKNNSIILPTFMAITALLNLYFYMRL 296
Cdd:COG0651   352 GTRDLDKLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAYFVRI 425
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 16-267 3.23e-13

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 70.66  E-value: 3.23e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  16 GTIIVMISSHWLLVWIGFEMNMLAIIPIMMKNHNPRAT---------EASTKYFLTQSTASMLLMMAVIINLMFSG---- 82
Cdd:MTH00198  200 GGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGCALYFGFTGnegm 279

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  83 ---------QWTVMKLFN-PMASMLMTMALAMKLGMAPFHFWVPEVTQGIPLSSGLILLTWQKLAPMSVLYQIFpsINLN 152
Cdd:MTH00198  280 lgtilsatlETTNIELRQgSLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILLTSLV--ITSK 357

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 153 LILTLSVLSILIGGWGGLNQTQLRKIMAYSSIAHMGWMTAVLPYNPTMTLLN----LIIYIIMTSTMFTMFMA------- 221
Cdd:MTH00198  358 LLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFILIGVSAGTYESLQAswtyAVTYLVSALASFTVICTleefgtr 437

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 222 --------------NSTTTTLSLSHTWNKTPIMTVLILATLLSMGGLPPLSGFMPKWMII 267
Cdd:MTH00198  438 tptsrqrdgsfgnyNLVRRLVDLTILSRGQPYIAFSLAIVFLSLAGIPPLLGFLGKWFIL 497
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 46-299 1.20e-11

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 65.50  E-value: 1.20e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  46 KNHNPRATEASTKYFLTQSTASMLLMMAVII-----NLMFSGQWTVMKLFNP-----MASMLMTMALAMKLGMAPFHFWV 115
Cdd:PRK08376  164 RNDTWEAIEAGIKYMFVGSLASSMVLLGIALlygqyGTLNMAYLAVKMSENPtvvakIALALFIAGLAMKSGAVPVHMWL 243

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 116 PEVTQGIPLSSGLILLTWQK---LAPMSVLYQIF-PSINLN----LILTLSVLSILIGGWGGLNQTQLRKIMAYSSIAHM 187
Cdd:PRK08376  244 PDAYPAAPSSISAMLLVIKQaglYALARVLFSIYgPAINLAtvgwVIIILGCLTMFVGVAMAVVQKDVKRLLAYHSVSQI 323

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 188 GWM-----TAVLPYNPT------MTLLNLIIYIIMTSTMFTMFMANSTTTTLSLSHTWN---------KTPIMTVLILAT 247
Cdd:PRK08376  324 GYMllglgVGLAALGDPamasygEIALAGGIYHIVNHALYKALLFLTAGAVIYETGTRNlnelgglarTMPKTTIAFLIG 403

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1802566705 248 LLSMGGLPPLSGFMPKWMIIQEMTKNNSiILPTFMAITALLNLYFYMRLTYS 299
Cdd:PRK08376  404 AAAIVGLPPFNGFASKWLIYESSALFNP-ILGVIAMIGSVLTLASFVKVFHT 454
NADH_dehy_S2_C pfam06444
NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region ...
 291-341 2.10e-11

NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region specific to the eukaryotic NADH dehydrogenase subunit 2 protein and is found in conjunction with pfam00361.


Pssm-ID: 461914 [Multi-domain]  Cd Length: 51  Bit Score: 58.42  E-value: 2.10e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1802566705 291 YFYMRLTYSTTLTMFPSTNNMKMKWQFPLMKKMTFLPTMVVLSTMMLPLTP 341
Cdd:pfam06444   1 FFYLRLSYSTTLTLFPNTNNSKMKWRFNSTKNTLLLPTLTTLSILLLPLTP 51
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
28-295 7.48e-11

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 63.15  E-value: 7.48e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  28 LVWIGFEMNMLAIIPIMMKNH---NPRATEASTKYFLTQSTASMLLMMAVIINLMFSGQWTVMKLFNPM----ASMLMTM 100
Cdd:PRK02504  132 LVMIFISLETLSIASYLLTGYmkrDPRSNEAALKYLLIGAASSAIFLYGSSLLYGLSGGSTQLSAIALAlitsPSLGLAL 211

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 101 AL-------AMKLGMAPFHFWVPEVTQGIPLSSGLILLTWQKLA----PMSVLYQIFPSIN--LNLILT-LSVLSILIGG 166
Cdd:PRK02504  212 ALvfviagiAFKISAVPFHQWTPDVYEGSPTPVVAFLSVGSKAAgfalAIRLLVTAFPSFDeqWKLLFTaLAILSMVLGN 291

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 167 WGGLNQTQLRKIMAYSSIAHMGW----MTAVLPYNPTMTLLNLIIYIIMTSTMFT---MF-MANSTTTTLSLSHTWNKTP 238
Cdd:PRK02504  292 VVALAQTSMKRMLAYSSIGQAGFvmigLVAGTEAGYASMVFYLLAYLFMNLGAFAcviLFsLRTGTDQISDYAGLYQKDP 371

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1802566705 239 IMTVLILATLLSMGGLPPLSGFMPKWMIIQEMTKNNSIILPTFMAITALLNLYFYMR 295
Cdd:PRK02504  372 LLTLGLSLCLLSLGGIPPLAGFFGKIYLFWAGWQAGLYLLVLVGLVTSVISIYYYIR 428
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 49-298 2.46e-10

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 61.43  E-value: 2.46e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  49 NPRATEASTKYFLTQSTASMLLMMAVIINLMFSGQWTVMKL---FNPMASMLMTM-----ALAMKLGMAPFHFWVPEV-T 119
Cdd:PRK08375  151 DRRALAAARKYLIVGLIGSTFLLIGVGLLYGVTGTLNMADLagaLAENPTVVTAFgfvllALALKAAVFPLHTWLPRAyP 230

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 120 QGIPLSSGLILLTWQKLAP---MSVLYQIFP------SINLNLILTLSVLSILIGGWGGLNQTQLRKIMAYSSIAHMGWM 190
Cdd:PRK08375  231 AAPPVVTALLSGLVTKVAVyalIRIYFTVFGgdfrfaLGLGWLLAVLALLSMLVGSLAALGQDDVKRVLAYSTVSQMGYI 310

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 191 TAVL----PYNPTMTLLNLIIYIIMTSTMF----TMFMANSTTTTLSLSHTWNKTPIMTVLILATLLSMGGLPPLSGFMP 262
Cdd:PRK08375  311 LLGLalltPLALAAGLLHLLHHALMKGALFlaagAIEVTYGTRRLSELSGLGRRMPLTAAAFAVASLSLIGVPPTSGFVS 390

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 1802566705 263 KWMIIQEMTKNNSIILPTFMAITALLNLYFYMRLTY 298
Cdd:PRK08375  391 KWYLVVGAVEAGQWLVLAVLLASSLLALLYFLRIWY 426
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 43-299 5.36e-10

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 60.37  E-value: 5.36e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  43 IMMKNHNPRATEASTKYFLTQSTASMLLMMAVII-------------NLMFSGQW---TVMKLFNPMASMLMTMALAM-- 104
Cdd:PRK12667  153 VAYYRDRGDAVEAAIKYALIGAVGTTLYFLALAFlyatfgtlnmadlSAKIRGLSfplTGGLAGNPPLALGVALALALwa 232

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 105 ---KLGMAPFHFWVPEVTQGIP-----LSSGLILLTwQKLAPMSVLYQIFP---------SINLNLILTLSVLSILIGGW 167
Cdd:PRK12667  233 ftiKAAIFPNHFWLPDAHPAAPspvsaMLSGLVVNV-GAYAIIRFLYTIFGispslidfrAALSPILIILGAVSAIIGAL 311

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 168 GGLNQTQLRKIMAYSSIAHMGWMTAVLPYNPTMTLLNLIIYIIMTSTMFTM-FMANSTTTTLS-------LSHTWNKTPI 239
Cdd:PRK12667  312 MMVVQKDVKRLLAYSTISHMGYIFMGIGIGTQLGLAAALFHIINHAIAKSLlFLASGVFIHAAgtrdideLAGLGRKMPI 391

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 240 MTVLILATLLSMGGLPPLSGFMPKWMIIQEMTKNNSIILPTFMAITALLNLYFYMRLTYS 299
Cdd:PRK12667  392 ASFAFLIGALSLVGIPPLNGFFSKLLLFNALLESGFYLPALVLLIASAISLVGYFRAWYS 451
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 16-288 1.74e-09

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 58.80  E-value: 1.74e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  16 GTIIVMISSHWLLVWIGFEMN---MLAIIPIMMKNHNPRAteaSTKYFLTQSTASmLLMMAVIINLMFSGQWT---VMKL 89
Cdd:TIGR01972 118 GVIGVFLALDLFLFYVFWEAMlipMYLLIGVWGGPNRIYA---AMKFFLYTLAGS-LLMLLAILGLYFLGGGTfdlLELL 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  90 FNPMASMLMT-------MALAMKLGMAPFHFWVPEV-----TQGIPLSSGLILltwqKLAP---MSVLYQIFPS---INL 151
Cdd:TIGR01972 194 NLPLPFGVQTwlflaffIAFAVKVPLFPLHTWLPDAhveapTAGSVILAGVLL----KMGTygfLRFNLPLFPDaslYFA 269

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 152 NLILTLSVLSILIGGWGGLNQTQLRKIMAYSSIAHMGWMT-AVLPYNPTMT---LLNLIIYIIMTSTMFtmFMANST--- 224
Cdd:TIGR01972 270 PVLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVLlGIFSFNELGIsgaVFQMISHGLITAALF--LLVGVLyer 347

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1802566705 225 ---TTTLSLSHTWNKTPIMTVLILATLLSMGGLPPLSGFMPKWMIIQEMTKNNsiILPTFMAITALL 288
Cdd:TIGR01972 348 ahtRDIAKYGGLANKMPVLAAFFMLFAMASLGLPGTSGFVGEFLILLGSFKVN--PVVAFLAALGIV 412
ndhB CHL00049
NADH dehydrogenase subunit 2
 51-296 3.98e-09

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 57.71  E-value: 3.98e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  51 RATEASTKYFLTQSTASMLLMM-----------AVIINLMFSGqWTVMKLFNPMAS----MLMTMALAMKLGMAPFHFWV 115
Cdd:CHL00049  159 RSNEATMKYLLMGGASSSILVYgfswlyglsggEIELQEIVNG-LINTQMYNSPGIsialIFITVGIGFKLSLAPFHQWT 237

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 116 PEVTQGIPLSSGLILLTWQKLAPMSVLYQI----FPSIN--LNLILT-LSVLSILIGGWGGLNQTQLRKIMAYSSIAHMG 188
Cdd:CHL00049  238 PDVYEGSPTPVVAFLSVTSKVAASALATRIfdipFYFSSneWHLLLEiLAILSMILGNLIAITQTSMKRMLAYSSIGQIG 317

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 189 W-MTAVLPYNP----TMTLLNLIIYIIMTSTMF---TMF-MANSTTTTLSLSHTWNKTPIMTVLILATLLSMGGLPPLSG 259
Cdd:CHL00049  318 YvIIGIIVGDSndgyASMITYMLFYIFMNLGTFaciVLFgLRTGTDNIRDYAGLYTKDPFLALSLALCLLSLGGIPPLAG 397

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 1802566705 260 FMPKWMIIQEMTKNNSIILPTFMAITALLNLYFYMRL 296
Cdd:CHL00049  398 FFGKLYLFWCGWQAGLYFLVSIGLLTSVISIYYYLKI 434
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 55-288 8.28e-09

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 56.63  E-value: 8.28e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  55 ASTKYFLTQSTASMLLMMAVIINLMFSGQWT------VMKLFNPMASML----MTMALAMKLGMAPFHFWVPEV-----T 119
Cdd:COG1008   162 AAIKFFLYTLAGSLLMLVAILALYFLAGALTfdiaelAAAPLPLTAQLLlflaFFIAFAVKVPMFPFHTWLPDAhveapT 241

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 120 QGIPLSSGLILltwqKLAPMSVL---YQIFP---SINLNLILTLSVLSILIGGWGGLNQTQLRKIMAYSSIAHMGWMT-A 192
Cdd:COG1008   242 AGSVLLAGVLL----KMGGYGLLrfaLPLFPeasAYFAPLLAALGVIGIIYGALVALAQTDLKRLIAYSSVSHMGFVLlG 317

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 193 VLPYNPTM---TLLNLIIYIIMTSTMF-----------TMFMANsttttlsLSHTWNKTPIMTVLILATLLSMGGLPPLS 258
Cdd:COG1008   318 IFALNPLGlqgAVLQMVSHGLITAALFllvgvlydrthTRDIAD-------LGGLAKRMPVLAALFLLAALASLGLPGTS 390

                         250       260       270
                  ....*....|....*....|....*....|
gi 1802566705 259 GFMPKWMIIQEMTKNNSIIlpTFMAITALL 288
Cdd:COG1008   391 GFVGEFLVLLGAFQVNPWL--AILAALGLI 418
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 47-300 2.04e-08

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 55.54  E-value: 2.04e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  47 NHNPRATEASTKYFLTQSTASMLLMMAVIINLMFSGQWTVMKLFN----PMASMLMTMALAM-------KLGMAPFHFWV 115
Cdd:COG1009   155 YEKPSARRAARKAFLVTRVGDLGLLLGILLLGAIAGTLNFSELLAaaptILSSPLLTLILLLlllgafgKSAQFPLHFWL 234

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 116 PE-----------------VTQGIPLssglilltwqkLAPMSVLYQIFPSInLNLILTLSVLSILIGGWGGLNQTQLRKI 178
Cdd:COG1009   235 PDamegptpvsallhaatmVKAGVYL-----------LARLSPLFALSPVW-LTVVAIIGAITALFAALIALAQTDIKRV 302

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 179 MAYSSIAHMGWMTAVLPYNPT-------MT------LLNLIIYIIMTST----MFTMfmansttttlslSHTWNKTPIMT 241
Cdd:COG1009   303 LAYSTVSQLGYMFLALGVGAYvaalfhlLThaffkaLLFLGAGSVIHATgtrdIRKM------------GGLRKKMPITA 370

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1802566705 242 VLILATLLSMGGLPPLSGFMPKWMIIQEM--TKNNSIILPTFMAITALLNLYFYMRLTYST 300
Cdd:COG1009   371 ITFLIGALSLAGIPPFAGFFSKEAILEAAleAGGLGPLLLAVALLGAFLTAFYSFRLFFLV 431
PRK12663 PRK12663
Na+/H+ antiporter subunit D;
92-296 7.67e-08

Na+/H+ antiporter subunit D;


Pssm-ID: 237163 [Multi-domain]  Cd Length: 497  Bit Score: 53.80  E-value: 7.67e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  92 PMASMLMTMALAMKLGMAPFhFWVPEVTQGIPLSSGLI---LLT----WQKLAPMSVLYQIFPSINLNLILTLSVLSILI 164
Cdd:PRK12663  207 TTIALLFLLAFGMKAALFPF-MWLPAAYHTPNTEVAALfaaLLTkvgiYALIRVFTLLFPQERELLHPLLATMAAITMVI 285

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 165 GGWGGLNQTQLRKIMAYSSIAHMGWMTAVLPYNPTMTLLNLIIY-----IIMTSTMFTMFMANSTTTTLSLSHT---WNK 236
Cdd:PRK12663  286 GALGALAYKDIRRIAGYQVISSIGFILLGLALGTPAGINGAIFYlvhdmVVKTALFLIAGSLVRLTGYRSLQYLgglYRK 365

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 237 TPIMTVLILATLLSMGGLPPLSGFMPKWMIIQEMTKNNSIILPTFMAITALLNLYFYMRL 296
Cdd:PRK12663  366 EPLFGALFLILIFAIGGLPPFSGFWGKVLLVQGALDNGAYILLALMLITSLITMYSLFRI 425
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 16-332 3.43e-07

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 51.92  E-value: 3.43e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  16 GTIIVMISSHWLLVWIGFEMNMLAIIpIMMKNHNPRATEASTKYFLTQSTASMLLMMAV--------------IINLMFS 81
Cdd:PRK08668  110 GVLGVFLANDLLTLYIFWEIMTFSSF-MMVPMGKKESRKASLKYFVLSAIGAYAMLYAIfliyaktgtfdfadISQGLIN 188

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  82 GQWTVMKLfnpMASMLMTMALAMKLGMAPFHFWVPEVTQGIP------LSSGL-------ILLTWQKLAPMSVLYQIFPS 148
Cdd:PRK08668  189 DTSTGFAL---IVFLFLLAFGVAKAGIFPLHVWAPDAYSEAPqsfsavLSGQLsklgaygFLLVLYVLPGTKLFSEFGTY 265

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 149 INLNL----ILTLSVLSILIGGWGGLNQTQLRKIMAYSSIAHMGWMTAVL----PYNPTMTLLNLIIYIIMTSTMFTMFM 220
Cdd:PRK08668  266 RGVPLfnyiLAWLGNISIIVGTLMAILQEDIKKLIAYSSVANGGYILVGLglgtSLGFAGGLFHVFNHALFKGLFFLIFA 345

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 221 ANSTTTTLSLSHTWN----KTPIMTVLILATLLSMGGLPPLSGFMPKWMIIQEMTKNNSIILPTFMAITALLNLYFYMRL 296
Cdd:PRK08668  346 AVIYRTGTTKISEMGglieKMPFTFAMYLVAIISLAGIPPMSGFASKWLIFEALISKGMPITAFMAFFGSIGSFLYVFRP 425

                         330       340       350
                  ....*....|....*....|....*....|....*.
gi 1802566705 297 TYSTTLTMFPSTNNMKMKWQFPLMKKMTFLPTMVVL 332
Cdd:PRK08668  426 LAGVFLGQLPSDHKDVKEAPLPMLIPMAILVLLNVV 461
PRK12650 PRK12650
DUF4040 family protein;
81-263 1.66e-06

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 50.04  E-value: 1.66e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  81 SGQWTVMKLFNPMASMLMTMALAMKLGMAPFHFWVPEVTQGI-PLSSGLILLTWQK-----LAPMSVLYQIFPSINLNLI 154
Cdd:PRK12650  197 SDVWAEKPGLTTVVAVLIAVAAFTKSAQFPFHFWLPEAMAAItPVSAFLHAAAVVKagiylLLRFSPVFHDVAVWNWLLI 276

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 155 lTLSVLSILIGGWGGLNQTQLRKIMAYSSIAHMGWMTAVL----PYNPTMTLLNLIIYIIMTSTMFtMFMA-----NSTT 225
Cdd:PRK12650  277 -IVGMITALMGAVFAVQKTDLKKLTAYSTVSQLGWIVATIgvgtPFALTAAVVHTLAHALFKSSLF-MLIGvvdhqAGTR 354

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1802566705 226 TTLSLSHTWNKTPIMTVLILATLLSMGGLPPLSGFMPK 263
Cdd:PRK12650  355 DIRRLGSLWRRMPFTFVSVTIAALSMAAVPPLFGFVSK 392
ND4 MTH00226
NADH dehydrogenase subunit 4; Provisional
 100-326 2.79e-06

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214466 [Multi-domain]  Cd Length: 505  Bit Score: 48.76  E-value: 2.79e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 100 MALAMKLGMAPFHFWVPEVTQGIPLSSGL----ILLTWQKLAPMSVLYQIFPSINLNL---ILTLSVLSILIGGWGGLNQ 172
Cdd:MTH00226  238 LAMAVKIPIFPFHIWLPKAHVEAPVAGSVllagILLKLGGYGLVRLSWPILPLGAQNLapaVIAMGIVGIVYGSFATCRQ 317

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 173 TQLRKIMAYSSIAHMGWMTAVLPYNPTMTLLNLIIYI----IMTSTMFTMFMANSTTTTLSLSHTWN----KTPIMTVLI 244
Cdd:MTH00226  318 IDVKRLVAYSSVAHMGLVSITLVTHDIIGLTGSIFIMlahgIVSSLLFILVTILYDRHHTRLIKYYRglsiTMPIWGTIM 397

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 245 LATLLSMGGLPPLSGFMPKWMIIQEMTKNNSII---LPTFMAITALLNLYFYMRLTYSTTLTMFPSTNNMKMKwQFPLMK 321
Cdd:MTH00226  398 IVTSLANVAVPPSGNFIGEYLSILSSFNWNPIIgvfVCSGVILSAVYSFYFANRVTFGAPGNLITFARDVNRR-EFYITA 476


                  ....*
gi 1802566705 322 KMTFL 326
Cdd:MTH00226  477 SMVFF 481
ND4 MTH00204
NADH dehydrogenase subunit 4; Provisional
 100-191 5.71e-06

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 164750 [Multi-domain]  Cd Length: 485  Bit Score: 47.75  E-value: 5.71e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 100 MALAMKLGMAPFHFWVPEVTQGIPLSSGLILL-TWQKLAPMSVL---YQIFPSINL---NLILTLSVLSILIGGWGGLNQ 172
Cdd:MTH00204  217 LSLAVKIPQIPFHIWLPQAHVEAPVAGSVILAgILLKLGGYGFLrfsWPLFPAASEyfaPLIVMLSVIAVIYGSLTTCRQ 296

                          90
                  ....*....|....*....
gi 1802566705 173 TQLRKIMAYSSIAHMGWMT 191
Cdd:MTH00204  297 VDFKRLIAYSSVAHMGLVP 315
PRK06277 PRK06277
energy conserving hydrogenase EhbF;
33-302 1.09e-05

energy conserving hydrogenase EhbF;


Pssm-ID: 235767 [Multi-domain]  Cd Length: 478  Bit Score: 46.95  E-value: 1.09e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  33 FEMNMLAIIPIMMKNHNPRATEASTKYFLTQSTASMLLMMAVIINLMFSGQWT----VMKLFNPMASMLMTMALAMKL-- 106
Cdd:PRK06277  129 FEIAAIVQVGLVIASGTEEAYKAALKYMILGNVAGSILLLGIGFLLASTGTLNitdiHNALLVNPTSPVIYGGLLLLIfg 208

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 107 -----GMAPFHFWVPEVTQGIPLSSGLILLTWQKL---APMSVLYQIF------PSINLnLILTLSVLSILIGGWGGLNQ 172
Cdd:PRK06277  209 llygsGLPPFHTIKSDIYAKAKPFGSALLQTFSKFvlvALMLVIFKLFgglsyfPSAQG-VLIALSVLAMVFGVVMALLQ 287

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 173 TQLRKIMAYSSIAHMGWMTAVL----PYNPTMTLLNLIIYIIMTSTMF----TMFMANSTTTTLSLSHTWNKTPIMTVLI 244
Cdd:PRK06277  288 TDYKRLLAYHAISQGGYVAAGLalgtPLGIVAGIFHAINHVIYKSALFlgagIVSYRTKTSNLRKLGGLLPVMPVVAFMV 367

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1802566705 245 LATLLSMGGLPPLSGFMPKWMIIQEMTKNNSIILPTFMAITALLNLYFYMRLTYSTTL 302
Cdd:PRK06277  368 LCAKLAISGVPPFNGFQSKLMLAQAAMQANMPELAIIMIIVSIGTFVSMMKAFYLIYL 425
ND4 MTH00217
NADH dehydrogenase subunit 4; Provisional
 100-191 1.28e-05

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214462 [Multi-domain]  Cd Length: 482  Bit Score: 46.58  E-value: 1.28e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 100 MALAMKLGMAPFHFWVPEVTQGIPLSSGLIL--------------LTWQKLAPMSvlyQIFPSinlnLILTLSVLSILIG 165
Cdd:MTH00217  214 LSLAIKIPKIPFHIWLPQAHVEAPVAGSVILagvllklggygfirFSWPLLPEAS---EYFSP----LIQTLSLLAIIYG 286

                          90       100
                  ....*....|....*....|....*.
gi 1802566705 166 GWGGLNQTQLRKIMAYSSIAHMGWMT 191
Cdd:MTH00217  287 SLTTCRQVDLKRIIAYSSVAHMGLVT 312
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 55-191 1.44e-05

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 46.73  E-value: 1.44e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  55 ASTKYFLTQSTASmLLMMAVIINLMFSG----------QWTVMKLFNPMASMLMT---MALAMKLGMAPFHFWVPEV--- 118
Cdd:PRK05846  162 AATKFFLYTLLGS-LLMLVAIIYLVVVYynatgtfdiaDLLNLPLPPGVQYWLFLaffIAFAVKMPMFPLHTWLPDAhvq 240

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 119 --TQGIPLSSGLILltwqKLAP---MSVLYQIFPSINLN---LILTLSVLSILIGGWGGLNQTQLRKIMAYSSIAHMGWM 190
Cdd:PRK05846  241 apTAGSVLLAGILL----KMGAyglLRFSLPLFPDASHEfapIIITLGVIAIIYGALVALAQTDIKKLIAYSSISHMGFV 316


                  .
gi 1802566705 191 T 191
Cdd:PRK05846  317 T 317
PRK12662 PRK12662
putative monovalent cation/H+ antiporter subunit D; Reviewed
 152-342 1.91e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 183662 [Multi-domain]  Cd Length: 492  Bit Score: 43.18  E-value: 1.91e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 152 NLILTLSVLSILIGGWGGLNQTQLRKIMAYSSIAHMGWMTAVLPYNPTMTLLNLIIYIIMTSTMFT-MFMAN-------S 223
Cdd:PRK12662  280 NVFMILAALAIVFGSVLAILSKDIKRIFAYSSISHIGYIILAVSLNTYYGLAAAVAYIVNHSIVKSaLFMVSgsisyhfG 359

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 224 TTTTLSLSHTWNKTPIMTVLILATLLSMGGLPPLSGFMPKWMIIQEMTKNNSIILPTFMAITALLNLYFYMRLTYSTTLT 303
Cdd:PRK12662  360 TTKLEDCLNLWKSMPKITLAFVLLSLSLIGMPPTSGFVAKWYILDAFIKSNAWIGLVVLLVGSGLSVIYVWKIVEALYFE 439

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1802566705 304 MfPSTNNMKMKWQFPLMKKMTFLPTMVVLSTMMLPLTPM 342
Cdd:PRK12662  440 S-RMVESKANDKAFKTPNAMVLCIWIMAILSIIVGIYPI 477
PRK12665 PRK12665
putative monovalent cation/H+ antiporter subunit D; Reviewed
 97-291 6.73e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237165 [Multi-domain]  Cd Length: 521  Bit Score: 41.49  E-value: 6.73e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  97 LMTMALAMKLGMAPFHFWVPEvtqGIPLSSGLI------LLTwqKLAPMSVLYQ---IFPSINLN-LILTLSVLSILIGG 166
Cdd:PRK12665  214 VLLVAFGIKAAVFPLSFWLPD---SYPTAPAPVtavfagLLT--KVGVYAIIRThtlLFPGGGLDtLLMVVALLTMVVGI 288

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 167 WGGLNQTQLRKIMAYSSIAHMGWMTAVLPYNPTMTLLNLIIYI---IMTSTmfTMFMANSTTTTLSLSHTWNK------- 236
Cdd:PRK12665  289 LGAIAQSDIKRLLSFTLVSHIGYMVFGIALSTVAGLSGAIYYVahhITVQT--TLFLVVGLIERQAGSSSLRRlgglaka 366

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1802566705 237 TPIMTVLILATLLSMGGLPPLSGFMPKWMIIQEMTKNNSI---ILPTFMAITALLNLY 291
Cdd:PRK12665  367 SPLLAVLFFVPALNLGGIPPFSGFIGKVALLEAGAEDGTWlawALVAGGVVTSLLTLY 424
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 28-190 9.02e-04

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 40.89  E-value: 9.02e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  28 LVWIGFEMNMLaIIPIMMKNHNPRAT-EASTKYFLTQSTASMLLMMAVIINLMFSGQ--------WTVM----KLFNP-- 92
Cdd:PRK08676  126 LFWIFAELTTV-FSAMLIAILSARENiDAALKYIFIASTAMIFAFIGLIFLFSLTRQalgtgtlnWTELaahaSLLSPsv 204

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  93 --MASMLMTMALAMKLGMAPFHFWVPEVTQGIP-----LSSGLIL-LTWQKLAPMSVLY---QIFPSINlNLILTLSVLS 161
Cdd:PRK08676  205 lgASFLFIFIGFLAKSGLVPFHTWLPAAYAKAPsvvsaLLSGTVLnIGIYGILRLSALLrqsGAAEQFS-NVLIGLGIFS 283

                         170       180
                  ....*....|....*....|....*....
gi 1802566705 162 ILIGGWGGLNQTQLRKIMAYSSIAHMGWM 190
Cdd:PRK08676  284 IAVAAFSMLSQRNLKKLIAFSSIEHMGLM 312
ND2 MTH00091
NADH dehydrogenase subunit 2; Provisional
 97-317 3.84e-03

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177154  Cd Length: 273  Bit Score: 38.31  E-value: 3.84e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  97 LMTMALAMKLGMAPFHFWVPEVTQGIPLSSGLILLTWQKLAPMSVLYQIFPSINLNLILTLSVLSILiggwGGLNQTQLR 176
Cdd:MTH00091   62 FQFLILMMKIGVAPFHFWIFSVTNGLFGWNLMWFLTFQKLPFLLVLLQFFSKNFFFLLLFGLLICFF----QMFLLKSYK 137

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 177 KIMAYSSIAHMGWMTAVLPYNPTMTllnLIIYIIMTSTMFTMFMansttttlslshTWNKTPIMTVLILATLLSMGGLPP 256
Cdd:MTH00091  138 NLLILSSTESFNWLILSFFFSFFNV---FFLFFYYFLLMLFLIP------------KFNNVNKLNFVSWETLLVFMNLPF 202

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1802566705 257 LSGFMPKWMIIQEMTKNNSIILPTFMAITALLNLYFYMRLTYSTTLTMFPSTNNMKMKWQF 317
Cdd:MTH00091  203 SVTFFVKIFSLSEILKVLGFFLLFLLFLMFLSVLSLSFWLVNLSTKLFLMLFKYNKGFFFF 263
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
100-190 4.40e-03

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 38.91  E-value: 4.40e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 100 MALAMKLGMAPFHFWVPE--VTQGIPLSS-------------------GLILLTWQKLAPMsvlyqifpsinlnlILTLS 158
Cdd:PRK06473  213 VGFGIKIPLVPFHTWLPDahVEASTPVSVllagvllklgtygllrfgvGLFPEAWVYLAPW--------------LATWA 278

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1802566705 159 VLSILIGGWGGLNQTQLRKIMAYSSIAHMGWM 190
Cdd:PRK06473  279 VVSVLYGASCAIAQKDMKKMVAYSSIGHMGYI 310
PRK06459 PRK06459
hydrogenase 4 subunit B; Validated
 16-288 4.75e-03

hydrogenase 4 subunit B; Validated


Pssm-ID: 235806 [Multi-domain]  Cd Length: 585  Bit Score: 38.62  E-value: 4.75e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  16 GTIIVMISSHWLLVWIGFEMNMLA---IIPIMMKNHNPRATeastkyFLTQSTASMLLMMA-VIINLMFSGQWTVMKLFN 91
Cdd:PRK06459   84 GMAIVLTSDNYLLFLAGWEIMTIPsyvAIALTKKNKRPAFV------FMAFGELSTVLILAgFAWAFIISGTTNFSYLPS 157

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  92 PMASMLMTMALAMKLGMAPFHF--WVPEVTQGIP------LSSGLILLTWQKLAPMSVLYQIFPSINLNL-ILTLSVLSI 162
Cdd:PRK06459  158 PVPLILASFGFIIKMGMMPFLVseWLPIAHGNAPsnfsaiLSATMTLMGVYGILKMTILTQTIPIGYFGLtILAIGAFSI 237

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 163 LIGGWGGLNQTQLRKIMAYSSIAHMGWMTAVLPYNPTMTLLNLIIYIIMTSTMFT-----------MFMANSTTTTLSLS 231
Cdd:PRK06459  238 LFGALYAYVSENVKGLLAFSTIENNGAILVALGLYMVTKQLITSIEHFSLITVILysfahsvaktgLFLSSGLQEKQSIT 317

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1802566705 232 HTWNKTPIMTVLILATL-LSMGGLPPLSGFMPKWMIIQEMTKnNSIILPTFMAITALL 288
Cdd:PRK06459  318 YSKKIRNRWIELGLTLLaSSLSGLLPNIGGVASWLLLESLFM-FAYVLHNVISILFIV 374
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 55-288 5.41e-03

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 38.47  E-value: 5.41e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  55 ASTKYFLTQSTASMLLMMAVIiNLMFSGQWTVMKL-----------FNPMASMLMTMALAMKLGMAPFHFWVPEV--TQG 121
Cdd:PRK12561  138 AATKFILYTALASIFILVAGL-ALALSGDTFTFDLaelgaksyplaLELLLYAGFLIAFGVKLPIFPLHTWLPDAhgEAS 216

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 122 IPLSSGL--ILLTWQKLAPMSVLYQIFPSINLNLILTLSVLSILIGGWGGLN---QTQLRKIMAYSSIAHMGW----MTA 192
Cdd:PRK12561  217 APVSMILagVLLKMGGYALIRFNVQMLPDAHVYFAPALAILGVVNIIYGALNafaQDNVKRRLAYSSVSHMGFvllgIAA 296

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 193 VLPYNPTMTLLNLIIYIIMTSTMF-----------TMFMANSTTTTlslshtwNKTPIMTVLILATLLSMGGLPPLSGFM 261
Cdd:PRK12561  297 FTDLGISGAMLQMISHGLIAAALFfltgvtyerthTLSIPNMGGLA-------KVMPKTFALFTASSMASLALPGMSGFV 369

                         250       260
                  ....*....|....*....|....*..
gi 1802566705 262 PKWMIIQEMTkNNSIILPTFMAITALL 288
Cdd:PRK12561  370 SELTVFLGIT-SSDVYSSTFRTITILL 395
PRK08667 PRK08667
hydrogenase membrane subunit; Validated
 35-268 5.84e-03

hydrogenase membrane subunit; Validated


Pssm-ID: 236331 [Multi-domain]  Cd Length: 644  Bit Score: 38.56  E-value: 5.84e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  35 MNMLAIIPIMMKNHNPRATEASTKYFLTQSTASMLLMMAVIINLMFSGQWTVMKLFNPMAS-----MLMTMALAMKLGMA 109
Cdd:PRK08667  143 MALSSFFLVMNDYQEEETQRAGIFYFVMTQLSTVFLMLGIIVLFIQTGSFELSPLGASAGIlslvfLLLFLGFGIKAGII 222

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 110 PFHFWVPEVTQGIP-----LSSGLILLTwQKLAPMSVLYQIF-PSINLN-LILTLSVLSILIGGWGGLNQTQLRKIMAYS 182
Cdd:PRK08667  223 PFHKWLPYAHPASPsnvsaLMSGVMLKV-AVYGLVRFLMDVLsPELWWGvLILLAGSISALLGVIYALKEHDLKGLLAYS 301

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 183 SIAHMG--------WMTAVLPYNPTMTLLNL-------IIYIIMTSTMF----TMFMANSTTTTLSLSHTWNKTPIMTVL 243
Cdd:PRK08667  302 SIENIGiilmgiglYVIFGVYGLDTLALLALggalfhsLNHALFKSLLFltagSVVHATGTRNIEKMGGLVKLMPYTSAL 381

                         250       260
                  ....*....|....*....|....*
gi 1802566705 244 ILATLLSMGGLPPLSGFMPKWMIIQ 268
Cdd:PRK08667  382 FLVGAVSIAALPPFNGFASELLLYE 406
PRK07691 PRK07691
putative monovalent cation/H+ antiporter subunit D; Reviewed
 95-296 6.17e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 181085 [Multi-domain]  Cd Length: 496  Bit Score: 38.39  E-value: 6.17e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  95 SMLMTMALAMKLGMAPFHFWVPEVTQGIPLS-SGLI--LLTWQKL-APMSVLYQIF---PSINLNLILTLSVLSILIGGW 167
Cdd:PRK07691  212 AILFLFVFATKAGLFPLYFWLPGSYYAPPIAiAALFgaLLTKVGVyAIARTFTLFFshdTSFTHYLILILALLTIIFGVI 291

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705 168 GGLNQTQLRKIMAYSSIAHMGWMTAVLPYNPTMTLLNLIIYIIMTSTMFTM-FMANSTTTTLSLSHTWNKT-------PI 239
Cdd:PRK07691  292 GAVAYFDIKKIIIYNIMIAVGVILVGVAMMTESGMIGAIYYLIHDMIVKAAlFLLIGIMIKITGTTDLKKMgglikryPV 371

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1802566705 240 MTVLILATLLSMGGLPPLSGFMPKWMIIQEMTKNNSIILPTFMAITALLNLYFYMRL 296
Cdd:PRK07691  372 LGWMFFIAALSLAGIPPLSGFYGKFFIVEGTFEAGFYVSGIIVLLSSLLVLYSVIKI 428
ND4 MTH00014
NADH dehydrogenase subunit 4; Validated
 23-192 9.25e-03

NADH dehydrogenase subunit 4; Validated


Pssm-ID: 214399 [Multi-domain]  Cd Length: 452  Bit Score: 37.80  E-value: 9.25e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  23 SSHWLLVWIGFEMNML-AIIPIMMKNHNPRATEASTKYFLTQSTASMLLMMAVII--------NLMFSGQWTVMKLFNPM 93
Cdd:MTH00014  109 ASNLLMFYIFFEASLIpTLFLILGWGYQPERLQASFYLMIYTVTASLPLLMSILLifytnnslSMLMSSMEPPSIYLMNL 188

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802566705  94 ASMLMTMALAMKLGMAPFHFWVPEVTQGIPLSSGLIL------LTWQKLAPMSVLYQIFPSINLNLILTLSVLSILIGGW 167
Cdd:MTH00014  189 WWLITILAFMVKMPLYTVHLWLPKAHVEAPVAGSMILagillkLGGYGLLRMSSLFMHINKSLSAPFSSISLVGAVITSL 268

                         170       180
                  ....*....|....*....|....*
gi 1802566705 168 GGLNQTQLRKIMAYSSIAHMGWMTA 192
Cdd:MTH00014  269 ICIRQPDLKSLIAYSSVGHMGLMTA 293
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH