|
Name |
Accession |
Description |
Interval |
E-value |
| PRK01117 |
PRK01117 |
adenylosuccinate synthetase; Provisional |
1-428 |
0e+00 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 234904 Cd Length: 430 Bit Score: 810.04 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 1 MAAIVLIGAQWGDEGKGKATDLLGGRLQWVVRYQGGNNAGHTVVLPsGETFALHLIPSGILTRGVNNVIGNGVVVDPGVL 80
Cdd:PRK01117 1 MKNVVVVGTQWGDEGKGKIVDLLSERADVVVRFQGGHNAGHTLVID-GKKYKLHLIPSGILRPGKTCVIGNGVVLDPEAL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 81 LTELSGLEERDVDTTG-LMISADAHLLMPYHVAIDKVTERFLGNKKIGTTGRGIGPCYQDKIARGGVRVADVLDEKILSQ 159
Cdd:PRK01117 80 LKEIDELEARGVDVRErLRISERAHLILPYHRALDKAREKARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPETFAE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 160 KVEAALELKNQILVKIYNRKALEPARVVDEVLAQAEGFSHRIADTRLLLNQALERGETVLLEGSQGTLLDVDHGTYPYVT 239
Cdd:PRK01117 160 KLEENLEYKNFLLTKYYGAEAVDFEEILDEYLEYAERLKPYVTDTSLLLNDALKAGKRVLFEGAQGTLLDIDHGTYPFVT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 240 SSNPTAGGAAVGSGIGPNKITTVLGILKAYTTRVGSGPFPTELFDEWGEYLAKTGGEVGVTTGRARRCGWFDAVIARYAT 319
Cdd:PRK01117 240 SSNTTAGGAATGSGVGPTKIDYVLGIAKAYTTRVGSGPFPTELFDEVGEHLRERGHEFGTTTGRPRRCGWFDAVALRYAV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 320 RVNGITDYFLTKLDVLSSLERVPICVAYEVDGERVDEMPMTQTGFHHAKPIYETMPGWWEDISECRRFEDLPQNAQNYIL 399
Cdd:PRK01117 320 RVNGLTGLALTKLDVLDGLEEIKICVAYELDGKRIDYFPASLEDLARCEPIYEELPGWSESTTGVRSFDDLPENARKYIK 399
|
410 420
....*....|....*....|....*....
gi 1799598060 400 RLEELSGAHISCIGVGPGRDQTIVRRDIL 428
Cdd:PRK01117 400 RIEELTGVPISIISTGPDRDQTIILRDPF 428
|
|
| PurA |
COG0104 |
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is ... |
3-425 |
0e+00 |
|
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is part of the Pathway/BioSystem: Purine biosynthesis
Pssm-ID: 439874 Cd Length: 423 Bit Score: 753.00 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 3 AIVLIGAQWGDEGKGKATDLLGGRLQWVVRYQGGNNAGHTVVLpSGETFALHLIPSGILTRGVNNVIGNGVVVDPGVLLT 82
Cdd:COG0104 1 NVVVVGAQWGDEGKGKIVDLLAERADVVVRFQGGNNAGHTVVV-GGKKFKLHLIPSGILRPGKTCVIGNGVVLDPEALLE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 83 ELSGLEERDVDTTG-LMISADAHLLMPYHVAIDKVTERFLGNKKIGTTGRGIGPCYQDKIARGGVRVADVLDEKILSQKV 161
Cdd:COG0104 80 EIDGLEARGVDVRSrLRISERAHLILPYHRALDKAREEARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPEVLREKL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 162 EAALELKNQILVKIYNRKALEPARVVDEVLAQAEGFSHRIADTRLLLNQALERGETVLLEGSQGTLLDVDHGTYPYVTSS 241
Cdd:COG0104 160 EELLEYKNFLLEKLYGAEPLDFEELLEEYLEYAERLKPYVADTSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSS 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 242 NPTAGGAAVGSGIGPNKITTVLGILKAYTTRVGSGPFPTELFDEWGEYLAKTGGEVGVTTGRARRCGWFDAVIARYATRV 321
Cdd:COG0104 240 NTTAGGACTGSGVGPTKIDRVIGVVKAYTTRVGEGPFPTELFDETGERLRERGHEFGTTTGRPRRCGWLDAVALRYAVRI 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 322 NGITDYFLTKLDVLSSLERVPICVAYEVDGERVDEMPMTQTGFHHAKPIYETMPGWWEDISECRRFEDLPQNAQNYILRL 401
Cdd:COG0104 320 NGLTGLALTKLDVLDGLDEIKVCVAYELDGERIDEFPASLEDLARCEPVYEELPGWKEDISGIRSFEDLPENARAYVERI 399
|
410 420
....*....|....*....|....
gi 1799598060 402 EELSGAHISCIGVGPGRDQTIVRR 425
Cdd:COG0104 400 EELLGVPISIVSVGPDREQTIVRR 423
|
|
| Adenylsucc_synt |
pfam00709 |
Adenylosuccinate synthetase; |
5-422 |
0e+00 |
|
Adenylosuccinate synthetase;
Pssm-ID: 459912 Cd Length: 417 Bit Score: 715.28 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 5 VLIGAQWGDEGKGKATDLLGGRLQWVVRYQGGNNAGHTVVLpSGETFALHLIPSGILTRGVNNVIGNGVVVDPGVLLTEL 84
Cdd:pfam00709 1 VVVGAQWGDEGKGKIVDLLAEDADVVVRFQGGNNAGHTVVV-DGKKYKLHLLPSGILNPGKTNVIGNGVVIDPPALLEEI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 85 SGLEERDVDTTG-LMISADAHLLMPYHVAIDKVTERFLGNKKIGTTGRGIGPCYQDKIARGGVRVADVLDEKILSQKVEA 163
Cdd:pfam00709 80 EELEERGIDVPDrLFISDRAHLILPYHKALDGLREEARGKKKIGTTGRGIGPAYSDKAARRGIRVGDLLDPEVFREKLEA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 164 ALELKNQILVKIYNrKALEPARVVDEVLAQAEGFSHRIADTRLLLNQALERGETVLLEGSQGTLLDVDHGTYPYVTSSNP 243
Cdd:pfam00709 160 LLELKNKLLEKLYG-EPLDVEEELEELLEYAERLKPYVVDTSYFLNKALKEGKKILFEGAQGTLLDIDHGTYPYVTSSNT 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 244 TAGGAAVGSGIGPNKITTVLGILKAYTTRVGSGPFPTELFDEWGEYLAKTGGEVGVTTGRARRCGWFDAVIARYATRVNG 323
Cdd:pfam00709 239 TAGGACTGLGIGPTKIDEVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGATTGRPRRCGWLDLVALRYAVRING 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 324 ITDYFLTKLDVLSSLERVPICVAYEVDGERVDEMPMTQTGFHHAKPIYETMPGWWEDISECRRFEDLPQNAQNYILRLEE 403
Cdd:pfam00709 319 VTGLALTKLDVLDGLDEIKVCVAYELDGKRIDYFPADLEDLEKVEPVYETLPGWKEDISGVRSFEDLPENARKYVEFIEE 398
|
410
....*....|....*....
gi 1799598060 404 LSGAHISCIGVGPGRDQTI 422
Cdd:pfam00709 399 LLGVPIKIISVGPDREQTI 417
|
|
| Adenylsucc_synt |
smart00788 |
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine ... |
3-423 |
0e+00 |
|
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine biosynthesis, by catalyzing the GTP-dependent conversion of IMP and aspartic acid to AMP. Adenylosuccinate synthetase has been characterized from various sources ranging from Escherichia coli (gene purA) to vertebrate tissues. In vertebrates, two isozymes are present - one involved in purine biosynthesis and the other in the purine nucleotide cycle. The crystal structure of adenylosuccinate synthetase from E. coli reveals that the dominant structural element of each monomer of the homodimer is a central beta-sheet of 10 strands. The first nine strands of the sheet are mutually parallel with right-handed crossover connections between the strands. The 10th strand is antiparallel with respect to the first nine strands. In addition, the enzyme has two antiparallel beta-sheets, comprised of two strands and three strands each, 11 alpha-helices and two short 3/10-helices. Further, it has been suggested that the similarities in the GTP-binding domains of the synthetase and the p21ras protein are an example of convergent evolution of two distinct families of GTP-binding proteins. Structures of adenylosuccinate synthetase from Triticum aestivum and Arabidopsis thaliana when compared with the known structures from E. coli reveals that the overall fold is very similar to that of the E. coli protein.
Pssm-ID: 197875 Cd Length: 417 Bit Score: 674.58 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 3 AIVLIGAQWGDEGKGKATDLLGGRLQWVVRYQGGNNAGHTVVLpSGETFALHLIPSGILTRGVNNVIGNGVVVDPGVLLT 82
Cdd:smart00788 1 VVVVVGAQWGDEGKGKIVDYLAEKADVVVRFQGGNNAGHTVVV-NGKKYKLHLLPSGILNPNKKNVIGNGVVIDPEALFK 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 83 ELSGLEERDVDTTG-LMISADAHLLMPYHVAIDKVTErflgNKKIGTTGRGIGPCYQDKIARGGVRVADVLDEKILSQKV 161
Cdd:smart00788 80 EIEELEAKGVDVKDrLFISDRAHLILPYHIALDKARE----KARIGTTGRGIGPAYEDKVARRGIRVGDLFDEEVLREKL 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 162 EAALELKNQILVKIYNRKALEPARVVDEVLAQAEGFSHRIADTRLLLNQALERGETVLLEGSQGTLLDVDHGTYPYVTSS 241
Cdd:smart00788 156 EELLDYKNFLLKKLYGAEPVDVEEILEELLEYAERLRPYVTDVSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSS 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 242 NPTAGGAAVGSGIGPNKITTVLGILKAYTTRVGSGPFPTELFDEWGEYLAKTGGEVGVTTGRARRCGWFDAVIARYATRV 321
Cdd:smart00788 236 NTTAGGAATGAGIGPTRIDRVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGTTTGRPRRCGWFDAVLLRYAVRI 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 322 NGITDYFLTKLDVLSSLERVPICVAYEVDGERVDEMPMTQTGFHHAKPIYETMPGWWEDISECRRFEDLPQNAQNYILRL 401
Cdd:smart00788 316 NGITGLALTKLDVLDGLDEIKVCVAYKLDGKIIDYFPADLEDLERCEPIYEELPGWKEDTTGVRSYEDLPENAKKYIERI 395
|
410 420
....*....|....*....|..
gi 1799598060 402 EELSGAHISCIGVGPGRDQTIV 423
Cdd:smart00788 396 EELVGVPVSIISTGPDREQTIV 417
|
|
| purA |
TIGR00184 |
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, ... |
5-428 |
0e+00 |
|
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 272949 Cd Length: 425 Bit Score: 527.11 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 5 VLIGAQWGDEGKGKATDLLGGRLQWVVRYQGGNNAGHTVVLpSGETFALHLIPSGILTRGVNNVIGNGVVVDPGVLLTEL 84
Cdd:TIGR00184 1 VVVGGQWGDEGKGKIVDLLADKPDIVARYQGGHNAGHTIVI-DGVKYGLHLIPSGFLYPDAKLLIGNGVVVDPEVLLKEM 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 85 SGLEERDVDTTG-LMISADAHLLMPYHVAIDKVTERFLGNKKIGTTGRGIGPCYQDKIARGGVRVADVLDEKILSQKVEA 163
Cdd:TIGR00184 80 EYLEKRGISVRDrLFVSYRCHLILPYHKKLDKAREKSKLAKKIGTTGKGIGPAYEDKVARSGLRVGDLLDDEAFAEKAKN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 164 ALELKNQILVKIYNRKALEPARVVDEVLAQAEGFSHRIADTRLLLNQALERGETVLLEGSQGTLLDVDHGTYPYVTSSNP 243
Cdd:TIGR00184 160 ILEYLNEQLVKYYKDEGVDYEKKLDEYMKYAEELKPFVVDVSVELNEALDEGEKVLFEGAQGTMLDIDYGTYPYVTSSNT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 244 TAGGAAVGSGIGPNKITTVLGILKAYTTRVGSGPFPTELFDEWGEYLAKTGGEVGVTTGRARRCGWFDAVIARYATRVNG 323
Cdd:TIGR00184 240 TAGGVATGVGIGPTKVDEVIGVFKAYTTRVGAGPFPTELSDEEGEKLGTKGAEFGTTTGRRRRCGWFDLVAARYACRLNG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 324 ITDYFLTKLDVLSSLERVPICVAYEVDGERVDEMPMTQTGFHHAKPIYETMPGWWEDISECRRFEDLPQNAQNYILRLEE 403
Cdd:TIGR00184 320 ATQLALTKLDVLDGIDEIKVCVAYRMKGEILELFPLDLKDLKGVEPIYETLPGWDKECTGVTEYSDLPENAKKYIERIEE 399
|
410 420
....*....|....*....|....*
gi 1799598060 404 LSGAHISCIGVGPGRDQTIVRRDIL 428
Cdd:TIGR00184 400 LTGVPVTIISTGPEREQTIDLRKEL 424
|
|
| AdSS |
cd03108 |
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in ... |
3-423 |
5.78e-164 |
|
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the r-phosphate group of GTP is transferred to the 6-oxygen atom of IMP. An aspartate then displaces this 6-phosphate group to form the product adenylosuccinate. Because of its critical role in purine biosynthesis, AdSS is a target of antibiotics, herbicides and antitumor drugs.
Pssm-ID: 349762 Cd Length: 316 Bit Score: 463.51 E-value: 5.78e-164
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 3 AIVLIGAQWGDEGKGKATDLLGGRLQWVVRYQGGNNAGHTVVLpSGETFALHLIPSGILTRGVNNVIGNGVVVDPGVLLT 82
Cdd:cd03108 2 VTVVVGAQWGDEGKGKIVDYLAEKADIVVRFQGGNNAGHTVVV-NGKKYKLHLLPSGILNPNATCVIGNGVVIDPPALFE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 83 ELSGLEERDVDTTG-LMISADAHLLMPYHVAIDKVTERFLGNKKIGTTGRGIGPCYQDKIARGGVRVADvldekilsqkv 161
Cdd:cd03108 81 EIEELEKKGIDVKGrLLISDRAHLVFPYHQELDGLEEKERGGKKIGTTKRGIGPAYADKAARTGIRVGD----------- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 162 eaalelknqilvkiynrkaleparvvdevlaqaegfsHRIADTRLLLNQALERGETVLLEGSQGTLLDVDHGTYPYVTSS 241
Cdd:cd03108 150 -------------------------------------PYVVDTVELLNEALKAGKKVLFEGAQGTLLDIDFGTYPYVTSS 192
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 242 NPTAGGAAVGSGIGPNKITTVLGILKAYTTRVGSGPFPTELFDEWGEYLAKTGGEVGVTTGRARRCGWFDAVIARYATRV 321
Cdd:cd03108 193 NTTAGGVCTGLGIPPRRVDRVIGVVKAYTTRVGSGPFPTELFDEEGEKLRELGHEYGTTTGRPRRCGWLDLVALRYAVRI 272
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 322 NGITDYFLTKLDVlsslervpicvayevdgervdempmtqtgfhhakpiyetmpgwwedisecrrfedlpqNAQNYILRL 401
Cdd:cd03108 273 NGLTELALTKLDV----------------------------------------------------------NAQKYIERI 294
|
410 420
....*....|....*....|..
gi 1799598060 402 EELSGAHISCIGVGPGRDQTIV 423
Cdd:cd03108 295 EELLGVPITYISVGPDREQTII 316
|
|
| amino_Aden_PurZ |
NF038379 |
succino-amino-deoxyadenylate synthase PurZ; |
3-323 |
5.39e-26 |
|
succino-amino-deoxyadenylate synthase PurZ;
Pssm-ID: 468496 Cd Length: 292 Bit Score: 106.69 E-value: 5.39e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 3 AIVLIGAQWGDEGKGKATDLLGGRLQWVVRYQ-GGNNAGHTVVLPSGETFALHLIPSGILTRGVNNV-IGNGVVVDPGVL 80
Cdd:NF038379 1 VDVVVDGQFGSTGKGLIAGYLAERAAPDVVVRaAGPNAGHTYIDDEGRKFVHRMLPNGIVSPPLKQVlIGPGSEIDLEVL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 81 LTELSGLEERDVDT-TGLMISADAHLLMPYHvaidKVTERFLGNKKIGTTGRGIGPCYQDKIARGGVRVADVLDEKILSQ 159
Cdd:NF038379 81 REEIEELEDAGHDVgKRLLIHEQATVIELHK----HVEEEAGPMTKIGSTKKGIGAARAAKIRRNPSTLGDAEGDFGEGA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 160 KVEAALELknqilvkiynrkalePARVVDEVLAQaegfshriadtrlllnQALERGETVLLEGSQGTLLDVDHGTYPYVT 239
Cdd:NF038379 157 VRDQPWEI---------------AERVVDNALYD----------------FALQAAERIQIEGTQGYSLGLHAGFYPYCT 205
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 240 SSNPTAGGAAVGSGIGPN--KITTVLGILKAYTTRVG-----SGPFPTEL-FDEWGEYLAKTggevgVTTGRARRCGWFD 311
Cdd:NF038379 206 SRDCTPADFLADAGIPLPnvDAFKVVGTARTYPIRVAgwsgnSYPDQGETtWEELGLPEELT-----TVTKKVRRVGTFS 280
|
330
....*....|..
gi 1799598060 312 AVIARYATRVNG 323
Cdd:NF038379 281 AEQVREAVQANG 292
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK01117 |
PRK01117 |
adenylosuccinate synthetase; Provisional |
1-428 |
0e+00 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 234904 Cd Length: 430 Bit Score: 810.04 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 1 MAAIVLIGAQWGDEGKGKATDLLGGRLQWVVRYQGGNNAGHTVVLPsGETFALHLIPSGILTRGVNNVIGNGVVVDPGVL 80
Cdd:PRK01117 1 MKNVVVVGTQWGDEGKGKIVDLLSERADVVVRFQGGHNAGHTLVID-GKKYKLHLIPSGILRPGKTCVIGNGVVLDPEAL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 81 LTELSGLEERDVDTTG-LMISADAHLLMPYHVAIDKVTERFLGNKKIGTTGRGIGPCYQDKIARGGVRVADVLDEKILSQ 159
Cdd:PRK01117 80 LKEIDELEARGVDVRErLRISERAHLILPYHRALDKAREKARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPETFAE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 160 KVEAALELKNQILVKIYNRKALEPARVVDEVLAQAEGFSHRIADTRLLLNQALERGETVLLEGSQGTLLDVDHGTYPYVT 239
Cdd:PRK01117 160 KLEENLEYKNFLLTKYYGAEAVDFEEILDEYLEYAERLKPYVTDTSLLLNDALKAGKRVLFEGAQGTLLDIDHGTYPFVT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 240 SSNPTAGGAAVGSGIGPNKITTVLGILKAYTTRVGSGPFPTELFDEWGEYLAKTGGEVGVTTGRARRCGWFDAVIARYAT 319
Cdd:PRK01117 240 SSNTTAGGAATGSGVGPTKIDYVLGIAKAYTTRVGSGPFPTELFDEVGEHLRERGHEFGTTTGRPRRCGWFDAVALRYAV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 320 RVNGITDYFLTKLDVLSSLERVPICVAYEVDGERVDEMPMTQTGFHHAKPIYETMPGWWEDISECRRFEDLPQNAQNYIL 399
Cdd:PRK01117 320 RVNGLTGLALTKLDVLDGLEEIKICVAYELDGKRIDYFPASLEDLARCEPIYEELPGWSESTTGVRSFDDLPENARKYIK 399
|
410 420
....*....|....*....|....*....
gi 1799598060 400 RLEELSGAHISCIGVGPGRDQTIVRRDIL 428
Cdd:PRK01117 400 RIEELTGVPISIISTGPDRDQTIILRDPF 428
|
|
| PurA |
COG0104 |
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is ... |
3-425 |
0e+00 |
|
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is part of the Pathway/BioSystem: Purine biosynthesis
Pssm-ID: 439874 Cd Length: 423 Bit Score: 753.00 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 3 AIVLIGAQWGDEGKGKATDLLGGRLQWVVRYQGGNNAGHTVVLpSGETFALHLIPSGILTRGVNNVIGNGVVVDPGVLLT 82
Cdd:COG0104 1 NVVVVGAQWGDEGKGKIVDLLAERADVVVRFQGGNNAGHTVVV-GGKKFKLHLIPSGILRPGKTCVIGNGVVLDPEALLE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 83 ELSGLEERDVDTTG-LMISADAHLLMPYHVAIDKVTERFLGNKKIGTTGRGIGPCYQDKIARGGVRVADVLDEKILSQKV 161
Cdd:COG0104 80 EIDGLEARGVDVRSrLRISERAHLILPYHRALDKAREEARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPEVLREKL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 162 EAALELKNQILVKIYNRKALEPARVVDEVLAQAEGFSHRIADTRLLLNQALERGETVLLEGSQGTLLDVDHGTYPYVTSS 241
Cdd:COG0104 160 EELLEYKNFLLEKLYGAEPLDFEELLEEYLEYAERLKPYVADTSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSS 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 242 NPTAGGAAVGSGIGPNKITTVLGILKAYTTRVGSGPFPTELFDEWGEYLAKTGGEVGVTTGRARRCGWFDAVIARYATRV 321
Cdd:COG0104 240 NTTAGGACTGSGVGPTKIDRVIGVVKAYTTRVGEGPFPTELFDETGERLRERGHEFGTTTGRPRRCGWLDAVALRYAVRI 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 322 NGITDYFLTKLDVLSSLERVPICVAYEVDGERVDEMPMTQTGFHHAKPIYETMPGWWEDISECRRFEDLPQNAQNYILRL 401
Cdd:COG0104 320 NGLTGLALTKLDVLDGLDEIKVCVAYELDGERIDEFPASLEDLARCEPVYEELPGWKEDISGIRSFEDLPENARAYVERI 399
|
410 420
....*....|....*....|....
gi 1799598060 402 EELSGAHISCIGVGPGRDQTIVRR 425
Cdd:COG0104 400 EELLGVPISIVSVGPDREQTIVRR 423
|
|
| Adenylsucc_synt |
pfam00709 |
Adenylosuccinate synthetase; |
5-422 |
0e+00 |
|
Adenylosuccinate synthetase;
Pssm-ID: 459912 Cd Length: 417 Bit Score: 715.28 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 5 VLIGAQWGDEGKGKATDLLGGRLQWVVRYQGGNNAGHTVVLpSGETFALHLIPSGILTRGVNNVIGNGVVVDPGVLLTEL 84
Cdd:pfam00709 1 VVVGAQWGDEGKGKIVDLLAEDADVVVRFQGGNNAGHTVVV-DGKKYKLHLLPSGILNPGKTNVIGNGVVIDPPALLEEI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 85 SGLEERDVDTTG-LMISADAHLLMPYHVAIDKVTERFLGNKKIGTTGRGIGPCYQDKIARGGVRVADVLDEKILSQKVEA 163
Cdd:pfam00709 80 EELEERGIDVPDrLFISDRAHLILPYHKALDGLREEARGKKKIGTTGRGIGPAYSDKAARRGIRVGDLLDPEVFREKLEA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 164 ALELKNQILVKIYNrKALEPARVVDEVLAQAEGFSHRIADTRLLLNQALERGETVLLEGSQGTLLDVDHGTYPYVTSSNP 243
Cdd:pfam00709 160 LLELKNKLLEKLYG-EPLDVEEELEELLEYAERLKPYVVDTSYFLNKALKEGKKILFEGAQGTLLDIDHGTYPYVTSSNT 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 244 TAGGAAVGSGIGPNKITTVLGILKAYTTRVGSGPFPTELFDEWGEYLAKTGGEVGVTTGRARRCGWFDAVIARYATRVNG 323
Cdd:pfam00709 239 TAGGACTGLGIGPTKIDEVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGATTGRPRRCGWLDLVALRYAVRING 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 324 ITDYFLTKLDVLSSLERVPICVAYEVDGERVDEMPMTQTGFHHAKPIYETMPGWWEDISECRRFEDLPQNAQNYILRLEE 403
Cdd:pfam00709 319 VTGLALTKLDVLDGLDEIKVCVAYELDGKRIDYFPADLEDLEKVEPVYETLPGWKEDISGVRSFEDLPENARKYVEFIEE 398
|
410
....*....|....*....
gi 1799598060 404 LSGAHISCIGVGPGRDQTI 422
Cdd:pfam00709 399 LLGVPIKIISVGPDREQTI 417
|
|
| Adenylsucc_synt |
smart00788 |
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine ... |
3-423 |
0e+00 |
|
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine biosynthesis, by catalyzing the GTP-dependent conversion of IMP and aspartic acid to AMP. Adenylosuccinate synthetase has been characterized from various sources ranging from Escherichia coli (gene purA) to vertebrate tissues. In vertebrates, two isozymes are present - one involved in purine biosynthesis and the other in the purine nucleotide cycle. The crystal structure of adenylosuccinate synthetase from E. coli reveals that the dominant structural element of each monomer of the homodimer is a central beta-sheet of 10 strands. The first nine strands of the sheet are mutually parallel with right-handed crossover connections between the strands. The 10th strand is antiparallel with respect to the first nine strands. In addition, the enzyme has two antiparallel beta-sheets, comprised of two strands and three strands each, 11 alpha-helices and two short 3/10-helices. Further, it has been suggested that the similarities in the GTP-binding domains of the synthetase and the p21ras protein are an example of convergent evolution of two distinct families of GTP-binding proteins. Structures of adenylosuccinate synthetase from Triticum aestivum and Arabidopsis thaliana when compared with the known structures from E. coli reveals that the overall fold is very similar to that of the E. coli protein.
Pssm-ID: 197875 Cd Length: 417 Bit Score: 674.58 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 3 AIVLIGAQWGDEGKGKATDLLGGRLQWVVRYQGGNNAGHTVVLpSGETFALHLIPSGILTRGVNNVIGNGVVVDPGVLLT 82
Cdd:smart00788 1 VVVVVGAQWGDEGKGKIVDYLAEKADVVVRFQGGNNAGHTVVV-NGKKYKLHLLPSGILNPNKKNVIGNGVVIDPEALFK 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 83 ELSGLEERDVDTTG-LMISADAHLLMPYHVAIDKVTErflgNKKIGTTGRGIGPCYQDKIARGGVRVADVLDEKILSQKV 161
Cdd:smart00788 80 EIEELEAKGVDVKDrLFISDRAHLILPYHIALDKARE----KARIGTTGRGIGPAYEDKVARRGIRVGDLFDEEVLREKL 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 162 EAALELKNQILVKIYNRKALEPARVVDEVLAQAEGFSHRIADTRLLLNQALERGETVLLEGSQGTLLDVDHGTYPYVTSS 241
Cdd:smart00788 156 EELLDYKNFLLKKLYGAEPVDVEEILEELLEYAERLRPYVTDVSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSS 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 242 NPTAGGAAVGSGIGPNKITTVLGILKAYTTRVGSGPFPTELFDEWGEYLAKTGGEVGVTTGRARRCGWFDAVIARYATRV 321
Cdd:smart00788 236 NTTAGGAATGAGIGPTRIDRVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGTTTGRPRRCGWFDAVLLRYAVRI 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 322 NGITDYFLTKLDVLSSLERVPICVAYEVDGERVDEMPMTQTGFHHAKPIYETMPGWWEDISECRRFEDLPQNAQNYILRL 401
Cdd:smart00788 316 NGITGLALTKLDVLDGLDEIKVCVAYKLDGKIIDYFPADLEDLERCEPIYEELPGWKEDTTGVRSYEDLPENAKKYIERI 395
|
410 420
....*....|....*....|..
gi 1799598060 402 EELSGAHISCIGVGPGRDQTIV 423
Cdd:smart00788 396 EELVGVPVSIISTGPDREQTIV 417
|
|
| purA |
TIGR00184 |
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, ... |
5-428 |
0e+00 |
|
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 272949 Cd Length: 425 Bit Score: 527.11 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 5 VLIGAQWGDEGKGKATDLLGGRLQWVVRYQGGNNAGHTVVLpSGETFALHLIPSGILTRGVNNVIGNGVVVDPGVLLTEL 84
Cdd:TIGR00184 1 VVVGGQWGDEGKGKIVDLLADKPDIVARYQGGHNAGHTIVI-DGVKYGLHLIPSGFLYPDAKLLIGNGVVVDPEVLLKEM 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 85 SGLEERDVDTTG-LMISADAHLLMPYHVAIDKVTERFLGNKKIGTTGRGIGPCYQDKIARGGVRVADVLDEKILSQKVEA 163
Cdd:TIGR00184 80 EYLEKRGISVRDrLFVSYRCHLILPYHKKLDKAREKSKLAKKIGTTGKGIGPAYEDKVARSGLRVGDLLDDEAFAEKAKN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 164 ALELKNQILVKIYNRKALEPARVVDEVLAQAEGFSHRIADTRLLLNQALERGETVLLEGSQGTLLDVDHGTYPYVTSSNP 243
Cdd:TIGR00184 160 ILEYLNEQLVKYYKDEGVDYEKKLDEYMKYAEELKPFVVDVSVELNEALDEGEKVLFEGAQGTMLDIDYGTYPYVTSSNT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 244 TAGGAAVGSGIGPNKITTVLGILKAYTTRVGSGPFPTELFDEWGEYLAKTGGEVGVTTGRARRCGWFDAVIARYATRVNG 323
Cdd:TIGR00184 240 TAGGVATGVGIGPTKVDEVIGVFKAYTTRVGAGPFPTELSDEEGEKLGTKGAEFGTTTGRRRRCGWFDLVAARYACRLNG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 324 ITDYFLTKLDVLSSLERVPICVAYEVDGERVDEMPMTQTGFHHAKPIYETMPGWWEDISECRRFEDLPQNAQNYILRLEE 403
Cdd:TIGR00184 320 ATQLALTKLDVLDGIDEIKVCVAYRMKGEILELFPLDLKDLKGVEPIYETLPGWDKECTGVTEYSDLPENAKKYIERIEE 399
|
410 420
....*....|....*....|....*
gi 1799598060 404 LSGAHISCIGVGPGRDQTIVRRDIL 428
Cdd:TIGR00184 400 LTGVPVTIISTGPEREQTIDLRKEL 424
|
|
| PTZ00350 |
PTZ00350 |
adenylosuccinate synthetase; Provisional |
5-424 |
3.50e-176 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 240376 Cd Length: 436 Bit Score: 499.17 E-value: 3.50e-176
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 5 VLIGAQWGDEGKGKATDLLGGRLQWVVRYQGGNNAGHTVVLpSGETFALHLIPSGILTRGVNNVIGNGVVVDPGVLLTEL 84
Cdd:PTZ00350 16 VILGAQWGDEGKGKLVDILSEKADIVARFNGGANAGHTIVV-DGKKYALHLLPCGILYPNCINVLGNGVVIHLPSLLEEI 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 85 SGLEERDVDTTG-LMISADAHLLMPYHVAID--KVTERFLGNKKIGTTGRGIGPCYQDKIARGGVRVADVLDEKILSQKV 161
Cdd:PTZ00350 95 EQLTKKGINLLGrLYISDRAHLVFDLHQAIDgiQESEKGKGGTQIGTTKRGIGPCYSTKASRTGLRVGDLLNFETFEKKY 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 162 EAALE-LKNQILVKIYNRKA-LEPARVVDEVLAqaegfsHRIADTRLLLNQALERGETVLLEGSQGTLLDVDHGTYPYVT 239
Cdd:PTZ00350 175 RKLVEkLQEQYNIEEYDAEEeLERYKGYAEKLK------DMIVDTVYFMNKAIKEGKRVLVEGANATMLDIDFGTYPYVT 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 240 SSNPTAGGAAVGSGIGPNKITTVLGILKAYTTRVGSGPFPTELFDEWGEYLAKTGGEVGVTTGRARRCGWFDAVIARYAT 319
Cdd:PTZ00350 249 SSNTTVGGVCTGLGIPPNAIILVIGVVKAYTTRVGEGPFPTELFDENGDYLRKKGHEYGTTTGRPRRCGWLDIPALRYVQ 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 320 RVNGITDYFLTKLDVLSSLERVPICVAYEVDGERV--DEMPMTQTGFHHAKPIYETMPGWWEDISECRRFEDLPQNAQNY 397
Cdd:PTZ00350 329 MINGFDSINLTKLDVLSGLKEIKICVNYKNKGTGLeiGRYPSSIEELEEYEPVYETMPGWKTDISKCKTFEELPENAQKY 408
|
410 420
....*....|....*....|....*..
gi 1799598060 398 ILRLEELSGAHISCIGVGPGRDQTIVR 424
Cdd:PTZ00350 409 VLFIEELLGVPIVWIGVGPNRENMIVK 435
|
|
| PLN02513 |
PLN02513 |
adenylosuccinate synthase |
5-425 |
2.35e-173 |
|
adenylosuccinate synthase
Pssm-ID: 178129 Cd Length: 427 Bit Score: 491.85 E-value: 2.35e-173
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 5 VLIGAQWGDEGKGKATDLLGGRLQWVVRYQGGNNAGHTVVLPSGETFALHLIPSGILTRGVNNVIGNGVVVDPGVLLTEL 84
Cdd:PLN02513 6 AVLGTQWGDEGKGKLVDILAQHFDIVARCQGGANAGHTIYNDEGKKFALHLVPSGILNEKTTCVIGNGVVVHLPGLFEEI 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 85 SGLEERDVDTTG-LMISADAHLLMPYHVAIDKVTERFLGNKKIGTTGRGIGPCYQDKIARGGVRVADVLDEKILSQKVEA 163
Cdd:PLN02513 86 DGLESNGVSCEGrLLVSDRAHLLFDFHQEVDGLREAELAGSKIGTTKRGIGPAYSSKATRNGLRVGDLRHMDTFAEKLRE 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 164 ALELKNQILvkiynrKALE-PARVVDEVLAQAEGFSHR----IADTRLLLNQALERGETVLLEGSQGTLLDVDHGTYPYV 238
Cdd:PLN02513 166 LLADAAARF------EGFEyDASMVEEEVEAYKKFAERlepfITDTVHYLNEAIQAGKKILVEGAQATMLDIDFGTYPFV 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 239 TSSNPTAGGAAVGSGIGPNKITTVLGILKAYTTRVGSGPFPTELFDEWGEYLAKTGGEVGVTTGRARRCGWFDAVIARYA 318
Cdd:PLN02513 240 TSSNPSAGGICTGLGIAPRKLGDIIGVVKAYTTRVGSGPFPTELFGELGDLLREAGQEFGTTTGRPRRCGWLDIVALKYS 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 319 TRVNGITDYFLTKLDVLSSLERVPICVAYE-VDGERVDEMPMTQTGFHHAKPIYETMPGWWEDISECRRFEDLPQNAQNY 397
Cdd:PLN02513 320 CQINGFTSLNLTKLDVLSGLPEIKIGVAYKtPDGKVVKSFPADLDTLEQVEVVYEVLPGWQEDISSVRNYDDLPAAAQAY 399
|
410 420
....*....|....*....|....*...
gi 1799598060 398 ILRLEELSGAHISCIGVGPGRDQTIVRR 425
Cdd:PLN02513 400 VERIEELVGVPVHYIGVGPGRDALIVKP 427
|
|
| AdSS |
cd03108 |
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in ... |
3-423 |
5.78e-164 |
|
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the r-phosphate group of GTP is transferred to the 6-oxygen atom of IMP. An aspartate then displaces this 6-phosphate group to form the product adenylosuccinate. Because of its critical role in purine biosynthesis, AdSS is a target of antibiotics, herbicides and antitumor drugs.
Pssm-ID: 349762 Cd Length: 316 Bit Score: 463.51 E-value: 5.78e-164
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 3 AIVLIGAQWGDEGKGKATDLLGGRLQWVVRYQGGNNAGHTVVLpSGETFALHLIPSGILTRGVNNVIGNGVVVDPGVLLT 82
Cdd:cd03108 2 VTVVVGAQWGDEGKGKIVDYLAEKADIVVRFQGGNNAGHTVVV-NGKKYKLHLLPSGILNPNATCVIGNGVVIDPPALFE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 83 ELSGLEERDVDTTG-LMISADAHLLMPYHVAIDKVTERFLGNKKIGTTGRGIGPCYQDKIARGGVRVADvldekilsqkv 161
Cdd:cd03108 81 EIEELEKKGIDVKGrLLISDRAHLVFPYHQELDGLEEKERGGKKIGTTKRGIGPAYADKAARTGIRVGD----------- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 162 eaalelknqilvkiynrkaleparvvdevlaqaegfsHRIADTRLLLNQALERGETVLLEGSQGTLLDVDHGTYPYVTSS 241
Cdd:cd03108 150 -------------------------------------PYVVDTVELLNEALKAGKKVLFEGAQGTLLDIDFGTYPYVTSS 192
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 242 NPTAGGAAVGSGIGPNKITTVLGILKAYTTRVGSGPFPTELFDEWGEYLAKTGGEVGVTTGRARRCGWFDAVIARYATRV 321
Cdd:cd03108 193 NTTAGGVCTGLGIPPRRVDRVIGVVKAYTTRVGSGPFPTELFDEEGEKLRELGHEYGTTTGRPRRCGWLDLVALRYAVRI 272
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 322 NGITDYFLTKLDVlsslervpicvayevdgervdempmtqtgfhhakpiyetmpgwwedisecrrfedlpqNAQNYILRL 401
Cdd:cd03108 273 NGLTELALTKLDV----------------------------------------------------------NAQKYIERI 294
|
410 420
....*....|....*....|..
gi 1799598060 402 EELSGAHISCIGVGPGRDQTIV 423
Cdd:cd03108 295 EELLGVPITYISVGPDREQTII 316
|
|
| PRK13786 |
PRK13786 |
adenylosuccinate synthetase; Provisional |
5-422 |
1.39e-146 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 184325 Cd Length: 424 Bit Score: 423.44 E-value: 1.39e-146
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 5 VLIGAQWGDEGKGKATDLLGGRLQWVVRYQGGNNAGHTVVLpSGETFALHLIPSGILTRGvNNVIGNGVVVDPGVLLTEL 84
Cdd:PRK13786 4 IITGAQFGDEGKGKIVDLLAKDYDIVARFQGGDNAGHTVKV-GDEVYKLHLIPSGFLLDA-RVLIGPGVVLNPEVLAEEI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 85 SGLEER--DVDTTGLMISADAHLLMPYHVAIDKVTERFLgNKKIGTTGRGIGPCYQDKIARGGVRVADVLDEKILSQKV- 161
Cdd:PRK13786 82 DMLEKHgvKVDAEKLGIDAKTSIIMPYHIELDGLRESAR-TEKIGTTKRGIGFAYIDKIARDEVRMSDLVDKERLMRRLe 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 162 EAALELKNQIlvkiynrKAL--EPARVVDEVLAQA-----EGFSHRIADTRLLLNQALERGETVLLEGSQGTLLDVDHGT 234
Cdd:PRK13786 161 ELAPQKEKEI-------KELggDPSIVRDEALIDKylelgRQLAPYITDVSYEINKALDEGKSVLAEGAQGTHLDVIHGT 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 235 YPYVTSSNPTAGGAAVGSGIGPNKITTVLGILKAYTTRVGSGPFPTELFDEWGEYLAKTGGEVGVTTGRARRCGWFDAVI 314
Cdd:PRK13786 234 QKFVTSSSTIAGSACANLGVGPTRVDNVLGIVKAYITRVGEGPLPTELKDEAGEHLQDVGGEFGTTTGRPRRCGWFDLPL 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 315 ARYATRVNGITDYFLTKLDVLSSLERVPICVAYEVDGERVDEMPMTQTGFHHAKPIYETMPGWWEDISECRRFEDLPQNA 394
Cdd:PRK13786 314 LKKAIYLNGYTEIALTKLDVLTGLDPIKICVGYELDGEILDYPPELTSDLARCVPVYEELEGWSTDLTEVKAYEDLPENA 393
|
410 420
....*....|....*....|....*...
gi 1799598060 395 QNYILRLEELSGAHISCIGVGPGRDQTI 422
Cdd:PRK13786 394 RNYVERLEELMGVPIKYISVGPGREQTF 421
|
|
| PRK13787 |
PRK13787 |
adenylosuccinate synthetase; Provisional |
1-423 |
1.59e-146 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 172324 Cd Length: 423 Bit Score: 423.59 E-value: 1.59e-146
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 1 MAAIVLIGAQWGDEGKGKATDLLGGRLQWVVRYQGGNNAGHTVVLpSGETFALHLIPSGILTRGVNNVIGNGVVVDPGVL 80
Cdd:PRK13787 1 MPASLVVGTQWGDEGKAKVIDFLSKDTDIIVRYQGGANAGHTVVV-HGKKYVFHLVPSGVIYDQTICVIGNGVVLDPLFF 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 81 LTELSGLEERDVDTTG-LMISADAHLLMPYHVAIDKVTERFLG-NKKIGTTGRGIGPCYQDKIARGGVRVADVLDeKILS 158
Cdd:PRK13787 80 IEECDRLQKEGFPVKDkLLLSDACHLLFPYHSQIDSARETTSSqEHKIGTTKKGIGICYADKMMRTGLRVGDLLD-KSYK 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 159 QKVEAALELKNQILVKIYNRKALEPARVVDEVLAQAEGFSHRIADTRLLLNQALERGETVLLEGSQGTLLDVDHGTYPYV 238
Cdd:PRK13787 159 RRLKHLVDEKNRELDKLYGMPPVSYNDINDGLKFFLSKVGKNIINTAYYLDTELKKGKRVLLEGAQGTGLDVDFGTYPYV 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 239 TSSNPTAGGAAVGSGIGPNKITTVLGILKAYTTRVGSGPFPTELFDEWGEYLAKTGGEVGVTTGRARRCGWFDAVIARYA 318
Cdd:PRK13787 239 TSSNPTTGGALIGTGISFQHLKHVIGITKAYTTRVGEGPFPTELLGEAGEVLRQKGGEFGATTGRPRRCGWFDVEMLKHS 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 319 TRVNGITDYFLTKLDVLSSLERVPICVAYEVDGERVDEMPmtQTGFHHAKPIYETMPGWWEDISECRRFEDLPQNAQNYI 398
Cdd:PRK13787 319 VRINGITSIALTKIDILSDYDTIPVAVGYKLNGKTLDCFP--SQGLEKVEPLYEEFPGWKDDISGINEFQKLPEKCKNYI 396
|
410 420
....*....|....*....|....*
gi 1799598060 399 LRLEELSGAHISCIGVGPGRDQTIV 423
Cdd:PRK13787 397 SALEKWIGVKINLVSTGPDRKDTII 421
|
|
| PRK13788 |
PRK13788 |
adenylosuccinate synthetase; Provisional |
1-421 |
1.67e-130 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 184326 [Multi-domain] Cd Length: 404 Bit Score: 381.85 E-value: 1.67e-130
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 1 MAAIVLIGAQWGDEGKGKATDLLGGRLQWVVRYQGGNNAGHTVVLpSGETFALHLIPSGILTRGVNNVIGNGVVVDPGVL 80
Cdd:PRK13788 1 MPGIAIIGAQWGDEGKGKVVDALAPEADFVVRYQGGANAGHTVVA-KGKTFKLNLLPSGVLHPHATSVLGDGMVIDPFRF 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 81 LTELSGLEERDVDTTgLMISADAHLLMPYHVAIDKvterflGNKKIGTTGRGIGPCYQDKIARGGVRVADVLDEKILSQK 160
Cdd:PRK13788 80 AEERENLRAGGLNPK-LLISERAHLVLPHHKYVDG------RKNFVGTTGRGIGPAYSDRARRVGIRFGDLLDEAVLRER 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 161 VEAALELKNQILVKI---YNRKALEPARVVDEVLAQAegfshrIADTRLLLNQALERGETVLLEGSQGTLLDVDHGTYPY 237
Cdd:PRK13788 153 VERLLEAKPNSTREAgwdTVEKALADLAPMREILLPF------IADTGSLLREAIREGKRVLFEGAQATLLDLNYGTYPY 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 238 VTSSNPTAGGAAVGSGIGPNKITTVLGILKAYTTRVGSGPFPTELFDEWGEYLAKTGG----EVGVTTGRARRCGWFDAV 313
Cdd:PRK13788 227 VTSSHPTVGGILVGAGVNHKAINKVYGVAKAFTTRVGHGPFPTEVFGEMAIRLRGKGGnpwdEFGTTTGRARRVGWLDLV 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 314 IARYATRVNGITDYFLTKLDVLSSLERVPICVAYEVDGervdempmtqtgfhhaKPIYETMPGwWEDISECRRFEDLPQN 393
Cdd:PRK13788 307 LLKYACEVNGFDGLVLTKLDVLSGLEKVKVCVEYDDDG----------------QPVYKELPG-WGDLDGVKSREALPKE 369
|
410 420
....*....|....*....|....*...
gi 1799598060 394 AQNYILRLEELSGAHISCIGVGPGRDQT 421
Cdd:PRK13788 370 AQAYLELIEETTGVPVVMFSTSPRREDT 397
|
|
| PRK13785 |
PRK13785 |
adenylosuccinate synthetase; Provisional |
4-424 |
3.49e-128 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 237506 Cd Length: 454 Bit Score: 377.95 E-value: 3.49e-128
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 4 IVLIGAQWGDEGKGKATDLLGGRLQWVVRYQGGNNAGHTVVlPSGETFALHLIPSGILtRGVNNVIGNGVVVDPGVLLTE 83
Cdd:PRK13785 3 VTIVGSQLGDEGKGGVVDLYGDAADVVVRYQGGDNAGHTVV-HGGEEYKLSLVPSGAV-RGKIGVLGNGCVVNPETLFDE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 84 LSGLEERDVDTTgLMISADAHLLMPYHVAIDKVTERFLG--NKKIGTTGRGIGPCYQDKIARGGVRVADVLDEKILSQKV 161
Cdd:PRK13785 81 IDALRERGLDPD-VRVAERAHVILPYHRVLDGIEEEAKSdsDLEVGTTGRGIGPTYEDKAGRRGVRVGDLLDPDVLRDRL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 162 EAALELKNQILVKIYNRKALEPARV--VDEVLAQAEGFSHRIADTRL------LLNQALERGETVLLEGSQGTLLDVDHG 233
Cdd:PRK13785 160 EYVVPQKRALAEDVYGLDASETPEAfdVDALFEEYREYGERLAEEDMtvnagdFLAERIDDGDNVMLEGAQGTSIDIDHG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 234 TYPYVTSSNPTAGGAAVGSGIGPNKIT--TVLGILKAYTTRVGSGPFPTEL---------------FDEWGEYLAKTGGE 296
Cdd:PRK13785 240 NYPYVTSSNPTAGGAATGTGLGPTVVGqgEVVGIVKAYLSRVGSGPLPTELggvegdtpdeggrpdEEELATYIREEGGE 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 297 VGVTTGRARRCGWFDAVIARYATRVNGITDYFLTKLDVLSSLERVPICVAYEVDGERVDEMPMTQTGFHHAKPIYETMPG 376
Cdd:PRK13785 320 YGTVTGRPRRVGWLDMPMLRHAARASGFTGLAINHIDVLAGLDEVKVGHSYELDGEELLTMPATTERWARCEPNFRSFDG 399
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|..
gi 1799598060 377 W----WEDISEcRRFEDLPQNAQNYILRLEELSGAHISCIGVGPGRDQTIVR 424
Cdd:PRK13785 400 WpevdWAAVAE-EGYDALPENARTYLEYVSDELDTPIYAVGVGPGREETVVL 450
|
|
| PRK13783 |
PRK13783 |
adenylosuccinate synthetase; Provisional |
4-422 |
2.19e-125 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 237505 Cd Length: 404 Bit Score: 369.05 E-value: 2.19e-125
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 4 IVLIGAQWGDEGKGKATDLLGGRLQWVVRYQGGNNAGHTVVLpsgETFAL--HLIPSGILTRGVNNVIGNGVVVDPGVLL 81
Cdd:PRK13783 3 RVIVGLQWGDEGKGKVVTYLSRYYDIVVRYSGGANAGHTVNY---GDFKVvhHLLPSADFKKNVGAAIGNGVVLDLEVLV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 82 TELSGLEERDVDTTG-LMISADAHLLMPYHVAIDKVTERFLGNKkIGTTGRGIGPCYQDKIARGGVRVADVLDEKILSQK 160
Cdd:PRK13783 80 EELEELKEKFPDYSGrIFISELAHVVLPVHKELDEIIESVRKNA-IGTTKRGIGPAYADKVMRVGVRLADLFDEEKLREF 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 161 VEAALELKNqilvKIYNRKaLEPARVVDEVLAQAEGFSHRIADTRLLLNqaLERGETVLLEGSQGTLLDVDHGTYPYVTS 240
Cdd:PRK13783 159 LEKILSLYK----KLYGIE-FDVEKMMEDLLTFYEKIKDLVVSPVEIKR--ILEEKSVLFEGTQGVLLDLDVGTYPYVTS 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 241 SNPTAGGAAVGSGIgPNKITTVLGILKAYTTRVGSGPFPTELFDEWGEYLAKTGGEVGVTTGRARRCGWFDAVIARYATR 320
Cdd:PRK13783 232 SNCSTTGVSAGMGF-PVKVDEVIGVFKAYTTRVGEGPFPTELFGEEGEKLRKAGHEYGATTGRPRRCGWLDLPLLRYAIE 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 321 VNGITDYFLTKLDVLSSLERVPICVAYEVDGERVDeMPMTQTGFHHAKPIYETMPGwWEDISEcrrfedlpQNAQNYILR 400
Cdd:PRK13783 311 VSGVDSLVMTKADVLNGFEKIKVCVRYEIGGKEVR-DPSSLRDLEKAEPVYEEFDG-WKSLED--------KNFLKFVDF 380
|
410 420
....*....|....*....|..
gi 1799598060 401 LEELSGAHISCIGVGPGRDQTI 422
Cdd:PRK13783 381 IERETGRKIAYISTGPKIEEIV 402
|
|
| PRK13784 |
PRK13784 |
adenylosuccinate synthetase; Provisional |
1-426 |
9.16e-106 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 172322 Cd Length: 428 Bit Score: 319.66 E-value: 9.16e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 1 MAAIVLIGAQWGDEGKGKATDLLGGRLQWVVRYQGGNNAGHTVVLPSGETFaLHLIPSGILTRGVNNVIGNGVVVDPGVL 80
Cdd:PRK13784 1 MSNIVIVGAQWGDEGKGKIADTLAEKADLVVRYQGGNNAGHTLVVNGKKTF-LHLIPSGVLHQHTKCVIGHGVVLDPVAL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 81 LTELSGLEERDVDTTG--LMISADAHLLMPYHVAIDKVTERFLgNKKIGTTGRGIGPCYQDKIARGGVRVADVLDEKILS 158
Cdd:PRK13784 80 DEEITRLQAKGIAISAenLFVSESCTIITSYHKLLDAVRESNT-SEKIGTTGKGIGPAYEDKVSRKGIKFKHLFDKDLLR 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 159 QKVEAALELKNQILVKIYNRKALEPARVVDEVLAQAEGFSHRIADTRLLLNQALERGETVLLEGSQGTLLDVDHGTYPYV 238
Cdd:PRK13784 159 SRLAISLAEKETLFRDLYKVEYPTLEQEFDKLFALGQKLKQYAADTFSIIDQAIAAGKNVVYEGAQGVLLDVDYGTYPFV 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 239 TSSNPTAGGAAVGSGIGPNKITTVLGILKAYTTRVGSGPFPTELFDEWGEYLAKTGGEVGVTTGRARRCGWFDAVIARYA 318
Cdd:PRK13784 239 TSSNTSVAGVYSGATTAGHGLDHVIGITKAYTTRVGEGPFPTELFDDVGKFIQHKGGEIGVTTGRIRRCGWLDLPLLKYS 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 319 TRVNGITDYFLTKLDVLSSLERVPICVAYEVDGERVdEMPMTQTGFHHAKPIYETMPGWweDISECRRFEDLPQNAQNYI 398
Cdd:PRK13784 319 AKCSNLTSIALTKVDVLSDMDTLKVCIGYKYEGKEI-YCAYPGIDLYKVEPILVEMEPF--SIDETVTKDNMPAALKTYL 395
|
410 420
....*....|....*....|....*...
gi 1799598060 399 LRLEELSGAHISCIGVGPGRDQTIVRRD 426
Cdd:PRK13784 396 KTIENHVGIPISSLAYGPSREQILFFED 423
|
|
| PRK04293 |
PRK04293 |
adenylosuccinate synthetase; Provisional |
1-425 |
2.17e-75 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 179812 Cd Length: 333 Bit Score: 238.24 E-value: 2.17e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 1 MAAIVLIGAQWGDEGKGKATDLLG--GRLQWVVRYQGGNNAGHTVVLpSGETFALHLIPSGILTRGVNNVIGNGVVVDPG 78
Cdd:PRK04293 1 MTCTIVVGGFFGDEGKGKIIAYLAlkDKPSIIARGGVGPNAGHTVEY-NGKKYGLRMIPSGFVNKDAKLAIGAGVLVDPE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 79 VLLTELSGLEERDvdttGLMISADAHLLMPYHVAIDKVTERFLgnKKIGTTGRGIGPCYQDKIARGGVRVADVldekils 158
Cdd:PRK04293 80 VLLKEVEELNVGG----RVFVDYRCGIIEEKHVEEDRSDEHLS--KKIGSTGTGCGPANADRVLRRLKLAKDV------- 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 159 qkveaalelknqilvkiynrKALEPArvvdevlaqaegfshrIADTRLLLNQALERGETVLLEGSQGTLLDVDHGTYPYV 238
Cdd:PRK04293 147 --------------------EELEKY----------------LTDVPEEVNEALDRGENVLIEGTQGFGLSLYYGTYPYV 190
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 239 TSSNPTAGGAAVGSGIGPNKITTVLGILKAYTTRVGSGPFPTELFDEWGEYLAKTggEVGVTTGRARRCGWFDAVIARYA 318
Cdd:PRK04293 191 TSKDTTASGIASDVGVGPTKVDEVIVVFKSYPTRVGEGPFPTELSLEEAEKLGLV--EYGTVTGRRRRVGPFDFELARRA 268
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 319 TRVNGITDYFLTKLDVLsslervpicvayevdgervdempmtqtgfhhakpiyetmpgwWEDISECRRFEDLPQNAQNYI 398
Cdd:PRK04293 269 ARINGATQIAITKLDKL------------------------------------------DKEAYGVTEYDKLPPEAKKFI 306
|
410 420
....*....|....*....|....*..
gi 1799598060 399 LRLEELSGAHISCIGVGPGRDQTIVRR 425
Cdd:PRK04293 307 EEIEEELGVPVTLISTGPELEDTIDLR 333
|
|
| PTZ00351 |
PTZ00351 |
adenylosuccinate synthetase; Provisional |
4-425 |
1.03e-29 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 173544 Cd Length: 710 Bit Score: 122.08 E-value: 1.03e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 4 IVLIGAQWGDEGKGKATDLLGGR--LQWVVRYQGGNNAGHTVVLPSGETFALHLIPSGILTRGVNNVIGNGVVVDP-GVL 80
Cdd:PTZ00351 172 IMVAGAFFGDEGKGKTVDAVAHHplCTCIARVNSGENAGHTVYDKAGRKFVFNLAPSGLLLPGKRNYIGPECVMDPvSFM 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 81 LTELSGLEERDVDTTGLMISADAHLLMPYHVAIDkvterFLGNKKIGTTGRGIGPCYQDKIARGGVRVADVL-DEKILSQ 159
Cdd:PTZ00351 252 EKEIIQLIDAGIDYRDRLFIGNVCIVTPYHKLLD-----LLGSAANSSTLKGMAPVHGSKVMKRGIRLDHIFnDDETLRK 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 160 KVEAALE----------LKNQILVKIYNRKALEPA-RVVDEVLAQAEG----------FSHRI---------ADTRLLLN 209
Cdd:PTZ00351 327 RLEKDMDtylgllkvknLSDADVVRLCREENSDGVvRVPDYVIAFAQAkdkveflvklYRDRVrhnpdfparCDVTYELH 406
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 210 QALERGETVLLEGSQGTLL-DVDHGTYPYVTSSNPTAGGAAVGSGIGPNKI-TTVLGILKAY-TTRVGSG---------- 276
Cdd:PTZ00351 407 AAVLRGEKVLLEGPQSYWLsNARTKFWESTTSADTTAAGLLAASQLNFQKFkSVVLNVHKAPgSSRVGIGacpssfvpqd 486
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 277 ---------------------------------PF------------PTELFDEWGEY---------LAKTGGEVGVTTG 302
Cdd:PTZ00351 487 yfsaqniktlrdlpsatcanfeavqrtlfrdgfPHsndkarhngimaPVEYSDETGDYnigvamaiaSAQHHGECGAVTK 566
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 303 RARRCGWFDAVIARyatRVNGITDYFLT--KLDVLSSLERVPICVA---YEVDGERV----------------DEMPmTQ 361
Cdd:PTZ00351 567 KPRVCGFFDCVLQH---EVNSIQGPYLTisALDRGDEYDKVGVTIAyvyYNPEGKQVdvnghvykngdiiragDPVP-SE 642
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1799598060 362 TGFHHAKPIYETMPGWWED---ISECRRFEDLPQNAQNYILRLEELSGAHISCIGVGPGRDQTIVRR 425
Cdd:PTZ00351 643 PALYHCHPIVKLIDGWRDNpiaAAKRRRNAPLPRGVCELLSTIEYFTNCKILSIGNGPNGDDIIYLR 709
|
|
| amino_Aden_PurZ |
NF038379 |
succino-amino-deoxyadenylate synthase PurZ; |
3-323 |
5.39e-26 |
|
succino-amino-deoxyadenylate synthase PurZ;
Pssm-ID: 468496 Cd Length: 292 Bit Score: 106.69 E-value: 5.39e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 3 AIVLIGAQWGDEGKGKATDLLGGRLQWVVRYQ-GGNNAGHTVVLPSGETFALHLIPSGILTRGVNNV-IGNGVVVDPGVL 80
Cdd:NF038379 1 VDVVVDGQFGSTGKGLIAGYLAERAAPDVVVRaAGPNAGHTYIDDEGRKFVHRMLPNGIVSPPLKQVlIGPGSEIDLEVL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 81 LTELSGLEERDVDT-TGLMISADAHLLMPYHvaidKVTERFLGNKKIGTTGRGIGPCYQDKIARGGVRVADVLDEKILSQ 159
Cdd:NF038379 81 REEIEELEDAGHDVgKRLLIHEQATVIELHK----HVEEEAGPMTKIGSTKKGIGAARAAKIRRNPSTLGDAEGDFGEGA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 160 KVEAALELknqilvkiynrkalePARVVDEVLAQaegfshriadtrlllnQALERGETVLLEGSQGTLLDVDHGTYPYVT 239
Cdd:NF038379 157 VRDQPWEI---------------AERVVDNALYD----------------FALQAAERIQIEGTQGYSLGLHAGFYPYCT 205
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799598060 240 SSNPTAGGAAVGSGIGPN--KITTVLGILKAYTTRVG-----SGPFPTEL-FDEWGEYLAKTggevgVTTGRARRCGWFD 311
Cdd:NF038379 206 SRDCTPADFLADAGIPLPnvDAFKVVGTARTYPIRVAgwsgnSYPDQGETtWEELGLPEELT-----TVTKKVRRVGTFS 280
|
330
....*....|..
gi 1799598060 312 AVIARYATRVNG 323
Cdd:NF038379 281 AEQVREAVQANG 292
|
|
| |
